ST VINCENT'S HOSPITAL (MELBOURNE) LIMITED (Australie)
Inventeur(s)
Choong, Peter, Fook Meng
Duchi, Serena
Onofrillo, Carmine
Wallace, Gordon, George
Beirne, Stephen, Thomas
Gambhir, Sanjeev
Gailer, Daniel, John
Di Bella, Claudia
Abrégé
An apparatus for use in preparation of a composition for treatment or repair or regeneration of tissue comprises a collection vessel configured to receive harvested tissue and at least one filter element located inside the collection vessel. The apparatus is configured to be received in a centrifuge to separate a Stromal Vascular Fraction (SVF) from the harvested tissue within the collection vessel. At least a portion or extract of the SVF separated from the harvested tissue in the apparatus is used in preparation of a treatment composition comprising a mixture of SVF or extract and a polymer composition for treatment or repair or regeneration of the tissue.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
Antibody or binding fragment thereof, fusion protein, or pharmaceutical composition directed against misfolded SOD1 epitope, or nucleic acid encoding the antibody or binding fragment thereof, fusion protein, or pharmaceutical composition, are described. Also provided are methods for using and manufacturing such antibody or binding fragment thereof, fusion protein, nucleic acid, or pharmaceutical composition, as well as methods of their use for treating a disorder in a human subject in need thereof.
C07K 16/40 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre des enzymes
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 47/55 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique l’agent de modification étant aussi un agent pharmacologiquement ou thérapeutiquement actif, c.-à-d. le conjugué entier étant un co-médicament, p. ex. un dimère, un oligomère ou un polymère de composés pharmacologiquement ou thérapeutiquement actifs
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
The present invention relates to a probe (1; 1a; 1b) for detecting ionizing radiation. The probe (1; 1a; 1b) comprises an elongated flexible support (10) and a detector apparatus (20; 20a; 20b), which is coupled to the flexible support (10) near one end (11) thereof. The flexible support (10) comprises a plurality of electrically conductive tracks (19a-f) coupled to corresponding electrical terminals (24a-f) of the detector apparatus (20; 20a; 20b) to allow the exchange of electrical signals between the apparatus and a processing device (40). Advantageously, the detector apparatus (20; 20a; 20b) comprises a sensor (21) adapted to generate a signal indicative of an intensity of ionizing radiations hitting the detector apparatus (20; 20a; 20b), and a processing module (22) adapted to condition the signal generated by the sensor (21).
Australian Nuclear Science and Technology Organisation (Australie)
University of Wollongong (Australie)
Inventeur(s)
Safavi-Naeini, Mitra
Chacon, Andrew Stephen
Abrégé
An irradiation method and system for irradiating a target volume, the method comprising: providing thermal neutron absorbing nuclides (such as in the form of a high neutron cross-section agent) at the target volume; and producing neutrons by irradiating nuclei in or adjacent to the target volume with a beam of particles consisting of any one or more of protons, deuterons, tritons and heavy ions, thereby prompting production of the neutrons through non-elastic collisions between the atoms in the path of the beam (including the target) and the particles. The neutron absorbing nuclides absorb neutrons produced in the non-elastic collisions, thereby producing capture products or fragments that irradiate the target volume.
H05H 13/10 - Accélérateurs comprenant une ou plusieurs sections d'accélération linéaire et des aimants de courbure ou des dispositifs analogues pour faire revenir les particules chargées sur une trajectoire parallèle à la première section d'accélération, p. ex. microtrons
SOUTH EASTERN SYDNEY LOCAL HEALTH DISTRICT (Australie)
THE UNIVERSITY OF WOLLONGONG (Australie)
Inventeur(s)
You, Jingjing
Sutton, Gerard
Overmass, Morgan
Lovicu, Frank
Wallace, Gordon
Abrégé
The present invention relates to compositions suitable for the delivery of agents to biological targets such as tissues and cells and/or capable of promoting the growth and/or proliferation of cells, and methods for the production thereof. Specifically, a printable collagen bioink comprising type IV collagen is used to produce crosslinked collagen gels comprising mammalian cells, such as endothelial or epithelial cells, for corneal regeneration.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
Disclosed herein is a structure comprising: a gate electrode, a dielectric layer, and a planar layer of a topological material being separated from the gate electrode by at least the dielectric layer, and having a contact interface with the dielectric layer to generate an electric field-controlled Rashba spin-orbit interaction on application of an electric field thereto, wherein the topological material exhibits a topological phase transition between a trivial state and a non-trivial state at a critical electric field strength on application of the electric field, wherein the gate electrode is configured to apply the electric field across the planar layer in a direction perpendicular to a plane of the planar layer; and wherein the topological material exhibits a change in bandgap, in the presence of the electric field, having a spin-dependent contribution represented by a proportionality constant αR and a non-spin-dependent contribution represented by a proportionality constant αv; and wherein αR>αv/3.
An electrostimulatable 3-dimensional (3D) electrogel scaffold comprising piezoelectric nanoparticles uniformly dispersed throughout a homogenous hydrogel polymer matrix, wherein the hydrogel polymer matrix is gelled and comprises crosslinked alginate, carboxymethyl-chitosan and agarose polymers.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
An apparatus (1) determines body movement and including a chamber (2) having an internal volume, wherein the chamber is configured to vary in internal volume in response to body movement. The apparatus (1) includes a sensor module (3) configured to detect variances in the internal volume of the chamber (2).
A61F 2/70 - Moyens d'actionnement ou de commande électriques
A61F 4/00 - Procédés ou dispositifs permettant à des patients ou à des personnes handicapées de commander un appareil ou un dispositif ne faisant pas partie du corps
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
Disclosed herein, in part, are nanometers-thin and uniformly thick polymer films comprising an electrochemically polymerized polymer and a polyelectrolyte. Methods of preparing said nanometers-thin and uniformly thick polymer films are also provided.
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
C08L 65/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions contenant des dérivés de tels polymères
C09D 165/00 - Compositions de revêtement à base de composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions de revêtement à base de dérivés de tels polymères
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
H10K 30/00 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Paper; paper articles of stationery; cardboard; cardboard
packaging; printed matter including newspapers, magazines,
periodicals, journals, pamphlets, books; photographs;
promotional displays being banners of paper, posters and
flags of paper; stationery; instructional and teaching
materials; teaching manuals; teaching materials for
education; educational materials (other than apparatus) for
use in teaching; certificates. Advertising and promotional services, including the
advertising of educational and training courses and research
services; business administration, consultancy and
management services; business research; compilation of
information; services consisting of the compilation of
business and statistical data; business management services;
business management services relating to research and
development, commercialisation of technology, processes and
products and technology transfer; business management and
administration services for the provision of educational
courses and research services; business services relating to
technology transfer; retail services including online retail
services of clothing, books, stationery, bags, computers and
computer accessories; career counselling (employment advice
and information). Academies (education); academy education services; adult
education; advisory services relating to education and
training; arranging of exhibitions for educational and
training purposes; arranging and conducting of workshops
(training); conducting of educational conferences, courses;
conducting of exhibitions for educational and training
purposes; conducting training seminars and workshops;
consultancy services relating to education and training;
design of educational courses, examinations and
qualifications; dissemination of educational material;
education and training information; education and training
services; educational advisory, assessment, examination,
instruction and research services; educational institute
services; educational seminars; health education;
information services relating to education; international
student exchange programmes; library services; management of
education services and events; mentoring (education and
training); organisation of training courses; practical
training (demonstration); providing facilities for
educational purposes; providing information, including
online, about education, training, entertainment, sporting
and cultural activities; provision of educational courses;
provision of facilities for education; provision of
training; provision of training facilities; provision of
education services via an online forum; publication of
educational texts and materials; setting of educational
standards; sports education and training services; training;
vocational guidance (education or training advice);
vocational education and training services; university
education services; sporting and cultural activities and
services; alumni association services being university
services; charitable services, namely education, training
and mentoring. Advisory services relating to scientific, medical,
engineering, social science, metallurgy, mining, building
and technical research; computer and software programming
services; laboratory research; laboratory services
(scientific research or analysis); management of scientific
research projects; medical research including scientific
research for medical purposes and in relation to disease,
gut health, mental health, nutrition and ageing; preparation
of reports and information relating to scientific and
technical research; preparation of statistics for scientific
research; providing information, including online, about
industrial analysis and research services; research and
development (for others); research in all fields of science
and industry, including biology, biotechnology, chemistry,
design, engineering, medicine, molecular sciences, physics,
safety and technology; research services in all fields of
science including marine science and policy; research,
engineering and technical consultancy for industry;
scientific, technical, engineering, technical data and
computer analysis services; social science research
services; social science research services in the fields of
health, environment, sustainability, ageing and early
childhood; research services in the fields of metallurgy and
mining; building research services; building research
services relating to infrastructure, sustainable buildings
and energy storage; clinical trials; design of medical
apparatus; research and development of new products for
others; research relating to computer programming, computer
security and computers; research relating to demographics
for scientific purposes; technological consultancy and
preparation of reports relating to the transfer of technical
(including data, knowledge, protocols, policies and
research) and professional know-how relating to all the
foregoing.
ST VINCENT'S HOSPITAL (MELBOURNE) LIMITED (Australie)
UNIVERSITY OF WOLLONGONG (Australie)
SWINBURNE UNIVERSITY OF TECHNOLOGY (Australie)
THE UNIVERSITY OF MELBOURNE (Australie)
Inventeur(s)
Choong, Peter, F.M.
