Abrégé

A method for measuring a parameter of a substrate, comprises receiving pump radiation. A metrology target on the substrate is irradiated with the received radiation, thereby generating, through resonances, harmonic generated radiation. Using a metrology sensor, intensities are detected of at least two opposite radiation orders of the harmonic generated radiation diffracted by the metrology target. The parameter of the substrate is determined based on the intensities of the at least two opposite radiation orders and a peak wavelength of the harmonic generated radiation.

Classes IPC  ?

• G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
• G01B 11/02 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur

Abrégé

A method and a system for operating a quantum logic gate in an array of trapped ion qubits are described, wherein the method may comprise trapping an array of ion qubits using an electro-magnetic trap; determining an optical signal function to be applied to a first ion qubit and a second ion qubit in the qubit array based on gate operation conditions; generating a polarized optical signal, preferably a linearly polarized pulse, based on the optical signal function; and, applying the polarized optical signal to the first ion qubit and second ion qubit using a first optical tweezer focused onto the first ion qubit and a second optical tweezer focused onto the second ion qubit.

Classes IPC  ?

• G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit

Abrégé

Fusarium oxysporumFusarium oxysporum.Fusarium oxysporum.

Classes IPC  ?

• A01H 1/04 - Procédés de sélection
• A01H 5/08 - Fruits
• A01H 6/82 - Solanaceae, p. ex. poivron, tabac, pomme de terre, tomate ou aubergine
• C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
• C12N 9/22 - Ribonucléases
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

Disclosed is a Fourier-transform spectrometer comprising a beamsplitting arrangement operable to define a first radiation source and a second radiation source from a common radiation source, and at least one detector operable to detect interferogram data as a function of detection position in at least a first detection plane direction of a detection plane, the interferogram data resulting from interference of a first diverging beam emitted from said first radiation source and a second diverging beam emitted from said second radiation source. A processor is operable to: perform a linearization correction to said interferogram data to obtain linearized interferogram data; and Fourier transform the linearized interferogram data to obtain spectral characteristic data relating to the common radiation source.

Classes IPC  ?

• G01J 3/02 - SpectrométrieSpectrophotométrieMonochromateursMesure de la couleur Parties constitutives
• G01J 3/453 - Spectrométrie par interférence par corrélation des amplitudes
• G01J 3/36 - Étude de plusieurs bandes d’un spectre à l’aide de détecteurs distincts

Abrégé

A metrology system (100, 300, 400) for analyzing fuel at a target location in an EUV radiation source is disclosed. The metrology system comprises at least one radiation-emitting device (105, 110, 115, 305, 310, 315, 405, 410, 415) configured to emit radiation that is directed towards the target location (120, 320, 420). The metrology system also comprises at least one radiation-sensitive device (150, 350, 450) configured to sense radiation from the at least one radiation-emitting device that has passed through fuel at the target location. The at least one radiation-emitting device is configured to emit radiation of at least two different wavelengths. A radiation source (SO) for an EUV lithography apparatus, and a method of analyzing a fuel at a target location in such an EUV radiation source are also disclosed.

Classes IPC  ?

• H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma

Abrégé

A spectroscopic method and system for simultaneously analyzing molecular structure and size, of a single compound or of a mixture (M) of different molecules (M1, M2). A liquid volume (V) is provided with the mixture (M) having an initial concentration difference (ΔM) between different sub-volumes (Vm,Vs) which are fluidly interconnected and arranged at different locations along a spatial coordinate (X). A time- dependent spectrum (α[t,vj) is measured of light (L) interacting with part of the liquid volume (V), while the concentration difference (ΔM) at least partially equilibrates by diffusion of the different molecules (M1, M2) between the different sub-volumes (Vm,Vs) along the spatial coordinate (X). The time-dependent spectrum (α[t,vj) comprises respective distinct spectral signatures (α1,α2) of the respective different molecules (M1, M2). Each spectral signature (α1,α2) can have a distinct time- dependent evolution (τ1,τ2) in the time-dependent spectrum (α[t,vj) resulting from respective distinct diffusion characteristics (D1,D2) of the different molecules (M1, M2).

Classes IPC  ?

• G01N 21/3577 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge pour l'analyse de liquides, p. ex. l'eau polluée
• G01N 21/05 - Cuvettes à circulation de fluides

Abrégé

A method for determining a vertical position of a structure on a substrate with respect to a nominal vertical position is disclosed. The method comprises obtaining complex field data relating to scattered radiation from said structure, for a plurality of different wavelengths, determining variation in a phase parameter with wavelength from said complex field data; and determining said vertical position with respect to a nominal vertical position from the determined variation in phase with wavelength.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G01N 21/21 - Propriétés affectant la polarisation
• G03H 1/04 - Procédés ou appareils pour produire des hologrammes

Abrégé

Disclosed is an illumination arrangement for providing at least one radiation beam for use as an illumination beam and/or reference beam in a metrology device. The illumination arrangement comprises at least one radiation beam modifier module operable to receive source illumination and output a modified radiation beam comprising a first beam component and a second beam component. Each radiation beam modifier module comprises at least one path length varying arrangement for controllably varying the optical path length of at least one of said first beam component and said second beam component, such that said first beam component and second beam component of said modified radiation beam comprise a respective different optical path length.

Classes IPC  ?

• G03F 9/00 - Mise en registre ou positionnement d'originaux, de masques, de trames, de feuilles photographiques, de surfaces texturées, p. ex. automatique
• G02B 5/18 - Grilles de diffraction
• G02B 27/00 - Systèmes ou appareils optiques non prévus dans aucun des groupes ,
• G03H 1/04 - Procédés ou appareils pour produire des hologrammes
• G03F 7/20 - ExpositionAppareillages à cet effet
• G01J 9/00 - Mesure du déphasage des rayons lumineuxRecherche du degré de cohérenceMesure de la longueur d'onde des rayons lumineux
• G01N 15/14 - Techniques de recherche optique, p. ex. cytométrie en flux
• G02B 21/10 - Condensateurs donnant un éclairage sur fond noir
• G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
• G02B 26/06 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la phase de la lumière
• G02B 27/42 - Optique de diffraction

Abrégé

In accordance with the present invention there is provided a nanoparticle, comprising—a core, —an outer layer, and —a buffer layer located between said core and said outer layer, wherein the buffer layer prevents energy transfer between the core and the outer layer. In another aspect of the invention there is provided a nanoparticle as described herein for use in therapy, a nanoparticle according as described herein for use in treatment of a tumor, and a nanoparticle as used herein for use in in vivo imaging According to another aspect of the invention there is provided a method for the production of a nanoparticle as described herein, comprising the steps of—heating of a solution comprising core precursors, followed by—injection of a dispersion comprising buffer layer precursors, followed by—injection of a dispersion comprising outer layer precursors. Another aspect of the invention is a method for in vivo imaging or treatment or both of a human or animal, comprising the steps of: —administering nanoparticles as described herein to a patient, —irradiating at least part of the patient's body with one or more types of radiation. According to yet another aspect of the invention there is provided the use of a nanoparticle as described herein for therapy, in vivo imaging, or both.

Classes IPC  ?

• C01F 17/36 - Composés contenant des métaux de terres rares et au moins un élément autre qu’un métal des terres rares, l'oxygène ou l'hydrogène, p. ex. La4S3Br6 le seul anion étant un halogénure, p. ex. NaYF4
• B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p. ex. génie protéique ou administration de médicaments
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
• B82Y 40/00 - Fabrication ou traitement des nanostructures

Abrégé

The present invention relates to a method for vegetable sidestream valorisation. The method comprises (a) mixing vegetables with a composition comprising Lactobacilli reuteri bacteria; and (b) fermenting the mixture, whereby a vegetable paste is obtained. Fermentation is for 24-44 hours only and there is no need to add water, heat or nutrients.

Classes IPC  ?

• A23L 19/20 - Produits à base de fruits ou de légumesLeur préparation ou leur traitement par macération ou fermentation, p. ex. choucroute ou conserves au vinaigre
• A23L 29/00 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement
• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques

Abrégé

Methods and systems are disclosed for determining a power budget for processor cores of a multi-core processor. The method comprises determining or receiving a threshold temperature for each processor core of the plurality of processor cores, and determining or receiving a current temperature for each processor core of the plurality of processor cores. The method further comprises analytically computing, for one or more processor cores of the plurality of processor cores, one or more respective amounts of power that result in the one or more processor cores attaining their respective threshold temperature at the end of a current epoch, based on the current temperatures and on a thermal model of the processor. The thermal model may comprise a mathematical representation of heat generation and heat flow in the processor. The method further comprises determining a power budget for the one or more processor cores based on the computed one or more respective amounts of power. In an embodiment, the method may further comprise determining or receiving the thermal model.

Classes IPC  ?

• G06F 1/20 - Moyens de refroidissement
• G06F 1/3206 - Surveillance d’événements, de dispositifs ou de paramètres initiant un changement de mode d’alimentation
• G06F 1/324 - Économie d’énergie caractérisée par l'action entreprise par réduction de la fréquence d’horloge
• G06F 1/3296 - Économie d’énergie caractérisée par l'action entreprise par diminution de la tension d’alimentation ou de la tension de fonctionnement

Abrégé

Disclosed is a method for measuring a target located on a substrate beneath at least one layer. The method comprises exciting said at least one layer with pump radiation comprising at least one pump wavelength, so as to generate an acoustic wave within said at least one layer which reflects of said target thereby generating an acoustic replica of said target at a surface of said substrate and illuminating said acoustic replica with probe radiation comprising at least one probe wavelength and capturing the resultant scattered probe radiation, scattered from the acoustic replica. One or both of said exciting step and said illuminating step comprises generating Surface Plasmon Polaritons (SPPs) on residual topography of said at least one layer resultant from said target.

Classes IPC  ?

• G03F 9/00 - Mise en registre ou positionnement d'originaux, de masques, de trames, de feuilles photographiques, de surfaces texturées, p. ex. automatique

Abrégé

BacillusBacillusBacillus host cell of the invention under conditions conducive for the production of the polypeptide or compound of interest.

Classes IPC  ?

