Disclosed in the present invention are a geographic position-based high-speed rail mobile communication 6G fully-decoupled network uplink transmission method and system. The method comprises: according to geographic positions of a train and each uplink base station, performing line-of-sight channel mapping, so as to serve as channel estimation to carry out a secondary combining joint reception processing of the uplink signals; designing a deep learning neural network, taking the mapped line-of-sight channel as an input, and outputting a multi-user joint precoding that meets constraint conditions; performing offline training on a network by using historical channel data of each position; in an actual deployment stage, inputting a line-of-sight channel corresponding to the train position, the network outputting a joint precoding at the corresponding position, so as to achieve transmission without feedback. Compared with a traditional precoding design solution, the present invention solves the problem in a high-speed rail scenario of untimely channel feedback and large resource overhead due to high-speed movement, improves the frequency effect of wireless communication in a high-speed rail scenario, and provides an effective uplink transmission method for future high-speed rail mobile communications.
A method for reducing mDON concentration in wastewater, including a) acquiring a kinetics associated with production and consumption of a mDON of an activated sludge system, and importing a kinetic expression of the mDON into a conventional activated sludge model No. 1 (ASM1) to build a kinetic equation for the mDON; b) inputting component variables, parameter variables, model matrices, process rate equation and operating parameters of a predictive model into a simulation software to build an ASM-mDON model; c) inputting initial values of the component variables and the parameter variables into the simulation software for model initialization; d) acquiring initial mDON kinetic and sensitivity analysis results, selecting corresponding parameters, calibrating kinetic and stoichiometric parameters of the ASM-mDON model using a parameter estimation function of the simulation software; and e) replacing the initial values of the ASM-mDON model with optimal values obtained in d).
The present invention belongs to the technical field of nanobodies, and specifically relates to an anti-ouabain nanobody and the use thereof. The amino acid sequence of the anti-ouabain nanobody is as shown in SEQ ID NO. 1. The nucleotide sequence thereof is as shown in SEQ ID NO. 2. The antibody has a good affinity to ouabain, can neutralize and antagonize the pharmacological activity of ouabain, and can be used to detect the content of ouabain in a solution in combination with an ELISA method. The present invention provides a method for constructing an ouabain antibody having a light weight, a high thermostability and a high detection sensitivity, and provides a research tool for deeply exploring the new biological functions of endogenous ouabain.
The present invention relates to a double-acid catalyst and a method for preparing furfural by catalyzing hemicellulose or xylose. The double-acid catalyst comprises choline chloride, a Bronsted acid, and a Lewis acid at a molar ratio of 1:1:1-4, and is in a deep eutectic state. The method comprises the following steps: adding into a reaction kettle a hemicellulose or xylose raw material, and the double-acid catalyst as a water phase, then adding an oil phase extraction agent, and carrying out catalytic dehydration and hydrolysis reactions in the reaction kettle to generate furfural, wherein the oil phase extraction agent continuously extracts the furfural from the water phase in the reaction process until the reaction is finished. According to the present invention, the choline chloride is combined with the Lewis acid and the Bronsted acid to form a deep eutectic solvent as the double-acid catalyst, and the deep eutectic solvent is used in the process of preparing furfural by catalyzing hemicellulose or xylose, thereby reducing the activation energy required by the reaction, and increasing the yield of the furfural. In addition, the water phase and the catalyst in the preparation process can both be recycled, thereby reducing the energy consumption and the production cost.
B01J 31/34 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups of chromium, molybdenum or tungsten
The present invention belongs to the technical field of wastewater treatment and more specifically relates to a method for accurately controlling dissolved oxygen of an aerobic wastewater treatment system. The system integrates the functions of online monitoring and dissolved oxygen control of system parameters of a wastewater treatment plant, can acquire data of the dissolved oxygen concentration, openings of air valves, air quantity of a fan, influent quality and quantity of the wastewater treatment system in real time, automatically calculates ideal values of the air quantity of the fan and the openings of the air valves according to a target value of the dissolved oxygen concentration by a server, screens an optimal adjusting mode on the basis of a certain condition, and finally sends an instruction to the fan or the air valves to realize the accurate control of dissolved oxygen of the wastewater treatment system.
A method for producing an electrochemiluminescence nanoprobe according to an embodiment includes: a hot exciton nanoparticle synthesis step of polymerizing a hot exciton organic luminescent molecule and a copolymer molecule to synthesize hot exciton nanoparticles; and a hot exciton nanoparticle modification step of modifying the obtained hot exciton nanoparticles with an oligonucleotide chain modified with a quencher molecule to obtain modified hot exciton nanoparticles.
C09K 11/07 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
C08F 8/34 - Introducing sulfur atoms or sulfur-containing groups
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
An alternating electric field-driven gallium nitride (GaN)-based nano-light-emitting diode (nanoLED) structure with an electric field enhancement effect is provided. The GaN-based nanoLED structure forms a nanopillar structure that runs through an indium tin oxide (ITO) layer, a p-type GaN layer, a multiple quantum well (MQW) active layer and an n-type GaN layer and reaches a GaN buffer layer; and the nanopillar structure has a cross-sectional area that is smallest at the MQW active layer and gradually increases towards two ends of a nanopillar, forming a pillar structure with a thin middle and two thick ends. The shape of the GaN-based nanopillar improves the electric field strength within the QW layer in the alternating electric field environment and increases the current density in the QW region of the nanopillar structure under current driving, forming strong electric field gain and current gain, thereby improving the luminous efficiency of the device.
H01L 33/08 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a plurality of light emitting regions, e.g. laterally discontinuous light emitting layer or photoluminescent region integrated within the semiconductor body
H01L 33/00 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof
H01L 33/02 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies
H01L 33/06 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a quantum effect structure or superlattice, e.g. tunnel junction within the light emitting region, e.g. quantum confinement structure or tunnel barrier
H01L 33/12 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a stress relaxation structure, e.g. buffer layer
H01L 33/24 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a particular shape, e.g. curved or truncated substrate of the light emitting region, e.g. non-planar junction
H01L 33/32 - Materials of the light emitting region containing only elements of group III and group V of the periodic system containing nitrogen
The present invention relates to the field of material preparation. Disclosed are a poly(carbazole phosphonic acid) material and a preparation method therefor and a use thereof. The poly(carbazole phosphonic acid) material provided by the present invention has better stability, and the good film-forming property of the said material and the interaction between macromolecular chains can effectively solve the problems of poor compactness, easy diffusion and the like of traditional carbazole phosphonic acid small molecules, thereby producing a stable photoelectric device based on poly(carbazole phosphonic acid). The synthesis method for poly(carbazole phosphonic acid) is simple and rapid and involves mild reaction conditions. An obtained poly(carbazole phosphonic acid) material is dissolved in methylbenzene, chlorobenzene, chloroform, dichloromethane, methanol, ethanol, isopropanol and other single or mixed solvents, and is processed into thin films by means of processes such as spin coating, blade coating, slit coating, dip coating, spraying, and then a photoelectric device based on the poly(carbazole phosphonic acid) material is prepared. The present application has important scientific significance and an extremely high industrial value.
H10K 30/20 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising organic-organic junctions, e.g. donor-acceptor junctions
10.
SYNTHESIS METHOD FOR LAYERED BIMETAL-BASED NANO LANTHANUM MATERIAL THAT SYNCHRONOUSLY LOCKS PHOSPHORUS, REMOVES ALGAE AND REDUCES TURBIDITY, AND USE THEREOF
33 thin film thicknesses; in addition, the solution can greatly improve the flexibility in design, compactness, mechanical stability, temperature stability and power tolerance of devices.
A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
C07C 309/81 - Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
The present invention discloses an in-situ testing system for semiconductor device in aerospace irradiation environment. The present invention includes a static testing unit, a static testing channel, a dynamic testing unit, a dynamic testing channel, and a channel switching control unit; the static testing unit is connected to the device under test through the static testing channel, and is used to output static testing signals and display the static testing data of the device under test; the dynamic testing unit is connected to the device under test through the dynamic testing channel, and is used to output dynamic testing signals and display the dynamic testing data of the device under test; the channel switching control unit is connected to the static testing channel and the dynamic testing channel, respectively. This invention can achieve static, dynamic, and degradation testing of third-generation semiconductor device in aerospace irradiation environment.
Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
An ocean current detection device and method based on double-helix and double-core vibration fiber-optic cable, comprises a double-core fiber-optic cable and a φ-OTDR system; the double-core fiber-optic cable comprises a first and a second optical fiber core, provided symmetrically in the double helix structure. The terminate ends of the first and the second optical fiber core are connected, and the start end of the first or the second optical fiber core is connected with the φ-OTDR system. When measuring the ocean current characteristics in the target sea area, the double-core fiber-optic cable is provided underwater to generate vortex-induced vibration. The φ-OTDR system is provided for emitting laser towards the cable, receiving returned double-core vibration signals, extracting vibration characteristics from the double-core vibration signals to determine ocean current characteristics, including ocean current flow velocity and direction, to improve the detection accuracy.
G01P 5/26 - Measuring speed of fluids, e.g. of air streamMeasuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring the direct influence of the streaming fluid on the properties of a detecting optical wave
G01P 13/02 - Indicating direction only, e.g. by weather vane
16.