Gambhir, Sanjeev
Wallace, Gordon, George
Duchi, Serena
Onofrillo, Carmine
O’connell, Cathal, D.
Di Bella, Claudia
Moulton, Simon, Edward
Abrégé
A functionalised polymer comprising a polymer partially functionalised with: a plurality of photocrosslinkable moieties linked to the polymer, each photocrosslinkable moiety comprising a reactive functionality capable of photocrosslinking; and a plurality of cell adhesion moieties each linked to the polymer via a linker, each cell adhesion moiety comprising a cell adhesion motif, and wherein the functionalised polymer further comprises a plurality of functional groups capable of ionic crosslinking with an ionic crosslinking agent. A method for forming a liquified polymer composition comprising cells from a tissue sample, the method comprising: providing a tissue sample comprising cells; contacting the sample with the functionalised polymer in binding conditions, said binding conditions being conditions that enable binding of cells in the sample to the functionalised polymer, so that said cells are bound to the functionalised polymer; culturing the cells bound to the polymer under conditions and for a time that allows the cell number to increase; providing conditions to induce a solid to liquid phase change of the functionalised polymer; thereby forming a liquified polymer composition comprising cells from a tissue sample.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
Disclosed is a method of fabricating an anode for a lithium-ion battery, including milling a mixture of nano-silicon, one or more carbonaceous materials and one or more solvents, wherein the mixture is retained as a wet slurry during milling. The mixture is carbonised to produce a silicon thinly coated with carbon (Si@C) material. Further milling occurs of a second mixture of the Si@C material, one or more graphite, one or more second carbonaceous materials and one or more second solvents, wherein the second mixture is retained as a second wet slurry during milling. The second mixture is carbonised to produce a Si@C/graphite/carbon material. The anode is formed from the Si@C/graphite/carbon material.
H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
Disclosed is an electrochemical cell, system and method for capturing carbon dioxide. In an example the electrochemical mineral carbonation cell comprises a gas permeable cathode and carbon dioxide gas is able to pass into an outer surface of and at least partially through the gas permeable cathode to react with a liquid catholyte. A voltage difference is able to be applied between the gas permeable cathode and an anode. A membrane is positioned between the gas permeable cathode and the anode. The liquid catholyte is positioned between the gas permeable cathode and the membrane and the liquid catholyte includes mineral ions, for example sodium, potassium, lithium or calcium ions, a liquid anolyte is positioned between the anode and the membrane. In operation of the cell, the liquid catholyte flows along an inner surface of the gas permeable cathode, and a carbonate mineral, for example sodium carbonate, potassium carbonate, lithium carbonate or calcium carbonate, is produced at or near the inner surface of the gas permeable cathode and is at least partially transported away from the inner surface of the gas permeable cathode by the liquid catholyte flow.
Board of Regents, The University of Texas System (USA)
University of Wollongong (Australie)
Inventeur(s)
Romero-Ortega, Mario I.
Wallace, Gordon G.
Gonzalez-Gonzalez, Maria
Jalili, Rouhollah Ali
Abrégé
The present disclosure provides methods of making and applying metalized graphene fibers in bioelectronics applications. For example, platinized graphene fibers may be used as an implantable conductive suture for neural and neuro-muscular interfaces in chronic applications. In some embodiments, an implantable electrode includes a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene-fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating.
SOUTH EASTERN SYDNEY LOCAL HEALTH DISTRICT (Australie)
THE UNIVERSITY OF WOLLONGONG (Australie)
Inventeur(s)
You, Jingjing
Sutton, Gerard
Overmass, Morgan
Lovicu, Frank
Wallace, Gordon
Abrégé
The present invention relates to compositions suitable for the delivery of agents to biological targets such as tissues and cells and/or capable of promoting the growth and/or proliferation of cells, and methods for the production thereof. Specifically, a printable collagen bioink comprising type IV collagen is used to produce crosslinked collagen gels comprising mammalian cells, such as endothelial or epithelial cells, for corneal regeneration.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux
B33Y 70/10 - Composites de différents types de matériaux, p. ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
B33Y 80/00 - Produits obtenus par fabrication additive
C09D 11/04 - Encres d’imprimerie à base de protéines
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
H01L 27/00 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun
An electrostimulatable 3-dimensional (3D) electrogel scaffold comprising piezoelectric nanoparticles uniformly dispersed throughout a homogenous hydrogel polymer matrix, wherein the hydrogel polymer matrix is gelled and comprises crosslinked alginate, carboxymethyl-chitosan and agarose polymers.
An implantable device and methods for preparing and implanting said device into a subject for use in treating a medical condition when implanted therein is disclosed. The device comprises at least one coaxial fibre of a hydrophilic polymer and a hydrophobic polymer, wherein at least one of said polymers is loaded with an agent that is active towards treating the medical condition.
A61L 29/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
A61K 31/7068 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées ayant des groupes oxo liés directement au cycle pyrimidine, p. ex. cytidine, acide cytidylique
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à quatre chaînons, p. ex. taxol
Disclosed is an electro-synthetic or electro-energy cell, and method of operation, comprising a first gas diffusion electrode configured to generate a first gas and be in contact with and adjacent to a first gas body comprising the first gas, and a second gas diffusion electrode configured to generate a second gas and be in contact with and adjacent to a second gas body comprising the second gas. A porous capillary spacer is positioned between the first gas diffusion electrode and the second gas diffusion electrode. The porous capillary spacer is configured to be filled with a liquid electrolyte and to confine the liquid electrolyte in the porous capillary spacer by a capillary effect and whereby the liquid electrolyte has a maximum column height of more than 0.4 cm.
Disclosed is a method of operating an electro-synthetic or electro-energy cell to perform an electrochemical reaction. Also disclosed is an electro-synthetic or electro-energy cell comprising a reservoir containing a liquid electrolyte, a first gas diffusion electrode, and a second electrode. A porous capillary spacer is positioned between the first gas diffusion electrode and the second electrode. Preferably, the porous capillary spacer has an end positioned within the reservoir and in liquid contact with the liquid electrolyte. The method comprises the steps of contacting the first gas diffusion electrode and the second electrode with the liquid electrolyte, and applying or generating a voltage across the first gas diffusion electrode and the second electrode.
Disclosed are zero-gap electrochemical cell architectures that employ molecular-level capillary and/or diffusion and/or osmotic effects to minimize the need for macroscopic external management of the electrochemical cell. Preferably, these effects intrinsically respond to the electrochemical cell conditions, making them self-regulating. In one example is disclosed an electro-synthetic or electro-energy cell, and method of operation, comprising a reservoir for containing a liquid electrolyte, a first gas diffusion electrode positioned outside of the reservoir, and a second electrode positioned outside of the reservoir. A porous capillary spacer is positioned between the first gas diffusion electrode and the second electrode, the porous capillary spacer having an end that extends into the reservoir. Preferably, the porous capillary spacer is able to fill itself with the liquid electrolyte when the end of the porous capillary spacer is in liquid contact with the liquid electrolyte in the reservoir.
Disclosed is an electro-synthetic water electrolysis cell, and method of operation, comprising a first gas diffusion electrode configured to generate a first gas and be in direct contact with a first gas body comprising the first gas, and a second electrode. A porous capillary spacer is configured to be filled with a liquid electrolyte and is positioned between the first gas diffusion electrode and the second electrode. Preferably, an average pore diameter of the porous capillary spacer is more than 2 µm (microns).
A composite thermoelectric material (100) comprising: a host matrix (102) comprising a semiconducting thermoelectric material; and amorphous particles (104) dispersed throughout the host matrix (102), wherein the host matrix (102) includes a polycrystalline structure (106) nucleated by the amorphous particles (104).
H01L 35/16 - Emploi d'un matériau spécifié pour les bras de la jonction utilisant des compositions inorganiques comprenant du tellure, du sélénium, ou du soufre
H01L 35/18 - Emploi d'un matériau spécifié pour les bras de la jonction utilisant des compositions inorganiques comprenant de l'arsenic, de l'antimoine, ou du bismuth
H01L 35/22 - Emploi d'un matériau spécifié pour les bras de la jonction utilisant des compositions inorganiques comprenant des composés contenant du bore, du carbone, de l'oxygène ou de l'azote
H01L 35/32 - DISPOSITIFS À SEMI-CONDUCTEURS; DISPOSITIFS ÉLECTRIQUES À L'ÉTAT SOLIDE NON PRÉVUS AILLEURS - Détails fonctionnant exclusivement par effet Peltier ou effet Seebeck caractérisés par la structure ou la configuration de la cellule ou du thermocouple constituant le dispositif
H01L 35/34 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
ST VINCENT'S HOSPITAL (MELBOURNE) LIMITED (Australie)
Inventeur(s)
Choong, Peter F.M.
Francis, Sam Lourdesan
Duchi, Serena
Onofrillo, Carmine
Di Bella, Claudia
Gambhir, Sanjeev
Moulton, Simon Edward
Halkias, Christopher
O'Connell, Cathal D.
Reynolds, Nicholas Paul
Wallace, Gordon George
Abrégé
The invention generally relates to cells and compositions comprising same for use in cell therapy, to methods of obtaining same, and to use of same in cell therapy. In one aspect, the invention provides a method for forming a cell composition from a tissue sample, the method comprising: providing a tissue sample comprising cells; contacting the sample with a polymer in binding conditions, said binding conditions being conditions that enable binding of cells in the sample to the polymer, so that said cells are bound to the polymer; culturing the cells bound to the polymer under conditions and for a time that allows the cell number to increase; providing conditions to induce a phase change of the polymer; thereby forming a cell composition from a tissue sample.