• C07K 14/32 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Bacillus (G)
• C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
• C12P 7/02 - Préparation de composés organiques contenant de l'oxygène contenant un groupe hydroxyle
• C12P 13/02 - Amides, p. ex. chloramphénicol
• C12P 17/04 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'oxygène comme unique hétéro-atome du cycle contenant un hétérocycle à cinq chaînons, p. ex. griséofulvine
• C12P 17/06 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'oxygène comme unique hétéro-atome du cycle contenant un hétérocycle à six chaînons, p. ex. fluorescéine
• C12P 17/12 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'azote comme unique hétéro-atome du cycle contenant un hétérocycle à six chaînons
• C12P 23/00 - Préparation de composés contenant un cycle cyclohexène comportant une chaîne latérale non saturée d'au moins dix atomes de carbone liés par des doubles liaisons conjuguées, p. ex. carotènes
• C12P 25/00 - Préparation de composés contenant des noyaux alloxazine ou iso-alloxazine, p. ex. riboflavine

Abrégé

The present invention relates to variants of a monomeric Scarlet Red Fluorescent protein (mScarlet RFP) having enhanced intrinsic brightness and maturation. Said variants comprise at least amino acid substitutions V196I and/or G220A, and optionally amino acid substitution T74I, when compared to the amino acid sequence of synthetically designed mScarlet RFP. The V196I and/or G220A variants of the present invention may comprise one or more further amino acid substitutions. Preferred additional amino substitutions are E219V or the combination of T107S and G156V. The combination of E219V, T107S and G156V in addition to V196I and/or G220A, and optionally T74I, was found to have a beneficial effect on the intrinsic brightness and maturation of the variants of the invention. In particular, the addition of Y84W, Y194F in addition to E219V, T107S, G156V, V196I and/or G220A with optionally K48R, K183R or T74I, N99I, A105T, T128G, K140R was of even larger benefit for the intrinsic brightness and maturation of the variants of the invention.

Classes IPC  ?

• A61K 49/00 - Préparations pour examen in vivo
• C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés

Abrégé

A resist composition for use in the fabrication of integrated circuits, the use of a resist composition, and a lithographic method utilising a resist composition, wherein the resist composition comprises an alkyltin-oxo cage having a counterion selected from tetrakis(pentafluorophenyl) borate, tetrakis[3,5-bis(trifluoromethyl)phenyl]borate, tetrakis[3,5-bis(tert-butyl)phenyl]borate, and tetrakis[(3,5-bis(l,l,l,3,3,3-hexafluoro-2-methoxypropan-2-yl)phenyl)phenyl]borate. A lithographic method comprising the steps of: a) providing a resist composition comprising an alkyltin-oxo cage having a counterion selected from the above borate groups; b) exposing the resist composition to a patterned radiation beam or an electron beam to form a pattern in the resist composition; and c) developing the resist to form a circuit pattern.

Classes IPC  ?

• G03F 7/004 - Matériaux photosensibles

Abrégé

Disclosed is a metrology apparatus and method for measurement of a diffractive structure on a substrate. The metrology apparatus comprises a radiation source operable to provide first radiation for excitation of the diffractive structure such that high harmonic second radiation is generated from said diffractive structure and/or substrate; and a detection arrangement operable to detect said second radiation, at least a portion of which having been diffracted by said diffractive structure.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G01N 21/47 - Dispersion, c.-à-d. réflexion diffuse
• G01N 21/956 - Inspection de motifs sur la surface d'objets
• G01N 23/22 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux

Abrégé

Disclosed is a metrology apparatus for measurement of a target formed on a substrate by a lithographic process and associated method. The metrology apparatus comprises a radiation source operable to provide first radiation; a configured solid high harmonic generation medium being configured to receive and be excited by said first radiation to generate high harmonic second radiation from an output surface of the configured solid high harmonic generation medium; and a detection arrangement operable to detect said second radiation, at least a portion of which having been scattered by said target. The configured solid high harmonic generation medium is configured to shape the beam of said second radiation and/or separate said first and second radiation.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G02F 1/35 - Optique non linéaire
• H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma

Abrégé

The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.

Classes IPC  ?

• C07K 1/04 - Procédés généraux de préparation de peptides sur des supports
• C07K 1/107 - Procédés généraux de préparation de peptides par modification chimique de peptides précurseurs
• C07K 7/56 - Peptides cycliques contenant au moins une liaison peptidique anormale comportant au moins une liaison peptidique anormale dans le cycle cyclisés autrement que par l'acide diamino-2,4 butanoïque
• C07K 7/64 - Peptides cycliques ne comportant que des liaisons peptidiques normales
• C40B 30/04 - Procédés de criblage des bibliothèques en mesurant l'aptitude spécifique à se lier à une molécule cible, p. ex. liaison anticorps-antigène, liaison récepteur-ligand
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

The invention provides a stereo lithographic 3D printing assembly comprising a digital projection system for projecting a first pattern having a first resolution at a projection location, and a photo mask system for projecting a second pattern having a second resolution at said projection location. This provides a fast 3D printing assembly allowing high resolution details.

Classes IPC  ?

• B29C 64/286 - Filtres optiques, p. ex. masques
• B29C 64/129 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet

Abrégé

Disclosed is a wavefront sensor for measuring a wavefront of a radiation. The wavefront sensor comprises a mask comprising a pattern located in path of the radiation to interact with the radiation. The radiation impinging on the mask forms a radiation detection pattern on a radiation detector subsequent to the mask, and the pattern of the mask is designed at least partly based on a requirement of the radiation detection pattern.

Classes IPC  ?

• G01J 1/04 - Pièces optiques ou mécaniques
• G01J 1/42 - Photométrie, p. ex. posemètres photographiques en utilisant des détecteurs électriques de radiations
• G01J 9/00 - Mesure du déphasage des rayons lumineuxRecherche du degré de cohérenceMesure de la longueur d'onde des rayons lumineux
• G03F 7/20 - ExpositionAppareillages à cet effet

Abrégé

In accordance with the present invention there is provided a nanoparticle, comprising - a core, - an outer layer, and - a buffer layer located between said core and said outer layer, wherein the buffer layer prevents energy transfer between the core and the outer layer. In another aspect of the invention there is provided a nanoparticle as described herein for use in therapy, a nanoparticle according as described herein for use in treatment of a tumor, and a nanoparticle as used herein for use in in vivo imaging. According to another aspect of the invention there is provided a method for the production of a nanoparticle as described herein, comprising the steps of - heating of a solution comprising core precursors, followed by - injection of a dispersion comprising buffer layer precursors, followed by - injection of a dispersion comprising outer layer precursors. Another aspect of the invention is a method for in vivo imaging or treatment or both of a human or animal, comprising the steps of: - administering nanoparticles as described herein to a patient, - irradiating at least part of the patient's body with one or more types of radiation. According to yet another aspect of the invention there is provided the use of a nanoparticle as described herein for therapy, in vivo imaging, or both.

Classes IPC  ?

• C01F 17/30 - Composés contenant des métaux de terres rares et au moins un élément autre qu’un métal des terres rares, l'oxygène ou l'hydrogène, p. ex. La4S3Br6
• B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
• B82Y 40/00 - Fabrication ou traitement des nanostructures

Abrégé

An EUV radiation source comprising a fuel emitter configured to produce fuel droplets; a laser system configured to illuminate a fuel droplet at a plasma formation region, the laser system comprising: a first laser configured to produce radiation of a first wavelength in a first radiation beam, a second laser configured to produce radiation of a second wavelength in a second radiation beam, and a first parametric amplifier arranged to receive the radiation of the first wavelength and radiation of the second wavelength and generate an amplified radiation beam; and a beam delivery system for delivering the amplified radiation beam to the plasma formation region.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma
• G02F 1/39 - Optique non linéaire pour la génération ou l'amplification paramétrique de la lumière, des infrarouges ou des ultraviolets

Abrégé

In embodiments the invention relates to means and methods for the treatment of Parkinson's disease. In some embodiments the means and methods involve a PDE2 inhibitor, a PDE11 inhibitor or a combination thereof, optionally together with a GUCY2C agonist.

Classes IPC  ?

• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
• A61K 31/52 - Purines, p. ex. adénine
• A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
• A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
• A61K 31/404 - Indoles, p. ex. pindolol
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

Methods and apparatus for forming a patterned layer of material are disclosed. In one arrangement, a deposition-process material is provided in gaseous form. A layer of the deposition-process material is formed on the substrate by causing condensation or deposition of the gaseous deposition-process material. A selected portion of the layer of deposition-process material is irradiated to modify the deposition-process material in the selected portion.

Classes IPC  ?

• C23C 16/04 - Revêtement de parties déterminées de la surface, p. ex. au moyen de masques
• C23C 16/26 - Dépôt uniquement de carbone
• C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
• C23C 16/46 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour le chauffage du substrat
• C23C 16/48 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement par irradiation, p. ex. par photolyse, radiolyse ou rayonnement corpusculaire
• C23C 16/56 - Post-traitement
• C23C 14/04 - Revêtement de parties déterminées de la surface, p. ex. au moyen de masques
• H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
• G03F 7/004 - Matériaux photosensibles
• G03F 7/16 - Procédés de couchageAppareillages à cet effet
• G03F 7/36 - Dépouillement selon l'image non couvert par les groupes , p. ex. utilisant un courant gazeux, un plasma

Abrégé

A dark field digital holographic microscope is disclosed which is configured to determine a characteristic of interest of a structure. The dark field digital holographic microscope comprises an illumination device configured to provide at least: a first beam pair comprising a first illumination beam of radiation (1010) and a first reference beam of radiation (1030) and a second beam pair comprising a second illumination beam of radiation (1020) and a second reference beam of radiation (1040); and one or more optical elements (1070) operable to capture a first scattered radiation and to capture a second scattered radiation scattered by the structure resultant from the first and second illumination beams respectively. The beams of the first beam pair are mutually coherent and the beams of the second beam pair are mutually coherent. The illumination device is configured to impose incoherence (ADI) between the first beam pair and second beam pair.

Classes IPC  ?

• G03H 1/04 - Procédés ou appareils pour produire des hologrammes
• G03H 1/26 - Procédés ou appareils adaptés spécialement pour produire des hologrammes multiples ou pour en obtenir des images, p. ex. procédés pour l'holographie à plusieurs couleurs
• G03F 7/20 - ExpositionAppareillages à cet effet

Abrégé

The present invention relates to a liquid composition comprising living green microalgae for improving plant growth. The liquid composition is prepared by growing green microalgae at a pH of 10-12 in the presence of hydrogen carbonate as the inorganic carbon source. The liquid composition may be stored at 4 to 25 degrees C. until use. The liquid composition may be used to improve fertilizers.

Classes IPC  ?

• A01G 33/00 - Culture des algues
• C05G 5/23 - Solutions
• C05F 11/00 - Autres engrais organiques
• C05G 5/27 - Dispersions, p. ex. suspensions, émulsions
• C05G 3/00 - Mélanges d'un ou plusieurs engrais avec des additifs n'ayant pas une activité spécifique d'engrais

Abrégé

Disclosed is a method for a metrology measurement on an area of a substrate comprising at least a portion of a target structure. The method comprises receiving a radiation information representing a portion of radiation scattered by the are, and using a filter in a Fourier domain for removing or suppressing at least a portion of the received radiation information that does not relate to radiation that has been scattered by the target structure for obtaining a filtered radiation information for the metrology measurement, wherein characteristics of the filter are based on target information about the target structure.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G01N 21/956 - Inspection de motifs sur la surface d'objets

Abrégé

Disclosed is a method of determining a complex-valued field relating to a structure, comprising: obtaining image data relating to a series of images of the structure, for which at least one measurement parameter is varied over the series and obtaining a trained network operable to map a series of images to a corresponding complex-valued field. The method comprises inputting the image data into said trained network and non-iteratively determining the complex-valued field relating to the structure as the output of the trained network. A method of training the trained network is also disclosed.