MONITORING SYSTEM AND METHOD FOR BROKEN WIRES IN PCCP BASED ON DISTRIBUTED OPTICAL FIBER SENSING
A monitoring system and method for broken wires in PCCP based on distributed optical fiber sensing relates to the technical field of optical fiber sensing. The monitoring system for broken wires in PCCP comprises a Sagnac interferometer, a Φ-OTDR system, a dual loopback system and a signal processing system. The Sagnac interferometer comprises a first laser, a first optical coupler, a first delay optical fiber, a Faraday rotating mirror and a first photodetector. The Φ-OTDR system comprises a second laser, a second optical coupler, an acousto-optic modulator, a circulator, a third optical coupler and a second photodetector. The dual loopback system comprises a wavelength division multiplexer and a second delay optical fiber. The invention solves the problems of low positioning accuracy, limited frequency measurement range, detection dead zone and high computing pressure in monitoring broken wires in PCCP.
CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE (China)
HUAZHONG AGRICULTURAL UNIVERSITY (China)
Inventor
Dong, Xianchi
Liu, Wen
Ding, Jianping
Shi, Yu
Xu, Shutong
Xu, Jianbo
Abstract
Provided are a protein containing an amino acid sequence capable of binding to a peptide fragment of a substrate GPRP, a fibrinogen-like protein 1 (FGL1) containing the amino acid sequence, and a fibrinogen domain (FD) of the FGL1, wherein a single FD protein also has a function the same as or similar to that of the FGL1. The FGL1 and FD, which have different action mechanisms from existing drugs, can inhibit fibrin assembly in the process of thrombogenesis by means of competing for fibrin substrate binding pockets. The FGL1 and FD can have a stronger affinity to the substrate by means of mutation, thereby effectively enhancing a usage effect of drugs for treating thrombus.
Disclosed in the present invention are a method and device for imaging and calculation, and a computer readable medium. The method comprises: extracting a field of view image of a target field of view, and searching the field of view for a specific target; according to the attribute of the specific target, determining a calculation kernel corresponding to the specific target, wherein the calculation kernel is expressed by a weight value matrix; performing convolution calculation in an imaging region by using the calculation kernel; and performing searching and matching on the field of view image to obtain a feature map corresponding to the specific target.
The present invention provides a method and a system for predicting carbon emission from agricultural land, relates to the technical field of carbon emission prediction, comprising: Using the CLUMondo model to predict the agricultural land area of the target area at a future time; Determining methane emissions from paddy fields at a future time based on the area of rice planted in the agricultural land area; Determining the direct and indirect nitrous oxide emissions at a future time based on the nitrogen input to the agricultural land area; Determining methane emissions from animal enteric fermentation, methane emissions from animal manure management, and nitrous oxide emissions from animal manure management based on the number of animals in the agricultural land area.
G06Q 10/04 - Forecasting or optimisation specially adapted for administrative or management purposes, e.g. linear programming or "cutting stock problem"
A metal-resin composite, a surface treatment method, and a substrate of a printed circuit board (PCB) for high-frequency and high-speed signal transmission comprise a surface-treated metal, and the surface-treated metal includes a nano-scale pore array that is used for filling of a resin and vertically extends from a surface to an interior of a metal, where nano-scale pillars are provided to extend from bottoms to openings of nano-scale pores of the nano-scale pore array. The pillar-in-pore structure makes a resin entering a nano-scale pore have an ultra-high anchoring effect on a resin body outside the nano-scale pore. Therefore, on the premise of not using an additive such as a T liquid or a coupling agent, the present disclosure greatly improves a tensile bonding strength at an interface between a resin body and a metal substrate, and also eliminates a decline in an interfacial bonding strength of a composite.
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mouldApparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
An arrayed nanopore micro-current signal parallel measurement apparatus (2), comprising a gating apparatus (A) of a nanopore multi-path measurement unit, a multi-path nanopore current signal amplifying and signal processing apparatus (C), a multi-path nanopore current signal acquisition apparatus (B), an FPGA control chip (12), and a single-chip microcomputer (14). The arrayed nanopore micro-current signal parallel measurement apparatus can achieve high-bandwidth amplification and measurement of an arrayed nanopore micro-current signal, and ensures a signal sampling bandwidth by means of the high sampling rates of a bandwidth compensation circuit and an analog-to-digital converter. The gating apparatus (A) of the nanopore multi-path measurement unit can acquire the nanopore micro-current signal of a specified channel in a directional or polling manner, thereby achieving grouping control and polling sampling of a multi-path nanopore detection system. The arrayed nanopore micro-current signal parallel measurement apparatus not only can be applied to acquisition and reading of micro-current signals in nanopore protein molecule sequencing, but also can be used for detection of other micro-current measurement systems such as ion channel drug screening and single-particle collision electrochemical detection.
Disclosed are a scenario test method and apparatus of a driving control system, a medium, and a device. According to the method, a state transition diagram is input, and then the test coverage of each state transition in the state transition diagram is gradually implemented on the basis of the state transition diagram and by means of a cyclic iterative variation of a scenario sample. When the cyclic iterative variation is performed, a simulation output of the scenario sample is used as a reference, so that an iterative process can quickly converge the purpose of corresponding state transitions thereof completing coverage testing. The present invention can visually test the processing capability and level of the driving control system for a driving environment, and has high test efficiency.
A nano porin-based high-throughput detection device, comprising a biochip (1), bilayer membranes (3), a micro-well group (12), micro-wells (7), and a pool body structure (13). One or more micro-well groups (12) are arranged on the biochip (1); the micro-well group (12) comprises a plurality of micro-wells (7); the whole pool body structure (13) is of a cylindrical structure with an upper opening and a lower opening; the pool body structure (13) is integrally tiled on the upper surface of the biochip (1) and is tightly connected to the biochip (1); an inner cavity of the pool body structure (13) is separately communicated with the plurality of micro-wells (7); a polar medium (4) containing porins (18) is injected into the inner cavity of the pool body structure (13); a micro-well opening (8) of each micro-well (7) is provided with a bilayer membrane (3); the porins (18) are inserted onto the bilayer membranes (3). According to the nano porin-based high-throughput detection device, the membrane forming throughput can be improved, the types of membranes formed at the same timer are increased, the membrane forming efficiency is improved, and various porins (18) can be accommodated.
G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variablesInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
24.
LAND USE STRUCTURE PATTERN LAYER MINING METHOD BASED ON GRAPH CONVOLUTIONAL NETWORK
The present invention relates to a land use structure pattern layer mining method based on a graph convolutional network, which comprises the following steps: obtaining land use data; constructing a graph structure; generating a label input model; training the label input model by means of a graph convolutional network model, and generating a graph embedding; utilizing a spatially constrained multivariate clustering method to perform separation on the graph embedding, and obtaining a layered partition structure from partitions to each level of sub-partitions; separately using land use type frequency characteristics for each year of land use data to construct region-level primitives for each region; and representing temporo-spatial changes to the land use structure of a region according to the changes to region-level primitives of said region in different years. The influence of multiple orders of neighboring areas are taken into account when the primitives are constructed, partitioning can be carried out according to differences in land use spatial structures, and layered land use structure patterns and dynamic characteristics thereof can be effectively mined.
NANJING STAR HIDDEN TECHNOLOGY DEVELOPMENT CO., LTD. (China)
Inventor
Lai, Yun
Wang, Cong
Chu, Hongchen
Mou, Wenri
Abstract
The present invention relates to a wave-absorbing structure and a device. The wave-absorbing structure comprises a metasurface structure and at least one wave-absorbing material provided on the metasurface structure; the metasurface structure is provided with a plurality of metasurface units, each metasurface unit has a corresponding regulation and control parameter, and the regulation and control parameter of each metasurface unit is configured to: convert, on the metasurface structure, an incident electromagnetic wave into at least one pair of surface waves which can be absorbed by the at least one wave-absorbing material; and the at least one pair of surface waves propagate in opposite directions along the metasurface structure and overlap at the position of the at least one wave-absorbing material. According to the wave-absorbing structure, a metasurface structure is use to replace a resonant cavity, an optical splitter and a phase shifter in a conventional laboratory structure, reducing the complexity of an electromagnetic wave-absorbing system, and successfully bringing a coherent wave-absorbing scenario into a general electromagnetic environment.
Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
H04L 9/06 - Arrangements for secret or secure communicationsNetwork security protocols the encryption apparatus using shift registers or memories for blockwise coding, e.g. D.E.S. systems
27.
TEMPERATURE MEASUREMENT METHOD AND APPARATUS BASED ON PASSIVE RFID TAG
A temperature measurement method based on a passive RFID tag. The method comprises: acquiring a circuit temperature feature of a tag multiple times, and establishing a tag temperature-feature correspondence; and estimating, by using the tag temperature-feature correspondence and the current circuit temperature feature of the tag, the temperature of an environment where the tag is located, wherein the circuit temperature feature of the tag is the persistence time within which a passive RFID tag can operate normally during a discharging process after the tag is fully charged. By means of the method, a robust and accurate temperature measurement is achieved, and a tag can be directly deployed on an existing commercial RFID device without modifying the hardware of the tag and a reader.
G01K 11/00 - Measuring temperature based on physical or chemical changes not covered by group , , , or
G06K 19/07 - Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards with integrated circuit chips
28.
