Abrégé

The present invention relates to a method for assisting the diagnosis of secondary progressive multiple sclerosis, the method including: a step in which the relative abundance of Tyzzerella nexilis in a fecal sample collected from a subject is measured; and a step in which, when the relative abundance of Tyzzerella nexilis is larger than that in a fecal sample collected from a normal person, it is determined that the subject has been affected with or is potentially affected with secondary progressive multiple sclerosis. The Tyzzerella nexilis is a bacterium that carries genome DNA having a 97% or higher average nucleotide identity with the nucleotide sequence for the genome DNA represented by SEQ ID NO: 1.

Classes IPC  ?

• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
• A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• C12N 1/20 - BactériesLeurs milieux de culture
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• C12Q 1/686 - Réaction en chaine par polymérase [PCR]
• C12Q 1/6851 - Amplification quantitative
• C12Q 1/6869 - Méthodes de séquençage

Abrégé

The present invention provides a system for quantifying the effects of a change of a condition pertaining to a subject for a prescribed period, wherein the change, which occurs for the prescribed period, includes at least a change from a first condition to a second condition. The system comprises: a reception means which receives data measured from the subject, the data including first data measured from the subject in the first condition and second data measured from the subject in the second condition; a derivation means which derives, from the received data, at least a first component that represents an accumulation of a load on the subject for the prescribed period and a second component that varies following the change; and an output means which outputs at least one of the derived first component and second component.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne

Abrégé

The present invention provides a translucent magnetic material having excellent optical characteristics. The translucent magnetic material comprises a plurality of magnetic particles which include a plurality of FeCo particles, and a translucent material in which the plurality of magnetic particles are dispersed. The translucent material includes a ceramic material which contains a compound of fluorine and at least one element from among group III, group IV and group V, and a metal material which is disposed in a region between the plurality of FeCo particles and the ceramic material.

Classes IPC  ?

• G02F 1/09 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des éléments magnéto-optiques, p. ex. produisant un effet Faraday
• C23C 14/14 - Matériau métallique, bore ou silicium
• C23C 14/34 - Pulvérisation cathodique
• G02B 5/00 - Éléments optiques autres que les lentilles
• G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
• H01F 1/00 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriésEmploi de matériaux spécifiés pour leurs propriétés magnétiques
• H01F 1/20 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriésEmploi de matériaux spécifiés pour leurs propriétés magnétiques en matériaux inorganiques caractérisés par leur coercivité en matériaux magnétiques doux métaux ou alliages sous forme de particules, p. ex. de poudre
• H01F 10/16 - Métaux ou alliages contenant du cobalt
• H01F 41/18 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour appliquer des pellicules magnétiques sur des substrats par pulvérisation cathodique

Abrégé

The culture insert container has a lower culture container having a bottom portion equipped with a porous membrane and a sidewall, and having an upper insertion fixture having a cylindrical sidewall that is inserted into said lower culture container. The cylindrical sidewall has a land arranged so as to protrude from a top end of the sidewall of the lower culture container at a location such as will cause a top surface of said porous membrane and a bottom end portion of the cylindrical sidewall which is inserted within the lower culture container to be maintained in a noncontacting state. A land is arranged at an outer surface of the cylindrical sidewall so as to cause a constant distance to be maintained between an inner surface of the sidewall of the lower culture container and the outer surface of the cylindrical sidewall.

Classes IPC  ?

• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains

Abrégé

An atom beam generation device includes an atomic oven including a reservoir in which a sample is contained, a deceleration unit, and coil units. The deceleration unit includes a bore through which an atomic beam and a slowing laser beam pass, and decelerates an atomic beam emitted from the atomic oven by means of slowing laser beam and a magnetic field. The coil units supply Joule heat to the atomic oven, and generate a magnetic field in the deceleration unit.

Classes IPC  ?

• H05H 3/02 - Production d'un faisceau moléculaire ou atomique, p. ex. d'un faisceau résonnant
• G04F 5/14 - Appareils pour la production d'intervalles de temps prédéterminés, utilisés comme étalons utilisant des horloges atomiques

Abrégé

A learning method includes: causing an observer to perceive information to be compared by the observer from among a plurality of pieces of perceivable information; acquiring evaluation for the information made by the observer; and rating the plurality of pieces of information based on the evaluation made by the observer for the plurality of pieces of information acquired by a plurality of repetitions of the causing the observer to perceive the information and the acquiring the evaluation.

Classes IPC  ?

• G06T 7/00 - Analyse d'image

Abrégé

An object of the present invention is to provide a method capable of detecting activity of an enzyme that strictly recognizes a substrate, such as acetylcholinesterase (AChE). There is provided a method for detecting activity of an enzyme in a biological sample using a microdevice, the method including a step of bringing the biological sample into contact with a substrate analog or a natural substrate, and a compound represented by General Formula (I) below or a salt thereof, wherein the substrate analog or the natural substrate generates a compound A having a thiol group (R—SH), a selenol group (R—SeH), or a poly sulfur atom (R—(S)n-H) (R is a hydrogen atom or an alkyl group, and n is 1 to 5) by a reaction with the enzyme, and fluorescence is observed or measured, the fluorescence being emitted or enhanced from a fluorescent product generated by the reaction of the compound represented by General Formula (I) or the salt thereof with the thiol group, the selenol group, or the poly sulfur atom.

Classes IPC  ?

• G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
• C07F 5/02 - Composés du bore
• C07F 7/08 - Composés comportant une ou plusieurs liaisons C—Si
• C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
• C12Q 1/46 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une estérase une cholinestérase

Abrégé

For the purpose of improving the luminous efficiency of a light emitting element by increasing conduction characteristics, a light emitting element 100 according to an embodiment of the present disclosure includes an AlGaN-based crystal or an InAlGaN-based crystal, and is provided with a light emitting layer 134, at least one electron blocking layer 138, a first Mg-doped layer 140, and a dam layer 150, which are sequentially stacked in this order in the direction of the flow of electrons. The dam layer 150 has a higher Al composition ratio than the first Mg-doped layer. Another embodiment of the present disclosure provides a method for manufacturing a light emitting element that is provided with an Mg-doped layer of any one of a GaN-based crystal, InGaN-based crystal, AlGaN-based crystal, and InAlGaN-based crystal, the method including an activation step for causing an electron catalytic reaction in a first Mg-doped layer so as to activate Mg into an ionized acceptor.

Classes IPC  ?

• H10H 20/825 - Matériaux des régions électroluminescentes comprenant uniquement des matériaux du groupe III-V, p. ex. GaP contenant de l’azote, p. ex. GaN
• H10H 20/83 - Électrodes
• H10H 20/816 - Corps ayant des structures contrôlant le transport des charges, p. ex. couches semi-conductrices fortement dopées ou structures bloquant le courant

Abrégé

The present invention enhances light extraction efficiency (LEE) in a 230 nm band UVC-LED. This AlGaN-based deep ultraviolet LED having a light emission wavelength λ has a photonic crystal periodic structure in a thickness direction, wherein the distance between an upper part of a quantum well layer and a bottom part of the photonic crystal periodic structure substantially satisfies a resonance condition λ/n of free end reflection. Here, n is the weighted average refractive index of a layer structure existing between the upper part of the quantum well layer and the bottom part of the photonic crystal periodic structure.

Classes IPC  ?

• H01L 33/10 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure réfléchissante, p.ex. réflecteur de Bragg en semi-conducteur
• H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote

Abrégé

The present invention addresses the problem of elucidating the function of human Mhr1 and providing a method for improving mitochondrial function. Provided is a method for promoting mitochondrial DNA homoplasmy formation or for improving mitochondrial function, the method including introducing a protein having 80% or higher sequence identity with the amino acid sequence represented by SEQ ID NO: 1 or DNA or mRNA encoding a protein having 80% or higher sequence identity with the amino acid sequence represented by SEQ ID NO: 1 into a cell.

Classes IPC  ?

• C12N 15/12 - Gènes codant pour des protéines animales
• A23L 33/18 - PeptidesHydrolysats de protéines
• A61K 38/43 - EnzymesProenzymesLeurs dérivés
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus

Abrégé

A superconducting coil device includes a superconducting coil and adhesive layer. The superconducting coil includes a superconducting wire wound into a coil shape. An electrical conductivity is imparted to the adhesive layer. The adhesive layer constitutes at least a part of a current bypass for the superconducting coil. The adhesive layer includes a binder. The adhesive layer includes a resistance-decrease suppression structure that imparts the electrical conductivity to the adhesive layer while suppressing a decrease in contact resistance with the superconducting wire.

Classes IPC  ?

• H01F 6/02 - Étouffement de la supraconductivitéDispositions pour la protection lors de la phase de transition vers l'état de conductivité normale
• H01F 6/06 - Bobines, p. ex. dispositions pour l'enroulement, l'isolation, les enveloppes ou les bornes des bobines

Abrégé

An objective of the present invention is to provide at least one among: an electrode containing a manganese oxide which suppresses the elution of manganese during water electrolysis without reducing hydrogen productivity; and a method for manufacturing the electrode.　The electrode includes a conductive substrate, and an oxygen generating electrode catalyst containing iridium-manganese oxide. The content of iridium per geometric area of the conductive substrate is less than 10 μg/cm2.

Classes IPC  ?

