Disclosed herein are system, method, and computer-readable medium aspects for removing and detecting pacing artifacts from electrocardiogram and cardiac electrogram signals. An aspect includes a circuit board. The circuit board comprises two signal paths configured to receive a signal comprising cardiac data, pacing data, and background electrical noise. The first path comprises a first filter configured to amplify the cardiac data of the signal and suppress the pacing data of the signal. The second path comprises a second filter configured to amplify the pacing data of the signal and suppress the cardiac data of the signal. The circuit board also comprises a thresholding generator configured to establish a threshold amplitude value. The circuit board further comprises a thresholding module configured to apply the threshold amplitude value to the signal, thereby removing parts of amplitude of the signal that are less than or equal to the threshold amplitude value.
Disclosed herein are system and method aspects for monitoring changes in a negative component of a unipolar electrogram. The system can include a memory and at least one processor coupled to the memory. The at least one processor can be configured to receive a unipolar electrogram signal from a catheter, display on at least one digital display a signal waveform based on the unipolar electrogram signal using a first attribute. The signal waveform can represent one or more cycles from a patient's heart. The at least one processor can also be configured to monitor the signal waveform to detect a change in a negative component of the unipolar electrogram signal and to signal the change on the at least one digital display when the change is detected in at least a threshold number of consecutive cycles.
Disclosed herein are system, method, and computer-readable medium aspects for removing and detecting pacing artifacts from electrocardiogram and cardiac electrogram signals. An aspect includes a circuit board. The circuit board comprises two signal paths configured to receive a signal comprising cardiac data, pacing data, and background electrical noise. The first path comprises a first filter configured to amplify the cardiac data of the signal and suppress the pacing data of the signal. The second path comprises a second filter configured to amplify the pacing data of the signal and suppress the cardiac data of the signal. The circuit board also comprises a thresholding generator configured to establish a threshold amplitude value. The circuit board further comprises a thresholding module configured to apply the threshold amplitude value to the signal, thereby removing parts of amplitude of the signal that are less than or equal to the threshold amplitude value.
Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.
Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.
Mayo Foundation for Medical Education and Research (USA)
Inventeur(s)
Drakulic, Budimir S.
Fakhar, Sina
Foxall, Thomas G.
Vlajinic, Branislav
Asirvatham, Samuel J.
Abrégé
Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
Methods, systems, and media are disclosed for detrending a bioelectric signal. In some embodiments, the disclosed system can include a processor configured to receive the bioelectric signal, identify at least one breakpoint section corresponds to a rapid change of amplitude of the bioelectric signal, smooth an amplitude of the bioelectric signal after the at least one breakpoint section; and reconstruct the bioelectric signal based on the smoothed amplitude of the bioelectric signal and a reset of the breakpoint section to remove extrinsic components caused by a non-biological factor from the bioelectric signal
Described herein are embodiments of a switching network for integrating electrophysiology components into an electrophysiology system. These electrophysiology components may include electrophysiology recorder, three-dimensional mapping systems, radio frequency generators, and stimulators. The switching network provides switchable connections, which allow the electrophysiology system to be reconfigured to perform different electrophysiology procedures, such as heart signal recording and mapping, cardiac ablation, or cardiac pacing. A recorder may provide control signals to the switching network to change connections between electrophysiology equipment and a catheter in a patient's heart. The electrophysiology system may control generation of biphasic pulses for use in cardiac pacing. The electrophysiology system may reconfigure the effective size the tip electrode of a split tip catheter.
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
11.
Methods, systems and media for reconstructing bioelectronic lead placement
Methods, systems, and media are disclosed for reconstructing bioelectronic lead placement. In some embodiments, the disclosed system can include a processor configured to determine relationships between EP signals of one or more pairs of a plurality of electrodes over one or more sampling time periods, wherein the plurality electrodes are separately placed on a patient's body for collecting the EP signals, and to reconstruct geometry of the plurality of electrodes based on the relationships between the EP signals.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Medical instruments in the nature of computer hardware and downloadable computer software for transmitting and monitoring electrical pulses for assisting electrophysiologists during electrophysiology research studies, for performing cardiac ablations, and for diagnosis of arrhythmia; Recorded computer software for reviewing and analyzing data, algorithms, and signals in the field of cardiac electrophysiology; Recorded computer software, namely, a software module used in an electrophysiology navigation and ablation system for cardiac electrophysiology Medical instruments for assisting electrophysiologists during electrophysiology cardiac research studies, for performing cardiac ablations, and for diagnosis of arrhythmia; Medical device, apparatus, and instruments for use in sensing, acquiring, digitizing, amplifying, filtering, measuring, calculating, analyzing, diagnosing, displaying, recording, and storing biomedical data, algorithms and signals in the fields of cardiology, neurology, nephrology, cognitive disorders and chronic pain
Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.
