Abrégé

Provided is a magnetic thin film robot, which comprises a cardiac outer wrapping film module and a control module connected to each other. The cardiac outer wrapping film module comprises a non-magnetic supporting part and a magnetic driving part, and the non-magnetic supporting part and the magnetic driving part are mutually coupled. The control module comprises a patch-type magnetic field generator and a power supply assembly connected to each other, and the magnetic field generator in vitro corresponds to the magnetic driving part in vivo in terms of space. A magnetic field is generated through the control module, and the magnetic field drives the cardiac outer wrapping film module to provide heart failure assistance.

Classes IPC  ?

• A61B 34/30 - Robots chirurgicaux
• A61M 60/191 - Pompes ou dispositifs de pompage implantables, c.-à-d. que le sang est pompé à l’intérieur du corps du patient implantables dans ou sur le cœur, ou autour du cœur agissant mécaniquement sur l’extérieur du cœur natif du patient, p. ex. structures compressives placées autour du cœur
• A61M 60/289 - Dispositifs de circulation mécanique pour assistance de la fonction cardiaque résiduelle par action mécanique sur le cœur natif ou la structure de vaisseaux sanguins du patient, p. ex. dispositifs de compression cardiaque directe
• A61M 60/489 - Détails concernant l’entraînement pour des dispositifs d’actionnement circulatoire mécanique la force agissant sur les moyens d’actionnement étant magnétique
• A61M 60/492 - Détails concernant l’entraînement pour des dispositifs d’actionnement circulatoire mécanique la force agissant sur les moyens d’actionnement étant magnétique générée par des aimants permanents
• A61M 60/495 - Force électromagnétique

Abrégé

The present invention relates to the field of model testing, in particular to a low-intensity intermittent stress model and an apparatus. The model and the apparatus comprise: observing a target body within a set time, wherein the set time comprises five time period groups, and each time period group comprises three days. The responses of the target body to corresponding stresses are obtained by means of the stress observation of each group of three days.

Classes IPC  ?

• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients

Abrégé

Provided in the present invention are a radiology report generation method and apparatus, and a terminal and a storage medium. The method comprises: inputting a radiology image to be processed into a pre-trained dynamics priori network model, wherein the dynamics priori network model comprises a dynamic knowledge graph network, a prior knowledge network and a decoder; in the dynamic knowledge graph network, obtaining a dynamic knowledge graph on the basis of the radiology image, and obtaining a visual representation on the basis of the dynamic knowledge graph; acquiring prior knowledge information corresponding to the radiology image, and on the basis of the prior knowledge information and the visual representation, using the prior knowledge network to obtain a prior representation vector; and inputting the visual representation and the prior representation vector into the decoder to generate a radiology report corresponding to the radiology image. In the present invention, the radiology report is generated by combining the dynamic knowledge graph with the prior knowledge information, such that visual and textual biases caused by limited data availability can be better handled, thereby improving the report generation quality.

Classes IPC  ?

• G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission

Abrégé

Provided are a preparation process for a modified hydroxyapatite and the use thereof. The preparation process comprises the following steps: S1. removing impurities from coral by using a sodium hypochlorite solution, followed by crushing to obtain coral particles; S2. subjecting the coral particles and a phosphate solution to a hydrothermal reaction at a pH value of 9-11 to obtain coralline hydroxyapatite; S3. mixing and reacting the coralline hydroxyapatite and an ion source to obtain an ion source-doped coralline hydroxyapatite; and S4. heating the ion source-doped coralline hydroxyapatite, and sintering and cooling same to obtain an ion source-doped coralline β-tricalcium phosphate, wherein the ion source comprises a strontium source. The modified hydroxyapatite prepared by the preparation process has a better degradation performance and mechanical adaptability, which improves the biological activity and osteoinductivity of coral artificial bones, and facilitates bone tissue ingrowth.

Classes IPC  ?

• C01B 25/32 - Phosphates de magnésium, de calcium, de strontium ou de baryum
• A61L 27/12 - Matériaux contenant du phosphore, p. ex. apatite
• A61L 27/58 - Matériaux au moins partiellement résorbables par le corps

Abrégé

Disclosed in the present invention are a flexible and isotropically stretchable electrode device, and a preparation method therefor and the application thereof. The preparation method comprises the following steps: (1) preparing a silicone substrate, wherein the silicone substrate is an ecoflex 00-20 silicone substrate; (2) using a mask to prepare a patterned electrode on the silicone substrate by means of evaporation; (3) encapsulating a front end to complete the preparation of a flexible part of a device; and (4) connecting soft and hard interfaces and performing encapsulation to complete the preparation of the device. In the present invention, ecoflex 00-20 is used to prepare a silicone substrate of the device, and a patterned electrode is prepared by means of evaporation, thereby finally obtaining the flexible and isotropically stretchable electrode device. The device integrates multiple functions, has a resistance value increasing with tensile deformation, can serve as a deformation sensor to reflect the real-time capacity of a bladder, and further has good impedance stability and potential for long-term implantation.

Classes IPC  ?

• H05K 3/18 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué au support isolant de manière à former le parcours conducteur recherché utilisant la technique de la précipitation pour appliquer le matériau conducteur
• A61B 5/20 - Mesure des fonctions urologiques
• A61B 5/296 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électromyographie [EMG]
• A61B 5/391 - Électromyographie [EMG] des organes génito-urinaires

Abrégé

The present application discloses a gene point mutation mouse model construction method, comprising: by taking T274M mutation on Kcnq2 Exon6 as a target, designing sgRNA and ssODN; selecting a female mouse of a set week age as an ovum donor, injecting a certain dose of serum gonadotropin and human chorionic gonadotropin into the abdominal cavity of the female mouse, then mating the female mouse with a mating male mouse, and collecting zygotes of the mated female mouse; injecting Cas9 protein, ssODN and sgRNA into the pronuclei of the zygotes by means of a microinjection technique, transplanting the zygotes obtained after injection into the ampulla of the fallopian tube of a surrogate female mouse, and obtaining a neonatal mouse after the pregnant female mouse gives birth; respectively designing a pair of identification primers F1, R1 at two ends of a mutation site on the basis of a Kcnq2 gene point mutation site, identifying the neonatal mouse, and screening out a Kcnq2T274M/+ point mutant mouse in which T274M mutation is successfully knocked.

Classes IPC  ?

• C12N 15/89 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p. ex. co-transformation utilisant la micro-injection
• C12N 15/12 - Gènes codant pour des protéines animales
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
• C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
• A01K 67/027 - Nouvelles races ou races modifiées de vertébrés

Abrégé

The present application relates to the technical field of detection of the curing shrinkage rates of adhesives, and more specifically relates to an experimental determination method for the curing shrinkage rate of an adhesive. The method comprises the following steps: step 1, preparing a binary warping sample composed of an adhesive and an elastic material; step 2, curing the sample according to standard adhesive curing steps; step 3, placing the cured sample in an environment where the temperature gradually rises, and observing warping changes of the sample; and step 4, when the warping of the sample returns to zero, recording the current temperature of the sample, and calculating the curing shrinkage rate of the adhesive. The method achieves the measurement of the curing shrinkage rate of the adhesive, is simple, and is suitable for the measurement of curing shrinkage rates under the adhesive working conditions of different sizes, different materials, different interface states, etc.

Classes IPC  ?

• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
• G01N 33/44 - RésinesMatières plastiquesCaoutchoucCuir

Abrégé

The present invention relates to the field of biopharmaceuticals, and in particular, to an ultrasound contrast agent, a method for preparing same, and use thereof. An antibody targeting the prostate-specific membrane antigen is covalently linked to the surface of a biological protein nanobubble for the first time, and an ultrasonic molecular probe using a gas vesicle as the carrier and targeting the prostate-specific membrane antigen is obtained. The present invention improves the imaging performance and the tumor targeting property of the ultrasound contrast agent, features a simplified preparation process, and aids in early drug development, precision diagnosis, and precision treatment of tumors such as prostate cancer.

Classes IPC  ?

• A61K 49/22 - Préparations pour échographiePréparations pour imagerie par ultrasons

Abrégé

A method and apparatus for reconstructing a magnetic resonance image, and a device and a medium. The method comprises: acquiring magnetic resonance undersampled k-space data of a target region of interest, and inputting the magnetic resonance undersampled k-space data into a pre-trained self-supervised magnetic resonance image reconstruction model, so as to obtain the mapping between the magnetic resonance undersampled k-space data and a target magnetic resonance image and the distribution of network parameters corresponding to the self-supervised magnetic resonance image reconstruction model (S110); inputting the mapping and the distribution of the network parameters into a score-matching network constructed on the basis of a distribution feature of the network parameters corresponding to the self-supervised magnetic resonance image reconstruction model, so as to obtain the score of a target data distribution feature corresponding to the target magnetic resonance image (S120); and on the basis of the score of the target data distribution feature, reconstructing the magnetic resonance undersampled k-space data by means of preset Langevin Markov chain Monte Carlo sampling, so as to obtain a target magnetic resonance reconstructed image (S130).

Classes IPC  ?

• G06T 11/00 - Génération d'images bidimensionnelles [2D]

Abrégé

The use of an attenuated herpes simplex virus in the preparation of a neural circuit retrograde tracing tool virus. The attenuated herpes simplex virus is prepared on the basis of a targeting vector, wherein the targeting vector is a vector in which a complete fluorescent protein gene or other exogenous target gene expression cassette is inserted between the upstream and downstream homologous arms of the neurovirulence factor γ34.5 gene of the vector pH129ΔRL1. It is found for the first time that the ltHSV-hUbC-tdT-WPRE virus can be used for neural circuit retrograde tracing, and that the virus enables efficient axonal terminal infection to label the upstream regulatory brain regions of the target brain region in a retrograde manner. Moreover, for up to two months of labeling, cell body signals can be observed only in the upstream brain regions that can directly project to the target brain region, without exhibiting anterograde transsynaptic spread. Therefore, the virus can be used as a new tracing virus system with a relatively stringent retrograde labeling ability and a broader spectrum of neural tropism.

Classes IPC  ?

• C12N 7/01 - Virus, p. ex. bactériophages, modifiés par l'introduction de matériel génétique étranger
• C12N 15/869 - Vecteurs herpèsviraux
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
• C12R 1/93 - Virus des animaux
• G01N 1/42 - Traitement à basse température des échantillons, p. ex. cryofixation

Abrégé

The present application relates to the technical field of computers. Provided are a method and apparatus for generating a medical three-dimensional model, and an electronic device and a storage medium. The method for generating a medical three-dimensional model comprises: in response to an input operation in an interactive interface, acquiring medical text; calling a first generative network, and under the guidance of the medical text, learning a first tensor inputted into the first generative network, so as to obtain a medical two-dimensional image conforming to the description in the medical text, wherein the first generative network is a deep learning model which has been trained and has the capability of generating a medical two-dimensional image from medical text; inputting the medical two-dimensional image into a second generative network to generate a medical three-dimensional model, wherein the second generative network is a deep learning model which has been trained and has the capability of generating a medical three-dimensional model from a medical two-dimensional image; and displaying in the interactive interface the medical three-dimensional model generated by the second generative network. The present application solves the problem in the prior art of the poor fidelity of medical three-dimensional models.

Classes IPC  ?

• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
• G06T 11/60 - Édition de figures et de texteCombinaison de figures ou de texte
• G06T 11/00 - Génération d'images bidimensionnelles [2D]

Abrégé

The present application proposes an electroacupuncture-visual stimulation combined analgesia apparatus, comprising an electroacupuncture module and a visual stimulation module which are in a working state at the same time. The combined application of electroacupuncture and visual stimulation can be achieved. By means of the combined therapy, in the acupuncture process, a patient is less likely to experience nervousness, resulting in a positive influence on the pain perception or mental state, so that the therapeutic effect can be improved. In addition, the present application adopts looming stimulation and applies multiple sets of visual stimulation, such that a better therapeutic effect can be achieved by means of the relatively high visual stimulation intensity and repeated visual stimulation. Moreover, the therapeutic apparatus of the present application is flexible and convenient to use, can be flexibly used according to a required treatment site, and has wide application prospects.