• C25B 11/093 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un métal noble ou oxyde de métal noble et au moins un oxyde d’un métal non noble
• C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
• C25B 9/00 - Cellules ou assemblages de cellulesÉléments de structure des cellulesAssemblages d'éléments de structure, p. ex. assemblages d'électrode-diaphragmeCaractéristiques des cellules relatives aux procédés
• C25B 9/23 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes comprenant des membranes échangeuses d'ions dans ou sur lesquelles est incrusté du matériau pour électrode
• C25B 11/031 - Électrodes poreuses
• C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
• C25B 11/063 - Métal valve, c.-à-d. dont l’oxyde est semi-conducteur, p. ex. titane

Abrégé

Provided is a device for estimating the atomic structure of a biomolecule, the device comprising: a generation unit that generates an image generated on the basis of a target biomolecule; an acquisition unit that acquires a plurality of first candidate structure images on the basis of two-dimensional projection images from a plurality of atomic structures prepared; a global search unit that, on the basis of the similarity between the generated image and the candidate structure images, selects, as a basic candidate structure, a structure having a high degree of structural similarity and/or molecular orientation similarity to the target biomolecule from among the plurality of atomic structure candidate structures; and a local search unit that acquires a plurality of second candidate structure images on the basis of two-dimensional projection images of a plurality of modified atomic structures obtained by modifying the basic candidate structure, and selects, on the basis of the similarity between the second candidate structure images and the generated image, a structure having a high degree of structural similarity and/or molecular orientation similarity to the target biomolecule from among the modified atomic structures.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• G16C 10/00 - Chimie théorique computationnelle, c.-à-d. TIC spécialement adaptées aux aspects théoriques de la chimie quantique, de la mécanique moléculaire, de la dynamique moléculaire ou similaires
• G16C 20/40 - Recherche de structures chimiques ou de données physicochimiques

Abrégé

This inspecting device is a device for inspecting an inner circumferential surface of an object under inspection that has a cylindrical shape. The device comprises: an inspecting unit for emitting terahertz waves toward the inner circumferential surface and detecting reflected waves of the terahertz waves; and a distance measuring unit for measuring the distance between the inspecting unit and the inner circumferential surface. The inspection target and the distance measuring unit are caused to rotate in the circumferential direction of the object under inspection. Further, the relative axial position of the inspecting unit with respect to the object under inspection is adjusted. Further, the position of the inspecting unit in a plane intersecting the axial direction of the object under inspection can be adjusted. Control of the position adjustment mechanism is performed on the basis of the measurement result from the distance measuring unit such that the center of rotation of a rotation unit is positioned on the central axis of the object under inspection.

Classes IPC  ?

• G01B 15/04 - Dispositions pour la mesure caractérisées par l'utilisation d'ondes électromagnétiques ou de radiations de particules, p. ex. par l'utilisation de micro-ondes, de rayons X, de rayons gamma ou d'électrons pour mesurer des contours ou des courbes

Abrégé

A filter circuit 1 comprises: a readout resonator 11 that is coupled to data quantum bits; and a filter resonator 12 that is configured and is coupled to an observation line. The readout resonator 11 and the filter resonator 12 are electrically and magnetically coupled by using capacitive coupling and inductive coupling in parallel.

Classes IPC  ?

• G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit
• G06N 10/70 - Correction, détection ou prévention d’erreur quantique, p. ex. codes de surface ou distillation d’état magique
• H10N 60/00 - Dispositifs supraconducteurs

Abrégé

Provided is an electrode exhibiting high oxygen generating electrode catalytic activity as compared with conventional electrodes using manganese-based oxide as an oxygen generating electrode catalyst.

Classes IPC  ?

• C25B 11/093 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un métal noble ou oxyde de métal noble et au moins un oxyde d’un métal non noble
• B01J 23/34 - Manganèse
• B01J 23/656 - Manganèse, technétium ou rhénium
• C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
• C25B 9/00 - Cellules ou assemblages de cellulesÉléments de structure des cellulesAssemblages d'éléments de structure, p. ex. assemblages d'électrode-diaphragmeCaractéristiques des cellules relatives aux procédés
• C25B 11/042 - Électrodes à base d’un seul matériau
• C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
• C25B 11/079 - Dioxyde de manganèseDioxyde de plomb
• C25B 11/081 - Métal noble

Abrégé

A tissue transplantation resin tip and the like that allow easy transplantation of a tissue sucked inside are provided. A tissue transplantation resin tip 10 according to the present invention includes a needle tube 1 that can be inserted into an eyeball. The needle tube includes a main body portion 11 that extends linearly, and a front end portion 12 that is bent with respect to the main body portion and extends linearly, and that discharges a tissue T from a front end 121. A length L1 of the needle tube is 25 mm or more and 50 mm or less, a cross-sectional external shape of the front end portion has an oval shape having a major axis D1 of 0.8 mm or more and 1.5 mm or less, and a minor axis D2 of 0.5 mm or more and 1.0 mm or less, the front end of the front end portion is a bevel surface that extends in a direction substantially perpendicular to the main body portion, and that has a bevel angle 1 of 50 or more and 85 or less, the hardness of the front end portion is 0.15 N or more and 0.30 N or less, and the hardness of the center of the needle tube is 0.80 N or more and 1.50 N or less.

Classes IPC  ?

• A61F 2/14 - Parties d'yeux, p. ex. cristallins ou implants de cornéeYeux artificiels
• A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil

Abrégé

(1) The purpose of the present invention is to provide an antitumor agent in which an effect of an immune checkpoint inhibitor is enhanced. (2) The purpose of the present invention is also to provide a drug that could exhibit an effect even under conditions in which no antigen is present.　(1) Provided is an antitumor agent obtained by combining an immune checkpoint inhibitor with an NKT cell ligand-containing liposome composition. (2) Also provided is a liposome composition containing an NKT cell ligand and an antigen.

Classes IPC  ?

• A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
• A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
• A61K 31/7032 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un polyol, c.-à-d. composés ayant plusieurs groupes hydroxyle, libres ou estérifiés, y compris le groupe hydroxyle impliqué dans la liaison glycosidique, p. ex. monoglucosyl-diacylglycérides, acide lactobionique, gangliosides
• A61P 35/00 - Agents anticancéreux
• A61P 35/04 - Agents anticancéreux spécifiques pour le traitement des métastases
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• C07H 15/04 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide

Abrégé

In order to achieve a charged particle beam sensor capable of measuring beam position with high linearity, provided is a charged particle beam sensor comprising a plurality of electrodes 1-8 that cover a right cylinder side surface. The plurality of electrodes are insulated from each other by a plurality of separation curves which each draw, with respect to a direction along the axis of the right cylinder side surface, a curve from the minimum value to the maximum value of a sine wave relating to a rotation angle in any rotation direction around the axis of the right cylinder side surface. The charged particle beam is disposed so as to pass through the inside of the right cylinder side surface. In a measurement data processing method, a signal wave second-order integral value is calculated.

Classes IPC  ?

• G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations

Abrégé

The present invention provides a method for acquiring the value of an autonomic nervous system index for evaluating the mental state of a subject. The method comprises acquiring the value of the autonomic nervous system index of the subject at a first time point and a second time point. The autonomic nervous system index or a calculated value thereof serves as an index of the mental state of the subject. The method is characterized in that the sleep state of the subject at the first time differs from at the second time point. The present invention also provides a method, for example, for evaluating the mental state of a subject on the basis of an acquired value of an autonomic nervous system index or a calculated value thereof.

Classes IPC  ?

• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction

Abrégé

The purpose of the present invention is to provide a novel HVEM-binding protein. The present invention provides a human HVEM-binding protein comprising at least one immunoglobulin single variable region, wherein: the immunoglobulin single variable region includes complementarity determining regions 1-3 which have the amino acid sequence of SEQ ID NO: 1, the amino acid sequence of SEQ ID NO: 2, and the amino acid sequence of SEQ ID NO: 3, respectively; and the immunoglobulin single variable region is a humanized VHH. The protein according to the present invention may further comprise a human immunoglobulin Fc region or a human serum albumin-binding protein, and the immunoglobulin Fc region may be an Fc region of human IgG4.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
• A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
• A61P 35/00 - Agents anticancéreux
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• C07K 16/46 - Immunoglobulines hybrides
• C12N 15/13 - Immunoglobulines
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression

Abrégé

A film deposition method including installing a substrate on a turntable of a spin coating device such that a first main surface faces the turntable, and adding a first liquid having viscosity dropwise onto a second main surface of the substrate; holding the substrate in the same state until the first liquid added dropwise reaches the first main surface side from the second main surface side through a through-hole; otating the substrate together with the turntable; and heating the first liquid together with the substrate.

Classes IPC  ?

• G03F 7/16 - Procédés de couchageAppareillages à cet effet
• G03F 7/004 - Matériaux photosensibles
• G03F 7/039 - Composés macromoléculaires photodégradables, p. ex. réserves positives sensibles aux électrons
• G03F 7/09 - Matériaux photosensibles caractérisés par des détails de structure, p. ex. supports, couches auxiliaires
• H10N 60/01 - Fabrication ou traitement

Abrégé

A method of producing radionuclides includes installation, irradiation, transport, and trapping steps. In the installation step, a target material containing a target nuclide is placed inside a target chamber. In the irradiation step, at least a portion of the target material is irradiated with a quantum beam. In the transport stage, a carrier gas is supplied to the inside of the target chamber and an ambient gas around the target material is sent to the outside of the target chamber through an exhaust pipe. In the trapping step, a trap device connected to the exhaust pipe is configured to trap the radionuclides produced from the target nuclide from the ambient gas. In some cases, a target holding device for quantum beam irradiation comprising a target material container and a rotational drive mechanism is also provided, as well as a quantum beam irradiation system. An example target material container is rotatable.

Classes IPC  ?

• G21G 1/04 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p. ex. production d'isotopes radioactifs à l'extérieur des réacteurs nucléaires ou des accélérateurs de particules
• G21G 1/00 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p. ex. production d'isotopes radioactifs
• G21K 5/08 - Supports pour cibles ou pour objets à irradier

Abrégé

The present invention provides a plant root system morphology control means which is effective and easy to use.　The present invention provides a plant root system morphology control agent comprising 2-aminopimelic acid or a salt or ester thereof.

Classes IPC  ?

