Nanjing University

Chine

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Type PI
        Brevet 690
        Marque 5
Juridiction
        International 439
        États-Unis 253
        Canada 3
Date
Nouveautés (dernières 4 semaines) 4
2025 février (MACJ) 3
2025 janvier 2
2024 décembre 4
2024 novembre 4
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Classe IPC
C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption 35
A61P 35/00 - Agents anticancéreux 31
C02F 1/72 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par oxydation 24
C02F 1/42 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par échange d'ions 19
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens 19
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Classe NICE
16 - Papier, carton et produits en ces matières 5
41 - Éducation, divertissements, activités sportives et culturelles 5
42 - Services scientifiques, technologiques et industriels, recherche et conception 5
Statut
En Instance 82
Enregistré / En vigueur 613
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1.

GEOGRAPHIC POSITION-BASED HIGH-SPEED RAIL MOBILE COMMUNICATION 6G FULLY-DECOUPLED NETWORK UPLINK TRANSMISSION METHOD AND SYSTEM

      
Numéro d'application CN2024108403
Numéro de publication 2025/036145
Statut Délivré - en vigueur
Date de dépôt 2024-07-30
Date de publication 2025-02-20
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Haibo
  • Sun, Zeyu
  • Xu, Yunting
  • Yu, Quan

Abrégé

Disclosed in the present invention are a geographic position-based high-speed rail mobile communication 6G fully-decoupled network uplink transmission method and system. The method comprises: according to geographic positions of a train and each uplink base station, performing line-of-sight channel mapping, so as to serve as channel estimation to carry out a secondary combining joint reception processing of the uplink signals; designing a deep learning neural network, taking the mapped line-of-sight channel as an input, and outputting a multi-user joint precoding that meets constraint conditions; performing offline training on a network by using historical channel data of each position; in an actual deployment stage, inputting a line-of-sight channel corresponding to the train position, the network outputting a joint precoding at the corresponding position, so as to achieve transmission without feedback. Compared with a traditional precoding design solution, the present invention solves the problem in a high-speed rail scenario of untimely channel feedback and large resource overhead due to high-speed movement, improves the frequency effect of wireless communication in a high-speed rail scenario, and provides an effective uplink transmission method for future high-speed rail mobile communications.

Classes IPC  ?

  • H04B 7/0456 - Sélection de matrices de pré-codage ou de livres de codes, p. ex. utilisant des matrices pour pondérer des antennes

2.

METHOD FOR REDUCING CONCENTRATION OF MICROORGANISM-DERIVED DISSOLVED ORGANIC NITROGEN IN WASTEWATER

      
Numéro d'application 18890980
Statut En instance
Date de dépôt 2024-09-20
Date de la première publication 2025-02-06
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Hu, Haidong
  • Liao, Kewei
  • Ren, Hongqiang

Abrégé

A method for reducing mDON concentration in wastewater, including a) acquiring a kinetics associated with production and consumption of a mDON of an activated sludge system, and importing a kinetic expression of the mDON into a conventional activated sludge model No. 1 (ASM1) to build a kinetic equation for the mDON; b) inputting component variables, parameter variables, model matrices, process rate equation and operating parameters of a predictive model into a simulation software to build an ASM-mDON model; c) inputting initial values of the component variables and the parameter variables into the simulation software for model initialization; d) acquiring initial mDON kinetic and sensitivity analysis results, selecting corresponding parameters, calibrating kinetic and stoichiometric parameters of the ASM-mDON model using a parameter estimation function of the simulation software; and e) replacing the initial values of the ASM-mDON model with optimal values obtained in d).

Classes IPC  ?

  • C02F 3/00 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout
  • C02F 1/44 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par dialyse, osmose ou osmose inverse
  • C02F 3/12 - Procédés par les boues activées
  • C02F 101/38 - Composés organiques contenant de l'azote

3.

ANTI-OUABAIN NANOBODY AND USE THEREOF

      
Numéro d'application CN2024108109
Numéro de publication 2025/026264
Statut Délivré - en vigueur
Date de dépôt 2024-07-29
Date de publication 2025-02-06
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yin, Wu
  • Xu, Chenming
  • Li, Hengda
  • Jin, Tong

Abrégé

The present invention belongs to the technical field of nanobodies, and specifically relates to an anti-ouabain nanobody and the use thereof. The amino acid sequence of the anti-ouabain nanobody is as shown in SEQ ID NO. 1. The nucleotide sequence thereof is as shown in SEQ ID NO. 2. The antibody has a good affinity to ouabain, can neutralize and antagonize the pharmacological activity of ouabain, and can be used to detect the content of ouabain in a solution in combination with an ELISA method. The present invention provides a method for constructing an ouabain antibody having a light weight, a high thermostability and a high detection sensitivity, and provides a research tool for deeply exploring the new biological functions of endogenous ouabain.

Classes IPC  ?

  • C07K 16/44 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel non prévu ailleurs
  • C07K 1/22 - Chromatographie d'affinité ou techniques analogues basées sur des procédés d'absorption sélective
  • C07K 1/18 - Chromatographie d'échange d'ions
  • C12N 15/13 - Immunoglobulines

4.

DOUBLE-ACID CATALYST AND METHOD FOR PREPARING FURFURAL BY CATALYZING HEMICELLULOSE OR XYLOSE

      
Numéro d'application CN2024095618
Numéro de publication 2025/020679
Statut Délivré - en vigueur
Date de dépôt 2024-05-27
Date de publication 2025-01-30
Propriétaire
  • ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD. (Chine)
  • NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wu, Youting
  • Li, Mian
  • Xu, Guangzhi
  • Liao, Chengjun
  • Hu, Changhui
  • Hu, Xingbang
  • Cheng, Xinping
  • Tu, Zhuoheng
  • Chen, Deshui

Abrégé

The present invention relates to a double-acid catalyst and a method for preparing furfural by catalyzing hemicellulose or xylose. The double-acid catalyst comprises choline chloride, a Bronsted acid, and a Lewis acid at a molar ratio of 1:1:1-4, and is in a deep eutectic state. The method comprises the following steps: adding into a reaction kettle a hemicellulose or xylose raw material, and the double-acid catalyst as a water phase, then adding an oil phase extraction agent, and carrying out catalytic dehydration and hydrolysis reactions in the reaction kettle to generate furfural, wherein the oil phase extraction agent continuously extracts the furfural from the water phase in the reaction process until the reaction is finished. According to the present invention, the choline chloride is combined with the Lewis acid and the Bronsted acid to form a deep eutectic solvent as the double-acid catalyst, and the deep eutectic solvent is used in the process of preparing furfural by catalyzing hemicellulose or xylose, thereby reducing the activation energy required by the reaction, and increasing the yield of the furfural. In addition, the water phase and the catalyst in the preparation process can both be recycled, thereby reducing the energy consumption and the production cost.

Classes IPC  ?

  • B01J 31/34 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant en outre des composés métalliques inorganiques non prévus dans les groupes du chrome, du molybdène ou du tungstène
  • C07D 307/48 - Furfural

5.

METHOD FOR ACCURATELY CONTROLLING DISSOLVED OXYGEN OF AEROBIC WASTEWATER TREATMENT SYSTEM

      
Numéro d'application 18790713
Statut En instance
Date de dépôt 2024-07-31
Date de la première publication 2025-01-09
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Ye, Lin
  • Ma, Yanyan

Abrégé

The present invention belongs to the technical field of wastewater treatment and more specifically relates to a method for accurately controlling dissolved oxygen of an aerobic wastewater treatment system. The system integrates the functions of online monitoring and dissolved oxygen control of system parameters of a wastewater treatment plant, can acquire data of the dissolved oxygen concentration, openings of air valves, air quantity of a fan, influent quality and quantity of the wastewater treatment system in real time, automatically calculates ideal values of the air quantity of the fan and the openings of the air valves according to a target value of the dissolved oxygen concentration by a server, screens an optimal adjusting mode on the basis of a certain condition, and finally sends an instruction to the fan or the air valves to realize the accurate control of dissolved oxygen of the wastewater treatment system.

Classes IPC  ?

6.

METHOD FOR PRODUCING ELECTROCHEMILUMINESCENCE NANOPROBE, ELECTROCHEMILUMINESCENCE NANOPROBE, ELECTROCHEMILUMINESCENCE SENSOR, ELECTROCHEMILUMINESCENCE DETECTION METHOD, AND KIT FOR ELECTROCHEMILUMINESCENCE DETECTION

      
Numéro d'application 18738909
Statut En instance
Date de dépôt 2024-06-10
Date de la première publication 2024-12-26
Propriétaire
  • CANON MEDICAL SYSTEMS CORPORATION (Japon)
  • Nanjing University (Chine)
Inventeur(s)
  • Wu, Xiaotian
  • Xu, Qiqi
  • Huang, Hao
  • Wang, Chao
  • Ju, Huangxian
  • Wu, Jie

Abrégé

A method for producing an electrochemiluminescence nanoprobe according to an embodiment includes: a hot exciton nanoparticle synthesis step of polymerizing a hot exciton organic luminescent molecule and a copolymer molecule to synthesize hot exciton nanoparticles; and a hot exciton nanoparticle modification step of modifying the obtained hot exciton nanoparticles with an oligonucleotide chain modified with a quencher molecule to obtain modified hot exciton nanoparticles.

Classes IPC  ?

  • C09K 11/07 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes ayant des constituants réagissant chimiquement entre eux, p. ex. compositions chimi-luminescentes réactives
  • C08F 8/34 - Introduction d'atomes de soufre ou de groupes contenant du soufre
  • C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
  • G01N 21/76 - ChimioluminescenceBioluminescence

7.

SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE

      
Numéro d'application 18698631
Statut En instance
Date de dépôt 2022-10-09
Date de la première publication 2024-12-19
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Huang, Shuo
  • Zhang, Shan Yu
  • Wang, Kefan
  • Wang, Yuqin
  • Liu, Yao

Abrégé

A protein nanopore comprising one or more sensing module and a method for characterizing a target molecule using the protein nanopore.

Classes IPC  ?

  • G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
  • G01N 33/84 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des composés inorganiques ou le pH

8.

ALTERNATING ELECTRIC FIELD-DRIVEN GALLIUM NITRIDE (GAN)-BASED NANO-LIGHT-EMITTING DIODE (NANOLED) STRUCTURE WITH ELECTRIC FIELD ENHANCEMENT EFFECT

      
Numéro d'application 18680824
Statut En instance
Date de dépôt 2024-05-31
Date de la première publication 2024-12-05
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Tao, Tao
  • Zhao, Rui
  • Zhi, Ting
  • Yan, Yu
  • Xie, Zili
  • Liu, Bin

Abrégé

An alternating electric field-driven gallium nitride (GaN)-based nano-light-emitting diode (nanoLED) structure with an electric field enhancement effect is provided. The GaN-based nanoLED structure forms a nanopillar structure that runs through an indium tin oxide (ITO) layer, a p-type GaN layer, a multiple quantum well (MQW) active layer and an n-type GaN layer and reaches a GaN buffer layer; and the nanopillar structure has a cross-sectional area that is smallest at the MQW active layer and gradually increases towards two ends of a nanopillar, forming a pillar structure with a thin middle and two thick ends. The shape of the GaN-based nanopillar improves the electric field strength within the QW layer in the alternating electric field environment and increases the current density in the QW region of the nanopillar structure under current driving, forming strong electric field gain and current gain, thereby improving the luminous efficiency of the device.

Classes IPC  ?

  • H01L 33/08 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une pluralité de régions électroluminescentes, p.ex. couche électroluminescente discontinue latéralement ou région photoluminescente intégrée au sein du corps semi-conducteur
  • H01L 33/00 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails
  • H01L 33/02 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs
  • H01L 33/06 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure à effet quantique ou un superréseau, p.ex. jonction tunnel au sein de la région électroluminescente, p.ex. structure de confinement quantique ou barrière tunnel
  • H01L 33/12 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure de relaxation des contraintes, p.ex. couche tampon
  • H01L 33/24 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué de la région électroluminescente, p.ex. jonction du type non planaire
  • H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote
  • H01L 33/42 - Matériaux transparents

9.

POLY(CARBAZOLE PHOSPHONIC ACID) MATERIAL, PREPARATION METHOD, AND USE IN PHOTOELECTRIC DEVICE

      
Numéro d'application CN2024096042
Numéro de publication 2024/245279
Statut Délivré - en vigueur
Date de dépôt 2024-05-29
Date de publication 2024-12-05
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s) Chen, Shangshang

Abrégé

The present invention relates to the field of material preparation. Disclosed are a poly(carbazole phosphonic acid) material and a preparation method therefor and a use thereof. The poly(carbazole phosphonic acid) material provided by the present invention has better stability, and the good film-forming property of the said material and the interaction between macromolecular chains can effectively solve the problems of poor compactness, easy diffusion and the like of traditional carbazole phosphonic acid small molecules, thereby producing a stable photoelectric device based on poly(carbazole phosphonic acid). The synthesis method for poly(carbazole phosphonic acid) is simple and rapid and involves mild reaction conditions. An obtained poly(carbazole phosphonic acid) material is dissolved in methylbenzene, chlorobenzene, chloroform, dichloromethane, methanol, ethanol, isopropanol and other single or mixed solvents, and is processed into thin films by means of processes such as spin coating, blade coating, slit coating, dip coating, spraying, and then a photoelectric device based on the poly(carbazole phosphonic acid) material is prepared. The present application has important scientific significance and an extremely high industrial value.

Classes IPC  ?

  • C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
  • H10K 85/10 - Polymères ou oligomères organiques
  • H10K 30/20 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des jonctions organiques-organiques, p. ex. des jonctions donneur-accepteur

10.

SYNTHESIS METHOD FOR LAYERED BIMETAL-BASED NANO LANTHANUM MATERIAL THAT SYNCHRONOUSLY LOCKS PHOSPHORUS, REMOVES ALGAE AND REDUCES TURBIDITY, AND USE THEREOF

      
Numéro d'application CN2023095666
Numéro de publication 2024/239219
Statut Délivré - en vigueur
Date de dépôt 2023-05-23
Date de publication 2024-11-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Yanyang
  • Shen, Chaoyang
  • Kong, Bo
  • Jia, Yulu
  • Pan, Bingcai
  • Zhang, Weiming

Abrégé

m2nn](3-m)+233344 crystals, thereby guaranteeing the stable phosphorus removal capacity thereof.

Classes IPC  ?

  • C01G 49/00 - Composés du fer
  • B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
  • B82Y 40/00 - Fabrication ou traitement des nanostructures
  • C02F 1/52 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par floculation ou précipitation d'impuretés en suspension

11.

LAMB WAVE RESONATOR HAVING THROUGH HOLE

      
Numéro d'application CN2024089498
Numéro de publication 2024/239893
Statut Délivré - en vigueur
Date de dépôt 2024-04-24
Date de publication 2024-11-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yu, Siyuan
  • Wu, Shumao
  • Qin, Zhenhui
  • Hao, Chenbei
  • Chen, Yanfeng

Abrégé

33 thin film thicknesses; in addition, the solution can greatly improve the flexibility in design, compactness, mechanical stability, temperature stability and power tolerance of devices.

Classes IPC  ?

  • H03H 9/02 - Réseaux comprenant des éléments électromécaniques ou électro-acoustiquesRésonateurs électromécaniques Détails

12.

CONJUGATE AND THE PREPARATION THEREOF

      
Numéro d'application CN2024091644
Numéro de publication 2024/235071
Statut Délivré - en vigueur
Date de dépôt 2024-05-08
Date de publication 2024-11-21
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Jiao, Jinbiao
  • Li, Jie
  • Wu, Qingsong
  • Hu, Yudi
  • Fan, Mingxin

Abrégé

a122 comprises a functional molecule.

Classes IPC  ?

  • A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
  • C07C 309/81 - Halogénures d'acides sulfoniques ayant des groupes halogénosulfonyle liés à des atomes de carbone acycliques d'un squelette carboné non saturé
  • A61P 35/00 - Agents anticancéreux

13.

In-situ testing system for semiconductor device in aerospace irradiation environment

      
Numéro d'application 18631171
Numéro de brevet 12146908
Statut Délivré - en vigueur
Date de dépôt 2024-04-10
Date de la première publication 2024-11-19
Date d'octroi 2024-11-19
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Feng
  • Wang, Wenfeng
  • Lu, Hai
  • Xu, Weizong
  • Zhou, Dong
  • Ren, Fangfang

Abrégé

The present invention discloses an in-situ testing system for semiconductor device in aerospace irradiation environment. The present invention includes a static testing unit, a static testing channel, a dynamic testing unit, a dynamic testing channel, and a channel switching control unit; the static testing unit is connected to the device under test through the static testing channel, and is used to output static testing signals and display the static testing data of the device under test; the dynamic testing unit is connected to the device under test through the dynamic testing channel, and is used to output dynamic testing signals and display the dynamic testing data of the device under test; the channel switching control unit is connected to the static testing channel and the dynamic testing channel, respectively. This invention can achieve static, dynamic, and degradation testing of third-generation semiconductor device in aerospace irradiation environment.