Classes IPC  ?

• A61H 39/00 - Dispositifs de physiothérapie pour localiser ou stimuler les endroits spécifiques de réflexe du corps, p. ex. acupuncture
• A61H 39/08 - Dispositifs pour placer des aiguilles auxdits endroits, c.-à-d. pour l'acupuncture
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/34 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour provoquer l'anesthésie
• A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose
• A61M 21/02 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose pour provoquer le sommeil ou la relaxation, p. ex. par stimulation directe des nerfs, par hypnose ou par analgésie

Abrégé

The present application provides an electroacupuncture and visual stimulation combination attention improvement device, comprising an electroacupuncture module and a visual stimulation module that operate simultaneously to apply electroacupuncture and visual stimuli in combination. By means of a combination of treatment modalities, in the acupuncturing process, the device is less likely to make the patient nervous and may provide a positive influence on the mental state of the patient, thus improving the therapeutic effect. In addition, looming stimulation is adopted in the present application, and multiple sets of visual stimuli are applied, so as to achieve a better treatment effect by means of strong visual stimulation and repeated visual stimuli. Moreover, the treatment device of the present application features flexibility and convenience for use in different body parts to be treated, and thus possesses broad application prospects.

Classes IPC  ?

• A61H 39/00 - Dispositifs de physiothérapie pour localiser ou stimuler les endroits spécifiques de réflexe du corps, p. ex. acupuncture
• A61H 39/08 - Dispositifs pour placer des aiguilles auxdits endroits, c.-à-d. pour l'acupuncture
• A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques

Abrégé

The present invention relates to the technical field of ethology, and in particular relates to a multi-view synchronous behavior capture method and system, and an electronic device. The method comprises: creating a control process, and creating an acquisition process and a compression process for each camera; each camera capturing a frame of image data; sending the image data to the corresponding acquisition process, which then sends the image data to the corresponding compression process, incrementing a semaphore in the control process by a value equal to the number of acquisition processes that have received images, and blocking the corresponding acquisition processes; determining whether the semaphore acquired in the control process is greater than or equal to the total number of cameras, and if so, proceeding to the next step, and if not, repeating the previous step; determining whether the number of frames acquired in each acquisition process is equal to a preset number, and if so, completing capture, and if not, awakening the acquisition processes and repeating the previous three steps. By means of the described configuration, the present invention remedies the defect of existing multi-view cameras being prone to frame loss during biological behavior acquisition.

Classes IPC  ?

• G06V 10/10 - Acquisition d’images
• H04N 23/60 - Commande des caméras ou des modules de caméras
• G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
• G06V 10/94 - Architectures logicielles ou matérielles spécialement adaptées à la compréhension d’images ou de vidéos
• G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes
• G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c.-à-d. étalonnage de caméra
• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie

Abrégé

Provided is a construction method for a modular orthogonal high-performance transcription factor DNA-binding domain (DBD) system, comprising the following steps: S1, selecting a basic architecture of a modular transcription factor and a basic architecture of a corresponding regulatory promoter; S2, on the basis of the basic architecture of the transcription factor and the basic architecture of the regulatory promoter, constructing a standard test vector containing a lethal gene CCDB, and constructing paired DBD-operator test plasmids; and S3, constructing a standard test system, testing regulatory fold-changes of different strain transcription factor DBD-operators, selecting transcription factor DBD-operators capable of high-performance transcription to perform an orthogonality test, and obtaining transcription factor DBD-operators which are mutually orthogonal and capable of high-performance transcription regulation. According to the construction method, modular DBD-operators are tested and screened to finally obtain DBD-operators which are mutually orthogonal and capable of high-performance transcription regulation.

Classes IPC  ?

• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
• C12N 15/31 - Gènes codant pour des protéines microbiennes, p. ex. entérotoxines
• C12N 15/65 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression utilisant des marqueurs
• C12Q 1/06 - Détermination quantitative
• C12R 1/19 - Escherichia coli
• C12R 1/865 - Saccharomyces cerevisiae

Abrégé

The present invention provides a modular orthogonal eukaryotic transcription factor model construction method, comprising the following steps: S1, establishing the basic architecture DBD-LBD-AD of a transcription factor; S2, constructing a domain screening vector and system to screen effective DBD, LBD and AD; S3, screening out corresponding parameters of each DBD and LBD domain; S4, on the basis of the corresponding parameters of each DBD and LBD domain, characterizing a transcription factor regulation process, and establishing a quantitative model of transcription regulation; predicting the transcription factor under conditions of different DBD and LBD combinations by means of the quantitative model of transcription regulation, to obtain a transcription factor having optimized performance. The modular orthogonal eukaryotic transcription factor model construction method of the present invention, by means of determining the basic architecture of a modular transcription factor, ultimately establishes a quantitative model of transcription regulation, achieving modular domain parameter optimization of the transcription factor, and obtaining a transcription factor having optimized performance.

Classes IPC  ?

• G16B 5/00 - TIC spécialement adaptées à la modélisation ou aux simulations dans la biologie des systèmes, p. ex. réseaux de régulation génétique, réseaux d’interaction entre protéines ou réseaux métaboliques
• C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures

Abrégé

The present invention relates to the field of medical experimental animal model technology, and in particular, to an animal experiment model and method for calcium signal recording. The model comprises: introducing a fluorescent marker into neurons of a target subject from a selected specific area of the target subject, arranging a microscope camera fixing seat at the specific area of the target subject, and using a microscope camera to observe the brain activity of the target subject. The present invention achieves the construction of the animal model for intravenous administration and calcium signal recording, and the drug action and treatment mechanisms can be conveniently explored by observing the change of the calcium signal at the instant of intravenous infusion of the drug.

Classes IPC  ?

• A61D 1/00 - Instruments de chirurgie vétérinaire
• A61D 7/00 - Dispositifs ou méthodes pour l'introduction de remèdes, solides, liquides ou gazeux ou d'autres produits dans ou sur le corps des animaux
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Provided are a recombinant bacmid preparation system and a BmNPV-recombinant adeno-associated virus (rAAV) recombinant bacmid. The recombinant bacmid preparation system comprises: a) DH10pureBac competent cells containing a loss-controllable helper plasmid and a modified baculovirus genome, and b) a loss-controllable transfer vector. The BmNPV-rAAV recombinant bacmid is a single BmNPV bacmid containing an rAAV Cap gene expression cassette, a core expression element ITR-GOI, and a Rep gene expression cassette. The present application solves the problem of residual helper plasmids and transfer vectors in a Bac-to-Bac baculovirus expression system and involves a simple technique process.

Classes IPC  ?

• C12N 15/866 - Vecteurs baculoviraux
• C12N 15/09 - Technologie d'ADN recombinant

Abrégé

Disclosed in the present invention are a method for preparing a transfer vector pAAV-Donor in a baculovirus-rAAV production system and the use. The preparation method comprises: removing type IIS restriction enzyme recognition sites from an AAV Cap gene expression cassette by means of mutation; modifying the obtained AAV Cap gene expression cassette; preparing AAV-Core, AAV-Cap and AAV-Rep backbone plasmids; sequentially inserting the modified Cap gene expression cassette, a heterologous functional gene expression element and the modified AAVRep gene expression cassette into the multiple cloning sites of the AAV-Cap, AAV-Core and AAV-Rep backbone plasmids to obtain pAAV-Rep, pAAV-Cap and pAAV-Core; and assembling the three plasmids in one step by means of the Golden Gate cloning technology, transforming same into Stbl3 competent cells, and screening positive clones to obtain pAAV-Donor.

Classes IPC  ?

• C12N 15/866 - Vecteurs baculoviraux
• C12N 15/864 - Vecteurs parvoviraux
• C12N 7/01 - Virus, p. ex. bactériophages, modifiés par l'introduction de matériel génétique étranger
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus

Abrégé

The present disclosure provides a value set extraction method, a cell differentiation method, an identification method, a device, and a medium. The value set extraction method comprises: sorting genes of a single cell, then grouping the genes to obtain a plurality of gene combinations, and using each gene combination as a chromatin unwinding segment; selecting the transcription level of one gene, one gene combination or a plurality of gene combinations to construct a baseline value set of the single cell; constructing a value set of each gene combination on the basis of the transcription level of each gene combination; for each gene combination, comparing the baseline value set with the value set of the gene combination to obtain the value of the gene combination chromatin unwinding segment; and determining a value set of the chromatin unwinding segment of the single cell on the basis of the value of the gene combination chromatin unwinding segment.

Classes IPC  ?

• G06F 18/241 - Techniques de classification relatives au modèle de classification, p. ex. approches paramétriques ou non paramétriques

Abrégé

The present invention relates to the field of solar cells, and in particular to a rubidium and cesium co-doped wide-band-gap perovskite material and a preparation method therefor, and a rubidium and cesium co-doped high-open-circuit-voltage solar cell. The crystal growth kinetics of a wide-band-gap perovskite thin film is regulated and controlled by means of rubidium and cesium co-doping, so that the defect density of the perovskite material is greatly reduced, the non-radiative recombination of a wide-band-gap perovskite solar cell is effectively suppressed, the loss of open-circuit voltage is reduced, and the efficiency of the wide-band-gap perovskite solar cell is improved.

Classes IPC  ?

• H10K 85/50 - Pérovskites organiquesPérovskites hybrides organiques-inorganiques [HOIP], p. ex. CH3NH3PbI3
• H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
• H10K 30/50 - Dispositifs photovoltaïques [PV]

Abrégé

Provided is a micro- and nano-fluidic chip, including at least one nanochannel array layer and at least one microchannel array layer that are alternately stacked. The at least one nanochannel array layer includes nanochannels, the at least one microchannel array layer includes input units and/or output units. The input unit includes inlet microchannel arrays and inlets, and the output unit includes outlet microchannel arrays and outlets. The inlet microchannel array includes inlet microchannels, the outlet microchannel array includes outlet microchannels, and the inlet microchannels and the outlet microchannels are connected through the nanochannels.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• G03F 7/038 - Composés macromoléculaires rendus insolubles ou sélectivement mouillables
• G03F 7/039 - Composés macromoléculaires photodégradables, p. ex. réserves positives sensibles aux électrons
• G03F 7/20 - ExpositionAppareillages à cet effet
• G03F 7/32 - Compositions liquides à cet effet, p. ex. développateurs
• G03F 7/38 - Traitement avant le dépouillement selon l'image, p. ex. préchauffage
• G03F 7/40 - Traitement après le dépouillement selon l'image, p. ex. émaillage

Abrégé

Provided is a micro- and nano-fluidic chip, including at least one nanochannel array layer and at least one microchannel array layer that are alternately stacked. The at least one nanochannel array layer includes nanochannels, the at least one microchannel array layer includes input units and/or output units. The input unit includes inlet microchannel arrays and inlets, and the output unit includes outlet microchannel arrays and outlets. The inlet microchannel array includes inlet microchannels, the outlet microchannel array includes outlet microchannels, and the inlet microchannels and the outlet microchannels are connected through the nanochannels.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• G03F 7/038 - Composés macromoléculaires rendus insolubles ou sélectivement mouillables
• G03F 7/039 - Composés macromoléculaires photodégradables, p. ex. réserves positives sensibles aux électrons
• G03F 7/20 - ExpositionAppareillages à cet effet
• G03F 7/32 - Compositions liquides à cet effet, p. ex. développateurs
• G03F 7/38 - Traitement avant le dépouillement selon l'image, p. ex. préchauffage
• G03F 7/40 - Traitement après le dépouillement selon l'image, p. ex. émaillage

Abrégé

Disclosed in the present invention is a method for enhancing a biomolecular condensate targeting function of a drug by means of charge modification. The method comprises the following steps: (1) determining the electrostatic potential range of a condensate that is formed by or enriched by, in vitro or intracellularly, a target biomolecule associated with a disease; and (2) carrying out a charge modification on a drug with a known target, the drug with the known target being a drug having a prevention and/or treatment effect on the disease described in step (1), the modified drug with the known target and the condensate carrying opposite net charges, so that the targeting specificity of the drug with the known target after the charge modification can be enhanced. The present invention performs charge modification on a drug with a known target on the basis of the electric potential of a target biomolecular condensate, and adds a functional group or amino acid carrying net charges that are opposite to that of the target biomolecular condensate, so as to enhance the targeting specificity of the drug with the known target, thereby improving the treatment effect of the drug.