• A01N 37/44 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou un de leurs dérivés, et un atome d'azote lié au même squelette carboné par une liaison simple ou double, cet atome d'azote ne faisant pas partie d'un dérivé ou d'un thio-analogue d'un groupe carboxylique, p. ex. acides aminocarboxyliques
• A01G 7/06 - Traitement des arbres ou des plantes en cours de croissance, p. ex. pour prévenir la décomposition du bois, pour teinter les fleurs ou le bois, pour prolonger la vie des plantes
• A01H 3/04 - Procédés de modification des phénotypes par traitement au moyen de produits chimiques
• A01P 21/00 - Régulateurs de croissance des végétaux

Abrégé

A data integration apparatus according to one embodiment includes a controller including a platform for automatically performing a type conversion of an object, an acquisition unit, an interpreter, and an integrator. The acquisition unit acquires each data as a graph in which an object of the platform is a constituent element, or as a collection of information in a language format in which an object is associated with a word. The interpreter performs an interpretation process for converting the constituent element of the graph into a type on a hyponymy-side. The integrator performs an integration process for holding information generated by the interpretation process and information acquired by the acquisition unit, and reflecting the information on the graph. The data integration apparatus operates when the controller repeatedly and automatically performs the interpretation process and the integration process.

Classes IPC  ?

• G06F 30/12 - CAO géométrique caractérisée par des moyens d’entrée spécialement adaptés à la CAO, p. ex. interfaces utilisateur graphiques [UIG] spécialement adaptées à la CAO
• G06F 30/13 - Conception architecturale, p. ex. conception architecturale assistée par ordinateur [CAAO] relative à la conception de bâtiments, de ponts, de paysages, d’usines ou de routes
• G06F 40/56 - Génération de langage naturel

Abrégé

Provided is an LED having a quantum well structure and comprising: a quantum well layer having a composition AlaGa1-aN (aluminum gallium nitride) (0 < a < 1); and a high-level layer that has a composition AlbGa1-bN (a < b ≤ 1), is adjacent to the quantum well layer, and has an energy level higher than that of the quantum well layer. ΔX, which is the difference between a and b, and the width D [nm] of the quantum well layer satisfy [relational expression 1] D = k/ΔX (where, in the relational expression 1, D > 3, 0 < ΔX < 0.15, and 0.45 ≤ k ≤ 1.25 (unit of the coefficient k is [nm])).

Classes IPC  ?

• H01L 33/06 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure à effet quantique ou un superréseau, p.ex. jonction tunnel au sein de la région électroluminescente, p.ex. structure de confinement quantique ou barrière tunnel
• H01L 33/14 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure contrôlant le transport des charges, p.ex. couche semi-conductrice fortement dopée ou structure bloquant le courant
• H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote
• H01S 5/343 - Structure ou forme de la région activeMatériaux pour la région active comprenant des structures à puits quantiques ou à superréseaux, p. ex. lasers à puits quantique unique [SQW], lasers à plusieurs puits quantiques [MQW] ou lasers à hétérostructure de confinement séparée ayant un indice progressif [GRINSCH] dans des composés AIIIBV, p. ex. laser AlGaAs

Abrégé

The present invention pertains to: a guide RNA having, on the 5' side of a spacer sequence, a repeat sequence that is cleaved through processing for forming a cascade complex, and not having a repeat sequence or having a sequence that is not cleaved through processing for forming a cascade complex, on the 3' side of the spacer sequence; and a type-I CRISPR-Cas system using the guide RNA.

Classes IPC  ?

• C12N 15/09 - Technologie d'ADN recombinant
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression

Abrégé

A sample preparation system (100) includes a position identification section (34) that associates a plurality of cells constituting a cell group with the respective plurality of cells constituting the cell group in which at least a part of junctions between adjacent ones of the plurality of cells is disconnected, in a dispersion process of (i) disconnecting at least the part of the junctions between the adjacent ones of the plurality of cells in the cell group in which the plurality of cells are joined to each other and (ii) dispersing the cell group. This allows the realization of a technique of collecting a cell and specifying the position of the collected cell in an original cell group.

Classes IPC  ?

• G01N 1/28 - Préparation d'échantillons pour l'analyse

Abrégé

An observation device includes a neutron emission device, a detection device, and a data processing device. The neutron emission device emits neutrons to an inspection object. The detection device detects exit neutrons from the inspection object at one set of detection positions in a peripheral direction around the inspection object, outside the inspection object, and measures the number of the detected exit neutrons for each of the detection positions. The data processing device generates reconstructed cross-sectional data by performing reconstruction processing based on the number of the detected exit neutrons at each of the one set of detection positions. The reconstructed cross-sectional data represent a two-dimensional distribution of a neutron reaction rate in an imaginary cross-section of the inspection object.

Classes IPC  ?

• G01N 23/05 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et formant des images des matériaux en utilisant des neutrons

Abrégé

The present disclosure provides a method for manufacturing a cell aggregate comprising retinal tissue having a layer structure.

Classes IPC  ?

• C12N 5/0793 - Neurones
• C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet

Abrégé

Provided is a quantum computer, including: an input unit for inputting an electron wave packet; a propagation unit that propagates the electron wave packet in a predetermined direction and has a loop-like loop path; and a qubit generation unit that generates a time-bin qubit by using the electron wave packet.

Classes IPC  ?

• G06N 10/20 - Modèles d’informatique quantique, p. ex. circuits quantiques ou ordinateurs quantiques universels
• G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit

Abrégé

Provided is a method for efficiently preparing a library. The method for preparing a library includes the steps of (a) synthesizing single-stranded cDNA from 10 pg or more of template RNA; (b) synthesizing double-stranded cDNA from the single-stranded cDNA; and (c) preparing a library using the double-stranded cDNA that is unpurified.

Classes IPC  ?

• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN

Abrégé

This information processing device is provided with a state information acquisition unit and an analysis processing unit. The state information acquisition unit continuously acquires objective state information of a patient suffering from a disease, and subjective state information based on the patient's subjectivity. On the basis of the objective state information and the subjective state information, and using a predetermined information processing technique, the analysis processing unit continuously executes predetermined analysis processing including setting of a policy recommended to be executed by the patient in order to improve the symptom of the disease, and outputs the result of the analysis processing in a manner that can be perceived by the patient.

Classes IPC  ?

• G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p. ex. la physiothérapie, l’acupression ou les exercices
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux

Abrégé

Provided is an estimation device comprising a control unit that executes an estimation process for estimating dynamic information, which is information relating to the behavior of platelets, on the basis of video data from a video showing the flow of platelets in the blood. In the estimation process, the control unit executes a correlation acquisition process for, on the basis of the video data, acquiring information indicating a correlation among frames, from among a plurality of frames included in the video, satisfying the condition that a difference in time indicated by a time code is smaller than a preset time difference, and estimates the dynamic information on the basis of the result of the correlation acquisition process.

Classes IPC  ?

• G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
• G01N 33/483 - Analyse physique de matériau biologique
• G06T 7/00 - Analyse d'image
• G06T 7/11 - Découpage basé sur les zones
• G06V 10/62 - Extraction de caractéristiques d’images ou de vidéos relative à une dimension temporelle, p. ex. extraction de caractéristiques axées sur le tempsSuivi de modèle

Abrégé

A composition for decomposition of trypsin or TMPRSS2 containing, as an active ingredient, bacteria that have 00502 protein, or a protein having 30% or higher sequence identity with an amino acid sequence of the 00502 protein and having a trypsin-binding ability; or bacteria that have 00509 protein, or a protein having 30% or higher sequence identity with an amino acid sequence of the 00509 protein and having a trypsin-binding ability.

Classes IPC  ?

• A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 31/04 - Agents antibactériens
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

The preventive or therapeutic agent for benign adult familial myoclonus epilepsy (BAFME) of the present invention contains an antisense oligonucleotide containing at least one of the base sequences of SEQ ID NOS: 1 to 4. Among the antisense oligonucleotides, oligonucleotide consisting of at least one of the base sequences of SEQ ID NOS: 1 to 4 may contain at least one RNase H inactive type nucleotide analog. The RNase H inactive type nucleotide analog may be β-D-oxy-L-LNA, β-D-ENA, R type cEt, 2′-OMe-nucleotide analog, and/or MOE-nucleotide analog.

Classes IPC  ?

• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
• A61P 25/08 - AntiépileptiquesAnticonvulsivants

Abrégé

Provided are: a composition for ammonia storage and an ammonia bonding composition, with which ammonia can be stored relatively easily under mild conditions and can be stored with high safety; and an ammonia storage device and an ammonia storage method, which use same. The composition for ammonia storage contains a compound for ammonia storage which is represented by any of specific formulae (I-a) to (I-c). In addition, the ammonia bonding composition contains said composition for ammonia storage and is obtained by bonding the compound to an ammonia molecule and a water molecule. In addition, the ammonia storage device, the ammonia storage method and an ammonia molecule removal method use the foregoing.

Classes IPC  ?

• C01C 1/02 - Préparation ou séparation d'ammoniac
• C01G 21/16 - Halogénures

Abrégé

The present invention relates to a method for conducting phylogenetic analysis of cells. The method of the present invention includes steps of: (1) comparing, for a plurality of single cells derived from the same individual, the RNA sequence data of the transcriptome of each single cell with the corresponding genome sequence data, and then screening for a site where the RNA sequence differs from the genome sequence; (2) screening the sites identified by screening in step (1) for a site where three or more single nucleotide polymorphisms are detected, as a site of somatic mutation; and (3) generating a cell lineage tree based on the nucleotide sequence information of the site of somatic mutation obtained in step (2).

Classes IPC  ?

• G16B 20/00 - TIC spécialement adaptées à la génomique ou protéomique fonctionnelle, p. ex. corrélations génotype-phénotype
• G16B 25/10 - Profilage de l’expression de gènes ou de protéinesEstimation ou normalisation de ratio d’expression
• G16B 45/00 - TIC spécialement adaptées à la visualisation de données liées à la bio-informatique, p. ex. affichage de cartes ou de réseaux

Abrégé

Provided is a technique for examining an autoimmune disease. This method for examining an autoimmune disease involves (1) a step for examining the presence or absence of endogenous human herpesvirus 6B in genomic DNA of a biological sample sampled from a subject.