A61K 47/24 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p. ex. cyclométhicone ou phospholipides
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
An implantable device and methods for preparing and implanting said device into a subject for use in treating a medical condition when implanted therein is disclosed. The device comprises at least one composite fibre of a hydrophilic polymer and a hydrophobic polymer, wherein at least one of said polymers is loaded with an agent that is active towards treating the medical condition.
D01F 9/04 - Filaments, ou similaires, faits par l’homme, formés d’autres substancesLeur fabricationAppareils spécialement adaptés à la fabrication de filaments de carbone d'alginates
Provided herein are compounds of formula (I) which comprise a cephalosporin antibiotic (present moiety X), bonded to a piperidine diazeniumdiolate (NONOate) or a salt thereof. Also provided are compositions that include a compound described herein and methods for promoting the dispersal of microorganisms from biofilms, inhibiting biofilm formation or development, treating and preventing biofilm-associated diseases and disorders or a Pseudomonas aeruginosa infection in a subject suffering from cystic fibrosis, and killing a biofilm-forming microorganism. (I)
C07D 501/16 - Composés comportant un atome d'azote lié directement en position 7 avec une double liaison entre les positions 2 et 3
A01N 43/90 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant plusieurs hétérocycles déterminants condensés entre eux ou avec un système carbocyclique commun
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/423 - Oxazoles condensés avec des carbocycles
A61K 31/43 - Composés contenant des systèmes cycliques thia-4 aza-1 bicyclo [3.2.0] heptane, c.-à-d. composés contenant un système cyclique de formule , p. ex. pénicillines, pénèmes
A61K 31/431 - Composés contenant des systèmes cycliques thia-4 aza-1 bicyclo [3.2.0] heptane, c.-à-d. composés contenant un système cyclique de formule , p. ex. pénicillines, pénèmes contenant d'autres systèmes hétérocycliques, p. ex. ticarcilline, azlocilline, oxacilline
A61K 31/546 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine contenant d'autres hétérocycles, p. ex. céphalotine
A61L 101/40 - Composés organiques contenant du soufre
A61L 2/23 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances solides, p. ex. des granules, des poudres, des blocs, des comprimés
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
An anti-cancer agent is provided comprising a tumour homing peptide having, or having been modified to present, two cysteine residues, with an arsenic atom between, such that the tumour homing peptide cyclises to give an arsenic-containing anti-cancer agent. This allows for selection of an appropriate tumour homing peptide for treatment of a given cancer whereby the subsequent agent provides for a more targeted delivery of arsenic to the tumour microenvironment.
Australian Nuclear Science and Technology Organisation (Australie)
University of Wollongong (Australie)
Inventeur(s)
Safavi-Naeini, Mitra
Chacon, Andrew Stephen
Abrégé
An irradiation method and system for irradiating a target volume, the method comprising: providing thermal neutron absorbing nuclides (such as in the form of a high neutron cross-section agent) at the target volume; and producing neutrons by irradiating nuclei in or adjacent to the target volume with a beam of particles consisting of any one or more of protons, deuterons, tritons and heavy ions, thereby prompting production of the neutrons through non-elastic collisions between the atoms in the path of the beam (including the target) and the particles. The neutron absorbing nuclides absorb neutrons produced in the non-elastic collisions, thereby producing capture products or fragments that irradiate the target volume.
H05H 13/10 - Accélérateurs comprenant une ou plusieurs sections d'accélération linéaire et des aimants de courbure ou des dispositifs analogues pour faire revenir les particules chargées sur une trajectoire parallèle à la première section d'accélération, p. ex. microtrons
G21K 5/04 - Dispositifs d'irradiation avec des moyens de formation du faisceau
29.
METHODS OF MAKING AND BIOELECTRONIC APPLICATIONS OF METALIZED GRAPHENE FIBERS
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (USA)
UNIVERSITY OF WOLLONGONG (Australie)
Inventeur(s)
Romero-Ortega, Mario
Wallace, Gordon
Gonzalez Gonzalez, Maria
Jalili, Rouhollah Ali
Abrégé
The present disclosure provides methods of making and applying metalized graphene fibers in bioelectronics applications. For example, platinized graphene fibers may be used as an implantable conductive suture for neural and neuro-muscular interfaces in chronic applications. In some embodiments, an implantable electrode includes a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene-fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating.
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (USA)
UNIVERSITY OF WOLLONGONG (Australie)
Inventeur(s)
Romero-Ortega, Mario
Wallace, Gordon
Gonzalez Gonzalez, Maria
Jalili, Rouhollah Ali
Abrégé
The present disclosure provides methods of making and applying metalized graphene fibers in bioelectronics applications. For example, platinized graphene fibers may be used as an implantable conductive suture for neural and neuro-muscular interfaces in chronic applications. In some embodiments, an implantable electrode includes a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene-fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating.
Board of Regents, The University of Texas System (USA)
Inventeur(s)
Romero-Ortega, Mario
Wallace, Gordon
Gonzalez Gonzalez, Maria
Jalili, Rouhollah Ali
Abrégé
The present disclosure provides methods of making and applying metallized graphene fibers in bioelectronics applications. For example, platinized graphene fibers may be used as an implantable conductive suture for neural and neuro-muscular interfaces in chronic applications. In some embodiments, an implantable electrode includes a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene-fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating.
The present disclosure provides a dispersible graphene platelet and a method of making same. The structure of the graphene platelet 10 comprises a base layer 1 of graphene on which at least one discontinuous layer 2, 3, 4 of graphene is stacked, with each layer of graphene above the base layer having a smaller surface area than the layer it is stacked upon. The edges of the base layer and the discontinuous layers stacked upon it are all at least partially functionalised 5, providing a structure with graphene-like properties owing to the base layer and relatively high dispersibility owing to the increased amount of functionalised groups on each platelet. The platelets may be used for a number of applications, for example in the production of electrodes or composite materials.
An implantable device and methods for preparing and implanting said device into a subject for use in treating a medical condition when implanted therein is disclosed. The device comprises at least one coaxial fibre of a hydrophilic polymer and a hydrophobic polymer, wherein at least one of said polymers is loaded with an agent that is active towards treating the medical condition.
A61K 47/30 - Composés macromoléculaires organiques ou inorganiques, p. ex. polyphosphates inorganiques
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
A61K 31/34 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à cinq chaînons avec un oxygène comme seul hétéro-atome d'un cycle, p. ex. isosorbide
A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
Disclosed herein is a composite material comprising a graphene-based material, manganese oxide, and group II metal ions. The graphene based material may be functionalised with an organic moiety comprising an acidic functional group. The composite material may function as a catalyst for electrolysis of water.
B01J 23/02 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe des métaux alcalins ou alcalino-terreux ou du béryllium
An anti-cancer agent is provided comprising a tumour homing peptide having, or having been modified to present, two cysteine residues, with an arsenic atom between, such that the tumour homing peptide cyclises to give an arsenic- containing anti-cancer agent. This allows for selection of an appropriate tumour homing peptide for treatment of a given cancer whereby the subsequent agent provides for a more targeted delivery of arsenic to the tumour microenvironment.
C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
An anti-cancer agent is provided comprising a tumour homing peptide having, or having been modified to present, two cysteine residues, with an arsenic atom between, such that the tumour homing peptide cyclises to give an arsenic- containing anti-cancer agent. This allows for selection of an appropriate tumour homing peptide for treatment of a given cancer whereby the subsequent agent provides for a more targeted delivery of arsenic to the tumour microenvironment.
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
A device and a method for using a device to receive and/or deliver a substance in vivo is disclosed. The device includes a hollow body having a wall that defines an internal volume, wherein the wall comprises at least one opening extending substantially therethrough to facilitate access to the internal volume, and at least one stimuli- responsive membrane mounted to and substantially around an internal surface of the wall to define at least one chamber that is in fluid communication with the at least one opening and is configured to receive and/or deliver a substance via the at least one opening when an external stimulus is applied in proximity to the at least one stimuli-responsive membrane.
A device and method for immobilising a robotic capsule within a body lumen is disclosed. The device comprises a magnetic actuator, and at least one retractable member operably coupled to the magnetic actuator, wherein the magnetic actuator is responsive to an external magnetic field to cause the at least one retractable member to move between a retracted position, in which the at least one retractable member is substantially disengaged from an intraluminal wall of a body lumen, and a deployed position, in which the at least one retractable member is substantially engaged with the intraluminal wall of the body lumen to immobilise the device, and a robotic capsule coupled thereto, at a site specific location therewithin.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (Australie)
UNIVERSITY OF WOLLONGONG (Australie)
Inventeur(s)
Safavi-Naeini, Mitra
Chacon, Andrew Stephen
Abrégé
An irradiation method and system for irradiating a target volume, the method comprising: providing thermal neutron absorbing nuclides (such as in the form of a high neutron cross-section agent) at the target volume; and producing neutrons by irradiating nuclei in or adjacent to the target volume with a beam of particles consisting of any one or more of protons, deuterons, tritons and heavy ions, thereby prompting production of the neutrons through non-elastic collisions between the atoms in the path of the beam (including the target) and the particles. The neutron absorbing nuclides absorb neutrons produced in the non-elastic collisions, thereby producing capture products or fragments that irradiate the target volume.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
A61N 5/01 - Dispositifs pour produire le mouvement de la source de radiation pendant la thérapie
G21G 1/04 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p. ex. production d'isotopes radioactifs à l'extérieur des réacteurs nucléaires ou des accélérateurs de particules
40.
