SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jin Young
Lee, Chan Woo
Lim, Hyun Woo
Park, Jae Hyun
Abrégé
The present disclosure relates to a method for easily preparing niobium-containing titanium-ruthenium composite nanoparticles with excellent stability and electrochemical properties, niobium-containing titanium-ruthenium composite nanoparticles with excellent stability and efficiency, and a chlorine evolution electrode comprising the same.
C25B 11/093 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un métal noble ou oxyde de métal noble et au moins un oxyde d’un métal non noble
C25B 11/037 - Électrodes constituées de particules
2.
NANOCARRIER FOR BIOMATERIAL DELIVERY, NANOCARRIER-BIOMATERIAL COMPLEX, MANUFACTURING METHODS THEREOF AND TREATMENT METHOD FOR LIVING PLANT-BASED OBJECT USING NANOCARRIER
Seoul National University R&DB foundation (République de Corée)
Inventeur(s)
Kwak, Seon Yeong
Seo, Pil Joon
Jeong, Woojin
Jeong, Yeong Yeop
Abrégé
The present disclosure provides a nanocarrier for delivering biomaterials into a living plant-based object including a nanotube, and a functional compound bound to a surface of the nanotubes and including an imidazole, wherein the nanocarrier is configured to deliver a ribonucleic acid (RNA) that promotes a regeneration of plant cells of the object as the biomaterial, into the object.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Sang-Koog
Kim, Bojong
Kim, Junyoung
Jeon, Hae-Chan
Abrégé
A signal transmission control device may include a device layer including a conductive layer and a dielectric layer disposed on the conductive layer, and a conductive line disposed on the dielectric layer and extending across a first inverted split ring resonator (ISRR) and a second inverted split ring resonator (ISRR). The device layer may define the first ISRR and the second ISRR spaced apart from each other, and a signal transmission characteristic between a first end and a second end of the conductive line may be controlled by the first ISRR and the second ISRR.
H01Q 1/38 - Forme structurale pour éléments rayonnants, p. ex. cône, spirale, parapluie formés par une couche conductrice sur un support isolant
H01Q 15/00 - Dispositifs pour la réflexion, la réfraction, la diffraction ou la polarisation des ondes rayonnées par une antenne, p. ex. dispositifs quasi optiques
H04B 17/391 - Modélisation du canal de propagation
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Sangbum
Kang, Donghoon
Yoon, Minsik
Abrégé
A semiconductor device includes a plurality of horizontal electrode layers stacked in a first direction perpendicular to an upper surface of a substrate; a plurality of vertical structures extending in the first direction, penetrating the plurality of horizontal electrode layers and arranged in a second direction and a third direction parallel to the upper surface of the substrate and intersecting each other; and a plurality of bitlines connected to the plurality of vertical structures in the first direction, wherein each of the plurality of vertical structures includes a vertical electrode layer having a pillar shape extending in the first direction, and a phase change material layer extending in the first direction and disposed between the vertical electrode layer and the plurality of horizontal electrode layers in the second direction and the third direction.
H10B 63/10 - Dispositifs RAM à changement de phase [PCRAM, PRAM]
G06N 3/04 - Architecture, p. ex. topologie d'interconnexion
G06N 3/063 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques
5.
SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING ELECTRODE-SEMICONDUCTOR MATERIAL JUNCTION STRUCTURE
Samsung Electronics Co., Ltd. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Ryu, Huije
Lee, Gwanhyoung
Joo, Jaewoong
Abrégé
A semiconductor device may include a channel layer on a substrate and including a semiconductor material, and an electrode layer forming an ohmic-contact with the channel layer. The electrode layer may include a metallic transition metal dichalcogenide (TMD) material in contact with the channel layer.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Oh, Dong-Chan
Lee, Sang Kook
Park, Jiyoon
Moon, Dong Hyun
Abrégé
Provided are a novel oxazolomycin compound, a stereoisomer, solvate, or pharmaceutically acceptable salt thereof, a use thereof, and a production method thereof. The compound has anticancer activity and thus the compound, stereoisomer, solvate, or pharmaceutically acceptable salt thereof can be used for preventing or treating cancer.