Classes IPC  ?

• C12Q 1/6869 - Méthodes de séquençage
• C12N 15/09 - Technologie d'ADN recombinant

Abrégé

Provided is a novel drug for tumor therapy which targets an S1P signaling pathway. A tumor therapeutic agent according to one embodiment of the present invention which comprises a complex that includes an acrolein reaction site having a chemical structure represented by formula (1), and a detachment site, wherein the detachment site is bonded to the acrolein reaction site via a linker that can be cleaved by a reaction between the acrolein reaction site and acrolein, and the detachment site includes a chemical structure of a compound which exhibits an activity for inhibiting sphingosine-1-phosphate signal transduction in a cell.

Classes IPC  ?

• A61K 31/27 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carbamiques ou thiocarbamiques, p. ex. méprobamate, carbachol, néostigmine
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention aims to provide a method for suppressing differentiation of ganglion cell, amacrine cell, horizontal cell and/or bipolar cell in a neural retina tissue containing photoreceptor precursor and/or photoreceptor, and the like. A method for suppressing differentiation of a ganglion cell, an amacrine cell, a horizontal cell and/or a bipolar cell in a neural retinal tissue containing a photoreceptor precursor and/or a photoreceptor, including a step of culturing a retinal tissue comprising a neural retinal progenitor cell and in any stage between a differentiation stage immediately after emergence of a ganglion cell and a differentiation stage where emergence rate of a cone photoreceptor precursor reaches maximum in a medium containing a thyroid gland hormone signal transduction pathway agonist.

Classes IPC  ?

• A61L 27/38 - Cellules animales
• C12N 5/0793 - Neurones
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

A quality monitoring apparatus (10) is provided with a quality measurement device (30) that irradiates a food (1) with an electromagnetic wave, and measures an index value indicating the quality state of the food (1) on the basis of the response of the food (1) to the irradiation. The quality measurement device (30) is provided with a Raman scattered light measurement device (30A) that irradiates a food with laser light as an electromagnetic wave, and measures, as an index value, a value related to the intensity of Raman scattered light generated from the food 1 with respect to the laser light. Alternatively, the quality measurement device (30) is provided with a terahertz wave measurement device (30B) that irradiates the food (1) with a terahertz wave as an electromagnetic wave, and measures, as an index value, a value related to the absorption rate of the terahertz wave in the food (1).

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman
• A23L 5/30 - Traitement physique, p. ex. par des moyens électriques ou magnétiques, par énergie ondulatoire ou par irradiation
• F24C 7/04 - Poêles ou fourneaux chauffés à l’électricité dans lesquels la chaleur est rayonnée directement par l'élément chauffant
• G01N 21/3586 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge en utilisant la lumière de l'infrarouge lointainCouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge en utilisant un rayonnement térahertz par spectroscopie térahertz dans le domaine temporel [THz-TDS]

Abrégé

A method for producing matured cardiomyocytes, the method comprising: a preparation step for preparing a sample containing immature cardiomyocytes; and a pressure loading step for continuously or intermittently applying hydrostatic pressure to the sample.

Classes IPC  ?

• C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus

Abrégé

In one embodiment of the present disclosure, in order to increase production efficiency of astatine (At)-211, provided is a method for producing At by α-particle beam irradiation, and the method includes: an installation step S32 for receiving and arranging, in a housing part of a target material container (3), a target material (4) containing bismuth (Bi)-209; a rotation drive irradiation step S40 for irradiating at least a portion of the target material (4) with an α-particle beam (2) while rotating the target material container (3) around a rotation axis; a transportation step S46, after said step S40, for supplying a carrier gas and sending, through an exhaust pipe, an atmospheric gas around the target material; and a collection step S46 for collecting, from the atmospheric gas, astatine-211 generated from Bi by the irradiating with the α-particle beam. In a preferred embodiment of the present disclosure, the rotation drive irradiation step is performed with Bi of the target material in a solid state. Further, in a preferred embodiment of the present disclosure, the target material container is heated to a temperature higher than the melting point of Bi and lower than the boiling point of Bi in either or both of the transportation step or the collection step.

Classes IPC  ?

• G21K 5/08 - Supports pour cibles ou pour objets à irradier
• G21G 1/10 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p. ex. production d'isotopes radioactifs à l'extérieur des réacteurs nucléaires ou des accélérateurs de particules par bombardement avec des particules électriquement chargées
• G21K 1/00 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p. ex. pour focaliser ou pour modérer

Abrégé

A cell labeling molecule comprising a particle 101 having an identifiable property, an identification sequence 102 that is identifiable and corresponds to the property of the particle 101, a cleavable linker 103 that binds the particle 101 and the identification sequence 102, and a binding molecule 104 for binding to a cell, the binding molecule being bound to the identification sequence 102.

Classes IPC  ?

• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

Provided is an ATAC-seq method including: step (a) for contacting a transposome with a chromatin and tagmenting an open chromatin region to obtain a population of tagmented DNA fragments, wherein the transposome is a complex in which a DNA fragment having a transposase binding sequence and a desired nucleotide sequence is bound to the transposase bound, and each of the tagmented DNA fragments has the desired nucleotide sequence at the end; step (b) for amplifying and sequencing the population of the tagmented DNA fragments to obtain a population of reads; and step (c) for analyzing the population of the reads. In this ATAC-seq method, the desired nucleotide sequence includes a nucleotide sequence for amplification and a recognition sequence in this order in the 5'- to 3'-direction, and the amplification of the population of the tagmented DNA fragments is performed using a primer specific to a target region on the genomic DNA and a primer specific to the nucleotide sequence for amplification.

Classes IPC  ?

• C12Q 1/6869 - Méthodes de séquençage
• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
• C40B 40/06 - Bibliothèques comprenant des nucléotides ou des polynucléotides ou leurs dérivés

Abrégé

The present invention relates to a method for labeling a cell with a barcode. The method for labeling a cell with a barcode of the invention includes (1) for a cell group containing a plurality of single cells, directly or indirectly bringing a cell surface protein of the cell into contact with a modified barcode; or (2) directly or indirectly bringing a cell surface protein of a single cell into contact with a modified barcode.

Classes IPC  ?

• C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
• C12Q 1/6804 - Analyse d’acides nucléiques utilisant des immunogènes
• C12Q 1/6874 - Méthodes de séquençage faisant intervenir des réseaux d’acides nucléiques, p. ex. séquençage par hybridation [SBH]
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

A liquid jet generation device 100 according to the present embodiment generates and recovers a jet of a liquid in a vacuum, and comprises: a vacuum chamber 70; a discharge device 10 that discharges a liquid into the vacuum chamber; a catcher assembly 20 that has a skimmer 21 for recovering the liquid discharged from the discharge device; and a first positioning device 30 that positions the catcher assembly with respect to the liquid. It is thereby possible to form a liquid jet in a vacuum and recover the liquid from the vacuum.

Classes IPC  ?

• G01N 1/28 - Préparation d'échantillons pour l'analyse
• B05B 1/14 - Buses, têtes de pulvérisation ou autres dispositifs de sortie, avec ou sans dispositifs auxiliaires tels que valves, moyens de chauffage avec des orifices de sortie multiplesBuses, têtes de pulvérisation ou autres dispositifs de sortie, avec ou sans dispositifs auxiliaires tels que valves, moyens de chauffage avec des filtres placés dans ou à l'extérieur de l'orifice de sortie
• B05C 11/00 - Parties constitutives, détails ou accessoires non prévus dans les groupes
• B05C 11/10 - Stockage, débit ou réglage du liquide ou d'un autre matériau fluideRécupération de l'excès de liquide ou d'un autre matériau fluide
• G01N 23/083 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et mesurant l'absorption le rayonnement consistant en rayons X
• G21K 1/06 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p. ex. pour focaliser ou pour modérer utilisant la diffraction, la réfraction ou la réflexion, p. ex. monochromateurs
• G21K 5/02 - Dispositifs d'irradiation n'ayant aucun moyen pour former le faisceau
• G21K 5/10 - Dispositifs d'irradiation pourvus de dispositions permettant un mouvement relatif entre la source du rayonnement et l'objet à irradier

Abrégé

Provided is a system comprising a management server, a robot, and a sensor that measures an environment including a space of an action range of the robot. The management server is provided with: a reception unit that receives a mission; and a command unit that generates a command on the basis of the mission and transmits the command to the robot. The command includes a first command representing a state after execution of the mission. The robot is provided with: a state specification unit that specifies an environmental state of the robot including a state of an article handled by the robot on the basis of measurement data of the sensor; and an instruction unit that receives the command and drives the robot so that the state of the robot approaches a state represented by the command on the basis of the difference between the specified state and the state represented by the command.

Classes IPC  ?

• B25J 13/00 - Commandes pour manipulateurs
• G06Q 50/10 - Services

Abrégé

A feature extraction device extract features of a target from a plurality of images related to the target. The image processor calculates, using an image model, a likelihood of the inputted image belonging to a first image class, and a feature parameter of the inputted image. A feature processor that inputs an image included in the inputted image group into the image processor to calculate the likelihood and the feature parameter, selects, based on the calculated likelihood, a predetermined number of representative images from the inputted image group, and outputs, as feature information of the image group, the feature parameter calculated for the selected predetermined number of representative images. A classification processor is an additional element, inputs a target image group related to a target to the feature processor, and predicts, from the outputted feature information and using a classification model, whether the target belongs to a first target class. Here, an image belonging to the first image class corresponds to the target belonging to the first target class.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• A61B 8/08 - Applications cliniques
• G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
• G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
• G06V 20/50 - Contexte ou environnement de l’image

Abrégé

An object of the present invention is to a new method of producing a kidney organoid. The method for producing a kidney organoid is characterized by comprising culturing an early kidney organoid with a medium containing an RXR agonist and a PPAR agonist, wherein the kidney organoid includes matured proximal tubule cells.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• A61K 35/22 - UrineAppareil urinaire, p. ex. rein ou vessieCellules mésangiales intraglomérulairesCellules mésenchymateuses rénalesGlande surrénale
• A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

The present invention addresses the problem of providing a feature for forming large ribosomal subunits in vitro by a simpler method. The present invention relates to a large ribosomal subunit production method, the method comprising mixing a plurality of proteins or derivatives thereof for forming large ribosomal subunits with a plurality of RNAs or variants thereof for forming large ribosomal subunits in the presence of GTPase Der to form large ribosomal subunits. The present invention also relates to a ribosome production method, a peptide production method, and a kit.