DOSIMETRY MONITORING AND MOTION TRACKING OF A GUIDED RADIATION THERAPY SYSTEM
Disclosed is a system for monitoring dosimetry and motion tracking of a guided radiation therapy system. The system includes a phantom configured to be sensed by a tracking system associated with the guided radiation therapy system; and a manipulator to which the phantom is mounted, and which is configured to move the phantom along at least 3 axes and about at least 1 axis. A radiation detector may also be associated with the phantom to sense radiation received from the guided radiation therapy system. A method for dosimetry and motion tracking is also disclosed.
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
G01D 18/00 - Test ou étalonnage des appareils ou des dispositions prévus dans les groupes
B25J 13/08 - Commandes pour manipulateurs au moyens de dispositifs sensibles, p. ex. à la vue ou au toucher
B25J 3/00 - Manipulateurs de type à commande asservie, c.-à-d. manipulateurs dans lesquels l'unité de commande et l'unité commandée exécutent des mouvements correspondants dans l'espace
A method of constructing a railway track comprises preparing existing ground so as to receive a layer thereat. Barrier material is laid over the prepared ground. A plurality of tyres that have a single sidewall removed therefrom are placed in a laid-5 flat arrangement such that a remaining sidewall of each resultant tyre cell lies over and adjacent to the barrier material. The tyre cells are in-filled with a fill material. Railway sleepers are arranged in relation to the in-filled layer of tyre cells. Railway tracks are then laid on the railway sleepers.
The present invention broadly relates to 6-substituted derivatives of hexamethylene amiloride, the preparation thereof, and their use in the treatment of diseases such as cancer.
C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
C07D 405/14 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
C07D 409/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
C07D 413/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p. ex. clozapine, dilazèpe
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
43.
High performance computing for three dimensional proton computed tomography (HPC-pCT)
Board of Trustees of Northern Illinois University (USA)
Fermi Research Alliance, LLC (USA)
University of Wollongong (Australie)
Inventeur(s)
Karonis, Nicholas
Coutrakon, George
Duffin, Kirk
Erdelyi, Bela
Naglich, Kevin
Penfold, Scott
Rubinov, Paul
Rykalin, Victor
Zutshi, Vishnu
Abrégé
A proton computed tomography (pCT) detector system, including two tracking detectors in sequence on a first side of an object to be imaged, two tracking detectors in sequence on an opposite side of the object to be imaged, a calorimeter, and a computer cluster, wherein the tracking detectors include plastic scintillation fibers. All fibers in the detector system are read out by Silicon Photomultipliers (SiPM). A method of imaging an object by emitting protons from a source through two tracking detectors, through and around the object, and through two opposite tracking detectors, detecting energy of the protons with a calorimeter, and imaging the object.
G01N 23/04 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et formant des images des matériaux
G01T 1/29 - Mesure effectuée sur des faisceaux de radiations, p. ex. sur la position ou la section du faisceauMesure de la distribution spatiale de radiations
G01T 1/20 - Mesure de l'intensité de radiation avec des détecteurs à scintillation
A wind energy conversion apparatus including: a support frame; an upper pair of axially spaced rotating members located in an upper portion of the support frame; a lower pair of axially spaced rotating members located in a lower portion of the support frame, the upper and lower pair of axially spaced rotating members being in general vertical alignment; two endless support means, each mounted around the vertically aligned upper and lower rotating members and configured to move in a circulating motion whereby movement of the endless support means rotates the upper and lower rotating members; and, a plurality of aerofoils coupled between the two endless support means wherein each aerofoil is coupled between the two endless supports at opposed ends of the aerofoil at a position equal to, or forward of, the centre of mass of the aerofoil, wherein wind travelling past the plurality of aerofoils produces a translational force upon the aerofoil which in turn causes movement of the two endless support means and thereby rotation of the upper and lower rotating members.
Methods and systems for performing mass spectrometry are provided herein. The method includes ionizing one or more compounds to generate ions, passing the ions into an ion mobility spectrometer, providing ozone, reacting the ions with ozone to produce ozone-induced fragment ions, and performing mass analysis and detection of the ozone-induced fragment ions. The system can comprise an ion source for ionizing one or more compounds to generate ions, an ion mobility spectrometer for receiving and separating the ions, an ozone supply for introducing ozone into the system; a reaction region for reacting the ions with the ozone to produce ozone- induced fragment ions, and a mass spectrometer for performing mass analysis and detection of the ozone-induced fragment ions.
An electrode for a water splitting device, the electrode comprising a gas permeable material, a second material, for example a further gas permeable material, a spacer layer positioned between the gas permeable material and the second material, the spacer layer providing a gas collection layer and a conducting layer. The conducting layer can be provided adjacent to or at least partially within the gas permeable material. The gas collection layer is able to transport gas internally in the electrode. The gas permeable materials can be gas permeable membranes. Also disclosed are electrochemical cells using such an electrode as the cathode and/or anode, and methods for bringing about gas-to- liquid or liquid-to-gas transformations, for example for producing hydrogen.
The applicants' teachings provide in some aspects methods and apparatus for mass spectrometric analysis that identify the location of carbon-carbon double bonds, if any, in an analyte by (1) obtaining the m/z ratio of the intact analyte ions, (2) subjecting these ions to collision-induced dissociation and (3) determining relationships between masses and/or mass- to-charge ratios of the intact analyte ions and the fragments produced by such collision- induced dissociation. The methods and apparatus selectively subject analyte ions to ozone- induced dissociation based on those relationships and determine location(s) of carbon-carbon double bonds, if any, from reaction products of ozone- induced dissociation.
G01N 27/62 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'ionisation des gaz, p. ex. des aérosolsRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant les décharges électriques, p. ex. l'émission cathodique
H01J 49/26 - Spectromètres de masse ou tubes séparateurs de masse
48.
REDUCED GRAPHENE OXIDE AND METHOD OF PRODUCING SAME
There is provided a method of producing reduced (rGO) or partially reduced (prGO) Graphene Oxide films that have improved conductivity. The method is capable of creating highly conducting (-2000 S/cm), flexible, printable, processable reduced graphene oxide materials without the need for harsh chemical treatment or high temperature annealing. In one embodiment, an electrical circuit consisting of reduced graphene oxide tracks may be patterned into a graphene oxide film by printing with a reducing agent, preferably ascorbic acid.
H01B 1/04 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement soit de compositions à base de carbone-silicium, soit de carbone soit de silicium
B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
49.
REGULATION OF NITRIC OXIDE RELEASE AND BIOFILM DEVELOPMENT
The present invention relates generally to methods and compounds for regulation of nitric oxide release in the vicinity of biofilm-forming microorganisms to regulate the programmed cell death in the microorganisms. This thereby promotes the dispersal of microorganisms from biofilms and/or the inhibition of biofilm formation or development. More particularly, the invention relates to the use of compounds to provide spatial and temporal control or nitric oxide release. (see above formula)
C07D 501/24 - Acides acylamino-7 céphalosporaniques ou acylamino-7 céphalosporaniques substitués dans lesquels les radicaux acyle sont dérivés d'acides carboxyliques avec des radicaux hydrocarbonés, substitués par des hétéro-atomes ou par des hétérocycles, liés en position 3
A61K 31/545 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine
A61K 31/546 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine contenant d'autres hétérocycles, p. ex. céphalotine
C07D 501/20 - Acides acylamino-7 céphalosporaniques ou acylamino-7 céphalosporaniques substitués dans lesquels les radicaux acyle sont dérivés d'acides carboxyliques
C07D 503/14 - Composés hétérocycliques contenant des systèmes cycliques oxa-4 aza-1 bicyclo [3.2.0] heptane, c.-à-d. des composés contenant un système cyclique de formule: , p. ex. oxapénicillines, dérivés d'acide clavulaniqueCes systèmes cycliques étant ultérieurement condensés, p. ex. condensés en position 2,3 avec des hétérocycles contenant de l'oxygène, de l'azote ou du soufre avec un atome de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. un radical ester ou nitrile, lié directement en position 2 non substitués en position 6 avec des atomes d'hydrogène, des radicaux hydrocarbonés ou hydrocarbonés substitués, autres qu'un atome de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, liés directement en position 3
50.
LIQUID ASSISTED GRINDING METHOD FOR PRODUCING IMPROVED BATTERY MATERIAL
A lithium based composite material and method of preparation. Including grinding a mixture of a lithium salt, a metal oxide or salt, a phosphate salt and a carbon source in the presence of a liquid to produce a slurry. The liquid helps the grinding and homogeneous mixing and is not consumed as a reagent. Upon removing the liquid the slurry becomes a dried mixture, and after heating the dried mixture becomes a composite, which can be used as a cathode material in a lithium-ion battery. For example, the composite is LiFePO4-Fe2P-C and shows a specific capacity of 167 mAh/g at 0.2C and 146 mAh/g at 5C after 100 cycles, respectively. At high current density the example composite exhibits long-term cycling stability, retaining around 96% of its original discharge capacity beyond 1000 cycles, which can meet requirements of a lithium-ion battery for large-scale power applications.
There is provided a spray pyrolysis method for producing a graphene oxide based composite. The method includes spraying graphene oxide in suspension or solution into a reaction chamber. Simultaneously or separately spraying at least one precursor in suspension or solution into the reaction chamber. Heating the reaction chamber to produce an in situ chemical reaction between the graphene oxide and the at least one precursor, and retrieving a graphene oxide based composite from the reaction chamber. GO-Mn2O3/Mn3O4 composites were synthesized using the spray pyrolysis method. The results show unique morphology, afforded by the modified spray solution used including a hydroxide suspension, and enhanced capacitance. An exceptionally high capacitance value of about 606 Fg-1 at 5 mVs-1 was observed for an example 20% GO-Mn2O3/Mn3O4 material.