G10L 21/0224 - Traitement dans le domaine temporel
H04B 1/10 - Dispositifs associés au récepteur pour limiter ou supprimer le bruit et les interférences
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
A61B 5/308 - Circuits d’entrée à cet effet spécialement adaptés à des utilisations particulières pour l’électrocardiographie [ECG]
G06F 5/10 - Procédés ou dispositions pour la conversion de données, sans modification de l'ordre ou du contenu des données maniées pour modifier la vitesse de débit des données, c.-à-d. régularisation de la vitesse ayant une séquence d'emplacements d'emmagasinage, chacun étant individuellement accessible à la fois pour des opérations de mise en file d'attente et pour des opérations de retrait de file d'attente, p. ex. utilisant une mémoire à accès aléatoire
Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0245 - Mesure du pouls ou des pulsations cardiaques utilisant des capteurs engendrant des signaux électriques
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
A61B 5/308 - Circuits d’entrée à cet effet spécialement adaptés à des utilisations particulières pour l’électrocardiographie [ECG]
H04L 12/26 - Dispositions de surveillance; Dispositions de test
H04L 12/863 - Ordonnancement de file d’attente, p.ex. ordonnancement circulaire
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
09 - Appareils et instruments scientifiques et électriques
Produits et services
Computer hardware featuring preinstalled signal processing technology software for diagnosing and treating sympathetic nervous system disorders, cardiovascular diseases, nephrological diseases, cognitive disorders, and chronic pain.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Recorded software for reviewing and analyzing data, algorithms, and signals in the field of cardiac electrophysiology; recorded computer software, namely, a software module used in an electrophysiology navigation and ablation system for cardiac electrophysiology.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Recorded software for reviewing and analyzing data, algorithms, and signals in the field of cardiac electrophysiology; recorded computer software, namely, a software module used in an electrophysiology navigation and ablation system for cardiac electrophysiology.
19.
Systems and methods for performing electrophysiology (EP) signal processing
Mayo Foundation for Medical Education and Research (USA)
Inventeur(s)
Drakulic, Budimir S.
Fakhar, Sina
Foxall, Thomas G.
Vlajinic, Branislav
Asirvatham, Samuel J.
Abrégé
Systems, methods, and computer program product embodiments are disclosed for filtering noise from an input signal. An embodiment accesses the input signal having a first harmonic frequency and having the noise. The embodiment determines a quiet period in the input signal. The embodiment stores samples of the noise of the input signal in a buffer during the quiet period. The embodiment subtracts the samples from a single cycle of the noise in the buffer from the input signal to create a filtered signal. The embodiment then repeats the determining, storing, and subtracting to refine the filtered signal.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0245 - Mesure du pouls ou des pulsations cardiaques utilisant des capteurs engendrant des signaux électriques
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
H04L 12/26 - Dispositions de surveillance; Dispositions de test
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0245 - Mesure du pouls ou des pulsations cardiaques utilisant des capteurs engendrant des signaux électriques
A61B 5/318 - Modalités électriques se rapportant au cœur, p. ex. électrocardiographie [ECG]
A61B 5/308 - Circuits d’entrée à cet effet spécialement adaptés à des utilisations particulières pour l’électrocardiographie [ECG]
H04L 12/26 - Dispositions de surveillance; Dispositions de test
H04L 12/863 - Ordonnancement de file d’attente, p.ex. ordonnancement circulaire
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
09 - Appareils et instruments scientifiques et électriques
Produits et services
Computer hardware featuring preinstalled signal processing technology software for diagnosing and treating sympathetic nervous system disorders, cardiovascular diseases, nephrological diseases, cognitive disorders, and chronic pain
22.
