The present invention relates to a medical device to be applied to a body of a human or animal being. The medical device comprises a contact surface to contact the body of the human or animal being when the medical device is applied to the body of the human or animal being. The contact surface is covered with a soluble surface sealing. The surface sealing is composed of an organic compound.
A61L 2/08 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques des radiations
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
2.
VASCULAR DEVICE AND METHOD FOR MANUFACTURING A VASCULAR DEVICE
A vascular device for insertion in a body lumen, wherein the device includes a surface including at least a portion that is a functionalized surface provided with double or more charged ions such that the ions are exposed to a bodily fluid when the vascular device is inserted in the body lumen. The vascular device allows for reducing complications in its use and, particularly, for improving a desired healing in the body and preventing restenosis. At the same time, it allows for being manufactured at comparably low effort and for a convenient handling.
A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
A61L 33/00 - Traitement antithrombogénique d'articles chirurgicaux, p. ex. de sutures, cathéters, prothèses ou d'articles pour la manipulation ou le conditionnement du sangMatériaux pour un tel traitement
A61L 33/02 - Utilisation de matériaux inorganiques
3.
MEDICAL DEVICE AND PROCESS OF PREPARING A MEDICAL DEVICE
The present invention relates to a medical device to be applied to a body of a human or animal being. The medical device comprises a contact surface to contact the body of the human or animal being when the medical device is applied to the body of the human or animal being. The contact surface is covered with a soluble surface sealing. The surface sealing is composed of an organic compound.
A vascular device (1) for insertion in a body lumen (7) comprises a surface (111), wherein at least a portion of the surface (111) is provided with double or more charged ions (112) such that the ions (112) are exposed to a bodily fluid (71) when the vascular device (1) is inserted in the body lumen (7). The vascular device (1) allows for reducing complications in its use and, particularly, for improving a desired healing in the body and preventing restenosis. At the same time, it allows for being manufactured at comparably low effort and for a convenient handling.
The present invention relates to an implant for insertion in a body lumen, wherein at least a portion of the surface is arranged to contact a wall of the body lumen and/or bodily fluid flowing through the lumen when the implant is inserted in the body lumen. The abovementioned portion of surface is covered with a surface sealing which is designed to dissolve within about 30 seconds when inserting the implant in the body lumen, such that this portion of surface is exposed to the body lumen. The present invention also relates to a method of manufacturing an implant as above described, comprising the steps of obtaining an implant with a surface; providing at least a portion of such surface with target characteristics; and covering such at least a portion of surface with a surface sealing to preserve the target characteristics. The present invention also refers to an implant set comprising an implant as defined and to a use of such an implant for treating an animal or a human body, wherein the treatment procedure comprises dissolving the surface sealing covering at least a portion of a surface of the implant by flushing the surface with a dissolving solution.
The present invention relates to an implant (1) for insertion in a body lumen, wherein at least a portion of the surface (10) is arranged to contact a wall of the body lumen and/or bodily fluid flowing through the lumen when the implant (1) is inserted in the body lumen. The abovementioned portion of surface (10) is covered with a surface sealing (2) which is designed to dissolve within about 30 seconds when inserting the implant (1) in the body lumen, such that this portion of surface (10) is exposed to the body lumen. The present invention also relates to a method of manufacturing an implant (1) as above described, comprising the steps of obtaining an implant (1) with a surface (10); providing at least a portion of such surface (10) with target characteristics; and covering such at least a portion of surface (10) with a surface sealing (2) to preserve the target characteristics. The present invention also refers to an implant set (100) comprising an implant (1) as defined and to a use of such an implant (1) for treating an animal or a human body, wherein the treatment procedure comprises dissolving the surface sealing (2) covering at least a portion of a surface (10) of the implant (1) by flushing the surface (10) with a dissolving solution.
