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2024
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Invention
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Novel rna base editing compositions, systems, methods and uses thereof.
The present invention pr... |
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Invention
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Interferon inhibition with viral proteins and fragments and fusions thereof. Provided herein is a... |
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Invention
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Prime editing of single base mutations in sickle cell disease. HBB HBB gene with prime editing. |
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Invention
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Cd5-binding polypeptides, compositions comprising the same, and methods for use thereof. in vivoi... |
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Invention
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Ionizable lipids with branched head groups. The present disclosure describes compositions, prepar... |
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Invention
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Ionizable lipids with linear head groups. The present disclosure describes compositions, preparat... |
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Invention
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Modified immune effector cells with improved resistance to natural killer cell-mediated allorejec... |
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Invention
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Anti-idiotypic antibodies to cluster of differentiation 7-targeted binding domains and related co... |
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Invention
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Nanomaterials.
The present disclosure describes compositions, preparations, nanoparticles (such ... |
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Invention
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Nanomaterials comprising tetravalent lipid compounds.
The present disclosure describes compositi... |
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Invention
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Nanomaterials comprising diamines.
The present disclosure describes compositions, preparations, ... |
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Invention
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Ionizable amine and ester lipids and lipid nanoparticles.
The present disclosure describes compo... |
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Invention
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Ionizable amine lipids and lipid nanoparticles.
The present disclosure describes compositions, p... |
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Invention
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Nanomaterials comprising disulfides.
The present disclosure describes compositions, preparations... |
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Invention
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Methods and compositions for treating alpha-1 antitrypsin deficiency. Compositions and methods fo... |
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Invention
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Compositions and methods for the treatment of spinal muscular atrophy (sma).
The invention of th... |
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Invention
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Crispr enzymes, methods, systems and uses thereof.
The present invention provides novel systems,... |
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Invention
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Modified immune cells and methods of using the same.
The present invention features modified imm... |
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Invention
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Methods and compositions for anti-cd45 based non-genotoxic conditioning. The disclosure compositi... |
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Invention
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Compositions and methods for the treatment of hereditary angioedema (hae).
The invention of the ... |
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Invention
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Compositions and methods for treating stargardt disease. ABCA4ABCA4ABCA4 gene so that the nucleot... |
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Invention
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Modified guide rna. The present invention relates to modified gRNA molecules, compositions and me... |
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Invention
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Genetic modification of hepatocytes.
The present invention provides methods of producing genetic... |
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Invention
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Compositions and methods for treating hepatitis b virus infection.
The invention features compos... |
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Invention
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Immunosuppressant-resistant modified allogeneic modified immune cells and methods for use thereof... |
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Invention
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Nanomaterials comprising triols.
The present disclosure describes compositions, preparations, na... |
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Invention
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Modified immune effector cells with improved efficacy. Multiplex base edited chimeric antigen rec... |
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Invention
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Persistent allogeneic modified immune cells and methods of use thereof.
The present disclosure f... |
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Invention
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Chimeric pseudotyped recombinant rabies virus.
Provided herein are chimeric pseudotyped recombin... |
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Invention
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Chimeric pseudotyped recombinant rabies virus. Provided herein are chimeric pseudotyped recombina... |
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Invention
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Guide rnas for crispr/cas editing systems.
The present invention provides, among other things, a... |
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2023
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Invention
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Circular guide rnas for crispr/cas editing systems.
The present invention provides, among other ... |
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Invention
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Compositions and methods for the self-inactivation of base editors.
The invention features polyn... |
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Invention
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Compositions and methods for editing a transthyretin gene. Compositions for gene modification rel... |
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Invention
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Base editing of transthyretin gene.
Provided herein are compositions for gene modification relat... |
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Invention
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Compositions and methods for treating transthyretin amyloidosis.
The invention features composit... |
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Invention
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Base editing of transthyretin gene. Provided herein are compositions for gene modification relate... |
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Invention
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Adenosine deaminase base editors and methods of using same to modify a nucleobase in a target seq... |
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G/S
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Pharmaceutical and biological preparations based on base editing, base modification, nucleobase e... |
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Invention
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Adenosine deaminase variants and uses thereof.
The invention provides adenosine deaminase varian... |
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Invention
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Synthetic polypeptides and uses thereof. Provided herein are synthetic polypeptides including tra... |
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Invention
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Large serine recombinases, systems and uses thereof. The present invention provides novel serine ... |
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Invention
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One vector system for identification of genome modifying enzymes. The present application relates... |
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Invention
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Uses of adenosine base editors.
The disclosure provides methods and compositions for treating bl... |
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Invention
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Modified allogeneic cells and methods and compositions for the preparation thereof. e.g.e.g., T- ... |
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Invention
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Compositions and methods for treating a congenital eye disease. CEP290CEP290CEP290CEP290CEP290 ge... |
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Invention
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Nanomaterials comprising triols. The present disclosure describes compositions, preparations, nan... |
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Invention
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Nanomaterials comprising an ionizable lipid.
The present disclosure describes compositions, prep... |
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Invention
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Adenosine deaminase base editors and methods for use thereof. Adenosine deaminase base editors, c... |
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Invention
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Compositions and methods for non-genotoxic cell conditioning. Compositions and methods for non-ge... |
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2022
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Invention
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Novel crispr enzymes, methods, systems and uses thereof.
The present invention provides novel sy... |
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2019
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G/S
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Pharmaceutical and biological preparations based on base
correction, base editing, base modifica... |
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G/S
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Scientific and medical research in the fields of base editing, base modification, base repair, nu... |