Regulation of nitric oxide release and biofilm development Abstract The present invention relates generally to methods and compounds for regulating the release of nitric oxide in the vicinity of biofilm-forming microorganisms to regulate programmed cell death in the microorganisms and thereby promote dispersal of microorganism from biofilms and/or inhibit biofilm formation or development. More particularly, the invention relates to the use of compounds to provide spatial and temporal control over nitric oxide release.
C07D 501/24 - Acides acylamino-7 céphalosporaniques ou acylamino-7 céphalosporaniques substitués dans lesquels les radicaux acyle sont dérivés d'acides carboxyliques avec des radicaux hydrocarbonés, substitués par des hétéro-atomes ou par des hétérocycles, liés en position 3
C07D 501/20 - Acides acylamino-7 céphalosporaniques ou acylamino-7 céphalosporaniques substitués dans lesquels les radicaux acyle sont dérivés d'acides carboxyliques
C07D 503/14 - Composés hétérocycliques contenant des systèmes cycliques oxa-4 aza-1 bicyclo [3.2.0] heptane, c.-à-d. des composés contenant un système cyclique de formule: , p. ex. oxapénicillines, dérivés d'acide clavulaniqueCes systèmes cycliques étant ultérieurement condensés, p. ex. condensés en position 2,3 avec des hétérocycles contenant de l'oxygène, de l'azote ou du soufre avec un atome de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. un radical ester ou nitrile, lié directement en position 2 non substitués en position 6 avec des atomes d'hydrogène, des radicaux hydrocarbonés ou hydrocarbonés substitués, autres qu'un atome de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, liés directement en position 3
A61K 31/545 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine
A61K 31/546 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine contenant d'autres hétérocycles, p. ex. céphalotine
In one form, a photoelectrochemical cell comprising a p-type sensitized photocathode including a sensitizer dye and a water-based electrolyte. In another form, the sensitizer dye and an adjacent semiconductor may have a reduction potential that is sufficiently high to either reduce a desired chemical feedstock in the cell or reduce protons in the water to hydrogen gas. The semiconductor to which the sensitizer dye is affixed may be nickel oxide. The photoelectrochemical cell can include a sensitized photocathode and an electrolyte that contains an electron acceptor, where light illumination of the sensitized photocathode results in reduction of the electron acceptor. The electrolyte can include water.
A light-modulating electrical device is disclosed and a method for manufacturing a light-modulating electrical device. The method includes, as a single lamination process, positioning a light-modulating electrical unit at least partially within a recess, the recess provided in a first polymer film or an optically transparent polymer film, and fixing the optically transparent polymer film to the first polymer film so as to cover the light-modulating electrical unit. In one example, the light-modulating electrical unit is comprised of two or more sub-units and is itself formed as part of the lamination process.
B32B 27/06 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique
B32B 15/08 - Produits stratifiés composés essentiellement de métal comprenant un métal comme seul composant ou comme composant principal d'une couche adjacente à une autre couche d'une substance spécifique de résine synthétique
G02F 1/161 - JointsÉléments d’espacementScellement de cellulesRemplissage ou fermeture de cellules
Water-splitting devices and methods for manufacturing water-splitting devices or solar cells is disclosed. The method seeks to provide a relatively high-volume, low-cost mass-production method. In one example, the method facilitates simultaneous co-assembly of one or more sub-units and two or more polymer films or sheets to form a water-splitting device. According to another aspect, there is provided an improved water-splitting device. In one example form, there is provided a water-splitting device which includes a first electrode for producing oxygen gas and a second electrode for producing hydrogen gas from water. The first electrode and the second electrode are positioned between a first outer polymer layer and a second outer polymer layer, and at least one spacer layer is positioned between the first outer polymer layer and the second outer polymer layer.
C25B 9/00 - Cellules ou assemblages de cellulesÉléments de structure des cellulesAssemblages d'éléments de structure, p. ex. assemblages d'électrode-diaphragmeCaractéristiques des cellules relatives aux procédés
H01L 31/042 - Modules PV ou matrices de cellules PV individuelles
A radiation detector is disclosed that comprises a scintillator that emits electromagnetic radiation in response to excitation by radiation of interest, and a photodetector with a semiconductor active layer adapted to interact with the electromagnetic radiation and a substrate. Either the scintillator constitutes the substrate or the substrate is located such that the substrate is between said active layer and the scintillator, and the substrate is at least partially transparent to the electromagnetic radiation.
A proton computed tomography (pCT) detector system, including two tracking detectors in sequence on a first side of an object to be imaged, two tracking detectors in sequence on an opposite side of the object to be imaged, a calorimeter, and a computer cluster, wherein the tracking detectors include plastic scintillation fibers. All fibers in the detector system are read out by Silicon Photomultipliers (SiPM). A method of imaging an object by emitting protons from a source through two tracking detectors, through and around the object, and through two opposite tracking detectors, detecting energy of the protons with a calorimeter, and imaging the object.
Disclosed are systems, devices and methodologies relating to proton computed tomography. In some implementations, detection of protons can yield track information before and after an object for each proton so as to allow determination of a likely path of each proton within the object. Further, measurement of energy loss experienced by each proton allows determination that a given likely path results in a given energy loss. A collection of such data allows characterization of the object. In the context of energy loss, such a characterization can include an image map of relative stopping power of the object. Various reconstruction methodologies for obtaining such an image, including but not limited to superiorization of a merit function such as total variation, are disclosed. In some implementations, various forms of total variation superiorization methodology can yield excellent results while being computationally efficient and with reduced computing time.
The present invention relates to a two-part curable composition, methods for preparing the two-part curable composition and its use as a polymeric material for lining and reinforcement. The two-part curable composition comprises a first part which is a prepolymer composition comprising an unsaturated polyester, a vinyl-functional monomer and an accelerator; and a second part which is a promoter composition comprising a promoter and a vinyl-functional monomer. In use, the promoter composition of the second part promotes curing of the curable composition when the first and second parts are combined.
C08F 283/01 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères prévus par la sous-classe sur des polyesters non saturés
A probe (14; 14'), comprising an ultrasonic probe (56a, 56b; 74a, 74b) and a pixellated radiation detector (16) with discrete detecting elements (50a, 50b, 50c) for detecting a predefined radiation. The probe (14) is adapted to be located at least partially within a body cavity. Also, an imaging method, comprising employing such a probe (14) to form an image while located within a body cavity, and a dosimetry method, comprising employing such a probe (14) to conduct dosimetry while located within a body cavity.
A method of providing cognitive training to a user, the method including, in a processing system, presenting a cognitive task to a user, the cognitive task requiring the user to view presented information and provide at least one input response; determining the at least one input response using an input device; determining from a measuring device a measure of electrical activity in the user's brain whilst performing the cognitive task; and, determining a score based on at least one of the at least one input response and the measured electrical activity.
An encapsulation and compression sports bra (1) with cups (7) formed of elastic material to elevate and compress breasts (8) of a wearer (2) to restrict anatomical breast support structures reaching their end of range during downward breast trajectory to thereby reduce exercise induced breast discomfort.
A42C 3/00 - Appareils pour la fabrication des chapeaux non prévus dans le groupe , p. ex. pour faire des formes en fils métalliques pour armatures de chapeauxAppareils pour modifier la forme ou la taille des chapeaux terminés
A dye composition for use in a photoelectric material, the dye composition comprising a plurality of dyes comprising a chromophore and at least one binding group for binding with a semiconductor (preferably a metal oxide semiconductor) wherein the plurality of dyes include a first dye wherein the binding group is linked to the dye chromophore by a linker not in conjugation with the chromophore and a second dye wherein the binding group is attached by a linker in conjugation with the chromophore.