An arrangement for storage of a self-expanding stent-like device (3) includes a container (1) for storing the stent-like device (3) and a stent delivery system arranged at the container (1) and comprising an outer tube (6) and an inner shaft (4) axially moveable relative to the outer tube (6). The container (1) comprises an interior space (2) and one stent passage opening (20; 20'). A distal end (21) of the outer tube (6) is connected to the stent passage opening (20; 20'). An insertion part of ring-like shape is located at the stent passage opening (20; 20'). The inner shaft (4) extends through the insertion part and comprises a retainer (5) for preventing the stent-like device (3) from axial movement relative to the inner shaft (4). When the stent-like device (3) is stored in the interior space (2) of the container, a proximal end of the stent-like device is compressed to a diameter smaller than a diameter of the insertion part and is held radially compressed by the insertion part. The stent-like device (3) is safely stored inside the container (1) and can be prepared for implantation by continuous pulling of the inner shaft (4), which loads the stent-like device (3) into the outer tube (6) and detaches the delivery system from the container (1).
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
A61F 2/01 - Filtres implantables dans les vaisseaux sanguins
An implant for vascular implantation in a body is provided with a surface which, in the implanted state, is provided for contact with the body or with a body fluid and which is at least for the most part hydrated. The surface is advantageously provided as a polished metal surface of a chromium-containing alloy. The vascular implant is used to regulate an adsorption of proteins on the surface of the implant, in respect of the type, quantity and/or shape of defined proteins, by a defined surface which is at least for the most part hydrated.
The invention relates to an implant for implantation into a body. The implant comprises a surface that is provided for contact with the body or a body fluid when implanted and which surface has a first surface charge when in a first state. The surface assumes a second state having a second surface charge as a result of surface treatment, the second surface charge having a lower positive surface charge or a higher negative surface charge than the first surface charge. The implant is used for regulating an adsorption of proteins on the surface of the implant in terms of type, quantity and/or conformation of certain proteins by means of a defined second state of the surface, which has a defined second surface charge and/or a defined predetermined composition of an oxide layer of the surface.
A packaging system comprises packaging for an implant (6) and/or a catheter (7), which has a receptacle (1) for the implant (6) and/or the catheter (7) and has at its distal end a closure (2) and an opening or actuating mechanism with a closable and expandable axial passage (5). An insertion aid for the insertion of a removal device and/or a wire (14) into an inner lumen of the implant and/or catheter is provided by a sleeve-like insertion element (10, 100, 101, 102, 103, 104), which is arranged at least partially within the axial passage (5) in the closure (2), or is formed by the closing element. An opposite, distal end forms an insertion opening (120) for the removal device and/or the wire (14) into the insertion element.
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
11.
ARANGEMENT AND METHOD FOR PREPARING A STENT FOR IMPLANTATION USING A COVER
In a method and an arrangement for preparing an implant for implantation in a lumen in a body, at least one processing unit (1) for processing the implant (7; 103), a cover (2) that has a front opening (3) and a rear opening (4) which is arranged at least in part on or in the processing unit (1), and at least one flow unit (5) are used. The implant (7; 103) can be stored inside the cover (2), between the openings (3, 4) therein. The flow unit (5) is used to generate a flow (P) of a defined medium through the cover (2) and is connected to at least one opening (3; 4) in the cover (2), the flow (P) flowing around the implant (7; 103) within the cover (2).
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes
12.
METHOD AND DEVICE FOR DETERMINING SURFACE CHARACTERISTICS OF STENTS, AND STENT HAVING DEFINED SURFACE CHARACTERISTICS
Disclosed are a method and a device for determining surface characteristics of a stent to be implanted in a lumen in a body, a wetting behavior of a stent surface being used as a measure for the surface characteristics of the stent surface. In order to determine the wetting behavior, a course of a wetting power along a length of the stent surface is determined, a wetting power between the stent surface and a liquid surface being detected along the length of the stent.
G01N 13/02 - Recherche de la tension superficielle des liquides
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61F 2/86 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles
13.