C12P 17/16 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle contenant plusieurs hétérocycles
A61K 31/422 - Oxazoles non condensés et contenant d'autres hétérocycles
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Oh, Dong-Chan
Lee, Sang Kook
Du, Young Eun
Bae, Eun Seo
Park, Sooyeon
Abrégé
The present invention relates to a novel thioamide compound, a production method therefor, and uses thereof. The novel thioamide compound, stereoisomers thereof, solvates, or pharmaceutically acceptable salts of the present invention not only exhibit anticancer efficacy against various carcinomas, but also have excellent anticancer activity against anticancer drug-resistant cancers, and thus can be used for the prevention or treatment of various types of cancers.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
INSTITUTE FOR BASIC SCIENCE (République de Corée)
Inventeur(s)
Kim, V. Narry
Baek, Seungchan
Kim, Boseon
Jang, Harim
Abrégé
The present invention relates to a novel modified precursor of an RNA interference-inducing nucleic acid molecule, to a method for designing the modified precursor, and to a method for producing an RNA interference-inducing nucleic acid molecule. A modified precursor, according to one aspect, can be efficiently and homogeneously processed, and thus exhibits a higher expression level in cells, thereby being useful for design and regulation studies of RNA interference-inducing nucleic acid molecules.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
EGC THERAPEUTICS, INC. (République de Corée)
Inventeur(s)
Hwang, Nathaniel Suk-Yeon
Lee, Jaewoo
An, Young-Hyeon
Choee, Jong Hwa
Kim, Beom Seok
Abrégé
The present invention relates to a paintable hydrogel system. The hydrogel system possesses adhesive properties and carries therapeutic factors. According to the present invention, the hydrogel system overcomes limitations such as tissue damage and fibrosis associated with methods for delivering a substance for injection or patch-type treatment, and can be applied without limitation to the shape and size of a target site. In addition, the system can be easily and stably applied in transplantation fields involving synthetic drugs, stem cells, healthcare electronic devices, etc.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61L 33/00 - Traitement antithrombogénique d'articles chirurgicaux, p. ex. de sutures, cathéters, prothèses ou d'articles pour la manipulation ou le conditionnement du sangMatériaux pour un tel traitement
10.
METHOD FOR GENERATING ARTIFICIAL INTELLIGENCE MODEL BY USING NATURAL LANGUAGE INSTRUCTIONS, AND METHOD AND DEVICE FOR DRIVING ROBOT BY USING ARTIFICIAL INTELLIGENCE MODEL
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Zhang, Byoung-Tak
Kim, Junghyun
Abrégé
One embodiment of the present disclosure provides a method for generating an artificial intelligence model by using natural language instructions. The method comprises the steps of: recognizing, from an image, at least one object in the image; extracting features of the object; generating natural language instructions for the object according to preset criteria and requirements on the basis of the features; and generating an artificial intelligence model trained to output control signals of a robot on the basis of a training data set including the image, the features, and the natural language instructions.
G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Ye, Sung-Joon
Lee, Chang-Min
Abrégé
According to the present disclosure, a GPU-based radiation transport computing apparatus includes: an interface module configured to communicate with an external device; a memory configured to store a radiation transport computation program; at least one GPU; and a CPU configured to control the execution of the radiation transport computation program. Herein, the radiation transport computation program allocates, in the GPU, a first buffer for processing source particles, a second buffer for processing information about a transport process of radioactive particles, and a third buffer for processing information about various particles generated in a reaction during radiation exposure, selects a buffer to process a thread block that performs a Monte Carlo algorithm based on occupancy rates of the first to third buffers, and performs sampling on the selected buffer through each thread block according to the Monte Carlo algorithm.
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Park, Namkyoo
Yu, Sunkyu
Yoon, Gyoungsub
Abrégé
A metasurface design apparatus and method are provided. A metasurface design apparatus according to an embodiment of the present invention is a metasurface design apparatus for designing a metasurface that is applied to a seven-tesla (7T) brain magnetic resonance imaging method, the metasurface design apparatus including a memory in which at least one instruction is stored, and a processor configured to execute the at least one instruction stored in the memory, wherein the processor acquires design information about an artificial magnetic field scatterer, acquires a plurality of high-frequency magnetic field (B1+) modes distinguished from each other using the acquired design information, detects an optimal combination of the high-frequency magnetic field modes for homogenizing a high-frequency magnetic field, and designs an optimal metasurface based on the detected optimal combination.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Park, Dong Yoon
Park, Chong Rae
Kim, Jae Ho
Abrégé
The present disclosure relates to a multilayer core-shell structure, a method for producing the same, and a cathode active material for a lithium-sulfur cell including the same. More specifically, the present disclosure provides a multilayer core-shell structure that has reduced defects in the shell and is capable of stably maintaining its structure, and a cathode active material for a lithium-sulfur cell, which is capable of providing a lithium-sulfur cell having excellent rate capability and excellent cycle life characteristics such as long-term stability.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Youngki
Kang, Taeho
Abrégé
Described herein are an apparatus and method for predicting a three-dimensional (3D) pose. The apparatus for predicting a 3D pose includes: an input/output interface configured to receive a plurality of pieces of image data obtained by observing a user's body parts from a first-person viewpoint and output the results of computation processing of the image data; memory configured to store a program for performing a method of predicting a 3D pose; and a controller configured to predict the user's 3D pose based on the image data received through the input/output interface by executing the program. The control unit generates the plurality of pieces of image data as limb heatmaps and joint heatmaps, extracts a joint feature vector, outputs a propagation feature vector by propagating a relational feature vector between neighboring joints, and predicts the user's 3D pose based on the propagation feature vector and the joint feature vector.
