TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Suss, Matthew E.
Sahray, Zohar
Shocron, Amit N.
Uwayid, Rana
Mathur, Ankita
Diesendruck, Charles E.
Nijem, Sally
Abrégé
The present invention relates to resin-free ion-exchange using an electrode capacitor assembly comprising an anode and a cathode which are both functionalized with negatively charged groups.
C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse
C02F 103/08 - Eau de mer, p. ex. pour le dessalement
H01G 11/30 - Électrodes caractérisées par leur matériau
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Dotan, Hen
Grader, Gideon
Abrégé
The technology subject of the present application concerns an electrolyzer comprising a plurality of electrolysis cells and a method of generating hydrogen and oxygen gases.
Technion Research and Development Foundation Limited (Israël)
Inventeur(s)
Haick, Hossam
Tang, Ning
Abrégé
The present invention provides a self-healing biocompatible elastomer comprising polymeric chains comprising units of formula (A1), wherein R1 is selected from the group consisting of a linear (C2-C20) alkylene and —R4-S—S—R4′-, wherein R4 and R4′ are independently a linear (C1-C10) alkylene; R2 is a linear or cyclic (C4-C10) alkylene; and R3 is selected from the group consisting of a polybutadiene, a polybutene, a polyethylene, a polypropylene, and a polyisoprene, wherein the elastomer is crosslinked by hydrogen bonds between urethane linkages. Further provided is a one-pot method for preparing a self-healing biocompatible elastomer. The invention further provides an antibacterial composition and a wound dressing comprising the self-healing biocompatible elastomer. Formula (A1)
The present invention provides a self-healing biocompatible elastomer comprising polymeric chains comprising units of formula (A1), wherein R1 is selected from the group consisting of a linear (C2-C20) alkylene and —R4-S—S—R4′-, wherein R4 and R4′ are independently a linear (C1-C10) alkylene; R2 is a linear or cyclic (C4-C10) alkylene; and R3 is selected from the group consisting of a polybutadiene, a polybutene, a polyethylene, a polypropylene, and a polyisoprene, wherein the elastomer is crosslinked by hydrogen bonds between urethane linkages. Further provided is a one-pot method for preparing a self-healing biocompatible elastomer. The invention further provides an antibacterial composition and a wound dressing comprising the self-healing biocompatible elastomer. Formula (A1)
C08G 18/75 - Polyisocyanates ou polyisothiocyanates cycliques cycloaliphatiques
A61L 15/26 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carboneLeurs dérivés
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
C08G 18/38 - Composés de bas poids moléculaire contenant des hétéro-atomes autres que l'oxygène
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Suss, Matthew E.
Asokan, Arunchander
Abu Khalla, Shada
Abrégé
The present invention provides a non-biological deionization fuel cell (DFC) comprising, inter alia, a cathode comprising a non-platinum group metal and a nitrogen doped carbon matrix. Further provided is a method of preparing the catalyst through a zeolitic imidazolate framework precursor.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Zohar, Barak
Debbi, Lior
Abrégé
The present invention provides stem cells-derived extracellular vesicles (EVs) characterized by upregulation and/or downregulation of specific proteins. Composition comprising the EVs. and their use in the treatment of diseases and disorders associated with the upregulated proteins are also provided.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Shilo, Shimon
Ezri, Doron
Ginzberg, Nimrod
Cohen, Emanuel
Abrégé
A full-duplex carrier aggregation RF wireless transceiver (100) is disclosed. The RF wireless transceiver (100) comprises a single transmit and receive antenna (110) configured to perform a RF transmission based on a transmit signal and to generate a receive signal based on a RF reception and a plurality of cascaded quadrature balanced power amplifier, QBPA, modules (120a-n), wherein each QBPA module (120a-n) comprises a transmit signal port (121a, b), an antenna port (122a, b), a receive signal port (123a, b), and a cancellation signal port (124a, b), wherein the antenna port (121a) of a first QBPA module (120a) is connected to the antenna (110) and wherein the antenna port (121b) of a second QBPA module (120b) is connected to the receive signal port of the first QBPA module (120a). Each QBPA module (120a-n) is configured to: receive a transmit input signal at the transmit signal port (121a, b); receive a receive signal at the antenna port (122a, b); receive a cancellation input signal at the cancellation signal port (124a, b); generate a transmit signal based on the transmit input signal and output the transmit signal via the antenna port (122a, b); generate a cancellation signal based on the cancellation input signal and output the cancellation signal and the receive signal at the receive signal port (123a, b).
H04B 1/525 - Dispositions hybrides, c.-à-d. dispositions pour la transition d’une transmission bilatérale sur une voie à une transmission unidirectionnelle sur chacune des deux voies ou vice versa avec des moyens de réduction de la fuite du signal de l’émetteur vers le récepteur
H04B 1/00 - Détails des systèmes de transmission, non couverts par l'un des groupes Détails des systèmes de transmission non caractérisés par le milieu utilisé pour la transmission
H03F 1/32 - Modifications des amplificateurs pour réduire la distorsion non linéaire
H03F 1/56 - Modifications des impédances d'entrée ou de sortie, non prévues ailleurs
H03F 3/60 - Amplificateurs dans lesquels les réseaux de couplage ont des constantes réparties, p. ex. comportant des résonateurs de guides d'ondes
8.
RF WIRELESS TRANSCEIVER FOR FULL DUPLEX COMMUNICATION WITH LEAKAGE CANCELLATION
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Ezri, Doron
Shilo, Shimon
Keren, Rani
Ginzberg, Nimrod
Cohen, Emanuel
Abrégé
A RF wireless transceiver (100) for full-duplex communication is disclosed. The RF wireless transceiver (100) comprises a single transmit and receive antenna (110) configured to perform a RF transmission based on a transmit signal and to generate a receive signal based on a RF reception. Moreover, the RF wireless transceiver (100) comprises a quadrature balanced power amplifier, QBPA, module (120), wherein the QBPA module (120) comprises a transmit signal port (121), an antenna port (122) connected to the antenna (110), a receive signal port (123), and a cancellation signal port (124), and wherein the QBPA module (120) is configured to: receive a transmit input signal at the transmit signal port (121); receive a receive signal at the antenna port (122); generate a transmit signal based on the transmit input signal and output the transmit signal via the antenna port (122); and reflect a portion of the transmit signal to the cancellation signal port (124). The RF wireless transceiver (100) further comprises a cancellation input signal generator (130) configured to generate, based on the reflected portion of the transmit signal, a cancellation input signal at the cancellation signal port (124) of the QPBA module (120). The QBPA module (120) is further configured to generate a cancellation signal based on the cancellation input signal and output the receive signal and the cancellation signal at the receive signal port (123) for nulling transmission leakage.
H04B 1/525 - Dispositions hybrides, c.-à-d. dispositions pour la transition d’une transmission bilatérale sur une voie à une transmission unidirectionnelle sur chacune des deux voies ou vice versa avec des moyens de réduction de la fuite du signal de l’émetteur vers le récepteur
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Bar-On, Yotam
Khateeb, Dina
Abrégé
The present invention provides inhibitory molecules for inhibiting or at least partially preventing the binding of influenza virus hemagglutinin (HA) with Lymphocyte activation gene 3 (LAG-3) glycoprotein, for the treatment of influenza virus in a subject. The inhibition of this interaction may be achieved by binding to HA and/or by binding to LAG-3, e.g., by an antibody that binds specifically to the domain in LAG-3 that interacts with HA. The present invention also provides an antibody, or an antibody fragment thereof comprising at least the antigen binding portion, which specifically binds to an N- glycosylation site within human LAG-3, and use of the antibody or fragment thereof in treatment of a disease selected from cancer, autoimmune disease, inflammatory disease and a CNS disease.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Meiri, David
Cohen, Vered
Abrégé
The present invention provides a pharmaceutical composition including one or more cannabinoids, and methods of using same, such as for treating estrogen receptor-related diseases. The present invention further provides combination therapy comprising one or more cannabinoids and an estrogen receptor activation inhibitor and use thereof in sensitizing subjects that are resistance to treatment with the estrogen receptor activation inhibitor alone.
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Saliba, Walaa
Zohar, Orr
Abrégé
The present invention provides a composite material and a sensing platform unit comprising a self-healing polymer matrix and at least two conductive nanomaterials embedded therein. The polymer matrix has a multi-layer structure comprising a first layer comprising a network of a first nanomaterial, which resistance changes in response to a mechanical damage inflicted on the polymer matrix; and a second layer comprising a network of a second nanomaterial, configured to generate heat under applied voltage. The network of the first nanomaterial and the network of the second nanomaterial are electrically connected to a mutual control circuit which is configured to apply voltage to the second nanomaterial upon a change in resistance of the first nanomaterial. The sensing platform unit further comprises a third layer comprising a network of a third nanomaterial configured to detect at least one of pressure, strain, temperature, pH, humidity, and volatile organic compounds (VOCs).