Classes IPC  ?

  • G01R 31/28 - Test de circuits électroniques, p. ex. à l'aide d'un traceur de signaux

14.

QUANTUM DIGITAL SIGNATURE METHOD AND QUANTUM DIGITAL SIGNCRYPTION METHOD

      
Numéro d'application 18247151
Statut En instance
Date de dépôt 2022-09-14
Date de la première publication 2024-10-31
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • MATRICTIME DIGITAL TECHNOLOGY CO., LTD (Chine)
Inventeur(s)
  • Yin, Hua-Lei
  • Weng, Chen-Xun
  • Fu, Yao
  • Chen, Zeng-Bing

Abrégé

Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.

Classes IPC  ?

  • H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
  • H04L 9/08 - Répartition de clés

15.

OCEAN CURRENT DETECTION DEVICE AND METHOD BASED ON DOUBLE-HELIX AND DOUBLE-CORE VIBRATION FIBER-OPTIC CABLE

      
Numéro d'application 18349384
Statut En instance
Date de dépôt 2023-07-10
Date de la première publication 2024-10-24
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Zhang, Yixin
  • Zhang, Chi
  • Zhang, Xuping
  • Tong, Shuai
  • Wang, Shun
  • Ding, Chenyang
  • Wang, Feng

Abrégé

An ocean current detection device and method based on double-helix and double-core vibration fiber-optic cable, comprises a double-core fiber-optic cable and a φ-OTDR system; the double-core fiber-optic cable comprises a first and a second optical fiber core, provided symmetrically in the double helix structure. The terminate ends of the first and the second optical fiber core are connected, and the start end of the first or the second optical fiber core is connected with the φ-OTDR system. When measuring the ocean current characteristics in the target sea area, the double-core fiber-optic cable is provided underwater to generate vortex-induced vibration. The φ-OTDR system is provided for emitting laser towards the cable, receiving returned double-core vibration signals, extracting vibration characteristics from the double-core vibration signals to determine ocean current characteristics, including ocean current flow velocity and direction, to improve the detection accuracy.

Classes IPC  ?

  • G01P 5/26 - Mesure de la vitesse des fluides, p. ex. d'un courant atmosphériqueMesure de la vitesse de corps, p. ex. navires, aéronefs, par rapport à des fluides en mesurant l'influence directe du courant de fluide sur les propriétés d'une onde optique de détection
  • G01P 13/02 - Indication de la direction uniquement, p. ex. par une girouette

16.

USE OF PROTEIN SEQUENCE CAPABLE OF BINDING TO SUBSTRATE IN PREPARATION OF PRODUCT FOR INHIBITING FIBRIN ASSEMBLY

      
Numéro d'application 18650037
Statut En instance
Date de dépôt 2024-04-29
Date de la première publication 2024-10-24
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE (Chine)
  • HUAZHONG AGRICULTURAL UNIVERSITY (Chine)
Inventeur(s)
  • Dong, Xianchi
  • Liu, Wen
  • Ding, Jianping
  • Shi, Yu
  • Xu, Shutong
  • Xu, Jianbo

Abrégé

Provided are a protein containing an amino acid sequence capable of binding to a peptide fragment of a substrate GPRP, a fibrinogen-like protein 1 (FGL1) containing the amino acid sequence, and a fibrinogen domain (FD) of the FGL1, wherein a single FD protein also has a function the same as or similar to that of the FGL1. The FGL1 and FD, which have different action mechanisms from existing drugs, can inhibit fibrin assembly in the process of thrombogenesis by means of competing for fibrin substrate binding pockets. The FGL1 and FD can have a stronger affinity to the substrate by means of mutation, thereby effectively enhancing a usage effect of drugs for treating thrombus.

Classes IPC  ?

  • C07K 14/75 - Fibrinogène
  • A61K 38/00 - Préparations médicinales contenant des peptides
  • A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
  • A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
  • A61P 7/02 - Agents antithrombotiquesAnticoagulantsAnti-agrégants plaquettaires
  • C07K 1/22 - Chromatographie d'affinité ou techniques analogues basées sur des procédés d'absorption sélective
  • C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales

17.

MONITORING SYSTEM AND METHOD FOR BROKEN WIRES IN PCCP BASED ON DISTRIBUTED OPTICAL FIBER SENSING

      
Numéro d'application 18357572
Statut En instance
Date de dépôt 2023-07-24
Date de la première publication 2024-10-24
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Zhang, Yixin
  • Tong, Shuai
  • Zhang, Xuping
  • Tang, Shaoxiong
  • Wang, Ruofan
  • Wang, Haoran
  • Wang, Shun
  • Wang, Feng

Abrégé

A monitoring system and method for broken wires in PCCP based on distributed optical fiber sensing relates to the technical field of optical fiber sensing. The monitoring system for broken wires in PCCP comprises a Sagnac interferometer, a Φ-OTDR system, a dual loopback system and a signal processing system. The Sagnac interferometer comprises a first laser, a first optical coupler, a first delay optical fiber, a Faraday rotating mirror and a first photodetector. The Φ-OTDR system comprises a second laser, a second optical coupler, an acousto-optic modulator, a circulator, a third optical coupler and a second photodetector. The dual loopback system comprises a wavelength division multiplexer and a second delay optical fiber. The invention solves the problems of low positioning accuracy, limited frequency measurement range, detection dead zone and high computing pressure in monitoring broken wires in PCCP.

Classes IPC  ?

  • G01N 21/95 - Recherche de la présence de criques, de défauts ou de souillures caractérisée par le matériau ou la forme de l'objet à analyser
  • G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique

18.

METHOD AND DEVICE FOR IMAGING AND CALCULATION, AND READABLE MEDIUM

      
Numéro d'application CN2023087788
Numéro de publication 2024/212125
Statut Délivré - en vigueur
Date de dépôt 2023-04-12
Date de publication 2024-10-17
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yan, Feng
  • Wang, Kai
  • Li, Wenbin
  • Huo, Jing

Abrégé

Disclosed in the present invention are a method and device for imaging and calculation, and a computer readable medium. The method comprises: extracting a field of view image of a target field of view, and searching the field of view for a specific target; according to the attribute of the specific target, determining a calculation kernel corresponding to the specific target, wherein the calculation kernel is expressed by a weight value matrix; performing convolution calculation in an imaging region by using the calculation kernel; and performing searching and matching on the field of view image to obtain a feature map corresponding to the specific target.

Classes IPC  ?

  • G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]

19.

METAL-RESIN COMPOSITE, SURFACE TREATMENT METHOD, AND SUBSTRATE OF CIRCUIT BOARD FOR HIGH-FREQUENCY AND HIGH-SPEED SIGNAL TRANSMISSION

      
Numéro d'application 18632326
Statut En instance
Date de dépôt 2024-04-11
Date de la première publication 2024-10-17
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • JIANGSU HHCK ADVANCED MATERIALS CO., LTD. (Chine)
Inventeur(s)
  • Chen, Wei
  • Xue, Qi
  • Zhuang, Huijie
  • Li, Linling
  • Han, Jianglong
  • Zhou, Dongshan
  • Wang, Xiaoliang

Abrégé

A metal-resin composite, a surface treatment method, and a substrate of a printed circuit board (PCB) for high-frequency and high-speed signal transmission comprise a surface-treated metal, and the surface-treated metal includes a nano-scale pore array that is used for filling of a resin and vertically extends from a surface to an interior of a metal, where nano-scale pillars are provided to extend from bottoms to openings of nano-scale pores of the nano-scale pore array. The pillar-in-pore structure makes a resin entering a nano-scale pore have an ultra-high anchoring effect on a resin body outside the nano-scale pore. Therefore, on the premise of not using an additive such as a T liquid or a coupling agent, the present disclosure greatly improves a tensile bonding strength at an interface between a resin body and a metal substrate, and also eliminates a decline in an interfacial bonding strength of a composite.

Classes IPC  ?

  • B29C 45/14 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet en incorporant des parties ou des couches préformées, p. ex. moulage par injection autour d'inserts ou sur des objets à recouvrir
  • B29C 35/16 - Refroidissement
  • B29C 45/73 - Chauffage ou refroidissement du moule
  • B29K 33/00 - Utilisation de polymères d'acides non saturés ou de leurs dérivés comme matière de moulage
  • B29K 81/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du soufre avec ou sans azote, oxygène ou carbone comme matière de moulage
  • B29L 31/34 - Appareils électriques, p. ex. bougies ou leurs parties constitutives
  • C25D 11/02 - Anodisation
  • H05K 1/02 - Circuits imprimés Détails
  • H05K 1/03 - Emploi de matériaux pour réaliser le substrat

20.

METHOD AND SYSTEM FOR PREDICTING CARBON EMISSION FROM AGRICULTURAL LAND

      
Numéro d'application 18492715
Statut En instance
Date de dépôt 2023-10-23
Date de la première publication 2024-10-17
Propriétaire
  • Nanjing Agricultural University (Chine)
  • Nanjing University (Chine)
Inventeur(s)
  • Jiang, Penghui
  • Hu, Yi
  • Li, Manchun
  • Fu, Haiyue

Abrégé

The present invention provides a method and a system for predicting carbon emission from agricultural land, relates to the technical field of carbon emission prediction, comprising: Using the CLUMondo model to predict the agricultural land area of the target area at a future time; Determining methane emissions from paddy fields at a future time based on the area of rice planted in the agricultural land area; Determining the direct and indirect nitrous oxide emissions at a future time based on the nitrogen input to the agricultural land area; Determining methane emissions from animal enteric fermentation, methane emissions from animal manure management, and nitrous oxide emissions from animal manure management based on the number of animals in the agricultural land area.

Classes IPC  ?

  • G06Q 10/04 - Prévision ou optimisation spécialement adaptées à des fins administratives ou de gestion, p. ex. programmation linéaire ou "problème d’optimisation des stocks"
  • G06Q 50/02 - AgriculturePêcheForesterieExploitation minière

21.

ARRAYED NANOPORE MICRO-CURRENT SIGNAL PARALLEL MEASUREMENT APPARATUS

      
Numéro d'application CN2023088060
Numéro de publication 2024/207548
Statut Délivré - en vigueur
Date de dépôt 2023-04-13
Date de publication 2024-10-10
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Ying, Yilun
  • Long, Yitao
  • Zhong, Chengbing
  • Zhang, Linlin

Abrégé

An arrayed nanopore micro-current signal parallel measurement apparatus (2), comprising a gating apparatus (A) of a nanopore multi-path measurement unit, a multi-path nanopore current signal amplifying and signal processing apparatus (C), a multi-path nanopore current signal acquisition apparatus (B), an FPGA control chip (12), and a single-chip microcomputer (14). The arrayed nanopore micro-current signal parallel measurement apparatus can achieve high-bandwidth amplification and measurement of an arrayed nanopore micro-current signal, and ensures a signal sampling bandwidth by means of the high sampling rates of a bandwidth compensation circuit and an analog-to-digital converter. The gating apparatus (A) of the nanopore multi-path measurement unit can acquire the nanopore micro-current signal of a specified channel in a directional or polling manner, thereby achieving grouping control and polling sampling of a multi-path nanopore detection system. The arrayed nanopore micro-current signal parallel measurement apparatus not only can be applied to acquisition and reading of micro-current signals in nanopore protein molecule sequencing, but also can be used for detection of other micro-current measurement systems such as ion channel drug screening and single-particle collision electrochemical detection.

Classes IPC  ?

  • G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
  • G05B 19/04 - Commande à programme autre que la commande numérique, c.-à-d. dans des automatismes à séquence ou dans des automates à logique
  • G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
  • C12Q 1/6869 - Méthodes de séquençage

22.

SCENARIO TEST METHOD AND APPARATUS FOR DRIVING CONTROL SYSTEM, MEDIUM, AND DEVICE

      
Numéro d'application CN2023121923
Numéro de publication 2024/207700
Statut Délivré - en vigueur
Date de dépôt 2023-09-27
Date de publication 2024-10-10
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Bu, Lei
  • Jin, Yifan
  • Lv, Yulong
  • Wang, Jiawan
  • Li, Xuandong

Abrégé

Disclosed are a scenario test method and apparatus of a driving control system, a medium, and a device. According to the method, a state transition diagram is input, and then the test coverage of each state transition in the state transition diagram is gradually implemented on the basis of the state transition diagram and by means of a cyclic iterative variation of a scenario sample. When the cyclic iterative variation is performed, a simulation output of the scenario sample is used as a reference, so that an iterative process can quickly converge the purpose of corresponding state transitions thereof completing coverage testing. The present invention can visually test the processing capability and level of the driving control system for a driving environment, and has high test efficiency.

Classes IPC  ?

23.

NANO PORIN-BASED HIGH-THROUGHPUT DETECTION DEVICE

      
Numéro d'application CN2023088046
Numéro de publication 2024/183128
Statut Délivré - en vigueur
Date de dépôt 2023-04-13
Date de publication 2024-09-12
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Ying, Yilun
  • Zhang, Linlin
  • Long, Yitao

Abrégé

A nano porin-based high-throughput detection device, comprising a biochip (1), bilayer membranes (3), a micro-well group (12), micro-wells (7), and a pool body structure (13). One or more micro-well groups (12) are arranged on the biochip (1); the micro-well group (12) comprises a plurality of micro-wells (7); the whole pool body structure (13) is of a cylindrical structure with an upper opening and a lower opening; the pool body structure (13) is integrally tiled on the upper surface of the biochip (1) and is tightly connected to the biochip (1); an inner cavity of the pool body structure (13) is separately communicated with the plurality of micro-wells (7); a polar medium (4) containing porins (18) is injected into the inner cavity of the pool body structure (13); a micro-well opening (8) of each micro-well (7) is provided with a bilayer membrane (3); the porins (18) are inserted onto the bilayer membranes (3). According to the nano porin-based high-throughput detection device, the membrane forming throughput can be improved, the types of membranes formed at the same timer are increased, the membrane forming efficiency is improved, and various porins (18) can be accommodated.

Classes IPC  ?

  • G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
  • G01N 27/327 - Électrodes biochimiques
  • G01N 27/26 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant des variables électrochimiquesRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en utilisant l'électrolyse ou l'électrophorèse

24.

LAND USE STRUCTURE PATTERN LAYER MINING METHOD BASED ON GRAPH CONVOLUTIONAL NETWORK

      
Numéro d'application CN2024094646
Numéro de publication 2024/179621
Statut Délivré - en vigueur
Date de dépôt 2024-05-22
Date de publication 2024-09-06
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Chen, Zhenjie
  • Ge, Lanfeng
  • Tu, Xinmeng
  • Zhou, Chen
  • Chen, Fei
  • Nie, Beidou
  • Du, Jiaxin

Abrégé

The present invention relates to a land use structure pattern layer mining method based on a graph convolutional network, which comprises the following steps: obtaining land use data; constructing a graph structure; generating a label input model; training the label input model by means of a graph convolutional network model, and generating a graph embedding; utilizing a spatially constrained multivariate clustering method to perform separation on the graph embedding, and obtaining a layered partition structure from partitions to each level of sub-partitions; separately using land use type frequency characteristics for each year of land use data to construct region-level primitives for each region; and representing temporo-spatial changes to the land use structure of a region according to the changes to region-level primitives of said region in different years. The influence of multiple orders of neighboring areas are taken into account when the primitives are constructed, partitioning can be carried out according to differences in land use spatial structures, and layered land use structure patterns and dynamic characteristics thereof can be effectively mined.

Classes IPC  ?

  • G06N 5/025 - Extraction de règles à partir de données

25.

WAVE-ABSORBING STRUCTURE AND DEVICE

      
Numéro d'application CN2023078443
Numéro de publication 2024/178541
Statut Délivré - en vigueur
Date de dépôt 2023-02-27
Date de publication 2024-09-06
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • NANJING STAR HIDDEN TECHNOLOGY DEVELOPMENT CO., LTD. (Chine)
Inventeur(s)
  • Lai, Yun
  • Wang, Cong
  • Chu, Hongchen
  • Mou, Wenri

Abrégé

The present invention relates to a wave-absorbing structure and a device. The wave-absorbing structure comprises a metasurface structure and at least one wave-absorbing material provided on the metasurface structure; the metasurface structure is provided with a plurality of metasurface units, each metasurface unit has a corresponding regulation and control parameter, and the regulation and control parameter of each metasurface unit is configured to: convert, on the metasurface structure, an incident electromagnetic wave into at least one pair of surface waves which can be absorbed by the at least one wave-absorbing material; and the at least one pair of surface waves propagate in opposite directions along the metasurface structure and overlap at the position of the at least one wave-absorbing material. According to the wave-absorbing structure, a metasurface structure is use to replace a resonant cavity, an optical splitter and a phase shifter in a conventional laboratory structure, reducing the complexity of an electromagnetic wave-absorbing system, and successfully bringing a coherent wave-absorbing scenario into a general electromagnetic environment.