Classes IPC  ?

• A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
• G01N 21/64 - FluorescencePhosphorescence

Abrégé

Embodiments of the present application relate to the technical fields of AI and digital healthcare, and provide a lung-brain image processing method and apparatus, a device, and a storage medium. The method comprises: collecting medical image data and clinical feature data, wherein the medical image data comprises lung images and brain images, and the medical image data is obtained on the basis of positron emission tomography-computed tomography; screening for target clinical features from the clinical feature data; preprocessing the lung images to obtain a lung preliminary image; preprocessing the brain images to obtain a brain preliminary image; performing deep and shallow feature extraction on the lung preliminary image to obtain lung deep features and lung shallow features, and performing deep feature extraction on the brain preliminary image to obtain brain deep features; performing feature screening on the target clinical features, the lung deep features, the lung shallow features, and the brain deep features to obtain target features; and performing disease classification on the basis of the target features to obtain a target disease category. The embodiments of the present application can improve the accuracy and efficiency of disease classification.

Classes IPC  ?

• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients

Abrégé

A mass spectrometry injection system and method for automatic microcell analysis, relating to the technical field of mass spectrometry. In the system, a cell suction device suctions cells in a cell suspension by using a suction needle (11) to obtain microcells; then a motion device (4) is used to clamp the suction needle (11) containing the cells from an opening into an electrical lysis cavity, and an electrical lysis device (2) is used for electrical lysis of the cells in the suction needle (11) to obtain intracellular substances; next, the motion device (4) is used to clamp the suction needle (11) to the position of a mass spectrometry injection interface. An electrospray induction device comprises the suction needle (11) and a steel tube sleeved outside the suction needle (11), and a voltage is applied to the steel tube by means of a first power supply unit, so that the cellular substances in the suction needle (11) generate electrospray, thereby implementing injection processing at the mass spectrometry injection interface. According to the system, by using a fully-automatic processing mode, the whole process from cell separation to lysis to mass spectrometry injection can be efficiently and quickly completed, the detection time is shortened, manual operation is avoided, and reliable repeatability and precision are achieved.

Classes IPC  ?

• G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection
• G01N 15/1031 - Recherche de particules individuelles en mesurant des effets électriques ou magnétiques
• G01N 27/62 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'ionisation des gaz, p. ex. des aérosolsRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant les décharges électriques, p. ex. l'émission cathodique

Abrégé

The present application relates to the technical field of DNA storage. Provided are a method and apparatus for encryption and coding during DNA storage, and an electronic device and a storage medium. The method for encryption and coding comprises: acquiring data to be stored, and a first random number sequence and a second random number sequence which are generated by a hyperchaotic pseudo-random sequence generator; using the first random number sequence to encrypt the data to be stored, so as to obtain source data; performing DNA Raptor coding on the source data, and introducing the second random number sequence into a DNA Raptor coding process as a random number seed, so as to obtain at least one piece of coded data; and on the basis of a DNA base mapping rule, converting each piece of coded data into a corresponding DNA sequence, and generating a target DNA sequence from the DNA sequence corresponding to each piece of coded data. The present application solves the problem in the related art of data security being not taken into consideration during DNA storage.

Classes IPC  ?

• H04L 9/00 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité
• H04L 9/08 - Répartition de clés

Abrégé

The present application provides a butt joint mechanism, and a combination of a medical mechanical arm and an operation bed. The butt joint mechanism comprises : a suspension mechanism, a guide column, a guide sleeve, a locker, and a locking sleeve, wherein one of the guide column and the guide sleeve is installed on a component A, and the other one of the guide column and the guide sleeve is installed on a component B, and by means of cooperation of the guide column and the guide sleeve, connection between the component A and the component B is guided, such that butt joint between the locker and the locking sleeve is assisted. One of the locker and the locking sleeve is installed on the component A, the other one of the locker and the locking sleeve is installed on the component B, and by means of cooperation of the locker and the locking sleeve, the component A and the component B can be connected together. The suspension mechanism is installed on the component A or the component B, the suspension mechanism enables the component A or the component B to float up and down relative to the ground, and then the relative position between the guide column and the guide sleeve, and the relative position between the locker and the locking sleeve can be adjusted, such that butt joint between the component A and the component B is facilitated; and in addition, the floating degree can be adjusted by the suspension mechanism.

Classes IPC  ?

• A61B 34/30 - Robots chirurgicaux

Abrégé

The present application relates to the technical field of image processing, and provides a pose estimation method and apparatus, an electronic device, and a storage medium. The method comprises: acquiring an image to be recognized, said image being a three-dimensional image obtained by photographing a target to be recognized; constructing a target function on the basis of geometric features of said target in the image to be recognized; and calling a pose estimation model, and, on the basis of the target function, performing pose estimation on the image to be recognized, to obtain a pose estimation result corresponding to said target. The present application solves the problem in the related art of low pose estimation accuracy.

Classes IPC  ?

• G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
• G06T 7/60 - Analyse des attributs géométriques
• G06N 5/01 - Techniques de recherche dynamiqueHeuristiquesArbres dynamiquesSéparation et évaluation
• G06N 20/00 - Apprentissage automatique

Abrégé

The present application provides a fluorescent dye, and a preparation method therefor and a use thereof. The fluorescent dye has a structure as shown in formula I, is a silicon-based Rhodamine organic dye, has excellent near-infrared fluorescence characteristics, and contains a conjugated ligand group R in the molecular structure, so that the fluorescent dye can coordinate with various transition metals, thereby improving the response between the metals and the silicon-based Rhodamine dye, and an obtained metal complex can fully exert the characteristics of the complex and the characteristics of silicon-based Rhodamine near-infrared light absorption and emission. The fluorescent dye and the metal complex containing same can be used in the fields of photosensitizers, cell staining, photocatalysis, photodynamic therapy and the like, and have wide application prospects. The preparation method for the fluorescent dye provided by the present application is simple, has mild reaction conditions, is suitable for large-scale preparation, has a high yield and few by-products, is easy to purify to obtain pure products, and greatly widens the application range of silicon-based Rhodamine dyes.

Classes IPC  ?

• C07F 7/10 - Composés comportant une ou plusieurs liaisons C—Si azotés
• C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
• C09B 57/00 - Autres colorants synthétiques de structure connue
• H10K 85/40 - Composés organosiliciés, p. ex. pentacène TIPS
• B01J 35/39 - Propriétés photocatalytiques
• H10K 85/30 - Composés de coordination
• B01J 31/2 -
• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire

Abrégé

An Alzheimer's disease biomarker based on a brain metabolite and a use thereof. The biomarker comprises any one or a combination of at least two of palmitic acid, DHA, gallic acid, 11Z,14Z,17Z-eicosatrienoic acid, glycodeoxycholic acid, palmitoleic acid, linoleic acid, erucic acid, petroselinic acid, and arachidonic acid. The level of a metabolite is detected to assist in early diagnosis of the Alzheimer's disease, thus facilitating rapid detection; in addition, the present invention has the characteristics of timeliness, convenience, high specificity and high sensitivity.

Classes IPC  ?

• G01N 30/02 - Chromatographie sur colonne
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

Provided in the present application is the use of an Alzheimer's-disease intestinal flora biomarker combination in the preparation of a product for detecting AD. The marker combination comprises: any one of or a combination of at least two of Akkermansia muciniphila, Turicibacter, Dubosiella, Pantoea, Alistipes, Lactobacillus, Erysipelothrix, Lachnospira, Enterobacter, Corynebacterium, Clostridium, an undefined genus in Erysipelotrichaceae, Brevibacterium or Odoribacter. In the present invention, the abundance level of the intestinal flora biomarker combination is used as a detection index for early auxiliary diagnosis of Alzheimer's disease.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
• C12Q 1/6869 - Méthodes de séquençage
• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• C12R 1/145 - Clostridium
• C12R 1/225 - Lactobacillus
• C12R 1/01 - Bactéries ou actinomycètes

Abrégé

A graphene neural electrode, a preparation method therefor, and use thereof. The preparation method comprises the following steps: (1) performing laser printing on a polyimide film according to a preset electrode pattern to obtain laser-induced graphene; (2) subjecting the laser-induced graphene to transfer printing to a water-soluble adhesive tape, then arranging a thermoplastic polymer thin film on one side of the laser-induced graphene away from the water-soluble adhesive tape, and then removing the water-soluble adhesive tape, so that the laser-induced graphene is subjected to transfer printing to the thermoplastic polymer thin film to obtain a first prefabricated product; (3) placing the first prefabricated product in a conductive polymer monomer solution for electrochemical polymerization, and forming a conductive polymer layer to obtain a second prefabricated product; and (4) arranging a thermoplastic polymer packaging layer on the conductive polymer layer of the second prefabricated product to obtain the graphene neural electrode. The graphene neural electrode prepared by using the method has excellent flexible characteristics and mechanical properties, high mechanical and electrochemical stability, and low electrochemical impedance, thereby achieving long-term stable signal monitoring in an organism.

Classes IPC  ?

• A61B 5/268 - Électrodes bioélectriques à cet effet caractérisées par les matériaux des électrodes contenant des polymères conducteurs, p. ex. des polymères PEDOT:PSS
• G01N 27/327 - Électrodes biochimiques

Abrégé

A super-resolution microscope objective, a manufacturing method and a super-resolution microscopic device. A plano-convex lens (16) is manufactured on a glass sheet in a controllable preparation mode; then by means of precise micro-control and thermal/light curing, a microsphere (22) is controllably positioned and fixed on the upper surface of the central position of the plano-convex lens (16); and the glass sheet is integrated with a sleeve and mounted on an objective lens (27) to form a microsphere (22) assisted super-resolution microscope objective. According to the super-resolution microscope objective provided, water or oil is added above the glass sheet, and thus would not contact with a sample and has no potential pollution or impact; compared with other methods of directly placing the microsphere (22) on a plane or a flat plate, placing the microsphere (22) on the plano-convex lens (16) can effectively avoid the problem that during microsphere (22) assisted imaging, the other positions of the objective lens contact with the sample earlier, so that the microsphere (22) cannot achieve imaging; and the plano-convex lens (16) can be adjusted according to requirements, and the plano-convex lens (16) has certain enhancement effect on the imaging effect of the microsphere (22). In addition, the manufacturing method is simple and easy to control and can be easily operated and implemented, and the performance of a conventional optical microscope can be improved at low cost.

Classes IPC  ?

• G02B 21/02 - Objectifs
• G02B 27/58 - Optique pour l'apodisation ou la super-résolvanceSystèmes optiques à ouverture synthétisée

Abrégé

A super-resolution imaging system and a super-resolution imaging method. A microsphere lens assembly (2) is fixed on a sleeve (1). The microsphere lens assembly (2) comprises a glass sheet (21), a plano-convex lens (22) located at the central position of the glass sheet (21), and a microsphere (23) located at the top end of the plano-convex lens (22). A transparent polymer is arranged between the microsphere (23) and the plano-convex lens (22). The sleeve (1) is fixed on an objective lens (15) to form a super-resolution objective lens, and the super-resolution objective lens is combined with a conventional optical microscope to construct a super-resolution imaging method and system based on microsphere lens assistance, so that real-time, rapid and label-free imaging can be achieved for samples below a diffraction limit scale, the manufacturing process is simple, convenient and rapid and has low costs, and the microsphere lens assisted super-resolution imaging technology is expected to be pushed to further develop towards practical applications. In addition, the microsphere lens is integrated on the objective lens by means of the sleeve to perform super-resolution imaging, thereby constructing a super-resolution imaging method and system which have low complexity and good adjustability, can block the effect of an immersion liquid in a water/oil immersion objective on samples, and achieve controllable positioning of an imaging area.

Classes IPC  ?