Classes IPC  ?

• G03F 1/84 - Inspection
• G01N 21/956 - Inspection de motifs sur la surface d'objets
• G03F 7/20 - ExpositionAppareillages à cet effet
• G06T 7/00 - Analyse d'image
• G03H 1/04 - Procédés ou appareils pour produire des hologrammes

Abrégé

The invention provides a stereo lithographic 3D printing assembly comprising a digital projection system for projecting a digitally defined first pattern having a first resolution at a projection location, and a photo mask system for projecting a second pattern having a second resolution and said second pattern and said first pattern aligned with one another at said projection location, said photo mask system providing at least one photo mask between said digital projection system and said projection location. This provides a fast 3D printing assembly allowing high resolution details.

Classes IPC  ?

• G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
• B29C 64/129 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque
• B29C 64/286 - Filtres optiques, p. ex. masques
• G03F 7/20 - ExpositionAppareillages à cet effet

Abrégé

The invention provides a stereo lithographic 3D printing assembly comprising a digital projection system for projecting a digitally defined first pattern having a first resolution at a projection location, and a photo mask system for projecting a second pattern having a second resolution and said second pattern and said first pattern aligned with one another at said projection location, said photo mask system providing at least one photo mask between said digital projection system and said projection location. This provides a fast 3D printing assembly allowing high resolution details.

Classes IPC  ?

• G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
• G03F 7/20 - ExpositionAppareillages à cet effet
• B29C 64/129 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque
• B29C 64/286 - Filtres optiques, p. ex. masques
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet

Abrégé

The invention pertains to a process for preparing phosphoric acid from a solid phosphorus-containing material, comprising the steps of: - reacting a solid phosphorus-containing material with strong acid in an amount of 1.0-15 mole acid, calculated as protons, per mole of phosphorus (calculated as P) in the solid phosphorus-containing material in a monophasic reaction medium comprising an organic solvent, to form a solution of phosphoric acid in organic solvent and remaining solid material, - separating the solution of phosphoric acid in organic solvent from the remaining solid material. It has been found that phosphoric acid can be recovered from a solid phosphorus-containing material in high purity and efficiency via a solid-state rearrangement/elution process. The process according to the invention does not require the use of the large amounts of water required by the conventional dissolution/extraction processes known in the art. The solution of phosphoric acid in organic solvent can be used as a starting material for further processes.

Classes IPC  ?

• C01B 25/222 - Préparation par réaction de produits contenant un phosphate avec un acide, p. ex. procédé par voie humide avec l'acide sulfurique, avec un mélange d'acides consistant principalement en acide sulfurique ou un mélange de composés formant de l'acide sulfurique in situ, p. ex. avec un mélange d'anhydride sulfureux, d'eau et d'oxygène
• C01B 25/28 - Phosphates d'ammonium
• C01B 25/46 - Préparation comportant une extraction solvant-solvant
• C07D 251/56 - Préparation de la mélamine

Abrégé

Geobacillus stearothermophilus Geobacillus stearothermophilus wherein the variants comprise one or more amino acid substitutions compared to the amino acid sequence of the parent LysEDH. These amine dehydrogenase variants are suitable biocatalysts for reductive amination of carbonyl containing compounds of which the acyl group is attached to a group that cannot readily be replaced by another group.These amine dehydrogenase variants are also suitable biocatalysts for the oxidative deamination of racemic chiral amines.

Classes IPC  ?

• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci

Abrégé

The invention pertains to a process for manufacturing silicon or germanium quantum dots which process comprises the steps of reacting a Zintl salt or intermetallie compound of post-transition metals or metalloids of silicon or germanium with a halogen-containing oxidizing agent to form halide-terminated silicon or germanium quantum dots; subjecting the halide-terminated silicon or germanium quantum dots to a reduction step by reaction with a reducing agent, to form hydride-terminated silicon or germanium quantum dots; and subjecting the hydride-terminated silicon or germanium quantum dots to, respectively, a hydrosilylation reaction or hydrogermylation reaction with a passivating agent, to form passivated silicon or germanium quantum dots. The process according to the invention makes it possible to obtain quantum dots with a high quantum yield. The invention also pertains to silicon or germanium quantum dots with a quantum yield of at least 20% at an excitation wavelength of 350 nm, and/or at least 15% at 370 nm.

Classes IPC  ?

• C09K 11/66 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du germanium, de l'étain ou du plomb
• C09K 11/59 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du silicium
• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension

Abrégé

The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.

Classes IPC  ?

• C07K 1/107 - Procédés généraux de préparation de peptides par modification chimique de peptides précurseurs
• C07K 1/04 - Procédés généraux de préparation de peptides sur des supports
• C07K 7/56 - Peptides cycliques contenant au moins une liaison peptidique anormale comportant au moins une liaison peptidique anormale dans le cycle cyclisés autrement que par l'acide diamino-2,4 butanoïque
• C07K 7/64 - Peptides cycliques ne comportant que des liaisons peptidiques normales
• C40B 30/04 - Procédés de criblage des bibliothèques en mesurant l'aptitude spécifique à se lier à une molécule cible, p. ex. liaison anticorps-antigène, liaison récepteur-ligand
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

An EUV radiation source of a laser-produced-plasma type, comprising: a fuel emitter configured to produce fuel droplets; and a laser system configured to illuminate a fuel droplet with radiation for converting the fuel droplet into a plasma at a plasma formation region; wherein the laser system comprises: a laser configured to produce radiation of a first wavelength; and a nonlinear medium configured to receive radiation of the first wavelength, produce radiation of a second wavelength using a nonlinear optical process at a radiation conversion region, and deliver radiation of the second wavelength to the plasma formation region; wherein the second wavelength is longer than the first wavelength.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma

Abrégé

In embodiments the invention relates to means and methods for the treatment of Parkinson's disease. In some embodiments the means and methods involve a PDE2 inhibitor, a PDE11 inhibitor or a combination thereof, optionally together with a GUCY2C agonist.

Classes IPC  ?

• A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 31/52 - Purines, p. ex. adénine
• A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
• A61K 31/404 - Indoles, p. ex. pindolol
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61P 25/16 - Antiparkinsoniens
• A61K 38/00 - Préparations médicinales contenant des peptides
• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides

Abrégé

Disclosed is a method for obtaining a computationally determined interference electric field describing scattering of radiation by a pair of structures comprising a first structure and a second structure on a substrate. The method comprises determining a first electric field relating to first radiation scattered by the first structure; determining a second electric field relating to second radiation scattered by the second structure; and computationally determining the interference of the first electric field and second electric field, to obtain a computationally determined interference electric field.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet

Abrégé

The invention pertains to a process for manufacturing aromatic nitriles, wherein a starting material selected from the group of aromatic primary alcohols and aromatic aldehydes is contacted under reaction conditions in a reaction vessel with an inorganic amine compound and molecular oxygen in the presence of a Cu-dependent alcohol oxidase. The process of the invention makes it possible to prepare aromatic nitriles from easily available starting materials, namely aromatic primary alcohols or aldehydes, in high efficiency, without having to rely on cyanidesor azides, or stringent reaction conditions.

Classes IPC  ?

• C12P 13/00 - Préparation de composés organiques contenant de l'azote
• C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)

Abrégé

Device (1) for multi-dimensional liquid analysis, such as chromatography. The device comprises a first analysis channel (3) and one or more second analysis channels (5). The first analysis channel comprises a channel wall (21) with outlets (11) connecting the first analysis channel to one of the plurality of second analysis channels, and a valve (7) for opening or closing at least one of the one or more outlets (11)·

Classes IPC  ?

• G01N 30/46 - Modèles d'écoulement utilisant plus d'une colonne
• G01N 30/20 - Injection utilisant une valve d'échantillonnage
• G01N 30/60 - Préparation de la colonne
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p. ex. dispositifs d'aspiration, dispositifs d'injection

Abrégé

In embodiments the invention relates to means and methods for the treatment of Parkinson's disease. In some embodiments the means and methods involve a GUCY2C agonist. The invention also relates to test systems and cells that are suited to identify new candidate compounds for the treatment of Parkinson's disease.

Classes IPC  ?

• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
• A61P 25/16 - Antiparkinsoniens
• A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
• C12N 9/88 - Lyases (4.)
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

The invention provides an assembly comprising: a recording assembly for recording a time-based brain-related signal; a stimulus generator for providing a stimulus, and a computer assembly, functionally coupled to said recording assembly and to said stimulus generator, said computer assembly comprising: a memory for storing at least a data segment of said time-based brain-related signal during recording of said time-based brain-related signal, and a computer program which, when running on said computer assembly, functionally real-time performs: retrieving a most-recent data segment of said stored data segment of said time-based brain-related signal; fitting at least one curve to said retrieved most-recent data segment; predicting a future continuation of said most-recent data segment using said at least one curve fitted to said most-recent data segment; detecting a predefined pattern in said predicted future continuation for predicting occurrence of said predefined pattern, and defining a predicted event time of said predefined pattern, said predicted event time being in the future with respect to said most-recent data segment, and actuating said stimulus generator for providing a stimulus within a predefined event time window of said predicted event time.

Classes IPC  ?

• A61B 5/048 - Détection de la répartition de fréquence dans les signaux
• A61B 5/0484 - Electro-encéphalographie utilisant des réponses provoquées
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The present invention relates to a liquid composition comprising living green microalgae for improving plant growth. The liquid composition is prepared by growing green microalgae at a pH of 10-12 in the presence of hydrogen carbonate as the inorganic carbon source. The liquid composition may be stored at 4 to 25 degrees C until use. The liquid composition may be used to improve fertilizers.

Classes IPC  ?