G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
15.
ELECTROLYSIS DEVICE FOR HYDROGEN PEROXIDE PRODUCTION AND SIMULTANEOUS CARBON DIOXIDE CAPTURE, AND METHOD FOR HYDROGEN PEROXIDE PRODUCTION AND SIMULTANEOUS CARBON DIOXIDE CAPTURE USING SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Junghun
Lee, Changha
Abrégé
Provided is an electrolysis device for hydrogen peroxide production and carbon dioxide capture according to one aspect. The electrolysis device comprises: a reduction electrode reaction chamber including a reduction electrode; an oxidation electrode reaction chamber including an oxidation electrode; a separation membrane which selectively permeates charges and ionic species between the reduction electrode reaction chamber and the oxidation electrode reaction chamber; an oxygen supply unit for supplying oxygen to the reduction electrode; and a carbon dioxide supply unit for supplying carbon dioxide to the reduction electrode, wherein the reduction electrode is a gas diffusion electrode (GDE) including a hydrophobic carbon catalyst layer.
C25B 9/75 - Assemblages comprenant plusieurs cellules du type filtre-presse avec une électrode bipolaire
C25B 15/08 - Alimentation ou vidange des réactifs ou des électrolytesRégénération des électrolytes
C25B 9/23 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes comprenant des membranes échangeuses d'ions dans ou sur lesquelles est incrusté du matériau pour électrode
C02F 1/46 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques
C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse
16.
METHOD AND APPARATUS FOR GENERATING NATURAL LANGUAGE INSTRUCTION ON BASIS OF VISUAL RECOGNITION
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Zhang, Byoung-Tak
Kim, Junghyun
Abrégé
One embodiment of the present disclosure provides a method for generating a natural language instruction on the basis of visual recognition. This method comprises the steps of: recognizing one or more objects in an image from the image; extracting features of the objects; and generating a natural language instruction for the objects according to pre-configured criteria and requirements on the basis of the features.
G06V 20/70 - Étiquetage du contenu de scène, p. ex. en tirant des représentations syntaxiques ou sémantiques
G06V 10/40 - Extraction de caractéristiques d’images ou de vidéos
G06V 10/75 - Organisation de procédés de l’appariement, p. ex. comparaisons simultanées ou séquentielles des caractéristiques d’images ou de vidéosApproches-approximative-fine, p. ex. approches multi-échellesAppariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques utilisant l’analyse de contexteSélection des dictionnaires
G06V 10/56 - Extraction de caractéristiques d’images ou de vidéos relative à la couleur
G06V 10/54 - Extraction de caractéristiques d’images ou de vidéos relative à la texture
G06V 10/94 - Architectures logicielles ou matérielles spécialement adaptées à la compréhension d’images ou de vidéos
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Park, Tai Hyun
Hong, Seung Hun
Song, Hyun Seok
Jin, Hye Jun
An, Sae Ryun
Abrégé
The present invention relates to a nanovesicle comprising a heterodimeric G-protein coupled receptor, a method for preparing the nanovesicle, a field effect transistor-based taste sensor comprising the nanovesicle, and a method for manufacturing the taste sensor. The field effect transistor based taste sensor functionalized by the nanovesicle comprising the heterodimer G-protein coupled receptor according to the present invention has excellent sensitivity and selectivity and may highly specifically detect a sweet taste substance in real time, by using the heterodimeric G-protein coupled receptor and the nanovesicle comprising the same.
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
G01N 33/74 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des hormones
H10K 10/46 - Transistors à effet de champ, p. ex. transistors organiques à couche mince [OTFT]
H10K 85/00 - Matériaux organiques utilisés dans le corps ou les électrodes des dispositifs couverts par la présente sous-classe
H10K 85/20 - Composés de carbone, p. ex. nanotubes de carbone ou fullerènes
18.