Classes IPC  ?

  • H01Q 17/00 - Dispositifs pour absorber les ondes rayonnées par une antenneCombinaisons de tels dispositifs avec des éléments ou systèmes d'antennes actives

26.

TEMPERATURE MEASUREMENT METHOD AND APPARATUS BASED ON PASSIVE RFID TAG

      
Numéro d'application 18570703
Statut En instance
Date de dépôt 2021-06-18
Date de la première publication 2024-09-05
Propriétaire
  • JIANGSU TOOKER ROBOTICS CO., LTD. (Chine)
  • NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Liu, Jia
  • Chen, Lijun
  • Chen, Xingyu
  • Zhang, Xu
  • Wang, Fuxing

Abrégé

A temperature measurement method based on a passive RFID tag. The method comprises: acquiring a circuit temperature feature of a tag multiple times, and establishing a tag temperature-feature correspondence; and estimating, by using the tag temperature-feature correspondence and the current circuit temperature feature of the tag, the temperature of an environment where the tag is located, wherein the circuit temperature feature of the tag is the persistence time within which a passive RFID tag can operate normally during a discharging process after the tag is fully charged. By means of the method, a robust and accurate temperature measurement is achieved, and a tag can be directly deployed on an existing commercial RFID device without modifying the hardware of the tag and a reader.

Classes IPC  ?

  • G01K 11/00 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou
  • G06K 19/07 - Supports d'enregistrement avec des marques conductrices, des circuits imprimés ou des éléments de circuit à semi-conducteurs, p. ex. cartes d'identité ou cartes de crédit avec des puces à circuit intégré

27.

METHOD FOR CONFIRMING OWNERSHIP OF DIGITAL ASSETS BASED ON HASH ALGORITHM AND METHOD FOR TRACING TO A SOURCE OF DIGITAL ASSETS BASED ON HASH ALGORITHM

      
Numéro d'application 18245383
Statut En instance
Date de dépôt 2022-09-14
Date de la première publication 2024-09-05
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • MATRICTIME DIGITAL TECHNOLOGY CO., LTD (Chine)
Inventeur(s)
  • Chen, Zengbing
  • Xu, Tongkai
  • Zhu, Mengya
  • Foo, Boohea
  • Yang, Ge
  • Zhao, Chengyang

Abrégé

Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.

Classes IPC  ?

  • H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
  • H04L 9/06 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité l'appareil de chiffrement utilisant des registres à décalage ou des mémoires pour le codage par blocs, p. ex. système DES

28.

IMAGING SYSTEM, PREPARATION METHOD, AND IMAGE CAPTURING APPARATUS

      
Numéro d'application CN2024077834
Numéro de publication 2024/175010
Statut Délivré - en vigueur
Date de dépôt 2024-02-20
Date de publication 2024-08-29
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s) Hong, Xuhao

Abrégé

The present invention relates to an imaging system, a preparation method, and an image capturing apparatus. The imaging system successively comprises, from an object side to an image side along an optical axis: a light source, configured to provide light irradiated to a sample; an imaging lens group, configured to receive light transmitted by the sample to image the sample at least once; and a phase modulation unit, configured to modulate light transmitted by the imaging lens group to form an expected sample image on an imaging surface of the imaging system. A plane where the phase modulation unit is located and a plane where the light source is located are a pair of conjugate planes; no lens or lens group for Fourier transform is introduced into at least an optical path between the plane where the phase modulation unit is located and the imaging surface of the imaging system. According to the imaging system, more diverse imaging effects can be achieved without changing an original microscopic imaging optical path basically, the resolution reduction can be avoided, and the imaging quality can be improved.

Classes IPC  ?

  • G02B 21/02 - Objectifs
  • G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
  • G01N 21/03 - Détails de structure des cuvettes
  • G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique
  • G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
  • G02B 21/08 - Condensateurs
  • G02B 21/14 - Condensateurs donnant un éclairage pour une observation en contraste de phase
  • G02B 7/00 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques
  • G02B 5/30 - Éléments polarisants

29.

STRUCTURAL-PROFILING OF ANALYTES BY NANOPORE TRAPPING

      
Numéro d'application 18560547
Statut En instance
Date de dépôt 2022-05-12
Date de la première publication 2024-08-15
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Huang, Shuo
  • Liu, Yao
  • Wang, Yuqin
  • Zhang, Shanyu

Abrégé

A method of characterizing an analyte or the interaction between the analyte and an agent in a nanopore system, wherein the nanopore system comprises a protein nanopore disposed in a membrane that separates a first conductive liquid medium from a second conductive liquid medium, wherein the protein nanopore is MspA, MspA homolog or variant thereof, wherein the analyte has an conformation and the analyte with the conformation can be accommodated in the vestibule of the MspA, the MspA homolog or the variant thereof but cannot translocate through the MspA, the MspA homolog or the variant thereof, the method comprising: i) applying an electrical potential difference between the first conductive liquid medium and the second conductive liquid medium to drive the analyte into the nanopore, and optionally contacting the agent with the analyte; ii) measuring an ionic current through the protein nanopore to provide a tested current pattern that contains at least ionic current measured during the analyte is in the vestibule of the MspA, the MspA homolog or the variant thereof; iii) associating the tested current pattern with at least one characteristic of the analyte or the interaction between the analyte and an agent.

Classes IPC  ?

  • G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
  • G01N 33/04 - Produits laitiers

30.

AC Current Sensor And Wireless Charging Chip

      
Numéro d'application 18465954
Statut En instance
Date de dépôt 2023-09-12
Date de la première publication 2024-08-15
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Qiu, Hao
  • Zhang, Xusheng
  • Shi, Yi

Abrégé

Disclosed in the present application are an AC current sensor and a wireless charging chip. The AC current sensor includes an integrator circuit, a differentiator circuit, and a calibration circuit. The integrator circuit is configured to perform integration on a voltage on which filter processing is performed across an inductor in a TX coil. The differentiator circuit is configured to perform differentiation on a voltage on which filter processing is performed across a capacitor in the TX coil. The calibration circuit is configured to sample and compare output signals of the integrator circuit and the differentiator circuit, and adjust output results of the integrator circuit and the differentiator circuit until the output results are the same. In this case, the output result of the differentiator circuit may be used to calculation for a current flowing through the TX coil.

Classes IPC  ?

  • G01R 19/10 - Mesure d'une somme, d'une différence, ou d'un rapport
  • H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance

31.

CONJUGATE AND THE PREPARING METHOD AND USE THEREOF

      
Numéro d'application 18554325
Statut En instance
Date de dépôt 2022-04-08
Date de la première publication 2024-08-08
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Li, Jie
  • Wu, Qingsong
  • Sha, Wanxing
  • Yang, Yang

Abrégé

A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1 A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1 A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1 wherein R is —F or —OH, and L2 is linked to R1, R3 or R2, a is an integer of 1 to 10, b, c is each independently an integer of 0 to 10, provided that b and c are not simultaneously 0. R1, R2, and R3, may independently be H, optionally substituted alkyl, or optionally substituted aryl, and R1, may be H or isotope thereof Δ C may link R1 and a C linking R2 form a ring.

Classes IPC  ?

  • A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
  • A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
  • A61P 35/00 - Agents anticancéreux

32.

TRANSMISSION STRUCTURE AND PREPARATION METHOD THEREOF

      
Numéro d'application 18634296
Statut En instance
Date de dépôt 2024-04-12
Date de la première publication 2024-08-08
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • NANJING STAR HIDDEN TECHNOLOGY DEVELOPMENT CO., LTD. (Chine)
Inventeur(s)
  • Chu, Hongchen
  • Lai, Yun
  • Xiong, Xiang
  • Peng, Ruwen
  • Wang, Mu

Abrégé

The present disclosure relates to a transmission structure and a preparation method thereof. The transmission structure includes a plurality of first transmission units and a plurality of second transmission units, and difference between a first transmission phase of a transmitted electromagnetic wave of the first transmission unit and a second transmission phase of a transmitted electromagnetic wave of the second transmission unit is the same or similar within a preset frequency range. The plurality of first and second transmission units are arranged randomly on a surface. The first transmission unit has a first matrix, a first medium block is disposed inside the first matrix, and a thickness of the first matrix between the first medium block and an electromagnetic wave incident surface of the first transmission unit is a non-zero first thickness. The second transmission unit has a second matrix, a second medium block is disposed inside the second matrix, a thickness of the second matrix between the second medium block and an electromagnetic wave incident surface of the second transmission unit is a non-zero second thickness, and the first and second thicknesses are configured to enable the first and second transmission units to have a large phase difference of reflected electromagnetic waves in a wide frequency range.

Classes IPC  ?

33.

BIOLOGICAL WASTEWATER TREATMENT PROCESS RECONSTRUCTION METHOD AND SYSTEM BASED ON MACHINE LEARNING

      
Numéro d'application CN2023118126
Numéro de publication 2024/159750
Statut Délivré - en vigueur
Date de dépôt 2023-09-12
Date de publication 2024-08-08
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wang, Jinfeng
  • Hu, Jie
  • Ren, Hongqiang

Abrégé

Disclosed in the present invention are a biological wastewater treatment process reconstruction method and system based on machine learning. The method comprises: collecting influent and effluent water basic quality, ecological risk and process information data in a biological wastewater treatment procedure, and performing data preprocessing; performing feature extraction on biological wastewater treatment processes and performing multi-unit representation; constructing effluent water basic quality prediction models and effluent water ecological risk prediction models of different biological treatment multi-unit combined processes, and inspecting whether same are up to standard; simulating and reconstructing different biological wastewater treatment short-range unit combined processes, and inspecting whether the effluent water quality is up to standard in scenarios with different influent water qualities; and assessing the ecological risk of reconstructed biological treatment short-range unit combined processes, the effluent water quality of which is up to standard, and determining an optimal biological wastewater treatment process. By means of the present invention, a new biological treatment process that meets the requirements of the effluent water basic quality being up to standard and the biological risk being the lowest can be determined for scenarios with different influent water qualities, thereby removing the selection limitation of existing biological treatment process methods.

Classes IPC  ?

  • C02F 3/00 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout
  • C02F 3/30 - Procédés aérobies et anaérobies
  • G06N 20/00 - Apprentissage automatique

34.

IMAGING METHOD AND APPARATUS, AND COMPUTER-READABLE MEDIUM

      
Numéro d'application 18560355
Statut En instance
Date de dépôt 2022-05-13
Date de la première publication 2024-07-11
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Hu, Xuemei
  • Qiu, Chenxi
  • Wang, Kai
  • Yue, Tao
  • Yan, Feng
  • Pan, Hongbing

Abrégé

Provided are an imaging method and apparatus, and a medium. The method includes: for a target field of view, performing photographing and quantification at a first resolution, to obtain a first image that has a first bit width; for the target field of view, performing photographing and differential processing at a second resolution, to obtain a second image that has a second bit width, wherein the differential processing includes: for a pixel point obtained by photographing at the second resolution, quantifying the difference between the pixel point and a neighboring pixel point of the pixel point, to obtain a quantified difference a value of a corresponding pixel point in the second image; and fusing the first image with the second image, to obtain a third image, wherein the first resolution is lower than the second resolution, and the first bit width is higher than the second bit width.

Classes IPC  ?

  • G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
  • G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
  • H04N 19/93 - Codage par longueur de plage
  • H04N 23/698 - Commande des caméras ou des modules de caméras pour obtenir un champ de vision élargi, p. ex. pour la capture d'images panoramiques

35.

DETECTION DEVICES FOR LASER SPOT WELDING MICRO-WELD SPOT QUALITY BASED ON LASER

      
Numéro d'application 18586381
Statut En instance
Date de dépôt 2024-02-23
Date de la première publication 2024-07-11
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Lu, Minghui
  • Ding, Lei
  • Yan, Xuejun
  • Lu, Qiangbing
  • Xu, Xiaodong
  • Chen, Yanfeng

Abrégé

Embodiments of the present disclosure provide a detection device for laser spot welding micro-weld spot quality based on laser ultrasound. The device includes: a nanosecond pulsed laser configured to emit a laser; the polarizing beam splitter configured to perform a laser beam splitting, wherein a laser beam after performing the laser beam splitting by the polarizing beam splitter enter an energy detector and a beam splitter mirror, respectively; the beam splitter mirror configured to perform the laser beam splitting on the laser entering the beam splitter mirror, wherein a laser beam after performing the laser beam splitting enter a photodetector and a light reflecting mirror, respectively; an aperture configured for the laser beam passing through the light reflecting mirror, the laser passing through a scanning galvanometer to reach a multi-axis displacement platform; the multi-axis displacement platform configured to place and/or move a sample.

Classes IPC  ?

  • B23K 26/03 - Observation, p. ex. surveillance de la pièce à travailler
  • B23K 26/06 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples
  • B23K 26/0622 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser par impulsions de mise en forme
  • B23K 26/067 - Division du faisceau en faisceaux multiples, p. ex. foyers multiples
  • B23K 26/22 - Soudage par points
  • B23K 31/12 - Procédés relevant de la présente sous-classe, spécialement adaptés à des objets ou des buts particuliers, mais non couverts par un seul des groupes principaux relatifs à la recherche des propriétés, p. ex. de soudabilité, des matériaux

36.

Retinomorphic sensor array and image convolution method therefor

      
Numéro d'application 17769609
Numéro de brevet 12132134
Statut Délivré - en vigueur
Date de dépôt 2020-03-26
Date de la première publication 2024-07-11
Date d'octroi 2024-10-29
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Miao, Feng
  • Liang, Shijun
  • Wang, Chenyu

Abrégé

A retinomorphic sensor array and a convolution method are used for image processing therefor, wherein the optoelectronic sensor has a vertically stacked heterostructure provided with a bottom electrode, a dielectric layer, a channel layer, a source electrode and a drain electrode on a base, the source and drain electrode are mutually opposite and are arranged at two ends of the channel layer, the bottom electrode, the source and drain electrode are made of a material used by a flexible electrode, an inert metal or a semimetal, the dielectric layer is made of an insulating material, the channel layer is made of a bipolar material, and the base comprises a substrate and an insulating material layer generated on a surface of the substrate.

Classes IPC  ?

  • H01L 31/113 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par un fonctionnement par effet de champ, p.ex. phototransistor à effet de champ à jonction du type conducteur-isolant-semi-conducteur, p.ex. transistor à effet de champ métal-isolant-semi-conducteur
  • H01L 31/0224 - Electrodes
  • H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
  • H04N 25/47 - Capteurs d'images avec sortie d'adresse de pixelCapteurs d'images commandés par événementSélection des pixels à lire en fonction des données d'image
  • H01L 31/032 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés non couverts par les groupes

37.

NUCLEIC ACID DELIVERY SYSTEM AND APPLICATION THEREOF

      
Numéro d'application 18373605
Statut En instance
Date de dépôt 2023-09-27
Date de la première publication 2024-07-11
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Chenyu
  • Chen, Xi
  • Fu, Zheng
  • Li, Jing
  • Zhang, Xiang
  • Zhou, Xinyan
  • Zhang, Li
  • Yu, Mengchao
  • Guo, Hongyuan

Abrégé

An isolated nucleic acid, a plasmid or viral vector thereof and a pharmaceutical composition thereof, and a method for treating a disease. The nucleic acid and the vector comprise at least one RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function, can be delivered into a host body, are enriched in an organ tissue of a host, and are self-assembled to form and secrete an exosome and target a target tissue, thereby treating the disease.

Classes IPC  ?

  • C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
  • A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
  • C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
  • C12N 15/86 - Vecteurs viraux

38.

METHOD FOR CORRECTING DOT PRODUCT ERROR OF VARIABLE RESISTOR ARRAY

      
Numéro d'application 18558185
Statut En instance
Date de dépôt 2022-09-23
Date de la première publication 2024-07-04
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Miao, Feng
  • Liang, Shijun
  • Wang, Cong
  • Zhao, Yichen

Abrégé

Disclosed is a method for correcting a dot product error of a variable resistor array. The method includes: (1) initializing and writing a target conductance matrix into the variable resistor array; (2) calculating an effective conductance matrix of the variable resistor array; and (3) comparing the effective conductance matrix obtained in step (2) with the target conductance matrix, finishing executing the method in a case that a convergence condition is satisfied, and otherwise, continuing to execute steps as follows: multiplying a difference matrix by an adjustment coefficient η, such that an error conductance matrix is obtained; adjusting a conductance matrix Gwrite of actual variable resistors to Gwrite=G′write− Gerror, where Gerror is the error conductance matrix, G′write is a conductance matrix actually written into variable resistors last time; and executing steps (2) and (3) repeatedly after adjustment until a stop condition in step (3) is satisfied.

Classes IPC  ?

  • G06F 7/544 - Méthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs n'établissant pas de contact, p. ex. tube, dispositif à l'état solideMéthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs non spécifiés pour l'évaluation de fonctions par calcul
  • G06F 17/16 - Calcul de matrice ou de vecteur

39.

Solid-phase extraction material, and preparation method and use thereof

      
Numéro d'application 17910312
Numéro de brevet 12220685
Statut Délivré - en vigueur
Date de dépôt 2022-05-06
Date de la première publication 2024-06-27
Date d'octroi 2025-02-11
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Qing
  • Zhang, Ziang
  • Chen, Junxia
  • Chen, Yurong
  • Lei, Chongtian
  • Wang, Ranqiu
  • Zhou, Weiwei
  • Zhang, Libin

Abrégé

The present invention relates to the field of solid-phase extraction, and particularly to a solid-phase extraction material, and a preparation method and use thereof. The preparation method includes prepolymerizing the monomers N-vinylpyrrolidone and divinylbenzene in the presence of a chain transfer agent, adding prepolymer dropwise to an emulsion of monodispersed seed microspheres, swelling, and reacting to prepare white spheres; and functionalizing the white spheres, to obtain the solid-phase extraction material. The solid-phase extraction material prepared by the reaction has good spherical morphology, large specific surface area, and high ion exchange capacity. The prepared solid-phase extraction material functions in the separation and enrichment of PPCPs by means of a variety of forces with a high extraction rate. The extraction rate is basically maintained between 85% and 105%, and acidic, alkaline, neutral and amphoteric substances is capable of being selectively separated.

Classes IPC  ?

  • B01J 20/26 - Composés macromoléculaires synthétiques
  • B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
  • C02F 1/26 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par extraction

40.

A BIOORTHOGONAL CYCLOADDITION REACTION AND USE THEREOF

      
Numéro d'application CN2023139889
Numéro de publication 2024/131790
Statut Délivré - en vigueur
Date de dépôt 2023-12-19
Date de publication 2024-06-27
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Yan
  • Wang, Huan
  • Li, Jinbo

Abrégé

A bioorthogonal cycloaddition reaction is provided, as well as the use in assembly of TAC-type molecules and use in preparation of bioconjugates. A method of performing a coupling reaction, comprising providing a first structure comprising a dione group or derivative thereof and a second structure capable of providing anionic furan-2-olate or derivative thereof.

Classes IPC  ?

  • A61L 27/52 - Hydrogels ou hydrocolloïdes
  • C07K 1/00 - Procédés généraux de préparation de peptides

41.

A BIOORTHOGONAL CYCLOADDITION REACTION AND USE THEREOF

      
Numéro d'application CN2022140215
Numéro de publication 2024/130526
Statut Délivré - en vigueur
Date de dépôt 2022-12-20
Date de publication 2024-06-27
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Yan
  • Wang, Huan

Abrégé

Provided is a bioorthogonal cycloaddition reaction, as well as the use in assembly of TAC-type molecules and use in preparation of bioconjugates.

Classes IPC  ?

  • C07K 1/00 - Procédés généraux de préparation de peptides
  • C07D 491/20 - Systèmes condensés en spiro
  • C07D 307/77 - Composés hétérocycliques contenant des cycles à cinq chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle condensés en ortho ou en péri avec des carbocycles ou avec des systèmes carbocycliques

42.

Silicon carbide-based lateral PN junction extreme ultraviolet detector based on selective-area ion implantation, and preparation method thereof

      
Numéro d'application 18588391
Numéro de brevet 12080821
Statut Délivré - en vigueur
Date de dépôt 2024-02-27
Date de la première publication 2024-06-20
Date d'octroi 2024-09-03
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Lu, Hai
  • Zhou, Dong
  • Xu, Weizong

Abrégé

The present invention discloses a novel silicon carbide-based lateral PN junction extreme ultraviolet detector with enhanced detection performance based on selective-area ion implantation, including an N-type ohmic contact lower electrode, an N-type substrate and a lightly-doped epitaxial layer which are connected sequentially from bottom to top, where the lightly-doped epitaxial layer is an N-type lightly-doped epitaxial layer or a P-type lightly-doped epitaxial layer; in a case that the lightly-doped epitaxial layer is an N-type or P-type lightly-doped epitaxial layer, a P-type or N-type well region is formed on the surface of the N-type or P-type lightly-doped epitaxial layer through the selective-area ion implantation, a P-type or N-type ohmic contact upper electrode is arranged on the P-type or N-type well region, and the P-type or N-type ohmic contact upper electrode is provided with a metal conductive electrode along its periphery.

Classes IPC  ?

  • H01L 31/103 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par une seule barrière de potentiel ou de surface la barrière de potentiel étant du type PN à homojonction
  • H01L 31/0224 - Electrodes
  • H01L 31/0312 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIVBIV, p.ex. SiC
  • H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives

43.

CHEMICAL SAMPLE INDEXING FOR HIGH-THROUGHPUT SINGLE-CELL ANALYSIS

      
Numéro d'application 18549884
Statut En instance
Date de dépôt 2022-03-10
Date de la première publication 2024-06-13
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • SINGLERON (NANJING) BIOTECHNOLOGIES, LTD. (Chine)
Inventeur(s)
  • Li, Jie
  • Zhao, Xinlu
  • Yu, Wenhao
  • Yang, Yang
  • Zhu, Wenqi
  • Sun, Dafei
  • Ding, Xiuheng

Abrégé

The present disclosure provides methods, compositions, and kits for high-throughput single-cell analysis, such as nucleic acid analysis. In some embodiments, methods, compositions and kits for indexing a plurality of samples are provided. In some embodiments, methods, compositions and kits for high-throughput single-cell nucleic acid analysis, such as RNA sequencing are provided. The present disclosure allows fast, efficient and convenient cell labeling and sample pooling without being limited by cell types.

Classes IPC  ?

  • C12Q 1/6881 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour le typage de tissu ou de cellule, p. ex. sondes d’antigène leucocytaire humain [HLA]
  • C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
  • C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]

44.

METHOD FOR RECYCLING SILVER FROM WASTE IC CHIPS USING SOLUBLE STARCH

      
Numéro d'application 18210646
Statut En instance
Date de dépôt 2023-06-15
Date de la première publication 2024-06-13
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Qu, Zhan
  • Wang, Xianze
  • Ren, Hongqiang
  • Wang, Jinfeng
  • Liu, Junzhen
  • Chen, Yusen

Abrégé

A method for recycling silver from a waste IC chip include: heating to disassemble an IC chip, and crushing the IC chip into powders; adding the powders to a nitric acid solution, heating, centrifuging and collecting a first filtrate; adding soluble starch to the first filtrate, where a mass concentration ratio of the soluble starch to Fe in the first filtrate is 5.20-7.30; heating a resulting mixture to 130-175° C. for a first hydrothermal reaction, separating a precipitate from the first hydrothermal reaction and collecting a second filtrate; heating the second filtrate to 160-230° C. for a second hydrothermal reaction, separating a solid from the second hydrothermal reaction and collecting a third filtrate; drying, grinding, and sieving the solid to obtain silver powders; and adding alkali to the third filtrate to form a precipitate of Cu, and separating the precipitate to yield copper hydroxide.

Classes IPC  ?

  • C22B 11/00 - Obtention des métaux nobles
  • B22F 9/04 - Fabrication des poudres métalliques ou de leurs suspensionsAppareils ou dispositifs spécialement adaptés à cet effet par des procédés physiques à partir d'un matériau solide, p. ex. par broyage, meulage ou écrasement à la meule
  • B22F 9/24 - Fabrication des poudres métalliques ou de leurs suspensionsAppareils ou dispositifs spécialement adaptés à cet effet par un procédé chimique avec réduction de mélanges métalliques à partir de mélanges métalliques liquides, p. ex. de solutions
  • C01G 3/02 - OxydesHydroxydes
  • C22B 1/00 - Traitement préliminaire de minerais ou de débris ou déchets métalliques
  • C22B 3/22 - Traitement ou purification de solutions, p. ex. de solutions obtenues par lixiviation par des procédés physiques, p. ex. par filtration, par des moyens magnétiques
  • C22B 3/44 - Traitement ou purification de solutions, p. ex. de solutions obtenues par lixiviation par des procédés chimiques
  • C22B 7/00 - Mise en œuvre de matériaux autres que des minerais, p. ex. des rognures, pour produire des métaux non ferreux ou leurs composés

45.

DISPLAY MODULE, BACKLIGHT MODULE AND DISPLAY APPARATUS

      
Numéro d'application CN2023081597
Numéro de publication 2024/108823
Statut Délivré - en vigueur
Date de dépôt 2023-03-15
Date de publication 2024-05-30
Propriétaire
  • SVG TECH GROUP CO., LTD. (Chine)
  • SOOCHOW UNIVERSITY (Chine)
  • NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhao, Gaina
  • Zhu, Junqi
  • Yang, Ming
  • Qiao, Wen
  • Luo, Minghui
  • Li, Ruibin
  • Zhou, Xule
  • Jiang, Lin
  • Lu, Yanqing
  • Xu, Ting
  • Zhang, Weihua
  • Hu, Wei

Abrégé

A display module, a backlight module and a display apparatus. The display module comprises a main waveguide (102), an external light source (101) enters a waveguide layer by means of the main waveguide (102), and multiple paths of secondary waveguides (111-119) are fanned out by means of a light beam coupling unit (103), each path of secondary waveguide (111-119) corresponding to one row of pixels; and a high-collimation light beam is output after light output from pixel waveguides (121-130) pass through a collimating lens (150) and a light beam conversion structure (160). The backlight module comprises a pixel display module and two layers of electrowetting prism arrays (4, 5), and the collimated decoherence light passes through the two layers of electrowetting prism arrays (4, 5) to achieve angular deflection in the XY direction. The display apparatus comprises a backlight module, and upper and lower polarizers (6, 10), upper and lower TFT glass substrates (7, 9), a liquid crystal layer (8), a color filter layer (11), and a display phase plate (12) which are arranged at the light exiting end of the backlight module. The light passes through the display phase plate (12) to form left and right eye fields of view, thus generating a real 3D effect. By means of voltage control, the present invention not only improves the resolution and observation field of view of 3D display, but also achieves free switching between a 2D observation mode and a 3D observation mode.

Classes IPC  ?

  • G02B 30/33 - Systèmes ou appareils optiques pour produire des effets tridimensionnels [3D], p. ex. des effets stéréoscopiques en fournissant des première et seconde images de parallaxe à chacun des yeux gauche et droit d’un observateur du type autostéréoscopique comprenant des sources de lumière directionnelle ou des sources de rétroéclairage
  • G02F 1/13357 - Dispositifs d'éclairage

46.

LIGHT GUIDE PLATE, BACKLIGHT MODULE AND DISPLAY DEVICE

      
Numéro d'application CN2023109565
Numéro de publication 2024/109140
Statut Délivré - en vigueur
Date de dépôt 2023-07-27
Date de publication 2024-05-30
Propriétaire
  • NICROTEK CO., LTD (Chine)
  • SOOCHOW UNIVERSITY (Chine)
  • NANJINGUNIVERSITY (Chine)
Inventeur(s)
  • Fang, Zongbao
  • Fang, Hui
  • Zhang, Heng

Abrégé

A light guide plate (100), a backlight module, and a display device. The light guide plate (100) comprises: a light incident surface (110); a light emergent surface (120) connected to the light incident surface (110); and a bottom surface (130) arranged opposite the light emergent surface (120). The bottom surface (130) comprises a first region (S region) and a second region (P region) which are sequentially arranged in a direction away from the light incident surface (110). The distance from any point in the first region (S region) to the light incident surface (110) is less than the distance from any point in the second region (P region) to the light incident surface (110). A plurality of first light guide points (140) and a plurality of second light guide points (150) are provided in the first region (S region). A plurality of first light guide points (140) are provided in the second region (P region). The first light guide points (140) have first reflective surfaces (141) facing the light incident surface (110). Included angles between the first reflective surfaces (141) and the bottom surface (130) are first included angles (α1). The second light guide points (150) have second reflective surfaces (151) facing the light incident surface (110). Included angles between the second reflective surfaces (151) and the bottom surface (130) are second included angles (α2). The first included angles (α1) and the second included angles (α2) are less than or equal to 5°. Furthermore, the first included angles (α1) are smaller than the second included angles (α2). The light guide plate (100) can achieve narrow viewing angle display without affecting light-emitting uniformity.

Classes IPC  ?

47.

SILICA-COATED NANO PHASE CHANGE MATERIAL AND PREPARATION METHOD THEREFOR

      
Numéro d'application CN2023132963
Numéro de publication 2024/109744
Statut Délivré - en vigueur
Date de dépôt 2023-11-21
Date de publication 2024-05-30
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • HAIAN INSTITUTE OF HIGH-TECH RESEARCH, NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Tang, Shaochun
  • Jia, Suyue
  • Yang, Peng
  • Lu, Hongbin
  • Wu, Yang
  • Huang, Ye

Abrégé

22 nano-scale phase change material is prepared by means of a sol-gel method in combination with a microemulsion method under alkaline conditions. The material prepared in the present application has a particle size of about 500 nm, a phase change temperature of 27.7ºC, a phase change latent heat of 159.74 J/g, and a thermal decomposition temperature that is 50ºC higher than the thermal decomposition temperature of n-octadecane.

Classes IPC  ?

  • C09K 5/06 - Substances qui subissent un changement d'état physique lors de leur utilisation le changement d'état se faisant par passage de l'état liquide à l'état solide, ou vice versa

48.

MEMORY UNIT, STORAGE METHOD, MEMORY ARRAY, MEMORY AND MANUFACTURING METHOD THEREFOR

      
Numéro d'application CN2023131551
Numéro de publication 2024/104347
Statut Délivré - en vigueur
Date de dépôt 2023-11-14
Date de publication 2024-05-23
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yan, Feng
  • Shen, Fanxiang
  • Bu, Xiaofeng
  • Ma, Haowen

Abrégé

Provided in the present disclosure are a memory unit, a storage method, a memory array, a memory and a manufacturing method therefor. The storage method uses at least one three-dimensional dynamic random access memory unit and comprises: applying a suitable voltage to a selected gate layer used for storing information, so that a charge coupling layer controlled by the gate layer carries out dynamic random storage of information, first and second doped type material layers writing and resetting involved information in collaboration with each other; applying a suitable voltage to a selected gate layer for reading, so as to alter the on-off capability of a signal reading layer controlled by the gate layer, thereby reading out a voltage or current related to the information as third and fourth doped type material layers respectively serve as a source and a drain of the signal reading layer; and performing information storage in such a way of stacking layer by layer in the vertical direction or partition by partition in the horizontal direction the information stored in a plurality of gate layers. The method provided by the present disclosure can separate writing paths from reading paths, and has the characteristics such as high storage density, high speed and low power consumption.

Classes IPC  ?

  • G11C 5/02 - Disposition d'éléments d'emmagasinage, p. ex. sous la forme d'une matrice

49.

Activity recognition method of LRF large-kernel attention convolution network based on large receptive field

      
Numéro d'application 18392484
Numéro de brevet 11989935
Statut Délivré - en vigueur
Date de dépôt 2023-12-21
Date de la première publication 2024-05-21
Date d'octroi 2024-05-21
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • NANJING MORENEW DATA CO. LTD. (Chine)
Inventeur(s)
  • Hu, Guangwei
  • Teng, Qi
  • Pei, Lei
  • Pan, Wenwen
  • Huang, Qi
  • Zhang, Qianyou
  • Luo, Cheng
  • Liu, Yun

Abrégé

The disclosure relates to an activity recognition method of a large receptive field (LRF) large-kernel attention convolution network based on a large receptive field, the method includes the following steps: collecting an action signal, carrying out a preprocessing and a data partition on the action signal to obtain a data set; and training an LRF large-kernel attention convolution network model based on the data set, and introducing a trained LRF large-kernel attention convolution network model into a mobile wearable recognition device for human posture recognition.

Classes IPC  ?

  • G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
  • G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo

50.

SILICA-ENCAPSULATED NANO-PHASE CHANGE MATERIAL AND PREPARATION METHOD THEREOF

      
Numéro d'application 18416907
Statut En instance
Date de dépôt 2024-01-19
Date de la première publication 2024-05-16
Propriétaire
  • Nanjing University (Chine)
  • HAIAN INSTITUTE OF HIGH-TECH RESEARCH, NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Tang, Shaochun
  • Jia, Suyue
  • Yang, Peng
  • Lu, Hongbin
  • Wu, Yang
  • Huang, Ye

Abrégé

A silica-encapsulated nano-phase change material and its preparation method are provided. An n-octadecane SiO2 nanoscale phase change material is prepared by sol-gel and microemulsion coupling under alkaline conditions using silica as the shell material and n-octadecane as the core material in a microcapsule and using ethyl n-silicate as the silica source, cetyltrimethylammonium bromide as the emulsifier, and water and ethanol as the solvents. The materials prepared have a particle size of about 500 nm, a phase transition temperature of 27.7° C., a latent heat of phase transition of 159.74 J/g, and an elevated thermal decomposition temperature of 50° C. increase compared with that of the existing n-octadecane.

Classes IPC  ?

  • C01B 33/145 - Préparation d'hydro-organosols, d'organosols ou de dispersions dans un milieu organique

51.

USE OF PROTEIN SEQUENCE CAPABLE OF BINDING TO SUBSTRATE IN PREPARATION OF PRODUCT FOR INHIBITING FIBRIN ASSEMBLY

      
Numéro d'application CN2023127768
Numéro de publication 2024/093915
Statut Délivré - en vigueur
Date de dépôt 2023-10-30
Date de publication 2024-05-10
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE (Chine)
  • HUAZHONG AGRICULTURAL UNIVERSITY (Chine)
Inventeur(s)
  • Dong, Xianchi
  • Liu, Wen
  • Ding, Jianping
  • Shi, Yu
  • Xu, Shutong
  • Xu, Jianbo

Abrégé

Provided are a protein comprising an amino acid sequence capable of binding to a substrate GPRP peptide fragment, a fibrinogen like protein 1 (FGL1) comprising the amino acid sequence, and a fibrinogen domain (FD) thereof, and an individual FD protein has the same or similar function as the FGL1. The FGL1 and the FD can inhibit the assembly of fibrin in a thrombogenesis process by competing for a fibrin substrate-binding pocket. By means of mutations, the FGL1 and the FD can have stronger substrate affinity, such that the using effect of a thrombus treatment drug can be effectively enhanced.

Classes IPC  ?

  • C07K 14/745 - Facteurs de coagulation sanguine ou de fibrinolyse
  • C12N 15/12 - Gènes codant pour des protéines animales
  • C07K 1/22 - Chromatographie d'affinité ou techniques analogues basées sur des procédés d'absorption sélective
  • C07K 1/16 - ExtractionSéparationPurification par chromatographie
  • C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression
  • C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
  • A61K 38/36 - Facteurs de coagulation sanguine ou de fibrinolyse
  • A61K 38/49 - UrokinaseActivateur du plasminogène
  • A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
  • A61P 7/02 - Agents antithrombotiquesAnticoagulantsAnti-agrégants plaquettaires

52.

OPTICAL PHASED ARRAY DEVICE THAT CAN FLEXIBLY SET THE LIGHT SPLITTING WEIGHT AND HAS GOOD SCALABILITY

      
Numéro d'application 18501734
Statut En instance
Date de dépôt 2023-11-03
Date de la première publication 2024-05-09
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Jiang, Wei
  • Wu, Guihan

Abrégé

An optical phased array device, which can flexibly set the light splitting weight and has good scalability, includes a light splitting network, phase shifters, and emission units. Among them, the light splitting network of the device can set the optical power weight of the array element freely and has good scalability. The light splitting network of optical phased array consists of a series of basic elements, each of which can realize uniform or non-uniform light splitting of N channels. The light splitting network adopts a tree topology. The tree network structure can be freely designed, and the components used by the network nodes can also be freely selected. By freely designing the structure of the light splitting network and the components used by each node, the optical output distribution of the network can be set, so that the far field distribution of the optical phased array can be optimized.

Classes IPC  ?

  • G02B 27/00 - Systèmes ou appareils optiques non prévus dans aucun des groupes ,
  • G02B 6/28 - Moyens de couplage optique ayant des bus de données, c.-à-d. plusieurs guides d'ondes interconnectés et assurant un système bidirectionnel par nature en mélangeant et divisant les signaux

53.

METHOD FOR REGULATING THERMAL BOUNDARY CONDUCTANCE BETWEEN METAL AND INSULATOR

      
Numéro d'application 18285473
Statut En instance
Date de dépôt 2022-11-01
Date de la première publication 2024-05-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Nie, Yuefeng
  • Zang, Yipeng
  • Lu, Minghui
  • Yan, Xuejun
  • Di, Chen
  • Geng, Zhiming

Abrégé

Provided is a method for regulating a thermal boundary conductance between a metal and an insulator, including: arranging a metal on a surface of an insulator, a contact surface between the metal and the insulator being a boundary between the metal and the insulator; and the insulator including a ferroelectric, a piezoelectric, or a pyroelectric; applying an external electric field or stress to the ferroelectric, and adjusting a magnitude of the external electric field or stress, or an included angle between a direction of the external electric field or stress with the boundary to regulate the thermal boundary conductance; or applying a stress to the piezoelectric, and adjusting a magnitude of the stress, or an included angle between a direction of the stress with the boundary to regulate the thermal boundary conductancer; or adjusting a temperature of the pyroelectric to regulate the thermal boundary conductance.

Classes IPC  ?

  • H01B 3/00 - Isolateurs ou corps isolants caractérisés par le matériau isolantEmploi de matériaux spécifiés pour leurs propriétés isolantes ou diélectriques
  • H01B 1/02 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement de métaux ou d'alliages
  • H01B 3/10 - Isolateurs ou corps isolants caractérisés par le matériau isolantEmploi de matériaux spécifiés pour leurs propriétés isolantes ou diélectriques composés principalement de substances inorganiques oxydes métalliques
  • H01B 13/00 - Appareils ou procédés spécialement adaptés à la fabrication de conducteurs ou câbles
  • H01B 13/22 - GainageBlindageÉcransApplication de couches de protection d'un autre genre

54.

RNA PLASMID DELIVERY SYSTEM AND APPLICATION THEREOF

      
Numéro d'application 18374242
Statut En instance
Date de dépôt 2023-09-28
Date de la première publication 2024-05-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Chenyu
  • Chen, Xi
  • Fu, Zheng
  • Li, Jing
  • Zhang, Xiang
  • Zhou, Xinyan
  • Zhang, Li
  • Yu, Mengchao
  • Guo, Hongyuan

Abrégé

Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.

Classes IPC  ?

  • C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
  • A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
  • A61K 9/50 - Microcapsules
  • A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
  • C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains

55.

VIRAL VECTOR-BASED RNA DELIVERY SYSTEM AND USE THEREOF

      
Numéro d'application 18374253
Statut En instance
Date de dépôt 2023-09-28
Date de la première publication 2024-05-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Chenyu
  • Chen, Xi
  • Fu, Zheng
  • Li, Jing
  • Zhang, Xiang
  • Zhou, Xinyan
  • Zhang, Li
  • Yu, Mengchao
  • Guo, Hongyuan

Abrégé

Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.

Classes IPC  ?

  • C12N 15/86 - Vecteurs viraux
  • A61P 3/04 - AnorexigènesMédicaments de l'obésité
  • A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
  • A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p. ex. chorée, dyskinésie
  • A61P 35/00 - Agents anticancéreux
  • C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens

56.

MOUSE CELL, AND HUMANIZED MOUSE AND CONSTRUCTION METHOD THEREFOR AND USE THEREOF

      
Numéro d'application CN2023127313
Numéro de publication 2024/088412
Statut Délivré - en vigueur
Date de dépôt 2023-10-27
Date de publication 2024-05-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Li, Yan
  • Zhu, Rujie
  • Ren, Deshan
  • Ding, Shuai
  • Liu, Shuang

Abrégé

Disclosed are a TLR7-IFN I signaling pathway activated mouse in-vivo cell, a humanized systemic lupus erythematosus mouse having the cell, a construction method for the mouse, and a use of the mouse in medical research. Specifically, a TLR7-IFN I signaling pathway of a cell is activated by administering a TLR7 agonist Resiquimod, such that the mouse exhibits a similar phenotype of a patient with systemic lupus erythematosus, and a plasmid expressing human Flt3L and a DNA derived from autologous activated lymphocytes are injected into the mouse, such that the humoral immune response of B cells of the mouse is promoted, and B cell subpopulation imbalance and autoantibody generation are induced, thereby constructing the humanized systemic lupus erythematosus mouse. According to the humanized systemic lupus erythematosus mouse, immune disorders and corresponding phenotypes are induced in a human immune system, such that the humanized systemic lupus erythematosus mouse is more beneficial to screening a novel targeted drug.

Classes IPC  ?

  • C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
  • A01K 67/027 - Nouvelles races ou races modifiées de vertébrés
  • C12N 15/90 - Introduction stable d'ADN étranger dans le chromosome
  • C12N 15/12 - Gènes codant pour des protéines animales

57.

CONTAINER EQUIPMENT AND METHOD FOR ENCLOSED TRANSPORTATION AND HETEROTOPIC AND AEROBIC STABILIZATION OF RESERVED GARBAGE

      
Numéro d'application 18558030
Statut En instance
Date de dépôt 2022-04-28
Date de la première publication 2024-05-02
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • NANJING CROSS ENVIRONMENTAL TECHNOLOGY CO., LTD. (Chine)
Inventeur(s)
  • Wu, Jun
  • Chen, Yifan
  • Pan, Zhouzhi
  • Lv, Yiiian
  • Ma, Haitao
  • Zhu, Junwei
  • Yang, Zhiii
  • Li, Pinghai
  • Xue, Wangfeng

Abrégé

The present invention discloses a container equipment for enclosed transportation and heterotopic and aerobic stabilization of reserved garbage, which includes a container body and a functional lining provided on an inner wall of the container body, wherein the functional lining is provided with a circulating air low-temperature evaporation system, a water distribution and drainage system and a heating and insulating system; the circulating air low-temperature evaporation system includes an air inlet manifold, an air distribution perforated pipe, a base plate water discharge and air distribution groove and a top plate water distribution and air guide groove, an air extraction perforated pipe, a fan, an air outlet pipe and a quicklime dehydration and deodorization system; the water distribution and drainage system includes a percolate feeding pipe, a fiber capillary water distribution pipe, the top plate water distribution and air guide groove, a side drain, a main drain and a percolate discharge pipe; the heating and insulating system includes a base plate hydrothermal manifold, a bottom hydrothermal coil, a peripheral hydrothermal layer, a bottom air insulating layer and a peripheral air insulating layer. The present invention also discloses a method for using the container equipment described above. The present invention achieves a fully-enclosed transportation of solid waste and a heterotopic and aerobic stabilization process.

Classes IPC  ?

  • B65D 88/74 - Grands réceptacles comportant des moyens pour le chauffage, le refroidissement, l'aération ou un autre conditionnement du contenu
  • B65D 90/04 - Garnitures internes

58.

GENE CIRCUIT, RNA DELIVERY SYSTEM AND USE THEREOF

      
Numéro d'application 18374236
Statut En instance
Date de dépôt 2023-09-28
Date de la première publication 2024-05-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Chenyu
  • Chen, Xi
  • Fu, Zheng
  • Li, Jing
  • Zhang, Xiang
  • Zhou, Xinyan
  • Zhang, Li
  • Yu, Mengchao
  • Guo, Hongyuan

Abrégé

Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.

Classes IPC  ?

  • C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
  • A61K 31/7105 - Acides ribonucléiques naturels, c.-à-d. contenant uniquement des riboses liés à l'adénine, la guanine, la cytosine ou l'uracile et ayant des liaisons 3'-5' phosphodiester

59.

RNA DELIVERY SYSTEM FOR TREATMENT OF HUNTINGTON'S DISEASE

      
Numéro d'application 18477107
Statut En instance
Date de dépôt 2023-09-28
Date de la première publication 2024-05-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Chenyu
  • Chen, Xi
  • Fu, Zheng
  • Li, Jing
  • Zhang, Xiang
  • Zhou, Xinyan
  • Zhang, Li
  • Yu, Mengchao
  • Guo, Hongyuan

Abrégé

An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.

Classes IPC  ?

  • C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
  • A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
  • A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
  • C12N 15/86 - Vecteurs viraux

60.

HUMANIZED CELL, ANIMAL MODEL, AND CONSTRUCTION METHOD AND USE THEREFOR

      
Numéro d'application CN2023136175
Numéro de publication 2024/078643
Statut Délivré - en vigueur
Date de dépôt 2023-12-04
Date de publication 2024-04-18
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • GEMPHARMATECH CO., LTD (Chine)
Inventeur(s)
  • Li, Yan
  • Liu, Wei
  • Wang, Huiyi

Abrégé

Provided in the present invention are a genetically modified mouse cell, a mouse having a humanized immune system containing said mouse cell, and a construction method for the humanized mouse. The method comprises: inactivating a GFI1 gene on a mouse, and without sublethal irradiation, directly carrying out a humanized modeling process by injecting hematopoietic stem cells, wherein the dosage of the hematopoietic stem cells can be reduced to one eighth of an original reference dose.

Classes IPC  ?

  • C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
  • C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
  • C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales

61.

STRUCTURE OF TWO-DIMENSIONAL MATERIAL-BASED DEVICE HAVING AIR-GAP AND METHOD FOR PREPARING SAME

      
Numéro d'application 18505955
Statut En instance
Date de dépôt 2023-11-09
Date de la première publication 2024-03-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wang, Xinran
  • Fan, Dongxu
  • Li, Weisheng
  • Qiu, Hao
  • Shi, Yi

Abrégé

A structure of a two-dimensional material-based device having an air-gap and a method for preparing same comprises a substrate, a gate, an dielectric, a two-dimensional material-based film, and source and drain electrodes; the air-gap is formed between the two-dimensional material-based film and the side wall of the dielectric on the gate, or the air-gap is formed between the dielectric and the gate; two-dimensional material-based devices of the above structure utilize the ductility and flexibility of two-dimensional materials to reduce the coupling between the gate and the source/drain electrodes, thereby reducing the parasitic capacitance and the circuit delay; also, the structure ensures that a part of the contact region of the source and drain electrodes with the two-dimensional material can be controlled by the gate, and can thus avoid the reduction in electrical properties and keep a low resistance of the device.

Classes IPC  ?

62.

POLYCATIONIC POLYSACCHARIDE AND APPLICATION THEREOF

      
Numéro d'application 17791796
Statut En instance
Date de dépôt 2020-01-09
Date de la première publication 2024-03-21
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s) Dong, Lei

Abrégé

A polycationic polysaccharide and an application thereof is disclosed. Specifically, the polycationic polysaccharide consists of a polysaccharide and a polyamine compound, and is a positively charged polycationic polysaccharide obtained by reacting a polysaccharide with an amine-containing or polyamine compound. The polycationic polysaccharide is applied in a biomedical functional material of an antibacterial biofilm, a biomedical device, and an antibacterial functional material.

Classes IPC  ?

  • C08L 5/00 - Compositions contenant des polysaccharides ou leurs dérivés non prévus dans les groupes ou
  • A61K 31/715 - Polysaccharides, c.-à-d. ayant plus de cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiquesLeurs dérivés, p. ex. éthers, esters
  • A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine

63.

Preparation method and application of clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics

      
Numéro d'application 18511968
Numéro de brevet 12054404
Statut Délivré - en vigueur
Date de dépôt 2023-11-16
Date de la première publication 2024-03-14
Date d'octroi 2024-08-06
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • QUANZHOU INSTITUTE FOR ENVIRONMENTAL PROTECTION INDUSTRY, NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yang, Hu
  • Chang, Qianqian

Abrégé

A preparation method and an application of a clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics are provided, which relate to the field of water environment treatments. A clay/tannic acid/metal ion composite adsorbent is prepared, preparation method and operation process are simple, synthesis time is short, and yield is large. A raw material used is tannic acid, which has a wide range of sources, is non-toxic, biodegradable, and has no risk of secondary pollution, due to abundant phenolic hydroxyl groups in tannic acid, the tannic acid can not only chelate with the metal ions, but also adsorb pollutants from water, when combined with the clay and the metal ions, a composite body is formed, which has a rougher surface, and adsorption active sites are increased, thereby effectively increasing adsorption, and improving an adsorption performance for pollutants. The clay/tannic acid/metal ion composite adsorbent has good adsorption effect for antibiotics.

Classes IPC  ?

  • C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
  • B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
  • B01J 20/12 - Argiles d'origine naturelle ou terres décolorantes
  • B01J 20/24 - Composés macromoléculaires d'origine naturelle, p. ex. acides humiques ou leurs dérivés
  • B01J 20/30 - Procédés de préparation, de régénération ou de réactivation
  • C02F 101/38 - Composés organiques contenant de l'azote

64.

RECONSTRUCTION METHOD AND SYSTEM FOR WASTEWATER BIOLOGICAL TREATMENT PROCESS BASED ON MACHINE LEARNING SYSTEM

      
Numéro d'application 18480539
Statut En instance
Date de dépôt 2023-10-04
Date de la première publication 2024-03-14
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wang, Jinfeng
  • Hu, Jie
  • Ren, Hongqiang

Abrégé

It is disclosed a method and system based on machine learning for reconstructing biological wastewater treatment processes; the method includes: acquiring influent and effluent basic quality, ecological risk and process information data on the biological wastewater treatment process, and performing data preprocessing; performing feature extraction and multi-unit characterization on the biological wastewater treatment process; constructing effluent basic quality prediction models and effluent ecological risk prediction models of different biological treatment multi-unit combination processes, and performing standard-reaching validation; simulating and reconstructing different biological wastewater treatment short-range unit combination processes, and performing effluent quality standard-reaching validation under different influent quality scenarios; and evaluating ecological risk of the reconstructed short-range biological treatment unit combination processes with the effluent quality up to standard, and determining the optimal biological wastewater treatment process.

Classes IPC  ?

  • C02F 3/00 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout
  • C02F 3/30 - Procédés aérobies et anaérobies

65.

METHOD FOR MODIFYING DNA BY UTILIZING GLYCOSYLASE AND OXYAMINE COMPOUND

      
Numéro d'application 18273552
Statut En instance
Date de dépôt 2021-06-02
Date de la première publication 2024-03-07
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yu, Hanyang
  • Yang, Jintao
  • Li, Zhe

Abrégé

The present disclosure discloses a method for modifying a DNA by utilizing a glycosylase and an oxyamine compound, including the following steps: conducting solid phase synthesis of a DNA strand carrying a non-canonical base; reacting the DNA strand carrying a non-canonical base under the catalysis of the glycosylase which selectively recognizes the non-canonical base, to produce a DNA strand carrying an abasic site; and reacting the DNA strand carrying the abasic site with the oxyamine compound to generate a DNA modified with a chemical functional group. This method can realize diverse site-directed modification of the DNA, can be used to study the base structure-function relationship of a functional DNA, and construct a functional DNA with higher activity. The present method is simple and easy to use, and can reduce the cost and the time required for modification. The modified functional DNA has higher activity and can provide better tool molecules for biotechnology, disease diagnosis and treatment.

Classes IPC  ?

  • C12P 19/34 - Polynucléotides, p. ex. acides nucléiques, oligoribonucléotides
  • C12N 9/24 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2)

66.

THREE-DIMENSIONAL POROUS NANOCOMPOSITE COOLING FILM AND METHOD OF PREPARING THE SAME

      
Numéro d'application 17904285
Statut En instance
Date de dépôt 2021-11-29
Date de la première publication 2024-03-07
Propriétaire
  • Nanjing University (Chine)
  • Haian Institute of High-Tech Research, Nanjing University (Chine)
Inventeur(s)
  • Tang, Shaochun
  • Zhang, Rong
  • Xiang, Bo
  • Shen, Yuchun

Abrégé

Disclosed is a method for preparing a three-dimensional porous nano composite cooling film in large scale. The cooling film is prepared from 0.1-0.5 parts of cellulose acetate, 1-5 parts of water, 20-100 parts of acetone, an additive, and 10-20 parts of nano microspheres through a cooperative formulation of cellulose acetate, nano microsphere materials and the additive. The composite cooling film is obtained by self-deposition of cellulose acetate and nano microspheres, and liquid volatilization during film forming process leads to formation of the three-dimensional porous structure. The film has an effect of enhancing radiation of infrared heat into space, which could significantly reduce a temperature of a substrate surface and achieve rapid and strong cooling. The film could achieve effective cooling without external power and other active cooling equipment, with or without sunlight.

Classes IPC  ?

  • C04B 26/28 - Polysaccharides ou leurs dérivés
  • B29C 39/00 - Moulage par coulée, c.-à-d. en introduisant la matière à mouler dans un moule ou entre des surfaces enveloppantes sans pression significative de moulageAppareils à cet effet
  • C04B 20/00 - Emploi de matières comme charges pour mortiers, béton ou pierre artificielle prévu dans plus d'un groupe et caractérisées par la forme ou la répartition des grainsTraitement de matières spécialement adapté pour renforcer leur propriétés de charge dans les mortiers, béton ou pierre artificielle prévu dans plus d'un groupe de Matières expansées ou défibrillées
  • C04B 38/00 - Mortiers, béton, pierre artificielle ou articles de céramiques poreuxLeur préparation
  • C04B 40/00 - Procédés, en général, pour influencer ou modifier les propriétés des compositions pour mortiers, béton ou pierre artificielle, p. ex. leur aptitude à prendre ou à durcir

67.

PHOTORESIST-FREE OPTICAL PATTERNING METHOD FOR COLLOIDAL NANOCRYSTALS IN GREEN SOLVENT

      
Numéro d'application CN2023078990
Numéro de publication 2024/045525
Statut Délivré - en vigueur
Date de dépôt 2023-03-01
Date de publication 2024-03-07
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wang, Yuanyuan
  • Xiao, Pengwei
  • Zhang, Zhoufan
  • Luo, Huanhuan

Abrégé

The present invention relates to the technical field of nanomaterials and optical etching, and provides a photoresist-free optical patterning method for colloidal nanocrystals in a green solvent. A photosensitive ligand structurally similar to the green solvent is introduced to successfully disperse nanocrystals in the green solvent and perform photolithography directly on the nanocrystals. Photosensitive nanocrystals obtained through ligand exchange can be effectively dispersed in the green solvent to absorb an emission spectrum emitted by the green solvent, thereby preserving about 90% of photoluminescence quantum yield (PLQY) while keeping the morphology and size unchanged. The scheme solves the problem that nanocrystals cannot be subject to direct photolithography in the green solvent, and is expected to be applied to the commercialization of nanocrystals in the field of electroluminescent and photoluminescent quantum dot displays.

Classes IPC  ?

  • G03F 7/027 - Composés photopolymérisables non macromoléculaires contenant des doubles liaisons carbone-carbone, p. ex. composés éthyléniques
  • G03F 7/004 - Matériaux photosensibles

68.

SOLAR BATTERY

      
Numéro d'application 18450619
Statut En instance
Date de dépôt 2023-08-16
Date de la première publication 2024-02-22
Propriétaire
  • Trina Solar Co., Ltd. (Chine)
  • Nanjing University (Chine)
Inventeur(s)
  • Tan, Hairen
  • Xia, Rui
  • Li, Hongjiang
  • Luo, Haowen
  • Zhang, Xueling
  • Xu, Guanchao
  • Chen, Yifeng

Abrégé

The present disclosure relates to a solar battery including a first cell, and a second cell, and a first charge transport layer, a transparent conductive layer, a second charge transport layer and a polysilicon layer are disposed between the first photoelectric conversion layer of the first cell and the second photoelectric conversion layer of the second cell, and the second charge transport layer is disposed between the polysilicon layer and the transparent conductive layer, and the charge transport property of the second charge transport layer is the same as that of the polysilicon layer. In the solar battery of the present disclosure, a first charge transport layer, a transparent conductive layer, a second charge transport layer and a polysilicon layer are sequentially arranged between the first photoelectric conversion layer and the second photoelectric conversion layer. Especially the second charge transport layer may protect the polysilicon layer, may effectively transport the same type of charges, and avoid recombination phenomena at the interface or inside the film, thereby effectively improving the efficiency of the battery. The solar battery of this disclosure also has the characteristics of simple structure, simple and convenient manufacturing process, and low cost.

Classes IPC  ?

  • H10K 30/57 - Dispositifs photovoltaïques [PV] comprenant des jonctions multiples, p. ex. des cellules PV en tandem
  • H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n

69.

DEVICE AND METHOD FOR PARALLELIZING ANALOG IN-MEMORY COMPUTING BASED ON FREQUENCY DIVISION MULTIPLEXING

      
Numéro d'application 17763515
Statut En instance
Date de dépôt 2021-05-31
Date de la première publication 2024-02-15
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Miao, Feng
  • Liang, Shijun
  • Wang, Cong

Abrégé

A device for parallelizing analog in-memory computing based on frequency division multiplexing comprises an input circuit, a memory array and an output circuit, wherein an input of the memory array is connected with an output of the input circuit, and an output of the memory array is connected with an input of the output circuit; the input circuit modulates k data in each row of m×k input data matrix into each path of frequency division multiplexing signals for output by using k different frequency sources; the memory array comprises m×n memory elements, memory weights thereof form an m×n matrix, and m×1 input frequency division multiplexing signals are parallel-processed in the memory array; and the output circuit demodulates and separates each path of frequency division multiplexing signals output by the memory array into k data.

Classes IPC  ?

70.

ECL-BASED ELECTRODE, MANUFACTURING METHOD FOR ECL-BASED ELECTRODE, ECL SENSOR, MANUFACTURING METHOD FOR ECL SENSOR, METHOD FOR ECL DETECTION OF NUCLEIC ACID-SPECIFIC SITE MODIFICATION, AND KIT FOR NUCLEIC ACID MODIFICATION DETECTION USED FOR METHOD FOR ECL DETECTION OF NUCLEIC ACID-SPECIFIC SITE MODIFICATION

      
Numéro d'application 18361335
Statut En instance
Date de dépôt 2023-07-28
Date de la première publication 2024-02-08
Propriétaire
  • CANON MEDICAL SYSTEMS CORPORATION (Japon)
  • Nanjing University (Chine)
Inventeur(s)
  • Huang, Hao
  • Xu, Qiqi
  • Wu, Xiaotian
  • Ju, Huangxian
  • Wu, Jie

Abrégé

A manufacturing method for an ECL (Electrochemiluminescence)-based electrode according to an embodiment includes a step of mixing an electrocatalytic solution and metal nanoparticles and thereafter dropping a mixed particle suspension onto the surface of an electrode and obtaining a base electrode co-modified by an electrocatalyst-metal nanoparticle.

Classes IPC  ?

  • G01N 21/66 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité électriquement, p. ex. par électroluminescence
  • G01N 21/76 - ChimioluminescenceBioluminescence
  • G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

71.

DISTRIBUTED WEAK GRATING ARRAY SENSING SYSTEM AND METHOD WITH MULTIPLE DEMODULATION MODES

      
Numéro d'application 18116856
Statut En instance
Date de dépôt 2023-03-03
Date de la première publication 2024-02-01
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wang, Feng
  • Hong, Rui
  • Zhang, Xuping
  • Zhang, Yixin

Abrégé

A distributed weak grating array sensing system and method with multiple demodulation modes are provided for optical fiber sensing. The distributed weak grating array sensing method includes: amplitude modulating, by an acousto-optic modulator, a laser light to form a double-pulse light satisfying a preset requirement; linearly phase modulating, by a phase modulator, a phase of front pulse light or rear pulse light of the double-pulse light; amplifying double-pulse light after amplitude modulation and phase modulation, and introducing the double-pulse light into a grating array; allowing reflected light of the double-pulse light on adjacent gratings to superimpose and form interference light; introducing the interference light into a photoelectric detector; acquiring, by an acquisition card, data; locating a disturbance through the amplitude fluctuation; accurately acquiring a sampling number corresponding to 2π; and selecting π/2 phase difference demodulation, 2π/3 phase difference demodulation, π/4 phase difference demodulation, proposed N-step phase difference demodulation as required.

Classes IPC  ?

  • H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
  • H01S 3/067 - Lasers à fibre optique
  • G02F 1/11 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des éléments acousto-optiques, p. ex. en utilisant la diffraction variable par des ondes sonores ou des vibrations mécaniques analogues
  • G01H 9/00 - Mesure des vibrations mécaniques ou des ondes ultrasonores, sonores ou infrasonores en utilisant des moyens sensibles aux radiations, p. ex. des moyens optiques

72.

Method and system for intelligent source tracing of organic pollution of water body

      
Numéro d'application 18005565
Numéro de brevet 11965871
Statut Délivré - en vigueur
Date de dépôt 2022-02-24
Date de la première publication 2024-01-25
Date d'octroi 2024-04-23
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Wu, Jichun
  • Liu, Mengwen
  • Wei, Si
  • Zhu, Xiaobin
  • Yu, Nanyang

Abrégé

Disclosed are a method and system for intelligent source tracing of organic pollution of a water body, which belongs to the technical field of environmental analytical chemistry. The method comprises: acquiring organic matter analysis and detection data from water samples of a polluted water body through high performance liquid chromatography-tandem mass spectrometry; performing high-throughput screening on the organic matter in the water samples according to said data to determine pollutants; identifying pollution sources by means of network analysis according to the determined pollutants; and according to the identified pollution sources and the organic pollutants, determining key pollutants and quantifying the pollution contributions thereof by using a machine learning classification model. The present invention can achieve intelligent tracing of the pollution sources and the key pollutants thereof in the case of the pollution sources being unknown, and provide technical support for investigation and control of organic pollution in a water environment.

Classes IPC  ?

73.

INTERFACIAL ADSORPTION METHOD FOR EFFICIENTLY REMOVING PERFLUORINATED COMPOPUNDS FROM WATER BODY

      
Numéro d'application CN2023106500
Numéro de publication 2024/012391
Statut Délivré - en vigueur
Date de dépôt 2023-07-10
Date de publication 2024-01-18
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Gu, Cheng
  • Chen, Zhanghao
  • Huang, Liuqing
  • Teng, Ying

Abrégé

An interfacial adsorption method for efficiently enriching perfluorinated compounds in a water body, the interfacial adsorption method comprising the steps of: mixing a polluted water body containing a perfluorinated compound, a long-carbon-chain cationic surfactant and a water-insoluble oil substance to obtain an oil-water mixture of an oil phase and a water phase, which mixture contains the perfluorinated compound and the cationic surfactant; and leaving the oil-water mixture to stand for adsorption. By introducing a long-carbon-chain cationic surfactant onto an oil-water interface, the cationic surfactant is tightly combined with an anionic perfluorinated compound by means of electrostatic interaction, such that an active interface with an electron attracting capability is constructed, and efficient enrichment and removal of the perfluorinated compound on the interface are realized.

Classes IPC  ?

  • C02F 1/26 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par extraction
  • C02F 101/14 - Fluor ou composés fluorés

74.

Identification method of urban functional areas based on mixing degree of functions and integrated learning

      
Numéro d'application 18031009
Numéro de brevet 12033043
Statut Délivré - en vigueur
Date de dépôt 2022-07-01
Date de la première publication 2024-01-11
Date d'octroi 2024-07-09
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Chen
  • Xu, Yunyun
  • Chen, Zhenjie
  • Li, Manchun
  • Zhao, Xin
  • Yu, Zhixin
  • Du, Haoyang
  • Wen, Boqing
  • Wang, Zian
  • Xia, Nan

Abrégé

An identification method of urban functional areas based on mixing degree of functions and integrated learning includes the following steps: 1) performing data acquisition and preprocessing; 2) constructing 10 indicator features of an urban functional area identification system; 3) structuring the indicator features: acquiring, by a spatial statistical tool, the 10 indicator features corresponding to each parcel; 4) constructing an independent variable dataset; 5) labeling response variables; 6) dividing a training dataset into a plurality of training subsets according to the mixing degree of functions; 7) training a Stacking-based integrated learning model; and 8) joining an attribute in one table to another table, so as to complete the identification of the urban functional areas on each parcel. The identification method divides the training dataset by grading the mixing degree of functions, and makes predictions based on the prediction dataset with corresponding mixing degree of functions.

Classes IPC  ?

75.

ARTIFICIAL BOARD AND PREPARATION METHOD THEREFOR

      
Numéro d'application CN2022105622
Numéro de publication 2024/007359
Statut Délivré - en vigueur
Date de dépôt 2022-07-14
Date de publication 2024-01-11
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhu, Mingwei
  • Huang, Zhonglei
  • Chen, Yanfeng

Abrégé

An artificial board and a preparation method therefor. The preparation method comprises the following steps: activating plant fibers with a non-derivatized solvent to obtain a plant fiber solution, wherein the plant fibers are wall-broken or non-wall-broken plant cells; then mixing the plant fiber solution with plant particles until uniform, and molding same; and then subsequently subjecting same to a drying treatment, a soaking and cleaning treatment and a standing treatment, so as to obtain an artificial board. In the method, plant particles and activated plant fibers are cross-linked by means of hydrogen bonds to prepare an artificial board, a resin adhesive does not need to be used, and toxicity and harm are avoided during the production and use processes. Moreover, since a large number of hydroxyl groups are exposed after the plant fibers in the plant fiber solution are subjected to an activating treatment, stronger cross-linking between the plant fibers and the plant particles are more easily realized, and therefore the artificial board is endowed with good mechanical properties.

Classes IPC  ?

  • B27N 3/12 - Moulage des mats à partir de fibres
  • B27N 3/18 - Opérations auxiliaires, p. ex. préchauffage, humidification, coupe

76.

THREE-DIMENSIONAL (3D) RECONSTRUCTION DEVICE AND METHOD OF FLAME SPECTRA

      
Numéro d'application 18251410
Statut En instance
Date de dépôt 2021-05-12
Date de la première publication 2023-12-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Cao, Xun
  • Cai, Lijing
  • Zhang, Yan
  • Liu, Zhengyu
  • Wang, Chen

Abrégé

A three-dimensional (3D) reconstruction device and a method of flame spectra are provided. The device has a plurality of prism-mask shooting systems and a plurality of mirrors. The prism-type shooting systems are set up around a combustion area to be reconstructed and each is provided with two mirrors which are tilted on the left and right of an axis of the shooting system, so that data of a flame are reflected by the mirrors into the prism-mask shooting systems, thus realizing the real-time acquisition of hyperspectral data of the flame from multiple shooting angles. The reconstruction method includes following steps of acquiring, by a calibration cylinder, an area to be reconstructed, synchronously acquiring and preprocessing hyperspectral data of a flame, and finally reconstructing 3D spectral data of the flame by a 3D reconstruction algorithm of flame spectra.

Classes IPC  ?

  • H04N 13/282 - Générateurs de signaux d’images pour la génération de signaux d’images correspondant à au moins trois points de vue géométriques, p. ex. systèmes multi-vues
  • G06T 5/00 - Amélioration ou restauration d'image
  • G06T 15/00 - Rendu d'images tridimensionnelles [3D]

77.

RICE PRODUCTION POTENTIAL SIMULATION METHOD BASED ON LAND SYSTEM AND CLIMATE CHANGE COUPLING

      
Numéro d'application CN2022100006
Numéro de publication 2023/245399
Statut Délivré - en vigueur
Date de dépôt 2022-06-21
Date de publication 2023-12-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Li, Manchun
  • Jiang, Penghui
  • Du, Cong

Abrégé

A rice production potential simulation method based on land system and climate change coupling, the method comprising the following steps: constructing a GM-FLUS model to simulate a change of a land system (S1); using a GAEZ model to estimate rice production potential (S2); and analyzing spatial distribution features and time change trends of the rice production potential in different scenarios (S3). By means of constructing a GM-FLUS model to simulate a change of a land system, in view of four future climate scenarios of SSP1-2.6, SSP2-4.5, SSP3-7.0 and SSP5-8.5 among shared socioeconomic pathways (SSPs) under a CAS-ESM2 climate scenario model intercomparison project, and by using a GAEZ model to take various factors such as climate, soil, terrain, a land system, etc., into consideration, rice production potential is estimated, thereby providing a technical support for coping with a future climate change, rationally using cultivated land resources and guaranteeing food security.

Classes IPC  ?

  • G06F 111/08 - CAO probabiliste ou stochastique
  • G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
  • G06N 5/04 - Modèles d’inférence ou de raisonnement

78.

POROUS AMINATED ORGANIC FLUORINE CAPSULE, PREPARATION METHOD THEREFOR AND USE THEREOF

      
Numéro d'application CN2023100648
Numéro de publication 2023/241689
Statut Délivré - en vigueur
Date de dépôt 2023-06-16
Date de publication 2023-12-21
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Gu, Cheng
  • Chen, Zhanghao
  • Teng, Ying

Abrégé

A porous aminated organic fluorine capsule, a preparation method therefor and a use thereof. The porous aminated organic fluorine capsule comprises a porous organic fluorine shell, and an aminated phenolic resin is filled in the organic fluorine shell. On the basis of a common polyvinylidene fluoride membrane material, a polyvinylpyrrolidone pore-forming agent, and the aminated phenolic resin, a porous organic fluorine capsule material is synthesized by a solvent displacement method; under a synergistic effect of the organic fluorine shell of the capsule and the internal aminated phenolic resin, efficient and selective removal of an anionic perfluorinated compound is successfully achieved; and moreover, the raw materials are cheap and readily available, and the preparation is simple and convenient.

Classes IPC  ?

  • C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
  • B01D 71/34 - Fluorure de polyvinylidène
  • B01J 20/26 - Composés macromoléculaires synthétiques

79.

PROGRAMMABLE NANO-REACTORS FOR STOCHASTIC SENSING (PNRSS)

      
Numéro d'application 18252672
Statut En instance
Date de dépôt 2021-07-22
Date de la première publication 2023-12-14
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Huang, Shuo
  • Jia, Wendong

Abrégé

A system and a method for characterizing a target analyte are provided. The system comprises a nanopore and a polymer strand comprising a tether site and a reaction section, wherein the polymer strand is tethered via the tether site so that the polymer strand cannot pass through the nanopore, and wherein the reaction section comprises at least one sensing module which can interact with single molecule of the target analyte.

Classes IPC  ?

  • G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques
  • G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
  • G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

80.

Method for assessing microbial drug resistance multi-level risks of antibiotic residues in water environment

      
Numéro d'application 18324954
Numéro de brevet 11959122
Statut Délivré - en vigueur
Date de dépôt 2023-05-27
Date de la première publication 2023-12-07
Date d'octroi 2024-04-16
Propriétaire
  • NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES, MEE (Chine)
  • NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Guo, Xinyan
  • Wang, Na
  • Yuan, Qingbin
  • Ni, Ni
  • Zhang, Xiaohui
  • Shi, Mali
  • Li, Jingbiao

Abrégé

A method for assessing microbial drug resistance multi-level risks of antibiotic residues in water environments, belonging to the technical field of water environment assessment, comprises the following steps: S1, environment monitoring; S2, preliminary screening of antibiotics: S2-1, determination of n-octanol/water partition coefficient, and S2-2, determination of antibiotic environment concentration; S3, assessment of microbial drug resistance; and S4, high-level assessment. The assessment method of the present disclosure conducts a step-by-step assessment of target antibiotics or target antibiotic derivatives in water environment with risks.

Classes IPC  ?

  • C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
  • A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
  • A61P 31/04 - Agents antibactériens
  • C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries

81.

DEVICE FOR SYNTHESIZING HOMOGENEOUS POLYMER SPHERES BASED ON CHANNEL PREPOLYMERIZATION, AND METHOD OF USING THE SAME

      
Numéro d'application 18148470
Statut En instance
Date de dépôt 2022-12-30
Date de la première publication 2023-12-07
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Shuang, Chendong
  • Chen, Dong
  • Zhong, Kaiwen
  • Zhang, Ziwei
  • Yang, Hongyu
  • Zhou, Weiwei
  • Li, Aimin

Abrégé

A homogeneous polymer sphere synthesis device based on channel prepolymerization comprises a jet vibrator, a spiral prepolymerization channel, a reactor and a water phase circulating system; two ends of the water phase circulating system are connected to the reactor and the spiral prepolymerization channel through pipes, respectively; the jet vibrator comprises a jet oil phase tank, a jet micropore plate and a vibration exciter for outputting vibration; the jet micropore plate is arranged in the jet oil phase tank; an outlet end of the spiral prepolymerization channel is connected to the reactor, while an inlet end thereof is connected to the jet oil phase tank.

Classes IPC  ?

  • B01J 19/24 - Réacteurs fixes sans élément interne mobile
  • B01J 19/06 - Solidification de liquides
  • B01J 19/00 - Procédés chimiques, physiques ou physico-chimiques en généralAppareils appropriés
  • C08F 212/08 - Styrène

82.

ELECTROCHEMILUMINESCENT NANOPROBE, PREPARATION METHOD THEREOF, ELECTROCHEMILUMINESCENCE DETECTION METHOD FOR NUCLEIC ACID SPECIFIC SITE MODIFICATION, KIT FOR ELECTROCHEMILUMINESCENCE DETECTION METHOD USING ANTIBODY, AND NANOPARTICLE FOR ELECTROCHEMILUMINESCENT NANOPROBE

      
Numéro d'application 18325445
Statut En instance
Date de dépôt 2023-05-30
Date de la première publication 2023-11-30
Propriétaire
  • CANON MEDICAL SYSTEMS CORPORATION (Japon)
  • NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Huang, Hao
  • Xu, Qiqi
  • Wu, Xiaotian
  • Ju, Huangxian
  • Wu, Jie

Abrégé

A method for preparing an electrochemiluminescent nanoprobe according to an embodiment includes: adding a metal complex ion to an inorganic oxide nanoparticle to provide a metal-doped inorganic oxide nanoparticle; and binding a secondary antibody to the metal-doped inorganic oxide nanoparticle to provide a metal-doped inorganic oxide nanoparticle modified with the secondary antibody. The secondary antibody is configured to identify a specific antibody against nucleic acid-specific site modification.

Classes IPC  ?

  • G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
  • B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
  • G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées

83.

LOW-CARBON AND HIGH-EFFICIENCY IN-SITU RAPID ENRICHMENT AND SEPARATION APPARATUS AND METHOD FOR LARGE-VOLUME WATER SAMPLE

      
Numéro d'application CN2023106271
Numéro de publication 2023/227140
Statut Délivré - en vigueur
Date de dépôt 2023-07-07
Date de publication 2023-11-30
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Qing
  • Wang, Xingyu
  • Zhang, Ruixiang
  • Zhang, Chunfeng
  • Xu, Yuqian
  • He, Xinyi
  • Zhang, Libin

Abrégé

The present invention relates to the field of water sample pretreatment apparatuses. Disclosed are a low-carbon and high-efficiency in-situ rapid enrichment and separation apparatus and method for a large-volume water sample. According to the present invention, by means of optimization of the shape structure of the apparatus in combination with dynamic collection of magnetic materials, a static settling process is eliminated, so that the problems that the magnetic materials are slow in settling velocity and prone to loss are solved, and the enrichment and separation efficiency of the magnetic materials is improved; moreover, such a low-carbon and energy-consumption-free operation mode has important application prospects in sampling processes in the field, especially in remote areas.

Classes IPC  ?

  • G01N 1/28 - Préparation d'échantillons pour l'analyse
  • G01N 1/40 - Concentration des échantillons
  • C02F 1/26 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par extraction
  • B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques

84.

PHOTOCATALYTIC MATERIAL FOR DEGRADING PYRIDINE, MODIFIED PHOTOCATALYTIC FILLER, AND PREPARATION METHODS THEREFOR AND USE THEREOF

      
Numéro d'application CN2023106270
Numéro de publication 2023/222142
Statut Délivré - en vigueur
Date de dépôt 2023-07-07
Date de publication 2023-11-23
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Qing
  • Chen, Yurong
  • Wang, Xin
  • Lei, Chongtian
  • Zhang, Ziang
  • Chen, Junxia
  • Zhou, Weiwei

Abrégé

344344 photocatalytic material, wherein the gradient hydrothermal reaction comprises: heating same to 155-165°C, maintaining the temperature for at least 2 h, heating same to 175-185°C, maintaining the temperature for at least 8 h, finally heating same to 210-230°C, and maintaining the temperature for at least 2 h, the heating rate being 1-3°C/min. In the present invention, the photocatalytic performance and recyclability of bismuth vanadate can be effectively improved, and when a porous filler is coated with bismuth vanadate, pyridine having concentrations of 100 mg/L and 500 mg/L can be completely mineralized and removed within 24 hours and 48 h, respectively.

Classes IPC  ?

85.

FE2O3-MXENE COMPOSITE CATALYST, AND PREPARATION METHOD THEREFOR AND USE THEREOF

      
Numéro d'application CN2023106272
Numéro de publication 2023/222143
Statut Délivré - en vigueur
Date de dépôt 2023-07-07
Date de publication 2023-11-23
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhou, Qing
  • Chen, Junxia
  • Zhang, Ziang
  • Li, Weigang
  • Chen, Yurong
  • Lei, Chongtian
  • Zhou, Weiwei

Abrégé

2332x32xx-MXene with an iron ion salt and an organic ligand for a reaction, wherein the organic ligand can be coordinated with Fe3+233-MXene composite catalyst. In the present invention, the problems of ferric oxide prepared by a traditional method being prone to agglomeration and having a poor electron transfer performance and a poor stability are solved, tetracycline in persulfate degradation wastewater can be fully activated, and the method has the advantages of a high efficiency, a high use value, ease of catalyst recovery, etc., and has great application prospects.

Classes IPC  ?

86.

FENTON-LIKE CATALYST MATERIAL WITH ELECTRON-POOR Cu CENTER, AND PREPARATION METHOD AND USE THEREOF

      
Numéro d'application 18028229
Statut En instance
Date de dépôt 2021-08-24
Date de la première publication 2023-11-23
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • NANJING UNIVERSITY & YANCHENG ACADEMY OF ENVIRONMENTAL PROTECTION TECHNOLOGY AND ENGINEERING (Chine)
  • NANHUAN YANCHENG ENVIRONMENTAL PROTECTION TECHNOLOGY CO., LTD. (Chine)
Inventeur(s)
  • Wang, Jinnan
  • Xie, Zhiqun
  • Chen, Lifang
  • Zhou, Jiali
  • Lyu, Zhiping
  • Li, Aimin

Abrégé

A Fenton-like catalyst material with an electron-poor Cu center and a preparation method and use thereof are provided. The preparation method includes: step 1: dissolving bismuth nitrate pentahydrate in a nitric acid solution and diluting a resulting solution with deionized water to obtain a solution A; step 2: adding citric acid to the solution A and adjusting a pH of a resulting solution with ammonia water to obtain a solution B; step 3: dissolving aluminium isopropoxide (AIP), copper chloride dihydrate, and glucose in the solution B to obtain a suspension C; step 4: stirring the suspension C at a high temperature to allow evaporation until a solid D is completely precipitated; and step 5: subjecting the solid D to calcination in a muffle furnace to obtain the Fenton-like catalyst material. Under neutral conditions, the catalyst material exhibits a prominent removal effect for various toxic organic pollutants, especially for phenolic pollutants.

Classes IPC  ?

87.

PHOTOCATALYTIC MATERIAL FOR EFFICIENT PHOTOCATALYTIC REMOVAL OF HIGH-CONCENTRATION NITRATE, AND PREPARATION METHOD AND USE THEREOF

      
Numéro d'application 18028243
Statut En instance
Date de dépôt 2021-08-24
Date de la première publication 2023-11-23
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • NANHUAN YANCHENG ENVIRONMENTAL PROTECTION TECHNOLOGY CO., LTD. (Chine)
  • NANJING UNIVERSITY & YANCHENG ACADEMY OF ENVIRONMENTAL PROTECTION TECHNOLOGY AND ENGINEERING (Chine)
Inventeur(s)
  • Wang, Jinnan
  • Hou, Zhiang
  • Bian, Weilin
  • Wang, Yi
  • Chu, Jiangfeng
  • Liu, Cong

Abrégé

A photocatalytic material for efficient photocatalytic removal of a high-concentration nitrate, and a preparation method and use thereof are disclosed. The preparation method includes the following steps: step 1: preparation of a citrate-stabilized silver nanoparticle; step 2: synthesis and functionalization modification of SiO2 step 3: preparation of Ag/SiO2; and step 4: preparation of an Ag/SiO2@cTiO2 core-shell structure. The photocatalytic material prepared by the present disclosure has high reduction catalytic activity and can quickly remove a high-concentration nitrate and achieve high nitrogen selectivity. In addition, due to protection of a titanium dioxide shell, the photocatalytic material has excellent stability and can remove a high-concentration nitrate in water when the nitrate coexists with a high-concentration chloride ion.

Classes IPC  ?

  • B01J 35/00 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général
  • B01J 23/50 - Argent
  • B01J 37/10 - Traitement thermique en présence d'eau, p. ex. de vapeur d'eau
  • C02F 1/30 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par irradiation

88.

Time delay integration (TDI)-based image sensor and imaging method thereof

      
Numéro d'application 18026547
Numéro de brevet 12149846
Statut Délivré - en vigueur
Date de dépôt 2021-09-15
Date de la première publication 2023-10-26
Date d'octroi 2024-11-19
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Mao, Cheng
  • Kong, Xiangshun
  • Yan, Feng

Abrégé

Disclosed are a time delay integration (TDI)-based image sensor and an imaging method thereof. The TDI-based image sensor includes: a multi-stage linear array including a plurality of single-stage linear arrays arranged along a scanning direction of the image sensor. Each single-stage linear array includes a plurality of pixels arranged along the linear array direction. Each single-stage linear array enters a count mode in response to a first control signal, and enters a transfer mode in response to a second control signal. In the count mode, each single-stage linear array counts optical signals incident on the pixels and obtains a count value, and in the transfer mode, each single-stage linear array stops counting, except for the last single-stage linear array, other single-stage linear arrays each output the obtained current count value to the next single-stage linear array, and the last single-stage linear array outputs the obtained current count value.

Classes IPC  ?

  • H04N 25/711 - Registres à report et intégration [TDI]Registres à décalage TDI
  • H04N 25/71 - Capteurs à dispositif à couplage de charge [CCD]Registres de transfert de charge spécialement adaptés aux capteurs CCD
  • H04N 25/74 - Circuits de balayage ou d'adressage de la matrice de pixels
  • H04N 25/75 - Circuits pour fournir, modifier ou traiter des signaux d'image provenant de la matrice de pixels
  • H04N 25/773 - Circuits de pixels, p. ex. mémoires, convertisseurs A/N, amplificateurs de pixels, circuits communs ou composants communs comprenant des convertisseurs A/N, V/T, V/F, I/T ou I/F comprenant des circuits de comptage de photons, p. ex. des diodes de détection de photons uniques [SPD] ou des diodes à avalanche de photons uniques [SPAD]

89.

PROCESS METHOD FOR FULL-SCALE RESOURCE UTILIZATION OF KITCHEN WASTE USING HERMETIA ILLUCENS AND AEROBIC MICROORGANISMS

      
Numéro d'application CN2022095814
Numéro de publication 2023/197421
Statut Délivré - en vigueur
Date de dépôt 2022-05-28
Date de publication 2023-10-19
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • LISHUI INSTITUTE OF ECOLOGICAL ENVIRONMENT, NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yuan, Zengwei
  • Cheng, Mingjin
  • Cheng, Xiang
  • Zhang, Shiwen

Abrégé

Provided in the present application is a process method for full-scale resource utilization of kitchen waste using Hermetia illucens and aerobic microorganisms. The method comprises: firstly, performing solid-liquid separation on kitchen waste; then performing quality-based resource utilization on the separated filtrate containing oils and salts and kitchen waste filter residues, and feeding young Hermetia illucens and 2nd-6th instar Hermetia illucens larvae respectively, so that the salts in the filtrate are transformed into the body fluid of the Hermetia illucens at the larval stage; separating the larval bodies and the larval residues in a timely manner so as to reduce the salinity of the larval feces and improve the transabdominal transformation efficiency of Hermetia illucens and the quality of the larval feces as a fertilizer; and finally, achieving the full-scale resource utilization of kitchen waste by means of aerobic composting and the dry sterilization of the larval bodies. According to the present invention, by synergistically utilizing the principles of transabdominal transformation by Hermetia illucens and degradation by aerobic microorganisms for the first time, the full-scale resource utilization of kitchen waste is achieved, and the problems of the high-salt wastewater in the existing transformation process being difficult to treat, the salt content of a fertilizer being too high to be used as a resource, and the nitrogen loss in the transformation process being severe are overcome.

Classes IPC  ?

  • C05F 17/05 - Traitements impliquant des invertébrés, p. ex. des vers, des mouches ou des asticots
  • C05F 9/00 - Engrais fabriqués à partir des ordures ménagères ou de ville

90.

Hermetia illucens L. and aerobic microorganisms

      
Numéro d'application 18308685
Numéro de brevet 11905224
Statut Délivré - en vigueur
Date de dépôt 2023-04-28
Date de la première publication 2023-10-19
Date d'octroi 2024-02-20
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • LISHUI INSTITUTE OF ECOLOGICAL ENVIRONMENT, NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Yuan, Zengwei
  • Cheng, Mingjin
  • Cheng, Xiang
  • Zhang, Shiwen

Abrégé

Hermetia illucens L. and quality of the insect manure; and finally implementing full resource utilization through aerobic composting and insect drying and sterilization treatment.

Classes IPC  ?

  • C05F 17/05 - Traitements impliquant des invertébrés, p. ex. des vers, des mouches ou des asticots
  • B09B 3/80 - Destruction de déchets solides ou transformation de déchets solides en quelque chose d'utile ou d'inoffensif impliquant une étape d'extraction
  • B09B 3/30 - Destruction de déchets solides ou transformation de déchets solides en quelque chose d'utile ou d'inoffensif impliquant un traitement mécanique
  • A01K 67/033 - NÉCESSITÉS COURANTES DE LA VIE ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE ÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux Élevage ou obtention d'invertébrés; Nouvelles races d'invertébrés

91.

Self-heterodyne φ-OTDR system with free multi-spatial resolution

      
Numéro d'application 17920809
Numéro de brevet 11860008
Statut Délivré - en vigueur
Date de dépôt 2022-05-06
Date de la première publication 2023-10-05
Date d'octroi 2024-01-02
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Yixin
  • Song, Jinyu
  • Zhang, Xuping
  • Ding, Zhewen
  • Tong, Shuai
  • Wang, Shun
  • Wang, Feng

Abrégé

A self-heterodyne phase-sensitive optical time domain reflectometry (φ-OTDR) system with a free multi-spatial resolution includes a narrow linewidth laser source, a 1×3 fiber-optic coupler, three acousto-optic modulators (AGMs), a 3×1 fiber-optic coupler, two time-delay fibers, an erbium-doped fiber amplifier (EDFA), a circulator, a photodetector, an electrical amplifier, three filters, a data acquisition card, a pulse signal generator, and a driver module. A plurality of acousto-optic modulators using the same driver are used to couple probe light with different pulse intervals and different frequency shifts and then inject the probe light into a fiber, such that a self-heterodyne detection structure with a multi-spatial resolution is implemented, which suppressed optical background noise such as coherent fading noise, phase noise introduced by a frequency drift of a light source, and pseudo-random noise (PRN).

Classes IPC  ?

  • G01D 5/353 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c.-à-d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux les rayons lumineux étant détectés par des cellules photo-électriques en modifiant les caractéristiques de transmission d'une fibre optique

92.

Method for removing chlorinated hydrocarbons in groundwater through step-by-step electrocatalytic dechlorination degradation

      
Numéro d'application 18119421
Numéro de brevet 11866352
Statut Délivré - en vigueur
Date de dépôt 2023-03-09
Date de la première publication 2023-10-05
Date d'octroi 2024-01-09
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Xu, Ke
  • Liu, Zhengqing
  • Ma, Sijia
  • Ren, Hongqiang

Abrégé

The present disclosure discloses a method for removing chlorinated hydrocarbons in groundwater through step-by-step electrocatalytic dechlorination degradation. A double-chamber electrolyzer reactor is used to carry out step-by-step electrocatalytic dechlorination degradation to remove chlorinated hydrocarbons in groundwater. The double-chamber electrolyzer reactor comprises a cathode chamber, a proton exchange membrane, an anode chamber and an intermediate processing unit, wherein the cathode chamber is separated from the anode chamber through the proton exchange membrane, and the intermediate processing unit is connected between the cathode chamber and the anode chamber through a cathode chamber water outlet, an anode chamber water inlet and pipelines. The double-chamber electrolyzer reactor adopted in the present disclosure is simple in structure and convenient to use, is capable of effectively enhancing the removal effect of electric catalysis on chlorinated hydrocarbon substances and reducing toxic and harmful substances produced by direct oxidization of chlorinated hydrocarbons, and has a good application prospect.

Classes IPC  ?

  • C02F 1/46 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques
  • C02F 1/467 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse par désinfection électrochimique
  • C02F 103/06 - Eau souterraine contaminée ou eau de lessivage
  • C02F 101/36 - Composés organiques contenant des atomes d'halogène
  • C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse

93.

MODEL TRAINING METHOD AND RELATED DEVICE

      
Numéro d'application CN2023082679
Numéro de publication 2023/185541
Statut Délivré - en vigueur
Date de dépôt 2023-03-21
Date de publication 2023-10-05
Propriétaire
  • HUAWEI TECHNOLOGIES CO., LTD. (Chine)
  • NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhan, Dechuan
  • Li, Xinchun
  • Shao, Yunfeng
  • Li, Bingshuai
  • Li, Yinchuan
  • Song, Shaoming

Abrégé

A model training method and a related device, which are applied to the technical field of artificial intelligence, and by means of which a trained model that is obtained by the joint training of a client and a server can have a sufficiently good function. The model training method comprises: when a server needs to acquire a neural network model having a data processing function, the server can issue a model to be trained to a client, wherein each neuron of a plurality of neurons in said model has a parameter and a location code; after receiving said model, the client can use local data stored therein as training data, and input same into said model, so as to process the training data by means of the parameters and location codes of the plurality of neurons in said model, thereby updating said model to obtain an updated model; and then, the client can send the updated model to the server, so that the server can perform aggregation on the basis of the updated model which is uploaded by the client, so as to obtain a trained model.

Classes IPC  ?

  • G06N 20/20 - Techniques d’ensemble en apprentissage automatique

94.

Frequency domain-based method for removing periodic noise from reconstructed light field image

      
Numéro d'application 17754874
Numéro de brevet 12165288
Statut Délivré - en vigueur
Date de dépôt 2020-09-15
Date de la première publication 2023-09-28
Date d'octroi 2024-12-10
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Cao, Xun
  • Li, Xiaowen
  • Hua, Xia

Abrégé

A method for removing periodic noise from a reconstructed light field image includes the steps of: acquiring a light field image of a sample; acquiring an optical center position map without the sample; calibrating the imaging centers of the microlenses and performing reconstruction on the light field image; transforming a reconstructed light field image to the frequency domain and generating an image frequency spectrum; preprocessing the image frequency spectrum; generating a low-pass filter; multiplying the low-pass filter with the preprocessed image frequency spectrum, and then setting the frequency spectrum value of the low-frequency component to zero; performing binarization on the reconstructed light field image frequency spectrum to obtain an image mask; removing the high-frequency periodic noise component from the original frequency spectrum of the reconstructed light field image; and transforming the filtered reconstructed light field image frequency spectrum back to the spatial domain to obtain the reconstructed light field image.

Classes IPC  ?

  • G06T 5/10 - Amélioration ou restauration d'image utilisant le filtrage dans le domaine non spatial
  • G06T 5/20 - Amélioration ou restauration d'image utilisant des opérateurs locaux
  • G06T 5/70 - DébruitageLissage
  • G06T 7/136 - DécoupageDétection de bords impliquant un seuillage
  • H04N 23/957 - Caméras ou modules de caméras à champ lumineux ou plénoptiques

95.

PROBIOTIC SYSTEM AND USE THEREOF

      
Numéro d'application 18040079
Statut En instance
Date de dépôt 2020-12-11
Date de la première publication 2023-09-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Dong, Lei
  • Han, Congwei

Abrégé

The present disclosure provides a system which enables exogenous probiotics to form a stable microenvironment in a host, can be applied by simple means such as oral administration, can achieve the effect of changing the composition of intestinal microbiota, and eventually plays a positive role in the treatment of malignant tumors.

Classes IPC  ?

  • A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
  • A61K 35/745 - Bifidobactéries
  • A61K 35/742 - Bactéries sporulées, p. ex. Bacillus coagulans, Bacillus subtilis, clostridium ou Lactobacillus sporogenes
  • A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
  • A61K 47/02 - Composés inorganiques
  • A61P 1/04 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des ulcères, des gastrites ou des œsophagites par reflux, p. ex. antiacides, antisécrétoires, protecteurs de la muqueuse
  • A61P 1/12 - Antidiarrhéiques
  • A61P 35/00 - Agents anticancéreux
  • A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
  • A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
  • A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques

96.

DIGITAL-ASSET CONFIRMATION METHOD BASED ON HASH ALGORITHM, AND DIGITAL ASSET TRACING METHOD BASED ON HASH ALGORITHM

      
Numéro d'application CN2022118786
Numéro de publication 2023/178941
Statut Délivré - en vigueur
Date de dépôt 2022-09-14
Date de publication 2023-09-28
Propriétaire
  • NANJING UNIVERSITY (Chine)
  • MATRICTIME DIGITAL TECHNOLOGY CO., LTD (Chine)
Inventeur(s)
  • Chen, Zengbing
  • Xu, Tongkai
  • Zhu, Mengya
  • Foo, Bohea
  • Yang, Ge
  • Zhao, Chengyang

Abrégé

Disclosed in the present invention a digital-asset confirmation method based on a hash algorithm, and a digital asset tracing method based on a hash algorithm. Participants during digital-asset confirmation comprise an original user, a certificate authority (CA) and a digital-asset authentication center. A confirmation process involves: the original user generating a disposable CA certificate; the digital-asset authentication center performing digital-asset authentication with the original user; the original user generating a confirmation file; the original user, the CA and the digital-asset authentication center making quantum digital signatures, etc. The tracing method comprises: generating an attachment file in real time, constructing a digital-assert unique identity at an access moment, performing traceability analysis, etc. By means of the present invention, a digital asset and the identity of an original user are confirmed, and the security of confirmation is improved to a quantum security level. In addition, according to the solution in the present invention, a digital asset in the Internet of value passes authentication, and then has a real-time unique identity, such that forward tracing can be performed by means of the real-time unique identity of the digital asset, thereby completing the tracing analysis of the digital asset.

Classes IPC  ?

  • H04L 9/32 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
  • H04L 9/08 - Répartition de clés

97.

DESIGN FOR REDUCING DARK COUNT RATE OF SNSPD BASED ON TWO-WIRE STRUCTURE

      
Numéro d'application 18011394
Statut En instance
Date de dépôt 2021-04-07
Date de la première publication 2023-09-28
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Labao
  • Yin, Rui
  • Zhang, Biao
  • Chen, Qi
  • Lv, Jiayu
  • Ge, Rui
  • Kang, Lin
  • Wu, Peiheng

Abrégé

The present invention discloses a design for reducing a dark count rate of a superconducting nanowire single photon detector (SNSPD) based on a two-wire structure, which includes: intertwining two niobium nitride nanowires that are not crossed to form an SNSPD of a two-wire structure; regulating and controlling behaviors of one nanowire by adopting the other nanowire, and regulating bias current to be close to superconducting critical current; introducing an optical signal into a photosensitive area of the detector by adopting an optical fiber; outputting two channels of signals respectively through the two nanowires to make the dark count rates of the two nanowires mutually excited; and through a voltage comparator and an exclusive-OR gate, reducing a dark count rate signal, and retaining a photon response signal. The generation of the dark count rate of the detector can be inhibited effectively by the unique performance of the SNSPD of the two-wire structure; and by improving the process latter, the coupling efficiency of the dark count rate of the SNSPD is further improved, which is expected to completely inhibit the dark count rate of the SNSPD system and greatly increase the signal-to-noise ratio of the detector.

Classes IPC  ?

98.

Flexible hydrogen sensor with ultra-high sensitivity and wide range and fabrication method therefor

      
Numéro d'application 18033072
Numéro de brevet 11774425
Statut Délivré - en vigueur
Date de dépôt 2021-05-13
Date de la première publication 2023-09-28
Date d'octroi 2023-10-03
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Li, Aidong
  • Ren, Qiang
  • Chen, Jian
  • Fang, Jiabin
  • Han, Min

Abrégé

x film (2). A traditional metal oxide type hydrogen sensor and a quantum conductance-based hydrogen sensor are combined on a flexible polymer substrate by means of an atomic layer deposition (ALD) technology and a cluster beam deposition (CBD) technology, so as to obtain a flexible hydrogen sensor with ultra-high sensitivity, a wide range and excellent selectivity and lower working temperature.

Classes IPC  ?

  • G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
  • C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
  • B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles

99.

STRUCTURED SUPERCONDUCTING-TAPE SINGLE PHOTON DETECTOR AND PREPARATION METHOD THEREFOR

      
Numéro d'application CN2022134848
Numéro de publication 2023/168996
Statut Délivré - en vigueur
Date de dépôt 2022-11-29
Date de publication 2023-09-14
Propriétaire NANJING UNIVERSITY (Chine)
Inventeur(s)
  • Zhang, Labao
  • Li, Feiyan

Abrégé

Disclosed in the present invention is a structured superconducting-tape single photon detector. In the present invention, the photon response sensitivity of a superconducting tape is improved by means of structure regulation and control, and the requirements of a conventional superconducting single photon detector regarding the width of a superconducting tape are reduced, such that high-sensitivity single-photon detection can be realized; and the structured superconducting-tape single photon detector is characterized in having a large detection area and a high speed, being simple in terms of preparation, being easily expandable to a large-scale array structure, etc. The single photon detector sequentially comprises, from bottom to top: a substrate, a structured superconducting tape, an electrode, an optical dielectric layer and an optical reflection layer. The preparation method mainly comprises: depositing a superconducting thin film on a surface of a substrate by means of magnetron sputtering; preparing a metal electrode on the superconducting thin film by means of photolithography and stripping technology; preparing on the superconducting thin film a structured superconducting tape shape by means of electron beam lithography technology and reactive ion etching technology; and respectively depositing an optical dielectric layer and a metal reflection layer on the surface of the structured superconducting tape by means of chemical vapor deposition technology and electron beam evaporation technology, which optical dielectric layer and metal reflection layer serve as optical cavities.

Classes IPC  ?

  • H01L 31/09 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet

100.

MPCVD DEVICE CAPABLE OF REALIZING EFFECTIVE DOPING

      
Numéro d'application 18116270
Statut En instance
Date de dépôt 2023-03-01
Date de la première publication 2023-09-07
Propriétaire Nanjing University (Chine)
Inventeur(s)
  • Gu, Shulin
  • Liu, Songmin
  • Zhu, Shunming
  • Ye, Jiandong
  • Tang, Kun
  • Xie, Zili
  • Zhang, Rong
  • Zheng, Youdou

Abrégé

An MPCVD device capable of realizing effective doping, comprises a reaction chamber and a gas input structure, wherein the gas input structure includes a first pipeline and a second pipeline for reaction gas, a first gas distributor, connected with the first pipeline, uniformly transports gas as a first reactant into the reaction chamber through a gas outlet of the first pipeline located near the top of the reaction chamber, the second pipeline uniformly inputs a doped reaction gas to a surface of a substrate through a second gas distributor with circular shape, a height of the gas transport ring connected with the second pipeline is substantially the same as that of a support for the substrate, and the gas transport ring can be concentrically placed at a center position inside the support, or the gas transport ring can also be concentrically placed outside the support.

Classes IPC  ?

  • C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
  • C23C 16/458 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour supporter les substrats dans la chambre de réaction
  • C23C 16/511 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des décharges à micro-ondes
  • C23C 16/27 - Le diamant uniquement
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