• A01G 33/00 - Culture des algues
• C05F 11/00 - Autres engrais organiques
• C05G 3/00 - Mélanges d'un ou plusieurs engrais avec des additifs n'ayant pas une activité spécifique d'engrais

Abrégé

Method for manufacturing fluoro(hydro)carbon-substituted silicon or germanium quantum dots which comprises the steps of: - reacting a Zintl salt or intermetallic compound of post- transition metals or metalloids of silicon or germanium with a halogen-containing oxidizing agent to form halide-terminated silicon or germanium quantum dots, - reacting the halide-terminated silicon or germanium quantum dots with a fluoro(hydro)carbon agent selected from the group of metal-fluoro (hydro)carbon compounds of the formula MRq, wherein M is a metal selected from Group 1, 2, 4, 11, 12, 13, or 14 of the periodic table of elements, q is an integer which corresponds to the valence of the metal, and R is CFnHm- fluoro/hydro-carbon, wherein n is 1 or 2, m is 0 or 1, and the total of n and m is 2, wherein each R may be the same or different, metal-fluoro (hydro)carbon halide compounds of the formula NQaRp wherein N is a metal selected from Group 1, 2, 4, 11, 12, 13, or 14 of the periodic table of elements, Q is a halogen selected from F, Cl, Br, or I, wherein each Q may be the same or different, a and p are integers in the range of 1- 3, and the total of a and p corresponds to the valence of the metal, and R is as defined above, and metal-fluoro (hydro)carbon compounds of the formula CuR2Li, wherein R is as defined above, to form fluoro(hydro)carbon-substituted silicon or germanium quantum dots. The method makes it possible to obtain quantum dots with a tailored emission spectrum with high quality in a stable process. The particles obtained by this process are also claimed.

Classes IPC  ?

• C09K 11/66 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du germanium, de l'étain ou du plomb
• C09K 11/59 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du silicium
• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension

Abrégé

Methods and apparatus are disclosed for determining a characteristic of a structure. In one arrangement, the structure is illuminated with first illumination radiation to generate first scattered radiation. A first interference pattern is formed by interference between a portion of the first scattered radiation reaching a sensor and first reference radiation. The structure is also illuminated with second illumination radiation from a different direction. A second interference pattern is formed using second reference radiation. The first and second interference patterns are used to determine the characteristic of the structure. Azimuthal angles of the first and second reference radiations onto the sensor are different.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet

Abrégé

Disclosed is a method and associated apparatus for measuring a characteristic of interest relating to a structure on a substrate. The method comprises calculating a value for the characteristic of interest directly from the effect of the characteristic of interest on at least the phase of illuminating radiation when scattered by the structure, subsequent to illuminating said structure with said illuminating radiation.

Classes IPC  ?

• G02B 27/42 - Optique de diffraction
• G03F 7/20 - ExpositionAppareillages à cet effet
• G03H 1/04 - Procédés ou appareils pour produire des hologrammes
• G03H 1/00 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une imageLeurs détails spécifiques

Abrégé

A radiation source (SO) of a laser-produced plasma type is described. The radiation source (SO) comprises a droplet generator (3a) configured to provide a fuel droplet (60). The radiation source (SO) comprises a laser system (1) configured to provide a pre-pulse and a main-pulse. The pre-pulse is operative to condition the fuel droplet (60) for receipt of main pulse. The main pulse is operative to convert the conditioned fuel droplet (60) into plasma. The radiation source (SO) comprises a sensing system (16) configured for sensing a characteristic of an oscillation of a spatial mass distribution of the fuel droplet (60). The radiation source (SO) comprises a control system (44) operative to adjust a polarization of the pre-pulse under control of the sensed characteristic. The polarization of the pre- pulse may affect the spatial mass distribution of the conditioned fuel droplet (60).

Classes IPC  ?

• H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma

Abrégé

Methods and apparatus for forming a patterned layer of carbon are disclosed. In one arrangement, a selected portion of a surface of a solid structure is irradiated with extreme ultraviolet radiation in the presence of a carbon-containing precursor. The radiation interacts with the solid structure in the selected portion to cause formation of a layer of carbon in the selected portion from the carbon-containing precursor. The layer of carbon is formed in a pattern defined by the selected portion.

Classes IPC  ?

• C23C 16/04 - Revêtement de parties déterminées de la surface, p. ex. au moyen de masques
• C23C 16/26 - Dépôt uniquement de carbone
• C23C 16/48 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement par irradiation, p. ex. par photolyse, radiolyse ou rayonnement corpusculaire
• C23C 16/56 - Post-traitement

Abrégé

Multi-chromatic photoluminescent, oxide-capped semiconductor nanocrystals and methods for forming such semiconductor nanocrystals. The method includes exposing one or more oxide-capped semiconductors, preferably type IV semiconductor nanocrystals, to electron beam radiation, wherein the radiation has an energy between 1 and 30 keV, the radiation introducing color centers in the oxide that exhibit photoluminescence in at least the green band of the visible spectrum.

Classes IPC  ?

• C09K 11/59 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du silicium
• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension
• B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
• B82Y 40/00 - Fabrication ou traitement des nanostructures

Abrégé

Described is a metrology system for determining a characteristic of interest relating to at least one structure on a substrate, and associated method. The metrology system comprises a processor being configured to computationally determine phase and amplitude information from a detected characteristic of scattered radiation having been reflected or scattered by the at least one structure as a result of illumination of said at least one structure with illumination radiation in a measurement acquisition, and use the determined phase and amplitude to determine the characteristic of interest.

Classes IPC  ?

• G01B 11/24 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer des contours ou des courbes
• G03F 7/20 - ExpositionAppareillages à cet effet

Produits et services

Computer software (recorded programmes) in the field of scientific, human and industrial analysis and research; Downloadable electronic publications in the field of scientific, human and industrial analysis and research; Scientific, nautical, surveying, photographic, cinematographic, weighing, measuring, signalling, checking (supervision), life-saving and teaching apparatus and instruments; Apparatus and instruments for conducting, switching, transforming, accumulating, regulating or controlling electricity; Apparatus for recording, transmission or reproduction of sound or images; Recording substrates [magnetic]; Phonograph records; CD discs; DVDs/ high density optical discs; USB flash drives; Calculators; Data processing equipment; Computers; Decorative magnets; Luminous signs. Printed matter, printed documents and publications relating to the field of education, teaching, training and instruction, books, newspapers, handbooks (manuals), periodicals, magazines, prospectuses, printed forms; Stationery instructional and teaching material (excluding apparatus), Tickets, Seals [stamps], Forms, printed, Posters, albums, Yearbooks and calendars, Geographical maps, Signboards of paper or cardboard, Envelopes [stationery], Paper sheets [stationery]; Pencils, fountain pens, Nibs, Pen rests, Pencil lead holders, Lithographs, photographs, Blueprints, Paper weights and post cards, Bags (envelopes, pouches) of paper or plastic, for packaging. Training, education, teaching, Education, educational information, Vocational guidance [education or training advice]; Cross-border cooperation in the fields of teaching and training; Organisation of competitions for teaching purposes, Educational examination; Academies (education), Correspondence courses, distance learning; Arranging and conducting of training workshops, colloquiums, conferences, congresses, exhibitions, seminars, symposiums and concerts, organisation of exhibitions for cultural or educational purposes, organisation of sports competitions; Publication of activity reports, books, magazines, CD-ROMs, publication of texts, other than publicity texts, online publication of electronic books and journals, lending of books; Practical training [demonstration]; Providing of sports, scientific and cultural facilities; Entertainment, providing recreation facilities, Entertainment information, Recreation information, Ticket agents services (entertainment), Production of shows, Holiday camp services (entertainment), Club services (entertainment or education), Planning (Party -) [entertainment], Sport camp services, Museum facilities (Providing -) [presentation, exhibitions], Videotape and DVD editing/ high density optical discs, Production of television and radio programs; Layout design, other than for advertising purposes, Film production services, Videotaping/ Digital versatile discs ( DVD's)/ high density optical discs, Library services, Mobile library services; Discotheques; Cinema presentations, Rental of motion pictures, Rental of sound recordings; Photographic reporting. Human and industrial scientific analysis and research in the following disciplines: the arts, plastic arts, foreign languages, foreign literature and civilisations, humanities, music, cultural and artistic activities, performing arts, visual arts, language and linguistics, philosophy, law, communication and information science and technology, marketing techniques, management of companies and administrations, economic and social administration, public administration, economics, management, economic science, accounting, checks and audits, finance, journalism, management, political science, social science, physical and sports education, geography, history, archaeology, psychology, sociology, science and techniques in the field of physical and sporting activities, theology, human resource management, anthropology, ethnology, demography, urban planning and landscaping, vocational training and science, chemistry, biology, physics, civil and industrial engineering, computing, mathematics, life sciences, earth sciences, astronomy and environmental science, agronomy, engineering science, astrophysics, bioinformatics, biophysics, biochemistry, geophysics, medical science, odontological science, health, medicine, dental surgery, pharmacy, logopaedics, orthoptics, acupuncture, maieutics; Cross-border cooperation in the field of human and industrial scientific research; Engineering, engineering drawing, Material testing, Research and development for others; Engineering services, Research in the field of environmental protection; Architecture, Interior decoration consultation, Urban planning, Construction drafting; Quality control; Computer system design, conversion of data or of documents from a physical carrier to an electronic carrier, development (design) of software, computer programming, database recovery, providing of search engines for the Internet; Authenticating works of art.

Abrégé

A method for determining a characteristic of a feature in an object, the feature being disposed below a surface of the object is disclosed. The surface of the object is irradiated with a pulsed pump radiation beam so as to produce an acoustic wave in the object. The surface of the object is then irradiated with a measurement radiation beam. A portion of the measurement radiation beam scattered from the surface is received and a characteristic of the feature in the object is determined from at least a portion of the measurement radiation beam scattered from the surface within a measurement time period. A temporal intensity distribution of the pulsed pump radiation beam is selected such that in the measurement time period a signal to background ratio is greater than a signal to background ratio achieved using a single pulse of the pulsed pump radiation beam. The signal to background ratio is a ratio of: (a) signals generated at the surface by reflections of acoustic waves from the feature to (b) background signals generated at the surface by reflections of acoustic waves which have not reflected from the feature.

Classes IPC  ?

• G03F 9/00 - Mise en registre ou positionnement d'originaux, de masques, de trames, de feuilles photographiques, de surfaces texturées, p. ex. automatique

Abrégé

A metrology apparatus (302) includes a higher harmonic generation (HHG) radiation source for generating (310) EUV radiation. Operation of the HHG source is monitored using a wavefront sensor (420) which comprises an aperture array (424, 702) and an image sensor (426). A grating (706) disperses the radiation passing through each aperture so that the image detector captures positions and intensities of higher diffraction orders for different spectral components and different locations across the beam. In this way, the wavefront sensor can be arranged to measure a wavefront tilt for multiple harmonics at each location in said array. In one embodiment, the apertures are divided into two subsets (A) and (B), the gratings (706) of each subset having a different direction of dispersion. The spectrally resolved wavefront information (430) is used in feedback control (432) to stabilize operation of the HGG source, and/or to improve accuracy of metrology results.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G01J 9/00 - Mesure du déphasage des rayons lumineuxRecherche du degré de cohérenceMesure de la longueur d'onde des rayons lumineux

Abrégé

The invention provides an optical music recognition (OMR) assembly for converting sheet music, representing a music part as a first temporal representation, into a machine-processable representation of said piece of music that represents at least a pitch and duration of notes that are graphically represented in said sheet music and form said music part as a second temporal representation, said assembly comprising a data processor system and software which, when running on said data processor system: - retrieves a machine-processable representation of said sheet music; - generate a series of time slices of said sheet music, by applying a sliding window on said over said machine-processable representation of at least part of said sheet music; - defines a sequence-to-sequence system, said sequence-to-sequence system comprising: provide a convolutional neural network (CNN) for converting said time slices into a sequence of third representations of said sheet music, said CNN comprising an input layer and an output layer; provide a first, encoder recurrent neural network (RNN) as an encoder on said sequence of third representations, for providing a hidden representation of said sheet music, said first RNN having an input layer that is functionally coupled to said output layer of said CNN, and an output layer; * provide a second, decoder recurrent neural network (RNN) as a decoder to said hidden representation, for converting said hidden representation into said machine- processable representation, said second RNN having an input layer that is functionally coupled to said output layer of said first RNN, and an output for providing said machine-processable representation.

