The United States of America, as represented by the Secretary, Department of Health and Human Services

United States of America

 
Total IP 2,832
Total IP Rank # 430
IP Activity Score 3.8/5.0    1,408
IP Activity Rank # 514

Patents

Trademarks

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Last Patent 2025 - Combination of angubindin-1 abd ...
First Patent 1982 - Method for reducing toxic effect...

Latest Inventions, Goods, Services

2024 Invention Neutralizing and protective monoclonal antibodies against respiratory syncytial virus (rsv). Anti...
Invention Influenza neuraminidase active site proximity assay (naspa) for rapid profiling of inhibitory ant...
Invention Immunogenic compositions comprising full-length influenza virus neuraminidase protein subunits an...
Invention Dna methylation-based cancer diagnostics. Disclosed herein are methods for classifying a tumor us...
Invention Prazole-based antiviral therapeutics. 161622nn- group where n is an integer from 1 to 6, a divale...
Invention Three-dimensional tuberculoma bioplatform and uses thereof. Provided herein is a 3-dimensional bi...
Invention Fused heterocycles for treating neurodegenerative diseases. Disclosed herein are aspects of compo...
Invention Nk cells or t cells expressing chimeric hematopoietic growth factor receptors and methods of use....
Invention Brincidofovir for treatment of multiple sclerosis. The invention features methods of treating mul...
Invention Bioreactor system. A bioreactor vessel platform for submersion in a bioreactor vessel or petri di...
Invention Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use. N-Lactoyl-Phenyla...
Invention A molecular scaffold for depleting hrpn13 and a select group of ken box proteins. The invention p...
Invention Gait assistance systems and methods of control thereof. Determining predicted torque values for a...
Invention Stabilized sars-cov-2 s antigens. Provided herein are engineered protein comprising stabilized co...
Invention Human parainfluenza virus immunogenic molecules. Disclosed are live-attenuated human parainfluenz...
Invention Codon-optimized human npc1 genes for the treatment of niemann-pick type c1 deficiency and related...
Invention Viral strain serology assays. The invention relates to methods and kits for determining a SARS-Co...
Invention Dopamine d3 receptor selective antagonists/partial agonists and uses thereof. Disclosed herein a...
Invention Polyfluorinated thalidomide analogs and uses thereof. Polyfluorinated thalidomide analogs have a ...
Invention Method and system for rapid spectral unmixing using spectrally interpolated background reduction....
Invention Rapid method for producing antibodies. The present disclosure relates to a rapid method for produ...
Invention Identification of sequence variants of the ervmer34-1 sequence family and use in anti-cancer ther...
Invention Bispecific antibodies that broadly target coronaviruses. Disclosed are bispecific antibodies, inc...
Invention 2b serotonin receptor antagonists, pharmaceutical compositions thereof, and methods of use thereo...
Invention Kinase inhibitors. Disclosed is a class of kinase inhibitors of formula (I) or formula (II). Rela...
Invention Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment ...
Invention Humanized 40h3 antibody. e.ge.g., humanized monoclonal antibodies and antigen binding fragments) ...
Invention Uses of iron chelators for treating stuttering. Provided herein are uses of iron chelators to tre...
Invention Potent and selective dopamine d3 receptor antagonists. 33 receptor modulators, inclusive of antag...
Invention Shipping container for system supporting live cells. A shipping container for the support and shi...
Invention Genetically detoxified mutant of neisseria and outer membrane vesicle (omv) vaccine. Disclosed ar...
Invention Novel malaria vaccine comprising ama1 and ron2 antigens. Plasmodium yoeliiPlasmodium falciparumPl...
Invention T cell receptors targeting ras with g12d, g12r, or g12v mutation. Disclosed are isolated or purif...
Invention Epidithiodiketopiperazine analogs and methods of use. Epidithiodiketopiperazine (ETP) analogs and...
Invention Method and apparatus for cryogenic-electron microscopy sample preparation. An apparatus for prepa...
Invention Vaccine for cats to block toxoplasma oocyst shedding and transmission. Apicomplexa or EuglenozoaT...
Invention Hiv-1 envelope triple tandem trimers and their use. Immunogens comprising a recombinant HIV-1 Env...
Invention Copiparvovirus genetic vector platform. In a first aspect, the invention provides a genetic vecto...
Invention Tyrosinase gene therapy for oculocutaneous albinism type 1a. TyrosinaseBESTROPHINVMD2TyrosinaseTy...
Invention Human monoclonal antibodies that target the rh5 complex of blood-stage plasmodium falciparum. P. ...
Invention Using machine learning and/or neural networks to validate stem cells and their derivatives (2-d c...
Invention Bicistronic chimeric antigen receptors and their uses. An embodiment of the invention provides c...
2023 Invention Combination of angubindin-1 abd chemotherapy for the treatment of cns malignancies. The invention...
Invention Fused diazepines as agonists of the insulin-like 3 (insl3) peptide receptor rxfp2 and methods of ...
Invention Preparation of isotopically labeled ketoglutarates and methods of hyperpolarization through signa...
2022 Invention Improved gene therapy constructs for the treatment of propionic acidemia caused by mutations in p...
Invention Next generation transpososomes. Disclosed herein is a modified transposase, comprising a core pi...
Invention Methods and systems for analyzing target engagement data from biological assays. The disclosure ...
Invention Self-assembling nanoparticles based on amphiphilic peptides. The present disclosure relates to a...
2021 Invention Therapeutics for the treatment of neurodegenerative disorders. Antisense oligonucleotides (ASOs)...