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2025
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Invention
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Compositions and methods for editing a transthyretin gene.
Compositions for gene modification re... |
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Invention
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Base editing of transthyretin gene.
Provided herein are compositions for gene modification relat... |
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Invention
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Compositions and methods for cell conditioning. Compositions and methods for non-genotoxic monocl... |
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Invention
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Rna base editing compositions, systems, methods and uses thereof.
The present invention provides... |
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Invention
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Synthetic polypeptides and uses thereof.
Provided herein are synthetic polypeptides including tr... |
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Invention
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Nanomaterials comprising triols.
The present disclosure describes compositions, preparations, na... |
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Invention
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Prime editing of single base mutations in alpha-1 antitrypsin deficiency.
This disclosure provid... |
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Invention
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Prime editing of single base mutations in alpha-1 antitrypsin deficiency. SERPINA1SERPINA1 gene w... |
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Invention
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Large serine recombinases, systems and uses thereof.
The present invention provides novel serine... |
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Invention
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One vector system for identification of genome modifying enzymes.
The present application relate... |
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Invention
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Stable rna compositions with stem loop, and methods thereof. The present invention provides, amon... |
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Invention
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Modified allogeneic cells and methods and compositions for the preparation thereof.
The present ... |
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Invention
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Compositions and methods for treating a congenital eye disease.
The present disclosure features ... |
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Invention
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Compositions and methods for altering a nucleobase in a transthyretin polynucleotide. TTRTTR gene... |
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Invention
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Modified immune cells with increased resistance to allorejection. e.g.e.g., T- or NK-cells) havin... |
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2024
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Invention
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Base editors with modified editing windows. Base editors with modified editing windows, such as b... |
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Invention
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Cd19-binding polypeptides, compositions comprising the same, and methods for use thereof. in vivo... |
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Invention
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Adenosine deaminase base editors and methods for use thereof.
Adenosine deaminase base editors, ... |
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Invention
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Compositions and methods for reducing complement activation.
Compositions and methods for reduci... |
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Invention
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Modified regulatory t cells and methods of using the same.
The disclosure features modified regu... |
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Invention
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Identification of nanoparticles for preferential tissue or cell targeting.
Provided herein inclu... |
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Invention
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Compositions and methods for altering complement activation. Compositions and methods for reducin... |
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Invention
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Hemoglobin g-makassar binding polypeptides and antibodies and methods of using the same.
Describ... |
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Invention
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Novel rna base editing compositions, systems, methods and uses thereof.
The present invention pr... |
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Invention
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Compositions and methods for altering a nucleobase in a lipoprotein(a) polynucleotide. LPALPALPA ... |
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Invention
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Compositions and methods for base editing a phenylalanine hydroxylase polynucleotide. PAHPAHPAH p... |
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Invention
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Methods of substituting pathogenic amino acids using programmable base editor systems.
Provided ... |
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Invention
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Interferon inhibition with viral proteins and fragments and fusions thereof. Provided herein is a... |
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Invention
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Prime editing of single base mutations in sickle cell disease. HBB HBB gene with prime editing. |
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Invention
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Cd5-binding polypeptides, compositions comprising the same, and methods for use thereof. in vivoi... |
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Invention
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Ionizable lipids with branched head groups. The present disclosure describes compositions, prepar... |
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Invention
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Ionizable lipids with linear head groups. The present disclosure describes compositions, preparat... |
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Invention
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Modified immune effector cells with improved resistance to natural killer cell-mediated allorejec... |
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Invention
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Anti-idiotypic antibodies to cluster of differentiation 7-targeted binding domains and related co... |
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Invention
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Nanomaterials.
The present disclosure describes compositions, preparations, nanoparticles (such ... |
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Invention
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Nanomaterials comprising tetravalent lipid compounds.
The present disclosure describes compositi... |
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Invention
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Nanomaterials comprising diamines.
The present disclosure describes compositions, preparations, ... |
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Invention
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Ionizable amine and ester lipids and lipid nanoparticles.
The present disclosure describes compo... |
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Invention
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Ionizable amine lipids and lipid nanoparticles.
The present disclosure describes compositions, p... |
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Invention
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Methods and compositions for treating alpha-1 antitrypsin deficiency. Compositions and methods fo... |
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Invention
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Compositions and methods for the treatment of spinal muscular atrophy (sma).
The invention of th... |
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Invention
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Methods and compositions for anti-cd45 based non-genotoxic conditioning. The disclosure compositi... |
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Invention
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Compositions and methods for the treatment of hereditary angioedema (hae).
The invention of the ... |
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Invention
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Compositions and methods for treating stargardt disease. ABCA4ABCA4ABCA4 gene so that the nucleot... |
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Invention
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Modified guide rna. The present invention relates to modified gRNA molecules, compositions and me... |
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Invention
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Modified immune effector cells with improved efficacy. Multiplex base edited chimeric antigen rec... |
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2023
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Invention
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Circular guide rnas for crispr/cas editing systems.
The present invention provides, among other ... |
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P/S
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Pharmaceutical and biological preparations based on base editing, base modification, nucleobase e... |
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2022
|
Invention
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Compositions and methods for genome editing the neonatal fc receptor.
Provided herein are compos... |
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2021
|
Invention
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Fratricide resistant modified immune cells and methods of using the same.
The present invention ... |
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2019
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P/S
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Pharmaceutical and biological preparations based on base
correction, base editing, base modifica... |
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P/S
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Scientific and medical research in the fields of base editing, base modification, base repair, nu... |