• G02B 21/26 - PlatinesMoyens de réglage pour celles-ci

Abrégé

Provided are an implant, a manufacturing method therefor, and the use thereof. The implant comprises a material body, a metal oxide layer and a mixed crystalline layer, the mixed crystalline layer being provided on a surface of the metal oxide layer. The metal oxide layer comprises a metal oxide nanorod array, the metal oxide being selected from zinc oxide, silver oxide or a combination thereof. The mixed crystalline layer comprises a CaP crystal and a metal oxide crystal. The implant uses the physical puncturing of the metal oxide nanorods and antibacterial metal ions generated by degradation of same for sterilization, and has good antibacterial effect on both gram-positive bacteria and gram-negative bacteria, thereby preventing infections; and the implant can relieve post-implantation inflammatory responses and reduce immune responses in the case of post-implantation infections, thereby shortening the time for wound healing. In addition, the coating effect of the mixed crystalline layer on the metal oxide layer enables sustained release of the antibacterial metal ions and enables the release time to be long, thus achieving long-lasting antibacterial performance.

Classes IPC  ?

• A61L 27/30 - Matériaux inorganiques
• A61L 27/06 - Titane ou alliages de titane
• A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

Embodiments of the present application relate to the technical field of medical image processing, and provide a medical image recognition method and apparatus, a device and a storage medium. The method comprises: acquiring a target image set, the target image set comprising a plurality of target whole-body tomographic images collected in a first preset time sequence; extracting organ tomographic images of a target organ from the target whole-body tomographic images; constructing an initial organ matrix for the target organ tomographic images of each target whole-body tomographic image; calculating a metabolic reference matrix and the initial organ matrix on the basis of a preset object metabolic difference sub-network, to obtain an organ metabolic difference matrix; and performing metabolic difference recognition on the basis of the organ metabolic difference matrix and the metabolic reference matrix, to obtain a target metabolic difference map that represents metabolic difference information between any two target organs in the target whole-body tomographic images. The embodiments of the present application can improve the recognition accuracy of images acquired by positron emission tomography, thereby improving the accuracy of determining metabolic conditions of individual objects.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• G06T 7/11 - Découpage basé sur les zones

Abrégé

Disclosed in the present invention are a drug for treating or preventing methamphetamine addiction, and the use. Also disclosed is a new use of an ERK inhibitor. In the present invention, the use of an ERK inhibitor in drug addiction is studied. The inhibitory effect of GDC-0994 in the treatment of methamphetamine addiction is studied by means of methamphetamine addiction models (including a place preference model and a self-administration experiment model), and it is found that the administration of the ERK inhibitor GDC-0994 can significantly reduce the seeking and ingesting of methamphetamine in animals, that is, the ERK inhibitor GDC-0994 can antagonize methamphetamine addiction, this indicates that the inhibition of ERK by GDC-0994 can effectively treat methamphetamine addiction.

Classes IPC  ?

• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61P 25/30 - Médicaments pour le traitement des troubles du système nerveux des états d'abus ou de dépendance

Abrégé

The embodiments of the present description relate to the technical field of data processing, and in particular to a cross-shard transaction processing method and system. The method comprises: after receiving the current Epoch number and a cross-shard transaction corresponding thereto which are sent by a cross-shard service module, each shard node processes the cross-shard transaction; and each shard node determines whether a respective received second transaction sent by a client belongs to a local transaction type of the shard node itself and, if so, processes same or, if not, sends to the cross-shard service module the second transaction as a non-local transaction. The embodiments of the present description solve the problems of existing cross-shard transaction processing technologies that centralized serial sorting results in relatively high sorting costs, and failure to distinguish between intra-shard transactions and cross-shard transactions results in a waste of communication resources.

Classes IPC  ?

• H04L 67/1074 - Réseaux de pairs [P2P] pour la prise en charge des mécanismes de transmission de blocs de données

Abrégé

Provided are a magnetically controllable liquid embolization robot and a magnetic control embolization system, which belong to the field of medical instruments. The magnetically controllable liquid embolization robot uses a pure liquid embolization technology; a mixed liquid of an embolization material and magnetic powder particles exists in vitro; in use, the mixed liquid is injected into an in-vivo blood environment and fixed to a target part by means of magnetic control, or flows in a complex zigzag blood vessel to the target part and is fixed by means of magnetic control; and the mixed liquid has an ion cross-linking reaction in the blood environment, and is completely solidified into a gel-state at the target part so as to complete embolization. The robot can resist blood flow impact, does not need an additional device for blockage in the whole operation process, breaks through an existing solid embolization and solid-liquid combined embolization technology, and is safe and flexible.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
• A61L 24/06 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons carbone-carbone non saturées
• A61L 24/00 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie
• A61L 24/02 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux inorganiques
• A61L 24/12 - Ciments d'ionomères, p. ex. ciments verre-ionomère

Abrégé

Embodiments of the present application provide a method for fabricating an electromyographic/acoustomyographic bimodal stretchable device. The method comprises: S1, fabricating a flexible stretchable electromyographic sensor using silica gel as the substrate and gold as the stretchable conductive material by means of thermal evaporation; and S2, integrating, on the basis of the fabricated flexible stretchable electromyographic sensor, a microphone with a multi-channel electromyographic electrode of the flexible stretchable electromyographic sensor by means of localized hardening and liquid metal connection, so as to complete the fabrication of the electromyographic/acoustomyographic bimodal stretchable device. The electromyographic electrode involved in the scheme of the present invention features flexibility and stretchability and is conformally adaptive to the skin to conduct stable electrophysiological signal monitoring. The involved device is flexible, stretchable, and conformally adaptive to the skin, so as to conduct stable in-situ synchronous monitoring of electromyographic and acoustomyographic bimodal signals.

Classes IPC  ?

• A61B 5/296 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électromyographie [EMG]
• A61B 5/394 - Électromyographie [EMG] spécialement adaptée pour l’électroglottographie ou l’électropalatographie
• A61B 5/268 - Électrodes bioélectriques à cet effet caractérisées par les matériaux des électrodes contenant des polymères conducteurs, p. ex. des polymères PEDOT:PSS

Abrégé

Disclosed in the present application is a method for controlling an output air pressure, which belongs to the technical field of medical instruments. A pipeline structure for controlling the output air pressure of the present application comprises a pipeline body and an air supply apparatus. The pipeline body comprises a plurality of pipeline assemblies. The plurality of pipeline assemblies are movably connected by means of preset connecting members. The air supply apparatus is configured for introducing gas into the pipeline body. One end of the pipeline body is connected to the air supply apparatus. The other end of the pipeline body is in communication with the atmosphere. Each of the pipeline assemblies comprises a pipeline element and a pipeline interface. The pipeline interface is configured to be connected to an actuator for outputting the air pressure for a robot part.

Classes IPC  ?

• A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
• F17D 3/01 - Dispositions pour la surveillance ou la commande des opérations de fonctionnement pour commander, signaler ou surveiller le transfert d'un produit

Abrégé

Embodiments of the present application provide a behavior analysis method and apparatus, a network device and a storage medium. The method comprises: on the basis of N camera assemblies at different positions, acquiring N pieces of video data of a first target object and a second target object, and extracting N video frames having the same acquisition time as a data group, wherein N is greater than or equal to 4; performing instance segmentation on the first target object and the second target object in the video frames in the data group, and when single-object cropping has been performed, determining a first image group corresponding to the first target object and a second image group corresponding to the second target object; tracking first key points of the first target object on the basis of the first image group to determine first spatial posture information; and tracking second key points of the second target object on the basis of the second image group to determine second spatial posture information; and determining a behavior analysis result of the first target object and the second target object on the basis of the first spatial posture information and the second spatial posture information.

Classes IPC  ?

• G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes

Abrégé

Embodiments of the present application relate to the field of computer vision. Disclosed are a target six-degree-of-freedom pose estimation method and apparatus based on binocular vision and particle swarm optimization. The method comprises: obtaining a binocular image of a target, wherein the binocular image at least comprises a rotation matrix, a displacement vector and geometric features of the target; decomposing the rotation matrix into a rotation vector and a rotation angle by means of a rotation matrix decomposition method, and performing six-degree-of-freedom uniform sampling on the rotation vector and the rotation angle to obtain a data point set; establishing a mathematical relationship between the rotation matrix and the displacement vector on the basis of the geometric property of the geometric features and the data point set; and performing target pose estimation on the binocular image of the target by designing an objective function and an application optimization algorithm to obtain a pose estimation result. The present application solves the problems in the related art of low accuracy, poor universality and poor robustness.

Classes IPC  ?

• G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques

Abrégé

Provided are a consciousness state detection system and method, wherein the system comprises: a visual stimulation apparatus (110) arranged in a visual field region of a target subject and configured for displaying visual stimulation information so as to perform, on the basis of the visual stimulation information, visual stimulation on the target subject (S310), wherein the visual stimulation information comprises visual field shadow stimulation and/or visual threat stimulation; a feedback behavior collection apparatus (120) connected to a consciousness state determination apparatus (130) and configured for collecting, when the visual stimulation information is displayed, a target feedback behavior of the target subject and sending the target feedback behavior to the consciousness state determination apparatus (S320); and the consciousness state determination apparatus (130), which is configured for receiving the target feedback behavior sent by the feedback behavior collection apparatus (120), and determining, on the basis of the target feedback behavior and a standard feedback behavior, the consciousness state of the target subject (S330). By adopting the technical solutions of the present invention, the consciousness state of the target subject can be quickly, conveniently, and accurately determined.

Classes IPC  ?

• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/378 - Stimuli visuels

Abrégé

The present invention relates to a decoding method for predicting response information on the basis of response data of a cell to an external dynamic signal. The decoding method of the present invention formalizes a dynamic signal recognition problem into a classification task, uses simulation data samples to train a model, and then uses the trained model to predict and determine dynamic response data in a real experiment, so as to acquire response information of a dynamic signal. The present invention uses a machine learning method to predict and determine dynamic response data of cells, so as to provide deeper insights for researchers, helping the researchers understand how cells extract information from environments and make adaptive responses.

Classes IPC  ?

• G06F 18/2411 - Techniques de classification relatives au modèle de classification, p. ex. approches paramétriques ou non paramétriques basées sur la proximité d’une surface de décision, p. ex. machines à vecteurs de support
• G06F 18/27 - Régression, p. ex. régression linéaire ou logistique
• G06N 20/10 - Apprentissage automatique utilisant des méthodes à noyaux, p. ex. séparateurs à vaste marge [SVM]
• G16B 40/20 - Analyse de données supervisée

Abrégé

The present application relates to the technical field of DNA encryption, and discloses a DNA encryption method and apparatus based on randomly combined code tables, a device, and a storage medium. The method comprises: obtaining seven designed code tables of different sizes and a file to be encoded; generating a random number on the basis of the file type of said file, selecting a code table among the code tables on the basis of the random number, and using the selected code table as a target code table; performing encoding conversion on the basis of the target code table and said file to obtain a DNA encoding result, and on the basis of the length corresponding to the DNA encoding result, using chaotic mapping to generate a random sequence; and adjusting a base sequence in the DNA encoding result on the basis of the random sequence to obtain a randomized DNA encryption sequence. By means of a code table consisting of selected bases, encoding conversion can be performed on a file to be encoded, so as to obtain a DNA encryption sequence, thereby achieving DNA encryption of said file, and improving the encryption security and efficiency.

Classes IPC  ?

• H04L 9/40 - Protocoles réseaux de sécurité

Abrégé

The present invention relates to an engineered bacterium for producing ansamitocin as well as a construction method therefor and the use thereof. The engineered bacterium overexpresses a FtsH protein. No study has reported the relationship between FtsH and ansamitocin. The present invention finds that the cell division protein FtsH is related to the synthesis of ansamitocin, and overexpressing FtsH can increase the yield of ansamitocin, thus saving the cost of industrial production of ansamitocin and increasing the fermentation efficiency. Therefore, the present invention is of great significance for realizing the industrial development of anti-tumor drugs in China, expanding the application range, and promoting clinical diagnosis and treatment of cancers.

Classes IPC  ?