Classes IPC  ?

• G10H 1/00 - Éléments d'instruments de musique électrophoniques
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion
• G06N 3/02 - Réseaux neuronaux
• G10G 1/04 - TranspositionTranscription

Abrégé

The invention provides a device for detecting post-traumatic stress disorder (PTSD) in a subject, comprising a data processing assembly and a computer program product which, when running on said data processing assembly: - retrieves a first dataset representative of an electromagnetic brain-related signal from a frontal brain region of said subject during a non-rapid eye movement (NREM) stage sleep; - retrieves a second dataset representative of an electromagnetic brain-related signal from an occipital brain region of said subject during a rapid eye movement (REM) stage sleep; - calculates a first frequency spectrum from said first dataset and a second frequency spectrum from said second dataset; - evaluates a neuromarker from said first frequency spectrum and said second frequency spectrum, said neuromarker providing an indication for a presence of said PTSD in said subject.

Classes IPC  ?

• A61B 5/04 - Mesure de signaux bioélectriques du corps ou de parties de celui-ci
• A61B 5/048 - Détection de la répartition de fréquence dans les signaux
• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

In embodiments the invention relates to means and methods for the treatment of Parkinson's disease. In some embodiments the means and methods involve a GUCY2C agonist. The invention also relates to test systems and cells that are suited to identify new candidate compounds for the treatment of Parkinson's disease.

Classes IPC  ?

• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Abrégé

The invention provides an assembly comprising: - a recording assembly for recording a time-based brain-related signal; - a stimulus generator for providing a stimulus, and - a computer assembly, functionally coupled to said recording assembly and to said stimulus generator, said computer assembly comprising: - a memory for storing at least a data segment of said time-based brain-related signal during recording of said time-based brain-related signal, and - a computer program which, when running on said computer assembly, functionally real-time performs: - retrieving a most-recent data segment of said stored data segment of said time-based brain-related signal; - fitting at least one curve to said retrieved most-recent data segment; - predicting a future continuation of said most-recent data segment using said at least one curve fitted to said most-recent data segment; - detecting a predefined pattern in said predicted future continuation for predicting occurrence of said predefined pattern, and defining a predicted event time of said predefined pattern, said predicted event time being in the future with respect to said most-recent data segment, and - actuating said stimulus generator for providing a stimulus within a predefined event time window of said predicted event time.

Classes IPC  ?

• A61B 5/0482 - Electro-encéphalographie utilisant une rétroaction biologique
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/04 - Mesure de signaux bioélectriques du corps ou de parties de celui-ci
• A61M 21/02 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose pour provoquer le sommeil ou la relaxation, p. ex. par stimulation directe des nerfs, par hypnose ou par analgésie

Abrégé

A method of forming a high-resolution image of a sample using a scanning microscope controlled by a processor is described wherein the method comprises the steps of receiving or generating control information for controlling a scanning microscope, the control information defining a plurality of different periodic patterns on the basis of one or more pattern parameters, preferably the one or more pattern parameters, including at least one of: a spatial frequency, a periodicity direction, an initial phase; using the control information to control the scanning microscope to expose the sample to multiple illumination patterns, each exposure to an illumination pattern causing one or more optical excitations in the sample, the light originating from said optical excitations forming an emission light signal; controlling an imaging system to capture multiple images, each image being associated with an emission light signal of one of the multiple exposures, and, using a structured light reconstruction algorithm for forming a high-resolution image on the basis of the one or more pattern parameters.

Classes IPC  ?

• G02B 21/00 - Microscopes
• G02B 21/36 - Microscopes aménagés pour la photographie ou la projection

Abrégé

A lithographic apparatus is a machine that applies a desired pattern onto a substrate, usually onto a target portion of the substrate. As increasing numbers of layers, using increasing numbers of specific materials, are deposited on substrates, it becomes increasingly difficult to detect alignment marks accurately, in part due to one or more of the materials used in one or more of the layers being wholly or partially opaque to the radiation used to detect alignment marks. In a first step, the substrate is illuminated with excitation radiation. In a second step, at least one effect associated with a reflected material effect scattered by a buried structure is measured in a suitable fashion. The effect may in an example comprise a physical displacement of the surface of the substrate. In a third step, at least one characteristic of the structure based on the measured effect is derived.

Classes IPC  ?

• G01B 11/24 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer des contours ou des courbes
• G03F 9/00 - Mise en registre ou positionnement d'originaux, de masques, de trames, de feuilles photographiques, de surfaces texturées, p. ex. automatique
• G01B 17/06 - Dispositions pour la mesure caractérisées par l'utilisation de vibrations infrasonores, sonores ou ultrasonores pour mesurer des contours ou des courbes

Abrégé

Method and system for scanning microscopy are described. The system comprises a first optical system configured to move one or more focused illumination light spots over or through an optical active sample, the one or more focused illumination light spots causing local optical excitations in the optical active sample, the local optical excitations generating emission light. The system further comprises a second optical system configured to form at least a first emission light beam comprising first optical information and second emission light beam comprising second optical information on the basis of the emission light associated with the local optical excitations. The scanning microscopy system also comprises a lens system configured to focus the first emission light beam onto an image plane of an imaging system for forming a first image and configured to focus the second emission light beam onto the image plane of the imaging system for forming a second image. The system also comprises a moveable scanning mirror that is configured to move the focused first and second emission light beam over the image area of the imaging system when the one or more focused illumination light spots are moved over or through the sample.

Classes IPC  ?

• G02B 21/00 - Microscopes

Abrégé

An EUV radiation source (42, 300) is used for example in a lithographic apparatus or inspection apparatus. For generating EUV radiation (302), laser radiation (304) in a second waveband is directed to a target of liquid tin fuel (69) to cause generation of a plasma. Grating radiation (328) is delivered to the target prior to and/or during delivery of the laser radiation (304), producing an electromagnetic field having a spatial distribution that includes multiple peaks and troughs across the target (406). This causes a corresponding spatial variation in a property of the target, such as the refractive index. If high enough in energy, or it may cause ablation or plasma formation in a grating pattern. By one or more mechanisms, such as surface plasmon polaritons, this periodic variation in the optical properties of the target enhances absorption of the laser energy to improve conversion efficiency of the radiation source apparatus.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• H05G 2/00 - Appareils ou procédés spécialement adaptés à la production de rayons X, n'utilisant pas de tubes à rayons X, p. ex. utilisant la génération d'un plasma

Abrégé

The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.

Classes IPC  ?

• C07K 1/04 - Procédés généraux de préparation de peptides sur des supports
• C07K 1/107 - Procédés généraux de préparation de peptides par modification chimique de peptides précurseurs
• C07K 7/56 - Peptides cycliques contenant au moins une liaison peptidique anormale comportant au moins une liaison peptidique anormale dans le cycle cyclisés autrement que par l'acide diamino-2,4 butanoïque
• C07K 7/64 - Peptides cycliques ne comportant que des liaisons peptidiques normales
• C40B 30/04 - Procédés de criblage des bibliothèques en mesurant l'aptitude spécifique à se lier à une molécule cible, p. ex. liaison anticorps-antigène, liaison récepteur-ligand
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.

Classes IPC  ?

• C07K 1/04 - Procédés généraux de préparation de peptides sur des supports
• C07K 1/107 - Procédés généraux de préparation de peptides par modification chimique de peptides précurseurs
• C07K 7/56 - Peptides cycliques contenant au moins une liaison peptidique anormale comportant au moins une liaison peptidique anormale dans le cycle cyclisés autrement que par l'acide diamino-2,4 butanoïque
• C07K 7/64 - Peptides cycliques ne comportant que des liaisons peptidiques normales
• C40B 30/04 - Procédés de criblage des bibliothèques en mesurant l'aptitude spécifique à se lier à une molécule cible, p. ex. liaison anticorps-antigène, liaison récepteur-ligand
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

The present invention relates to a chimeric gene for the extracellular production in plant cells, transformed with the chimeric gene, of a pathogen effector, the chimeric gene comprising: (a) a promoter sequence which functions in plant cells; and (b) a coding sequence, operably linked to the promoter, encoding a fusion protein consisting of a pathogen effector fused in translation frame to a signal peptide for targeting said pathogen effector to the plant secretory pathway

Classes IPC  ?

• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C12N 15/52 - Gènes codant pour des enzymes ou des proenzymes
• C07K 14/37 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de champignons

Abrégé

The invention is related to multi-chromatic photoluminescent, oxide-capped semiconductor nanocrystals and methods for forming such semiconductor nanocrystals. The method includes exposing one or more oxide-capped semiconductor, preferably type IV semiconductor, nanocrystals to electron beam radiation, wherein the radiation has an energy between 1 and 30 ke V, the radiation introducing color centers in the oxide that exhibit photoluminescence in at least the green band of the visible spectrum.

Classes IPC  ?

• C09K 11/59 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du silicium
• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension

Abrégé

In an inspection apparatus, a target on the surface is illuminated with illuminating radiation that comprises first and second illuminating components. The illuminating components form one or more periodic illuminating patterns on the surface. A plurality of scattered radiation patterns formed by the illuminating radiation after scattering by the target is captured at a detector for a number of values of a controllable characteristic of at least one of the illuminating components. The captured radiation is then used to reconstruct data describing the target.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G02B 21/16 - Microscopes adaptés pour éclairage ultraviolet
• G01N 21/47 - Dispersion, c.-à-d. réflexion diffuse

Abrégé

A method is described for for assembling semiconductor nanocrystals comprising: - providing a binary system comprising semiconductor nanocrystals with an effective particle diameter of at most 20 nm, a first solvent, and a second solvent, - the system having * a Ta, which is which is the temperature of the system at which aggregation starts to take place, * a Ts, which is the solvent separation temperature of the system, * an aggregation temperature range, which is the range between Ta and Ts with Ta being included and Ts not being included, * a homogeneous temperature range which is below Ta when Ta is lower than Ts and which is above Ta when Ta is higher than Ts, * a heterogeneous temperature range which is above Ts when Ta is lower than Ts and below Ts when Ta is higher than Ts, and, - bringing the temperature of the binary system from a value in the homogeneous temperature range to a value in the aggregation temperature range, thereby causing formation of an aggregate of said semiconductor nanocrystals.