H01L 31/0256 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par les matériaux
A microdosimeter, comprising an array of three-dimensional p-n junction semiconductor detectors, each providing a sensitive volume-target and a tissue equivalent medium for generating secondary charged particles. The array is manufactured from a semiconductor on insulator wafer and the detectors are located to detect secondary charged particles generated in the tissue equivalent medium.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Paper, cardboard and goods made from these materials, not
included in other classes; printed matter including
newspapers, magazines, periodicals, journals, pamphlets,
books; photographs; promotional displays being banners of
paper, posters and flags of paper; stationery; instructional
and teaching materials; teaching manuals; teaching materials
for education; educational materials (other than apparatus)
for use in teaching. Advertising and promotional services, including the
advertising of educational and training courses and research
services; business administration, consultancy and
management services; business research; compilation of
information; analysis of market research data. Academies (education); academy education services; adult
education; advisory services relating to education and
training; arranging of exhibitions for educational and
training purposes; arranging and conducting of workshops
(training); conducting of educational conferences, courses;
conducting of exhibitions for educational and training
purposes; conducting training seminars and workshops;
consultancy services relating to education and training;
development of educational courses, examinations and
qualifications; dissemination of educational material;
education and training information; education and training
services; educational advisory, assessment, examination,
instruction and research services; educational institute
services; educational seminars; health education;
information services relating to education; international
student exchange programmes; library services; management of
education services and events; mentoring (education and
training); organisation of training courses; practical
training (demonstration); providing facilities for
educational purposes; providing information, including
online, about education, training, entertainment, sporting
and cultural activities; provision of educational courses;
provision of facilities for education; provision of
training; provision of training facilities; provision of
education services via an online forum; publication of
educational texts and materials; setting of educational
standards; sports education and training services; training;
vocational guidance (education or training advice);
vocational education and training services; university
education services. Advisory services relating to research; computer and
software programming services; laboratory research;
laboratory services (scientific research or analysis);
management of scientific research projects; medical research
including scientific research for medical purposes;
preparation of reports and information relating to
scientific and technical research; preparation of statistics
for scientific research; providing information, including
online, about industrial analysis and research services;
research and development (for others); research in all
fields of science and industry, including biology,
biotechnology, design, engineering, medicine, safety and
technology; research services; research, engineering and
technical consultancy for industry; scientific, technical,
engineering, technical data and computer analysis services;
social science research services.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Paper, cardboard and goods made from these materials, not
included in other classes; printed matter including
newspapers, magazines, periodicals, journals, pamphlets,
books; photographs; promotional displays being banners of
paper, posters and flags of paper; stationery; instructional
and teaching materials; teaching manuals; teaching materials
for education; educational materials (other than apparatus)
for use in teaching. Advertising and promotional services, including the
advertising of educational and training courses and research
services; business administration, consultancy and
management services; business research; compilation of
information; analysis of market research data. Academies (education); academy education services; adult
education; advisory services relating to education and
training; arranging of exhibitions for educational and
training purposes; arranging and conducting of workshops
(training); conducting of educational conferences, courses;
conducting of exhibitions for educational and training
purposes; conducting training seminars and workshops;
consultancy services relating to education and training;
development of educational courses, examinations and
qualifications; dissemination of educational material;
education and training information; education and training
services; educational advisory, assessment, examination,
instruction and research services; educational institute
services; educational seminars; health education;
information services relating to education; international
student exchange programmes; library services; management of
education services and events; mentoring (education and
training); organisation of training courses; practical
training (demonstration); providing facilities for
educational purposes; providing information, including
online, about education, training, entertainment, sporting
and cultural activities; provision of educational courses;
provision of facilities for education; provision of
training; provision of training facilities; provision of
education services via an online forum; publication of
educational texts and materials; setting of educational
standards; sports education and training services; training;
vocational guidance (education or training advice);
vocational education and training services; university
education services. Advisory services relating to research; computer and
software programming services; laboratory research;
laboratory services (scientific research or analysis);
management of scientific research projects; medical research
including scientific research for medical purposes;
preparation of reports and information relating to
scientific and technical research; preparation of statistics
for scientific research; providing information, including
online, about industrial analysis and research services;
research and development (for others); research in all
fields of science and industry, including biology,
biotechnology, design, engineering, medicine, safety and
technology; research services; research, engineering and
technical consultancy for industry; scientific, technical,
engineering, technical data and computer analysis services;
social science research services.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Paper, cardboard and goods made from these materials, not
included in other classes; printed matter including
newspapers, magazines, periodicals, journals, pamphlets,
books; photographs; promotional displays being banners of
paper, posters and flags of paper; stationery; instructional
and teaching materials; teaching manuals; teaching materials
for education; educational materials (other than apparatus)
for use in teaching. Advertising and promotional services, including the
advertising of educational and training courses and research
services; business administration, consultancy and
management services; business research; compilation of
information; analysis of market research data. Academies (education); academy education services; adult
education; advisory services relating to education and
training; arranging of exhibitions for educational and
training purposes; arranging and conducting of workshops
(training); conducting of educational conferences, courses;
conducting of exhibitions for educational and training
purposes; conducting training seminars and workshops;
consultancy services relating to education and training;
development of educational courses, examinations and
qualifications; dissemination of educational material;
education and training information; education and training
services; educational advisory, assessment, examination,
instruction and research services; educational institute
services; educational seminars; health education;
information services relating to education; international
student exchange programmes; library services; management of
education services and events; mentoring (education and
training); organisation of training courses; practical
training (demonstration); providing facilities for
educational purposes; providing information, including
online, about education, training, entertainment, sporting
and cultural activities; provision of educational courses;
provision of facilities for education; provision of
training; provision of training facilities; provision of
education services via an online forum; publication of
educational texts and materials; setting of educational
standards; sports education and training services; training;
vocational guidance (education or training advice);
vocational education and training services; university
education services. Advisory services relating to research; computer and
software programming services; laboratory research;
laboratory services (scientific research or analysis);
management of scientific research projects; medical research
including scientific research for medical purposes;
preparation of reports and information relating to
scientific and technical research; preparation of statistics
for scientific research; providing information, including
online, about industrial analysis and research services;
research and development (for others); research in all
fields of science and industry, including biology,
biotechnology, design, engineering, medicine, safety and
technology; research services; research, engineering and
technical consultancy for industry; scientific, technical,
engineering, technical data and computer analysis services;
social science research services.
The present invention relates to a prepolymer composition comprising a polyester prepolymer, a vinyl-functional monomer having a vapour pressure which is less than styrene at 20° C and an accelerator. The prepolymer composition can be combined with a promoter which causes the prepolymer composition to cure. The cured composition forms a polymeric material which is capable of reinforcing surfaces, in particular the surfaces of mine tunnels including longwall coal mine roadways.
C08F 283/01 - Composés macromoléculaires obtenus par polymérisation de monomères sur des polymères prévus par la sous-classe sur des polyesters non saturés
C09D 167/07 - Polyesters non saturés comportant des insaturations carbone-carbone comportant des liaisons non saturées carbone-carbone terminales
69.
PROCESSES FOR PRODUCING ELECTROCHROMIC SUBSTRATES AND ELECTROCHROMIC ARTICLES MADE THEREFROM
The present invention provides a process for producing an electroactive substrate. The process includes providing a substrate having an oxidant layer on a surface thereof, exposing the surface containing the oxidant layer to a vapour containing an aryl or heteroaryl monomer that is polymerizable to form an electroactive polymer, and polymerizing the aryl or heteroaryl monomer in the presence of a volatile Lewis base to form a polyaryl or polyheteroaryl electroactive polymer film on the surface of the substrate. The invention also provides electroactive substrates formed by the process.
C08F 134/04 - Homopolymères de composés cycliques ne contenant pas de radicaux aliphatiques non saturés dans une chaîne latérale et contenant une ou plusieurs liaisons doubles carbone-carbone dans un hétérocycle dans un cycle contenant du soufre
G02F 1/15 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur un effet électrochromique
The present disclosure provides a new type of gapless semiconductor material having electronic properties that can be characterized by an electronic band structure which comprises valence and conduction band portions VB1 and CB1, respectively, for a first electron spin polarisation, and valence and conducting band portions VB2 and CB2, respectively, for a second electron spin polarisation. The valence band portion VB1 has a first energy level and one of CB1 and CB2 have a second energy level that are positioned so that gapless electronic transitions are possible between VB1 and the one of CB1 and CB2, and wherein the gapless semiconductor material is arranged so that an energy bandgap is defined between VB2 and the other one of CB1 and CB2.
H01L 29/66 - Types de dispositifs semi-conducteurs
H01L 49/00 - Dispositifs à l'état solide non couverts par les groupes et et non couverts par une autre sous-classe; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
H01S 3/14 - Lasers, c.-à-d. dispositifs utilisant l'émission stimulée de rayonnement électromagnétique dans la gamme de l’infrarouge, du visible ou de l’ultraviolet caractérisés par le matériau utilisé comme milieu actif
H01L 33/00 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails
H01S 3/102 - Commande de l'intensité, de la fréquence, de la phase, de la polarisation ou de la direction du rayonnement, p. ex. commutation, ouverture de porte, modulation ou démodulation par commande du milieu actif, p. ex. par commande des procédés ou des appareils pour l'excitation
H01S 5/04 - Procédés ou appareils pour l'excitation, p. ex. pompage
This invention relates to a method of forming a multi-layer bonded product. The method involves forming a distribution of fine particles on one or both surfaces of two bodies to be roll-bonded. The particles are selected to be embeddable in the surfaces by forcing the surfaces together. The method further involves arranging the bodies with the two surfaces facing each other so the particles are located between the two surfaces. The method further involves causing a thickness reduction to the two arranged bodies for bonding the surfaces to each other such that the particles are embedded in one or both surfaces, thereby bonding the bodies together.
B21B 45/00 - Dispositifs pour le traitement de surface des pièces spécialement combinés aux laminoirs, disposés dans les laminoirs, ou adaptés pour être utilisés avec les laminoirs
B23K 20/02 - Soudage non électrique par percussion ou par une autre forme de pression, avec ou sans chauffage, p. ex. revêtement ou placage au moyen d'une presse
C23C 8/60 - Diffusion à l'état solide uniquement d'éléments non métalliques dans la couche superficielle de matériaux métalliquesTraitement chimique de surface par réaction entre le matériau métallique de la surface et un gaz réactif, laissant dans le revêtement des produits de la réaction, p. ex. revêtement de conversion, passivation des métaux au moyen de solides, p. ex. de poudres, de pâtes
B21B 47/00 - Agencements, dispositifs ou méthodes auxiliaires, associés au laminage des feuilles de métal multicouches
B23K 20/04 - Soudage non électrique par percussion ou par une autre forme de pression, avec ou sans chauffage, p. ex. revêtement ou placage au moyen d'un laminoir
B22F 7/00 - Fabrication de couches composites, de pièces ou d'objets à base de poudres métalliques, par frittage avec ou sans compactage
B32B 15/00 - Produits stratifiés composés essentiellement de métal
The present invention relates to a process for the preparation of graphene which can be used in the development of graphene paper or films, graphene-based composites and articles for nanoelectronics, nanocomposites, batteries, supercapacitors, hydrogen storage and bioapplications. This process comprises reducing purified exfoliated graphite oxide in the presence of a base.