• C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora
• C12N 15/57 - Hydrolases (3) agissant sur les liaisons peptidiques (3.4)
• C12N 9/52 - Protéinases provenant de bactéries
• C12P 17/18 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle contenant plusieurs hétérocycles condensés entre eux ou condensés avec un système carbocyclique commun, p. ex. rifamycine
• C12R 1/01 - Bactéries ou actinomycètes

Abrégé

Disclosed in the present invention are a brain tissue removal tool and a use method therefor. The brain tissue removal tool comprises a guide rod and a tissue removal rod; the guide rod has a cylindrical structure; one end of the tissue removal rod is a resecting end, wherein the length of the resecting end does not exceed the length of the guide rod, and the resecting end can extend into the guide rod and is movable in the guide rod; and the other end of the tissue removal rod is an operating end, and a limiting block is provided on the tissue removal rod, wherein the limiting block is provided between the resecting end and the operating end, and is in stop fit with the top surface of the guide rod. The present invention has the advantages of a simple structure, convenient operations, and low costs, and can guarantee smooth implantation of an endoscope without pressing and damaging a target brain area, thereby preventing the field of view of a lens from being blocked, avoiding resource waste, and saving material costs, time costs and labor costs.

Classes IPC  ?

• A61D 1/00 - Instruments de chirurgie vétérinaire

Abrégé

An electrical stimulator device for primary cultured neurons, the electrical stimulator device for primary cultured neurons comprising a support (100) and platinum wire electrodes (200), wherein a lower end of the support (100) can extend into a container where neurons are planted; the support (100) is provided with two fixing members (110) arranged in parallel; and two platinum wire electrodes (200) are provided, one end of each platinum wire electrode (200) being connected to an external power supply, the other end of each platinum wire electrode (200) being fixed on a respective fixing member (110), and the parts of the two platinum wire electrodes (200) in contact with the neurons being arranged in parallel.

Classes IPC  ?

• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores

Abrégé

An animal self-administration method and apparatus, an animal self-administration device, and a storage medium. The method comprises: acquiring posture data of a target object in an active region of the animal self-administration device; performing data comparative analysis on the posture data and historical posture data to obtain posture change data, determining a rotation angle and a rotation direction of a stepping motor (24) on the basis of the posture change data, and generating an angle adjustment signal; and on the basis of the angle adjustment signal, the rotation angle, and the rotation direction, allowing the stepping motor (24) to control a converter (25) to rotate synchronously, so as to drive an administration flexible tube and a data transmission line connected to the converter (25) to rotate. By means of the posture data of the target object, the converter (25) can be controlled to rotate synchronously, thereby rotating the administration flexible tube and the data transmission line connected to the converter (25), and preventing the administration flexible tube and the data transmission line from being wound due to the movement of the target object.

Classes IPC  ?

• A61D 7/00 - Dispositifs ou méthodes pour l'introduction de remèdes, solides, liquides ou gazeux ou d'autres produits dans ou sur le corps des animaux
• A01K 1/03 - Logements pour animaux domestiques ou de laboratoire
• A01K 29/00 - Autres appareils pour l'élevage

Abrégé

Disclosed are a composite aluminum material and a preparation method therefor, a battery negative electrode material, and a battery. The composite aluminum material comprises an aluminum sheet and a twin-crystal metal material coated on the upper surface and the lower surface of the aluminum sheet. The design of the sheet structure allows for surface-to-surface contact between aluminum materials, thereby reducing contact resistance between the materials. The twin-crystal metal coating serves as an oxygen barrier to prevent rapid oxidation of the aluminum materials in air, and has good dual conduction capability for ions and electrons, thereby facilitating coupling of the electrons and the ions in the aluminum negative electrode material. Finally, the structural design effectively mitigates the electrochemical polarization problem of the small-sized aluminum negative electrode material, thereby facilitating activation of the electrochemical performance thereof. In addition, the present invention further provides a composite aluminum sheet having a twin-crystal metal coating, which is prepared in a bottom-up manner; and an aluminum metal film is deposited on a carbon-coated polymer film substrate by means of a physical vapor deposition method, such that the problem of continuous oxidation of an aluminum sheet in a bottom-up preparation process is solved.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs

Abrégé

Embodiments of the present application belong to the technical field of image enhancement, and provide a super-resolution reconstruction method and apparatus for a magnetic resonance image, a device, and a storage medium. The method comprises: incorporating a total variation norm and a learnable regularization term into an image reconstruction model, inputting Gaussian random noise and a first low-resolution magnetic resonance image into the image reconstruction model, performing high-resolution image reconstruction on the Gaussian random noise, and obtaining a first high-resolution magnetic resonance image; by means of the image reconstruction model, degrading the first high-resolution magnetic resonance image into a second low-resolution magnetic resonance image; on the basis of the first low-resolution magnetic resonance image and the second low-resolution magnetic resonance image, optimizing network parameters of the image reconstruction model, and obtaining optimized network parameters; and, on the basis of the optimized network parameters, reconstructing the Gaussian random noise into a target high-resolution magnetic resonance image, so that the generalization ability and the reconstruction effect of the image reconstruction model are improved.

Classes IPC  ?

• G06T 3/4053 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement basé sur la super-résolution, c.-à-d. où la résolution de l’image obtenue est plus élevée que la résolution du capteur

Abrégé

Embodiments of the present application relate to the technical field of image processing, and provide a high-resolution image reconstruction method and apparatus, a computer device and a storage medium. The method comprises: acquiring a low-resolution image, wherein the low-resolution image is obtained by reducing the resolution of a high-resolution target image; inputting the low-resolution image into an image reconstruction network of at least two stages; by means of the image reconstruction network, carrying out high-resolution reconstruction on the low-resolution image to obtain a preliminarily reconstructed image; on the basis of the preliminarily reconstructed image and the target image, carrying out parameter adjustment on the image reconstruction network of the next stage; by means of the adjusted image reconstruction network, carrying out high-resolution reconstruction on the low-resolution image to obtain an updated reconstructed image; and on the basis of the updated reconstructed image and the target image, carrying out parameter adjustment on the image reconstruction network of the further next stage until the image reconstruction network of the final stage outputs a high-resolution image. The embodiments of the present application can effectively improve the reconstruction effect of high-resolution images by means of prior information.

Classes IPC  ?

• G06T 3/40 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement

Abrégé

Provided are a neural electric impulse detection method and system, and a terminal. The method comprises: acquiring an original neuroelectrophysiological signal, and performing filtering and threshold detection on the original neuroelectrophysiological signal to obtain a first neural electric impulse signal sample (S100); applying a skewed distribution assumption to the first neural impulse signal, obtaining, according to the moment estimation of a skewed distribution, a first probability density parameter, a location parameter, and a scale parameter of the skewed distribution of the first neural electric impulse signal sample, and obtaining, according to the first probability density parameter, the location parameter, and the scale parameter, a first probability density function (S200); determining whether the first probability density parameter is less than zero, and if so, using the first neural electric impulse signal sample as a second neural electric impulse signal sample (S300); using kernel density estimation to perform a calculation on the second neural electric impulse signal sample to obtain a second probability density function (S400); and calculating information divergence between the first probability density function and the second probability density function, determining, according to the information divergence, whether the first neural electric impulse signal sample belongs to a neural electric impulse, and outputting a determination result (S500). The method has the advantages of rapidness, high efficiency, high noise resistance, good specificity, and eliminating the need for template matching.

Classes IPC  ?

• A61B 5/374 - Détection de la répartition de fréquence dans les signaux, p. ex. détection des ondes delta, thêta, alpha, bêta ou gamma

Abrégé

The present invention relates to the technical field of physiological signal waveform classification, and in particular to a waveform classification model training method and a physiological signal waveform classification method. In the present invention, each convolution basic block of a convolution module in a neural network model comprises a grouped convolution layer and a shuffling operation layer; a convolution kernel of the grouped convolution layer uses a dilated convolution; both the dilated convolution and a grouped convolution are computationally lightweight; in addition, the convolution basic block is also provided with the shuffling operation layer; the shuffling operation layer can perform cross combination on features output by channels in an input layer of a grouped convolution, so that a final feature map output by the grouped convolution covers feature information in all the channels in the input layer, to ensure the accuracy of the features output by the convolution basic block where the grouped convolution is located, thereby ensuring the accuracy of psychological signal waveform classification.

Classes IPC  ?

• G06F 18/24 - Techniques de classification

Abrégé

Provided are a cryogenic apparatus, a cryogenic method, and a cryosurgical instrument. The cryogenic apparatus comprises a cryoprobe (100), an evaporation member (200), and a liquid storage assembly (400). The evaporation member (200) is connected to the cryoprobe (100). The evaporation member (200) is provided with an accommodating tank for accommodating a cryogenic liquid. The cryogenic liquid in the accommodating tank volatilizes, lowering the temperature of the evaporation member (200) and the cryoprobe (100). The cryoprobe (100) is provided with a capillary tube (110), and the capillary tube (110) is in communication with the accommodating tank, so that part of the cryogenic liquid in the accommodating tank is conveyed to the cryoprobe (100) by means of the capillary tube (110). The cryogenic liquid conveyed to the cryoprobe (100) volatilizes and absorbs heat, further lowering the temperature of the cryoprobe (100), so that the cryoprobe (100) can still stably meet the expected temperature requirement when the ambient temperature is relatively high. The present invention reduces operational difficulty, saving both time and effort.

Classes IPC  ?

• A61B 18/02 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par refroidissement, p. ex. techniques cryogéniques

Abrégé

Disclosed in the present application is a fixing apparatus for repeated positioning imaging of an animal skin window. The present application relates to the technical field of medical instruments. In the case of ensuring the resolution of the imaging system, the present application not only simplifies the imaging steps, which reduces the difficulty of imaging, but also improves the quality of the resulting images. The apparatus comprises a skin window apparatus and a fixing apparatus, wherein the skin window apparatus comprises a support piece, a fixing ring, and an optical plastic sheet; the support piece comprises a connecting part and a bent part; an imaging hole is formed in the center of the connecting part; the fixing ring is arranged in the imaging hole; the optical plastic sheet is arranged in the fixing ring; a plurality of elongated holes arranged linearly are formed in the connection between the bent part and the connecting part; the support piece is made of a stainless steel material; the fixing apparatus comprises a fixing base, a limiting fixing assembly, a porous fixing plate, a pitching adjuster, a three-axis displacement stage, and a magnetic attraction base which are sequentially arranged from top to bottom; the connecting part of the support piece is connected to the upper surface of the fixing base, and the bent part of the support piece is suspended.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61D 3/00 - Appareils pour soutenir ou ligoter les animaux à opérer

Abrégé

Disclosed is an encoding and decoding method for DNA storage of video data. The method comprises: splitting a target video to obtain a plurality of video segments of the target video; analyzing each video segment to obtain video information of the video segment, and converting the video information of each video segment into a corresponding sequence to be encoded, wherein the sequence to be encoded is an N-ary sequence, and the video information comprises multimedia information and meta-information; on the basis of a bit-base mapping rule, encoding the sequences to be encoded into a plurality of base sequences respectively corresponding to the video segments; and adding corresponding preset primers to the plurality of base sequences, and performing DNA synthesis on the base sequences having the added primers and storing same, so as to obtain DNA storage data of the target video, wherein the preset primers are related to the positions in the target video of the video segments corresponding to the base sequences. By segmenting a target video that needs to be stored and implementing parallel encoding, the present invention achieves rapid encoding of the target video.

Classes IPC  ?

• H04N 19/423 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques caractérisés par les détails de mise en œuvre ou le matériel spécialement adapté à la compression ou à la décompression vidéo, p. ex. la mise en œuvre de logiciels spécialisés caractérisés par les dispositions des mémoires
• G06N 3/12 - Agencements informatiques fondés sur des modèles biologiques utilisant des modèles génétiques

Abrégé

Disclosed in the present invention are an ontology-based product carbon footprint assessment method and a related device. The method comprises: on the basis of a published input-output table, calculating full lifecycle carbon emissions generated by means of the industry's average output value; then, by means of Taylor series expansion, calculating carbon emissions at different stages of the full industrial chain of a product, and identifying the stages with the highest carbon emissions; and finally performing accurate data replacement for the stages with high carbon emissions. The present invention provides a foundational database capable of being associated with an industrial activity relationship, provides a standardized ontology-based product carbon footprint assessment model based on the industry average, and embeds an inference algorithm to achieve automatic completion of an enterprise carbon footprint model, such that the standardization of carbon emission calculation and the transparency of carbon emissions at each production stage of a product are achieved, thereby helping enterprises to quickly assess their own product carbon footprints and benchmark against the industry carbon footprint.