Classes IPC  ?

• C12P 21/00 - Préparation de peptides ou de protéines
• C12N 9/16 - Hydrolases (3.) agissant sur les liaisons esters (3.1)
• C12N 15/09 - Technologie d'ADN recombinant

Abrégé

To improve the emission efficiency of ultraviolet light emitting diodes in the Far-UVC wavelength range, the ultraviolet light emitting diode in one embodiment has a semiconductor layer that includes aluminum, gallium and nitrogen. It may also include Indium. In various embodiments, it may include an AlGaN-based crystal or an InAlGaN-based crystal. The relative atomic ratios of aluminum, gallium, nitrogen and indium may vary at different positions in the layer. The diode comprises a light emitting layer, a spacer layer and an electron blocking layer in this order along the electron flow direction. The Al composition ratio in the spacer layer varies along the position in the thickness direction of the layers. The ultraviolet light emitting diode of the embodiment of the present disclosure can be provided with the emitting layer comprising at least one barrier layer and at least two quantum well layers sandwiching the barrier layer.

Classes IPC  ?

• H01L 33/14 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure contrôlant le transport des charges, p.ex. couche semi-conductrice fortement dopée ou structure bloquant le courant
• H01L 33/06 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure à effet quantique ou un superréseau, p.ex. jonction tunnel au sein de la région électroluminescente, p.ex. structure de confinement quantique ou barrière tunnel
• H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote

Abrégé

Provided are a data collection method, a data-collecting movement device, a trained model, a method for producing a trained model, an autonomous movement device, and a method for producing learning data that make it possible to improve accuracy of determination of a movement route by inference of machine learning. This data collection method is used for constructing a trained model used by an autonomous movement device in order to determine a host movement route in accordance with circumstances in the surroundings. A person moves a data-collecting movement device having a heteronomous movement mechanism under the circumstances in the surroundings (S22), and collects data representing the movement route of the data-collecting movement device under the circumstances in the surroundings from one or more sensors (S23). The heteronomous movement mechanism has a structure common to the movement mechanism of the autonomous movement device so as to enable movement simulating the movement of the autonomous movement device.

Classes IPC  ?

• G05D 1/43 - Commande de la position ou du cap par référence à un système à deux dimensions

Abrégé

The present invention relates to a fusion protein. A fusion protein according to the present invention contains a cyan fluorescent protein, a ligand-binding region of a peroxisome proliferator-activated receptor, and a yellow fluorescent protein, wherein the ligand-binding region of the peroxisome proliferator-activated receptor is included between the cyan fluorescent protein and the yellow fluorescent protein, and the coactivator peptide of the peroxisome proliferator-activated receptor is not included.

Classes IPC  ?

• C12N 15/62 - Séquences d'ADN codant pour des protéines de fusion
• C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
• C07K 19/00 - Peptides hybrides
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

The present invention addresses the problem of providing a method for detecting a target molecule more simply and safely than a conventional detection method by using a peptide aptamer specifically binding to a virus including influenza and other target molecules. The problem is solved by providing a detecting agent of a target molecule, comprising the following (1) and (2): (1) an alcohol-resistant peptide aptamer for the target molecule, containing an amino acid linked with a fluorescent molecule, and (2) an alcohol.

Classes IPC  ?

• G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
• C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides
• G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus

Abrégé

The present invention provides techniques for enabling estimation of the value of a perceived index. The present invention provides a system for estimating the value of a perceived index. The system comprises: a reception means for receiving the value of at least one objective index of a subject; an estimation means for estimating the value of a perceived index of the subject on the basis of the value of the at least one objective index; and an output means for outputting the estimated value or an output based on the estimated value. Typically, the estimation means estimates the value of the perceived index of the subject using a trained model.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne

Abrégé

A direct-current bus control system is provided for controlling power variation in a DC bus connecting an input power source and a load, including: a main stabilizer including a first charge/discharge element and a first power converter; and a plurality of sub-stabilizers each including a second charge/discharge element, a charge element, or a discharge element, and a second power converter. The plurality of sub-stabilizers include a first sub-stabilizer and a second sub-stabilizer including the charge element. When the voltage of the DC bus is higher than a first charge threshold, the second power converter of the first sub-stabilizer supplies a current equal to a current target value obtained by the second power converter of the first sub-stabilizer from the DC bus to the charge element of the first sub-stabilizer.

Classes IPC  ?

• H02J 1/12 - Fonctionnement de générateurs à courant continu en parallèle avec des convertisseurs, p. ex. avec un redresseur à arc de mercure
• H02J 1/04 - Systèmes d'alimentation en courant constant
• H02J 7/35 - Fonctionnement en parallèle, dans des réseaux, de batteries avec d'autres sources à courant continu, p. ex. batterie tampon avec des cellules sensibles à la lumière

Abrégé

A first light-receiving element of an embodiment of the disclosure includes: a semiconductor substrate including a photoelectric conversion region; a first first electrically-conductive region provided at a first surface interface of the semiconductor substrate and coupled to a first electrode; a second first electrically-conductive region provided around the first first electrically-conductive region and coupled to a second electrode, at the first surface interface; a third first electrically-conductive region in an electrically floating state provided around the second first electrically-conductive region, at the first surface interface; a first second electrically-conductive region having a different electrically-conductive type between the first first electrically-conductive region and the second first electrically-conductive region, at the first surface interface; and a fourth first electrically-conductive region provided at least between the first first electrically conductive region and the first second electrically-conductive region and having an impurity concentration lower than the first first electrically-conductive region, near the first surface interface.

Classes IPC  ?

• H01L 27/146 - Structures de capteurs d'images

Abrégé

A non-transitory computer-readable recording medium stores a program that causes a computer to execute a process performed in an information processing system. The process includes acquiring data with which at least one of a year, a month, a date, an hour, a minute, or a second is associated; extracting at least one analysis target from the data acquired at the acquiring; creating a graph of a cumulative value of a value relating to the analysis target with respect to a period; calculating a first area formed by the graph and an x-axis; and identifying a pattern of a graph shape based on the first area.

Classes IPC  ?

• G06Q 40/06 - Gestion de biensPlanification ou analyse financières
• G06F 18/28 - Détermination de motifs de référence représentatifs, p. ex. en faisant la moyenne ou en déformantGénération de dictionnaires
• G06T 11/20 - Traçage à partir d'éléments de base, p. ex. de lignes ou de cercles

Abrégé

The present invention addresses the problem of providing: a method for preparing a DNA library, in which method the RNA is amplified from an RNA material in an early stage of the procedure, thereby minimizing the loss of the RNA material in the procedure; and a method for performing the sequence determination and/or quantification of RNA molecules using this DNA library. The present invention provides a method for preparing a DNA library from a sample containing RNA. The method for preparing a DNA library comprises: (1) a step for attaching a first DNA linker to a 3' end of at least one RNA molecule in an RNA-containing sample to obtain an RNA molecule having the first DNA linker, wherein the first DNA linker includes at least a promoter antisense sequence; (2) a step for hybridizing a first oligonucleotide to the RNA molecule having the first DNA linker to obtain an RNA molecule having a double-stranded DNA promoter region, wherein the first oligonucleotide includes a promotor sense sequence; (3) a step for obtaining a complementary strand of an RNA molecule (complementary RNA) having the first DNA linker, by in vitro transcription with an RNA polymerase which starts transcription by recognizing a promoter sequence, using the RNA molecule having the double-stranded DNA promoter region as a template; and (4) a step for connecting a second DNA linker to the 3' end of the complementary RNA and performing reverse transcription using the complementary RNA having the second DNA linker as a template, to obtain a single-stranded DNA.

Classes IPC  ?

• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
• C12N 15/09 - Technologie d'ADN recombinant
• C12Q 1/6869 - Méthodes de séquençage
• C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
• C40B 40/06 - Bibliothèques comprenant des nucléotides ou des polynucléotides ou leurs dérivés

Abrégé

The present invention addresses the problem of providing a means for removing mutant mtDNA from a cell after homoplasmization of the cell. The present invention relates to: a homoplasmization promoter that comprises a reactive oxygen species or a chemical species which generates a reactive oxygen species in a cell, and a mitophagy promoter, or that comprises a substance that has the effect of generating a reactive oxygen species in a cell and the effect of promoting mitophagy; and a homoplasmization promotion method which uses the homoplasmization promoter. The present invention also relates to: a method for using the homoplasmization promotion method to prepare a homoplasmic cell; and a homoplasmic cell produced by said method.

Classes IPC  ?

• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
• A61K 31/365 - Lactones
• A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
• A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• A61Q 19/00 - Préparations pour les soins de la peau
• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
• C12N 15/09 - Technologie d'ADN recombinant

Abrégé

In order to improve the resolution of an image of a luminescent material excited by X-rays, an embodiment of the present disclosure provides a microscope 100 comprising an X-ray radiation unit and an observation optical system. The X-ray radiation unit 10 generates a patterned X-ray sheet beam 1 for illuminating an observation object 7. This patterned X-ray sheet beam has an intensity pattern 2 in which the intensity repeatedly varies with respect to a position in a certain direction included in the expansion in a partial region 32 of an expanding sheet region 3. The observation optical system 50 is arranged to receive radiation of an observation wavelength from an observation region 4, the observation region including at least a portion of the partial region. An embodiment of the present disclosure also provides a method for capturing an image of a luminescent material.