Classes IPC  ?

• H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
• C09K 11/08 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes
• C30B 29/48 - Composés AII BVI

Abrégé

A multilayer reflector for use in EUV lithography, for example, comprises alternating layers of Mo and RbxSiy. The RbxSiy and Mo interface is thermodynamically stable, reducing intermingling of the layers and preventing reduction in reflectivity. The RbxSiy layer can be hydrogenated to form RbSiH3. For the case of Mo/RbSiH3 an interlayer of RbH between Mo and RbSiH3 layers can be used. An Mo/RbH multilayer mirror is also useful.

Classes IPC  ?

• G03F 7/20 - ExpositionAppareillages à cet effet
• G03F 1/24 - Masques en réflexionLeur préparation
• G02B 5/08 - Miroirs
• G21K 1/06 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p. ex. pour focaliser ou pour modérer utilisant la diffraction, la réfraction ou la réflexion, p. ex. monochromateurs

Abrégé

Some embodiments are directed to a system and a method for estimating gaze from a set of eye measurement points that are indicative of a gaze pattern of a user viewing a scene. Some other embodiments are directed to obtaining sets of eye measurement points from different users viewing the same scene. In another embodiment, the different sets of eye measurement points are mapped to a common coordinate system for reciprocal calibration In yet another embodiment, a scene transformation for mapping the common coordinate system to a coordinate system associated with the scene can be calculated by matching eye measurement points from the common coordinate system to interest points of the scene. The scene transformation is thereby calculated more accurately than individually calculated scene transformations, thereby providing a more accurate estimate of the gaze points.

Classes IPC  ?

• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
• G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques

Abrégé

The invention provides a method for recognition of information in digital image data, said method comprising a learning phase on a data set of example digital images having known information, and characteristics of categories are computed automatically from each example digital image and compared to its known category, said method comprises training a convolutional neural network comprising network parameters using said data set, in which via deep learning each layer of said convolutional neural network is represented by a linear decomposition of all filters as learned in each layer into basis functions.

Classes IPC  ?

• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06N 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
• G06K 9/46 - Extraction d'éléments ou de caractéristiques de l'image

Abrégé

The present invention relates to compositions comprising anti-cariogenic bacteria for use in the oral cavity, which are able to minimize dental caries risk induced by sugar consumption and maintain good oral health. The compositions according to the invention comprise hydrogen peroxide- producing oral bacteria and fermentable saccharides and are able to inhibit cariogenic, acid-producing bacteria even at pH values of 5.5 or less. The probiotic compositions according to the invention are suitable for oral application and are preferably used in the oral cavity.

Classes IPC  ?

• A23G 4/12 - Chewing-gum caractérisé par la composition contenant des micro-organismes ou des enzymesChewing-gum caractérisé par la composition contenant des agents paramédicaux ou diététiques, p. ex. des vitamines
• A61K 8/99 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de micro-organismes autres que des algues ou des champignons, p. ex. à base de protozoaires ou de bactéries
• A61Q 11/00 - Préparations pour le nettoyage des dents, de la bouche ou des prothèses dentaires, p. ex. dentifricesBains de bouche
• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
• A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon

Abrégé

The present invention relates to a photosensitizer comprising a porphyrin compound of the formula (I) wherein: Ar1, Ar2, Ar3 and Ar4, are each independently selected from aryl or heteroaryl, wherein each of said aryl or heteroaryl substituents may be optionally substituted, X1, X2, X3, and X4 are each independently selected from H or halogen, whereby at least one of X1, X2, X3, and X4 is halogen; X5 and X6 are each independently selected from H, hydrocarbyl or a halogen-containing group, or are linked together form an aromatic ring; X7 and X8 are each independently selected from H, hydrocarbyl or a halogen-containing group, or are linked together form an aromatic ring; and M is a metal, P or Si.

Classes IPC  ?

• C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles

Abrégé

The invention pertains to a method for reduction of the cyanide content of a metals-containing wastewater fraction by contacting a wastewater fraction comprising cyanide compounds and metal compounds, with a metals content of at least 100 ppm, with hydrogen peroxide and a solid catalyst comprising at least 50 wt. % of a copper salt with a solubility of less than 10 exp (- 5) mol/liter (in water at 20°C, 1 atm). It has been found that when a solid catalyst comprising at least 50 wt. % of a copper salt with a solubility of less than 10 exp (- 5) mol/liter (in water at 20°C, 1 atm) is used in combination with hydrogen peroxide in the reduction of the cyanide content of a cyanide compound-containing wastewater fraction having a metal compound content of at least 100 ppm, a method is obtained which shows an efficient removal of cyanide compounds from a difficult to treat fraction.

Classes IPC  ?

• C02F 1/72 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par oxydation
• C02F 101/18 - Cyanures
• C02F 101/20 - Métaux lourds ou leurs composés
• C02F 101/38 - Composés organiques contenant de l'azote
• C02F 103/16 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter provenant de procédés métallurgiques, c.-à-d. de la production, de la purification ou du traitement de métaux, p. ex. déchets de procédés électrolytiques

Abrégé

The present subject matter relates to a device for trapping and eluting a liquid chromatography eluate. The device comprises a thermal modulator configured such that it may be fitted with a trapping column located at least substantially within the thermal modulator, and a temperature control unit operationally coupled to the thermal modulator. The thermal modulator has a heating, a cooling and a thermal maintenance mode. In the heating mode the thermal modulator is configured to increase the temperature of the trapping column when fitted by at least 25°C at a rate of at least 1°C per second; in the cooling mode the thermal modulator is configured to decrease the temperature of the trapping column when fitted by at least 25°C at a rate of at least 1°C per second; and in thermal maintenance mode the thermal modulator is configured to maintain the temperature of the trapping column when fitted. The device may be used in a 2D-LC system. The device may be used in a method of on-line solvent switching for an effluent from a liquid chromatography column. The device may focus analytes.

Classes IPC  ?

• G01N 30/40 - Modèles d'écoulement inversant le sens de circulation
• G01N 30/46 - Modèles d'écoulement utilisant plus d'une colonne
• G01N 30/30 - Contrôle des paramètres physiques du fluide vecteur de la température

Abrégé

The invention enables estimating gaze from a set of eye measurement points which are indicative of a gaze pattern of a user viewing a scene. Herein, use is made of the insight that gaze patterns of different users are similar for a same scene (010). The invention involves obtaining different sets of eye measurement points from different users viewing the same scene. The different sets of eye measurement points may be mapped to a common coordinate system, and there by mutually calibrated, based on the assumption that geometrically similar topologies between the different sets of eye measurement points are to be mapped to similar coordinates in the common coordinate system as they represent a similar or same gaze pattern.A scene transformation for mapping the common coordinate system to a coordinate system associated with the scene can be calculated by matching eye measurement points from the common coordinate system to interest points(012) of the scene. The scene transformation is thereby calculated more accurately than individually calculated scene transformations, thereby providing a more accurate estimate of the gaze points.

Classes IPC  ?

• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur

Abrégé

The invention relates to a novel catalytic composition comprising at least one nickel precursor A with at least one diphosphinamine ligand B1 of formula (R1 )(R'1 )P-N(R3)-P(R2)(R'2) or an iminobisphosphine ligand B2 of formula (R3)N=P(R1 )(R'1 )-P(R2)(R'2) or an iminobisphosphine ligand B'2 of formula (R3)N=P(R2)(R'2)-P(R1 )(R'1 ). The invention also relates to the use of said catalytic composition in a method for the oligomerisation of olefins.

Classes IPC  ?

• B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
• B01J 31/18 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination contenant de l'azote, du phosphore, de l'arsenic ou de l'antimoine

Abrégé

The invention relates to a novel disymmetric nickel-based complex and to the method for the production thereof from at least one diphosphinamine ligand B1 of formula (R1)(R'1)P-N(R3)-P(R2)(R'2), or an iminobisphosphine ligand B2 of formula (R3)N=P(R1)(R'1)-P(R2)(R'2). The invention also relates to the use of said complex in a method for the oligomerisation of olefins.

Classes IPC  ?

• C07F 15/04 - Composés du nickel
• C08F 4/80 - MétauxHydrures métalliquesComposés organiques de métalLeur utilisation comme précurseurs de catalyseurs choisis parmi les métaux non prévus dans le groupe choisis parmi les métaux du groupe du fer ou les métaux du groupe du platine
• C08F 10/02 - Éthylène
• C08F 10/06 - Propène

Abrégé

The invention pertains to a process for separating a mixture of alkanes which comprises straight-chain alkanes and branched alkanes, wherein the mixture is contacted with a molecular sieve under adsorption conditions resulting in adsorption of at least part of the alkane mixture onto the molecular sieve to form an adsorbed fraction, and subsequently subjecting the molecular sieve to desorption conditions thereby desorbing at least part of the adsorbed fraction from the molecular sieve, wherein the molecular sieve is a molecular sieve of ZIF-77 topology and pore size. It has been found that the use of a molecular sieve with ZIF-77 topology and pore size results in a process with a very high selectivity. More in particular, it has been found that a material with this structure shows a high adsorption selectivity, defined as the adsorbed amount of the total of straight-chain alkane and mono-methyl branched alkane divided by the absorbed amount of the total of higher-branched alkane. High adsorption selectivity leads to smaller equipment volumes, and lower capital and energy requirements.

Classes IPC  ?