Classes IPC  ?

• G06Q 10/0639 - Analyse des performances des employésAnalyse des performances des opérations d’une entreprise ou d’une organisation

Abrégé

An energy spectrum image processing method and apparatus, a device, and a storage medium. The method comprises: determining an initial substance base image (S110); determining a current iteration result corresponding to a current number of diffusion steps to obtain current noise data corresponding to the current iteration result, and on the basis of the current noise data, performing noise reduction processing on the current iteration result to update the current iteration result (S120); and taking an updated current iteration result as a target substance base image (S130).

Classes IPC  ?

• G06T 11/00 - Génération d'images bidimensionnelles [2D]

Abrégé

Disclosed in the present invention are a dual-gear-pump in-vitro blood flow simulation device, method and system based on closed-loop feedback. The device comprises a liquid source, a flow generator, a flow sensor, a simulated blood vessel and a controller, wherein an outlet of the liquid source is in communication with an inlet of the flow generator, an outlet of the flow generator is in communication with an inlet of the simulated blood vessel via the flow sensor, and an outlet of the simulated blood vessel is in communication with an inlet of the liquid source; and an input end of the controller is connected to an output end of the flow sensor, an output end of the controller is connected to a control end of the flow generator, and the controller performs step-by-step control on the flow generator in a closed-loop feedback control manner on the basis of the flow measured by the flow sensor. The device, method and system can match the output flow of a pump with a target flow waveform, and also have the characteristics of shorter time consumption and simple operation.

Classes IPC  ?

• G09B 23/30 - Modèles anatomiques

Abrégé

Disclosed are a multi-channel balloon electrode, a method for preparing same, and use thereof. The method comprises the following steps: preparing a balloon with a thermoplastic polyurethane rubber, and using a hot melt adhesive to seal the two ends of the balloon; conformally attaching a patterned mask to the outer surface of the balloon; depositing a multi-channel conductive electrode on the balloon by means of vacuum magnetron sputtering deposition or vapor deposition; and packaging the multi-channel conductive electrode. The balloon electrode prepared in the present invention solves the problems in the prior art such as complicated electrode preparation procedures, limited electrode functionality, poor electrode precision and electrode stability, low scalability and the like, and is suitable for mass production. The balloon electrode can be used for mapping and electrical stimulation, and has potential application prospects in the medical field.

Classes IPC  ?

• A61B 18/14 - Sondes ou électrodes à cet effet

Abrégé

The present application relates to the technical field of computers, and in particular to a verifiable ledger database storage extension method and system, capable of solving, to a certain extent, the problems of how to improve authenticated data structures to improve query efficiency, and balancing storage and calculation overheads caused by security requirements. The method comprises: introducing a sharding extension protocol, wherein the sharding extension protocol abstracts a database layer interface to provide transparent service for a lower-layer application; introducing a synchronization control protocol, wherein the synchronization control protocol improves a storage engine interface to implement two-tier storage with read-write separation, and defines a cross-shard transaction snapshot format on the basis of a Merkle tree and a derivative verifiable index structure; and designing a storage engine to optimize the locality of index data.

Classes IPC  ?

• G06F 16/21 - Conception, administration ou maintenance des bases de données

Abrégé

Provided is use of an endoperoxide in preparing an anti-microbial drug. In an anoxic condition, the endoperoxide can partially and effectively inhibit the survival of Mycobacterium tuberculosis. Provided is use of an endoperoxide in combination with a respiratory chain inhibitor in preparing an anti-microbial drug. The endoperoxide includes artemisinin and derivatives thereof, and other endoperoxides with a two-oxygen bridge structure. The endoperoxide has synergistic effects with a variety of respiratory chain inhibitors, and the combination has a more effective inhibition effect on Mycobacterium tuberculosis.

Classes IPC  ?

• A61K 31/366 - Lactones ayant des cycles à six chaînons, p. ex. delta-lactones
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61P 31/06 - Agents antibactériens pour le traitement de la tuberculose

Abrégé

The present disclosure relates to the field of electrophysiological detection and monitoring technology, and in particular, to a minimally invasive implant fiber electrode of a sheath-core structure and a method for preparing same. The method comprises: 1, preparation of printing pastes: separately preparing a conductive paste and an encapsulation paste; 2, loading of pastes: loading the prepared conductive paste into an inner channel, and loading the encapsulation paste into an outer channel; 3, determination of printing track and implant printing: determining a track of printing with the assistance of a magnetic resonance image, drilling using a surgical instrument or directly inserting a coaxial injection needle at a target position, and printing the electrode; and 4, interface design: inserting, after the printing is finished, a lead wire into an end of the uncured coaxial fiber electrode, and allowing the conductive paste and the encapsulation paste to cure in a natural state. The present disclosure significantly reduces the manufacture complexity and cost, greatly reduces surgical traumas, and improves the biocompatibility and long-term stability of the electrode.

Classes IPC  ?

• A61B 5/263 - Électrodes bioélectriques à cet effet caractérisées par les matériaux des électrodes

Abrégé

A quantitative parametric brain imaging method and apparatus, and a device and a medium. The method comprises: on the basis of a short-axis-view positron emission computed tomography (PET) imaging result of a brain, acquiring a reference drug-metabolism time-activity curve of a preset reference brain part (S110); on the basis of a mapping relationship between the reference drug-metabolism time-activity curve and a drug-metabolism time-activity curve of the descending aorta, determining a target drug-metabolism time-activity curve of the descending aorta (S120); and on the basis of the target drug-metabolism time-activity curve and a preset pharmacokinetic model, completing a target cerebral pharmacokinetic parametric image (S130).

Classes IPC  ?

• G06T 11/00 - Génération d'images bidimensionnelles [2D]
• G16H 30/00 - TIC spécialement adaptées au maniement ou au traitement d’images médicales
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G16H 70/40 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des médicaments, p. ex. leurs effets secondaires ou leur usage prévu
• A61B 6/50 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des parties du corps spécifiquesAppareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations spécialement adaptés à des applications cliniques spécifiques
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• A61B 6/03 - Tomographie informatisée

Abrégé

Disclosed are a method and system for controlling a robotic arm pressing force based on a pulse wave signal. The method comprises: acquiring a pulse wave signal of a target; acquiring an interaction force between an end of a robotic arm and the target, and determining an expected pressing force according to a mapping relation between a pressing effect and the pulse wave signal; establishing an admittance control model to convert the expected pressing force into an expected trajectory of the robotic arm; and determining, on the basis of an error between an actual trajectory and the expected trajectory of the robotic arm, a control quantity of the subsequent movement of the robotic arm by using a PID controller, so as to achieve the tracking of the expected trajectory. The present invention achieves a low-impedance and compliant interaction effect when the target of pressing is moving.

Classes IPC  ?

• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
• B25J 9/16 - Commandes à programme

Abrégé

A magnetic resonance multi-core radio frequency coil device includes a first birdcage coil and a second birdcage coil coaxially nested. The first birdcage coil includes four first end rings arranged along an axial direction and multiple first leg structures. Each first leg structure is connected to the four first end rings. The second birdcage coil includes two second end rings arranged along the axial direction and multiple second leg structures. Each second leg structure is connected to the two second end rings. The first birdcage coil is configured to transmit and receive radio frequency energy at frequencies corresponding to three different nuclides. The second birdcage coil is configured to transmit and receive radio frequency energy at a frequency corresponding to a nuclide. The nuclides corresponding to the first birdcage coil are different from the nuclide corresponding to the second birdcage coil.

Classes IPC  ?

• G01R 33/34 - Détails de structure, p. ex. résonateurs
• G01R 33/36 - Détails électriques, p. ex. adaptations ou couplage de la bobine au récepteur

Abrégé

The present application relates to the technical field of picture segmentation. Disclosed are a lightweight segmentation method and device, and a storage medium. In the method, a brand-new lightweight segmentation model is created, a structure including an encoder module and a decoder module is used in the model, and a global feature and a high-level semantic feature are transmitted by means of skip connection, that is, a self-attention feature vector having the global feature and a deep convolution feature vector having the high-level semantic feature are only transmitted to the decoder module, and a process feature vector having a local feature and a low-level semantic feature is not transmitted to the decoder module, so that the number of channels of a shallow feature vector is reduced, thereby reducing the parameter quantity and the calculation quantity, and thus making the lightweight segmentation model in the present application perform picture segmentation on a common computer terminal to obtain a target surgical site image.

Classes IPC  ?

• G06V 20/70 - Étiquetage du contenu de scène, p. ex. en tirant des représentations syntaxiques ou sémantiques

Abrégé

Disclosed in the present invention are an autophagy regulator, a preparation method therefor, and a use thereof. A dual-targeting fluorescent organic small-molecule autophagy activator and autophagy inhibitor and the use thereof aim to solve the problems of single targeting, no cell selectivity, and poor cancer cell killing effects in autophagy regulation within the prior art.

Classes IPC  ?

• C07D 401/06 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
• A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
• A61P 35/00 - Agents anticancéreux
• G01N 21/64 - FluorescencePhosphorescence

Abrégé

The present invention relates to a microfluidic multiplexed immunoassay system based on flow magnet-activated cell sorting, and a method thereof. The system comprises a multiplexed immunoassay magnetic bead preparation module, a flow magnet-activated cell sorting microfluidic chip system, an optical detection module, and an image processing module, and achieves ultra-sensitive and rapid multiplexed protein quantitative detection by means of magnetic bead coding based on different magnetic contents and microfluidic chip decoding based on flow magnet-activated cell sorting. The microfluidic multiplexed immunoassay system of the present invention has the advantages of high detection sensitivity, short detection time, high signal-to-noise ratio, convenient and simple operation and low cost, is particularly suitable for multiplexed ultra-sensitive detection for monomolecular proteins, and has a potential economic value.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
• G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present application relates to the field of social behavior classification, and provides a method and apparatus for mapping and classifying free social behaviors of multiple animals, an electronic device, and a storage medium. The method comprises: on the basis of a video of free social behaviors of multiple animals, obtaining corresponding body posture data; on the basis of the body posture data, obtaining a corresponding sequence set; obtaining a two-dimensional time sequence corresponding to each sequence, and a corresponding target time segmentation point; invoking a manifold feature model; obtaining a corresponding two-dimensional manifold representation; determining a low-dimensional behavior space on the basis of the target time segmentation point and the two-dimensional manifold representation; obtaining a low-dimensional behavior space point density; determining a target number-of-clusters model on the basis of the stability of the low-dimensional behavior space point density; obtaining an original video of social behaviors of the multiple animals; and inputting the original video of the social behaviors into the target number-of-clusters model to obtain a corresponding target behavior category. The present application solves the problems in the related art of inconsistent identification, incomplete definition and low classification efficiency of manual behavior classification.

Classes IPC  ?

• G06V 40/10 - Corps d’êtres humains ou d’animaux, p. ex. occupants de véhicules automobiles ou piétonsParties du corps, p. ex. mains

Abrégé

The present application relates to the technical field of smart mechanical apparatuses. Disclosed are a gripping device and operation machinery. The gripping device of the present application comprises a support assembly, at least two bistable elements and a driving assembly. Further, each bistable element is provided with a fixed end and a gripping end; and all the fixed ends are supported on the support assembly, and the gripping ends are cooperatively arranged. Further, the driving assembly is connected to all the gripping ends and used for driving the gripping ends to move away from each other. The gripping device and the operation machinery of the present application have operational compliance, high energy efficiency and simplified drive strategies.

Classes IPC  ?