IMAGING SYSTEM, PREPARATION METHOD, AND IMAGE CAPTURING APPARATUS
The present invention relates to an imaging system, a preparation method, and an image capturing apparatus. The imaging system successively comprises, from an object side to an image side along an optical axis: a light source, configured to provide light irradiated to a sample; an imaging lens group, configured to receive light transmitted by the sample to image the sample at least once; and a phase modulation unit, configured to modulate light transmitted by the imaging lens group to form an expected sample image on an imaging surface of the imaging system. A plane where the phase modulation unit is located and a plane where the light source is located are a pair of conjugate planes; no lens or lens group for Fourier transform is introduced into at least an optical path between the plane where the phase modulation unit is located and the imaging surface of the imaging system. According to the imaging system, more diverse imaging effects can be achieved without changing an original microscopic imaging optical path basically, the resolution reduction can be avoided, and the imaging quality can be improved.
Disclosed in the present application are an AC current sensor and a wireless charging chip. The AC current sensor includes an integrator circuit, a differentiator circuit, and a calibration circuit. The integrator circuit is configured to perform integration on a voltage on which filter processing is performed across an inductor in a TX coil. The differentiator circuit is configured to perform differentiation on a voltage on which filter processing is performed across a capacitor in the TX coil. The calibration circuit is configured to sample and compare output signals of the integrator circuit and the differentiator circuit, and adjust output results of the integrator circuit and the differentiator circuit until the output results are the same. In this case, the output result of the differentiator circuit may be used to calculation for a current flowing through the TX coil.
A method of characterizing an analyte or the interaction between the analyte and an agent in a nanopore system, wherein the nanopore system comprises a protein nanopore disposed in a membrane that separates a first conductive liquid medium from a second conductive liquid medium, wherein the protein nanopore is MspA, MspA homolog or variant thereof, wherein the analyte has an conformation and the analyte with the conformation can be accommodated in the vestibule of the MspA, the MspA homolog or the variant thereof but cannot translocate through the MspA, the MspA homolog or the variant thereof, the method comprising: i) applying an electrical potential difference between the first conductive liquid medium and the second conductive liquid medium to drive the analyte into the nanopore, and optionally contacting the agent with the analyte; ii) measuring an ionic current through the protein nanopore to provide a tested current pattern that contains at least ionic current measured during the analyte is in the vestibule of the MspA, the MspA homolog or the variant thereof; iii) associating the tested current pattern with at least one characteristic of the analyte or the interaction between the analyte and an agent.
A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1
A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1
A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1
wherein R is —F or —OH, and L2 is linked to R1, R3 or R2, a is an integer of 1 to 10, b, c is each independently an integer of 0 to 10, provided that b and c are not simultaneously 0. R1, R2, and R3, may independently be H, optionally substituted alkyl, or optionally substituted aryl, and R1, may be H or isotope thereof Δ C may link R1 and a C linking R2 form a ring.
A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
NANJING STAR HIDDEN TECHNOLOGY DEVELOPMENT CO., LTD. (China)
Inventor
Chu, Hongchen
Lai, Yun
Xiong, Xiang
Peng, Ruwen
Wang, Mu
Abstract
The present disclosure relates to a transmission structure and a preparation method thereof. The transmission structure includes a plurality of first transmission units and a plurality of second transmission units, and difference between a first transmission phase of a transmitted electromagnetic wave of the first transmission unit and a second transmission phase of a transmitted electromagnetic wave of the second transmission unit is the same or similar within a preset frequency range. The plurality of first and second transmission units are arranged randomly on a surface. The first transmission unit has a first matrix, a first medium block is disposed inside the first matrix, and a thickness of the first matrix between the first medium block and an electromagnetic wave incident surface of the first transmission unit is a non-zero first thickness. The second transmission unit has a second matrix, a second medium block is disposed inside the second matrix, a thickness of the second matrix between the second medium block and an electromagnetic wave incident surface of the second transmission unit is a non-zero second thickness, and the first and second thicknesses are configured to enable the first and second transmission units to have a large phase difference of reflected electromagnetic waves in a wide frequency range.
Disclosed in the present invention are a biological wastewater treatment process reconstruction method and system based on machine learning. The method comprises: collecting influent and effluent water basic quality, ecological risk and process information data in a biological wastewater treatment procedure, and performing data preprocessing; performing feature extraction on biological wastewater treatment processes and performing multi-unit representation; constructing effluent water basic quality prediction models and effluent water ecological risk prediction models of different biological treatment multi-unit combined processes, and inspecting whether same are up to standard; simulating and reconstructing different biological wastewater treatment short-range unit combined processes, and inspecting whether the effluent water quality is up to standard in scenarios with different influent water qualities; and assessing the ecological risk of reconstructed biological treatment short-range unit combined processes, the effluent water quality of which is up to standard, and determining an optimal biological wastewater treatment process. By means of the present invention, a new biological treatment process that meets the requirements of the effluent water basic quality being up to standard and the biological risk being the lowest can be determined for scenarios with different influent water qualities, thereby removing the selection limitation of existing biological treatment process methods.
A retinomorphic sensor array and a convolution method are used for image processing therefor, wherein the optoelectronic sensor has a vertically stacked heterostructure provided with a bottom electrode, a dielectric layer, a channel layer, a source electrode and a drain electrode on a base, the source and drain electrode are mutually opposite and are arranged at two ends of the channel layer, the bottom electrode, the source and drain electrode are made of a material used by a flexible electrode, an inert metal or a semimetal, the dielectric layer is made of an insulating material, the channel layer is made of a bipolar material, and the base comprises a substrate and an insulating material layer generated on a surface of the substrate.
H01L 31/113 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by field-effect operation, e.g. junction field-effect photo- transistor being of the conductor-insulator- semiconductor type, e.g. metal- insulator-semiconductor field-effect transistor
An isolated nucleic acid, a plasmid or viral vector thereof and a pharmaceutical composition thereof, and a method for treating a disease. The nucleic acid and the vector comprise at least one RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function, can be delivered into a host body, are enriched in an organ tissue of a host, and are self-assembled to form and secrete an exosome and target a target tissue, thereby treating the disease.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
Provided are an imaging method and apparatus, and a medium. The method includes: for a target field of view, performing photographing and quantification at a first resolution, to obtain a first image that has a first bit width; for the target field of view, performing photographing and differential processing at a second resolution, to obtain a second image that has a second bit width, wherein the differential processing includes: for a pixel point obtained by photographing at the second resolution, quantifying the difference between the pixel point and a neighboring pixel point of the pixel point, to obtain a quantified difference a value of a corresponding pixel point in the second image; and fusing the first image with the second image, to obtain a third image, wherein the first resolution is lower than the second resolution, and the first bit width is higher than the second bit width.
Embodiments of the present disclosure provide a detection device for laser spot welding micro-weld spot quality based on laser ultrasound. The device includes: a nanosecond pulsed laser configured to emit a laser; the polarizing beam splitter configured to perform a laser beam splitting, wherein a laser beam after performing the laser beam splitting by the polarizing beam splitter enter an energy detector and a beam splitter mirror, respectively; the beam splitter mirror configured to perform the laser beam splitting on the laser entering the beam splitter mirror, wherein a laser beam after performing the laser beam splitting enter a photodetector and a light reflecting mirror, respectively; an aperture configured for the laser beam passing through the light reflecting mirror, the laser passing through a scanning galvanometer to reach a multi-axis displacement platform; the multi-axis displacement platform configured to place and/or move a sample.
B23K 31/12 - Processes relevant to this subclass, specially adapted for particular articles or purposes, but not covered by any single one of main groups relating to investigating the properties, e.g. the weldability, of materials
38.
METHOD FOR CORRECTING DOT PRODUCT ERROR OF VARIABLE RESISTOR ARRAY
Disclosed is a method for correcting a dot product error of a variable resistor array. The method includes: (1) initializing and writing a target conductance matrix into the variable resistor array; (2) calculating an effective conductance matrix of the variable resistor array; and (3) comparing the effective conductance matrix obtained in step (2) with the target conductance matrix, finishing executing the method in a case that a convergence condition is satisfied, and otherwise, continuing to execute steps as follows: multiplying a difference matrix by an adjustment coefficient η, such that an error conductance matrix is obtained; adjusting a conductance matrix Gwrite of actual variable resistors to Gwrite=G′write− Gerror, where Gerror is the error conductance matrix, G′write is a conductance matrix actually written into variable resistors last time; and executing steps (2) and (3) repeatedly after adjustment until a stop condition in step (3) is satisfied.
G06F 7/544 - Methods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using non-contact-making devices, e.g. tube, solid state deviceMethods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using unspecified devices for evaluating functions by calculation
The present invention relates to the field of solid-phase extraction, and particularly to a solid-phase extraction material, and a preparation method and use thereof. The preparation method includes prepolymerizing the monomers N-vinylpyrrolidone and divinylbenzene in the presence of a chain transfer agent, adding prepolymer dropwise to an emulsion of monodispersed seed microspheres, swelling, and reacting to prepare white spheres; and functionalizing the white spheres, to obtain the solid-phase extraction material. The solid-phase extraction material prepared by the reaction has good spherical morphology, large specific surface area, and high ion exchange capacity. The prepared solid-phase extraction material functions in the separation and enrichment of PPCPs by means of a variety of forces with a high extraction rate. The extraction rate is basically maintained between 85% and 105%, and acidic, alkaline, neutral and amphoteric substances is capable of being selectively separated.