• C07C 7/13 - Purification, séparation ou stabilisation d'hydrocarburesEmploi d'additifs par adsorption, c.-à-d. purification ou séparation d'hydrocarbures à l'aide de solides, p. ex. à l'aide d'échangeurs d'ions par la technique du tamis moléculaire
• C07C 9/10 - Hydrocarbures saturés acycliques de un à quatre atomes de carbone à quatre atomes de carbone
• C07C 9/14 - Hydrocarbures saturés acycliques de cinq à quinze atomes de carbone
• C07C 9/18 - Hydrocarbures ramifiés à cinq atomes de carbone
• C07C 9/22 - Hydrocarbures saturés acycliques de plus de quinze atomes de carbone
• C10G 25/03 - Raffinage des huiles d'hydrocarbures, en l'absence d'hydrogène, au moyen d'absorbants ou d'adsorbants solides avec échangeur d'ions avec des alumino-silicates cristallins, p. ex. avec des tamis moléculaires
• C10G 53/08 - Traitement des huiles d'hydrocarbures, en l'absence d'hydrogène, par plusieurs procédés de raffinage uniquement par plusieurs étapes en série comprenant au moins une étape d'absorption ou d'adsorption

Abrégé

The invention pertains to a process for manufacturing a glycerol-tricarboxylic acid polyester foam which comprises the steps of combining glycerol and a tri-carboxylic acid to provide a liquid reaction mixture and contacting the reaction mixture with a substrate under polymerization conditions, wherein the substrate has a top layer comprising one or more of metal, metal oxide, and metal halide. The invention also pertains to a glycerol-tricarboxylic polyester foam, in particular a glycerol-citric acid polyester foam, which has a closed cell foam structure wherein at least 90 vol.% of the foam, preferably at least 95% of the foam, is built up from cells having a diameter below 2 mm. The foamed polyester of the present invention is "green", biodegradable, and non-toxic, and can be cleanly combusted. It finds application in, int. al., packaging materials, insulation materials, and materials with a short life cycle.

Classes IPC  ?

• C08G 63/12 - Polyesters dérivés soit d'acides hydroxycarboxyliques, soit d'acides polycarboxyliques et de composés polyhydroxylés dérivés d'acides polycarboxyliques et de composés polyhydroxylés
• C08G 83/00 - Composés macromoléculaires non prévus dans les groupes
• C08J 9/34 - Caractéristiques chimiques de la fabrication d'objets constitués par un cœur macromoléculaire sous forme de mousse avec une couche superficielle macromoléculaire d'une densité supérieure à celle du cœur
• C08J 9/02 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement utilisant des gaz de gonflage produits par la réaction des monomères ou par des agents de modification durant la préparation ou la modification des macromolécules

Abrégé

The invention relates to a process for the oxidation of water under formation of molecular oxygen, comprising a step wherein a compound according to Formula I or a compound according to Formula II is reacted with water. The invention also relates to a compound according to Formula I and to a compound according to Formula II. The invention further relates to a solid material comprising a compound according to Formula I, and to a solid material comprising a compound according to Formula II. In particular, the invention relates to an electrode comprising a compound according to Formula I, and to an electrode comprising a compound according to Formula II.

Classes IPC  ?

• C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
• C01B 13/02 - Préparation de l'oxygène

Abrégé

An activatable device (15) is provided which comprises a device (13) and an activatable imaging probe (1) attached to it. The probe comprises a chromophore (3) and an interaction moiety (5) attached to the chromophore. By interaction of a target (23) with the interaction moiety the optical properties of the probe are altered. An activatable imaging probe for attachment to such activatable device is also provided.

Classes IPC  ?

• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Ά composite material comprising 10-98 wt. % of a bio-based particulate or fibrous filler and at least 2 wt. % of a polyester derived from an aliphatic polyalcohol with 2-15 carbon atoms and a polyacid, wherein the polyacid comprises at least 10 wt. % of tricarboxylic acid. Preferably, the filler is in the form of particles, fibers, and/or random or non-random layers. A plant-based filler may be used, in particular a cellulosic or lignocellulosic material, more in particular one or more materials selected from wood chips, wood flakes, sawdust, pulp, e.g., pulp of (recycled) paper or other fiber pulp, and plant-derived fibers such as cotton, linen, flax, and hemp. An animal- derived filler, in particular an animal-derived fiber such as wool, hair, silk, or feathers may also be used. Preferably the polyacohol is selected from one or more of glycerol, sorbitol, xylitol, mannitol, 1, 2-propane diol, 1,3- propane diol, and 1, 2-ethane diol, in particular glycerol. The polyacid preferably is an aliphatic diacid or triacid with 3-15 carbon atoms. Examples of suitable acids include citric acid, succinic acid, and itaconic acid. The composite material according to the invention has fire- retardant properties, which makes it particularly suitable for applications where fire-retardancy is an issue.

Classes IPC  ?

• C08J 5/24 - Imprégnation de matériaux avec des prépolymères pouvant être polymérisés en place, p. ex. fabrication des "prepregs"
• C09D 167/00 - Compositions de revêtement à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleCompositions de revêtement à base de dérivés de tels polymères
• C09D 167/02 - Polyesters dérivés d'acides dicarboxyliques et de composés dihydroxylés
• C09J 167/00 - Adhésifs à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleAdhésifs à base de dérivés de tels polymères
• C09J 167/02 - Polyesters dérivés d'acides dicarboxyliques et de composés dihydroxylés
• C08J 7/04 - Revêtement
• C09J 5/06 - Procédés de collage en généralProcédés de collage non prévus ailleurs, p. ex. relatifs aux amorces comprenant un chauffage de l'adhésif appliqué

Abrégé

Laminate comprising a carrier and a coating layer, wherein the coating layer is applied over at least part of the carrier, the coating layer comprising a polyester derived from an aliphatic polyalcohol with 2-15 carbon atoms and a polyacid, the coating layer having a thickness in the range of 10-4000 microns, wherein the aliphatic polyalcohol contains at least 50 mol. % of glycerol and the polyacid contains at least 30 wt. % of tricarboxylic acid. Optionally a second carrier may be applied over at least part of the coating layer. If so desired, a further coating layer is applied over at least part of the second carrier, with optional further carrier-coating stacks applied over the further carrier. Preferably the tricarboxylic acid is citric acid. The laminate according to the invention may be, e.g., a multiplex-type material. The laminate according to the invention has fire-retardant properties which makes it particularly suitable for use in applications where fire-retardancy is an issue.

Classes IPC  ?

• C09D 167/00 - Compositions de revêtement à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleCompositions de revêtement à base de dérivés de tels polymères
• C09D 167/02 - Polyesters dérivés d'acides dicarboxyliques et de composés dihydroxylés
• C09J 167/00 - Adhésifs à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleAdhésifs à base de dérivés de tels polymères
• C09J 167/02 - Polyesters dérivés d'acides dicarboxyliques et de composés dihydroxylés
• C08J 7/04 - Revêtement
• C09J 5/06 - Procédés de collage en généralProcédés de collage non prévus ailleurs, p. ex. relatifs aux amorces comprenant un chauffage de l'adhésif appliqué

Abrégé

A composite material comprising 20-98 wt.% of a synthetic particulate or fibrous filler and at least 2 wt.% of a polyester derived from an aliphatic polyalcohol with 2-15 carbon atoms and a polyacid, wherein the alcohol comprises at least 50 mole% of glycerol, and the acid comprises at least 50 wt.% of tricarboxylic acid. Preferably, the filler is in the form of particles, fibers, and/or random or non-random layers. Preferably, the filler is based on one or more of ceramic, including glass, in particular glass fibers, polymer, in particular polymer fibers, and carbon, in particular carbon fibers. The use of glass fiber based sheet-like material as filler is a particular embodiment of the invention. The composite material according to the invention has fire- retardant properties, which makes it particularly suitable for applications where fire-retardancy is an issue.

Classes IPC  ?

• C08J 5/24 - Imprégnation de matériaux avec des prépolymères pouvant être polymérisés en place, p. ex. fabrication des "prepregs"
• C09D 167/00 - Compositions de revêtement à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleCompositions de revêtement à base de dérivés de tels polymères
• C09D 167/02 - Polyesters dérivés d'acides dicarboxyliques et de composés dihydroxylés
• C09J 167/00 - Adhésifs à base de polyesters obtenus par des réactions créant une liaison ester carboxylique dans la chaîne principaleAdhésifs à base de dérivés de tels polymères
• C09J 167/02 - Polyesters dérivés d'acides dicarboxyliques et de composés dihydroxylés
• C08J 7/04 - Revêtement
• C09J 5/06 - Procédés de collage en généralProcédés de collage non prévus ailleurs, p. ex. relatifs aux amorces comprenant un chauffage de l'adhésif appliqué

Abrégé

A testing system with a control unit (10) connected to a plurality of sending and or receiving transducers (5, 6). In combination, the control unit (10) and transducers (5, 6) are arranged to receive a current signal originating from the sample, to calculate a fidelity index η by correlating a tail part of the current signal with a reference signal, and to compare the fidelity index η with a threshold value ηthr

Classes IPC  ?

• G01N 29/14 - Recherche ou analyse des matériaux par l'emploi d'ondes ultrasonores, sonores ou infrasonoresVisualisation de l'intérieur d'objets par transmission d'ondes ultrasonores ou sonores à travers l'objet utilisant des techniques d'émission acoustique
• G01N 29/50 - Traitement du signal de réponse détecté en utilisant des techniques d'autocorrélation ou des techniques d'intercorrélation
• G01N 29/44 - Traitement du signal de réponse détecté

Abrégé

The invention pertains to a process for producing a glycerol tri-carboxylic acid polyester foam which comprises the steps of combining glycerol and a tri-carboxylic acid in the liquid phase to provide a reaction mixture, and keeping the reaction mixture at a temperature of between 80°C and 130°C from the start of the reaction until a conversion of at least 90% is obtained. The foamed polyester of the present invention is "green", biodegradable, and non-toxic, and can be cleanly combusted. It finds application in, int. al., packaging materials, insulation materials, and materials with a short life cycle.

Classes IPC  ?

• C08G 63/12 - Polyesters dérivés soit d'acides hydroxycarboxyliques, soit d'acides polycarboxyliques et de composés polyhydroxylés dérivés d'acides polycarboxyliques et de composés polyhydroxylés

Abrégé

A method for detecting a person's interest direction, wherein a processor performs the steps of: determine in real time an interest vector of a person from video data captured by a video camera; determine in real time a salient peak closest to the determined interest vector; determine in real time a saliency-corrected interest vector from the eyes of said person to said closest salient peak; determine in real time the deviation between the determined interest vector and the determined saliency-correctedinterestvector; determine in real time further interest vectors of said person from said video data; and calculate in real time recalibrated interest vectors by using a calibration error value calculated from said determined deviation.

Classes IPC  ?

• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur

Abrégé

The invention pertains to a diphosphine-transition metal complex comprising a diphosphine-transition metal ligand that is covalently bonded to an insoluble mesoporous support having an average pore diameter of from 4.5 nm to 50 nm, characterized in that the ligand as attached to the support has the formula: wherein R is aryl, C1-C4 alkyl, aralkyl, alkylaryl; C1-C4 alkoxy, aralkoxy, or alkylaryloxy; P is a phosphorous atom; M is a transition metal; X is a bond, CH2, 0, S or NH2; Y is C or N; A is a linking moiety which is bonded to the mesoporous support; the ring formed by X, Y and the two aromatic rings is a 5- or 6-membered ring; and wherein the aromatic rings may be unsubstituted or substituted. The invention further relates to the use of the diphosphine- transition metal complex as a catalyst in a reaction selected from hydroformylation, hydrogenation, carbonylation or carbon-carbon coupling.

Classes IPC  ?

• C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
• C07F 19/00 - Composés métalliques couverts par plus d'un des groupes principaux
• B01J 31/24 - Phosphines
• C07C 45/49 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par réaction avec le monoxyde de carbone

Abrégé

The present invention relates to a stereoregular copolymer having the general formula 1: (-CHR1-)n wherein the copolymer comprises a chain of n carbon atoms, each carbon atom bearing a R1 group, each R1 group being independently selected from the group consisting of: -H and hydrocarbyl-groups having between 1 and 50 carbon atoms and optionally one or more hetero atoms, and wherein the copolymer comprises at least two different R1 groups, and wherein n is an integer ranging from 50 to 1000000. The present invention also relates to a method for preparing such copolymers.

Classes IPC  ?

• C08F 2/00 - Procédés de polymérisation

Abrégé

A photovoltaic device is provided comprising a thin-film of an energy conversion material. The energy conversion material includes one or more quantum structures, where the quantum structures comprise a semiconductor material having an indirect band-gap in the bulk. The average size of the quantum structures is selected such that a direct and an indirect band-gaps are modified in the semiconductor material such that the direct band-gap provides charge carrier generation when the quantum structures are exposed to light.

Classes IPC  ?

• H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
• H01L 31/028 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des éléments du groupe IV de la classification périodique

Abrégé

The invention relates to a method for imaging an object, comprising the illumination of the object, and the detection of light coming from an area where the object is located and, based on the detected light, forming the image, with the illumination of the object taking place by distinguishing image elements in an imaging plane or space, and by separately illuminating the object parts corresponding with these image elements, while simultaneously registering the applied illumination dose of these object parts, and wherein the image is subsequently constructed by assembling the image elements corresponding with the illuminated object parts, subject to the light output and illumination doses pertaining to those image elements, wherein the illumination dose of each separate object part depends at least on a light output and/or illumination dose of another object part or several other object parts.

Classes IPC  ?

• G02B 21/06 - Moyens pour éclairer un échantillon
• G02B 27/34 - Repères fiduciels ou échelles de mesure à l'intérieur du système optique éclairés

Abrégé

A process of producing an organic compoundand/or an intermediary compound as defined herein by feeding carbon dioxide to a culture of a cyanobacterial cell and subjecting said culture to light, wherein said cell is capable of expressing a nucleic acid molecule, wherein the expression of said nucleic acid molecule confer on the cell the ability to convert a glycolytic intermediate into said organic compound and/or into said intermediary compound and wherein said nucleic acid molecule is under the control of a regulatory system which responds to a change in the concentration of a nutrient in said culture.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• C07K 14/195 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries
• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora
• C12P 5/02 - Préparation des hydrocarbures acycliques
• C12P 7/04 - Préparation de composés organiques contenant de l'oxygène contenant un groupe hydroxyle acycliques
• C12P 7/06 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique
• C12P 7/16 - Butanols
• C12P 7/18 - Polyols
• C12P 7/20 - Glycérol
• C12P 7/24 - Préparation de composés organiques contenant de l'oxygène contenant un groupe carbonyle
• C12P 7/28 - Produits contenant de l'acétone
• C12P 7/56 - Acide lactique

Abrégé

The invention relates to a coordination complex system comprising a ligand having the formula: R1-SO2-NH-P (XR2)2 (1a); or R1-SO2-N=PH (XR2)2 (1b); or R1-SO(OH)=N-P(XR2)2 (1c); wherein X is independently O, S, NH, or a bond; R1 and R2 are independently selected from hydrogen and substituted or unsubstituted alkyl or aryl; wherein at least one equivalent of the ligand is complexed to an equivalent of a metal selected from a transition metal and lanthanide. The invention also relates to the use of said coordination complexes as catalysts in the hydrof ormylation, hydrogenation, transfer hydrogenation, hydrocyanation, polymerization, isomerization, carbonylation, cross-coupling, metathesis, CH activation, allylic substitution, aldol condensation, or Michael addition.

Classes IPC  ?

• C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
• B01J 31/12 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des composés organométalliques ou des hydrures métalliques
• C07B 53/00 - Synthèses asymétriques

Abrégé

The present invention relates to methods for inducing changes in epigenetic gene control in a chromatin domains in eukaryotic cells, and to nucleic acid constructs and host cells for use in such methods. The methods use nucleic acid constructs that are preferablyintegrated at a predetermined chromatin region of the host cell's genome, which nucleic acid construct comprise binding sites for a DNA-binding protein. Proteins that induces or are suspected to induce epigenetic gene control may then be targetedtothe integrated nucleic acid construct by means of fusion to the DNA binding protein. The targeting protein that induces or is suspected to induce epigenetic gene control to the integrated nucleic acid construct then allows to determine its effects on chromatin structure, gene expression, and epigenetic status of the chromatin locus.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression

Abrégé

The present invention discloses a method for the preparation of a polymer from vinyl group-containing monomers comprising the step of polymerizing the vinyl group-containing monomers in the presence of a metal catalyst having a moiety M2+(Y)4(X)2, wherein M is a transition metal selected from the group of Ru, Mn, Fe, Co, Zr, Rh and Os, each Y independently is a nitrogen-containing aromatic mono-ring ligand, at least one ligand Y being substituted on at least one position with a carbon-containing substituent and, optionally, either two or four ligands Y being covalently bonded to each other in pairs, and X is selected from H2O, CH3CN, (CH3) 2S0, NH3, and a mono-, di- or tri (C1-C4) -alkyl amine. The catalyst advantageously enables the synthesis of polymers with high molecular weights and low polydispersities from monomer compounds containing a vinyl group. The present invention further discloses specific novel ruthenium catalysts.

Classes IPC  ?

• C08F 12/08 - Styrène
• C08F 4/80 - MétauxHydrures métalliquesComposés organiques de métalLeur utilisation comme précurseurs de catalyseurs choisis parmi les métaux non prévus dans le groupe choisis parmi les métaux du groupe du fer ou les métaux du groupe du platine

Abrégé

The invention is directed to a process for the production of certain phosphorous, namely urea, thio-urea and sulphonamide phosphorous compounds. The present invention provides a process for the production of phosphorous compounds which process allows an easy and effective separation of the reaction products from impurities by applying a solid alkaline ion-exchange resin.

Classes IPC  ?

• C07F 9/141 - Esters des acides phosphoreux
• C07F 9/6574 - Esters des oxyacides du phosphore

Abrégé

The invention is directed to a method by which the bonding strength between zirconia-based materials and other materials can be improved, and to zirconia-based materials obtainable by this method and which have improved surface properties. According to the present invention there is provided a method for increasing the bond strength between stabilized zirconia and another material, wherein said stabilized zirconia comprises ZrO2 and at least one stabilizing compound. The method of the invention results in stabilized zirconia which has an improved bond strength with other materials, which bond strength is stable with time. The surface modified stabilized zirconia of the invention can be used in prosthetic restorations, implants, solid electrolytes, fuel cells, oxygen sensors, cutting abrasives, or electrical insulators.

Classes IPC  ?

• C04B 37/00 - Liaison des articles céramiques cuits avec d'autres articles céramiques cuits ou d'autres articles, par chauffage
• C04B 35/486 - Céramiques fines
• C04B 41/53 - Post-traitement des mortiers, du béton, de la pierre artificielle ou des céramiquesTraitement de la pierre naturelle impliquant l'enlèvement d'une partie des matières de l'objet traité
• C04B 41/45 - Revêtement ou imprégnation
• A61C 13/09 - Dents faites de plusieurs couches
• A61C 5/08 - Couronnes dentaires; Leur fabrication; Fixation des couronnes dans la bouche
• A61K 6/00 - Préparations pour la technique dentaire

Abrégé

The present invention describes a novel cross-linker, a method for preparing one or more cross-linked biomolecules, biomolecular complexes of two or more biomolecules, a method for preparing cross-linked fragments from such cross-linked biomolecules and/or biomolecular complexes, a method for cleavage and reduction of such cross-linked biomolecules and/or biomolecular complexes, a method for identifying cross-links in such cross-linked biomolecules and/or biomolecular complexes, as well as a method for determining relative amounts of cross-links in a biomolecule or biomolecular complex in two or more samples.

Classes IPC  ?

• C07D 207/416 - Pyrrolidines-2, 5 diones avec des hétéro-atomes ou des atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux autres atomes de carbone du cycle

Abrégé

Method of characterizing an image comprising: defining one or more image areas of the image; analyzing color and/or intensity transitions within the image area of a predefined color basis; creating a density profile of said transitions in said image area; and fitting said density profile to a predefined parametrization function According to the method said density profile is characteristic for an image and can be used for image characterization purposes.

Classes IPC  ?

• G06K 9/64 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques utilisant des comparaisons ou corrélations simultanées de signaux images avec une pluralité de références, p.ex. matrice de résistances
• G06K 9/46 - Extraction d'éléments ou de caractéristiques de l'image

Abrégé

A method for making dihydroxyacetone phosphate (DHAP) comprising treating dihydroxyacetone with a bacterial acid phosphatase in the presence of pyrophosphate. The invention further pertains to a method for making, preferably in one pot, stereospecif ically a compound of the formula: R-C*H(OH) -C*H(OH) -CO-CH2-OH comprising the steps: a) treating dihydroxyacetone with a bacterial acid phosphatase in the presence of pyrophosphate to make dihydroxyacetone phosphate; b) treating the dihydroxyacetone phosphate with R-CHO and an aldolase, wherein R-CHO is any aldehyde, preferably R is selected from H, unsubstituted or substituted (cyclo) alkyl , and a carbohydrate moiety, and C* stands for a chiral carbon atom to a phosphate of the formula: R-C*H(0H) -C*H(OH) -CO-CH2-OPO3H2; and c) dephosphorylating the phosphate of step b) by treating said phosphate with a bacterial acid phosphatase.

Classes IPC  ?

• C12P 7/28 - Produits contenant de l'acétone
• C12P 19/26 - Préparation d'hydrates de carbone contenant de l'azote
• C12P 17/12 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle l'azote comme unique hétéro-atome du cycle contenant un hétérocycle à six chaînons

Abrégé

Method of characterizing an object comprising: defining one or more image areas of the object; analyzing color and/or intensity transitions within the image area of a predefined color basis; creating a density profile of said transitions in said image area; and fitting said density profile to a predefined parametrization function According to the method said density profile is characteristic for an object and can be used for object recognition purposes.

Classes IPC  ?

• G06K 9/64 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques utilisant des comparaisons ou corrélations simultanées de signaux images avec une pluralité de références, p.ex. matrice de résistances
• G06K 9/46 - Extraction d'éléments ou de caractéristiques de l'image