• B25J 15/10 - Têtes de préhension avec des éléments en forme de doigts avec au moins trois éléments en forme de doigts

Abrégé

A lumen stent and a manufacturing method therefor. The lumen stent comprises a spiral tube (10) and a colloid layer (20). The colloid layer (20) is arranged around a central axis A of the spiral tube (10). The spiral tube (10) is fixedly connected to the colloid layer (20). The spiral tube (10) is configured to increase a bending radius under the action of an external force, and the colloid layer (20) is configured to expand when the spiral tube (10) increases the bending radius. The spiral tube (10) is configured to be filled with a substance to be cured (30), and the substance to be cured (30) is configured to be cured under a preset condition.

Classes IPC  ?

• A61F 2/04 - Éléments ou organes creux ou tubulaires, p. ex. vessies, trachées, bronches ou voies biliaires

Abrégé

A method and system for evaluating the survival state of a wounded person on the basis of incomplete parameters. The method comprises: acquiring visual information, audio information and thermal imaging multi-modal data of a target; inputting the multi-modal data into a feature extraction network, so as to obtain multi-modal feature data; and combining the multi-modal feature data with physiological indexes, so as to form a multi-modal data set, and on the basis of a trained survival index model, obtaining an evaluation result for the survival state of the target. The present invention provides a more comprehensive and more accurate evaluation result for the survival state of a wounded person, so as to implement rapid and accurate triage of wounded persons at a disaster site.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G06F 18/20 - Analyse
• G06F 18/213 - Extraction de caractéristiques, p. ex. en transformant l'espace des caractéristiquesSynthétisationsMappages, p. ex. procédés de sous-espace
• G06F 18/241 - Techniques de classification relatives au modèle de classification, p. ex. approches paramétriques ou non paramétriques
• G06Q 50/26 - Services gouvernementaux ou services publics

Abrégé

The present invention relates to a multi-view animal identity recognition method and device. The multi-view animal identity recognition method comprises: acquiring single-animal behavior videos at the same moment in at least two views and multi-animal behavior videos at the same moment in at least two views. A deep learning model reuse strategy is used to successively and respectively train a deep learning instance segmentation model and a deep learning identity recognition model, an animal instance segmentation task and an animal identity recognition task are designed as complementary tasks, in light of video acquisition in multiple views, the problems of needing to manually label identity data, having difficulty in labeling an animal identity set and recognizing an animal identity, and having significant errors are directly solved, and the defects of having difficulty in obtaining a robust identity feature acquisition quantity and low identity recognition accuracy are further solved. Compared with the prior art, the multi-view animal identity recognition method and device disclosed in the present application can achieve the objectives of easily obtaining the robust identity feature acquisition quantity and improving the identity recognition accuracy.

Classes IPC  ?

• G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes

Abrégé

The present invention relates to the field of targeted therapy technology, and particularly, to a carrier, a targeted nanoparticle, a method for preparing same, and use thereof. The carrier disclosed in the present invention comprises tocilizumab grafted with a terminal carboxyl group-containing dye. The targeted nanoparticle comprises a carrier and a CO-release molecule. The carrier encapsulates the CO-release molecule to form a core-shell structure. In the targeted nanoparticle based on tocilizumab, the carrier is constructed by grafting the terminal carboxyl group-containing dye, and the carrier encapsulates the CO-release molecule. The carrier possesses a targeting effect, and the photothermal effect of the carrier can achieve the regulated CO release by NIR laser or targeted and controllable CO release under free radical stimulation, thereby achieving exogenous/endogenous dual-response release of CO. The present invention features good application prospects.

Classes IPC  ?

• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
• A61K 33/26 - FerSes composés
• A61K 33/32 - ManganèseSes composés
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 9/51 - Nanocapsules
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 19/00 - Médicaments pour le traitement des troubles du squelette

Abrégé

Disclosed in the present invention are a multi-channel balloon electrode, a preparation method therefor, and use thereof. The preparation method comprises the following steps: taking a thermoplastic polyurethane elastomer thin film as a substrate material, and preparing a patterned metal layer on a surface of the thermoplastic polyurethane elastomer thin film; packaging a part of an electrode except an effective functional area to obtain a thin film electrode; and curling the thin film electrode and then packaging to obtain the balloon electrode. According to the multi-channel balloon electrode provided by the present invention, the TPU thin film is used as the substrate to first prepare the two-dimensional patterned thin film electrode which is then curled to prepare the three-dimensional balloon electrode, thereby achieving surface patterning on the three-dimensional balloon electrode. The balloon electrode provided by the present invention has the advantages of adjustable channel number and density of the electrode, controllable preparation process, diverse functionalities, and scalable production, so that the precision and anti-interference capability of the electrode can be comprehensively improved by improving the electrode density and improving the electrode material and the electrode stretchability.

Classes IPC  ?

• A61B 18/14 - Sondes ou électrodes à cet effet
• A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci

Abrégé

The present application relates to the technical field of electrode wire winding, and discloses an electrode wire winding method, an automatic electrode wire winding machine, and a storage medium. The method comprises: in response to an electrode wire winding operation for the automatic electrode wire winding machine, controlling a first tractor and a second tractor to suction and pull electrode wires on an electrode wire fixing device to obtain a target electrode wire of a preset length, and generating a heating signal; heating the target electrode wire on the basis of the heating signal and a heating device to obtain a heated target electrode wire, and generating a rotational winding signal; and performing rotational winding on the heated target electrode wire on the basis of the rotational winding signal and a rotational winding device to obtain a rotationally wound target electrode wire. According to the present invention, the electrode wire can be rapidly wound by means of the first tractor, the second tractor, the heating device, and the rotational winding device to obtain the rotationally wound target electrode wire.

Classes IPC  ?

• H01B 13/02 - Toronnage

Abrégé

The present invention provides an early screening system for Parkinson's disease, comprising: a movement module, configured to excite an eye movement of a subject; a near-infrared light source, configured to illuminate during eye movement testing; a camera module, configured to record an eye movement condition; and a processor module, configured to process and compare a movement difference between the eye movement condition and the movement module. The screening system for Parkinson's disease of the present invention uses an eye movement technique, records the eye movement excited by the movement module, compares the eye movement condition with the movement scenario to determine whether the movement difference meets a feature of Parkinson's disease, and can be used for screening and diagnosing said disease. A method has advantages of high specificity and high accuracy, and shows a specific index in an early stage of a disease.

Classes IPC  ?

• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil

Abrégé

Disclosed in the present invention is an image enhancement method based on photoacoustic microscopy imaging. The method comprises: executing multiple photoacoustic microscopy scannings on a target object to obtain three-dimensional data of the target, and obtaining scanning results of the target on a time axis by means of continuous scanning imaging; before performing a projection operation on a single imaging result, for the three-dimensional data, within a set search range, combining signals of adjacent areas in space dimension; and for the scanning results on the time axis, within a set search range, combining signals of adjacent areas in time dimension, so as to obtain an enhanced image. The present invention effectively improves the image signal-to-noise ratio of a photoacoustic microscopy system, and improves the calculation efficiency.

Classes IPC  ?

• G06T 5/70 - DébruitageLissage

Abrégé

A Lamb wave acoustic device, a sensor, and a particle manipulation apparatus and method. The Lamb wave acoustic device comprises an ultrasonic excitation assembly (100) and an ultrasonic transduction assembly (200). The ultrasonic transduction assembly (200) comprises an excitation member (210) and a first excitation electrode group. The excitation member (210) is provided with a first excitation region (211) and a second excitation region which are opposite to each other. The first excitation electrode group comprises a first electrode (220) and a second electrode (230). At least the first electrode (220) is an array electrode. The array electrode comprises a plurality of strip-shaped electrodes arranged at intervals in a first direction. The first electrode (220) and the second electrode (230) are separately electrically connected to the ultrasonic excitation assembly (100). The ultrasonic transduction assembly (200) has a first resonant frequency and/or a second resonant frequency. When the frequency of an excitation electric signal is equal to the first resonant frequency, the excitation member (210) generates a Lamb wave field. When the frequency of the excitation electric signal is equal to the second resonant frequency, the excitation member (210) generates a periodic resonant wave field. The Lamb wave acoustic device can easily excite the Lamb wave field or the periodic resonant wave field.

Classes IPC  ?

• B06B 1/02 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique
• B06B 1/20 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant un fluide vibrant
• B06B 3/00 - Procédés ou appareils spécialement adaptés pour transmettre des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore

Abrégé

A method and apparatus for processing line-of-sight information of a target object, and a device. The method comprises: acquiring first video data collected by a first camera assembly and related to eyes of a target object (202); extracting first image data and second image data from the first video data, and on the basis of the first image data and the second image data, determining pupil analysis information of the first image data and the second image data (204); on the basis of the pupil analysis information of the first image data and the second image data, calculating the abscissa and ordinate of an eye rotation center as first parameter information (206); acquiring third image data of the first camera assembly and fourth image data of a second camera assembly when the target object is observing a calibration point (208); and determining the distance between the eye rotation center of the target object and the pupils as second parameter information, so as to determine a fixation point of the target object on the basis of the first parameter information and the second parameter information of both eyes (210).

Classes IPC  ?

• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
• G06V 40/18 - Caractéristiques de l’œil, p. ex. de l’iris
• G06V 10/94 - Architectures logicielles ou matérielles spécialement adaptées à la compréhension d’images ou de vidéos
• G06F 3/00 - Dispositions d'entrée pour le transfert de données destinées à être traitées sous une forme maniable par le calculateurDispositions de sortie pour le transfert de données de l'unité de traitement à l'unité de sortie, p. ex. dispositions d'interface

Abrégé

Disclosed in the present invention are a cumulative pressure stress effect evaluation system and method. The system comprises: an animal modeling module, configured to construct various pressure stress level models by means of applying different durations of pressure to a target model animal; a spontaneous behavior capture module, configured to capture spontaneous behaviors of the target model animal corresponding to different pressure stress levels to obtain corresponding action recognition data, and construct a first data set according to a corresponding relationship between the action recognition data and the pressure stress levels; a behavior phenotype analysis module, configured to use linear discriminant analysis to perform dimension reduction on the first data set, so as to obtain a second data set in a discrimination space; and a pressure degree evaluation module, configured to use the second data set to train a machine learning model, so as to obtain an optimized cumulative pressure stress effect evaluation model. The present invention can be used for cumulative pressure stress effect evaluation, is suitable for precise medicine, and can achieve behavior phenotype difference recognition induced by the same pressure stress source and different pressure degrees.

Classes IPC  ?

• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes

Abrégé

The present invention provides a foot shock device for a head fixed animal behavior task, comprising a support member and a foot shock device rotationally connected to the support member. The foot shock device has a rotating axis parallel to a horizontal plane, the foot shock device can rotate around the rotating axis, the support member supports an experimental animal by means of the foot shock device, and the foot shock device can rotate under the driving of the feet of the experimental animal; a head fixator for fixing the head of the experimental animal is arranged above the foot shock device. The arrangement of the head fixator and the rotatable foot shock device ensures the consistency of irrelevant variables in a head fixed experimental paradigm and a free motion experimental paradigm, and achieves the effect of mutual verification in different experimental forms.

Classes IPC  ?

• A01K 15/04 - EntravesDispositifs empêchant le passage à travers une clôture

Abrégé

The present invention relates to the technical field of information interaction. Disclosed are a virtual reality display method and device for a wide field of view. The virtual reality display method for a wide field of view specifically comprises the following steps: acquiring an included angle between a central axis of the eyes of a target object and a horizontal line; on the basis of the included angle between the central axis of the eyes of the target object and the horizontal line, adjusting an included angle between a flexible display screen that is bent into a semi-cylindrical shape and a visual center of the eyes of the target object; and acquiring motion parameters of the target object that are collected by means of an attitude sensor, and projecting picture information to the flexible display screen on the basis of the motion parameters of the target object and by means of a cylindrical central projection method, so as to realize picture display. Therefore, the computational load during the display of VR helmet pictures of a small animal is reduced, thereby improving the smoothness of the pictures.

Classes IPC  ?