Apparatus for processing biomedical signals for display
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/0428 - Circuits d'entrée spécialement adaptés à cet effet
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0456 - Détection des crêtes de l'onde R, p.ex. pour la synchronisation d'appareils de diagnostic
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/0428 - Circuits d'entrée spécialement adaptés à cet effet
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0456 - Détection des crêtes de l'onde R, p.ex. pour la synchronisation d'appareils de diagnostic
Systems, apparatus, and methods are disclosed for processing biomedical signals. An electrophysiology (EP) system includes a differential circuit to process the biomedical signals; a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter and a digital processing stage having a plurality of signal modules; and at least one processor to execute the plurality of signal modules, applying digital signal processing to the output from the analog-to-digital converter, to extract features of interest of the biomedical signals.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
H04L 12/863 - Ordonnancement de file d’attente, p.ex. ordonnancement circulaire
H04L 12/26 - Dispositions de surveillance; Dispositions de test
A61B 5/363 - Détection de la tachycardie ou de la bradycardie
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0538 - Mesure de l'impédance ou de la conductivité électrique d'une partie du corps invasive, p. ex. en utilisant un cathéter
A61B 5/352 - Détection des crêtes de l'onde R, p. ex. pour la synchronisation d'appareils de diagnosticEstimation de l’intervalle entre crêtes R
A61B 5/366 - Détection de complexes QRS anormaux, p. ex. élargissement
25.
Systems and methods for performing electrophysiology (EP) signal processing
Mayo Foundation for Medical Education and Research (USA)
Inventeur(s)
Drakulic, Budimir S.
Fakhar, Sina
Foxall, Thomas G.
Vlajinic, Branislav
Asirvatham, Samuel J.
Abrégé
Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The embodiment further includes a communications interface communicatively coupled to a remote device, and a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface. The processor is configured to receive, via the communications interface, feedback from the remote device. The processor is further configured to control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device.
A61K 31/7105 - Acides ribonucléiques naturels, c.-à-d. contenant uniquement des riboses liés à l'adénine, la guanine, la cytosine ou l'uracile et ayant des liaisons 3'-5' phosphodiester
H04L 12/863 - Ordonnancement de file d’attente, p.ex. ordonnancement circulaire
H04L 12/26 - Dispositions de surveillance; Dispositions de test
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/0428 - Circuits d'entrée spécialement adaptés à cet effet
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0456 - Détection des crêtes de l'onde R, p.ex. pour la synchronisation d'appareils de diagnostic
Mayo Foundation for Medical Education and Research (USA)
Inventeur(s)
Drakulic, Budimir S.
Fakhar, Sina
Foxall, Thomas G.
Vlajinic, Branislav
Asirvatham, Samuel J.
Abrégé
Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
Mayo Foundation for Medical Education and Research (USA)
Inventeur(s)
Drakulic, Budimir S.
Fakhar, Sina
Foxall, Thomas G.
Vlajinic, Branislav
Asirvatham, Samuel J.
Abrégé
Systems, methods, and computer program product embodiments are disclosed for displaying cardiac signals based on a signal pattern. An embodiment operates by accessing an input cardiac signal. The embodiment matches a portion of the input cardiac signal to a known signal pattern. The embodiment then displays an indication of a degree of the match.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
Apparatus, methods, and systems relate to an electrophysiology (EP) recording system for acquisition and preservation of cardiac electrical signals. The EP recording system provides defibrillator protection and radio frequency (RF) ablation signal noise suppression while preserving the integrity of relevant components of raw small signals. The EP recording system has a low-noise amplifier topology with minimal hardware filtering and a high-resolution A/D converter that provides clean, raw digital signals. The raw signals are filtered and processed by the EP system using software-based digital signal processing algorithms that allow the real-time display of signals as a raw signal, or as a combination of raw and processed signals simultaneously, in a single window or in multiple windows. The EP recording system allows for the synchronized display of signals with more than one signal processing algorithm applied at the same time, allowing a user to study signals filtered for specific purposes.
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (USA)
Inventeur(s)
Drakulic, Budimir S.
Fakhar, Sina
Foxall, Thomas G.
Vlajinic, Branislav
Asirvatham, Samuel J.
Abrégé
Systems, methods, and computer program product embodiments are disclosed for displaying signals based on a signal characteristic, such as a late potential or an early activation. An embodiment operates by matching, by a first digital signal processor (DSP) of a first signal module, a beat in a first packet associated with a first cardiac signal to a known signal characteristic. The embodiment also searches, by a second DSP of a second signal module, for the signal characteristic in a second packet associated with a second cardiac signal in response to the matching. The embodiment displays, by a display module coupled to the first signal module and the second signal module, a portion of the first cardiac signal. The embodiment then displays, by the display module, a portion of the second cardiac signal comprising the signal characteristic time-synchronized to the displayed portion of the first cardiac signal based on the searching.
Systems, apparatus, and methods are disclosed for bi-directionally conveying biomedical signals between a patient and signal acquisition and processing devices. An electrophysiology (EP) system includes an analog input protection and filtering stage with a differential circuit to process the biomedical signals to and from the patient; a signal amplification stage with a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter stage to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter stage and a digital processing stage having a plurality of signal modules; at least one processor to execute the plurality of signal modules, applying frequency-selective filtering and signal processing algorithms to the output from the analog-to-digital converter stage, to extract high-frequency and low-amplitude features of the biomedical signals in frequency ranges of interest; and a display for pattern- and time-aligned visualization of the biomedical signals.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
31.