STEREOTYPIC BCR CLONOTYPES IN ALZHEIMER'S DISEASE PATIENTS AND USE THEREOF
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Chung, Junho
Yang, Hyunji
Yoo, Duck Kyun
Han, Ji Won
Kim, Ki Woong
Bae, Jong Bin
Kwon, Sunghoon
Lee, Yonghee
Kim, Namphil
Abrégé
The present specification discloses a composition, a system, and a method for predicting or diagnosing Alzheimer's disease, comprising a detecting agent of a B cell receptor clonotype specific to an Alzheimer's disease patient, and the composition according to one aspect of the present invention has an excellent effect in predicting or diagnosing Alzheimer's disease by simply using peripheral blood mononuclear cells isolated from a subject, in addition to methods such as MRI and PET scans using radioactive substances, by comprising a detecting agent of a B cell receptor (BCR) clonotype specific to an Alzheimer's disease patient.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
Samsung Electronics Co., Ltd. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sooyong
You, Tackgeun
Han, Bohyung
Kim, Bongkeun
Na, Yeojin
Jeong, Seongtae
Abrégé
A vector image generator model training method includes receiving a vector image, transforming a raw image that is the received vector image, and generating an augmented image, and outputting the vector image by using a vector image generator model, based on the raw image and the augmented image. The vector image generator model includes a neural network model, and the vector image generator model is configured to output the raw image when the raw image and the augmented image are input.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Oh, Dong-Chan
Huynh, Thanh-Hau
Lee, Sang Kook
Jang, Sung Chul
Abrégé
The present invention relates to a novel spiro-macrolide compound, a stereoisomer thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof, a method for producing same, and a use thereof. As the compound has anticancer activity, the compound, a stereoisomer thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof may be used for preventing or treating cancer.
C12P 17/18 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle contenant plusieurs hétérocycles condensés entre eux ou condensés avec un système carbocyclique commun, p. ex. rifamycine
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Kihwan
Lee, Hyuk Jae
Jeon, Dongsuk
Nguyen, Xuan Truong
Abrégé
A convolution operation device, according to a first aspect of the present invention, comprises: an input unit that receives input data; a constant generation circuit that generates a plurality of constants and includes at least one node corresponding to each of the plurality of constants, and a multiplexer that, according to an applied signal, supplies either an input value or the result of computation performed on the input value by a computation element to a subsequent computation element; a memory that can store computer-executable instructions; and a processor that, by executing the instructions, performs a convolution operation on the basis of the input data and the plurality of constants.
G06F 7/544 - Méthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs n'établissant pas de contact, p. ex. tube, dispositif à l'état solideMéthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs non spécifiés pour l'évaluation de fonctions par calcul
G06F 30/327 - Synthèse logiqueSynthèse de comportement, p. ex. logique de correspondance, langage de description de matériel [HDL] à liste d’interconnections [Netlist], langage de haut niveau à langage de transfert entre registres [RTL] ou liste d’interconnections [Netlist]
G06N 3/063 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques
22.
CONVOLUTION OPERATION APPARATUS USING APPROXIMATE ALGORITHM-BASED UMCM CIRCUIT AND DESIGN METHOD THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Kihwan
Lee, Hyuk Jae
Jeon, Dongsuk
Nguyen, Xuan Truong
Abrégé
A convolution operation apparatus according to a first aspect of the present invention comprises: an input unit that receives input data as an input; a constant generation circuit that generates a plurality of constants and includes one or more nodes corresponding to each of the plurality of constants; a memory capable of storing computer-executable instructions; and a processor that performs a convolution operation on the basis of the input data that has been input and the plurality of constants, by executing the instructions. Here, the plurality of constants are determined by approximating a plurality of predetermined reference constants to a similar value between each reference constant and each reference constant less than or equal to a predetermined threshold, and the plurality of reference constants may be values corresponding to a plurality of weights that are predetermined through training of a neural network.
G06F 7/544 - Méthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs n'établissant pas de contact, p. ex. tube, dispositif à l'état solideMéthodes ou dispositions pour effectuer des calculs en utilisant exclusivement une représentation numérique codée, p. ex. en utilisant une représentation binaire, ternaire, décimale utilisant des dispositifs non spécifiés pour l'évaluation de fonctions par calcul
G06F 30/327 - Synthèse logiqueSynthèse de comportement, p. ex. logique de correspondance, langage de description de matériel [HDL] à liste d’interconnections [Netlist], langage de haut niveau à langage de transfert entre registres [RTL] ou liste d’interconnections [Netlist]
G06N 3/063 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques
23.