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
The present invention relates to a method and apparatus for providing additional shielding to a weld site when welding with a consumable self-shielding welding electrode. The method comprises the steps of producing a shroud gas curtain spaced radially outward from the electrode and substantially controlling the axial position of the shroud gas curtain relative to the distal end of the welding electrode during consumption of said electrode during use, wherein the shroud gas curtain comprises a radially outward component of velocity. The present invention also relates to a welding method and apparatus for providing fume extraction in a manual metal arc welding process.
B23K 9/173 - Soudage ou découpage à l'arc utilisant des gaz de protection et une électrode consommable
B23K 9/29 - Dispositifs de support adaptés pour servir de moyens de protection
B23K 31/02 - Procédés relevant de la présente sous-classe, spécialement adaptés à des objets ou des buts particuliers, mais non couverts par un seul des groupes principaux relatifs au brasage ou au soudage
B23K 35/38 - Emploi d'environnements spécifiés, p. ex. d'atmosphères particulières entourant la zone de travail
74.
MULTI-COMPONENT COMPOSITIONS AND METHODS FOR DELIVERY OF ANTI-CANCER AGENTS
The present invention relates to a composition for the treatment or prevention of cancer, the composition comprising 5-fluorouracil, or a pharmaceutically acceptable salt or analogue thereof; folinic acid, or a pharmaceutically acceptable salt thereof, oxaliplatin and a cyclodextrin or a pharmaceutically acceptable salt or derivative thereof.
Isolated proteins and immunogenic fragments thereof, for use in the treatment and prevention of a Group A Streptococcus infection are provided. In particular, the invention provides pharmaceutical compositions and methods of prophylactic and/or therapeutic treatment of a Group A Streptococcus infection.
C07K 14/315 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Streptococcus (G), p. ex. Enterocoques
C07K 4/04 - Peptides ayant jusqu'à 20 amino-acides dans une séquence indéterminée ou partiellement déterminéeLeurs dérivés provenant de bactéries
C07K 16/12 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de bactéries
76.
IMPROVEMENTS IN MAGNESIUM DIBORIDE SUPERCONDUCTING MATERIALS AND METHODS OF SYNTHESIS
Improved magnesium diboride superconducting materials and methods of synthesis are disclosed. Embodiments of the superconducting material comprise at least two starting materials capable of forming MgB2 and at least one dopant compound comprising silicon, carbon, hydrogen and oxygen. The starting materials and the at least one dopant compound are heated and mixed at an atomic level to produce a silicon-doped MgB2 superconducting material. Examples of the dopant compound include silicone oil, Triacetoxy(methyl)silane (2), 1,7-Dichloro-octamethyltetrasiloxane (2) and Tetramethyl orthosilicate (6).
H01L 39/12 - Dispositifs utilisant la supraconductivité ou l'hyperconductivité; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives - Détails caractérisés par le matériau
C04B 35/58 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de non oxydes à base de borures, nitrures ou siliciures
H01L 39/24 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement des dispositifs couverts par ou de leurs parties constitutives
The present invention relates to a method of preparing an intrinsically conducting polymer having a polymeric matrix with an ionic dye retained therein, the method comprising chemical oxidative polymerisation of monomers under acidic conditions in the presence of the ionic dye to form the intrinsically conducting polymer. The invention also relates to a method of forming the intrinsically conducting polymer on a surface of a substrate, a composition for preparing the intrinsically conducting polymer, and to a sensing device comprising the intrinsically conducting polymer.
H01B 1/12 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs composés principalement d'autres substances non métalliques substances organiques
C07D 207/00 - Composés hétérocycliques contenant des cycles à cinq chaînons, non condensés avec d'autres cycles, ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle
H01M 8/00 - Éléments à combustibleLeur fabrication
A method of treating a steel railway wheels to form a required distribution of compressive residual stress in the rim. In general terms the wheel heated and then quenched from the plate towards the rim. The wheel is first heated to form austenite throughout the plate and rim portions. The wheel is then cooled to form bainite/martensite in the plate portion. The wheel is cooled to form bainite/martensite in an inner portion of the rim. The wheel is cooled to form bainite/martensite in an outer portion of the rim.
C21D 9/34 - Traitement thermique, p. ex. recuit, durcissement, trempe ou revenu, adapté à des objets particuliersFours à cet effet pour bandages de rouesTraitement thermique, p. ex. recuit, durcissement, trempe ou revenu, adapté à des objets particuliersFours à cet effet pour jantes
The present invention relates to apparatus and a method for displaying at least one welding condition. The apparatus comprises: a monitoring unit for monitoring at least one welding parameter, a processor for determining at least one welding condition in real-time in response to said monitored parameter(s), and a display operatively associated with said processor for displaying the so-determined welding condition in real-time. The present invention also relates to a method for automatically controlling low fume and/or minimised arc length welding conditions during welding, and a method for automatically controlling welding to avoid globular mode of metal transfer.
B23K 37/00 - Dispositifs ou procédés auxiliaires non spécialement adaptés à un procédé couvert par un seul des autres groupes principaux de la présente sous-classe
The present invention relates to a method of detecting and/or quantifying a target molecule from a sample obtained from a subject wherein the method comprises: (i) incubating a fusion protein or conjugate comprising a Ter binding polypeptide fused to at least one anti-target molecule or fragment thereof with a partially double-stranded oligonucleotide for a time and under conditions sufficient to bind to said Ter binding polypeptide thereby producing a complex; (ii) incubating said complex in the presence of said sample comprising said target molecule for a time and under conditions sufficient for said anti-target molecule to bind to said target molecule thereby producing a target-bound complex; (iii) incubating said target-bound complex in the presence of at least one immobilised molecule wherein said immobilised molecule has an affinity to said target molecule; (iv) incubating said immobilised molecule for a time and under conditions sufficient to bind to said target molecule thus immobilising said target molecule; and (v) detecting and/or quantifying said target molecule.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
A semiconductor radiation sensor (100), comprising a substrate (102), a carrier material (104) mounted to the substrate (102), and a semiconductor detector (106) mounted to the carrier material (104). A radiation sensitive portion of the semiconductor detector (106) is oriented towards the carrier material (104) and generally away from the substrate (102), and the carrier material is adapted to transmit radiation to the radiation sensitive portion of the semiconductor detector (106). A dosimeter comprising the radiation sensor (100) and a method of manufacturing the radiation sensor (100) are also provided.
The present invention relates to compositions comprising 5-fluorouracil, or a pharmaceutically acceptable salt or analogue thereof, folinic acid, or a pharmaceutically acceptable salt thereof and a cyclodextrin, or a pharmaceutically acceptable salt or derivative thereof. The invention also relates to methods for the treatment of cancer using such compositions.
A flow analysis apparatus is disclosed. The flow analysis apparatus has at least one wicking channel fluidically coupled to an absorbent pump. A wicking valve is fluidically coupled to the wicking channel to provide a fluidic connection to the sample source where opening the wicking valve allows the absorbent pump to cause liquid to flow down the wicking channel toward the absorbent pump. Other similar wicking valves can be added to provide functions such as calibration and reagent addition. A detection unit allows for analysis of the liquid as it flows down the wicking channel.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
A radiation detection apparatus and method, the apparatus (100) comprising a first scintillator (112) for interacting with radiation and outputting light in response thereto, a first photodetector (102) adjacent to the first scintillator (112) for receiving and detecting light from the first scintillator (112) and outputting (108) a first output signal in response thereto, a second scintillator (114) located around the first scintillator (112), for interacting with radiation and outputting light in response thereto, and a second photodetector (104) adjacent to the second scintillator (114) for receiving and detecting light from the second scintillator (114) and outputting (110) a second output signal in response thereto.
A microdosimeter, comprising an array of three-dimensional p-n junction semiconductor detectors, each providing a sensitive volume-target and a tissue equivalent medium for generating secondary charged particles. The array is manufactured from a semiconductor on insulator wafer and the detectors are located to detect secondary charged particles generated in the tissue equivalent medium.
The invention relates to compounds comprising a cytotoxic isatin derivative conjugated to a cell targeting moiety via a spacer group. These conjugates allow the cytotoxic isatin derivaties to be targeted to particular cell and tissue types. The invention also relates to novel isatin derivatives, intermediates used in preparing the conjugates and method of using the conjugates.
The present invention relates to nanostructured composites comprising a nanotube network which is at least partially embedded within a carbon layer. The present invention particularly relates to conducting nanostructured composites for use in the fields of energy conversion, energy storage and also the biomedical field. The present invention also relates to a process via CVD of carbon onto a catalyst layer on a substrate.
B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
H01G 9/042 - Électrodes caractérisées par le matériau
The present invention relates to a torch (1) for welding and a method of extracting fume gas from a welding site (8). The torch (1) comprises a high energy beam (2) adapted to provide heat to a welding site (8), and at least one shroud gas port (17) spaced radially outward from the high energy beam (2) and adapted to impart to an exiting shroud gas (16) a radially outward component of velocity. Fume gas is preferably extracted from a position radially intermediate the high energy beam (2) and the shroud gas curtain (16).