Systems and methods to visually align signals using delay
Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/0428 - Circuits d'entrée spécialement adaptés à cet effet
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0456 - Détection des crêtes de l'onde R, p.ex. pour la synchronisation d'appareils de diagnostic
Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/0428 - Circuits d'entrée spécialement adaptés à cet effet
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0456 - Détection des crêtes de l'onde R, p.ex. pour la synchronisation d'appareils de diagnostic
Systems, apparatus, and methods are disclosed for conveying signals between a patient and monitoring and treatment devices. An EP system provides large-signal input protection and RF ablation signal noise suppression while preserving the integrity of relevant components of small signals. The EP system has a low-noise amplifier topology with minimal hardware filtering. An input protection circuit shunts to ground signals with amplitude above an ablation voltage. An RF filter circuit linearly attenuates the signals between 300 kHz and 600 kHz. A low-frequency feedback circuit drives a common mode node of the RF filter circuit for additional attenuation. A signal amplification circuit amplifies the signals between 0.01 Hz and 1000 Hz. A fast recovery circuit feeds back a low-frequency voltage signal to the signal amplification circuit to gradually reduce offset voltage of the signals. A high-resolution A/D converter converts the signals from the signal amplification circuit to clean digital signals.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/0428 - Circuits d'entrée spécialement adaptés à cet effet
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
H02H 9/04 - Circuits de protection de sécurité pour limiter l'excès de courant ou de tension sans déconnexion sensibles à un excès de tension
H03F 3/68 - Combinaisons d'amplificateurs, p. ex. amplificateurs à plusieurs voies pour stéréophonie
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/0456 - Détection des crêtes de l'onde R, p.ex. pour la synchronisation d'appareils de diagnostic
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Medical instruments in the nature of computer hardware and downloadable computer software for transmitting and monitoring electrical pulses for assisting electrophysiologists during electrophysiology research studies, for performing cardiac ablations, and for diagnosis of arrhythmia Medical instruments for assisting electrophysiologists during electrophysiology cardiac research studies, for performing cardiac ablations, and for diagnosis of arrhythmia; medical device, apparatus, and instruments for use in sensing, acquiring, digitizing, amplifying, filtering, measuring, calculating, analyzing, diagnosing, displaying, recording, and storing biomedical data, algorithms and signals in the fields of cardiology, neurology, nephrology, cognitive disorders and chronic pain
09 - Appareils et instruments scientifiques et électriques
35 - Publicité; Affaires commerciales
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Downloadable podcasts in the field of bioelectronic medicine; electronic publications, namely, books, magazines, articles, and reports featuring information about bioelectronic medicine recorded on computer media Promoting public awareness in the field of bioelectronic medicine; promoting public awareness of bioelectronic medicine by means of public advocacy; providing public policy information in the field of bioelectronic medicine; business research in the field of bioelectronic medicine; promoting collaboration within the scientific, research and medical communities to achieve advances in the field of bioelectronic medicine; business collaboration services, namely, providing a computer-based networking web site for business professionals, academics, and medical professionals to collaborate on, advocate for, and build awareness of bioelectronic medicine Providing a website featuring blogs and non-downloadable publications in the nature of articles, e-books, e-magazines, and reports in the field of bioelectronic medicine; educational services, namely, hosting, arranging, and conducting conferences, seminars, roundtable meetings, webinars in the field of bioelectronic medicine; production of podcasts; entertainment services, namely, providing podcasts in the field of bioelectronic medicine
40.
Systems and methods to visually align signals using delay
Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.
A signal processing evaluator and methods that compare a digital waveform of a cardiac signal to a first processed signal generated by a test system such as an EP recorder or an EP mapping system and generates a first finding evaluating how well the test system filters non-cardiac signals or simulated body impedance. A simulator and methods that send cardiac signals including non-cardiac signals or simulated body impedance to a test system and to a signal processing evaluator for evaluation of the test system.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
A signal processing evaluator and methods that compare a digital waveform of a cardiac signal to a first processed signal generated by a test system such as an EP recorder or an EP mapping system and generates a first finding evaluating how well the test system filters non-cardiac signals or simulated body impedance. A simulator and methods that send cardiac signals including non-cardiac signals or simulated body impedance to a test system and to a signal processing evaluator for evaluation of the test system.
