Abstract

Provided is a cellulose derivative in which an amount of a chelating adsorption group introduced is large and which has wettability and is capable of quickly and efficiently recovering boron.　The cellulose derivative of the present disclosure has a repeating unit represented by formula (I-1).　In formula (I-1), each Rais a hydroxy group or a group represented by formula (a). Provided that at least one of all Ra's included in the cellulose derivative is a group represented by formula (a). In formula (a), x1to X3 are the same or different and are each a group forming a complex with a hard acid according to the HSAB theory.

IPC Classes  ?

• C08B 3/14 - Preparation of cellulose esters of organic acids in which the organic acid residue contains substituents, e.g. NH2, Cl
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C08F 8/30 - Introducing nitrogen atoms or nitrogen-containing groups

Abstract

A vibratory stimulation apparatus and a vibratory stimulation method are provided. The vibratory stimulation apparatus includes at least one vibration generator configured to apply a vibration to an agonist muscle of a body of a user to thereby apply a stimulation to an antagonist muscle that forms a pair with the agonist muscle. The vibratory stimulation method includes applying a vibration to an agonist muscle of the body of a user to thereby apply the stimulation to an antagonist muscle that forms a pair with the agonist muscle.

IPC Classes  ?

• A61H 23/00 - Percussion or vibration massage, e.g. using supersonic vibrationSuction-vibration massageMassage with moving diaphragms
• A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibrationSuction-vibration massageMassage with moving diaphragms with electric or magnetic drive

Abstract

Provided is a diamond laminate that exhibits an excellent electron emission capability and can form an electrode reaction field with an excellent reducing property. The laminate of the present disclosure includes an electron excitation layer (1) having a diamond crystal structure in which some carbon atoms are substituted with nitrogen atoms, and a conductive layer (2) having a diamond crystal structure in which some carbon atoms are substituted with boron atoms. The nitrogen atom concentration in the layer (1) is preferably 5×1018 atoms/cm3 or greater, and the boron atom concentration in the layer (2) is preferably 1×1019 atoms/cm3 or greater. The thickness of the layer (1) is preferably from 1 nm to 100 μm, and the thickness of the layer (2) is preferably 1 μm or greater.

IPC Classes  ?

• C25B 11/043 - Carbon, e.g. diamond or graphene
• C25B 1/23 - Carbon monoxide or syngas

Abstract

[Problem] To provide a gas concentration device capable of continuously supplying oxygen-enriched air having a high oxygen concentration by enabling an adsorbent to demonstrate adsorption capacity with high efficiency. [Solution] An adsorption rotor including an adsorbent that preferentially adsorbs oxygen over nitrogen is divided into at least a treatment zone, a regeneration zone, and a purge zone and is configured such that the zones rotate in sequence in the stated order. Raw material air is passed through the treatment zone so that oxygen is adsorbed on the adsorbent. The air that has passed through the treatment zone is sent to a supply destination or is discharged to the atmosphere. Heated air that has passed through a regeneration heater is passed through the regeneration zone to desorb oxygen adsorbed on the adsorbent, and part of the air that has passed through the regeneration zone is taken out as oxygen-enriched air. The rest is returned to the inlet side of the regeneration heater for regeneration circulation. Air is passed through the purge zone to purge the oxygen-enriched air remaining in the adsorption rotor.

IPC Classes  ?

• C01B 13/02 - Preparation of oxygen
• B01D 53/06 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with moving adsorbents
• B01D 53/62 - Carbon oxides
• C01B 32/50 - Carbon dioxide

Abstract

The present invention provides a method of detecting a biomarker for detecting hepatocytes with bile ductular proliferation, the method including: detecting laminin γ2 single chain or a nucleic acid encoding the same as the biomarker in a specimen.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

A cell quality evaluation device comprising: a reception unit that receives a cell image; a contour extraction unit that extracts the contour of a cell included in the cell image received by the reception unit; a force information derivation unit that derives force information for the cell on the basis of the contour of the cell extracted by the contour extraction unit; a shape information derivation unit that derives shape information for the cell on the basis of the contour of the cell extracted by the contour extraction unit; and a quality evaluation unit that evaluates the quality of the cell on the basis of the shape information for the cell derived by the shape information derivation unit and the force information for the cell derived by the force information derivation unit.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
• G01N 33/483 - Physical analysis of biological material

Abstract

The present invention addresses the problem of providing a prophylactic and/or therapeutic agent for hypertensive disorders of pregnancy, which has a physical property or a molecular weight that inhibits the passage through the placental barrier, has a pharmacological activity that mimics the original physiological function of the placenta and therefore has fewer adverse side effects, is safe for a mother body and a fetus, is stable for a long period, and can exert the efficacy thereof in vivo for a long period.　The present invention is a prophylactic/therapeutic agent for pregnancy-induced hypertension, which contains aminopeptidase A (APA) as an active ingredient, the prophylactic/therapeutic agent being characterized in that the APA is bound to an immunoglobulin Fc region through a peptide linker.

IPC Classes  ?

• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 47/65 - Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
• A61P 9/12 - Antihypertensives
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 19/00 - Hybrid peptides
• C12N 9/50 - Proteinases
• C12N 15/13 - Immunoglobulins
• C12N 15/57 - Hydrolases (3) acting on peptide bonds (3.4)
• C12N 15/62 - DNA sequences coding for fusion proteins

Abstract

The objective of the present invention is to provide an amide-modified cellulose ether produced by a simple method, and an amide-modified cellulose ether using an aromatic amide.　Provided is a cellulose derivative having a repeating unit represented by formula (1), wherein the total average degree of substitution of a protecting group for a hydroxyl group, a group represented by specific formula (1-a), and a group represented by specific formula (1-b) is 1.5 or more.

IPC Classes  ?

• C08B 11/15 - Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with nitrogen-containing groups with carbamoyl groups

Abstract

The objective of the present invention is to provide an amide-modified cellulose ether produced by a simple method, and an amide-modified cellulose ether using an aromatic amide.　Provided is a cellulose derivative having a repeating unit represented by formula (1), wherein the total average degree of substitution of a protecting group for a hydroxyl group, a group represented by specific formula (1-a), and a group represented by specific formula (1-b) is 1.5 or more.

IPC Classes  ?

• C08B 13/00 - Preparation of cellulose ether-esters
• C08B 11/15 - Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with nitrogen-containing groups with carbamoyl groups

Abstract

Provided is a polynucleotide comprising at least one sequence encoding a fusion protein comprising (a) an antigen-presenting MHC molecule, which can be presented outside the membrane of a cell or an extracellular vesicle; (b) at least one T-cell stimulatory cytokine or subunit thereof, which can be presented outside the membrane of a cell or an extracellular vesicle; (c) a T-cell costimulatory molecule, which can be presented outside the membrane of a cell or an extracellular vesicle; (d) an antigen-presenting MHC molecule and at least one T-cell stimulatory cytokine or subunit thereof, which can be presented outside the membrane of a cell or an extracellular vesicle; or (e) an antigen-presenting MHC molecule, at least one T-cell stimulatory cytokine p or subunit thereof, and a T-cell costimulatory molecule, which can be presented outside the membrane of a cell or an extracellular vesicle.

IPC Classes  ?

• C07K 14/74 - Major histocompatibility complex [MHC]
• A61K 38/00 - Medicinal preparations containing peptides
• A61P 35/00 - Antineoplastic agents
• C07K 14/495 - Transforming growth factor [TGF]
• C07K 14/54 - Interleukins [IL]
• C07K 14/55 - IL-2
• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Abstract

An object of the present disclosure is to provide a method for producing a polysaccharide nanofiber-blended polysaccharide composition whose mechanical physical properties are reinforced by a polysaccharide nanofiber, and is easily carried out. A method for producing a polysaccharide nanofiber-blended polysaccharide composition is also provided which includes a step of mixing a sol containing a polysaccharide nanofiber (A), a polysaccharide (B), and a solvent (C) capable of dissolving the polysaccharide (B), and a step of drying the resultant mixture to obtain a dry mixture.

IPC Classes  ?

• C08L 1/12 - Cellulose acetate
• C08J 5/04 - Reinforcing macromolecular compounds with loose or coherent fibrous material
• C08L 3/02 - StarchDegradation products thereof, e.g. dextrin
• C08L 5/00 - Compositions of polysaccharides or of their derivatives not provided for in group or
• C08L 5/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof

Abstract

The present invention provides a reduction device that can be inexpensively and easily produced, that has a wide reaction field, that can achieve a reduction reaction even with low energy light rays of visible light, and that has a long catalyst life.　A reduction device according to the present disclosure is characterized by comprising diamond particles. The diamond particles are preferably contained in the form of a diamond particle dispersion. The diamond particles preferably include nanodiamond particles having a particle size of not more than 1 μm. The diamond particles preferably include detonation method nanodiamond particles.

IPC Classes  ?

• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
• B01J 21/18 - Carbon
• B01J 35/39 - Photocatalytic properties
• C01B 3/04 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of inorganic compounds, e.g. ammonia
• C01B 32/40 - Carbon monoxide

Abstract

Provided is a semiconductor catalyst that exhibits an effect of promoting a reduction reaction by visible light irradiation and has excellent durability.　A semiconductor catalyst according to the present disclosure comprises a thin film that contains nitrogen-containing diamond particles in the surface direction and the height direction.　The semiconductor catalyst can be manufactured, for example, by performing step 1, and then performing step 2 at least once. Step 1: a step for immobilizing, on a substrate having a positive or negative charge, nitrogen-containing diamond particles which have a positive or negative charge and have a charge opposite to the charge of the substrate, Step 2: a step for laminating, on the immobilized nitrogen-containing diamond particles, nitrogen-containing diamond particles which have a positive or negative charge and have a charge opposite to the charge of the immobilized nitrogen-containing diamond particles.

IPC Classes  ?

• B01J 21/18 - Carbon
• B01J 27/24 - Nitrogen compounds
• B01J 35/39 - Photocatalytic properties
• B01J 35/54 - Bars or plates
• B01J 37/02 - Impregnation, coating or precipitation
• C01B 3/04 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of inorganic compounds, e.g. ammonia
• C01B 32/26 - Preparation
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 1/55 - Photoelectrolysis
• C25B 9/00 - Cells or assemblies of cellsConstructional parts of cellsAssemblies of constructional parts, e.g. electrode-diaphragm assembliesProcess-related cell features
• C25B 9/50 - Cells or assemblies of cells comprising photoelectrodesAssemblies of constructional parts thereof
• C25B 11/043 - Carbon, e.g. diamond or graphene
• C25B 11/049 - Photocatalysts
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/083 - Diamond
• C25B 11/087 - Photocatalytic compound

Abstract

The present invention accurately infers the presence or absence of a disease. An information processing device (1A) comprises: an image acquisition unit (11) that acquires an image that has captured therein a target site of a subject to which a radiopharmaceutical has been administered; a variation index calculation unit (51) that calculates, on the basis of the image, a variation index (23) indicating the degree of variation in radiation dose at the target site, the radiation dose being emitted from the radiopharmaceutical accumulated in the target site of the subject; and an inference unit (12) that infers a disease at the target site of the subject on the basis of the calculated variation index (23).