A bioorthogonal cycloaddition reaction is provided, as well as the use in assembly of TAC-type molecules and use in preparation of bioconjugates. A method of performing a coupling reaction, comprising providing a first structure comprising a dione group or derivative thereof and a second structure capable of providing anionic furan-2-olate or derivative thereof.
C07D 307/77 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
42.
Silicon carbide-based lateral PN junction extreme ultraviolet detector based on selective-area ion implantation, and preparation method thereof
The present invention discloses a novel silicon carbide-based lateral PN junction extreme ultraviolet detector with enhanced detection performance based on selective-area ion implantation, including an N-type ohmic contact lower electrode, an N-type substrate and a lightly-doped epitaxial layer which are connected sequentially from bottom to top, where the lightly-doped epitaxial layer is an N-type lightly-doped epitaxial layer or a P-type lightly-doped epitaxial layer; in a case that the lightly-doped epitaxial layer is an N-type or P-type lightly-doped epitaxial layer, a P-type or N-type well region is formed on the surface of the N-type or P-type lightly-doped epitaxial layer through the selective-area ion implantation, a P-type or N-type ohmic contact upper electrode is arranged on the P-type or N-type well region, and the P-type or N-type ohmic contact upper electrode is provided with a metal conductive electrode along its periphery.
H01L 31/103 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by only one potential barrier or surface barrier the potential barrier being of the PN homojunction type
A method for recycling silver from a waste IC chip include: heating to disassemble an IC chip, and crushing the IC chip into powders; adding the powders to a nitric acid solution, heating, centrifuging and collecting a first filtrate; adding soluble starch to the first filtrate, where a mass concentration ratio of the soluble starch to Fe in the first filtrate is 5.20-7.30; heating a resulting mixture to 130-175° C. for a first hydrothermal reaction, separating a precipitate from the first hydrothermal reaction and collecting a second filtrate; heating the second filtrate to 160-230° C. for a second hydrothermal reaction, separating a solid from the second hydrothermal reaction and collecting a third filtrate; drying, grinding, and sieving the solid to obtain silver powders; and adding alkali to the third filtrate to form a precipitate of Cu, and separating the precipitate to yield copper hydroxide.
B22F 9/04 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from solid material, e.g. by crushing, grinding or milling
B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
The present disclosure provides methods, compositions, and kits for high-throughput single-cell analysis, such as nucleic acid analysis. In some embodiments, methods, compositions and kits for indexing a plurality of samples are provided. In some embodiments, methods, compositions and kits for high-throughput single-cell nucleic acid analysis, such as RNA sequencing are provided. The present disclosure allows fast, efficient and convenient cell labeling and sample pooling without being limited by cell types.
C12Q 1/6881 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
45.
DISPLAY MODULE, BACKLIGHT MODULE AND DISPLAY APPARATUS
A display module, a backlight module and a display apparatus. The display module comprises a main waveguide (102), an external light source (101) enters a waveguide layer by means of the main waveguide (102), and multiple paths of secondary waveguides (111-119) are fanned out by means of a light beam coupling unit (103), each path of secondary waveguide (111-119) corresponding to one row of pixels; and a high-collimation light beam is output after light output from pixel waveguides (121-130) pass through a collimating lens (150) and a light beam conversion structure (160). The backlight module comprises a pixel display module and two layers of electrowetting prism arrays (4, 5), and the collimated decoherence light passes through the two layers of electrowetting prism arrays (4, 5) to achieve angular deflection in the XY direction. The display apparatus comprises a backlight module, and upper and lower polarizers (6, 10), upper and lower TFT glass substrates (7, 9), a liquid crystal layer (8), a color filter layer (11), and a display phase plate (12) which are arranged at the light exiting end of the backlight module. The light passes through the display phase plate (12) to form left and right eye fields of view, thus generating a real 3D effect. By means of voltage control, the present invention not only improves the resolution and observation field of view of 3D display, but also achieves free switching between a 2D observation mode and a 3D observation mode.
G02B 30/33 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving directional light or back-light sources
A light guide plate (100), a backlight module, and a display device. The light guide plate (100) comprises: a light incident surface (110); a light emergent surface (120) connected to the light incident surface (110); and a bottom surface (130) arranged opposite the light emergent surface (120). The bottom surface (130) comprises a first region (S region) and a second region (P region) which are sequentially arranged in a direction away from the light incident surface (110). The distance from any point in the first region (S region) to the light incident surface (110) is less than the distance from any point in the second region (P region) to the light incident surface (110). A plurality of first light guide points (140) and a plurality of second light guide points (150) are provided in the first region (S region). A plurality of first light guide points (140) are provided in the second region (P region). The first light guide points (140) have first reflective surfaces (141) facing the light incident surface (110). Included angles between the first reflective surfaces (141) and the bottom surface (130) are first included angles (α1). The second light guide points (150) have second reflective surfaces (151) facing the light incident surface (110). Included angles between the second reflective surfaces (151) and the bottom surface (130) are second included angles (α2). The first included angles (α1) and the second included angles (α2) are less than or equal to 5°. Furthermore, the first included angles (α1) are smaller than the second included angles (α2). The light guide plate (100) can achieve narrow viewing angle display without affecting light-emitting uniformity.
HAIAN INSTITUTE OF HIGH-TECH RESEARCH, NANJING UNIVERSITY (China)
Inventor
Tang, Shaochun
Jia, Suyue
Yang, Peng
Lu, Hongbin
Wu, Yang
Huang, Ye
Abstract
22 nano-scale phase change material is prepared by means of a sol-gel method in combination with a microemulsion method under alkaline conditions. The material prepared in the present application has a particle size of about 500 nm, a phase change temperature of 27.7ºC, a phase change latent heat of 159.74 J/g, and a thermal decomposition temperature that is 50ºC higher than the thermal decomposition temperature of n-octadecane.
Provided in the present disclosure are a memory unit, a storage method, a memory array, a memory and a manufacturing method therefor. The storage method uses at least one three-dimensional dynamic random access memory unit and comprises: applying a suitable voltage to a selected gate layer used for storing information, so that a charge coupling layer controlled by the gate layer carries out dynamic random storage of information, first and second doped type material layers writing and resetting involved information in collaboration with each other; applying a suitable voltage to a selected gate layer for reading, so as to alter the on-off capability of a signal reading layer controlled by the gate layer, thereby reading out a voltage or current related to the information as third and fourth doped type material layers respectively serve as a source and a drain of the signal reading layer; and performing information storage in such a way of stacking layer by layer in the vertical direction or partition by partition in the horizontal direction the information stored in a plurality of gate layers. The method provided by the present disclosure can separate writing paths from reading paths, and has the characteristics such as high storage density, high speed and low power consumption.
The disclosure relates to an activity recognition method of a large receptive field (LRF) large-kernel attention convolution network based on a large receptive field, the method includes the following steps: collecting an action signal, carrying out a preprocessing and a data partition on the action signal to obtain a data set; and training an LRF large-kernel attention convolution network model based on the data set, and introducing a trained LRF large-kernel attention convolution network model into a mobile wearable recognition device for human posture recognition.
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
50.
SILICA-ENCAPSULATED NANO-PHASE CHANGE MATERIAL AND PREPARATION METHOD THEREOF
HAIAN INSTITUTE OF HIGH-TECH RESEARCH, NANJING UNIVERSITY (China)
Inventor
Tang, Shaochun
Jia, Suyue
Yang, Peng
Lu, Hongbin
Wu, Yang
Huang, Ye
Abstract
A silica-encapsulated nano-phase change material and its preparation method are provided. An n-octadecane SiO2 nanoscale phase change material is prepared by sol-gel and microemulsion coupling under alkaline conditions using silica as the shell material and n-octadecane as the core material in a microcapsule and using ethyl n-silicate as the silica source, cetyltrimethylammonium bromide as the emulsifier, and water and ethanol as the solvents. The materials prepared have a particle size of about 500 nm, a phase transition temperature of 27.7° C., a latent heat of phase transition of 159.74 J/g, and an elevated thermal decomposition temperature of 50° C. increase compared with that of the existing n-octadecane.
CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE (China)
HUAZHONG AGRICULTURAL UNIVERSITY (China)
Inventor
Dong, Xianchi
Liu, Wen
Ding, Jianping
Shi, Yu
Xu, Shutong
Xu, Jianbo
Abstract
Provided are a protein comprising an amino acid sequence capable of binding to a substrate GPRP peptide fragment, a fibrinogen like protein 1 (FGL1) comprising the amino acid sequence, and a fibrinogen domain (FD) thereof, and an individual FD protein has the same or similar function as the FGL1. The FGL1 and the FD can inhibit the assembly of fibrin in a thrombogenesis process by competing for a fibrin substrate-binding pocket. By means of mutations, the FGL1 and the FD can have stronger substrate affinity, such that the using effect of a thrombus treatment drug can be effectively enhanced.