• H04N 13/383 - Suivi des spectateurs pour le suivi du regard, c.-à-d. avec détection de l’axe de vision des yeux du spectateur

Abrégé

A system and method for controlling an orthosis. The system comprises: a pressure detection module (2), configured to detect pressure information of an orthosis pressure applying zone; a pressure control module (3), configured to adjust the pressure information applied by an orthosis (8) according to a received pressure adjustment instruction; a blood oxygen detection module (1), configured to detect blood oxygen information of the orthosis pressure applying zone; a temperature detection module (4), configured to detect temperature information of the orthosis pressure applying zone; a temperature control module (5), configured to adjust the temperature information applied by the orthosis (8) according to a received temperature adjustment instruction; a control platform, configured to determine whether to trigger the pressure adjustment instruction and the temperature adjustment instruction or not according to one or more of the received pressure information, blood oxygen information, and temperature information. The system can monitor the skin and muscle tissue conditions in the orthosis pressure applying zone in real time and provide early warning of abnormal conditions. Moreover, the system has a low cost and is worn comfortably and suitable for long-term wearing and daily monitoring.

Classes IPC  ?

• A61F 5/01 - Dispositifs orthopédiques, p. ex. dispositifs pour immobiliser ou pour exercer des pressions de façon durable pour le traitement des os fracturés ou déformés, tels que éclisses, plâtres orthopédiques ou attelles
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale

Abrégé

The present disclosure relates to a robotic system for respiratory diagnosis and treatment and a control method therefor. The present disclosure includes a master control apparatus for operating and controlling a control instruction, a slave control apparatus for receiving the control instruction of the master control apparatus and operating an operation action, and a navigation apparatus for guiding the slave control apparatus. The slave control apparatus includes a slave robot and a slave embedded controller installed inside the slave robot. The slave robot is provided with a mechanical arm, a propulsion support plate connected to the mechanical arm, a biopsy instrument introduction mechanism connected to a propulsion support plate for delivering a biopsy instrument, a bronchoscope rotation driving mechanism for controlling a bronchoscope, and a bending control mechanism for controlling an angle of a flexible end of the bronchoscope.

Classes IPC  ?

• A61B 34/37 - Robots meneurs-suiveurs
• A61B 1/005 - Endoscopes flexibles
• A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p. ex. laryngoscopes, bronchoscopes
• A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
• A61B 34/30 - Robots chirurgicaux

Abrégé

The present application relates to the technical field of computers, and provides a training data set generation method and apparatus, an electronic device, and a storage medium. The method comprises: acquiring a raw video; on the basis of the raw video, determining movement trajectories and movement backgrounds of objects in a set scene, and on the basis of a first number of video frames in the raw video, determining the contours of the objects in the first number of video frames; on the basis of the contours of the objects in the first number of video frames, performing self-training on a second number of video frames in the raw video to obtain the contours of the objects in all the video frames; and on the basis of the movement trajectories of the objects in the set scene, fusing the contours and the movement backgrounds of the objects in the corresponding video frames to form a training data set, wherein training data in the training data set is video frames in which objects having different occlusion relationships all have undergone instance labeling. The present application solves the problem in the prior art that data for multi-object pose estimation is deficient.

Classes IPC  ?

• G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”

Abrégé

Disclosed in the present invention is a local feature optimization-based visible light and infrared pedestrian re-identification method. The method comprises: collecting a target area image, the target area image comprising a visible light-mode image and an infrared-mode image; and inputting the target area image into a pedestrian identification model to obtain a pedestrian identification result, wherein the pedestrian identification model comprises a local feature extraction module, a local feature alignment module and a feature collaborative learning module, the local feature extraction module extracts local features of the visible light mode and infrared mode, the local feature alignment module groups and aligns cross-modal local features, so as to establish cross-modal connections, and the feature collaborative learning module enhances each local feature and performs collaborative optimization on the global features and the local features. The present invention can adaptively mine cross-modal local features, directly establish rich alignment relationships for the cross-modal local features, and embed context relationships of global features into the local features, thus remarkably improving the accuracy of pedestrian identification.

Classes IPC  ?

• G06V 40/10 - Corps d’êtres humains ou d’animaux, p. ex. occupants de véhicules automobiles ou piétonsParties du corps, p. ex. mains

Abrégé

The present invention relates to a wearable motion-assisting exoskeleton system for ocean diving operation, comprising a waist belt, a first power system and a second power system. One end of a front-side steel wire rope of the first power system is fixed to the front side of a knee pad, the other end of the front-side steel wire rope is wound on a track G1 of a wire winding disc, and a tail-end wire head X1 penetrates through a first wire head; one end of a rear-side steel wire rope is fixed to the rear side of the knee pad, the other end of the rear-side steel wire rope is wound on a track G2 of the wire winding disc, and a tail-end wire head X2 penetrates through a second wire head; and the first wire head is fixedly mounted at a recess E1 of the track G1, and the second wire head is fixedly mounted at a recess E2 of the track G2. The second power system and the first power system are consistent in structure, and are symmetrically distributed on two sides of the waist belt. According to the present invention, the connection mode is switched by means of the structure of specially-made wire heads, thereby achieving stable power transmission of the exoskeleton when motion assistance is needed, and the motion of lower limbs in a non-assistance state is not limited by the mechanical limitation of lasso transmission.

Classes IPC  ?

• B63C 11/02 - Équipement de plongeurs

Abrégé

The present disclosure discloses a method and apparatus for enhancing a PET parameter image, a device, and a storage medium. The method includes: obtaining, based on a preset mapping list, an input image corresponding to an original PET parameter image determined based on a dynamic PET image set; and inputting the input image into an image enhancement model, adjusting a model parameter of the image enhancement model based on the original PET parameter image and an output predicted PET parameter image until a preset number of iterations is met, and using the predicted PET parameter image as a target PET parameter image corresponding to the original PET parameter image; wherein the input image is a noise image, a dynamic PET image corresponding to a preset acquisition time range in the dynamic PET image set or a dynamic SUV image corresponding to the dynamic PET image.

Classes IPC  ?

• G06T 5/60 - Amélioration ou restauration d'image utilisant l’apprentissage automatique, p. ex. les réseaux neuronaux
• G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
• G06T 5/70 - DébruitageLissage

Abrégé

The present disclosure discloses a chemical shift coded imaging method based on a transition region and regional iterative phasor extraction. Acquiring an initial image, and determining an initial phasor solution of the transition region based on the initial image; performing regional iterative phasor extraction in at least two set directions by taking the initial phasor solution as initial information, and obtaining a target phasor solution based on a regional iterative phasor extraction result corresponding to each set direction; and determining a first chemical composition signal and a second chemical composition signal based on the target phasor solution, and performing chemical shift coded imaging based on the first chemical composition signal and/or the second chemical composition signal. By means of regional iterative phasor extraction in a plurality of dimensions, wrong phasor information is transferred independently along different dimensions, wrong information transferred in different directions is excluded.

Classes IPC  ?

• G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
• G06V 10/26 - Segmentation de formes dans le champ d’imageDécoupage ou fusion d’éléments d’image visant à établir la région de motif, p. ex. techniques de regroupementDétection d’occlusion
• G06V 10/36 - Utilisation d’un opérateur local, c.-à-d. des moyens pour opérer sur des points d’image situés dans la proximité d’un point donnéOpérations de filtrage locales non linéaires, p. ex. filtrage médian

Abrégé

Provided are a method for detecting a homogeneous protein, and a detection platform. The method comprises: constructing a target protein recognition element by using a small-molecule-modified primer; the protein recognition element recognizing a target protein; recognizing, by using a CRISPR/Cas12a system, a product from target protein recognition, and generating a detectable fluorescence signal. In the provided detection method and platform, the inhibitory effect resulting from specific binding to the target protein is introduced into the RCA amplification process, thereby affecting the signal output of CRISPR/Cas12a; and the method achieves a detection sensitivity below the picomolar level for both SA and Anti-dig, with a detection efficiency approximately 1000 times that of previously reported methods. The platform has great potential in the aspect of detecting real samples (such as human serum), and also shows excellent specificity during competitive experiments on free small molecules. In addition, by changing the recognition element, the present invention can be suitable for homogeneous analysis of different protein types, thereby achieving universality and providing a new direction for quantifying a protein biomarker at an ultra-low concentration in clinical practice.

Classes IPC  ?

• C12Q 1/6804 - Analyse d’acides nucléiques utilisant des immunogènes
• C12Q 1/6816 - Tests d’hybridation caractérisés par les moyens de détection
• C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

A composite nanowire and a preparation method therefor, a thin film, and a conductive element, relating to the technical field of battery materials. The preparation method for the composite nanowire comprises: providing a mixed solution, wherein the mixed solution comprises nanofibers and a metal precursor; providing a base film, and applying the mixed solution on the base film; and using an inert gas lamp to irradiate the mixed solution on the base film to obtain a composite nanowire. The preparation method for the composite nanowire involves a simple process and has low costs, and the prepared composite nanowire has high purity and controllable diameter.

Classes IPC  ?

• H01B 5/14 - Conducteurs ou corps conducteurs non isolés caractérisés par la forme comprenant des couches ou pellicules conductrices sur supports isolants
• H01B 1/02 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement de métaux ou d'alliages
• H01B 13/00 - Appareils ou procédés spécialement adaptés à la fabrication de conducteurs ou câbles

Abrégé

500500 of 3.0, and the gas vesicles are synthesized by microorganisms. According to the present application, it has been discovered that modification with different amounts of PEG can result in different metabolic durations of GVs in animals, and it has also been discovered that gas vesicles with good performance can be obtained without using excessive amounts of PEG for modification.

Classes IPC  ?

• A61K 49/22 - Préparations pour échographiePréparations pour imagerie par ultrasons

Abrégé

A cellular mechanical property measurement and sorting method comprises: cells to be sorted being arranged in a straight line after passing through a standing wave acoustic field generated by a first interdigital transducer; the cells flowing through a focused acoustic field generated by a second interdigital transducer, and the focused acoustic field generating a radiation force on the cells, such that the cells are deformed; performing calculation according to information of the radiation force and deformation, so as to obtain elastic moduli of the cells; determining the positions of the cells, and selectively driving, with designed delay time, interdigital transducers in a cell sorting unit according to the moving speeds of the cells and the distances between the cells and the sorting unit, and triggering, according to the elastic moduli, a corresponding interdigital transducer to generate a planar acoustic field, so as to sort the cells.

Classes IPC  ?

• G01N 15/149 - Techniques de recherche optique, p. ex. cytométrie en flux spécialement adaptées au tri des particules, p. ex. selon leur taille ou leurs propriétés
• G01N 15/10 - Recherche de particules individuelles
• G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
• G01N 15/1404 - Manipulation du flux, p. ex. focalisation hydrodynamique

Abrégé

The present description relates to the technical field of PET image processing, and provides a model training method and apparatus, and a CT-free PET image attenuation correction method and apparatus. The training method comprises: creating a cycle generative adversarial network comprising a first generative adversarial network and a second generative adversarial network; training the cycle generative adversarial network, so that the first generative adversarial network learns a mapping relationship that a PET image that is not subjected to attenuation correction is converted into a PET image subjected to attenuation correction, and the second generative adversarial network learns a mapping relationship that the PET image subjected to attenuation correction is converted into the PET image that is not subjected to attenuation correction; and when the cycle generative adversarial network obtained by current training satisfies a preset condition, determining a first generator in the first generative adversarial network to be a CT-free PET image attenuation correction model. The embodiments of the present description can reduce the harmful radiation dosage while ensuring the quality of PET image attenuation correction.

Classes IPC  ?

• G06T 11/00 - Génération d'images bidimensionnelles [2D]
• G06N 3/0475 - Réseaux génératifs
• G06N 3/094 - Apprentissage antagoniste

Abrégé

Disclosed in the present invention is a pressure calculation method based on integration of a spherical/arc surface structure and a flexible pressure array. The method comprises: collecting pressure array information of interaction between a pressing end and a target, wherein the pressure array information reflects sensed pressures that are in different directions of a three-dimensional space and generated when the pressing end comes into contact with the target; inputting the pressure array information into a trained neural network model, so as to obtain a normal force and a tangential force of a corresponding contact surface; and controlling a subsequent operation of the pressing end on the basis of the normal force and the tangential force. The present invention can establish an intrinsic relationship between a three-dimensional force and a pressure sensing array, thereby realizing accurate calculation of a three-dimensional pressing force that is based on flexible pressure array information.

Classes IPC  ?

• G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle