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2025
|
Invention
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Ribonucleic acids with 4'-thio-modified nucleotides and related methods.
Disclosed are messenger... |
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|
Invention
|
Lyophilized pharmaceutical compositions comprising a lipid nanoparticle.
Disclosed herein are no... |
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|
Invention
|
Ionizable cationic lipids.
Disclosed herein are novel compounds, pharmaceutical compositions com... |
|
|
Invention
|
Lipid nanoparticle compositions and methods for mrna delivery.
Disclosed herein are compositions... |
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|
Invention
|
Ice-based lipid nanoparticle formulations for delivery of mrna.
The present invention provides, ... |
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|
Invention
|
Vitamin cationic lipids.
Disclosed are cationic lipids comprising a vitamin substructure and an ... |
|
|
Invention
|
Composition and methods for treatment of ornithine transcarbamylase deficiency.
The present inve... |
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2024
|
Invention
|
Treatment of cystic fibrosis by delivery of nebulized mrna encoding cftr.
The present invention ... |
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|
Invention
|
Stable compositions of mrna-loaded lipid nanoparticles and processes of making.
The present inve... |
|
|
Invention
|
Stereochemically enriched compositions for delivery of nucleic acids.
Provided, in part, is a co... |
|
|
Invention
|
Ionizable cationic lipids. Disclosed herein are novel compounds, pharmaceutical compositions comp... |
|
|
Invention
|
Methods for purification of messenger rna using normal flow filtration.
The present invention pr... |
|
|
Invention
|
Thioester cationic lipids.
Disclosed are cationic lipids which are compounds of Formula (I), (II... |
|
|
Invention
|
Compositions, methods and uses of messenger rna.
The present invention provides, among other thi... |
|
|
Invention
|
Process of preparing mrna-loaded lipid nano particles.
The present invention provides an improve... |
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|
Invention
|
Process of preparing mrna-loaded lipid nanoparticles.
The present invention provides an improved... |
|
|
Invention
|
Cns delivery of mrna and uses thereof.
The present invention provides, among other things, metho... |
|
|
Invention
|
Composition and methods for treatment of primary ciliary dyskinesia.
The present invention provi... |
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|
Invention
|
Messenger rna therapy for treatment of articular disease.
The present invention provides, among ... |
|
|
Invention
|
Cationic polymers. Disclosed are cationic polymers comprising monomers such as those described in... |
|
|
Invention
|
Ribose cationic lipids.
Disclosed are cationic lipids which are compounds of Formula (I′).
Dis... |
|
|
Invention
|
Processes of preparing mrna-loaded lipid nanoparticles.
The present invention provides an improv... |
|
|
Invention
|
Liver specific delivery of messenger rna.
Disclosed herein are compositions and methods of modul... |
|
|
Invention
|
Quantitative assessment for cap efficiency of messenger rna.
The present invention provides, amo... |
|
2023
|
Invention
|
Lipid formulations for delivery of messenger rna.
The present invention provides, among other th... |
|
|
Invention
|
Compositions of dry powder formulations of messenger rna and methods of use thereof. The present ... |
|
|
Invention
|
Modification of rna-related enzymes for enhanced production.
The present invention provides, amo... |
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|
Invention
|
Methods and compositions for delivering mrna coded antibodies.
The present invention provides, a... |
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|
Invention
|
Mrna therapy for pompe disease.
The present invention provides, among other things, methods of t... |
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|
Invention
|
"good" buffer-based cationic lipids.
The present invention provides, in part, second generation ... |
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|
Invention
|
Mrna therapeutic compositions and use to treat diseases and disorders.
Disclosed are composition... |
|
2022
|
Invention
|
Large-scale synthesis of messenger rna.
The present invention provides methods for large-scale p... |
|
|
Invention
|
Screening codon-optimized nucleotide sequences.
The present invention relates to methods for scr... |
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|
Invention
|
Assay for quantitative assessment of mrna capping efficiency.
The invention relates to a method ... |
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|
G/S
|
Pharmaceutical preparations; medicines; biological preparations for medical use; biotherapeutics;... |
|
|
Invention
|
Methods for measuring poly a tail length.
The present invention provides, among other things, me... |
|
|
Invention
|
Improved compositions for delivery of mrna.
The present invention provides, among other things, ... |
|
|
Invention
|
"good" buffer-based cationic lipids.
The present invention provides, among other things, a novel... |
|
|
Invention
|
Optimized nucleotide sequences encoding the extracellular domain of human ace2 protein or a porti... |
|
2021
|
Invention
|
Improved process and formulation of lipid nanoparticles.
The present invention provides an impro... |
|
|
Invention
|
Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr.
The present inve... |
|
|
Invention
|
Methods for purification of messenger rna.
The present invention relates, in part, to methods, s... |
|
|
G/S
|
Pharmaceutical preparations for the treatment of rare or orphan diseases, pulmonary disorders, me... |
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|
G/S
|
Pharmaceutical preparations for the treatment of rare autoimmune diseases, pulmonary disorders, m... |
|
|
Invention
|
Tes-based cationic lipids.
The present invention provides, in part, TES-based lipid compounds of... |
|
|
Invention
|
Optimized nucleotide sequences encoding sars-cov-2 antigens.
The present invention relates to op... |
|
|
Invention
|
Improved processes for in vitro transcription of messenger rna.
The present invention provides m... |
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2020
|
Invention
|
Mrna encoding engineered cftr.
The present invention provides, among other things, improved meth... |
|
2017
|
G/S
|
Pharmaceutical preparations; medicines; biological
preparations for medical use; biotherapeutics... |
|
|
G/S
|
medical and scientific research |
