The United States of America, as represented by the Secretary, Department of Health and Human Services

États‑Unis d’Amérique

 
Quantité totale PI 2 815
Rang # Quantité totale PI 432
Note d'activité PI 3,8/5.0    1 423
Rang # Activité PI 508

Brevets

Marques

1 197 0
310 0
1 308 0
0
 
Dernier brevet 2025 - Nk cells or t cells expressing c...
Premier brevet 1982 - Method for reducing toxic effect...

Derniers inventions, produits et services

2024 Invention Fused heterocycles for treating neurodegenerative diseases. Disclosed herein are aspects of compo...
Invention Nk cells or t cells expressing chimeric hematopoietic growth factor receptors and methods of use....
Invention Brincidofovir for treatment of multiple sclerosis. The invention features methods of treating mul...
Invention Bioreactor system. A bioreactor vessel platform for submersion in a bioreactor vessel or petri di...
Invention Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use. N-Lactoyl-Phenyla...
Invention A molecular scaffold for depleting hrpn13 and a select group of ken box proteins. The invention p...
Invention Gait assistance systems and methods of control thereof. Determining predicted torque values for a...
Invention Stabilized sars-cov-2 s antigens. Provided herein are engineered protein comprising stabilized co...
Invention Human parainfluenza virus immunogenic molecules. Disclosed are live-attenuated human parainfluenz...
Invention Codon-optimized human npc1 genes for the treatment of niemann-pick type c1 deficiency and related...
Invention Viral strain serology assays. The invention relates to methods and kits for determining a SARS-Co...
Invention Dopamine d3 receptor selective antagonists/partial agonists and uses thereof. Disclosed herein a...
Invention Polyfluorinated thalidomide analogs and uses thereof. Polyfluorinated thalidomide analogs have a ...
Invention Method and system for rapid spectral unmixing using spectrally interpolated background reduction....
Invention Rapid method for producing antibodies. The present disclosure relates to a rapid method for produ...
Invention Identification of sequence variants of the ervmer34-1 sequence family and use in anti-cancer ther...
Invention Bispecific antibodies that broadly target coronaviruses. Disclosed are bispecific antibodies, inc...
Invention 2b serotonin receptor antagonists, pharmaceutical compositions thereof, and methods of use thereo...
Invention Kinase inhibitors. Disclosed is a class of kinase inhibitors of formula (I) or formula (II). Rela...
Invention Fully human monoclonal antibodies and chimeric antigen receptors against cd276 for the treatment ...
Invention Humanized 40h3 antibody. e.ge.g., humanized monoclonal antibodies and antigen binding fragments) ...
Invention Uses of iron chelators for treating stuttering. Provided herein are uses of iron chelators to tre...
Invention Potent and selective dopamine d3 receptor antagonists. 33 receptor modulators, inclusive of antag...
Invention Shipping container for system supporting live cells. A shipping container for the support and shi...
Invention Genetically detoxified mutant of neisseria and outer membrane vesicle (omv) vaccine. Disclosed ar...
Invention Novel malaria vaccine comprising ama1 and ron2 antigens. Plasmodium yoeliiPlasmodium falciparumPl...
Invention T cell receptors targeting ras with g12d, g12r, or g12v mutation. Disclosed are isolated or purif...
Invention Epidithiodiketopiperazine analogs and methods of use. Epidithiodiketopiperazine (ETP) analogs and...
Invention Method and apparatus for cryogenic-electron microscopy sample preparation. An apparatus for prepa...
Invention Vaccine for cats to block toxoplasma oocyst shedding and transmission. Apicomplexa or EuglenozoaT...
Invention Hiv-1 envelope triple tandem trimers and their use. Immunogens comprising a recombinant HIV-1 Env...
Invention Copiparvovirus genetic vector platform. In a first aspect, the invention provides a genetic vecto...
Invention Tyrosinase gene therapy for oculocutaneous albinism type 1a. TyrosinaseBESTROPHINVMD2TyrosinaseTy...
Invention Human monoclonal antibodies that target the rh5 complex of blood-stage plasmodium falciparum. P. ...
Invention Recombinant murine pneumonia virus expressing severe acute respiratory syndrome coronavirus 2 (sa...
Invention Using machine learning and/or neural networks to validate stem cells and their derivatives (2-d c...
Invention Single domain antibodies that specifically bind the s2 subunit of sars-cov-2 spike protein and co...
Invention Bicistronic chimeric antigen receptors and their uses. An embodiment of the invention provides c...
Invention Treatment of hypoparathyroidism using triphenyl calcilytic compounds. The present disclosure prov...
Invention Systems and methods for multichannel individualized stimulation therapy. Methods and systems are ...
Invention Synthetic mmab genes and aav vectors to treat cobalamin b deficiency. synMMABsynMMABsynMMAB polyn...
Invention Systems and methods for patterned multi-slice excitation in magnetic resonance imaging. Various m...
Invention 1-thioxo-2,4-dihydrothieno[2,3-e][1,2,4]triazolo[4,3-a]pyrimidin-5(1 h)-one derivatives as allost...
Invention Enzymatic radiosynthesis of deoxy-[18f]fluorocellobiose and deoxy-[18f]fluorocellotriose. Enzymat...
Invention T cell receptors targeting y220c or r175h mutation in p53. Disclosed are isolated or purified T c...
Invention Methods of preparing anti-human papillomavirus antigen t cells. Disclosed are methods of prepari...
2022 Invention Improved gene therapy constructs for the treatment of propionic acidemia caused by mutations in p...
Invention Next generation transpososomes. Disclosed herein is a modified transposase, comprising a core pi...
Invention Aqp1 gene therapy to prevent radiation induced salivary hypofunction. Administration of aquapori...
2021 Invention Therapeutics for the treatment of neurodegenerative disorders. Antisense oligonucleotides (ASOs)...