B23K 26/14 - Travail par rayon laser, p. ex. soudage, découpage ou perçage en utilisant un écoulement de fluide, p. ex. un jet de gaz, associé au faisceau laserBuses à cet effet
B23K 26/16 - Enlèvement de résidus, p. ex. des particules ou des vapeurs produites pendant le traitement de la pièce à travailler
89.
A SELF-MAINTAINED SENSOR USING A LOW POWER ACTUATOR
A self-maintained chemical sensing system is disclosed. According to the devices and methods of the invention, it is shown that the BCG-based colorimetric sensor could be reproducibly moved between the predefined site to accomplish the self-maintaining and colorimetric measurement. Colorimetric measurements are achieved by analyzing RGB changes using a video camera or by monitoring photocurrent using an LED emitter and LED detector. The calculated energy consumption rate was ~ 0.17 J / cm2 per cycle for a self-maintained and/or autonomous low cost chemical sensor.
G01N 21/13 - Transport des cuvettes ou des échantillons solides vers ou à partir de l'emplacement de recherche
G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
B81B 3/00 - Dispositifs comportant des éléments flexibles ou déformables, p. ex. comportant des membranes ou des lamelles élastiques
The present invention provides an electrically conducting polymeric nanocomposite comprising a first electrically conducting polymer and a second electrically conducting polymer which acts as a dopant of the first electrically conducting polymer. The present invention also provides a method for preparing the polymeric nanocomposite and its use in optical and electrochemical devices including electrochromic devices. For example, the polymeric nanocomposite may be in the form of a nanodispersion which may be printed using an inkjet printer enabling fabrication of electroactive and electrochromic devices using roll-to-roll processing methods.
C08L 79/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant uniquement de l'azote, avec ou sans oxygène ou carbone, non prévues dans les groupes
C08L 65/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions contenant des dérivés de tels polymères
H01B 1/00 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisésEmploi de matériaux spécifiés comme conducteurs
C08L 101/12 - Compositions contenant des composés macromoléculaires non spécifiés caractérisées par des propriétés physiques, p. ex. anisotropie, viscosité ou conductivité électrique
The present invention relates to nanostructured composites, in particular nanotube/ substrate composites for use in the fields of biomedical materials and devices as well as energy conversion and storage, ion transport and liquid and gas separation. The use of such composites as biomaterials are of particular interest.
B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
92.
SUPERCONDUCTING MATERIALS AND METHODS OF SYNTHESIS
Superconducting materials and methods of synthesizing the superconducting materials are disclosed. Embodiments of the methods include mixing at least two starting materials capable of forming a MgB2 superconducting material with at least one organic dopant compound, the organic dopant compound comprising carbon, hydrogen and oxygen. The method further includes shaping the mixed materials into a desired shape and heating the mixed materials to produce a carbon-doped MgB2 super-conducting material.
H01L 39/12 - Dispositifs utilisant la supraconductivité ou l'hyperconductivité; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives - Détails caractérisés par le matériau
H01B 12/04 - Conducteurs, câbles ou lignes de transmission supraconducteurs ou hyperconducteurs caractérisés par leurs formes à fil unique
C04B 35/58 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de non oxydes à base de borures, nitrures ou siliciures
H01L 39/24 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement des dispositifs couverts par ou de leurs parties constitutives
93.
REINFORCED STRUCTURAL CONCRETE MEMBERS AND METHODS CONCERNING SAME
A method for determining the helical pitch (S) of a helical reinforcement member required to provide a helically reinforced concrete beam with a predetermined displacement ductility (&mgr;d), the method including determining the helical pitch (S) using the relationship wherein the displacement ductility (&mgr;d) of the reinforced concrete beam is inversely proportional to the helical pitch (S) of the reinforcement member.
E04C 3/34 - ColonnesPiliersArcs-boutants en béton ou autre matériau analogue à la pierre, avec ou sans éléments de coffrage permanents, avec ou sans armature interne ou externe, p. ex. recouvrements métalliques
E04C 5/01 - Éléments d'armature en métal, p. ex. avec des revêtements rapportés
E04C 5/06 - Éléments d'armature en métal, p. ex. avec des revêtements rapportés de haute résistance à la flexion, c.-à-d. s'étendant essentiellement dans trois dimensions, p. ex. poutres en treillis
A content based image retrieval system that extracts images from a database of images by constructing a query set of features and displaying images that have a minimum dissimilarity metric from images in the database. The dissimilarity metric is a weighted summation of distances between features in the query set and features of the images in the database. The method is useful for image searching such as web-based image retrieval and facial recognition.
A sensor comprises a substrate having nanoparticles of a conducting polymer such as polyanaline printed thereon. Also described is a printing composition for printing onto a substrate, the composition comprising nanoparticles of a conducting polymer such as polyanaline.
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/84 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des composés inorganiques ou le pH
The present invention relates to arc welding torch and a method of extracting fume gas from a welding site. The torch comprises a metal electrode and at least one shield gas port adapted to direct a shield gas curtain around the metal electrode and a welding site. At least one shroud gas port is spaced radially outward from the shield gas port and adapted to impart to an exiting shroud gas a radially outward component of velocity. Fume gas is preferably extracted from a position radially intermediate the shield gas curtain and the shroud gas curtain.
B23K 9/173 - Soudage ou découpage à l'arc utilisant des gaz de protection et une électrode consommable
B23K 35/22 - Baguettes, électrodes, matériaux ou environnements utilisés pour le brasage, le soudage ou le découpage caractérisés par la composition ou la nature du matériau
B23K 35/368 - Emploi de compositions non métalliques spécifiées pour fil fourré, soit seules, soit liées à l'emploi de matériaux spécifiés pour le brasage ou le soudage
B23K 35/38 - Emploi d'environnements spécifiés, p. ex. d'atmosphères particulières entourant la zone de travail
A self powered sensing device (100) comprising: a first electrode (110) comprising a conducting polymer; a second electrode (120); and an electrolyte (130), the self-powered sensing device configured such that said first and second electrodes (110, 120) and said electrolyte (130) operate as an electrochemical cell following an occurrence of a condition to be sensed and at least the first electrode functions as the sensing indicator.
G01N 27/26 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant des variables électrochimiquesRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en utilisant l'électrolyse ou l'électrophorèse
G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
G01N 27/28 - Composants de cellules électrolytiques
The present invention relates to biocompatible composites, in particular biocompatible nanotube composites in the form of a fibre mat and/or film structure, comprising nanotubes and at least one biomolecule. The invention also relates to a process for preparing a biocompatible composite involving (i) forming a dispersing media comprising nanotubes and at least one biomolecule; and either (ii) introducing the dispersing media of step (i) into a coagulating media optionally comprising at least one biomolecule so as to form a continuous fibre; or (iii) filtering the dispersing media of step (i). Alternatively, the process involves (i) forming a dispersing media comprising nanotubes; and (ii) introducing the dispersing media of step (i) into a coagulating media comprising at least one biomolecule so as to form a continuous fibre. The biocompatible composite is useful as a medical device, preferably in a bio-electrode, bio-fuel cell or substrates for electronically stimulated bio-growth.
A61L 27/40 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
C08L 3/00 - Compositions contenant de l'amidon, de l'amylose ou de l'amylopectine ou leurs dérivés ou leurs produits de dégradation
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
C08L 5/00 - Compositions contenant des polysaccharides ou leurs dérivés non prévus dans les groupes ou
A61L 29/12 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
C08K 13/04 - Ingrédients caractérisés par leur forme et ingrédients organiques ou inorganiques
H01B 1/20 - Matériau conducteur dispersé dans un matériau organique non conducteur
A61L 31/12 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent
C08L 1/00 - Compositions contenant de la cellulose, de la cellulose modifiée ou des dérivés de la cellulose
A reinforced concrete beam having a compression region, a helical reinforcement disposed within the compression region, the helical reinforcement having a helix diameter dh, a confined concrete core diameter dc and a helical pitch sh wherein said helical pitch is about 70% or less than the confined concrete core diameter of the helical reinforcement and the minimum helical pitch is about 25mm.
E04C 3/34 - ColonnesPiliersArcs-boutants en béton ou autre matériau analogue à la pierre, avec ou sans éléments de coffrage permanents, avec ou sans armature interne ou externe, p. ex. recouvrements métalliques
E04C 5/01 - Éléments d'armature en métal, p. ex. avec des revêtements rapportés
E04C 5/06 - Éléments d'armature en métal, p. ex. avec des revêtements rapportés de haute résistance à la flexion, c.-à-d. s'étendant essentiellement dans trois dimensions, p. ex. poutres en treillis
SCHEFENACKER VISION SYSTEMS AUSTRALIA PTY LTD (Australie)
UNIVERSITY OF WOLLONGONG (Australie)
Inventeur(s)
Mazurkiewicz, Jakub, Henryk
Wallace, Gordon, George
Innis, Charles, Peter
Edwards, Scott, A.
Murphy, Peter, J.
Hall, Colin
Fabretto, Rick
Abrégé
An electrochromic assembly (32) is disclosed. The assembly comprises: first and second electrodes (22, 24), at least one electrode being transparent; a porous membrane (10) defining a plurality of pores, the membrane having a first refractive index and located between the electrodes (22, 24); an electrolyte filling the pores, the electrolyte having a second refractive index substantially matching the first refractive index, the electrolyte and membrane together forming a substantially transparent electrolytic layer; and at least one electrochromic layer (18) covering at part of the first electrode (22). The membrane 10 is flexible and the spacing between the electrodes (22, 24) is held substantially constant by the membrane (10). The membrane is sealed with sealant (42).
