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2024
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Invention
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Lyophilized pharmaceutical compositions comprising a lipid nanoparticle.
Disclosed herein are no... |
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Invention
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Process of preparing mrna-loaded lipid nano particles.
The present invention provides an improve... |
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Invention
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Process of preparing mrna-loaded lipid nanoparticles.
The present invention provides an improved... |
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Invention
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Cns delivery of mrna and uses thereof.
The present invention provides, among other things, metho... |
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Invention
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Composition and methods for treatment of primary ciliary dyskinesia.
The present invention provi... |
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Invention
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Messenger rna therapy for treatment of articular disease.
The present invention provides, among ... |
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Invention
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Ionizable cationic lipids.
Disclosed herein are novel compounds, pharmaceutical compositions com... |
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Invention
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Cationic polymers.
Disclosed are cationic polymers comprising monomers such as those described i... |
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Invention
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Ribose cationic lipids.
Disclosed are cationic lipids which are compounds of Formula (I′).
Dis... |
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Invention
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Processes of preparing mrna-loaded lipid nanoparticles.
The present invention provides an improv... |
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Invention
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Liver specific delivery of messenger rna.
Disclosed herein are compositions and methods of modul... |
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Invention
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Quantitative assessment for cap efficiency of messenger rna.
The present invention provides, amo... |
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2023
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Invention
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Lipid formulations for delivery of messenger rna.
The present invention provides, among other th... |
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Invention
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Compositions of dry powder formulations of messenger rna and methods of use thereof. The present ... |
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Invention
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Modification of rna-related enzymes for enhanced production.
The present invention provides, amo... |
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Invention
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Methods and compositions for delivering mrna coded antibodies.
The present invention provides, a... |
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Invention
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Mrna therapy for pompe disease.
The present invention provides, among other things, methods of t... |
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Invention
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"good" buffer-based cationic lipids. The present invention provides, in part, second generation "... |
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Invention
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Lipid nanoparticle compositions and methods for mrna delivery. Disclosed herein are compositions ... |
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Invention
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Lipid nanoparticle compositions and methods for mrna delivery.
Disclosed herein are compositions... |
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Invention
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Mrna therapeutic compositions and use to treat diseases and disorders.
Disclosed are composition... |
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Invention
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Asymmetric piperazine-based cationic lipids. The present invention provides, in part, asymmetric ... |
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2022
|
Invention
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Large-scale synthesis of messenger rna.
The present invention provides methods for large-scale p... |
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Invention
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Composition and methods for treatment of primary ciliary dyskinesia. The present invention provid... |
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Invention
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Cftr mrna compositions and related methods and uses.
Materials, formulations, production methods... |
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Invention
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Ribonucleic acids with 4'-thio-modified nucleotides and related methods.
Disclosed are messenger... |
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Invention
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Assay for quantitative assessment of mrna capping efficiency.
The invention relates to a method ... |
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P/S
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Pharmaceutical preparations; medicines; biological preparations for medical use; biotherapeutics;... |
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|
Invention
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Methods for measuring poly a tail length.
The present invention provides, among other things, me... |
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Invention
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"good" buffer-based cationic lipids.
The present invention provides, among other things, a novel... |
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2021
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Invention
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Improved process and formulation of lipid nanoparticles.
The present invention provides an impro... |
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Invention
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Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr.
The present inve... |
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Invention
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Methods for purification of messenger rna.
The present invention relates, in part, to methods, s... |
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P/S
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Pharmaceutical preparations for the treatment of rare or orphan diseases, pulmonary disorders, me... |
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Invention
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Piperazine-based cationic lipids.
The present invention provides, in part, piperazine-based lipi... |
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Invention
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Tes-based cationic lipids.
The present invention provides, in part, TES-based lipid compounds of... |
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Invention
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Peg lipidoid compounds.
The compounds disclosed herein (e.g., compounds having a structure accor... |
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Invention
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Optimized nucleotide sequences encoding sars-cov-2 antigens.
The present invention relates to op... |
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Invention
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Generation of optimized nucleotide sequences.
A method for generated an optimized nucleotide seq... |
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Invention
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Improved compositions for cftr mrna therapy.
The present invention provides, among other things,... |
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Invention
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Phenolic acid lipid based cationic lipids.
The present invention provides, in part, phenolic aci... |
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Invention
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Improved processes for in vitro transcription of messenger rna.
The present invention provides m... |
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2020
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Invention
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Mrna encoding engineered cftr.
The present invention provides, among other things, improved meth... |
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Invention
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Improved mrna-loaded lipid nanoparticles and processes of making the same.
The present invention... |
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2019
|
Invention
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Composition and methods for treatment of methylmalonic acidemia.
The present invention provides,... |
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2017
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P/S
|
Pharmaceutical preparations; medicines; biological
preparations for medical use; biotherapeutics... |
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P/S
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medical and scientific research |