Classes IPC  ?

• G21K 7/00 - Microscopes à rayons gamma ou à rayons X
• G02B 5/18 - Grilles de diffraction
• G02B 21/06 - Moyens pour éclairer un échantillon
• G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
• G21K 1/00 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p. ex. pour focaliser ou pour modérer
• G21K 1/06 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p. ex. pour focaliser ou pour modérer utilisant la diffraction, la réfraction ou la réflexion, p. ex. monochromateurs
• G21K 5/02 - Dispositifs d'irradiation n'ayant aucun moyen pour former le faisceau

Abrégé

A propulsion strengthening member attached to a surface of an object existing in outer space, the propulsion strengthening member includes: a transparent member that transmits an emitted laser; and an opaque member that is provided between the transparent member and the object and absorbs the laser such that at least a part thereof is evaporated by energy of the laser.

Classes IPC  ?

• B32B 27/08 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique d'une résine synthétique d'une sorte différente
• F41H 13/00 - Moyens d'attaque ou de défense non prévus ailleurs

Abrégé

A training device according to one aspect of the present disclosure trains a model that evaluates text, in a document format, with respect to a prescribed issue. The training device includes: a first user interface provision unit that provides a first user interface capable of at least designating data for training the model; and a training unit that trains the model on the basis of the training data and index values representing the degree of contribution to the quality of the model.

Classes IPC  ?

• G06Q 50/20 - Éducation

Abrégé

The present invention provides novel technology which makes it possible to control the function of a protein in the living body of mouse with high temporal resolution.　Provided is a genetically modified mouse, said genetically modified mouse comprising: a pair of Cre recombinase recognition sequences; a transcription termination polyA sequence that is located between the pair of Cre recombinase recognition sequences; a transport inhibitor response 1 (TIR1) family gene sequence that is located downstream of the pair of Cre recombinase recognition sequences and that codes for a TIR1 family protein; and a promoter sequence that is located upstream of the pair of Cre recombinase recognition sequences, and that can drive expression of the TIR1 family gene after recombination of the pair of Cre recombinase recognition sequences.

Classes IPC  ?

• A01K 67/027 - Nouvelles races ou races modifiées de vertébrés
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
• C12N 15/12 - Gènes codant pour des protéines animales

Abrégé

The present invention relates to a gel structure containing a gel composition that contains at least one anisotropic nanostructure, at least one liquid, and at least one polymer having a crosslinked structure. In a static state, the gel structure has at least one surface. The major axes of each of the at least one anisotropic nanostructure are oriented almost in parallel to each other and in non-parallel and non-perpendicular to the aforesaid at least one surface.

Classes IPC  ?

• C08L 101/14 - Compositions contenant des composés macromoléculaires non spécifiés caractérisées par des propriétés physiques, p. ex. anisotropie, viscosité ou conductivité électrique les composés macromoléculaires étant solubles dans l'eau ou gonflables dans l'eau, p. ex. gels aqueux
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08K 3/04 - Carbone
• C08K 3/22 - OxydesHydroxydes de métaux
• C08L 33/26 - Homopolymères ou copolymères de l'acrylamide ou de la méthacrylamide
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12N 1/00 - Micro-organismes, p. ex. protozoairesCompositions les contenantProcédés de culture ou de conservation de micro-organismes, ou de compositions les contenantProcédés de préparation ou d'isolement d'une composition contenant un micro-organismeLeurs milieux de culture

Abrégé

One embodiment provides a novel method that allows evaluation of receptor tyronsine kinase (RTK) activity. The present invention relates to a method for evaluating RTK activity, the method comprising: a step (A1) of determining the diffusion kinetics A1 of a labeled RTK by bringing a substance of interest into contact with cells that express said RTK on the cell membrane; a step (B1) of determining the diffusion kinetics B1 of a labeled RTK by bringing a substance of interest and a ligand that activates said RTK into contact with cells that express said RTK on the cell membrane; a step (C1) of calculating the ratio between the diffusion kinetics A1 of the RTK obtained by said step (A1) and the diffusion kinetics B1 of the RTK obtained by said step (B1); and a step (D1) of evaluating the effect of the substance of interest on RTK activity by comparing the ratio of diffusion kinetics obtained in step (C1) with a threshold value. In step (D1), the ratio of diffusion kinetics obtained in step (C1) being above the threshold value can indicate that the substance of interest has an effect on the molecular function of the RTK.

Classes IPC  ?

• C12Q 1/48 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une transférase
• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• G01N 33/15 - Préparations médicinales
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes

Abrégé

The present invention provides a novel polyester resin that exhibits biodegradability in seawater, and a method for producing the polyester resin. The ocean-biodegradable polyester resin contains a polymer having: a structural unit derived from succinic acid; a structural unit derived from a dicarboxylic acid having 7 or more carbon atoms; and a structural unit derived from at least one aliphatic diol selected from the group consisting of ethylene glycol, 1,2-propanediol and 1,3-propanediol.

Classes IPC  ?

• C08G 63/16 - Acides dicarboxyliques et composés dihydroxylés
• C08L 101/16 - Compositions contenant des composés macromoléculaires non spécifiés les composés macromoléculaires étant biodégradables

Abrégé

The present invention provides a polyester amide resin having excellent gas barrier properties and biodegradability, and a method for producing the polyester amide resin. The polyester amide resin contains a polymer having: a structural unit (A) derived from succinic acid; a structural unit (B) derived from a dicarboxylic acid having 5 or more carbon atoms; a structural unit (C) derived from an aliphatic diol, and a structural unit (D) derived from an amino acid.

Classes IPC  ?

• C08G 69/44 - Polyesteramides
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08L 101/16 - Compositions contenant des composés macromoléculaires non spécifiés les composés macromoléculaires étant biodégradables

Abrégé

A non-destructive inspection device includes a neutron generation portion, a neutron shield portion, a gamma ray detector, and a gamma ray shield portion. The neutron generation portion emits neutrons spontaneously, or emits neutrons by DD nuclear fusion reaction or DT nuclear fusion reaction. The neutron shield portion is covers the neutron generation portion from at least an area around the neutron generation portion and thereby shields the neutrons at the area, and allows the neutrons to be emitted to a front side of the neutron generation portion. The gamma ray detector detects gamma rays generated in an inspection object on a front side of the neutron generation portion. The gamma rays are generated by the neutrons incident on the inspection object. The neutron shield portion, the gamma ray shield portion, and the gamma ray detector are arranged in this order in alignment with each other in a lateral direction.

Classes IPC  ?

• G01N 23/222 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux utilisant l'analyse par activation en utilisant l'analyse par activation neutronique [NAA]
• G01N 33/38 - BétonChauxMortierPlâtreBriquesProduits céramiquesVerre

Abrégé

A laser amplification medium includes: a clad part; a first core part and a second core part; a virtual first, second, and third layers. The first core part and the second core part extend parallel to an axis direction. The first layer includes the first core part, the second core part, and a part of the clad part. The second layer and the third layer include a part of the clad part. Each side face of the first core part and the second core part includes a first planar portion and a second planar portion. The first planar portion is included in a first surface of the first layer, the first surface being a virtual bonding interface with the second layer. The second planar portion is included in a second surface of the first layer, the second surface being a virtual bonding interface with the third layer.

Classes IPC  ?

• H01S 3/067 - Lasers à fibre optique
• H01S 3/00 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet
• H01S 3/02 - Détails de structure

Abrégé

In order to realize a far-ultraviolet irradiation device having increased output, an embodiment of the present disclosure provides a lens-attached irradiation device 100. In the lens-attached irradiation device, a module 1 is disposed in each of a plurality of element sites 10 forming a planar array, the module 1 having a radiating direction in a direction 90 normal to the planar array. The module 1 comprises: an ultraviolet light emitting diode (UVLED) element which includes an AlGaN-based crystal or InAlGaN-based crystal and emits a far-ultraviolet ray with a wavelength from 220 nm to 240 nm; and a lens 6 which is disposed in a far-ultraviolet radiating path corresponding to each UVLED element, and which is transmissive to the wavelength. An embodiment of the present disclosure further provides a reflector-attached irradiation device comprising: UVLED elements disposed in a plurality of element sites forming a planar array; and a reflector having a reflecting surface for reflecting a far-ultraviolet ray inclined from the radiating direction of the UVLED element in the radiating direction.

Classes IPC  ?

• H01L 33/60 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments de mise en forme du champ optique Éléments réfléchissants
• B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaireAppareils à cet usage utilisant des radiations électromagnétiques
• H01L 33/00 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails
• H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote
• H01L 33/58 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments de mise en forme du champ optique
• H01L 33/62 - Dispositions pour conduire le courant électrique vers le corps semi-conducteur ou depuis celui-ci, p.ex. grille de connexion, fil de connexion ou billes de soudure
• H01L 33/64 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments d'extraction de la chaleur ou de refroidissement

Abrégé

To provide a synthesis scheme capable of easily synthesizing various kinds of fluorescent probes. A method for preparing a compound represented by Formula (III) below, the method including steps (1) to (5). To provide a synthesis scheme capable of easily synthesizing various kinds of fluorescent probes. A method for preparing a compound represented by Formula (III) below, the method including steps (1) to (5).

Classes IPC  ?

• C07F 9/38 - Acides phosphoniques [R—P(:O)(OH)2]Acides thiophosphoniques
• C12Q 1/37 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase faisant intervenir une peptidase ou une protéinase

Abrégé

[Problem] The purpose of the present disclosure is to provide a protein selectively recognizing cancer caused by a mutation of K-Ras gene (referred to herein as "K-Ras gene mutation cancer"). [Solution] Provided are: a method for producing a protein selectively recognizing K-ras gene mutation cancer, the method being characterized by including first to third steps for linking first to third specific sugar chains respectively to lysine residues on a protein molecule; and a protein produced by this method. Also provided is a pharmaceutical composition for cancer treatment, the pharmaceutical composition containing the protein.　