C08J 7/044 - Formation de revêtements conducteursFormation de revêtements ayant des propriétés antistatiques
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Haick, Hossam
Einoch Amor, Reef
Broza, Yoav
Abrégé
The present invention provides methods of diagnosing cancer in a test subject, comprising exposing an array of chemically sensitive sensors comprising a material selected from the group consisting of conductive nanostructures coated with an organic coating, a conducting polymer and a conductive polymer composite, to a blood sample and a urine sample obtained from the test subject, and analyzing output signals of the chemically sensitive sensors upon exposure of the array to the blood sample and the urine sample. The array of the chemically sensitive sensors can be a part of a portable medical device. Further provided is a method of diagnosing cancer in a test subject, comprising measuring and analyzing levels of a set of volatile organic compounds (VOCs) in a blood sample and a urine sample obtained from the test subject.
G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
14.
DEVICE, SYSTEMS, KITS AND METHODS FOR RAPID AND SIMPLE DETECTION OF PATHOGENS
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Geva-Zatorsky, Naama
Ben-Assa, Nadav
Naddaf, Rawi
Gefen, Tal
Abrégé
The present disclosure provides devices, systems, kits and methods for rapid, simple self-sampling and self-performing detection of nucleic acid sequence of interest in a sample, specifically, nucleic acid sequences of pathogenic agents.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
B01L 7/00 - Appareils de chauffage ou de refroidissementDispositifs d'isolation thermique
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
15.
TERNARY DUMBBELL NANOWIRE SEMICONDUCTORS FOR PHOTOCATALYSIS AND METHODS OF USE
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (Israël)
THE IP LAW FIRM OF GUY LEVI ()
Inventeur(s)
Amirav, Lilac
Chen, Yuexing
Abrégé
The disclosure relates to ternary dumb bell-shaped nanowire semiconductors for photocatalysis. Specifically, the disclosure relates to ternary dumbbell-shaped nanowire (TDNWs) semiconductors symmetrically decorated with a core-shell co-catalyst for photocatalys, methods for synthesis thereof and methods for generating hydrogen using the TDNWs.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Meiri, David
Besser, Elazar
Lewitus, Gil Moshe
Berman, Paula
Abrégé
The present invention provides a pharmaceutical composition including one or more cannabinoids, and methods of using same, such as for treating NOTCH-related diseases.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (Israël)
Inventeur(s)
Amirav, Lilac
Yedidya, Lior
Abrégé
Disclosed, in various exemplary implementations, are systems and methods for water photocatalysis using shaped semiconductor (or photo-induced charge carriers) immobilized on optionally removable transparent membranes under a closed redox cycle. Provided herein is a system for continuously generating hydrogen; a pressurized water source in continuous liquid communication with a first inlet; a pressurized source of an electron donor compound; and at least one removable transparent membrane comprising a plurality of at least partially embedded shaped nanoscale semiconductors, each having a basal end and an apical end, with a seed embedded within the shaped nanoscale semiconductors at the basal end, and a metal tip disposed at the apical end of the shaped nanoscale semiconductors.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Yehezkeli, Omer
Cohen, Roy
Cohen, Yifat
Mukah, Dina
Abrégé
The invention disclosed herein concerns an amperometric enzyme-based biosensor which exhibits high accuracy, high bioelectrocatalytic currents, linear response, low overpotentials and stability.
Technion Research and Development Foundation Limited (Israël)
Ramot At Tel-Aviv University Ltd. (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Offen, Daniel
Perets, Nisim
Abrégé
The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
C25B 9/13 - Cellules électrolytiques individuelles avec circulation d’un électrolyte
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
C25B 9/30 - Cellules ou assemblages de cellules comprenant des électrodes mobiles, p. ex. des électrodes rotativesAssemblages de leurs éléments de structure
C25B 9/40 - Cellules ou assemblages de cellules comprenant des électrodes constituées de particulesAssemblages de leurs éléments de structure
C25B 15/08 - Alimentation ou vidange des réactifs ou des électrolytesRégénération des électrolytes
22.
PEPTIDIC WATER-SOLUBLE DELIVERY SYSTEM OF ANTICANCER DRUGS
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
GATE2BRAIN, S.L. (Espagne)
Inventeur(s)
Montero Carcaboso, Ángel
Dario Sosnik, Alejandro
Resa Parés, Clàudia
Teixidó Turá, Meritxell
Abrégé
Micelles of peptidic conjugates of SN-38 loaded with one or more free therapeutic active agents which anticancer activity,such as free SN-38 lactone, process for their preparation, pharmaceutical compositions comprising them, and their therapeutical indications as anticancer drugs.
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Debbi, Lior
Abrégé
The present invention provides methods and systems for enhanced production and/or secretion of extracellular vesicles (EVs) from muscle cells utilizing various dynamic mechanical loading profiles thereon, cultured on three-dimensional (3D) scaffolds. The scaffolds may comprise a plurality of layers, wherein each layer comprises a plurality of elastic microfibers, and wherein the microfibers are aligned in parallel to a longitudinal axis and to each other. The elastic 3D scaffold may be configured to undergo dynamic mechanical loading profiles and support an expansion of a population of muscle cells cultured thereon into a 3D multi-layer structure of muscle cells, wherein said 3D multi-layer structure is configured to produce and/or secret extracellular vesicles into a medium.
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Cukurel, Beni
Abrégé
A novel structural arrangement for the various components of an Ultra-Micro Gas Turbine Generator, based on a single part impeller element which comprises the compressor, the turbine and the electrical generator core in a single annular structure, produced as a single piece by an additive manufacturing process. The single annular structure has a hollow shell structure, with a supporting structure within in. The internal hollow space of the shell structure provides for a flow of cooling air from the outside through the internal space, for cooling the turbine region of the impeller. This air flow could be assisted by the use of internal blades, which can also serve as the supporting structure to increase the strength of the shell structure. The air flow can either be ejected at the center of the turbine, or can provide a high pressure supply for air bearings of the impeller element.
F02C 3/045 - Ensembles fonctionnels de turbines à gaz caractérisés par l'utilisation de produits de combustion comme fluide de travail ayant une turbine entraînant un compresseur les passages du compresseur et de la turbine se trouvant sur un même rotor
F01D 15/10 - Adaptations pour la commande des générateurs électriques ou combinaisons avec ceux-ci
F02K 1/00 - Ensembles fonctionnels caractérisés par la forme ou la disposition de la tubulure de jet ou de la tuyèreTubulures de jet ou tuyères particulières à cet effet
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Sarkar, Tanmoy
Frey, Gitti L.
Abrégé
A transistor structure is presented comprising: an organic semiconductor channel region, and source and drain electrodes in electrical contact with said organic semiconductor channel region, wherein at least one of said source and drain electrodes is formed by spaced apart regions of a first metallic material separated by regions of a second metallic material such that regions of the first and second metallic materials are in contact with the organic semiconductor channel region, said first metallic material being selected as having work function substantially similar to HOMO energy level of said organic semiconductor channel region and said second metallic material being selected as having work function substantially similar to LUMO energy level of said organic semiconductor channel region, thereby enabling selective injections of electrons or holes into said channel region.
H10K 10/46 - Transistors à effet de champ, p. ex. transistors organiques à couche mince [OTFT]
H10K 19/10 - Dispositifs intégrés, ou ensembles de plusieurs dispositifs, comprenant au moins un élément organique spécialement adapté au redressement, à l'amplification, à l'oscillation ou à la commutation couvert par le groupe . comprenant des transistors à effet de champ
A laser source is presented a plurality of unit cells of a selected number of partially physically coupled lasing units arranged within a plane and configured to form a topological structure, wherein each of the lasing units is configured to emit radiation component substantially perpendicular to said plane, said plurality of the unit cells comprising at least a first sub-array of the unit cells located in a first region interfacing with a second region of a different type than said first region, thereby defining an arrangement of optically coupled lasing units along an interface region between the first and second adjacent regions, forming at least one topological state along a topological path within said interface region.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Meiri, David
Aviram, Joshua
Abrégé
The present invention relates to pharmaceutical compositions containing certain phytocannabinoids and their use in treating or preventing headaches, particularly migraine headaches.
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Tang, Ning
Abrégé
The present invention provides a self-healing biocompatible elastomer comprising polymeric chains comprising units of formula (Al), wherein R1 is selected from the group consisting of a linear (C2-C20) alkylene and — R4-S-S- R4' —, wherein R4 and R4' are independently a linear (C1-C10) alkylene; R2 is a linear or cyclic (C4-C10) alkylene; and R3 is selected from the group consisting of a polybutadiene, a polybutene, a polyethylene, a polypropylene, and a polyisoprene, wherein the elastomer is crosslinked by hydrogen bonds between urethane linkages. Further provided is a one-pot method for preparing a self- healing biocompatible elastomer. The invention further provides an antibacterial composition and a wound dressing comprising the self-healing biocompatible elastomer. Formula (A1)
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
C08G 18/75 - Polyisocyanates ou polyisothiocyanates cycliques cycloaliphatiques
C09D 175/14 - Polyuréthanes comportant des liaisons non saturées carbone-carbone
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
NANOSE MEDICAL LTD (Israël)
Inventeur(s)
Haick, Hossam
Marom Albeck, Orit
Sella Tavor, Osnat
Abrégé
The invention proposes an approach utilizing novel and artificially intelligent hybrid sensor arrays with multiplexed detection capabilities for disease-specific biomarkers from the exhaled breath of a subject. The technology provides a rapid and highly accurate diagnosis in various COVID-19 infection and transmission scenarios.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
30.
WEARABLE MICRONEEDLES-BASED EXTENDED GATE FIELD-EFFECT TRANSISTOR FOR REAL-TIME DETECTION OF BIOMARKERS FROM INTERSTITIAL FLUID
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Zheng, Youbin
Omar, Rawan
Saliba, Walaa
Abrégé
The present disclosure provides a device and system for detecting and/or measuring a constituent of an interstitial fluid from the skin of a subject. The device is a wearable extended gate field effect transistor (EGFET) device comprising a polymeric substrate for fixing to the skin of the subject; an extended gate electrode comprising a first microneedle configured for accessing the interstitial fluid and a first electric contact, wherein the first microneedle and the first electric contact are disposed on the polymeric substrate; and a field effect transistor (FET) associated with the first microneedle through the first electric contact. Further provided are a method for detecting and/or measuring a constituent of an interstitial fluid from the skin of a subject involving the use of the system and a method for fabricating the EGFET device.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Abrégé
A self-healing field-effect transistor (FET) device is disclosed in this application, the self-healing FET has a self-healing substrate, a self-healing dielectric layer, a gate electrode, at least one source electrode, at least one drain electrode, and at least one channel. The self-healing substrate and the self-healing dielectric layer have a disulfide-containing poly(urea-urethane) (PUU) polymer. The self-healing dielectric layer has a thickness of less than about 10 μm. The electrodes have electrically conductive elongated nanostructures. The at least one channel has semi-conducting elongated nanostructures.
H01L 29/78 - Transistors à effet de champ l'effet de champ étant produit par une porte isolée
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
H01L 29/24 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des matériaux semi-conducteurs inorganiques non couverts par les groupes , , ou
H01L 29/423 - Electrodes caractérisées par leur forme, leurs dimensions relatives ou leur disposition relative ne transportant pas le courant à redresser, à amplifier ou à commuter
H01L 29/66 - Types de dispositifs semi-conducteurs
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Suss, Matthew E.
Asokan, Arunchander
Abu Khalla, Shada
Abrégé
The present invention provides a non-biological deionization fuel cell (DFC) comprising, inter alia, a cathode comprising a non-platinum group metal and a nitrogen doped carbon matrix. Further provided is a method of preparing the catalyst through a zeolitic imidazolate framework precursor.
C02F 1/46 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques
C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse
C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
H01M 8/08 - Éléments à combustible avec électrolytes aqueux
H01M 8/22 - Éléments à combustible dans lesquels le combustible est à base de matériaux comprenant du carbone, de l'oxygène ou de l'hydrogène et d'autres élémentsÉléments à combustible dans lesquels le combustible est à base de matériaux comprenant uniquement des éléments autres que le carbone, l'oxygène ou l'hydrogène
33.
Automatic classification of healthy and disease conditions from images or digital standard 12-lead ECGs
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Schuster, Yael Yaniv
Schuster, Assaf
Gliner, Vadim
Abrégé
A method for automatic determining of a state of a heart of a patient based on multiple-lead ECG information of the patient, the method includes (a) receiving the multiple-lead ECG information of the patient, by a computerized system; and (b) applying one or more machine learning processes on the multiple-lead ECG information of the patient to determine the state of a heart of the patient, wherein the state of the heart comprises at least one heart condition of multiple types of heart conditions. One, some or all of the one or more machine learning processes was trained using a dataset that comprises multiple computer generated images, the multiple computer generated images represent images acquired by an image acquisition process of ECG plots, wherein the ECG plots are generated based on digital multiple-lead ECG signals.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Sabary, Omer
Shapira, Guy
Yaakobi, Eitan
Yucovich, Alexander
Abrégé
There may be provided method for estimating an information unit represented by a cluster of traces that are noisy copies of a synthesized strand, the method may include estimating the information unit by applying processing operations on r-tuples related to the traces, wherein r is smaller than a number (t) of traces of the cluster; wherein processing operations applied on at least some of the r-tuples comprise calculating a length of a shortest common supersequences (SCS) of the r-tuples.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Anavy, Leon
Yakhini, Zohar
Amit, Roee
Abrégé
A molecular data storage system is presented for encoding data-block(s). The system includes one or more populations of molecular sequences, each population encoding a respective one of the data-blocks. Each molecular sequence comprises a data encoding section comprising a sequence of similar predetermined length N of short k-mers, whereby in each population the data encoding sections of all molecular sequences have the similar predetermined length N. The short k-mers serve as data encoding building blocks of the data encoding sections, whereby valid short k-mers serving as data encoding building blocks form a subset of a building-block-set consisting of a number Z of different preselected short k-mers each presenting a unique combination of a number k of bases of a preselected set of bases, characterized in that all the Z types of short k-mers in said building-block-set have a similar predetermined size k≥2 (plurality) of bases. The data encoding sections collectively encode a sequence of encoded alphabet letters S=(π1, π2, . . . , πn . . . , πN−1, πN). Each valid encoded alphabet letter πn at location n of the sequence S of alphabet letters is characterized by occurrence of a predetermined plurality of different types of short k-mers of the building-block-set in a corresponding location n along the data encoding sections of the plurality of molecular sequences of said population.
C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
C02F 1/58 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par élimination de composés spécifiés dissous
A01K 63/02 - Récipients spécialement conçus pour transporter le poisson vivant
A01K 63/04 - Agencements pour traiter l'eau spécialement conçus pour les récipients pour poissons vivants
B01J 20/02 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
C02F 1/44 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par dialyse, osmose ou osmose inverse
C02F 1/66 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par neutralisationAjustage du pH
C02F 3/04 - Procédés aérobies utilisant des filtres lents
C02F 3/06 - Procédés aérobies utilisant des filtres immergés
C02F 101/16 - Composés de l'azote, p. ex. ammoniac
C02F 103/08 - Eau de mer, p. ex. pour le dessalement
C02F 103/20 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter provenant de l'élevage d'animaux
37.
Scintillator structure and a method for emitting an output signal at a specific wavelength range
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Kaminer, Ido
Kurman, Yaniv
Dahan, Raphael
Beer, Orr
Abrégé
The present invention discloses a scintillator structure and to a method for producing an output optical signal at a specific wavelength range. The scintillator structure comprises a multilayer nanostructure formed by at least one pair of alternating first and second layered material being arranged along one or more principal axes. The multi-layer nanostructure defines predetermined geometrical parameters and the structure is made of at least two different material compositions. At least one of the first layered material, the second layered material, or the combination of both, define scintillation properties. The invention also discloses a detector system for detecting an input radiation comprising a scintillator structure being as defined above and being configured and operable to collect most of the emitted optical signal.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Berlin, Shai
Carmi, Ido
Zoabi, Shaden
Abrégé
Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
Carmel Haifa University Economic Corporation Ltd. (Israël)
Evogene Ltd. (Israël)
Elbit Systems Land and C4I Ltd. (Israël)
Hazera Seeds Ltd. (Israël)
Opgal Optronics Industries Ltd. (Israël)
Rahan Meristem (1998) Ltd. (Israël)
Sensilize Ltd. (Israël)
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (Israël)
Technion Research and Development Foundation Limited (Israël)
Inventeur(s)
Coen, Lior
Alchanatis, Victor
Markovich, Ohsry
Zur, Yoav
Koster, Daniel
Montekyo, Yogev
Karchi, Hagai
Leizerson, Ilya
Aloni, Sharone
Brook, Anna
Granevitze, Zur
Honen, Yaron
Zvirin, Alon
Kimmel, Ron
Abrégé
The present invention relates to the field of phenotyping, particularly to systems and methods for collecting, retrieval and processing of data for accurate and sensitive analysis and prediction of a phenotype of an object, particularly of a plant.
G01N 21/27 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en utilisant la détection photo-électrique
G01S 17/894 - Imagerie 3D avec mesure simultanée du temps de vol sur une matrice 2D de pixels récepteurs, p. ex. caméras à temps de vol ou lidar flash
G01S 17/86 - Combinaisons de systèmes lidar avec des systèmes autres que lidar, radar ou sonar, p. ex. avec des goniomètres
G01N 21/25 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
G06V 10/143 - Détection ou éclairage à des longueurs d’onde différentes
G06V 10/147 - Détails de capteurs, p. ex. lentilles de capteurs
G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
G06V 10/40 - Extraction de caractéristiques d’images ou de vidéos
G06T 7/30 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images
H04N 5/247 - Disposition des caméras de télévision
H04N 5/232 - Dispositifs pour la commande des caméras de télévision, p.ex. commande à distance
G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Tartakovsky, Leonid
Sheintuch, Moshe
Veinblat, Mark
Thawko, Andy
Abrégé
A thermochemical recuperation (TCR) system that may use a water-alcohol mixture as an engine liquid coolant; that may include a TCR reformer configured to output a TCR product at pressure no less than twenty bars; a pressure regulator; and an TCR product accumulator configured to separate an outputting of the TCR product by the TCR reformer from a provision of the TCR product to the pressure regulator; wherein the pressure regulator is configured to provide the TCR product to a direct injector of an engine, thereby enabling the direct injector to inject the TCR product at a high pressure level—for example at a pressure level that exceeds twenty bars.
F02M 21/02 - Appareils pour alimenter les moteurs en combustibles non liquides, p. ex. en combustibles gazeux stockés sous forme liquide en combustibles gazeux
F01P 3/20 - Circuits de refroidissement non spécifiques d'une pièce particulière des moteurs ou "machines"
F01P 5/10 - Pompage du liquide de refroidissementAménagements des pompes de refroidissement
F01P 3/02 - Disposition du refroidissement des cylindres ou des hauts de cylindres
F01P 7/16 - Commande du débit de l'agent de refroidissement l'agent de refroidissement étant un liquide par commande thermostatique
F01N 5/02 - Silencieux ou dispositifs d'échappement combinés ou associés à des dispositifs bénéficiant de l'énergie des gaz évacués les dispositifs utilisant la chaleur
F02G 5/02 - Utilisation de la chaleur perdue dans les gaz d'échappement
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Zohar, Barak
Debbi, Lior
Abrégé
The present invention provides stem cells-derived extracellular vesicles (EVs) characterized by upregulation and/or downregulation of specific proteins. Composition comprising the EVs, and their use in the treatment of diseases and disorders associated with the upregulated proteins are also provided.
A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Abrégé
The present invention provides a solution-processable self-healing hydrolytically stable elastomer, a method for the preparation thereof, and articles of manufacture comprising the elastomer. The elastomer comprises polymeric chains comprising units of formula (A1), wherein R is a polybutadiene-containing polyurethane; R1 and R1′ are independently selected from the group consisting of: —H, (C1-C20)alkyl, (C5-C14)aryl, —OR4, —(CO)R5, —O(CO)R6, —(SO)R7, CO—R8, —COOR9, —NO2, and halogen; R2, R2′, R3 and R3′ are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; R4 to R9 are the same or different, and are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; m is 4; wherein the elastomer is dynamically crosslinked by aromatic disulfide metathesis, and wherein the elastomer has a water contact angle of above 100 #.
The present invention provides a solution-processable self-healing hydrolytically stable elastomer, a method for the preparation thereof, and articles of manufacture comprising the elastomer. The elastomer comprises polymeric chains comprising units of formula (A1), wherein R is a polybutadiene-containing polyurethane; R1 and R1′ are independently selected from the group consisting of: —H, (C1-C20)alkyl, (C5-C14)aryl, —OR4, —(CO)R5, —O(CO)R6, —(SO)R7, CO—R8, —COOR9, —NO2, and halogen; R2, R2′, R3 and R3′ are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; R4 to R9 are the same or different, and are independently selected from the group consisting of: —H, (C1-C20)alkyl, and (C5-C14)aryl; m is 4; wherein the elastomer is dynamically crosslinked by aromatic disulfide metathesis, and wherein the elastomer has a water contact angle of above 100 #.
G01L 1/22 - Mesure des forces ou des contraintes, en général en mesurant les variations de la résistance ohmique des matériaux solides ou des fluides conducteurs de l'électricitéMesure des forces ou des contraintes, en général en faisant usage des cellules électrocinétiques, c.-à-d. des cellules contenant un liquide, dans lesquelles un potentiel électrique est produit ou modifié par l'application d'une contrainte en utilisant des jauges de contrainte à résistance
G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
43.
PASTE COMPRISING AMORPHOUS CALCIUM CARBONATE AND DRY 3D MODELS PREPARED THEREFROM
Technion Research and Development Foundation Ltd (Israël)
Inventeur(s)
Pokroy, Boaz
Shaked, Hadar
Polishchuk, Iryna
Abrégé
The present invention relates to a paste comprising amorphous calcium carbonate (ACC) doped with divalent alkaline-earth metal ions, e.g., magnesium ions, or transition metal ions: a dry three-dimensional model made of such a paste, e.g., by 3D-printing process such as robocasting 3D-printing process; and a process for the preparation of said paste.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Meiri, David
Cohen, Vered
Abrégé
The present invention provides a pharmaceutical composition including one or more cannabinoids, and methods of using same, such as for treating estrogen receptor-related diseases. The present invention further provides combination therapy comprising one or more cannabinoids and an estrogen receptor activation inhibitor and use thereof in sensitizing subjects that are resistance to treatment with the estrogen receptor activation inhibitor alone.
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61K 31/138 - Aryloxyalkylamines, p. ex. propranolol, tamoxifène, phénoxybenzamine
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Einoch Amor, Reef
Broza, Yoav
Abrégé
The present invention provides methods of diagnosing cancer in a test subject, comprising exposing an array of chemically sensitive sensors comprising a material selected from the group consisting of conductive nanostructures coated with an organic coating, a conducting polymer and a conductive polymer composite, to a blood sample and a urine sample obtained from the test subject, and analyzing output signals of the chemically sensitive sensors upon exposure of the array to the blood sample and the urine sample. The array of the chemically sensitive sensors can be a part of a portable medical device. Further provided is a method of diagnosing cancer in a test subject, comprising measuring and analyzing levels of a set of volatile organic compounds (VOCs) in a blood sample and a urine sample obtained from the test subject.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Saliba, Walaa
Zohar, Orr
Abrégé
The present invention provides a composite material and a sensing platform unit comprising a self-healing polymer matrix and at least two conductive nanomaterials embedded therein. The polymer matrix has a multi-layer structure comprising a first layer comprising a network of a first nanomaterial, which resistance changes in response to a mechanical damage inflicted on the polymer matrix; and a second layer comprising a network of a second nanomaterial, configured to generate heat under applied voltage. The network of the first nanomaterial and the network of the second nanomaterial are electrically connected to a mutual control circuit which is configured to apply voltage to the second nanomaterial upon a change in resistance of the first nanomaterial. The sensing platform unit further comprises a third layer comprising a network of a third nanomaterial configured to detect at least one of pressure, strain, temperature, pH, humidity, and volatile organic compounds (VOCs).
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
Technion Research and Development Foundation, Ltd. (Israël)
Inventeur(s)
Levenberg, Shulamit
Stauber, Hagit
Avesar, Jonathan
Abrégé
A device comprising: plurality of Stationary Nanoliter Droplet Array (SNDA) components; each SNDA component comprising: at least one primary channel; at least one secondary channel; and a plurality of nano-wells that are each open to the primary channel and are each connected by one or more vents to the secondary channel; the vents are configured to enable passage of air solely from the nano-wells to the secondary channel, such that when a liquid is introduced into the primary channel it fills the nano-wells, and the originally accommodated air is evacuated via the vents and the secondary channel/s; an inlet port and a distribution channel configured to enable a simultaneous introduction of the liquid into all primary channels; and an outlet port and an evacuation channel configured to enable a simultaneous evacuation of the air out of all the secondary channels.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Nazarathy, Moshe
Abrégé
An optical digital to analog converter (oDAC) that may include (a) multiple optical paths that are parallel to each other; (b) a combiner, (c) a splitter that is configured to receive an optical signal at a splitter input and split the optical signal between multiple splitter outputs to provide multiple path input signals to the multiple optical paths. The multiple optical paths are configured to optically process, in parallel, path input signals to provide path output signals. Each optical path is configured to apply an optical process that comprises applying optical modulation, by an optical gate of the optical path and under a control of an electrical modulator, to provide an optical signal having a value selected out of multiple constellation levels. The combiner is configured to add the multiple path output signals to provide an oDAC output signal having a value selected from values of a single quadrature constellation.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Meiri, David
Besser, Elazar
Lewitus, Gil Moshe
Berman, Paula
Abrégé
The present invention provides a pharmaceutical composition including one or more cannabinoids, and methods of using same, such as for treating NOTCH-related diseases.
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Yelin, Dvir
Hamra, Matan
Abrégé
in vivo in vivo functional imaging of the human ear and measurement of nanometer scale motion of the tympanic membrane under various acoustic excitations, and identification of vibration patterns that vary between human subjects in response to sound. By combining spectrally encoded imaging with phase-sensitive spectral-domain interferometry, high-resolution imaging of the membrane surface is obtained within a fraction of a second, through a handheld imaging probe. The detailed physiological data obtained allows measuring a wide range of clinically relevant parameters for patient diagnosis, and provides a new tool for studying middle and inner ear physiology. Use of a line measurement technique, without mechanically scanning the probe beam, enables characteristics of the membrane vibration to be measured, in a time scale of tenths of a second, thereby reducing the possibility of inaccuracy because of movements of the hand-held instrument.
A61B 1/227 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour les oreilles, c.-à-d. otoscopes
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Elbaz, Shai
Salem, Lior
Gamus, Benny
Or, Yizhar
Gat, Amir
Peretz, Ofek
Abrégé
An airfoil surface skin, comprising a network of a solid material, embedded in a base of deformable solid material. Fluid pressure applied to the interface between the network and the surrounding embedding material, opens an internal network of channels by viscous peeling of the surrounding solid from the network. The network is offset from the centerline the surround material, such that pressure driven viscous flow through the narrow channels generates two types of deformation of the skin—an in-plane elongation and a curvature of the skin plane itself. The shape of the internal solid core element and its material, and the material of the encompassing solid are chosen to achieve a desired integral structural rigidity. The injected fluid pressure determines the extent of extension and bending. Use of this skin enables shape amending airfoils having reduced drag compared with similar airfoils having conventional flap mechanisms.
C25B 11/075 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’un seul élément catalytique ou composé catalytique
B01J 21/00 - Catalyseurs contenant les éléments, les oxydes ou les hydroxydes du magnésium, du bore, de l'aluminium, du carbone, du silicium, du titane, du zirconium ou du hafnium
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Wu, Weiwei
Abrégé
The present invention provides a vapor-permeable flexible sensing platform unit comprising: a first porous membrane, wherein said membrane is substantially flexible and hydrophobic; and a volatile organic compounds (VOCs) sensor disposed on said membrane, the VOCs sensor comprising an electrode array and a conducting polymer porous film being in electric contact with said electrode array, wherein the VOCs sensor is insensitive to lateral strain. Further provided are a method of preparation of said platform unit and a lift-off, float-on (LOFO) method for the preparation of protonically doped polyaniline (PANI) thin films.
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
G01K 7/18 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs l'élément étant une résistance linéaire, p. ex. un thermomètre à résistance de platine
G01L 19/00 - Détails ou accessoires des appareils pour la mesure de la pression permanente ou quasi permanente d'un milieu fluent dans la mesure où ces détails ou accessoires ne sont pas particuliers à des types particuliers de manomètres
G01N 33/497 - Analyse physique de matériau biologique de matériau biologique gazeux, p. ex. de l'haleine
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Yehezkeli, Omer
Cohen, Roy
Cohen, Yifat
Mukah, Dina
Abrégé
The invention dislosed herein concerns an amperometric enzyme-based biosensor which exhibits high accuracy, high bioelectrocatalytic currents, linear response, low overpotentials and stability.
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Shomron, Gil
Weiser, Uri
Abrégé
A method for non-blocking multithreading, the method may include (a) providing, during a deep neural network (DNN) calculation iteration, to a shared computational resource, input information units related to multiple DNN threads; (b) determining whether to reduce a numerical precision of one or more DNN calculations related to at least one of the multiple DNN threads, and (c) executing, based on the determining, DNN calculations on at least some of the input information units to provide one or more results of the DNN processing.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Debbi, Lior
Abrégé
The present invention provides methods and systems for enhanced production and/or secretion of extracellular vesicles (EVs) from muscle cells utilizing various dynamic mechanical loading profiles thereon, cultured on three-dimensional (3D) scaffolds. The scaffolds may comprise a plurality of layers, wherein each layer comprises a plurality of elastic microfibers, and wherein the microfibers are aligned in parallel to a longitudinal axis and to each other. The elastic 3D scaffold may be configured to undergo dynamic mechanical loading profiles and support an expansion of a population of muscle cells cultured thereon into a 3D multi-layer structure of muscle cells, wherein said 3D multi- layer structure is configured to produce and/or secret extracellular vesicles into a medium.
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Grader, Gideon
Rothschild, Avner
Dotan, Hen
Landman, Avigail
Kay, Asaf
Moshkovich, Mordechay
Abrégé
The invention provides a system for continuous generation of gases, the system comprising an electrochemical device and an active- material regeneration device.
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
C25B 9/21 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes avec plusieurs diaphragmes
C25B 9/30 - Cellules ou assemblages de cellules comprenant des électrodes mobiles, p. ex. des électrodes rotativesAssemblages de leurs éléments de structure
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Grader, Gideon
Rothschild, Avner
Dotan, Hen
Landman, Avigail
Kay, Asaf
Moshkovich, Mordechay
Abrégé
The invention provides a system for continuous generation of gases, the system comprising an electrochemical device and an active- material regeneration device.
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
C25B 9/21 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes avec plusieurs diaphragmes
C25B 9/30 - Cellules ou assemblages de cellules comprenant des électrodes mobiles, p. ex. des électrodes rotativesAssemblages de leurs éléments de structure
C25B 9/75 - Assemblages comprenant plusieurs cellules du type filtre-presse avec une électrode bipolaire
C25B 9/77 - Assemblages comprenant plusieurs cellules du type filtre-presse avec diaphragmes
C25B 15/02 - Commande ou régulation des opérations
59.
TYROSINE, TRYPTOPHAN AND PHENYLALANINE AS mTOR AGONISTS MEDIATING PROTEASOME DYNAMICS, COMPOSITIONS, METHODS AND USES THEREOF IN THERAPY, AND PROGNOSTIC METHODS FOR DRUG-RESISTANCE
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
RAMBAM MED-TECH LTD. (Israël)
Inventeur(s)
Livneh, Ido
Cohen-Kaplan, Victoria
Ciechanover, Aaron
Goldhirsh, Gilad
Zohar, Yaniv
Lavi, Noa
Fabre, Bertrand Francois
Abrégé
The present disclosure provides mTOR agonists that selectively modulate proteasome dynamics, compositions, methods and uses thereof for modulation of stress-induced proteasome dynamics and related pathological conditions. The present disclosure specifically provides therapeutic methods for treating disorders associated with cytosolic accumulation of the proteasome. The invention further provides prognostic methods for detection and monitoring drug resistant cancers, as well as methods for screening for modulators of proteasome dynamics.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
60.
TYROSINE, TRYPTOPHAN AND PHENYLALANINE AS MTOR AGONISTS MEDIATING PROTEASOME DYNAMICS, COMPOSITIONS, METHODS AND USES THEREOF IN THERAPY, AND PROGNOSTIC METHODS FOR DRUG-RESISTANCE
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
RAMBAM MED-TECH LTD. (Israël)
Inventeur(s)
Livneh, Ido
Cohen-Kaplan, Victoria
Ciechanover, Aaron
Goldhirsh, Gilad
Zohar, Yaniv
Lavi, Noa
Fabre, Bertrand Francois
Abrégé
The present disclosure provides mTOR agonists that selectively modulate proteasome dynamics, compositions, methods and uses thereof for modulation of stress-induced proteasome dynamics and related pathological conditions. The present disclosure specifically provides therapeutic methods for treating disorders associated with cytosolic accumulation of the proteasome. The invention further provides prognostic methods for detection and monitoring drug resistant cancers, as well as methods for screening for modulators of proteasome dynamics.
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Nemirovsky, Yael
Bar-Lev Shefi, Sharon
Brouk, Igor
Abrégé
There may be provided a radiation sensing device that includes a first TMOS with temperature dependent electrical parameters; wherein the first TMOS is exposed to radiation, and a second TMOS transistor that is sheltered from radiation. The radiation sensing device performs a differential measurement, and applied various measures for noise reduction, and maintaining the stability of the radiation sensing device.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Meiri, David
Aviram, Joshua
Abrégé
The present invention relates to pharmaceutical compositions containing certain phytocannabinoids and their use in treating or preventing headaches, particularly migraine headaches.
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Nazarathy, Moshe
Agmon, Amos
Tolmachev, Alexander
Abrégé
An electro-optic system, the electro-optic system that may include an input port that is configured to receive a bandpass signal that conveys information; wherein the bandpass signal is a radio frequency (RF) signal; an optical carrier source that is configured to generate an optical carrier signal having an optical carrier frequency; at least one electrical bias circuit that is configured to generate at least one electrical bias signal; an electro-optic modulation circuit that is linear at the optical field; a manipulator that is configured to (a) receive the at least one electrical bias signal and the bandpass signal, (b) generate, based on the at least one electrical bias signal and the bandpass signal, at least one modulating signal; wherein the electro-optic modulation circuit is configured to modulate the optical carrier by the at least one modulating signal to provide an output optical signal that comprises at least one optical pilot tone and at least one optical sideband that conveys the information.
G02B 6/293 - Moyens de couplage optique ayant des bus de données, c.-à-d. plusieurs guides d'ondes interconnectés et assurant un système bidirectionnel par nature en mélangeant et divisant les signaux avec des moyens de sélection de la longueur d'onde
G02B 6/28 - Moyens de couplage optique ayant des bus de données, c.-à-d. plusieurs guides d'ondes interconnectés et assurant un système bidirectionnel par nature en mélangeant et divisant les signaux
G02B 6/42 - Couplage de guides de lumière avec des éléments opto-électroniques
64.
DEVICE, SYSTEMS, KITS AND METHODS FOR RAPID AND SIMPLE DETECTION OF PATHOGENS
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Geva-Zatorsky, Naama
Ben-Assa, Nadav
Naddaf, Rawi
Gefen, Tal
Abrégé
The present disclosure provides devices, systems, kits and methods for rapid, simple self-sampling and self-performing detection of nucleic acid sequence of interest in a sample, specifically, nucleic acid sequences of pathogenic agents.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12Q 1/6865 - Amplification à base de promoteurs, p. ex. amplification de séquence d’acide nucléique [NASBA], système de réplication de séquence auto-entretenue [3SR] ou d’amplification à base de transcription [TAS]
A laser source is presented a plurality of unit cells of a selected number of partially physically coupled lasing units arranged within a plane and configured to form a topological structure, wherein each of the lasing units is configured to emit radiation component substantially perpendicular to said plane, said plurality of the unit cells comprising at least a first sub-array of the unit cells located in a first region interfacing with a second region of a different type than said first region, thereby defining an arrangement of optically coupled lasing units along an interface region between the first and second adjacent regions, forming at least one topological state along a topological path within said interface region.
H01S 5/183 - Lasers à émission de surface [lasers SE], p. ex. comportant à la fois des cavités horizontales et verticales comportant uniquement des cavités verticales, p. ex. lasers à émission de surface à cavité verticale [VCSEL]
H01S 5/40 - Agencement de plusieurs lasers à semi-conducteurs, non prévu dans les groupes
66.
METHOD FOR SELECTIVE SEPARATION OF IONIC SPECIES FROM IONIC SOLUTION BASED ON IONIC HYDRATED SIZE
TECHION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Suss, Matthew
Guyes, Eric
Chen, Yinke
Uwayid, Rana
Abrégé
The present invention relates to methods for selective separation of ionic species from an ionic solution based on said species' ionic hydrated size, the method comprising, inter alia, passing an ionic solution comprising ions having distinct hydrated sizes, through an electrode capacitor assembly comprising at least one carbon-based electrode which is modified with negatively or positively charged surface groups. Further provided is a method for selective separation of ionic species from an ionic solution comprising passing the ionic solution comprising a first positively charged ion and a second positively charged in through an electrode capacitor assembly, wherein the first modified electrode comprises carbon modified with sulfonate surface groups.
C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
H01G 11/32 - Électrodes caractérisées par leur matériau à base de carbone
H01G 11/26 - Électrodes caractérisées par leur structure, p. ex. multicouches, selon la porosité ou les caractéristiques de surface
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
NANOSE MEDICAL LTD (Israël)
Inventeur(s)
Haick, Hossam
Marom Albeck, Orit
Sella Tavor, Osnat
Abrégé
The invention proposes an approach utilizing novel and artificially intelligent hybrid sensor arrays with multiplexed detection capabilities for disease-specific biomarkers from the exhaled breath of a subject. The technology provides a rapid and highly accurate diagnosis in various COVID-19 infection and transmission scenarios.
G01N 33/497 - Analyse physique de matériau biologique de matériau biologique gazeux, p. ex. de l'haleine
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
A61B 5/083 - Mesure du taux de métabolisme en utilisant un essai respiratoire, p. ex. mesure du taux de consommation d'oxygène
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Gido, Ben
Broday, David
Friedler, Eran
Abrégé
A system for extracting water from the atmosphere is disclosed. The system has a vapor absorber vessel, an absorption cycle pump, a flash drum vapor desorber, a vapor condenser, an output conduit, and a heat exchanger. The vessel has an atmospheric air inlet and outlet ports, at least one liquid desiccant inlet port, at least two liquid desiccant outlet ports, and a surface on which the liquid desiccant flows between the at least one liquid desiccant inlet port and the at least two liquid desiccant outlet ports. The pump is adapted to circulate a first portion of the liquid desiccant from a first of the outlet ports to the at least one inlet port. The desorber is adapted to receive a second portion of the liquid desiccant from a second of the outlet ports, after passage through an expansion valve, the desorber incorporates a heat exchanger for supplying heat to liquid desiccant therein. The condenser receives desorbed vapor from the desorber, the condenser incorporates condensation surfaces adapted to be cooled to a temperature of less than 20° C., for enabling the condensing of the desorbed vapor to water. The output conduit collects water condensed in the condenser. The heat exchanger is located such that it receives desorbed heated liquid desiccant from the desorber and transfers part of its sensible heat to vapor-charged liquid desiccant passing from the vessel to the desorber.
Technion Research and Development Foundation Limited (Israël)
Inventeur(s)
Haick, Hossam
Broza, Yoav
Serasanambati, Mamatha
Hashoul, Dina
Saliba, Walaa
Abrégé
The present invention provides methods of detecting cell-to-cell signaling in cancer cells and methods of diagnosing, prognosing and monitoring cancer comprising the use of volatile organic compounds, which are indicative of cell-to-cell signaling in cancer cells.
G01N 33/84 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des composés inorganiques ou le pH
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Cukurel, Beni
Abrégé
A novel structural arrangement for the various components of an Ultra-Micro Gas Turbine Generator, based on a single part impeller element which comprises the compressor, the turbine and the electrical generator core in a single annular structure, produced as a single piece by an additive manufacturing process. The single annular structure has a hollow shell structure, with a supporting structure within in. The internal hollow space of the shell structure provides for a flow of cooling air from the outside through the internal space, for cooling the turbine region of the impeller. This air flow could be assisted by the use of internal blades, which can also serve as the supporting structure to increase the strength of the shell structure. The air flow can either be ejected at the center of the turbine, or can provide a high pressure supply for air bearings of the impeller element.
F01D 1/16 - "Machines" ou machines motrices à déplacement non positif, p. ex. turbines à vapeur avec des moyens stationnaires de guidage de fluide de travail et un rotor à ailettes ou de structure analogue caractérisées par la présence à la fois d'étages à réaction et d'étages à action
F01D 25/16 - Aménagement des paliersSupport ou montage des paliers dans les stators
F01D 25/22 - Systèmes de lubrification utilisant un fluide énergétique ou un autre fluide gazeux comme lubrifiant
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Abrégé
The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 μm, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
H01L 29/24 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des matériaux semi-conducteurs inorganiques non couverts par les groupes , , ou
H01L 29/423 - Electrodes caractérisées par leur forme, leurs dimensions relatives ou leur disposition relative ne transportant pas le courant à redresser, à amplifier ou à commuter
H01L 29/66 - Types de dispositifs semi-conducteurs
72.
PRODUCTION OF EXTRACELLULAR VESICLES FROM STEM CELLS
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Zohar, Barak
Abrégé
The present invention provides methods and systems for enhanced production and/or secretion of extracellular vesicles from at least one three-dimensional porous scaffold having a population of stem cells cultured thereon, utilizing various shear stress conditions on a variety of stem cells.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Anavy, Leon
Yakhini, Zohar
Amit, Roee
Abrégé
A molecular data storage system is presented for encoding data-block(s). The system includes one or more populations of molecular sequences, each population encoding a respective one of the data-blocks. Each molecular sequence comprises a data encoding section comprising a sequence of similar predetermined length N of short k-mers, whereby in each population the data encoding sections of all molecular sequences have the similar predetermined length N. The short k-mers serve as data encoding building blocks of the data encoding sections, whereby valid short k-mers serving as data encoding building blocks form a subset of a building-block-set consisting of a number Z of different preselected short k-mers each presenting a unique combination of a number k of bases of a preselected set of bases, characterized in that all the Z types of short k-mers in said building-block-set have a similar predetermined size k≥2 (plurality) of bases. The data encoding sections collectively encode a sequence of encoded alphabet letters S = (π1, π2,..., πn..., πΝ-1, πΝ). Each valid encoded alphabet letter πn at location n of the sequence S of alphabet letters is characterized by occurrence of a predetermined plurality of different types of short k-mers of the building-block-set in a corresponding location n along the data encoding sections of the plurality of molecular sequences of said population.
G06N 3/12 - Agencements informatiques fondés sur des modèles biologiques utilisant des modèles génétiques
G16B 30/00 - TIC spécialement adaptées à l’analyse de séquences impliquant des nucléotides ou des aminoacides
H03M 13/19 - Correction d'une seule erreur sans utiliser les propriétés particulières des codes cycliques, p. ex. codes de Hamming, codes de Hamming étendus ou généralisés
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Anavy, Leon
Yakhini, Zohar
Amit, Roee
Abrégé
A data storage system and method are provided, as well as systems and methods for fabrication, and writing and reading of data therein. The data storage system includes at least one population of molecular sequences including chains of basic molecular building-blocks, and defining at least one respective data-block encoding data in the data storage system. The data of the data-block is encoded in a sequence S=(π1, π2, . . . , πk . . . , πK-1, πK) of encoded letters {πk} associated with an alphabet Σ≡{σm}|m=1 to M, which are encoded according to the types of basic molecular building-blocks appearing at k respective location along storage segments of the molecular sequences of the population. The molecular sequences include a number Z of different types of basic molecular building-blocks {En}|n=1 to Z, while the alphabet Σ has a size M strictly greater than the number Z of types of building-blocks. Each alphabet letter σm is associated with a vector {Pmn}|n=1 to Z indicative of occurrences of basic molecular building-block En of type n in the alphabet letter σm. Accordingly each encoded letter πk at location k in the storage segments of molecular sequences of the data-block/population, is mapped to a corresponding alphabet letter σm by determining a match between the occurrence of basic molecular building-blocks of different types at that locations k of the molecular sequences of the population, with the vector {Pmn}|n=1 to Z associated with the alphabet letter σm. In some implementations the component Pmn of the vector {Pmn}m|n=1 to Z associated with alphabet letter σm is indicative of a probability that a basic molecular building-block En of type n, 1≤n≤Z, appears at the location k of the storage segment of a molecular strand of the at least one population in case the letter πk encoded at that location k corresponds to the alphabet letter σm.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Kaminer, Ido
Kurman, Yaniv
Dahan, Raphael
Beer, Orr
Abrégé
The present invention discloses a scintillator structure and to a method for producing an output optical signal at a specific wavelength range. The scintillator structure comprises a multilayer nanostructure formed by at least one pair of alternating first and second layered material being arranged along one or more principal axes. The multi-layer nanostructure defines predetermined geometrical parameters and the structure is made of at least two different material compositions. At least one of the first layered material, the second layered material, or the combination of both, define scintillation properties. The invention also discloses a detector system for detecting an input radiation comprising a scintillator structure being as defined above and being configured and operable to collect most of the emitted optical signal.
G01T 1/20 - Mesure de l'intensité de radiation avec des détecteurs à scintillation
G01T 3/06 - Mesure de flux de neutrons avec des détecteurs à scintillation
G01N 23/00 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou
76.
X-RAY RADIATION SOURCE SYSTEM AND METHOD FOR DESIGN OF THE SAME
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Kaminer, Ido
Shentcis, Michael
Dahan, Raphael
Abrégé
nln2n2 layers of said second layer type generating a selected lattice periodicity of said layers. The lattice periodicity is selected such that said multilayered crystal structure responds to the charged particle beam of predetermined parameters by coherent emission of X-ray radiation having selected spectral content and emission direction.
G01N 23/04 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et formant des images des matériaux
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Shlomi, Tomer
Lee, Won Dong
Abrégé
The invention provides a method for treating cancer in which a level of reduced folate carrier (RFC) or folylpolyglutamate synthetase (FPGS) in cancer cells of the biopsy is determined. If the level of RFC or FPGS in the cancer cells is below a threshold value, the cancer is treated with an inhibitor of serine-hydroxymethyl-transferase (SHMT)1. If the level of RFC or FPGS in the cancer cells is above the threshold value, the cancer is treated with an inhibitor of SHMT2.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITTED (Israël)
RAMOT AT TEL-AVIV UNIVERSITY LTD. (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Offen, Daniel
Perets, Nisim
Abrégé
The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
79.
Purge system for closed-cycle absorption heat pumps
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Gommed, Khaled
Grossman, Gershon
Evron, Yigal
Abrégé
A high-efficiency, motorless purge system for closed-cycle absorption heat pumps, adapted for both absorption heat transformers and absorption chillers, using a series of valves to control the entry and exit of absorbent solution into a low-pressure, secondary absorption vessel. A small percentage of the total circulating solution is forced under pressure into the secondary absorption vessel via a spray nozzle, causing adiabatic absorption of absorbate vapor by the solution. Non-condensable gases accumulate in the secondary absorber until a certain vapor pressure is reached, upon which, gas, and possibly liquid, are transferred to an exhaust vessel having an exit vent for non-condensable gases. In an absorption chiller system, the secondary absorber has an internal heat exchanger to lower the temperature of the solution within, to facilitate the absorption process.
F25B 43/04 - Dispositions pour la séparation ou la purification des gaz ou des liquidesDispositions pour la vaporisation des résidus de fluides frigorigènes, p. ex. par la chaleur pour l'évacuation des gaz non condensables
F25B 15/06 - Machines, installations ou systèmes à sorption, à marche continue, p. ex. à absorption sans gaz inerte le frigorigène étant de la vapeur d'eau évaporée d'une solution salée, p. ex. bromure de lithium
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Tartakovsky, Leonid
Sheintuch, Moshe
Veinblat, Mark
Thawko, Andy
Abrégé
A thermochemical recuperation (TCR) system that may use a water-alcohol mixture as an engine liquid coolant; that may include a TCR reformer configured to output a TCR product at pressure no less than twenty bars; a pressure regulator; and an TCR product accumulator configured to separate an outputting of the TCR product by the TCR reformer from a provision of the TCR product to the pressure regulator; wherein the pressure regulator is configured to provide the TCR product to a direct injector of an engine, thereby enabling the direct injector to inject the TCR product at a high pressure level – for example at a pressure level that exceeds twenty bars.
F01N 5/02 - Silencieux ou dispositifs d'échappement combinés ou associés à des dispositifs bénéficiant de l'énergie des gaz évacués les dispositifs utilisant la chaleur
F02G 5/04 - Utilisation de la chaleur perdue dans les gaz d'échappement en combinaison avec d'autre chaleur perdue par les moteurs à combustion
F02M 25/12 - Appareils spécifiques conjugués aux moteurs pour ajouter des substances non combustibles ou de petites quantités de combustible secondaire, à l’air comburant, au combustible principal ou au mélange air-combustible ajoutant de l'acétylène, de l'hydrogène non en provenance de l'eau, de l'oxygène non en provenance de l'air ou de l'ozone les appareils comportant des moyens de produire de tels gaz
F02M 27/02 - Appareils pour traiter l'air comburant, le combustible ou le mélange air-combustible par catalyseurs, moyens électriques, magnétisme, rayonnement, ondes sonores ou moyens analogues par catalyseurs
82.
Method for manufacturing a nano-wire array and a device that comprises a nano-wire array
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Haick, Hossam
Assad, Ossama
Abrégé
A device having a nano-wire array and a method for manufacturing an array of nano-wires. The method includes spraying on a substrate droplets of a suspension that comprises nano-wires and at least a partially volatile solvent; and evaporating the at least partially volatile solvent of the droplets to form the array of nano-wires. At least one of the spraying and the evaporating comprises executing at least one aggregation reduction measure for limiting a formation of three dimensional aggregations of nano-wires on the substrate.
H01L 21/00 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de dispositifs à semi-conducteurs ou de dispositifs à l'état solide, ou bien de leurs parties constitutives
H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
B82Y 40/00 - Fabrication ou traitement des nanostructures
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Levenberg, Shulamit
Guo, Shaowei
Zohar, Barak
Abrégé
The present invention provides methods and systems for enhanced production and/or secretion of extracellular vesicles from at least one three-dimensional porous scaffold having a population of stem cells cultured thereon, utilizing various shear stress conditions on a variety of stem cells.
A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Cukurel, Beni
Abrégé
A system and method for determining the condition of a thermal barrier coating on a base metal component, comprising the use of an induction coil to input into the metallic base layer through the coating layer, a temporally varying heat waveform, and measuring the temperature of the coating surface layer resulting from the input of the heat waveform using a temperature sensor disposed close to the surface of the coating layer. A controller correlates a signal from the temporally varying output of the temperature sensor with a signal corresponding to the temporally varying heat waveform, to determine the phase angle between the signals. The controller uses a mathematical relationship between the phase angle and the frequency of the heat waveform to determine the thermal properties of the non- metallic coating. Both the thermal diffusivity and the barrier coating thickness can be accurately obtained by this method and apparatus.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Nemirovsky, Yael
Nemirovsky, Amikam
Melman, Shmuel
Abrégé
A method for sensing gas by a gas sensing device, the method may include generating, by a semiconductor temperature sensing element that is spaced apart from a gas reactive element and is thermally coupled to the gas reactive element, detection signals that are indicative of a temperature of the gas reactive element; wherein the gas reactive element and the semiconductor temperature sensing element are of microscopic scale; and processing, by a readout circuit of the gas sensing device, the detection signals to provide information about a gas that affected the temperature of the gas reactive element.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Wolf, Alon
Shaulian, Hadar
Abrégé
A robotic shoe which provides real-time feedback regarding forces acting on the foot of the user, in order to modify these forces in a corrective or diagnostic manner. The shoe comprises an insole equipped with embedded pressure sensors enabling it to continuously monitor the ground reaction forces (GRF) and the foot center of pressure (COP) while the user is standing, walking, and running. The insole COP and GRF readings are input to a programmable system that shifts the COP trajectory dynamically in a patient-specific manner via the robotic platform of the shoe. The robotic platform contains motors that control elements whose movement manipulates the forces acting on the foot and lower limb, resulting in modification of the GRF. Closed loop feedback enables a dynamic fit of an optimal COP. The COP and GRF information can be stored for analysis and diagnosis of gait and instability events accruing during locomotion.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Abrégé
1 11205144567892223 31205144 912051414)aryl; m is 4; wherein the elastomer is dynamically crosslinked by aromatic disulfide metathesis, and wherein the elastomer has a water contact angle of above 100⁰.
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
C08G 18/65 - Composés à bas poids moléculaire contenant un hydrogène actif avec des composés à haut poids moléculaire contenant un hydrogène actif
C08G 18/75 - Polyisocyanates ou polyisothiocyanates cycliques cycloaliphatiques
G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
88.
QUANTIFICATION OF RESPIRATORY EFFORT FROM HEMODYNAMIC MEASUREMENTS
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
PÉREZ PÉREZ, Eugenio (Mexique)
Inventeur(s)
Landesberg, Amir
Faingersh-Klebanov, Anna
Abrégé
A method for detecting or monitoring the respiratory or cardiac health of a patient, including: measuring any intravascular or intracardiac pressure (IVP) of a patient over a period of time, said IVP including a measured respiratory wave; defining the respiratory effort of the patient as a peak-to-peak amplitude of the respiratory wave; and using the respiratory effort to detect or monitor the respiratory and cardiac health of the patient by comparing the respiratory effort with a known respiratory effort value or by monitoring changes in the respiratory effort of the patient over another period of time.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (Israël)
Inventeur(s)
Nemirovsky, Yael
Nemirovsky, Amikam
Abrégé
There is provided a gas sensing device for sensing a certain gas that is associated with a certain spectral band, the gas sensing device may include a passive gas sensor that is configured to generate passive gas sensor detection signals that are responsive to the certain spectral band; a passive dummy sensor that is configured to generate passive dummy sensor detection signals that are indifferent to the certain spectral hand; and at least one circuit that is configured to detect a presence or absence of the certain gas within a certain volume that is located within the fields of view of the passive gas sensor and the passive dummy sensor based on a comparison between the passive gas sensor detection signals and the passive dummy sensor detection signals.
G01N 21/31 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Wu, Weiwei
Abrégé
The present invention provides a vapor-permeable flexible sensing platform unit comprising: a first porous membrane, wherein said membrane is substantially flexible and hydrophobic; and a volatile organic compounds (VOCs) sensor disposed on said membrane, the VOCs sensor comprising an electrode array and a conducting polymer porous film being in electric contact with said electrode array, wherein the VOCs sensor is insensitive to lateral strain. Further provided are a method of preparation of said platform unit and a lift-off, float-on (LOFO) method for the preparation of protonically doped polyaniline (PANI) thin films.
G01N 33/497 - Analyse physique de matériau biologique de matériau biologique gazeux, p. ex. de l'haleine
G01K 7/18 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs l'élément étant une résistance linéaire, p. ex. un thermomètre à résistance de platine
G01L 19/00 - Détails ou accessoires des appareils pour la mesure de la pression permanente ou quasi permanente d'un milieu fluent dans la mesure où ces détails ou accessoires ne sont pas particuliers à des types particuliers de manomètres
91.
MORPHING AIRCRAFT SKIN WITH EMBEDDED VISCOUS PEELING NETWORK
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Elbaz, Shai
Salem, Lior
Gamus, Benny
Or, Yizhar
Gat, Amir
Peretz, Ofek
Abrégé
An airfoil surface skin, comprising a network of a solid material, embedded in a base of deformable solid material. Fluid pressure applied to the interface between the network and the surrounding embedding material, opens an internal network of channels by viscous peeling of the surrounding solid from the network. The network is offset from the centerline the surround material, such that pressure driven viscous flow through the narrow channels generates two types of deformation of the skin - an in-plane elongation and a curvature of the skin plane itself. The shape of the internal solid core element and its material, and the material of the encompassing solid are chosen to achieve a desired integral structural rigidity. The injected fluid pressure determines the extent of extension and bending. Use of this skin enables shape amending airfoils having reduced drag compared with similar airfoils having conventional flap mechanisms.
TECHNION RESEARCH AND DEVELOPMEN T FOUNDATION LTD. (Israël)
Inventeur(s)
Cohen, Oren
Ilan Haham, Gil
Sidorenko, Pavel
Lahav, Oren
Peleg, Or
Chen, Bing Kuan
Abrégé
A ptychography system is presented for imaging an object located in an object plane. The ptychography system comprises an optical system, and a detection device. The optical system comprises a single shot ptychography arrangement configured and operable to create light response patterns from the object in the object plane on a pixel matrix of the detection device during the same exposure session of the detection device, wherein the optical system further comprises at least one light coding device configured and operable to apply at least one predetermined coding function to at least one of illuminating light and the light response of the object being collected, and said detection device is configured and operable with a predetermined duration of the exposure session during which the pixel matrix detects the collected light, such that image data indicative of the detected light during a single exposure session is in the form of a coded light response of the object being illuminated.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (Israël)
THE UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (USA)
Inventeur(s)
Segev, Mordechai
Harari, Gal
Christodoulides, Demetrios N.
Bandres Motola, Miguel Angel
Abrégé
A topological laser system is described. The laser system comprises an array of optical elements arranged in an array and coupled between them such that the array is configured for supporting one or more topological modes. The plurality of optical elements comprises optical elements carrying gain material configured for emitting optical radiation in response to pumping energy. The laser system further comprises a pumping unit configured to provide pumping of a group of the optical elements of the array within at least a portion of the spatial region corresponding with said topological mode; and at least one output port optically coupled to one or more of the optical elements associated with said topological mode. The at least one output ports is configured for extracting a portion of light intensity from said laser system.
H01S 5/40 - Agencement de plusieurs lasers à semi-conducteurs, non prévu dans les groupes
G02B 6/122 - Éléments optiques de base, p. ex. voies de guidage de la lumière
H01S 5/04 - Procédés ou appareils pour l'excitation, p. ex. pompage
H01S 5/10 - Structure ou forme du résonateur optique
H01S 5/11 - Structure ou forme du résonateur optique comprenant une structure de bande photonique interdite
H01S 5/343 - Structure ou forme de la région activeMatériaux pour la région active comprenant des structures à puits quantiques ou à superréseaux, p. ex. lasers à puits quantique unique [SQW], lasers à plusieurs puits quantiques [MQW] ou lasers à hétérostructure de confinement séparée ayant un indice progressif [GRINSCH] dans des composés AIIIBV, p. ex. laser AlGaAs
H01S 5/02251 - Découplage de lumière utilisant des fibres optiques
TECHNION RESEARCH AND DEVELOPEMENT FOUNDATION LTD (Israël)
Inventeur(s)
Nemirovsky, Yael
Abrégé
A gas sensing device, comprising a bulk and an array of gas sensing elements that are thermally isolated from the bulk, wherein each gas sensing element of a plurality of gas sensing elements of the array comprises (i) a gas reactive element that has a gas dependent temperature parameter; (ii) a semiconductor temperature sensing element that is thermally coupled to the gas reactive element and is configured to generate detection signals that are responsive to a temperature of the gas reactive element; and (iii) multiple heating elements that are configured to heat the gas reactive element to at least one predefined temperature.
G01N 27/16 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps chauffé électriquement dépendant de variations de température produite par l'oxydation par combustion ou catalyse d'un matériau de l'espace environnant à tester, p. ex. d'un gaz
G01N 25/20 - Recherche ou analyse des matériaux par l'utilisation de moyens thermiques en recherchant la production de quantités de chaleur, c.-à-d. la calorimétrie, p. ex. en mesurant la chaleur spécifique, en mesurant la conductivité thermique
G01N 25/30 - Utilisation des éléments électriques réagissant à la chaleur
G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
G01K 7/01 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments semi-conducteurs à jonctions PN
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Shaked, Yuval
Timaner, Michael
Abrégé
The invention relates to an activating composition comprising a cell, which may be any cell type used for cell therapy, wherein the cell is activated by a chemotherapy agent. Further, there is provided an activating composition comprising a supernatant of a composition comprising a cell, which may be any cell type used for cell therapy, wherein the cell is activated by a chemotherapy agent and wherein the supernatant is used as a therapy. The invention further provides methods for treating or preventing a disease or a condition comprising the use of the activated composition.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Shaked, Yuval
Timaner, Michael
Abrégé
The invention relates to an activating composition comprising a cell, which may be any cell type used for cell therapy, wherein the cell is activated by a chemotherapy agent. Further, there is provided an activating composition comprising a supernatant of a composition comprising a cell, which may be any cell type used for cell therapy, wherein the cell is activated by a chemotherapy agent and wherein the supernatant is used as a therapy. The invention further provides methods for treating or preventing a disease or a condition comprising the use of the activated composition.
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Suss, Matthew
Guyes, Eric
Chen, Yinke
Uwayid, Rana
Abrégé
inter alia inter alia, passing an ionic solution comprising ions having distinct hydrated sizes, through an electrode capacitor assembly comprising at least one carbon-based electrode which is modified with negatively or positively charged surface groups. Further provided is a method for selective separation of ionic species from an ionic solution comprising passing the ionic solution comprising a first positively charged ion and a second positively charged in through an electrode capacitor assembly, wherein the first modified electrode comprises carbon modified with sulfonate surface groups.
C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
H01G 11/30 - Électrodes caractérisées par leur matériau
C02F 103/08 - Eau de mer, p. ex. pour le dessalement
99.
MULTI-FUNCTIONAL FIELD EFFECT TRANSISTOR WITH INTRINSIC SELF-HEALING PROPERTIES
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED (Israël)
Inventeur(s)
Haick, Hossam
Khatib, Muhammad
Abrégé
The present invention provides a self-healing field-effect transistor (FET) device comprising a self-healing substrate and a self-healing dielectric layer, said substrate and said layer comprising a disulfide-containing poly(urea-urethane) (PUU) polymer, wherein the dielectric layer has a thickness of less than about 10 µm, a gate electrode, at least one source electrode, and at least one drain electrode, said electrodes comprising electrically conductive elongated nanostructures; and at least one channel comprising semi-conducting elongated nanostructures. Further provided is a method for fabricating the FET device.
G01N 27/12 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de l'absorption d'un fluideRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un corps solide dépendant de la réaction avec un fluide
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
100.
Electrokinetically separating, encapsulating and extracting analytes on a microfluidic device
Technion Research and Development Foundation Ltd. (Israël)
Inventeur(s)
Kaigala, Govind
Paratore, Federico
Gökçe, Onur
Bercovici, Moran
Kooten, Xander Van
Abrégé
Embodiments of the invention are directed to a method of separating and encapsulating an analyte on a microfluidic device in order to extract the analyte. A microfluidic device is provided having a main microchannel and a set of one or more auxiliary microchannels, each branching to the main microchannel at respective junctions therewith. A mixture is introduced as a single phase in the main microchannel in order to electrokinetically separate an analyte from the introduced mixture, and in order to confine the separated analyte in a microchannel portion of the main microchannel. The microchannel portion adjoins one of the junctions. One or more encapsulating volumes of an encapsulating phase are injected in the main microchannel via one or more of the auxiliary microchannels. The encapsulating phase is immiscible with said single phase. The encapsulated analyte is extracted from the main microchannel via one or more of the auxiliary microchannels.