IPC Classes  ?

• G01T 1/161 - Applications in the field of nuclear medicine, e.g. in vivo counting
• G06T 7/00 - Image analysis

Abstract

A fuel cell system includes a fuel cell, an electric power recovery device, and a control device that controls the fuel cell and the electric power recovery device. In a state where supplying of the liquid fuel to the fuel cell is stopped, the control device charges post-stop electric power generated by the fuel cell using the liquid fuel that has been already supplied, thereby recovering the post-stop electric power into the electric power recovery device, and thereafter stopping an electrode reaction in an electrode structure of the fuel cell.

IPC Classes  ?

• H01M 8/04858 - Electric variables
• H01M 8/04223 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids during start-up or shut-downDepolarisation or activation, e.g. purgingMeans for short-circuiting defective fuel cells
• H01M 8/04228 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids during start-up or shut-downDepolarisation or activation, e.g. purgingMeans for short-circuiting defective fuel cells during shut-down
• H01M 8/04303 - Processes for controlling fuel cells or fuel cell systems applied during specific periods applied during shut-down
• H01M 8/04537 - Electric variables
• H01M 8/04746 - PressureFlow
• H01M 8/04955 - Shut-off or shut-down of fuel cells
• H01M 16/00 - Structural combinations of different types of electrochemical generators

Abstract

[Problem] The purpose of the present invention is to provide a nickel substrate for obtaining a large diameter diamond substrate, and to provide a method for manufacturing a diamond substrate using the nickel substrate. [Solution] This nickel substrate is to be used for the heteroepitaxial growth of a diamond layer, and is characterized in that the nickel substrate is formed of single crystals, and has a (111) crystal surface on the surface thereof.

IPC Classes  ?

• C30B 29/04 - Diamond
• C23C 16/02 - Pretreatment of the material to be coated
• C23C 16/27 - Diamond only
• H01L 21/205 - Deposition of semiconductor materials on a substrate, e.g. epitaxial growth using reduction or decomposition of a gaseous compound yielding a solid condensate, i.e. chemical deposition

Abstract

The present invention provides a composition for regulating carbohydrate metabolism, the composition containing, as an active ingredient, an agent for controlling the amount of D-amino acid in the living body of a subject. Moreover, the present invention provides a method for assessing carbohydrate metabolism conditions of a subject by monitoring the amount of D-amino acid in the living body of the subject.

IPC Classes  ?

• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

A kneading state detection device includes an acquisition unit that, when an extrusion molding machine that kneads a raw material or kneads a raw material and an additive is in operation, acquires an output of an AE sensor installed on a housing of the extrusion molding machine, and a determination unit that determines a kneading state of the raw material, based on a comparison between a change in intensity of the output of the AE sensor acquired by the acquisition unit and a threshold.

IPC Classes  ?

• B29B 7/72 - Measuring, controlling or regulating
• B29B 7/48 - MixingKneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
• G01N 29/14 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object using acoustic emission techniques
• G01N 29/44 - Processing the detected response signal
• G01N 29/46 - Processing the detected response signal by spectral analysis, e.g. Fourier analysis

Abstract

There is provided a cellulose derivative that has a high amount of a chelate adsorption group introduced, has high hydrophilicity, and is capable of efficiently recovering boron. There is provided a cellulose derivative that has a high amount of a chelate adsorption group introduced, has high hydrophilicity, and is capable of efficiently recovering boron. The cellulose derivative of the present disclosure has a repeating unit represented by the following formula (1-1). In the following formula (I-1), Ra is the same as or different from each other, and is a hydroxyl group or a group represented by the following formula (a). In the following formula (a), R1 represents a hydrogen atom or a methyl group. R2 represents a hydrogen atom or a hydrocarbon group optionally having a hydroxyl group. R3 represents a hydrogen atom or a hydrocarbon group. Note that at least one of all R3 contained in the cellulose derivative is the group represented by the following formula (a). There is provided a cellulose derivative that has a high amount of a chelate adsorption group introduced, has high hydrophilicity, and is capable of efficiently recovering boron. The cellulose derivative of the present disclosure has a repeating unit represented by the following formula (1-1). In the following formula (I-1), Ra is the same as or different from each other, and is a hydroxyl group or a group represented by the following formula (a). In the following formula (a), R1 represents a hydrogen atom or a methyl group. R2 represents a hydrogen atom or a hydrocarbon group optionally having a hydroxyl group. R3 represents a hydrogen atom or a hydrocarbon group. Note that at least one of all R3 contained in the cellulose derivative is the group represented by the following formula (a).

IPC Classes  ?

• B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties

Abstract

Provided is a technology that enables liquid plasma treatment of a substrate surface at low power.　A plasma treatment device (10) comprises: a chamber (20) that stores a liquid Lq; a substrate holder (50) that holds a substrate Wf while the substrate is disposed in the liquid; a gas chamber (60) which accommodates a gas Ga, which has an opening (64) in an area opposing the substrate, and in which at least the opening is disposed inside the liquid of the chamber and is spaced apart from the substrate; a microwave generation device (80) that generates microwaves; a waveguide (82) that has a prescribed area (84) disposed inside the gas chamber and that transmits, to the prescribed area, the microwaves generated by the microwave generation device; and an antenna (90) that is disposed in the prescribed area of the waveguide and that induces plasma by projecting the microwaves into the gas chamber.

IPC Classes  ?

• H05H 1/30 - Plasma torches using applied electromagnetic fields, e.g. high-frequency or microwave energy
• H01L 21/304 - Mechanical treatment, e.g. grinding, polishing, cutting
• H05H 1/24 - Generating plasma

Abstract

A track generation device generates a track of a fluid discharge unit that discharges a fluid for applying the fluid to a surface of an object along a target application track. The track generation device includes a storage unit and a track generation unit. The storage unit stores a time-series model indicating a relationship between the track of the fluid discharge unit and an application track of the fluid in consideration of behavior of the fluid due to a viscosity, and the relationship is learned based on an actual track of the fluid discharge unit and an actual application track of the fluid. The track generation unit is configured to generate the track of the fluid discharge unit corresponding to the target application track using the time-series model upon reception of the target application track.

IPC Classes  ?

• B05C 11/10 - Storage, supply or control of liquid or other fluent materialRecovery of excess liquid or other fluent material
• B05C 5/02 - Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work from an outlet device in contact, or almost in contact, with the work

Abstract

An acetabulum-reinforcing implant (1) according to one embodiment comprises: a dome section (2) which includes a vertical frame and a horizontal frame which intersect one another and curve along a spherical surface which corresponds to the acetabulum (92); a flat pallet section (3) which is screwed to the ilium (91) and is folded upward from the vertical frame; and a hook section (4) which engages the obturator foramen and extends downward from the vertical frame. When the acetabulum-reinforcing implant (1) is attached to the pelvis (9), the hook section (4) is inclined relative to the vertical frame toward the front of the pelvis (9) and twists increasingly more toward the front of the pelvis (9) relative to the vertical frame in the medial direction of the pelvis (9), in a manner such that the pallet section (3) intersects the mediolateral direction of the pelvis (9) and a vertical axis (1A), which is a projection of the center line (21a) of the vertical frame (21) onto a plane extending along the pallet section (3), is parallel to the pelvic plane.

IPC Classes  ?

• A61F 2/34 - Acetabular cups

Abstract

The present invention provides a novel substance that suitably functions as an Met agonist. The present invention provides an artificial protein that includes an antibody Fc region, where an amino acid represented by SEQ ID NO: 1 is inserted into the Fc region (in SEQ ID NO: 1, X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, and X11each independently represents an amino acid, and n1 and n2 are each independently an integer from 0 to 6).　(X1n1n1YX3X4FYYNYX 5X6X7WX8X9X10X11(X2n2n2 (SEQ ID NO: 1)

IPC Classes  ?

• C07K 19/00 - Hybrid peptides
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A61P 3/06 - Antihyperlipidemics
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61P 9/14 - VasoprotectivesAntihaemorrhoidalsDrugs for varicose therapyCapillary stabilisers
• A61P 11/00 - Drugs for disorders of the respiratory system
• A61P 11/06 - Antiasthmatics
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61P 17/00 - Drugs for dermatological disorders
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies

Abstract

This method for producing a fiber-reinforced composite material includes: a fiber dispersion process of providing a fiber-dispersed resin by kneading a resin 10a with fibers 10b to disperse the fibers 10b in the resin 10a; and a molecular weight reduction process in which, while transporting the fiber-dispersed resin along an outer peripheral surface of a screw body 37 provided with a passage 88 inside, the fiber-dispersed resin passes from an inlet 91 of the passage 88 to an outlet 92 of the passage 88 and a shear force is applied to the fiber-dispersed resin by restricting the transport of the fiber-dispersed resin with a barrier unit 82 disposed between the inlet 91 and the outlet 92 of the passage 88 on the outer peripheral surface.

IPC Classes  ?

• B29B 7/90 - Fillers or reinforcements
• B29B 7/42 - MixingKneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with single shaft with screw or helix
• B29C 70/06 - Fibrous reinforcements only

Abstract

A production device for melt-blown non-woven fabric, with which a high molecular weight polymer can be reduced in molecular weight by applying a shear force to the high molecular weight polymer without adding an additive such as a peroxide that promotes thermal decomposition reaction, and a low molecular weight polymer can be efficiently produced. The low molecular weight polymer and the melt-blown non-woven fabric are produced using a continuous high shearing device that applies a shear force to the high molecular weight polymer serving as a raw material by rotation of a screw body 37 to reduce the molecular weight of the high molecular weight polymer so as to obtain a low molecular weight polymer, and cools the low molecular weight polymer by passing the low molecular weight polymer through a passage 88 arranged in the axial direction inside the screw body 37.

IPC Classes  ?

• D04H 1/56 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving in association with fibre formation, e.g. immediately following extrusion of staple fibres
• B29C 48/88 - Thermal treatment of the stream of extruded material, e.g. cooling
• B29C 48/86 - Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling at the nozzle zone
• B29C 48/30 - Extrusion nozzles or dies
• B29C 48/05 - Filamentary, e.g. strands
• B29C 48/285 - Feeding the extrusion material to the extruder
• B29B 7/48 - MixingKneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
• B29B 7/72 - Measuring, controlling or regulating
• B29B 7/82 - Heating or cooling
• D04H 1/4291 - Olefin series

Abstract

The present invention relates to a BODIPY compound, and a temperature-sensitive fluorescent sensor of cell organelles comprising same. A BODIPY compound according to one aspect can quickly detect minute temperature changes with high sensitivity and accurately target various cell organelles, and has no cytotoxicity. That is, the BODIPY compound according to one aspect can visualize the temperature for each cell organelle and is expected to be useful as a temperature-sensitive fluorescent sensor of cell organelles.

IPC Classes  ?

• C07F 5/02 - Boron compounds
• G01K 11/20 - Measuring temperature based on physical or chemical changes not covered by group , , , or using thermoluminescent materials
• G01K 11/16 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance of organic materials

Abstract

Provided are a novel complex having the effect of efficiently adsorbing and collecting arsenic(V) dissolved in water, and a novel arsenic adsorbent. The complex has a structure in which metal particles including zero-valent and/or trivalent iron are supported on a microfibrous cellulose surface. The metal particles of the complex contain at least one type of metal oxide, hydroxide or oxyhydroxide selected from zirconium and titanium, together with zero-valent and/or trivalent iron. The molar ratio [iron/(zirconium + titanium)] of iron (elementary iron equivalent) and the metal oxide, hydroxide and oxyhydroxide (elementary metal equivalent; total amount when containing two or more compounds) is preferably 1 to 100. The arsenic adsorbent contains the complex.

IPC Classes  ?

• B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption

Abstract

Provided are: a novel complex capable of efficiently adsorbing and collecting arsenic (V) dissolved in water; and a novel arsenic adsorbent.　This complex contains iron (III)-containing particles supported on microfibrous cellulose. At least a portion of the iron (III)-containing particles has an aspect ratio of 2 or more.　The iron (III)-containing particles preferably contain at least one iron compound selected from iron oxides, iron hydroxides, and iron oxyhydroxides.　This arsenic adsorbent contains the complex.

IPC Classes  ?

• B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption

Abstract

The present invention provides a novel complex having the effect of efficiently adsorbing and collecting arsenic(V) dissolved in water, and a novel arsenic adsorbent.　A complex according to the present disclosure has a structure in which metal particles including zero-valent and/or trivalent iron are supported on a microfibrous cellulose surface.　The metal particles of the complex contain at least one type of metal oxide, hydroxide, or oxyhydroxide selected from zirconium and titanium, together with zero-valent and/or trivalent iron. The molar ratio [iron/(zirconium + titanium)] of the iron (elementary iron equivalent) and the metal oxide, hydroxide, or oxyhydroxide (elementary metal equivalent; total amount when containing two or more compounds) is preferably 1-100.　An arsenic adsorbent according to the present disclosure contains the complex.

IPC Classes  ?

• B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption

Abstract

Provided are [0] extracellular vesicles that present at least one cytokine extramembranously; [1] extracellular vesicles that present at least one target factor extramembranously; or [2] extracellular vesicles that present at least one target factor and at least one cytokine extramembranously.

IPC Classes  ?

• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells
• A61P 7/06 - Antianaemics
• A61P 35/00 - Antineoplastic agents
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• C07K 14/52 - CytokinesLymphokinesInterferons
• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C07K 19/00 - Hybrid peptides
• C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
• C12N 5/074 - Adult stem cells
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/19 - InterferonsLymphokinesCytokines
• C12N 15/62 - DNA sequences coding for fusion proteins
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Abstract

Provided are a novel complex capable of efficiently adsorbing and collecting arsenic(V) dissolved in water, and a novel arsenic adsorbent. This complex contains iron(III)-containing particles supported on microfibrous cellulose, and at least a portion of the iron(III)-containing particles has an aspect ratio of two or more. The iron(III)-containing particles preferably contain at least one iron compound selected from iron oxides, iron hydroxides, and iron oxyhydroxides. The arsenic adsorbent contains the complex.

IPC Classes  ?

• B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption

Abstract

A fuel flow groove formed in a fuel electrode current collector of a fuel electrode of a fuel cell includes a plurality of flow groove portions disposed in parallel, and a plurality of return groove portions connecting an end portion of one side edge portion or an end portion of the other side edge portion of the flow groove portions of two adjacent groups. Each of the return groove portions has an inner wall surface portion facing the end portion of the flow groove portions in the return groove portions. The inner wall surface portion has a curved surface shape in which a distance facing each other from the inner wall surface portion to the end portion of the flow groove portions, gradually decreases toward both end portions of the inner side wall surface portion in a direction orthogonal to an extending direction of the flow groove portions.

IPC Classes  ?

• H01M 8/026 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant characterised by grooves, e.g. their pitch or depth
• H01M 8/04082 - Arrangements for control of reactant parameters, e.g. pressure or concentration
• H01M 8/0265 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant the reactant or coolant channels having varying cross sections

Abstract

The present disclosure provides an adsorbent which is produced using a low environmental load material as a raw material and adsorbs selenious acid selectively and efficiently. A selenious acid adsorbent according to the present disclosure includes a cellulose derivative (I) having a repeating unit represented by Formula (I). In Formula (I), each Ra represents a hydrogen atom, a group represented by Formula (a-1), or a group represented by Formula (a-2), and at least one of all the Ras included in the cellulose derivative is a group represented by Formula (a-1) or a group represented by Formula (a-2): The present disclosure provides an adsorbent which is produced using a low environmental load material as a raw material and adsorbs selenious acid selectively and efficiently. A selenious acid adsorbent according to the present disclosure includes a cellulose derivative (I) having a repeating unit represented by Formula (I). In Formula (I), each Ra represents a hydrogen atom, a group represented by Formula (a-1), or a group represented by Formula (a-2), and at least one of all the Ras included in the cellulose derivative is a group represented by Formula (a-1) or a group represented by Formula (a-2):

IPC Classes  ?

• B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• B01J 20/30 - Processes for preparing, regenerating or reactivating

Abstract

Provided is a method for simply and efficiently recovering an ionic liquid from a liquid mixture including the ionic liquid and an organic acid.　This method for recovering an ionic liquid from a liquid mixture including the ionic liquid and an organic acid is characterized in that the ionic liquid is water soluble, water and an organic solvent (excluding organic acids) are blended into the liquid mixture, and the organic acid is separated by extraction.

IPC Classes  ?

• C07D 233/58 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
• C08B 3/06 - Cellulose acetate
• C08B 3/22 - Post-esterification treatments, including purification

Abstract

The present invention provides a method for easily and efficiently recovering an ionic liquid from a liquid mixture that contains the ionic liquid and an organic acid.　This method for recovering an ionic liquid is characterized by subjecting a liquid mixture (A) that contains an ionic liquid, an organic acid and a solvent (excluding an organic acid) to distillation.

IPC Classes  ?

• C07D 233/58 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
• C08B 3/06 - Cellulose acetate
• C08B 3/22 - Post-esterification treatments, including purification

Abstract

Provided is a method for simply and efficiently recovering an ionic liquid from a liquid mixture including the ionic liquid and an organic acid.　This method for recovering an ionic liquid from a liquid mixture including the ionic liquid and an organic acid is characterized in that a solvent (excluding organic acids) is mixed into the liquid mixture and distillation is performed. The solvent is preferably a polar solvent. The HSP value (MPA)0.5 at 25°C of the polar solvent is preferably 15 or higher.

IPC Classes  ?

• C07D 233/58 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
• C08B 3/06 - Cellulose acetate
• C08B 3/22 - Post-esterification treatments, including purification

Abstract

Provided is a method for simply and efficiently recovering an ionic liquid from a liquid mixture including the ionic liquid and an organic acid.　This method for recovering an ionic liquid from a liquid mixture including the ionic liquid and an organic acid is characterized in that the ionic liquid is water-soluble, at least one of water and an organic solvent (excluding organic acids) is blended into the liquid mixture, and the organic acid is separated by extraction.

IPC Classes  ?

• C07D 233/58 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
• C08B 3/06 - Cellulose acetate
• C08B 3/22 - Post-esterification treatments, including purification

Abstract

The present disclosure provides a cellulose derivative which has excellent storage stability and can selectively adsorb a valuable metal and a toxic metal. The cellulose derivative of the present disclosure has a repeating unit represented by Formula (I) below. In Formula (I) below. Ras are identical or different and are a hydrogen atom or a group represented by Formula (a) below. In Formula (a) below, ring Z represents a heterocycle containing a nitrogen atom as a heteroatom, and R1 represents a single bond or an alkylene group having from 1 to 10 carbons. Four R2s are identical or different, and each represent an alkyl group having from 1 to 10 carbons. At least one of all the Ras included in the cellulose derivative is a group represented by Formula (a) below. The present disclosure provides a cellulose derivative which has excellent storage stability and can selectively adsorb a valuable metal and a toxic metal. The cellulose derivative of the present disclosure has a repeating unit represented by Formula (I) below. In Formula (I) below. Ras are identical or different and are a hydrogen atom or a group represented by Formula (a) below. In Formula (a) below, ring Z represents a heterocycle containing a nitrogen atom as a heteroatom, and R1 represents a single bond or an alkylene group having from 1 to 10 carbons. Four R2s are identical or different, and each represent an alkyl group having from 1 to 10 carbons. At least one of all the Ras included in the cellulose derivative is a group represented by Formula (a) below. The present disclosure provides a cellulose derivative which has excellent storage stability and can selectively adsorb a valuable metal and a toxic metal. The cellulose derivative of the present disclosure has a repeating unit represented by Formula (I) below. In Formula (I) below. Ras are identical or different and are a hydrogen atom or a group represented by Formula (a) below. In Formula (a) below, ring Z represents a heterocycle containing a nitrogen atom as a heteroatom, and R1 represents a single bond or an alkylene group having from 1 to 10 carbons. Four R2s are identical or different, and each represent an alkyl group having from 1 to 10 carbons. At least one of all the Ras included in the cellulose derivative is a group represented by Formula (a) below.

IPC Classes  ?

• B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption

Abstract

A fuel cell includes a discharge structure that discharges water generated in a cathode electrode in association with an electrode reaction in the MEA to the outside. The discharge structure includes a discharge path through which air that is an oxidant flows, a passage that communicably connects an oxidant supply flow path and the discharge path and that moves water generated in the cathode electrode to the discharge path, and a discharge portion that discharges the generated water moved to the discharge path to the outside.

IPC Classes  ?

• H01M 8/04291 - Arrangements for managing water in solid electrolyte fuel cell systems
• H01M 8/0258 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant
• H01M 8/04186 - Arrangements for control of reactant parameters, e.g. pressure or concentration of liquid-charged or electrolyte-charged reactants
• H01M 8/1009 - Fuel cells with solid electrolytes with one of the reactants being liquid, solid or liquid-charged

Abstract

[Problem] To provide a malaria vaccine which has an excellent preventative effect against infection and excellent effect of inhibiting malaria transmission, as compared to conventional malaria vaccines. [Solution] It was found that using, as a prime, a recombinant vaccinia virus which includes a gene that codes a CSP amino acid sequence and a gene that codes an s25 amino acid sequence, and using, as a boost, a recombinant adeno-associated virus which includes a gene that codes a CSP amino acid sequence and a gene that codes an s25 amino acid sequence results in a malaria vaccine which has an excellent preventative effect against infection and excellent effect of inhibiting malaria transmission.

IPC Classes  ?

• A61K 39/015 - Hemosporidia antigens, e.g. Plasmodium antigens
• A61K 39/23 - Parvoviridae, e.g. feline panleukopenia virus
• A61K 39/285 - Vaccinia virus or variola virus
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 33/06 - Antimalarials
• A61P 37/04 - Immunostimulants
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• C12N 7/01 - Viruses, e.g. bacteriophages, modified by introduction of foreign genetic material
• C12N 15/30 - Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria
• C12N 15/863 - Poxviral vectors, e.g. vaccinia virus
• C12N 15/864 - Parvoviral vectors
• A61K 35/76 - VirusesSubviral particlesBacteriophages

Abstract

A method for manufacturing diamond substrate of using source gas containing hydrocarbon gas and hydrogen gas to form diamond crystal on an underlying substrate by CVD method, to form a diamond crystal layer having nitrogen-vacancy centers in at least part of the diamond crystal, nitrogen or nitride gas is mixed in the source gas, wherein the source gas is: 0.005 volume % or more and 6.000 volume % or less of the hydrocarbon gas; 93.500 volume % or more and less than 99.995 volume % of the hydrogen gas; and 5.0×10−5 volume % or more and 5.0×10−1 volume % or less of the nitrogen gas or the nitride gas, and the diamond crystal layer having the nitrogen-vacancy centers is formed. A method for manufacturing a diamond substrate to form an underlying substrate, a diamond crystal having a dense nitrogen-vacancy centers (NVCs) with an orientation of NV axis by performing the CVD.

IPC Classes  ?

• C30B 29/04 - Diamond
• C23C 16/02 - Pretreatment of the material to be coated
• C23C 16/27 - Diamond only
• C30B 25/18 - Epitaxial-layer growth characterised by the substrate
• H01F 1/40 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties of inorganic materials of magnetic semiconductor materials, e.g. CdCr2S4
• C30B 25/20 - Epitaxial-layer growth characterised by the substrate the substrate being of the same materials as the epitaxial layer

Abstract

To provide extracellular vesicles capable of satisfactorily activating, etc., antigen-specific T cells. Provided are said antigen-presenting extracellular vesicles that present an antigen-presenting MHC molecule and a T-cell-stimulating cytokine extramembranously.

IPC Classes  ?

• C12N 15/62 - DNA sequences coding for fusion proteins
• C07K 14/74 - Major histocompatibility complex [MHC]
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C07K 14/55 - IL-2
• C07K 14/54 - Interleukins [IL]
• C07K 14/52 - CytokinesLymphokinesInterferons
• C07K 14/495 - Transforming growth factor [TGF]
• A61P 37/08 - Antiallergic agents
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention provides a novel semiconductor device for high breakdown voltage having no drift layer. The semiconductor device includes a first semiconductor layer of a first conductivity type which is either a p-type or an n-type conductivity type, a source portion arranged so as to be in contact with the first semiconductor layer and configured as a semiconductor portion of a second conductivity type different from the first conductivity type, a source electrode arranged in ohmic contact with the source portion, a gate electrode arranged on at least one selected from surfaces of the first semiconductor layer via a gate insulating film interposed therebetween and capable of forming by an applied electric field, an inversion layer in a region of the first semiconductor layer near the surface of the first semiconductor layer contacting the gate insulating film, a second semiconductor layer of the first conductivity type arranged so as to be in contact with the inversion layer, and a drain electrode separated from the inversion layer and arranged in Schottky contact with the second semiconductor layer.

IPC Classes  ?

• H01L 29/78 - Field-effect transistors with field effect produced by an insulated gate
• H01L 29/16 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only elements of Group IV of the Periodic System in uncombined form
• H01L 29/41 - Electrodes characterised by their shape, relative sizes or dispositions

Abstract

The present invention provides a diamond laminate which has excellent electron emission ability and is capable of forming an electrode reaction field that has excellent reductiveness.　A laminate according to the present disclosure comprises: an electron excitation layer (1) that has a diamond crystal structure in which some carbon atoms are substituted by nitrogen atoms; and a conductive layer (2) that has a diamond crystal structure in which some carbon atoms are substituted by boron atoms.　It is preferable that the nitrogen atom concentration in the layer (1) is 5 × 1018atoms/cm3or more; and it is preferable that the boron atom concentration in the layer (2) is 1 × 1019atoms/cm3 or more.　It is preferable that the thickness of the layer (1) is 1 nm to 100 µm; and it is preferable that the thickness of the layer (2) is 1 µm or more.

IPC Classes  ?

• C25B 11/083 - Diamond
• B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
• C01B 32/25 - Diamond
• C25B 1/23 - Carbon monoxide or syngas
• C25B 1/55 - Photoelectrolysis
• C25B 9/00 - Cells or assemblies of cellsConstructional parts of cellsAssemblies of constructional parts, e.g. electrode-diaphragm assembliesProcess-related cell features
• C25B 11/065 - Carbon
• C25B 11/087 - Photocatalytic compound

Abstract

A magnetostrictive vibrational power generator that obtains power using the magnetostriction effect produced in a magnetostriction element 13, and is obtained by comprising: a beam member 10 that has one end configured as a free end and the other end configured as a fixed end, and is integrally provided with a rod-shaped magnetostriction element 13 and a frame 12 to which the magnetostriction element 13 is mounted; magnets 14a, b that impart a magnetic bias to the magnetostriction element 13; a coil 15 that is wound around the magnetostriction element 13 so as to be penetrated by the magnetic flux produced by the magnetostriction element 13 to which the magnetic bias has been applied; and a rotational tab member 20 that is positioned near the beam member 10, and is obtained by arranging, at prescribed intervals on an outer circumferential section of a rotational body 21, a plurality of tab sections 23 which pull the free end of the frame 12 such that the magnetostriction element 13 sags.

IPC Classes  ?

• H02N 2/18 - Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing electrical output from mechanical input, e.g. generators
• H10N 35/00 - Magnetostrictive devices

Abstract

The invention provides a polynucleotide including at least one of (a) a sequence encoding a fusion protein including an antigen-presenting MHC molecule capable of being presented extramembranously of an extracellular vesicle; (b) a sequence encoding a fusion protein including a T cell stimulating cytokine or a subunit thereof capable of being presented extramembranously of an extracellular vesicle; (c) a sequence encoding a fusion protein including a T cell co-stimulatory molecule capable of being presented extramembranously of an extracellular vesicle; (d) a sequence encoding a fusion protein including an antigen-presenting MHC molecule and a T cell stimulating cytokine or a subunit thereof capable of being presented extramembranously of an extracellular vesicle; and (e) a sequence encoding a fusion protein including an antigen-presenting MHC molecule, a T cell stimulating cytokine or a subunit thereof, and a T cell co-stimulatory molecule capable of being presented extramembranously of an extracellular vesicle.

IPC Classes  ?

• C07K 14/55 - IL-2
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C07K 14/74 - Major histocompatibility complex [MHC]
• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C07K 14/485 - Epidermal growth factor [EGF], i.e. urogastrone
• C07K 14/54 - Interleukins [IL]
• C07K 14/495 - Transforming growth factor [TGF]
• A61K 35/15 - Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cellsMyeloid precursor cellsAntigen-presenting cells, e.g. dendritic cells

Abstract

Provided is a water-insoluble crosslinked structure having an excellent metal-scavenging effect.　In this crosslinked structure, one linear polymer having a plurality of pendant groups represented by formula (a) and another linear polymer having a plurality of pendant groups represented by formula (a) are crosslinked as a result of some of the pendant groups in the one linear polymer and some of the pendant groups in the other linear polymer bonding to each other via a crosslinking agent. In the formula, the ring Z denotes a heterocyclic ring that contains a nitrogen atom as a heteroatom, and R1denotes a single bond or an alkylene group having 1-10 carbon atoms. Q+ denotes a counter cation.

IPC Classes  ?

• C08G 81/00 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
• B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
• B01J 20/26 - Synthetic macromolecular compounds
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C08B 3/14 - Preparation of cellulose esters of organic acids in which the organic acid residue contains substituents, e.g. NH2, Cl
• C08F 8/30 - Introducing nitrogen atoms or nitrogen-containing groups
• C08F 8/34 - Introducing sulfur atoms or sulfur-containing groups
• C08F 16/06 - Polyvinyl alcohol
• C08G 59/02 - Polycondensates containing more than one epoxy group per molecule
• C08G 79/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon

Abstract

Provided is a water-insoluble crosslinked structure having an exceptional metal scavenging effect.　In the crosslinked structure according to the present disclosure, one linear polymer having a plurality of pendant groups represented by formula (a) and another linear polymer having a plurality of pendant groups represented by formula (a) are crosslinked by binding some of the pendant groups of the one linear polymer and some of the pendant groups of the other linear polymer to one another using a cross-linking agent. In the formula, ring Z represents a heterocycle including a nitrogen atom as a heteroatom, and R1represents a single bond or a C1-10 alkylene group. Q+ represents a counter cation.

IPC Classes  ?

• C08G 81/00 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
• B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
• B01J 20/26 - Synthetic macromolecular compounds
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C08B 3/14 - Preparation of cellulose esters of organic acids in which the organic acid residue contains substituents, e.g. NH2, Cl
• C08F 8/14 - Esterification
• C08F 8/30 - Introducing nitrogen atoms or nitrogen-containing groups
• C08F 8/34 - Introducing sulfur atoms or sulfur-containing groups
• C08F 16/06 - Polyvinyl alcohol
• C08G 59/02 - Polycondensates containing more than one epoxy group per molecule
• C08G 79/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon

Abstract

This method for producing a fiber-reinforced composite material comprises: a fiber dispersion step for providing a fiber-dispersed resin by kneading a resin 10a with a fiber 10b to disperse the fiber 10b in the resin 10a; and a molecular weight reduction step in which, while transporting the fiber-dispersed resin along an outer peripheral surface of a screw body 37 provided with a passage 88 in the interior, the fiber-dispersed resin is passed from an entrance 91 to the passage 88 to an outlet 92 of the passage 88 and in combination therewith a shear force is applied to the fiber-dispersed resin by restricting the transport of the fiber-dispersed resin with a barrier element 82 disposed between the inlet 91 of the passage 88 at the outer peripheral surface and the outlet 92.

IPC Classes  ?

• B29B 7/38 - MixingKneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary
• B29B 7/90 - Fillers or reinforcements
• B29C 48/375 - Plasticisers, homogenisers or feeders comprising two or more stages
• B29C 48/51 - Screws with internal flow passages, e.g. for molten material
• B29C 48/74 - Bypassing means, i.e. part of the molten material being diverted into downstream stages of the extruder
• B29K 105/12 - Condition, form or state of moulded material containing reinforcements, fillers or inserts of short lengths, e.g. chopped filaments, staple fibres or bristles

Abstract

Provided is a polynucleotide from which a cell or extracellular vesicle capable of satisfactorily activating antigen-specific T cells can be produced.　Provided is a polynucleotide containing at least one sequence selected from the group consisting of: (a) a sequence encoding a fusion protein (A) including an antigen-presenting MHC molecule and capable of presenting the antigen-presenting MHC molecule on the outside of the membrane of a cell or extracellular vesicle; (b) a sequence encoding a fusion protein (B) including at least one T cell stimulating cytokine or a subunit thereof and capable of presenting the T cell stimulating cytokine on the outside of the membrane of a cell or extracellular vesicle; (c) a sequence encoding a fusion protein (C) including a T cell co-stimulatory molecule and capable of presenting the T cell co-stimulatory molecule on the outside of the membrane of a cell or extracellular vesicle; (d) a sequence encoding a fusion protein (D) including an antigen-presenting MHC molecule and at least one T cell stimulating cytokine or a subunit thereof and capable of presenting the antigen and the T cell stimulating cytokine on the outside of the membrane of a cell or extracellular vesicle; and (e) a sequence encoding a fusion protein (E) including an antigen-presenting MHC molecule, at least one T cell stimulating cytokine or a subunit thereof, and a T cell co-stimulatory molecule and capable of presenting the antigen, the T cell stimulating cytokine, and the T cell co-stimulatory molecule on the outside of the membrane of a cell or extracellular vesicle.

IPC Classes  ?

• C12N 15/62 - DNA sequences coding for fusion proteins
• A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
• A61K 36/06 - Fungi, e.g. yeasts
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61P 35/00 - Antineoplastic agents
• A61P 37/02 - Immunomodulators
• A61P 37/08 - Antiallergic agents
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• C07K 14/495 - Transforming growth factor [TGF]
• C07K 14/54 - Interleukins [IL]
• C07K 14/55 - IL-2
• C07K 14/74 - Major histocompatibility complex [MHC]
• C07K 19/00 - Hybrid peptides
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/19 - InterferonsLymphokinesCytokines
• C12N 15/24 - Interleukins
• C12N 15/26 - Interleukin-2
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

A polyrotaxane of high heat resistance contains a linear molecule, a cyclic molecule enclosing the linear molecule such that the cyclic molecule is skewered with the linear molecule, and 5 blocking groups disposed at both ends of the linear molecule. The cyclic molecule contains an aromatic ring having, on a side chain, a phenolic hydroxyl group. The polyrotaxane can be produced by dissolving, in a methanol-containing solvent, a linear molecule and a cyclic 10 molecule containing an aromatic ring having, on a side chain, a phenolic hydroxyl group, to yield a pseudo polyrotaxane in which the cyclic molecule encloses the linear molecule such that the cyclic molecule is skewered with the linear molecule; and dissolving the pseudo polyrotaxane and a blocking group 15 material in a solvent, to dispose blocking groups at both ends of the linear molecule.

IPC Classes  ?

• C08G 65/26 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds

Abstract

Provided is a cellulose derivative which has a high amount of chelate adsorption groups introduced, has high hydrophilicity, and is capable of efficiently recovering boron.　This cellulose derivative has a repeating unit represented by formula (I-1) below. In formula (I-1), Ra's are the same or different and are each a hydroxyl group, or a group represented by formula (a) below. In formula (a), R1represents a hydrogen atom or a methyl group. R2represents a hydrogen atom, or a hydrocarbon group which may have a hydroxyl group. R3represents a hydrogen atom or a hydrocarbon group. In addition, at least one of all Ra's contained in the cellulose derivative is a group represented by formula (a) below.

IPC Classes  ?

• C08B 3/14 - Preparation of cellulose esters of organic acids in which the organic acid residue contains substituents, e.g. NH2, Cl
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C08F 8/30 - Introducing nitrogen atoms or nitrogen-containing groups

Abstract

The present invention relates to a cyber-physical system for optimizing a simulation model for chemical mechanical polishing based on actual measurement data of chemical mechanical polishing. The chemical mechanical polishing system includes a polishing apparatus (1) for polishing the workpiece (W) and an arithmetic system (47). The arithmetic system (47) includes a simulation model including at least a physical model configured to output an estimated polishing physical quantity including an estimated polishing rate of the workpiece (W). The arithmetic system (47) is configured to: input polishing conditions for the workpiece (W) into the simulation model; output the estimated polishing physical quantity of the workpiece (W) from the simulation model; and determine model parameters of the simulation model that bring the estimated polishing physical quantity closer to a measured polishing physical quantity of the workpiece (W).

IPC Classes  ?

• B24B 37/005 - Control means for lapping machines or devices
• B24B 53/017 - Devices or means for dressing, cleaning or otherwise conditioning lapping tools
• H01L 21/304 - Mechanical treatment, e.g. grinding, polishing, cutting

Abstract

A vibration power generation device that further improves power generation efficiency includes a vibration exciting body in which vibration is caused by a flowing fluid, a vibrated body that is oscillatable and connected to the vibration exciting body, and a power generator to generate electricity by oscillation of the vibrated body. The vibration exciting body is in proximity to a wall surface, and vibration is caused in the vibration exciting body by a fluid flowing along the wall surface.

IPC Classes  ?

• H02N 2/18 - Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing electrical output from mechanical input, e.g. generators

Abstract

The present invention provides a method for detecting a biomarker for detecting hepatocytes with bile ductular proliferation, said method comprising a step for detecting laminin γ2 single chain or a nucleic acid encoding the same as the biomarker in a specimen.

IPC Classes  ?

• C12Q 1/6813 - Hybridisation assays
• C12Q 1/686 - Polymerase chain reaction [PCR]
• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The purpose of the present disclosure is to provide a polysaccharide nanofiber-blended polysaccharide composition production method which can be implemented easily and by which it is possible to obtain a polysaccharide nanofiber-blended polysaccharide composition that has mechanical properties that are strengthened by polysaccharide nanofibers.　One aspect of an embodiment of the present disclosure is a polysaccharide nanofiber-blended polysaccharide composition production method comprising: a step for obtaining a mixture by mixing a sol containing polysaccharide nanofibers (A), a polysaccharide (B), and a solvent (C) capable of dissolving the polysaccharide (B); and a step for obtaining a dried mixture by drying the mixture.

IPC Classes  ?

• C08L 1/02 - CelluloseModified cellulose
• B29C 70/12 - Fibrous reinforcements only characterised by the structure of fibrous reinforcements using fibres of short length, e.g. in the form of a mat
• C08B 11/02 - Alkyl or cycloalkyl ethers
• C08B 11/08 - Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with hydroxylated hydrocarbon radicalsEsters, ethers, or acetals thereof
• C08B 11/12 - Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals substituted with carboxylic radicals
• C08B 30/00 - Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
• C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
• C08L 3/02 - StarchDegradation products thereof, e.g. dextrin
• D01F 2/28 - Monocomponent artificial filaments or the like of cellulose or cellulose derivativesManufacture thereof from cellulose derivatives from organic cellulose esters or ethers, e.g. cellulose acetate

Abstract

A magnetostrictive power generation element (1) comprises: a magnetostrictive body unit (2) at least partially having a magnetostrictive body; a magnet for applying a magnetic bias to the magnetostrictive body; a coil; and a bobbin (5) having a hollow portion (5b) and housing at least a part of the magnetostrictive body in the hollow portion (5b). The bobbin (5) has a wound portion (5c), around which the coil is wound, on the outer periphery of a region in which the hollow portion (5b) is provided.

IPC Classes  ?

• H02N 2/18 - Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing electrical output from mechanical input, e.g. generators
• H01F 5/02 - Coils wound on non-magnetic supports, e.g. formers

Abstract

Provided are a fine particle adsorption material and removal method that enable sufficient removal of fine particles from a solvent having a low water content. This fine particle adsorption material is for adsorbing and removing fine particles from a solvent containing the fine particles. The material has a graft chain that is a negatively charged group. A polymer material that serves as a base material for the fine particle adsorption material is an aliphatic hydrocarbon, or an aliphatic hydrocarbon containing fluorine or chlorine. This method for removing fine particles from a solvent comprises bringing said fine particle adsorption material into contact with the solvent, and thereby causing the fine particles in the solvent to be adsorbed by the fine particle adsorption material and to be removed from the solvent.

IPC Classes  ?

• B01D 15/00 - Separating processes involving the treatment of liquids with solid sorbentsApparatus therefor
• B01D 15/04 - Separating processes involving the treatment of liquids with solid sorbentsApparatus therefor with ion-exchange materials as adsorbents
• B01J 39/05 - Processes using organic exchangers in the strongly acidic form
• B01J 39/20 - Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
• B01J 47/12 - Ion-exchange processes in generalApparatus therefor characterised by the use of ion-exchange material in the form of ribbons, filaments, fibres or sheets, e.g. membranes
• B01J 47/127 - Ion-exchange processes in generalApparatus therefor characterised by the use of ion-exchange material in the form of ribbons, filaments, fibres or sheets, e.g. membranes in the form of filaments or fibres
• B01J 20/26 - Synthetic macromolecular compounds

Abstract

A fuel cell system having a direct liquid fuel cell that uses a liquid containing a formic acid or an alcohol as a fuel includes: a fuel tank that stores the fuel to be supplied to the fuel cell; a fuel supply device that supplies the fuel in the fuel tank to the fuel cell; and a bubbling device that blows an inert gas into the fuel stored in the fuel tank.

IPC Classes  ?

• H01M 8/04 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids
• H01M 8/04186 - Arrangements for control of reactant parameters, e.g. pressure or concentration of liquid-charged or electrolyte-charged reactants
• H01M 8/04746 - PressureFlow
• H01M 8/0668 - Removal of carbon monoxide or carbon dioxide
• H01M 8/1011 - Direct alcohol fuel cells [DAFC], e.g. direct methanol fuel cells [DMFC]

Abstract

The present invention provides a composition for regulating carbohydrate metabolism, the composition containing, as an active ingredient, an agent for controlling the amount of D-amino acid in the living body of a subject. Moreover, the present invention provides a method for assessing carbohydrate metabolism conditions of a subject by monitoring the amount of D-amino acid in the living body of the subject.

IPC Classes  ?

• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61P 3/08 - Drugs for disorders of the metabolism for glucose homeostasis
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• A61P 9/12 - Antihypertensives
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A23L 33/175 - Amino acids

Abstract

A kneading state detection device (50) comprises: an AE wave acquisition unit (71) (acquisition unit) that acquires, when a twin-screw extruder (30) (extruder) for kneading a raw material or kneading a raw material with an additive is in operation, an AE output (M(t)) of an AE sensor (20) installed in a housing (32) of the twin-screw extruder (30); and a kneading state determination unit (72) (determination unit) that determines the kneading state of the raw material on the basis of a comparison between a change in the intensity of the AE output (M(t)) of the AE sensor (20) acquired by the AE wave acquisition unit (71) and a threshold value (Th).

IPC Classes  ?

• G01N 29/14 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic wavesVisualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object using acoustic emission techniques
• B29B 7/22 - Component parts, details or accessoriesAuxiliary operations
• B29B 7/58 - Component parts, details or accessoriesAuxiliary operations
• B29C 48/40 - Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders using two or more parallel screws, e.g. twin screw extruders
• B29C 48/92 - Measuring, controlling or regulating

Abstract

Provided is a method that enables industrially efficient production of an esterified polysaccharide product. A method for producing an esterified polysaccharide product, the method including reacting a polysaccharide-containing biomass, a basic ionic liquid with a pKa of a conjugate acid of an anion from 2 to 19 as a calculated value in a vacuum, and an esterifying agent using a kneader equipped with a shear force application mechanism. A cation constituting the basic ionic liquid is preferably one selected from the group consisting of an imidazolium cation, a pyridinium cation, and a tetraalkylammonium cation.

IPC Classes  ?

• C08B 3/06 - Cellulose acetate
• B29C 48/40 - Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders using two or more parallel screws, e.g. twin screw extruders

Abstract

A production method for a low molecular weight polymer suitable for a melt-blown non-woven fabric and a production device for melt-blown non-woven fabric, with which a high molecular weight polymer can be reduced in molecular weight by applying a shear force to the high molecular weight polymer without adding an additive. The low molecular weight polymer and the melt-blown non-woven fabric are produced using a continuous high shearing device that applies a shear force to the high molecular weight polymer serving as a raw material by rotation of a screw body to reduce the molecular weight of the high molecular weight polymer so as to obtain a low molecular weight polymer, and cools the low molecular weight polymer by passing the low molecular weight polymer through a passage arranged in the axial direction inside the screw body.

IPC Classes  ?

• D04H 1/56 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving in association with fibre formation, e.g. immediately following extrusion of staple fibres
• B29C 48/88 - Thermal treatment of the stream of extruded material, e.g. cooling
• B29C 48/86 - Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling at the nozzle zone
• B29C 48/30 - Extrusion nozzles or dies
• B29C 48/05 - Filamentary, e.g. strands
• B29C 48/285 - Feeding the extrusion material to the extruder
• B29B 7/48 - MixingKneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
• B29B 7/72 - Measuring, controlling or regulating
• B29B 7/82 - Heating or cooling
• D04H 1/4291 - Olefin series

Abstract

A signal acquisition unit of an abnormality detection device for a twin-screw extrusion molding machine, when the twin-screw extrusion molding machine that melts and kneads a fed resin raw material is in operation, acquires an AE output of an AE sensor installed on a surface of a housing of the twin-screw extrusion molding machine. A determination unit determines whether an abnormality occurs in the twin-screw extrusion molding machine, based on a relationship between the AE output and a first threshold and a second threshold.

IPC Classes  ?

• B29C 48/92 - Measuring, controlling or regulating
• G01M 99/00 - Subject matter not provided for in other groups of this subclass

Abstract

A fuel cell system (1) comprises: a fuel cell (10); a power recovery device (30); and a control device (20) that controls the fuel cell (10) and the power recovery device (30). In a state in which the supply of liquid fuel to the fuel cell (10) has been stopped, by carrying out charging with post-stoppage power generated by the fuel cell (10) using liquid fuel that was already supplied, the control device (20) causes the power recovery device (30) to recover the post-stoppage power, and after the same has been recovered, the control device stops electrode reactions in an electrode structure of the fuel cell (10).

IPC Classes  ?

• H01M 8/04228 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids during start-up or shut-downDepolarisation or activation, e.g. purgingMeans for short-circuiting defective fuel cells during shut-down
• H01M 8/04 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids
• H01M 8/04303 - Processes for controlling fuel cells or fuel cell systems applied during specific periods applied during shut-down
• H01M 8/0438 - PressureAmbient pressureFlow
• H01M 8/04537 - Electric variables
• H01M 8/04858 - Electric variables
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

Provided are a fine particle production apparatus and a fine particle production method that can control the particle sizes of fine particles, and efficiently produce a large amount of fine particles having good particle size uniformity. The present invention comprises: a raw material supply unit which supplies raw materials for fine particle production into thermal plasma flame; a plasma torch in which the thermal plasma flame is generated, and which evaporates the raw material supplied by the raw material supply unit by means of the thermal plasma flame to form a mixture in a gas phase state; and a plasma generation unit which generates thermal plasma flame inside the plasma torch. The plasma generation unit includes: a first coil which surrounds the plasma torch, a second coil which is installed below the first coil in the longitudinal direction of the plasma torch and surrounds the circumference of the plasma torch; a first power supply unit which supplies an amplitude-modulated first high-frequency current to the first coil; and a second power supply unit which supplies an amplitude-modulated second high-frequency current to the second coil. The degree of modulation of the first high-frequency current is smaller than the degree of modulation of the second high-frequency current.

IPC Classes  ?

• B22F 9/14 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes using electric discharge
• B22F 9/12 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from gaseous material
• H05H 1/42 - Plasma torches using an arc with provisions for introducing materials into the plasma, e.g. powder or liquid

Abstract

Described herein are sulfonamide derivatives of Formula (I) capable of inhibiting RNA dependent RNA polymerase (RdRP) activity of cancer cells. Also described are pharmaceutical compositions comprising these compounds and the uses thereof in the prophylaxis and/or treatment of cancers, including intractable solid cancers and stem cells cancer. The pharmaceutical composition may further comprise at least one of an hormonal therapeutic agent, a chemotherapeutic agent, an immunotherapeutic agent, a pharmaceutical agent inhibiting the action of cell growth factor and a pharmaceutical agent inhibiting the action of cell growth factor receptor.

IPC Classes  ?

• A61K 31/47 - QuinolinesIsoquinolines
• A61P 35/00 - Antineoplastic agents
• C07D 215/20 - Oxygen atoms

Abstract

A purpose of the present invention is to provide a cellulose nanofiber composition which, in a dried state, has excellent redispersibility. The cellulose nanofiber composition comprises modified cellulose nanofibers having an ionic functional group and a betaine compound having a molecular weight of 600 or less. The betaine compound is contained in an amount of preferably 5-1,000 parts by mass per 100 parts by mass of the modified cellulose nanofibers.

IPC Classes  ?

• C08L 1/08 - Cellulose derivatives
• C08B 15/04 - Carboxycellulose, e.g. prepared by oxidation with nitrogen dioxide
• C08J 3/03 - Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
• C08J 3/16 - Powdering or granulating by coagulating dispersions
• C08K 5/19 - Quaternary ammonium compounds

Abstract

This atomic force microscope (10) comprises a cantilever (11) provided with a downwardly protruding probe (12), a sample holding part (18) that holds a sample (99) such that the sample faces the cantilever (11), a drive unit (17) that drives at least one from among the cantilever (11) and sample holding part (18) such that the sample (99) moves in relation to the probe (12), and a control unit (for example, a PC (15)) that controls the drive unit (17) such that the surface of the sample (99) is scanned by the probe (12). In first direction scanning in which the sample (99) is moved from one end side to the other end side in relation to the probe (12), the control unit brings the sample (99) and probe (12) together to a first distance and scans the sample (99) at a first speed. In second direction scanning in which the sample (99) is moved from the other end side to the one end side in relation to the probe (12), the control unit moves the sample (99) and probe (12) apart to a second distance further than the first distance and scans the sample (99) at a second speed faster than the first speed.

IPC Classes  ?

• G01Q 10/04 - Fine scanning or positioning
• G01Q 60/32 - AC mode

Abstract

Provided is a composition for promoting secretion of extracellular vesicles, which comprises a compound having a structure of the formula I (wherein each substituent is as defined in the specification), a racemate thereof or a stereoisomer thereof, or a salt thereof, or a compound having a structure of the formula II (wherein each substituent is as defined in the specification), or a stereoisomer thereof, or a salt thereof, or, cucurbitacin, or a stereoisomer thereof, or a salt thereof.

IPC Classes  ?

• C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells

Abstract

An object of the present invention is to provide a method for producing a polysaccharide derivative in which the use of a reagent such as an acid catalyst is not needed and a reaction can be smoothly progressed without causing any side reactions. A method for producing a polysaccharide derivative of the present invention includes a step of dissolving a raw material including a polysaccharide in at least one ionic liquid having an anion which is a non-carboxylate anion and reacting the raw material with an acyl group donor, a conjugate acid of the anion having a pKa of 4 or higher in vacuum.

IPC Classes  ?

• C08B 3/10 - Preparation of cellulose esters of organic acids of monobasic organic acids with three or more carbon atoms with five or more carbon atoms

Abstract

A method for causing a qualitative change in muscle fibers of a human or animal individual, includes the oral administration of a feed incorporating fermentation product dissolving solutions of thermophilic bacteria or Bacillus hisashn NITE BP-863 obtained by aeration treatment of a high-temperature fermentation product containing complex bacteria ATCC PTA-1773 as an active ingredient to the human or animal individual.

IPC Classes  ?

• A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system

Abstract

A fine particle manufacturing apparatus and a fine particle manufacturing method are provided. The apparatus includes a raw material supply part supplying a raw material; a plasma torch in which the thermal plasma flame is generated and the raw material supplied by the raw material supply part is vaporized by using the thermal plasma flame to form a mixture in a gas phase state; and a plasma generation part generating the thermal plasma flame inside the plasma torch. The plasma generation part includes a first coil encircling the plasma torch; a second coil encircling the plasma torch and disposed below the first coil; a first power supply part supplying a high-frequency electric current to the first coil; and a second power supply part supplying an amplitude-modulated high-frequency electric current to the second coil. The first coil and the second coil are arranged in the longitudinal direction of the plasma torch.

IPC Classes  ?

• H05H 1/30 - Plasma torches using applied electromagnetic fields, e.g. high-frequency or microwave energy
• B01J 19/08 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor
• C01B 33/021 - Preparation

Abstract

The invention provides a composition for suppressing secretion of extracellular vesicle, which comprises a compound having a structure of the formula II (wherein, each substituent is as defined in the specification), or a pharmaceutically acceptable salt thereof, or a compound having a structure of the formula I (wherein, each substituent is as defined in the specification), or a metal complex thereof, or a pharmaceutically acceptable salt thereof.

IPC Classes  ?

• A61K 31/409 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
• A61P 35/00 - Antineoplastic agents
• A61K 31/404 - Indoles, e.g. pindolol

Abstract

This fuel battery comprises a discharge structure (F) which externally discharges produced water that is produced at a cathode electrode by an electrode reaction in an MEA (40). The discharge structure (F) is provided with: a discharge path (28) through which air that is an oxidant is to flow; a passage (29) which connects the discharge path (28) with an oxidant supply passage (21) so as to enable communication therebetween and which moves, to the discharge path (28), the produced water that has been produced at the cathode electrode; and a discharge unit (20c) which externally discharges the produced water that has been moved to the discharge path (28).

IPC Classes  ?

• H01M 8/0258 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant
• H01M 8/0263 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant having meandering or serpentine paths
• H01M 8/04 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids
• H01M 8/04746 - PressureFlow
• H01M 8/10 - Fuel cells with solid electrolytes
• H01M 8/1009 - Fuel cells with solid electrolytes with one of the reactants being liquid, solid or liquid-charged

Abstract

Provided is an adsorbing material which is produced using a low environmental load material as a raw material, and adsorbs selenious acid selectively and efficiently.　A selenious acid-adsorbing material according to the present disclosure contains a cellulose derivative (I) having a repeating unit represented by formula (I). In the formula, Rais a hydrogen atom, a group represented by formula (a-1), or a group represented by formula (a-2). Moreover, at least one among all of Ra's contained in the cellulose derivative is a group represented by formula (a-1) or a group represented by formula (a-2).

IPC Classes  ?

• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• B01J 20/26 - Synthetic macromolecular compounds
• B01J 20/30 - Processes for preparing, regenerating or reactivating

Abstract

[Problem] To provide a mold, a molding system, and a mold manufacturing method which make it possible to easily and effectively spread mold release components of a mold release agent onto an inner surface of a mold without degrading the mold release agent, even with oil-based mold release agents, and which can achieve high manufacturing efficiency. [Solution] A pair of molds for molding a molded product in a gap therebetween is caused to be provided with a liquid path portion and a liquid infiltration layer configured by melting and solidifying metal powders, and a mold release agent is caused to be infiltrated into the gap. Specifically, the liquid infiltration layer is caused to be a thin layer having, at a high density, a liquid infiltration tube which is communicated with the molded surface and has a minute diameter. The liquid path portion is caused to have a 3D mesh structure having a meshed thin shaft, and is arranged along the liquid infiltration layer. The mold release agent is distributed while being in contact with the 3D mesh structure, thereby exerting such an advantageous effect that the mold release agent is not heated unevenly, and deterioration thereof is suppressed. When a form is adopted in which melting and solidifying are not performed with an axial direction of the thin shaft horizontal, this is preferable because easy melting and solidifying are achieved without breaking the thin shaft.

IPC Classes  ?

• B22D 17/20 - AccessoriesPressure die casting or injection die casting, i.e. casting in which the metal is forced into a mould under high pressure Details
• B22D 17/22 - DiesDie platesDie supportsCooling equipment for diesAccessories for loosening and ejecting castings from dies
• B22F 3/105 - Sintering only by using electric current, laser radiation or plasma
• B22F 3/16 - Both compacting and sintering in successive or repeated steps
• B33Y 10/00 - Processes of additive manufacturing
• B29C 33/58 - Applying the releasing agents

Abstract

Provided is a cellulose derivative that has excellent storage stability and that can selectively adsorb valuable metals and toxic metals.　The cellulose derivative according to the present invention has a repeating unit represented by formula (I). In formula (I), Ras are identical or different from each other, and each represent a hydrogen atom or a group represented by formula (a). In formula (a), ring Z represents a heterocyclic ring including a nitrogen atom as a heteroatom, and R1represents a single bond or an alkylene group having 1-10 carbon atoms. The four R2s are identical or different from each other, and each represent an alkyl group having 1-10 carbon atoms. It should be noted that, of all Ras included in the cellulose derivative, at least one is a group represented by formula (a).

IPC Classes  ?

• B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C08B 3/14 - Preparation of cellulose esters of organic acids in which the organic acid residue contains substituents, e.g. NH2, Cl

Abstract

The present invention provides: a marker for determining critical stage kidney disease by using an indicator value based on the amount of D-alanine in the blood or the amount of D-alanine and L-alanine therein; a blood analysis method which uses said marker for patients undergoing surgery or intensive care; and a blood analysis system for determining critical stage kidney disease in patients undergoing surgery or intensive care.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• G01N 33/70 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving creatine or creatinine

Abstract

A power generation element and an actuator for vibration power generation is provided that can be mass-produced at low cost while achieving increase in electromotive force. A power generation element includes a main series magnetic circuit having a frame yoke made of magnetic material and provided with a fixed portion that is one end and a free portion that is the other end across a U-shaped bent portion, a main magnet that applies a magnetic bias to the frame yoke, and a first gap formed at a position in contact with the free portion; and an auxiliary series magnetic circuit having an auxiliary yoke made of magnetic material and attached to the frame yoke, an auxiliary magnet that gives a magnetic bias to the auxiliary yoke, a second gap formed at a position facing the first gap across the free portion, the frame yoke, the main magnet, and the first gap. The amount of change in a main magnetic flux passing in a coil wound around the frame yoke increases when the free portion vibrates due to application of an external force and a magnetic resistance of the first gap and a magnetic resistance of the second gap increase or decrease reciprocally.

IPC Classes  ?

• H10N 35/00 - Magnetostrictive devices

Abstract

[Problem] To provide a novel semiconductor device for high-voltage purposes having no drift layer. [Solution] The semiconductor device of the present invention comprises: a first semiconductor layer of a first conductivity type which is either p-type or n-type; a source portion comprising a semiconductor portion of a second conductivity type which is disposed in contact with the first semiconductor layer, the second conductivity type being different from the first conductivity type; a source electrode disposed in ohmic contact with the source portion; a gate electrode disposed in one of surfaces of the first semiconductor layer with a gate insulating film therebetween, and capable of forming, by means of an applied electric field, an inversion layer in a region of the first semiconductor layer in the vicinity of the surface thereof contacting the gate insulating film; a second semiconductor layer of the first conductivity type disposed in contact with the inversion layer; and a drain electrode spaced apart from the inversion layer and disposed in Schottky contact with the second semiconductor layer.

IPC Classes  ?

• H01L 29/78 - Field-effect transistors with field effect produced by an insulated gate
• H01L 29/16 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only elements of Group IV of the Periodic System in uncombined form

Abstract

Provided are a fine particle manufacturing apparatus and a fine particle manufacturing method, which manufacture smaller fine particles. The fine particle manufacturing apparatus has: a raw material supply unit that supplies raw materials for producing fine particles into a thermal plasma flame; a plasma torch in which the thermal plasma flame is generated and the raw materials supplied by the raw material supply unit is evaporated by the thermal plasma flame to form a mixture in a gaseous state; a plasma generation unit that generates the thermal plasma flame inside the plasma torch; and a gas supply unit that supplies quenched gas to the thermal plasma flame, wherein the gas supply unit supplies the quenched gas with time modulation of the supply amount of the quenched gas.

IPC Classes  ?

• B01J 19/08 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor
• B01J 2/04 - Processes or devices for granulating materials, in generalRendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
• B22F 9/14 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes using electric discharge
• C01B 33/027 - Preparation by decomposition or reduction of gaseous or vaporised silicon compounds other than silica or silica-containing material
• H05H 1/30 - Plasma torches using applied electromagnetic fields, e.g. high-frequency or microwave energy

Abstract

The present invention relates to a cyber-physical system which optimizes a simulation model for chemical-mechanical polishing, on the basis of actual measurement data of chemical-mechanical polishing. The chemical-mechanical polishing system is provided with a polishing device (1) which polishes a workpiece (W), and a computation system (47). The computation system (47) has a simulation model which includes at least a physical model which outputs estimated polishing physical quantities including an estimated polishing rate of the workpiece (W). The computation system (47) inputs polishing conditions of the workpiece (W) into the simulation model and outputs the estimated polishing physical quantities of the work piece (W) from the simulation model, and determines model parameters of the simulation model which approximate the estimated polishing physical quantities to the actually measured polishing physical quantities of the workpiece (W).

IPC Classes  ?

• B24B 37/005 - Control means for lapping machines or devices
• B24B 53/017 - Devices or means for dressing, cleaning or otherwise conditioning lapping tools
• H01L 21/304 - Mechanical treatment, e.g. grinding, polishing, cutting

Abstract

[Problem] To provide a polyrotaxane having high heat resistance. [Solution] A polyrotaxane having a straight-chain molecule, a ring molecule encircling the straight-chain molecule in a skewered manner, and a blocking group disposed at both terminals of the straight-chain molecule, the polyrotaxane being characterized in that the ring molecule includes an aromatic ring having a phenol hydroxyl group in a side chain. The polyrotaxane can be manufactured via a manufacturing method that includes: a step for dissolving, in a solvent including methanol, a straight-chain molecule and a ring molecule that includes an aromatic ring having a phenol hydroxyl group in a side chain and obtaining a pseudo-polyrotaxane in which a ring molecule encircles the straight-chain molecule in a skewered manner; and a step for dissolving, in a solvent, the pseudo-polyrotaxane and a blocking group material and disposing the blocking group on both terminals of the straight-chain molecule.

IPC Classes  ?

• C07C 39/15 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings
• C08G 65/332 - Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides or esters thereof
• C08G 65/333 - Polymers modified by chemical after-treatment with organic compounds containing nitrogen
• C07C 37/00 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring

Abstract

Provided is a laser cleaving method which, in processing of sapphire having a thickness of not less than several millimeters, reduces working time etc. and achieves high-quality parting. A laser light source 103 emits a laser beam 3 at a wavelength for which a sapphire plate 1 has a light absorbance of not less than 1% but less than 50%, and thermal stress which has been generated by the emission of the laser beam 3 is used to carry out cleavage by causing a crack to develop inside the sapphire plate 1, starting from a minute defect that is provided in the sapphire plate 1. The laser light source 103 emits a laser beam 3 which has a laser output power of not less than 60 W.

IPC Classes  ?

• B28D 5/00 - Fine working of gems, jewels, crystals, e.g. of semiconductor materialApparatus therefor
• B23K 26/50 - Working by transmitting the laser beam through or within the workpiece
• B23K 26/60 - Preliminary treatment
• B26F 3/06 - Severing by using heat

Abstract

To provide extracellular vesicles capable of satisfactorily activating, etc., antigen-specific T cells. Provided are said antigen-presenting extracellular vesicles that present an antigen-presenting MHC molecule and a T-cell-stimulating cytokine extramembranously.

IPC Classes  ?

• A61K 38/19 - CytokinesLymphokinesInterferons
• A61P 35/00 - Antineoplastic agents
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• A61P 37/08 - Antiallergic agents
• C07K 14/52 - CytokinesLymphokinesInterferons
• C07K 14/74 - Major histocompatibility complex [MHC]
• C07K 19/00 - Hybrid peptides
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/19 - InterferonsLymphokinesCytokines
• C12N 15/62 - DNA sequences coding for fusion proteins
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

To provide extracellular vesicles capable of satisfactorily activating, etc., antigen-specific T cells.　Provided are said antigen-presenting extracellular vesicles that present an antigen-presenting MHC molecule and a T-cell-stimulating cytokine extramembranously.

IPC Classes  ?

• A61P 35/00 - Antineoplastic agents
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• A61P 37/08 - Antiallergic agents
• C07K 14/52 - CytokinesLymphokinesInterferons
• C07K 14/74 - Major histocompatibility complex [MHC]
• C07K 19/00 - Hybrid peptides
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/19 - InterferonsLymphokinesCytokines
• C12N 15/62 - DNA sequences coding for fusion proteins
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• A61K 38/19 - CytokinesLymphokinesInterferons
• A61K 35/15 - Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cellsMyeloid precursor cellsAntigen-presenting cells, e.g. dendritic cells

Abstract

To provide a polynucleotide that makes it possible to produce extracellular vesicles capable of satisfactorily activating, etc., antigen-specific T cells.　Provided is a polynucleotide including at least one sequence selected from the group consisting of (a) a sequence encoding a fusion protein (A) including an antigen-presenting MHC molecule and capable of presenting the antigen-presenting MHC molecule extramembranously of an extracellular vesicle; (b) a sequence encoding a fusion protein (B) including at least one T cell stimulating cytokine or a subunit thereof and capable of presenting the T cell stimulating cytokine extramembranously of an extracellular vesicle; (c) a sequence encoding a fusion protein (C) including a T cell co-stimulatory molecule and capable of presenting the T cell co-stimulatory molecule extramembranously of an extracellular vesicle; (d) a sequence encoding a fusion protein (D) including an antigen-presenting MHC molecule and at least one T cell stimulating cytokine or a subunit thereof and capable of presenting the antigen and the T cell stimulating cytokine extramembranously of an extracellular vesicle; (e) a sequence encoding a fusion protein (E) including an antigen-presenting MHC molecule, at least one T cell stimulating cytokine or a subunit thereof, and a T cell co-stimulatory molecule and capable of presenting the antigen, the T cell stimulating cytokine, and the T cell co-stimulatory molecule extramembranously of an extracellular vesicle.

IPC Classes  ?

• C12N 15/62 - DNA sequences coding for fusion proteins
• A61K 35/15 - Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cellsMyeloid precursor cellsAntigen-presenting cells, e.g. dendritic cells
• A61K 38/19 - CytokinesLymphokinesInterferons
• A61P 35/00 - Antineoplastic agents
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• A61P 37/08 - Antiallergic agents
• C07K 14/52 - CytokinesLymphokinesInterferons
• C07K 14/74 - Major histocompatibility complex [MHC]
• C07K 19/00 - Hybrid peptides
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/19 - InterferonsLymphokinesCytokines
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, a kidney inflammation inhibitor, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-alanine or a derivative thereof. In addition, the present invention pertains to the use of D-alanine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.

IPC Classes  ?

• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys

Abstract

The present invention provides a method for producing a silyl etherified product of a polysaccharide, said method using no highly corrosive reagent, while generating no highly corrosive by-product, no salt that is hard to process, and the like. A method for producing a silyl etherified product of a polysaccharide, said method comprising a step wherein a polysaccharide is reacted with a hydrosilane compound or a carboxylic acid silyl ester in dimethyl sulfoxide in the presence of a quaternary ammonium salt having anions that correspond to an acid having an acid dissociation constant pKa of from 12 to 19, thereby silyl etherifying a hydroxyl group of the polysaccharide. The reaction between the polysaccharide and the hydrosilane compound may be carried out in a carbon dioxide atmosphere.

IPC Classes  ?

• C08B 11/00 - Preparation of cellulose ethers

Abstract

It is an object of the present invention to obtain a novel composite material excellent in terms of flexibility and thermoformability from a lignocellulosic biomass as a raw material. It is an object of the present invention to obtain a novel composite material excellent in terms of flexibility and thermoformability from a lignocellulosic biomass as a raw material. A composite material, in which some hydroxy groups of a lignocellulosic biomass are esterified, which is characterized in that the esterified portion has short-chain acyl groups containing 2 to 4 carbon atoms and long-chain acyl groups containing 3 to 18 carbon atoms.

IPC Classes  ?

• C08H 8/00 - Macromolecular compounds derived from lignocellulosic materials
• C08L 97/02 - Lignocellulosic material, e.g. wood, straw or bagasse

Abstract

Provided are: a method which is for producing a low-molecular-weight polymer suitable for a melt-blown non-woven fabric, and by which a low-molecular-weight polymer can be efficiently produced by applying a shearing force to a high-molecular-weight polymer without adding an additive such as a peroxide which promotes a pyrolysis reaction, to thereby reduce the molecular weight of the high-molecular-weight polymer; and a device for producing a melt-blown non-woven fabric. A low-molecular-weight polymer and a melt-blown non-woven fabric are produced by using a continuous high-shearing processing device which applies a shearing force to a high-molecular-weight polymer as a raw material through the rotation of a screw main body 37 and thereby reduces the molecular weight thereof to produce a low-molecular-weight polymer, and which cools the low-molecular-weight polymer by allowing the low-molecular-weight polymer to pass through a passage 88 provided in the axial direction inside the screw main body 37.

IPC Classes  ?

• C08J 3/00 - Processes of treating or compounding macromolecular substances
• D04H 1/4291 - Olefin series
• D04H 1/54 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving
• B29C 48/05 - Filamentary, e.g. strands

Abstract

−1 volume % or less of the nitrogen gas or the nitride gas, and the diamond crystal layer having the nitrogen-vacancy centers is formed. A method for manufacturing a diamond substrate to form an underlying substrate, a diamond crystal having a dense nitrogen-vacancy centers (NVCs) with an orientation of NV axis by performing the CVD.

IPC Classes  ?

• C30B 29/04 - Diamond
• C23C 16/02 - Pretreatment of the material to be coated
• C23C 16/27 - Diamond only
• C30B 25/18 - Epitaxial-layer growth characterised by the substrate
• H01F 1/40 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties of inorganic materials of magnetic semiconductor materials, e.g. CdCr2S4
• C30B 25/20 - Epitaxial-layer growth characterised by the substrate the substrate being of the same materials as the epitaxial layer
• H01F 10/10 - Thin magnetic films, e.g. of one-domain structure characterised by magnetic layers characterised by the composition
• C01B 32/25 - Diamond

Abstract

This fuel cell system includes a direct liquid fuel cell that uses, as a fuel, a liquid containing formic acid or alcohol. The fuel cell system includes: a fuel tank for storing a fuel that is supplied to the fuel cell; a fuel supply device that supplies the fuel in the fuel tank to the fuel cell; and a bubbling device that blows an inert gas into the fuel stored in the fuel tank.

IPC Classes  ?

• H01M 8/04 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids
• H01M 8/04186 - Arrangements for control of reactant parameters, e.g. pressure or concentration of liquid-charged or electrolyte-charged reactants
• H01M 8/043 - Processes for controlling fuel cells or fuel cell systems applied during specific periods
• H01M 8/04701 - Temperature
• H01M 8/04746 - PressureFlow
• H01M 8/04791 - ConcentrationDensity
• H01M 8/10 - Fuel cells with solid electrolytes
• H01M 8/1009 - Fuel cells with solid electrolytes with one of the reactants being liquid, solid or liquid-charged
• H01M 8/1011 - Direct alcohol fuel cells [DAFC], e.g. direct methanol fuel cells [DMFC]

Abstract

This fuel cell system has a direct-liquid-type fuel cell that uses a liquid including formic acid or an alcohol as fuel, wherein the fuel cell has a fuel electrode, an air electrode, and an electrolyte film, and the fuel electrode has a fuel inlet port through which fuel is supplied and a fuel outlet port through which fuel is discharged. The fuel cell system includes: a fuel-supply and cleaning device that supplies fuel toward the fuel inlet port or supplies a cleaning fluid toward the fuel inlet port to clean the fuel electrode; and a control device that performs switching between the cleaning of the fuel electrode and the fuel supply carried out by the fuel-supply and cleaning device.

IPC Classes  ?

• H01M 8/008 - Disposal or recycling of fuel cells
• H01M 8/04 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids
• H01M 8/043 - Processes for controlling fuel cells or fuel cell systems applied during specific periods
• H01M 8/04537 - Electric variables
• H01M 8/04746 - PressureFlow
• H01M 8/04858 - Electric variables
• H01M 8/10 - Fuel cells with solid electrolytes
• H01M 8/1011 - Direct alcohol fuel cells [DAFC], e.g. direct methanol fuel cells [DMFC]

Abstract

This fuel cell system includes: a direct liquid fuel cell which includes a fuel electrode that generates carbon dioxide when fuel is oxidized, and an air electrode that reduces oxygen; and fuel discharge piping for discharging fuel waste liquid containing carbon dioxide generated by the fuel electrode. The fuel discharge piping includes a carbon dioxide removing unit that removes cardon dioxide.

IPC Classes  ?

• H01M 8/04 - Auxiliary arrangements, e.g. for control of pressure or for circulation of fluids
• H01M 8/0668 - Removal of carbon monoxide or carbon dioxide
• H01M 8/10 - Fuel cells with solid electrolytes
• H01M 8/1011 - Direct alcohol fuel cells [DAFC], e.g. direct methanol fuel cells [DMFC]

Abstract

In the present invention, a fuel distribution groove formed in a fuel electrode current collector of a fuel electrode comprises: a plurality of distribution groove portions that are arranged in parallel to each other; and a plurality of folded-back groove portions, each of which connects between ends of one-side edges of two adjacent sets of the distribution groove portions or ends of the other-side edges thereof. Each of the folded-back groove portions has an inner wall surface that faces ends of distribution groove portions corresponding to the folded-back groove portion, and the inner wall surface has a curved surface shape in which the distance to the respective ends of the opposing distribution groove portions gradually decreases, in a direction orthogonal to the direction in which the distribution groove portions extend, toward both end of the inner wall surface.

IPC Classes  ?

• H01M 8/0258 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant
• H01M 8/026 - CollectorsSeparators, e.g. bipolar separatorsInterconnectors characterised by the configuration of channels, e.g. by the flow field of the reactant or coolant characterised by grooves, e.g. their pitch or depth
• H01M 8/10 - Fuel cells with solid electrolytes
• H01M 8/1011 - Direct alcohol fuel cells [DAFC], e.g. direct methanol fuel cells [DMFC]

Abstract

In order to provide a method by which luminescent nanocarbons that exhibit strong luminescence within a long wavelength region of from 500 nm to 620 nm when excited by light that has a wavelength shorter than the emission wavelength are able to be produced, a method for producing luminescent nanocarbons according to the present invention is provided with a reaction step wherein a starting material solution is reacted to form luminescent nanocarbons. With respect to this method for producing luminescent nanocarbons, the starting material solution contains: at least one compound that is selected from the group consisting of benzene compounds having a hydroxy group, aliphatic hydroxy acids and aliphatic dicarboxylic acids; and at least one compound selected from among o-phenylenediamine and 1, 5-naphthalenediamine.

IPC Classes  ?

• C09K 11/08 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials
• C09K 11/65 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing carbon
• B82Y 40/00 - Manufacture or treatment of nanostructures
• C01B 32/15 - Nanosized carbon materials

Abstract

The present invention provides a resin composition which enables an aliphatic polycarbonate to exhibit the mechanical properties thereof with good reproducibility, and which is formed into a molded body that has a good balance among mechanical properties such as strength, elongation and fracture toughness.　A resin composition according to the present invention contains an aliphatic polycarbonate and a polylactic acid; and with respect to the aliphatic polycarbonate, the area ratio of the region where the molecular weight is 20,000 or less to the entire molecular weight region in the molecular weight distribution curve of the aliphatic polycarbonate as obtained by size exclusion chromatography is from 1% to 30%.

IPC Classes  ?

• C08G 64/02 - Aliphatic polycarbonates
• C08G 64/34 - General preparatory processes using carbon dioxide and cyclic ethers
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08L 69/00 - Compositions of polycarbonatesCompositions of derivatives of polycarbonates
• C08J 5/00 - Manufacture of articles or shaped materials containing macromolecular substances

Abstract

According to the present invention, a signal acquisition unit (51a) (acquisition unit) of an abnormality detection device (50a) of a dual-axis extrusion molder (30) (extrusion molder) acquires an AE output (M(t)) of an AE sensor (20) installed on the surface of a housing (32) of the dual-axis extrusion molder (30) when the dual-axis extrusion molder (30) (extrusion molder) is in an operating state which melts and kneads an input resin raw material. In addition, a determination unit (53a) determines the occurrence of an abnormality in the dual-axis extrusion molder (30) on the basis of the relationship between the AE output (M(t)), a first threshold value (Th1), and a second threshold value (Th2).

IPC Classes  ?

• B29C 48/57 - Screws provided with kneading disc-like elements, e.g. with oval-shaped elements
• B29C 48/68 - Barrels or cylinders
• B29C 48/92 - Measuring, controlling or regulating
• B29C 48/96 - Safety devices