Classes IPC  ?

• C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
• A61K 38/38 - Albumines
• A61K 47/61 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique le composé organique macromoléculaire étant un polysaccharide ou l’un de ses dérivés
• A61P 35/00 - Agents anticancéreux
• C07K 1/13 - Marquage de peptides
• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères

Abrégé

Provided are an iridium-manganese oxide composite material and an iridium-manganese oxide composite electrode material that are inexpensive and have high catalytic activity for use in an anode catalyst for oxygen evolution associated with water electrolysis. Also provided are methods for producing the same. An iridium-manganese oxide composite material includes a manganese oxide and iridium distributed on at least a surface of the manganese oxide, the iridium having a metal valence of 3.1 or greater and 3.8 or less. An iridium-manganese oxide composite electrode material includes a conductive substrate formed of a fiber, with the iridium-manganese oxide composite material being coated on at least a portion of the conductive substrate.

Classes IPC  ?

• C25B 11/093 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un métal noble ou oxyde de métal noble et au moins un oxyde d’un métal non noble
• C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
• C25B 1/21 - Oxydes de manganèse
• C25B 9/23 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes comprenant des membranes échangeuses d'ions dans ou sur lesquelles est incrusté du matériau pour électrode
• C25D 9/04 - Revêtement électrolytique autrement qu'avec des métaux avec des matières inorganiques

Abrégé

This non-destructive inspection system 1 has a non-destructive inspection device 2 and a management device 3. The non-destructive inspection device 2 is provided with: a neutron emission unit 10 capable of emitting a neutron beam; a gamma ray detection unit 20 capable of detecting gamma rays; a device casing 30 covering the neutron emission unit 10 and the gamma ray detection unit 20, an opening 30a being formed in the device casing 30; an outer shutter 31 that opens/closes the opening 30a; dose monitors 51, 52, 53 provided to the device casing 30, the dose monitors 51, 52, 53 detecting the radiation dose; a device communication unit 56 capable of transmitting device information including the detected radiation dose to the management device 3, and capable of receiving inspection permission information from the management device 3; and a device control unit 40 that, when the inspection permission information is acquired, opens the outer shutter 31 and enables emission of a neutron beam from the neutron emission unit 10.

Classes IPC  ?

• G01N 23/222 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux utilisant l'analyse par activation en utilisant l'analyse par activation neutronique [NAA]
• G01T 1/02 - Dosimètres
• G01T 7/12 - Dispositions pour actionner un signal d'alarme

Abrégé

Provided are a disease risk evaluation method, a disease risk evaluation system and a health information processing device, whereby it becomes possible to detect the latent onset tendency in a healthy stage in advance and to quantify the prospective disease risk of a disease of interest. Each of the disease risk evaluation method, the disease risk evaluation system and the health information processing device according to the present invention includes a plurality of steps, i.e., a step for classifying into a group in which the susceptibility to developing a specific disease is high and a group in which the susceptibility to developing the specific disease is low regardless of the degree of progression of the disease from a healthy stage until the onset of the disease, and a step for further classifying the degrees of the development of the disease in a group in which the incidence risk is determined as high. Each of the disease risk evaluation method, the disease risk evaluation system and the health information processing device is characterized by being achieved by changing the type of data to be used in a data-driven analysis in each of the steps.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne

Abrégé

A structure for optical observation according to the present disclosure is obtained by sequentially arranging a liquid immersion objective lens, an immersion liquid, a light-transmitting sample placement member, and a sample that has been processed with a mounting liquid in the stated order on the optical axis of the liquid immersion objective lens. In the visible light region, the refractive index difference and the Abbe number difference between the immersion liquid and the mounting liquid are both 5% or less.

Classes IPC  ?

• G02B 21/00 - Microscopes
• G01N 21/64 - FluorescencePhosphorescence

Abrégé

The present disclosure addresses the problem of providing a novel compound that has the basic structure of furanocoumarin and is useful as a medicine.　The present embodiment is a compound represented by formula (I) or a salt thereof (in formula (I), R11-61-6 alkyl group; R21-201-63-203-201-61-61-201-20-alkyl group; and Ar1and Ar25-203-203-20 heteroaryl group).

Classes IPC  ?

• C07D 493/04 - Systèmes condensés en ortho
• A61K 31/37 - Coumarines, p. ex. psoralène
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
• A61P 31/12 - Antiviraux
• C07D 493/02 - Composés hétérocycliques contenant des atomes d'oxygène comme uniques hétéro-atomes dans le système condensé dans lesquels le système condensé contient deux hétérocycles

Abrégé

Provided are a composition and a method for inhibiting the reverse transcription of a ribosomal RNA. This composition for inhibiting the reverse transcription of a ribosomal RNA is characterized by containing a polymer having at least one functional group selected from the group consisting of sulfuric acid groups, sulfone groups, and basic groups thereof, and by being used in an amount such that the polymer concentration in a reverse transcription reaction solution is 10 pg/μL or more.

Classes IPC  ?

• C12Q 1/6848 - Réactions d’amplification d’acides nucléiques caracterisées par les moyens d’empêcher la contamination ou d’augmenter la spécificité ou la sensibilité d’une réaction d’amplification
• C12Q 1/686 - Réaction en chaine par polymérase [PCR]
• C12Q 1/6851 - Amplification quantitative
• C12Q 1/6869 - Méthodes de séquençage

Abrégé

Provided is a component analyzing device 1 including: a projection unit 11 which projects light on an object; a measurement unit 12 which detects reflected light, scattered light, or emitted light from the object and measures a content of a related substance, which is contained together with a target substance in the object, from a detection result; and an estimation unit 13 which estimates a content of the target substance from a measurement result of the content of the related substance, based on a quantitative relationship between the target substance and the related substance derived from a reaction equation system based on a biosynthetic metabolic pathway of the object.

Classes IPC  ?

• G16C 20/20 - Identification d’entités moléculaires, de leurs parties ou de compositions chimiques
• G01N 21/65 - Diffusion de Raman
• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes

Abrégé

An object of the present invention is to provide a method for producing a retinal cell or retinal tissue with a reduced proportion of non-target cells in differentiating pluripotent stem cells. The method of the present invention for producing a retinal cell or retinal tissue comprises: (A) suspension-culturing a pluripotent stem cell to form a cell aggregate of pluripotent stem cells; and (B) suspension-culturing the cell aggregate obtained in the step (A) in the presence of a BMP signaling pathway agonist and a CHK1 signaling pathway inhibitor to obtain a cell aggregate containing a retinal cell.

Classes IPC  ?

• A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
• C12N 5/079 - Cellules neurales

Abrégé

A non-transitory computer-readable recording medium stores therein a path selecting program that causes a computer to execute a process including extracting a plurality of representative points from a presence probability distribution of states of a target, identifying a first plurality of state transition paths between the plurality of representative points, and selecting a second plurality of state transition paths from the first plurality of state transition paths, based on a probability density of each path included in the first plurality of state transition paths.

Classes IPC  ?

• G06N 5/04 - Modèles d’inférence ou de raisonnement

Abrégé

A non-transitory computer-readable recording medium stores therein an information output program that causes a computer to execute a process including acquiring a first point and a second point in a presence probability distribution of a state of an object, specifying a plurality of points serving as candidates for a transition destination from the first point, selecting a third point from the points based on a distance from the first point to each of the points and probability during transition, and outputting a transition path from the first point to the second point including the third point as state transition information on the object.

Classes IPC  ?

• G06N 7/00 - Agencements informatiques fondés sur des modèles mathématiques spécifiques

Abrégé

The death of some pluripotent stem cells in suspension culture of pluripotent stem cells is avoided. When performing the suspension culture of the pluripotent stem cells, a liquid medium that does not substantially contain a PKCβ inhibitor is used for a single-cell state and a liquid medium containing a PKCβ inhibitor and a WNT inhibitor is used after a cell mass is formed.

Classes IPC  ?

• C12N 5/074 - Cellules souches adultes
• C12N 5/0735 - Cellules souches embryonnairesCellules germinales embryonnaires

Abrégé

A thrust generating device according to the present invention is a thrust generating device for irradiating a target with a laser beam to generate thrust for the target, the thrust generating device including: a laser beam generating device that generates a first laser beam having a first wavelength and a second laser beam having a second wavelength different from the first wavelength; and an irradiation device that simultaneously irradiates the target with the first laser beam and the second laser beam. The second wavelength may be a wavelength having a high absorptivity in the target than the first wavelength, and the intensity of the second laser beam may be lower than that of the first laser beam. Further, the second laser beam may be generated by converting the wavelength of the first laser beam.

Classes IPC  ?

• B64G 1/10 - Satellites artificielsSystèmes de tels satellitesVéhicules interplanétaires
• G02F 1/35 - Optique non linéaire
• G02F 1/39 - Optique non linéaire pour la génération ou l'amplification paramétrique de la lumière, des infrarouges ou des ultraviolets

Abrégé

The present disclosure provides an artificial adjuvant vector cell inducing an immune response to a spike protein of a coronavirus, a pharmaceutical composition containing the cell, and use of the cell and the composition. According to the present disclosure, the cell can be an artificial adjuvant vector cell (aAVC) expressing a spike protein of a coronavirus.

Classes IPC  ?

• A61K 39/215 - Coronaviridae, p. ex. virus de la bronchite infectieuse aviaire
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• A61P 35/00 - Agents anticancéreux
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• C07K 14/74 - Complexe majeur d'histocompatibilité [MHC]

Abrégé

The present invention provides a transplant material of a retinal pigment epithelial cell that can be prepared in a short time at a low cost, and that can be easily controlled at the site of transplantation even though the transplantation method is non-invasive, and a method for producing such transplant material.