An optical phased array device, which can flexibly set the light splitting weight and has good scalability, includes a light splitting network, phase shifters, and emission units. Among them, the light splitting network of the device can set the optical power weight of the array element freely and has good scalability. The light splitting network of optical phased array consists of a series of basic elements, each of which can realize uniform or non-uniform light splitting of N channels. The light splitting network adopts a tree topology. The tree network structure can be freely designed, and the components used by the network nodes can also be freely selected. By freely designing the structure of the light splitting network and the components used by each node, the optical output distribution of the network can be set, so that the far field distribution of the optical phased array can be optimized.
G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
G02B 6/28 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
53.
METHOD FOR REGULATING THERMAL BOUNDARY CONDUCTANCE BETWEEN METAL AND INSULATOR
Provided is a method for regulating a thermal boundary conductance between a metal and an insulator, including: arranging a metal on a surface of an insulator, a contact surface between the metal and the insulator being a boundary between the metal and the insulator; and the insulator including a ferroelectric, a piezoelectric, or a pyroelectric; applying an external electric field or stress to the ferroelectric, and adjusting a magnitude of the external electric field or stress, or an included angle between a direction of the external electric field or stress with the boundary to regulate the thermal boundary conductance; or applying a stress to the piezoelectric, and adjusting a magnitude of the stress, or an included angle between a direction of the stress with the boundary to regulate the thermal boundary conductancer; or adjusting a temperature of the pyroelectric to regulate the thermal boundary conductance.
H01B 3/00 - Insulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties
H01B 1/02 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of metals or alloys
H01B 3/10 - Insulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of inorganic substances metallic oxides
H01B 13/00 - Apparatus or processes specially adapted for manufacturing conductors or cables
H01B 13/22 - SheathingArmouringScreeningApplying other protective layers
54.
RNA PLASMID DELIVERY SYSTEM AND APPLICATION THEREOF
Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
55.
VIRAL VECTOR-BASED RNA DELIVERY SYSTEM AND USE THEREOF
Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.
Disclosed are a TLR7-IFN I signaling pathway activated mouse in-vivo cell, a humanized systemic lupus erythematosus mouse having the cell, a construction method for the mouse, and a use of the mouse in medical research. Specifically, a TLR7-IFN I signaling pathway of a cell is activated by administering a TLR7 agonist Resiquimod, such that the mouse exhibits a similar phenotype of a patient with systemic lupus erythematosus, and a plasmid expressing human Flt3L and a DNA derived from autologous activated lymphocytes are injected into the mouse, such that the humoral immune response of B cells of the mouse is promoted, and B cell subpopulation imbalance and autoantibody generation are induced, thereby constructing the humanized systemic lupus erythematosus mouse. According to the humanized systemic lupus erythematosus mouse, immune disorders and corresponding phenotypes are induced in a human immune system, such that the humanized systemic lupus erythematosus mouse is more beneficial to screening a novel targeted drug.
Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
58.
RNA DELIVERY SYSTEM FOR TREATMENT OF HUNTINGTON'S DISEASE
An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 9/00 - Medicinal preparations characterised by special physical form
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
The present invention discloses a container equipment for enclosed transportation and heterotopic and aerobic stabilization of reserved garbage, which includes a container body and a functional lining provided on an inner wall of the container body, wherein the functional lining is provided with a circulating air low-temperature evaporation system, a water distribution and drainage system and a heating and insulating system; the circulating air low-temperature evaporation system includes an air inlet manifold, an air distribution perforated pipe, a base plate water discharge and air distribution groove and a top plate water distribution and air guide groove, an air extraction perforated pipe, a fan, an air outlet pipe and a quicklime dehydration and deodorization system; the water distribution and drainage system includes a percolate feeding pipe, a fiber capillary water distribution pipe, the top plate water distribution and air guide groove, a side drain, a main drain and a percolate discharge pipe; the heating and insulating system includes a base plate hydrothermal manifold, a bottom hydrothermal coil, a peripheral hydrothermal layer, a bottom air insulating layer and a peripheral air insulating layer. The present invention also discloses a method for using the container equipment described above. The present invention achieves a fully-enclosed transportation of solid waste and a heterotopic and aerobic stabilization process.
Provided in the present invention are a genetically modified mouse cell, a mouse having a humanized immune system containing said mouse cell, and a construction method for the humanized mouse. The method comprises: inactivating a GFI1 gene on a mouse, and without sublethal irradiation, directly carrying out a humanized modeling process by injecting hematopoietic stem cells, wherein the dosage of the hematopoietic stem cells can be reduced to one eighth of an original reference dose.
A structure of a two-dimensional material-based device having an air-gap and a method for preparing same comprises a substrate, a gate, an dielectric, a two-dimensional material-based film, and source and drain electrodes; the air-gap is formed between the two-dimensional material-based film and the side wall of the dielectric on the gate, or the air-gap is formed between the dielectric and the gate; two-dimensional material-based devices of the above structure utilize the ductility and flexibility of two-dimensional materials to reduce the coupling between the gate and the source/drain electrodes, thereby reducing the parasitic capacitance and the circuit delay; also, the structure ensures that a part of the contact region of the source and drain electrodes with the two-dimensional material can be controlled by the gate, and can thus avoid the reduction in electrical properties and keep a low resistance of the device.
A polycationic polysaccharide and an application thereof is disclosed. Specifically, the polycationic polysaccharide consists of a polysaccharide and a polyamine compound, and is a positively charged polycationic polysaccharide obtained by reacting a polysaccharide with an amine-containing or polyamine compound. The polycationic polysaccharide is applied in a biomedical functional material of an antibacterial biofilm, a biomedical device, and an antibacterial functional material.
C08L 5/00 - Compositions of polysaccharides or of their derivatives not provided for in group or
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
63.
Preparation method and application of clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics
QUANZHOU INSTITUTE FOR ENVIRONMENTAL PROTECTION INDUSTRY, NANJING UNIVERSITY (China)
Inventor
Yang, Hu
Chang, Qianqian
Abstract
A preparation method and an application of a clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics are provided, which relate to the field of water environment treatments. A clay/tannic acid/metal ion composite adsorbent is prepared, preparation method and operation process are simple, synthesis time is short, and yield is large. A raw material used is tannic acid, which has a wide range of sources, is non-toxic, biodegradable, and has no risk of secondary pollution, due to abundant phenolic hydroxyl groups in tannic acid, the tannic acid can not only chelate with the metal ions, but also adsorb pollutants from water, when combined with the clay and the metal ions, a composite body is formed, which has a rougher surface, and adsorption active sites are increased, thereby effectively increasing adsorption, and improving an adsorption performance for pollutants. The clay/tannic acid/metal ion composite adsorbent has good adsorption effect for antibiotics.
C02F 1/28 - Treatment of water, waste water, or sewage by sorption
B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
B01J 20/12 - Naturally occurring clays or bleaching earth
B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
B01J 20/30 - Processes for preparing, regenerating or reactivating
It is disclosed a method and system based on machine learning for reconstructing biological wastewater treatment processes; the method includes: acquiring influent and effluent basic quality, ecological risk and process information data on the biological wastewater treatment process, and performing data preprocessing; performing feature extraction and multi-unit characterization on the biological wastewater treatment process; constructing effluent basic quality prediction models and effluent ecological risk prediction models of different biological treatment multi-unit combination processes, and performing standard-reaching validation; simulating and reconstructing different biological wastewater treatment short-range unit combination processes, and performing effluent quality standard-reaching validation under different influent quality scenarios; and evaluating ecological risk of the reconstructed short-range biological treatment unit combination processes with the effluent quality up to standard, and determining the optimal biological wastewater treatment process.
The present disclosure discloses a method for modifying a DNA by utilizing a glycosylase and an oxyamine compound, including the following steps: conducting solid phase synthesis of a DNA strand carrying a non-canonical base; reacting the DNA strand carrying a non-canonical base under the catalysis of the glycosylase which selectively recognizes the non-canonical base, to produce a DNA strand carrying an abasic site; and reacting the DNA strand carrying the abasic site with the oxyamine compound to generate a DNA modified with a chemical functional group. This method can realize diverse site-directed modification of the DNA, can be used to study the base structure-function relationship of a functional DNA, and construct a functional DNA with higher activity. The present method is simple and easy to use, and can reduce the cost and the time required for modification. The modified functional DNA has higher activity and can provide better tool molecules for biotechnology, disease diagnosis and treatment.
Haian Institute of High-Tech Research, Nanjing University (China)
Inventor
Tang, Shaochun
Zhang, Rong
Xiang, Bo
Shen, Yuchun
Abstract
Disclosed is a method for preparing a three-dimensional porous nano composite cooling film in large scale. The cooling film is prepared from 0.1-0.5 parts of cellulose acetate, 1-5 parts of water, 20-100 parts of acetone, an additive, and 10-20 parts of nano microspheres through a cooperative formulation of cellulose acetate, nano microsphere materials and the additive. The composite cooling film is obtained by self-deposition of cellulose acetate and nano microspheres, and liquid volatilization during film forming process leads to formation of the three-dimensional porous structure. The film has an effect of enhancing radiation of infrared heat into space, which could significantly reduce a temperature of a substrate surface and achieve rapid and strong cooling. The film could achieve effective cooling without external power and other active cooling equipment, with or without sunlight.