Metal stent for treating lesions in blood vessels, comprising a packaging
The system according to the present disclosure includes a metal stent (3) as a medical implant for treating lesions in blood vessels and a packaging (1) having an inside volume, in which the stent (3) is arranged in a protected manner. The stent (3) has a plurality of webs (33), which produce a tubular shape with each other, and a proximal end (31) and a distal end (32), between which a stent lumen (34) extends. The stent surface (35) has a hydrophilic property. The molecular chemical impurities originating in the atmosphere, primarily hydrocarbon compounds, are significantly reduced on the surface by a treatment, whereby the contact angle as a measure of the hydrophilicity of a water drop present on the surface (35) is reduced in proportion to the contact angle prior to said treatment. The stent (3) is stored in an inert manner in the packaging (1).
B65D 85/00 - Réceptacles, éléments d'emballage ou paquets spécialement adaptés à des objets ou à des matériaux particuliers
A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles
A61B 19/02 - Boîtiers ou étuis protecteurs pour appareils ou pour instruments, p.ex. boîtes ou étuis stériles; Tables ou armoires pour instruments; Sacs de docteur
14.
Device and method for providing a stent for implantation
A device and a method for providing a stent for implantation into a body lumen are provided, wherein the stent (3) has a proximal end (31) and a distal end (32), between which a stent lumen having a compressible diameter d extends. The device comprises a crimping apparatus (4), having elements (40) which are disposed about an axis and can be moved at least partially relative to each other radially to the axis, and an activator (42) for actuating the crimping apparatus (4). The elements (40) of the crimping apparatus comprise the stent (3) and can be moved radially by means of the activator (42) from a widened position, in which the stent (3) is not crimped, into a closed position, in which the diameter d of the stent (3) is compressed. According to the invention, a storage compartment comprising an inert medium or an inert filling is provided, which forms a jacket in which the stent (3) is stored in an inert manner at least the majority of the time, while the elements (40) enclose the stent (3) and are moved from the widened position into the closed position. The inert jacket can be interrupted during compression of the stent.
B21D 41/00 - Utilisation de procédés permettant de modifier le diamètre des extrémités des tubes
A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
15.
DEVICE AND METHOD FOR PROVIDING A STENT FOR IMPLANTATION
A device and a method for providing a stent for implantation into a body lumen are provided, wherein the stent (3) has a proximal end (31) and a distal end (32), between which a stent lumen having a compressible diameter d extends. The device comprises a crimping apparatus (4), having elements (40) which are disposed about an axis and can be moved at least partially relative to each other radially to the axis, and an activator (42) for actuating the crimping apparatus (4). The elements (40) of the crimping apparatus comprise the stent (3) and can be moved radially by means of the activator (42) from a widened position, in which the stent (3) is not crimped, into a closed position, in which the diameter d of the stent (3) is compressed. According to the invention, a storage compartment comprising an inert medium or an inert filling is provided, which forms a jacket in which the stent (3) is stored in an inert manner at least the majority of the time, while the elements (40) enclose the stent (3) and are moved from the widened position into the closed position. The inert jacket can be interrupted during compression of the stent.
The system according to the invention comprises a metal stent (3) as a medical implant for treating lesions in blood vessels and a packaging (1) having an inside volume, in which the stent (3) is arranged in a protected manner. The stent (3) has a plurality of webs (33), which produce a tubular shape with each other, and a proximal end (31) and a distal end (32), between which a stent lumen (34) extends. The stent surface (35) has a hydrophilic property. The molecular chemical impurities originating in the atmosphere, primarily hydrocarbon compounds, are significantly reduced on the surface by a treatment, whereby the contact angle as a measure of the hydrophilicity of a water drop present on the surface (35) is reduced in proportion to the contact angle prior to said treatment. The stent (3) is stored in an inert manner in the packaging (1).
brevets