Classes IPC  ?

• A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C12N 5/079 - Cellules neurales

Abrégé

A spider mite repellent comprises at least one oil selected from the group consisting of olive oils, olive pomace oils, and partially hydrogenated high-oleic rapeseed oils as an active ingredient.

Classes IPC  ?

• A01N 65/08 - Magnoliopsida [dicotylédones]
• A01N 25/30 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles caractérisés par les agents tensio-actifs
• A01P 17/00 - Répulsifs des animaux nuisibles

Abrégé

A tomographic image processing device generates a pseudo tomographic image from a moving image in which a cross section is captured via a light-receiving surface of a puncture member that punctures a living body. Herein, an acquirer acquires the moving image in which the cross section is captured via the light-receiving surface of the puncture member that punctures the living body. A corrector performs image correction of each frame of the moving image, based on a shape of the light-receiving surface. A tracker tracks a candidate for a picture of tissue of the living body that satisfies a desired tracking condition. An estimator estimates a representative vector, based on a movement vector of the candidate. An extractor extracts a candidate in which the movement vector is similar to the representative vector. A calculator calculates, based on a drawing position in a frame in which a picture of the extracted candidate is drawn in the moving image and an order of the frame, an arrangement position in which the picture of the candidate needs to be arranged. A generator generates a pseudo tomographic image of the living body by drawing the picture of the extracted candidate in the calculated arrangement position.

Classes IPC  ?

• A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
• G01N 21/64 - FluorescencePhosphorescence
• G06T 7/00 - Analyse d'image
• G06T 11/00 - Génération d'images bidimensionnelles [2D]

Abrégé

A novel fluorescent protein and uses thereof are provided. A polypeptide of the present invention has a fluorescence property, the polypeptide being indicated in any one of (1) to (3) below: (1) a polypeptide having an amino acid sequence set forth in SEQ ID NO: 1; (2) a polypeptide having an amino acid sequence set forth in SEQ ID NO: 1, the amino acid sequence having replaced, deleted, inserted, and/or added therein not less than 1 and not more than 32 amino acids; and (3) a polypeptide having not less than 85% sequence identity with respect to an amino acid sequence set forth in SEQ ID NO: 1.

Classes IPC  ?

• C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• C12N 15/86 - Vecteurs viraux
• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées

Abrégé

The present invention relates to a therapeutic drug for a disease accompanied by a disorder in retinal cells or a retinal tissue, the drug including a retinal tissue, the retinal tissue being of an allogeneic origin and having a three-dimensional structure, wherein an intended patient to be given the therapeutic drug is a patient affected by a disease accompanied by a disorder of retinal cells or a retinal tissue, to be given systemically, for 1 month or more after the administration of the therapeutic drug, no immunosuppressive agent aimed at preventing graft rejection.

Classes IPC  ?

• A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
• A61L 27/38 - Cellules animales

Abrégé

The spirosolane skeleton 23-position hydroxylase gene and the spirosolane skeleton 23-position acetyltransferase gene derived from S. chacoense, S. tuberosum, and S. lycopersicum are found to be involved with the biosynthesis of leptine, which achieves resistance against Colorado potato beetle.

Classes IPC  ?

• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• A01H 1/00 - Procédés de modification des génotypes
• A01H 6/82 - Solanaceae, p. ex. poivron, tabac, pomme de terre, tomate ou aubergine
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées

Abrégé

To increase the ceiling of operating temperature of quantum cascade lasers in THz range, the quantum cascade laser element of the present disclosure has a semiconductor superlattice structure with an active region that emits electromagnetic waves of a certain frequency in the THz range under the external voltage applied through a pair of electrodes for operation. The quantum well structure of the unit structure that comprises this semiconductor superlattice structure has quantum levels of electrons in an isolated three-level structure. In one example, each unit structure has a two-quantum well structure having a first well layer and a second well layer, which are separated from each other by a barrier layer, the first well layer including a first sublayer, a second sublayer with a composition different from that of the first sublayer, and a third sublayer, which has the same composition as the first sublayer.

Classes IPC  ?

• H01S 5/34 - Structure ou forme de la région activeMatériaux pour la région active comprenant des structures à puits quantiques ou à superréseaux, p. ex. lasers à puits quantique unique [SQW], lasers à plusieurs puits quantiques [MQW] ou lasers à hétérostructure de confinement séparée ayant un indice progressif [GRINSCH]
• H01S 5/343 - Structure ou forme de la région activeMatériaux pour la région active comprenant des structures à puits quantiques ou à superréseaux, p. ex. lasers à puits quantique unique [SQW], lasers à plusieurs puits quantiques [MQW] ou lasers à hétérostructure de confinement séparée ayant un indice progressif [GRINSCH] dans des composés AIIIBV, p. ex. laser AlGaAs

Abrégé

A light-receiving element according to an embodiment of the present disclosure includes: a semiconductor substrate including a photoelectric conversion region; a first first electrically-conductive region provided at an interface of a first surface of the semiconductor substrate and coupled to a first electrode; a second first electrically-conductive region provided at the interface of the first surface and around the first first electrically-conductive region and coupled to a second electrode; a third first electrically-conductive region provided at the interface of the first surface and around the second first electrically-conductive region and being in an electrically floating state; and an electrically-conductive film provided above the first surface at least between the first first electrically-conductive region and the second first electrically-conductive region.

Classes IPC  ?

• H01L 27/146 - Structures de capteurs d'images
• G01T 1/24 - Mesure de l'intensité de radiation avec des détecteurs à semi-conducteurs

Abrégé

The present invention relates to a compound represented by the following formula (I): The present invention relates to a compound represented by the following formula (I): The present invention relates to a compound represented by the following formula (I): and an antimalarial drug comprising the compound.

Classes IPC  ?

• C07D 207/273 - Pyrrolidones-2 avec des hétéro-atomes ou des atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux autres atomes de carbone du cycle
• A61K 31/4015 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil ayant des groupes oxo liés directement à l'hétérocycle, p. ex. piracétam, éthosuximide
• A61P 33/06 - Antipaludéens

Abrégé

A nondestructive inspection system 1 is provided with: a neutron radiation unit 10 capable of radiating a first neutron dose of neutrons; a neutron detection unit 20 capable of detecting a second neutron dose of neutrons scattered inside an inspection object A upon radiation of neutrons from the neutron radiation unit 10; a gamma ray detection unit 30 capable of detecting a gamma ray dose released from the inspection object A upon radiation of neutrons from the neutron radiation unit 10; and an analysis unit 50 that calculates the contained amount of a predetermined substance on the basis of the gamma ray dose and corrects the contained amount of the predetermined substance on the basis of the first neutron dose and the second neutron dose.

Classes IPC  ?

• G01N 23/222 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux utilisant l'analyse par activation en utilisant l'analyse par activation neutronique [NAA]
• G01N 23/204 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en utilisant la diffraction de la radiation par les matériaux, p. ex. pour rechercher la structure cristallineRecherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en utilisant la diffusion de la radiation par les matériaux, p. ex. pour rechercher les matériaux non cristallinsRecherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en utilisant la réflexion de la radiation par les matériaux en mesurant la rétrodiffusion en utilisant des neutrons
• G01N 23/2206 - Combinaison de plusieurs mesures, l'une au moins étant celle d’une émission secondaire, p. ex. combinaison d’une mesure d’électrons secondaires [ES] et d’électrons rétrodiffusés [ER]

Abrégé

A computer-implemented method for detecting objects in the field of view of an optical detection device is provided that includes (i) acquiring, through the optical detection device, a plurality of subsequent frames of a portion of an observed space in a time interval, wherein each frame is acquired in a corresponding time instant of the time interval; (ii) selecting a subset of frames from the plurality of frames; (iii) for each set of values of shifting parameters of a plurality of sets of values of shifting parameters that are indicative corresponding predetermined motions of an object with respect to the optical detection device, determining a corresponding first stacked frame on the basis of the subset of frames and as a function of the set of values of the shifting parameters; (iv) for each first stacked frame, determining whether the first stacked frame belongs to a first or a second class, wherein the first and the second class are respectively indicative of the presence or absence of an image of an object in the first stacked frame; and (v) selecting, among the sets of values of shifting parameters, each set of values of shifting parameters that is associated to corresponding first stacked frame classified as belonging to the first class. The method further includes, for each selected set of values of shifting parameters: (i) determining a corresponding second stacked frame on the basis of the set of frames and as a function of the selected set of values of shifting parameters; (ii) for each second stacked frame, determining whether the second stacked frame belongs to a third or a fourth class wherein the third and the fourth class are respectively indicative of the presence or absence of an image of an object in the second stacked frame; (iii) determining if the first stacked frame classified as belonging to the first class and in the second stacked frame classified as belonging to the third class meet a requirement; and (iv) if the requirement is met, indicate the presence of an object.

Classes IPC  ?

• G06T 7/246 - Analyse du mouvement utilisant des procédés basés sur les caractéristiques, p. ex. le suivi des coins ou des segments

Abrégé

A high-temperature tank includes an optical window which transmits a laser and is provided at one end, and a right-angle conical mirror which is provided at the other end, has an opening at the apex, and which reflects laser light incident from the optical window towards the one end in an area other than opening. A magnetic field generator generates a magnetic field in the region of intersection of the laser reflected by the right-angle conical mirror. A magnetic field gradient attenuation module locally attenuates the gradient of the magnetic field generated by the magnetic field generator.

Classes IPC  ?

• H03L 7/26 - Commande automatique de fréquence ou de phaseSynchronisation utilisant comme référence de fréquence les niveaux d'énergie de molécules, d'atomes ou de particules subatomiques
• G04F 5/14 - Appareils pour la production d'intervalles de temps prédéterminés, utilisés comme étalons utilisant des horloges atomiques