C04B 26/28 - Polysaccharides or derivatives thereof
B29C 39/00 - Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressureApparatus therefor
C04B 20/00 - Use of materials as fillers for mortars, concrete or artificial stone according to more than one of groups and characterised by shape or grain distributionTreatment of materials according to more than one of the groups specially adapted to enhance their filling properties in mortars, concrete or artificial stoneExpanding or defibrillating materials
C04B 38/00 - Porous mortars, concrete, artificial stone or ceramic warePreparation thereof
C04B 40/00 - Processes, in general, for influencing or modifying the properties of mortars, concrete or artificial stone compositions, e.g. their setting or hardening ability
67.
PHOTORESIST-FREE OPTICAL PATTERNING METHOD FOR COLLOIDAL NANOCRYSTALS IN GREEN SOLVENT
The present invention relates to the technical field of nanomaterials and optical etching, and provides a photoresist-free optical patterning method for colloidal nanocrystals in a green solvent. A photosensitive ligand structurally similar to the green solvent is introduced to successfully disperse nanocrystals in the green solvent and perform photolithography directly on the nanocrystals. Photosensitive nanocrystals obtained through ligand exchange can be effectively dispersed in the green solvent to absorb an emission spectrum emitted by the green solvent, thereby preserving about 90% of photoluminescence quantum yield (PLQY) while keeping the morphology and size unchanged. The scheme solves the problem that nanocrystals cannot be subject to direct photolithography in the green solvent, and is expected to be applied to the commercialization of nanocrystals in the field of electroluminescent and photoluminescent quantum dot displays.
The present disclosure relates to a solar battery including a first cell, and a second cell, and a first charge transport layer, a transparent conductive layer, a second charge transport layer and a polysilicon layer are disposed between the first photoelectric conversion layer of the first cell and the second photoelectric conversion layer of the second cell, and the second charge transport layer is disposed between the polysilicon layer and the transparent conductive layer, and the charge transport property of the second charge transport layer is the same as that of the polysilicon layer. In the solar battery of the present disclosure, a first charge transport layer, a transparent conductive layer, a second charge transport layer and a polysilicon layer are sequentially arranged between the first photoelectric conversion layer and the second photoelectric conversion layer. Especially the second charge transport layer may protect the polysilicon layer, may effectively transport the same type of charges, and avoid recombination phenomena at the interface or inside the film, thereby effectively improving the efficiency of the battery. The solar battery of this disclosure also has the characteristics of simple structure, simple and convenient manufacturing process, and low cost.
H10K 30/57 - Photovoltaic [PV] devices comprising multiple junctions, e.g. tandem PV cells
H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
69.
DEVICE AND METHOD FOR PARALLELIZING ANALOG IN-MEMORY COMPUTING BASED ON FREQUENCY DIVISION MULTIPLEXING
A device for parallelizing analog in-memory computing based on frequency division multiplexing comprises an input circuit, a memory array and an output circuit, wherein an input of the memory array is connected with an output of the input circuit, and an output of the memory array is connected with an input of the output circuit; the input circuit modulates k data in each row of m×k input data matrix into each path of frequency division multiplexing signals for output by using k different frequency sources; the memory array comprises m×n memory elements, memory weights thereof form an m×n matrix, and m×1 input frequency division multiplexing signals are parallel-processed in the memory array; and the output circuit demodulates and separates each path of frequency division multiplexing signals output by the memory array into k data.
ECL-BASED ELECTRODE, MANUFACTURING METHOD FOR ECL-BASED ELECTRODE, ECL SENSOR, MANUFACTURING METHOD FOR ECL SENSOR, METHOD FOR ECL DETECTION OF NUCLEIC ACID-SPECIFIC SITE MODIFICATION, AND KIT FOR NUCLEIC ACID MODIFICATION DETECTION USED FOR METHOD FOR ECL DETECTION OF NUCLEIC ACID-SPECIFIC SITE MODIFICATION
A manufacturing method for an ECL (Electrochemiluminescence)-based electrode according to an embodiment includes a step of mixing an electrocatalytic solution and metal nanoparticles and thereafter dropping a mixed particle suspension onto the surface of an electrode and obtaining a base electrode co-modified by an electrocatalyst-metal nanoparticle.
G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
A distributed weak grating array sensing system and method with multiple demodulation modes are provided for optical fiber sensing. The distributed weak grating array sensing method includes: amplitude modulating, by an acousto-optic modulator, a laser light to form a double-pulse light satisfying a preset requirement; linearly phase modulating, by a phase modulator, a phase of front pulse light or rear pulse light of the double-pulse light; amplifying double-pulse light after amplitude modulation and phase modulation, and introducing the double-pulse light into a grating array; allowing reflected light of the double-pulse light on adjacent gratings to superimpose and form interference light; introducing the interference light into a photoelectric detector; acquiring, by an acquisition card, data; locating a disturbance through the amplitude fluctuation; accurately acquiring a sampling number corresponding to 2π; and selecting π/2 phase difference demodulation, 2π/3 phase difference demodulation, π/4 phase difference demodulation, proposed N-step phase difference demodulation as required.
G02F 1/11 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on acousto-optical elements, e.g. using variable diffraction by sound or like mechanical waves
G01H 9/00 - Measuring mechanical vibrations or ultrasonic, sonic or infrasonic waves by using radiation-sensitive means, e.g. optical means
72.
Method and system for intelligent source tracing of organic pollution of water body
Disclosed are a method and system for intelligent source tracing of organic pollution of a water body, which belongs to the technical field of environmental analytical chemistry. The method comprises: acquiring organic matter analysis and detection data from water samples of a polluted water body through high performance liquid chromatography-tandem mass spectrometry; performing high-throughput screening on the organic matter in the water samples according to said data to determine pollutants; identifying pollution sources by means of network analysis according to the determined pollutants; and according to the identified pollution sources and the organic pollutants, determining key pollutants and quantifying the pollution contributions thereof by using a machine learning classification model. The present invention can achieve intelligent tracing of the pollution sources and the key pollutants thereof in the case of the pollution sources being unknown, and provide technical support for investigation and control of organic pollution in a water environment.
An interfacial adsorption method for efficiently enriching perfluorinated compounds in a water body, the interfacial adsorption method comprising the steps of: mixing a polluted water body containing a perfluorinated compound, a long-carbon-chain cationic surfactant and a water-insoluble oil substance to obtain an oil-water mixture of an oil phase and a water phase, which mixture contains the perfluorinated compound and the cationic surfactant; and leaving the oil-water mixture to stand for adsorption. By introducing a long-carbon-chain cationic surfactant onto an oil-water interface, the cationic surfactant is tightly combined with an anionic perfluorinated compound by means of electrostatic interaction, such that an active interface with an electron attracting capability is constructed, and efficient enrichment and removal of the perfluorinated compound on the interface are realized.
An identification method of urban functional areas based on mixing degree of functions and integrated learning includes the following steps: 1) performing data acquisition and preprocessing; 2) constructing 10 indicator features of an urban functional area identification system; 3) structuring the indicator features: acquiring, by a spatial statistical tool, the 10 indicator features corresponding to each parcel; 4) constructing an independent variable dataset; 5) labeling response variables; 6) dividing a training dataset into a plurality of training subsets according to the mixing degree of functions; 7) training a Stacking-based integrated learning model; and 8) joining an attribute in one table to another table, so as to complete the identification of the urban functional areas on each parcel. The identification method divides the training dataset by grading the mixing degree of functions, and makes predictions based on the prediction dataset with corresponding mixing degree of functions.
An artificial board and a preparation method therefor. The preparation method comprises the following steps: activating plant fibers with a non-derivatized solvent to obtain a plant fiber solution, wherein the plant fibers are wall-broken or non-wall-broken plant cells; then mixing the plant fiber solution with plant particles until uniform, and molding same; and then subsequently subjecting same to a drying treatment, a soaking and cleaning treatment and a standing treatment, so as to obtain an artificial board. In the method, plant particles and activated plant fibers are cross-linked by means of hydrogen bonds to prepare an artificial board, a resin adhesive does not need to be used, and toxicity and harm are avoided during the production and use processes. Moreover, since a large number of hydroxyl groups are exposed after the plant fibers in the plant fiber solution are subjected to an activating treatment, stronger cross-linking between the plant fibers and the plant particles are more easily realized, and therefore the artificial board is endowed with good mechanical properties.
A three-dimensional (3D) reconstruction device and a method of flame spectra are provided. The device has a plurality of prism-mask shooting systems and a plurality of mirrors. The prism-type shooting systems are set up around a combustion area to be reconstructed and each is provided with two mirrors which are tilted on the left and right of an axis of the shooting system, so that data of a flame are reflected by the mirrors into the prism-mask shooting systems, thus realizing the real-time acquisition of hyperspectral data of the flame from multiple shooting angles. The reconstruction method includes following steps of acquiring, by a calibration cylinder, an area to be reconstructed, synchronously acquiring and preprocessing hyperspectral data of a flame, and finally reconstructing 3D spectral data of the flame by a 3D reconstruction algorithm of flame spectra.
A rice production potential simulation method based on land system and climate change coupling, the method comprising the following steps: constructing a GM-FLUS model to simulate a change of a land system (S1); using a GAEZ model to estimate rice production potential (S2); and analyzing spatial distribution features and time change trends of the rice production potential in different scenarios (S3). By means of constructing a GM-FLUS model to simulate a change of a land system, in view of four future climate scenarios of SSP1-2.6, SSP2-4.5, SSP3-7.0 and SSP5-8.5 among shared socioeconomic pathways (SSPs) under a CAS-ESM2 climate scenario model intercomparison project, and by using a GAEZ model to take various factors such as climate, soil, terrain, a land system, etc., into consideration, rice production potential is estimated, thereby providing a technical support for coping with a future climate change, rationally using cultivated land resources and guaranteeing food security.
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
A porous aminated organic fluorine capsule, a preparation method therefor and a use thereof. The porous aminated organic fluorine capsule comprises a porous organic fluorine shell, and an aminated phenolic resin is filled in the organic fluorine shell. On the basis of a common polyvinylidene fluoride membrane material, a polyvinylpyrrolidone pore-forming agent, and the aminated phenolic resin, a porous organic fluorine capsule material is synthesized by a solvent displacement method; under a synergistic effect of the organic fluorine shell of the capsule and the internal aminated phenolic resin, efficient and selective removal of an anionic perfluorinated compound is successfully achieved; and moreover, the raw materials are cheap and readily available, and the preparation is simple and convenient.
A system and a method for characterizing a target analyte are provided. The system comprises a nanopore and a polymer strand comprising a tether site and a reaction section, wherein the polymer strand is tethered via the tether site so that the polymer strand cannot pass through the nanopore, and wherein the reaction section comprises at least one sensing module which can interact with single molecule of the target analyte.
NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES, MEE (China)
NANJING UNIVERSITY (China)
Inventor
Guo, Xinyan
Wang, Na
Yuan, Qingbin
Ni, Ni
Zhang, Xiaohui
Shi, Mali
Li, Jingbiao
Abstract
A method for assessing microbial drug resistance multi-level risks of antibiotic residues in water environments, belonging to the technical field of water environment assessment, comprises the following steps: S1, environment monitoring; S2, preliminary screening of antibiotics: S2-1, determination of n-octanol/water partition coefficient, and S2-2, determination of antibiotic environment concentration; S3, assessment of microbial drug resistance; and S4, high-level assessment. The assessment method of the present disclosure conducts a step-by-step assessment of target antibiotics or target antibiotic derivatives in water environment with risks.
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
81.
DEVICE FOR SYNTHESIZING HOMOGENEOUS POLYMER SPHERES BASED ON CHANNEL PREPOLYMERIZATION, AND METHOD OF USING THE SAME
A homogeneous polymer sphere synthesis device based on channel prepolymerization comprises a jet vibrator, a spiral prepolymerization channel, a reactor and a water phase circulating system; two ends of the water phase circulating system are connected to the reactor and the spiral prepolymerization channel through pipes, respectively; the jet vibrator comprises a jet oil phase tank, a jet micropore plate and a vibration exciter for outputting vibration; the jet micropore plate is arranged in the jet oil phase tank; an outlet end of the spiral prepolymerization channel is connected to the reactor, while an inlet end thereof is connected to the jet oil phase tank.
ELECTROCHEMILUMINESCENT NANOPROBE, PREPARATION METHOD THEREOF, ELECTROCHEMILUMINESCENCE DETECTION METHOD FOR NUCLEIC ACID SPECIFIC SITE MODIFICATION, KIT FOR ELECTROCHEMILUMINESCENCE DETECTION METHOD USING ANTIBODY, AND NANOPARTICLE FOR ELECTROCHEMILUMINESCENT NANOPROBE
A method for preparing an electrochemiluminescent nanoprobe according to an embodiment includes: adding a metal complex ion to an inorganic oxide nanoparticle to provide a metal-doped inorganic oxide nanoparticle; and binding a secondary antibody to the metal-doped inorganic oxide nanoparticle to provide a metal-doped inorganic oxide nanoparticle modified with the secondary antibody. The secondary antibody is configured to identify a specific antibody against nucleic acid-specific site modification.
The present invention relates to the field of water sample pretreatment apparatuses. Disclosed are a low-carbon and high-efficiency in-situ rapid enrichment and separation apparatus and method for a large-volume water sample. According to the present invention, by means of optimization of the shape structure of the apparatus in combination with dynamic collection of magnetic materials, a static settling process is eliminated, so that the problems that the magnetic materials are slow in settling velocity and prone to loss are solved, and the enrichment and separation efficiency of the magnetic materials is improved; moreover, such a low-carbon and energy-consumption-free operation mode has important application prospects in sampling processes in the field, especially in remote areas.
C02F 1/26 - Treatment of water, waste water, or sewage by extraction
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
84.
PHOTOCATALYTIC MATERIAL FOR DEGRADING PYRIDINE, MODIFIED PHOTOCATALYTIC FILLER, AND PREPARATION METHODS THEREFOR AND USE THEREOF
344344 photocatalytic material, wherein the gradient hydrothermal reaction comprises: heating same to 155-165°C, maintaining the temperature for at least 2 h, heating same to 175-185°C, maintaining the temperature for at least 8 h, finally heating same to 210-230°C, and maintaining the temperature for at least 2 h, the heating rate being 1-3°C/min. In the present invention, the photocatalytic performance and recyclability of bismuth vanadate can be effectively improved, and when a porous filler is coated with bismuth vanadate, pyridine having concentrations of 100 mg/L and 500 mg/L can be completely mineralized and removed within 24 hours and 48 h, respectively.
2332x32xx-MXene with an iron ion salt and an organic ligand for a reaction, wherein the organic ligand can be coordinated with Fe3+233-MXene composite catalyst. In the present invention, the problems of ferric oxide prepared by a traditional method being prone to agglomeration and having a poor electron transfer performance and a poor stability are solved, tetracycline in persulfate degradation wastewater can be fully activated, and the method has the advantages of a high efficiency, a high use value, ease of catalyst recovery, etc., and has great application prospects.
A Fenton-like catalyst material with an electron-poor Cu center and a preparation method and use thereof are provided. The preparation method includes: step 1: dissolving bismuth nitrate pentahydrate in a nitric acid solution and diluting a resulting solution with deionized water to obtain a solution A; step 2: adding citric acid to the solution A and adjusting a pH of a resulting solution with ammonia water to obtain a solution B; step 3: dissolving aluminium isopropoxide (AIP), copper chloride dihydrate, and glucose in the solution B to obtain a suspension C; step 4: stirring the suspension C at a high temperature to allow evaporation until a solid D is completely precipitated; and step 5: subjecting the solid D to calcination in a muffle furnace to obtain the Fenton-like catalyst material. Under neutral conditions, the catalyst material exhibits a prominent removal effect for various toxic organic pollutants, especially for phenolic pollutants.
NANJING UNIVERSITY & YANCHENG ACADEMY OF ENVIRONMENTAL PROTECTION TECHNOLOGY AND ENGINEERING (China)
Inventor
Wang, Jinnan
Hou, Zhiang
Bian, Weilin
Wang, Yi
Chu, Jiangfeng
Liu, Cong
Abstract
A photocatalytic material for efficient photocatalytic removal of a high-concentration nitrate, and a preparation method and use thereof are disclosed. The preparation method includes the following steps: step 1: preparation of a citrate-stabilized silver nanoparticle; step 2: synthesis and functionalization modification of SiO2 step 3: preparation of Ag/SiO2; and step 4: preparation of an Ag/SiO2@cTiO2 core-shell structure. The photocatalytic material prepared by the present disclosure has high reduction catalytic activity and can quickly remove a high-concentration nitrate and achieve high nitrogen selectivity. In addition, due to protection of a titanium dioxide shell, the photocatalytic material has excellent stability and can remove a high-concentration nitrate in water when the nitrate coexists with a high-concentration chloride ion.
Disclosed are a time delay integration (TDI)-based image sensor and an imaging method thereof. The TDI-based image sensor includes: a multi-stage linear array including a plurality of single-stage linear arrays arranged along a scanning direction of the image sensor. Each single-stage linear array includes a plurality of pixels arranged along the linear array direction. Each single-stage linear array enters a count mode in response to a first control signal, and enters a transfer mode in response to a second control signal. In the count mode, each single-stage linear array counts optical signals incident on the pixels and obtains a count value, and in the transfer mode, each single-stage linear array stops counting, except for the last single-stage linear array, other single-stage linear arrays each output the obtained current count value to the next single-stage linear array, and the last single-stage linear array outputs the obtained current count value.
LISHUI INSTITUTE OF ECOLOGICAL ENVIRONMENT, NANJING UNIVERSITY (China)
Inventor
Yuan, Zengwei
Cheng, Mingjin
Cheng, Xiang
Zhang, Shiwen
Abstract
Provided in the present application is a process method for full-scale resource utilization of kitchen waste using Hermetia illucens and aerobic microorganisms. The method comprises: firstly, performing solid-liquid separation on kitchen waste; then performing quality-based resource utilization on the separated filtrate containing oils and salts and kitchen waste filter residues, and feeding young Hermetia illucens and 2nd-6th instar Hermetia illucens larvae respectively, so that the salts in the filtrate are transformed into the body fluid of the Hermetia illucens at the larval stage; separating the larval bodies and the larval residues in a timely manner so as to reduce the salinity of the larval feces and improve the transabdominal transformation efficiency of Hermetia illucens and the quality of the larval feces as a fertilizer; and finally, achieving the full-scale resource utilization of kitchen waste by means of aerobic composting and the dry sterilization of the larval bodies. According to the present invention, by synergistically utilizing the principles of transabdominal transformation by Hermetia illucens and degradation by aerobic microorganisms for the first time, the full-scale resource utilization of kitchen waste is achieved, and the problems of the high-salt wastewater in the existing transformation process being difficult to treat, the salt content of a fertilizer being too high to be used as a resource, and the nitrogen loss in the transformation process being severe are overcome.
LISHUI INSTITUTE OF ECOLOGICAL ENVIRONMENT, NANJING UNIVERSITY (China)
Inventor
Yuan, Zengwei
Cheng, Mingjin
Cheng, Xiang
Zhang, Shiwen
Abstract
Hermetia illucens L. and quality of the insect manure; and finally implementing full resource utilization through aerobic composting and insect drying and sterilization treatment.
A self-heterodyne phase-sensitive optical time domain reflectometry (φ-OTDR) system with a free multi-spatial resolution includes a narrow linewidth laser source, a 1×3 fiber-optic coupler, three acousto-optic modulators (AGMs), a 3×1 fiber-optic coupler, two time-delay fibers, an erbium-doped fiber amplifier (EDFA), a circulator, a photodetector, an electrical amplifier, three filters, a data acquisition card, a pulse signal generator, and a driver module. A plurality of acousto-optic modulators using the same driver are used to couple probe light with different pulse intervals and different frequency shifts and then inject the probe light into a fiber, such that a self-heterodyne detection structure with a multi-spatial resolution is implemented, which suppressed optical background noise such as coherent fading noise, phase noise introduced by a frequency drift of a light source, and pseudo-random noise (PRN).
G01D 5/353 - Mechanical means for transferring the output of a sensing memberMeans for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for convertingTransducers not specially adapted for a specific variable using optical means, i.e. using infrared, visible or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells influencing the transmission properties of an optical fibre
92.
Method for removing chlorinated hydrocarbons in groundwater through step-by-step electrocatalytic dechlorination degradation
The present disclosure discloses a method for removing chlorinated hydrocarbons in groundwater through step-by-step electrocatalytic dechlorination degradation. A double-chamber electrolyzer reactor is used to carry out step-by-step electrocatalytic dechlorination degradation to remove chlorinated hydrocarbons in groundwater. The double-chamber electrolyzer reactor comprises a cathode chamber, a proton exchange membrane, an anode chamber and an intermediate processing unit, wherein the cathode chamber is separated from the anode chamber through the proton exchange membrane, and the intermediate processing unit is connected between the cathode chamber and the anode chamber through a cathode chamber water outlet, an anode chamber water inlet and pipelines. The double-chamber electrolyzer reactor adopted in the present disclosure is simple in structure and convenient to use, is capable of effectively enhancing the removal effect of electric catalysis on chlorinated hydrocarbon substances and reducing toxic and harmful substances produced by direct oxidization of chlorinated hydrocarbons, and has a good application prospect.
A model training method and a related device, which are applied to the technical field of artificial intelligence, and by means of which a trained model that is obtained by the joint training of a client and a server can have a sufficiently good function. The model training method comprises: when a server needs to acquire a neural network model having a data processing function, the server can issue a model to be trained to a client, wherein each neuron of a plurality of neurons in said model has a parameter and a location code; after receiving said model, the client can use local data stored therein as training data, and input same into said model, so as to process the training data by means of the parameters and location codes of the plurality of neurons in said model, thereby updating said model to obtain an updated model; and then, the client can send the updated model to the server, so that the server can perform aggregation on the basis of the updated model which is uploaded by the client, so as to obtain a trained model.
A method for removing periodic noise from a reconstructed light field image includes the steps of: acquiring a light field image of a sample; acquiring an optical center position map without the sample; calibrating the imaging centers of the microlenses and performing reconstruction on the light field image; transforming a reconstructed light field image to the frequency domain and generating an image frequency spectrum; preprocessing the image frequency spectrum; generating a low-pass filter; multiplying the low-pass filter with the preprocessed image frequency spectrum, and then setting the frequency spectrum value of the low-frequency component to zero; performing binarization on the reconstructed light field image frequency spectrum to obtain an image mask; removing the high-frequency periodic noise component from the original frequency spectrum of the reconstructed light field image; and transforming the filtered reconstructed light field image frequency spectrum back to the spatial domain to obtain the reconstructed light field image.
The present disclosure provides a system which enables exogenous probiotics to form a stable microenvironment in a host, can be applied by simple means such as oral administration, can achieve the effect of changing the composition of intestinal microbiota, and eventually plays a positive role in the treatment of malignant tumors.
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 11/00 - Drugs for disorders of the respiratory system
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Disclosed in the present invention a digital-asset confirmation method based on a hash algorithm, and a digital asset tracing method based on a hash algorithm. Participants during digital-asset confirmation comprise an original user, a certificate authority (CA) and a digital-asset authentication center. A confirmation process involves: the original user generating a disposable CA certificate; the digital-asset authentication center performing digital-asset authentication with the original user; the original user generating a confirmation file; the original user, the CA and the digital-asset authentication center making quantum digital signatures, etc. The tracing method comprises: generating an attachment file in real time, constructing a digital-assert unique identity at an access moment, performing traceability analysis, etc. By means of the present invention, a digital asset and the identity of an original user are confirmed, and the security of confirmation is improved to a quantum security level. In addition, according to the solution in the present invention, a digital asset in the Internet of value passes authentication, and then has a real-time unique identity, such that forward tracing can be performed by means of the real-time unique identity of the digital asset, thereby completing the tracing analysis of the digital asset.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
The present invention discloses a design for reducing a dark count rate of a superconducting nanowire single photon detector (SNSPD) based on a two-wire structure, which includes: intertwining two niobium nitride nanowires that are not crossed to form an SNSPD of a two-wire structure; regulating and controlling behaviors of one nanowire by adopting the other nanowire, and regulating bias current to be close to superconducting critical current; introducing an optical signal into a photosensitive area of the detector by adopting an optical fiber; outputting two channels of signals respectively through the two nanowires to make the dark count rates of the two nanowires mutually excited; and through a voltage comparator and an exclusive-OR gate, reducing a dark count rate signal, and retaining a photon response signal. The generation of the dark count rate of the detector can be inhibited effectively by the unique performance of the SNSPD of the two-wire structure; and by improving the process latter, the coupling efficiency of the dark count rate of the SNSPD is further improved, which is expected to completely inhibit the dark count rate of the SNSPD system and greatly increase the signal-to-noise ratio of the detector.
x film (2). A traditional metal oxide type hydrogen sensor and a quantum conductance-based hydrogen sensor are combined on a flexible polymer substrate by means of an atomic layer deposition (ALD) technology and a cluster beam deposition (CBD) technology, so as to obtain a flexible hydrogen sensor with ultra-high sensitivity, a wide range and excellent selectivity and lower working temperature.
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
C23C 16/455 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for introducing gases into the reaction chamber or for modifying gas flows in the reaction chamber
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
99.
STRUCTURED SUPERCONDUCTING-TAPE SINGLE PHOTON DETECTOR AND PREPARATION METHOD THEREFOR
Disclosed in the present invention is a structured superconducting-tape single photon detector. In the present invention, the photon response sensitivity of a superconducting tape is improved by means of structure regulation and control, and the requirements of a conventional superconducting single photon detector regarding the width of a superconducting tape are reduced, such that high-sensitivity single-photon detection can be realized; and the structured superconducting-tape single photon detector is characterized in having a large detection area and a high speed, being simple in terms of preparation, being easily expandable to a large-scale array structure, etc. The single photon detector sequentially comprises, from bottom to top: a substrate, a structured superconducting tape, an electrode, an optical dielectric layer and an optical reflection layer. The preparation method mainly comprises: depositing a superconducting thin film on a surface of a substrate by means of magnetron sputtering; preparing a metal electrode on the superconducting thin film by means of photolithography and stripping technology; preparing on the superconducting thin film a structured superconducting tape shape by means of electron beam lithography technology and reactive ion etching technology; and respectively depositing an optical dielectric layer and a metal reflection layer on the surface of the structured superconducting tape by means of chemical vapor deposition technology and electron beam evaporation technology, which optical dielectric layer and metal reflection layer serve as optical cavities.
An MPCVD device capable of realizing effective doping, comprises a reaction chamber and a gas input structure, wherein the gas input structure includes a first pipeline and a second pipeline for reaction gas, a first gas distributor, connected with the first pipeline, uniformly transports gas as a first reactant into the reaction chamber through a gas outlet of the first pipeline located near the top of the reaction chamber, the second pipeline uniformly inputs a doped reaction gas to a surface of a substrate through a second gas distributor with circular shape, a height of the gas transport ring connected with the second pipeline is substantially the same as that of a support for the substrate, and the gas transport ring can be concentrically placed at a center position inside the support, or the gas transport ring can also be concentrically placed outside the support.
C23C 16/455 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for introducing gases into the reaction chamber or for modifying gas flows in the reaction chamber
C23C 16/458 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for supporting substrates in the reaction chamber
C23C 16/511 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using microwave discharges