DIAGNOSIS AID DEVICE USING SMART HEMO-DYNAMIC INDEX AND METHOD THEREOF
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
KOREA VETERANS HEALTH SERVICE (République de Corée)
Inventeur(s)
Song, Si Mon
An, Don Gwan
Lee, Sang Hyung
Kim, Doo Sang
Abrégé
The present invention relates to a diagnostic aid device and method using smart hemodynamic indices and, more particularly, to a diagnostic aid device and method for aid in medical decision-making, by calculating smart hemodynamic indices, which is a combination of smart indices with hemodynamic indices, and providing diagnosis results according to quantitatively standardized clinical guidelines by using the smart hemodynamic indices.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
24.
POWER TRANSMISSION DEVICE, POWER RECEPTION DEVICE, AND WIRELESS POWER TRANSFER SYSTEM AND METHOD FOR ELECTRIC VEHICLE CHARGING
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Choe, Gyu Yeong
Ha, Jung Ik
Choi, Sung Hyuk
Abrégé
A power reception device is disposed in an electric vehicle to receive electric power from an electric vehicle supply equipment (EVSE). The power reception device includes: a first magnetic core portion being a part of a magnetic core and corresponding to a core of a primary coil in a power transmission device of the EVSE; a secondary coil wound around the first magnetic core portion; and a second magnetic core portion being another part of the magnetic core and extending from an end of the first magnetic core portion.
B60L 53/39 - Moyens pour l’ajustement automatique ou assisté de la position relative des dispositifs de charge et des véhicules spécialement adaptés au chargement en utilisant le transfert d'énergie par induction avec activation sensible à la position des bobines primaires
B60L 53/126 - Procédés pour associer un véhicule et une station de charge, p. ex. en établissant une relation directe entre un transmetteur d'énergie sans fil et un récepteur d'énergie sans fil
25.
DRY NEGATIVE ELECTRODE FOR LITHIUM SECONDARY BATTERY AND A METHOD OF MANFACTURING SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Cho, Yong Il
Song, Han Nah
Kim, Hyun Jin
Park, Chan Bum
Lee, Hyeon Ha
Lee, Young Soo
Choi, Jang Wook
Lee, Tae Geun
An, Ji Woo
Abrégé
Provided is a negative electrode for a lithium secondary battery, comprising a negative electrode active material and a fibrous binder. The negative electrode active material has an ID/IG value of about 0.18 or more and less than about 0.7 as a result of Raman spectroscopy analysis. The active material may be carbon-based and exhibit specific characteristics according to X-ray diffraction (XRD) analysis. The fibrous binder may be polytetrafluoroethylene (PTFE). Additionally, a method of manufacturing the negative electrode involves preparing a mixture of the active material and a binder precursor, then fiberizing the binder precursor by applying shear stress. The negative electrode may also include a conductive material. The disclosure further includes a lithium secondary battery comprising this negative electrode.
Samsung Electronics Co., Ltd. (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Lee, Jaehwan
Woo, Hyunchul
Yim, Hyungjoo
Lee, Dongjun
Lee, Youngseon
Ko, Seunghwan
Kim, Hyunsu
Lee, Cheolmin
Heo, Jinuk
Abrégé
An electronic device according to an embodiment may receive haptic data from an external electronic device through a communication circuit. The electronic device may control a plurality of heating elements based on an orientation indicated by the haptic data. The electronic device may control a plurality of vibration actuators based on the orientation and the timing at which the plurality of heating elements are controlled.
G08B 6/00 - Systèmes de signalisation tactile, p. ex. systèmes d'appel de personnes
H05B 1/02 - Dispositions de commutation automatique spécialement adaptées aux appareils de chauffage
27.
CELL SIGNAL MEASURING DEVICE COMPRISING FIELD EFFECT TRANSISTOR TO WHICH VERTICAL NANOSTRUCTURE IS APPLIED, AND MANUFACTURING AND OPERATING METHOD THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Yi, Gyuchul
Lee, Jamin
Kang, Kyumeen
Abrégé
A cell signal measuring device and a manufacturing and operating method thereof are disclosed. The disclosed cell signal measuring device may be a cell signal measuring device comprising a vertical field effect transistor, wherein the vertical field effect transistor includes: a drain electrode including a two-dimensional nanomaterial; a vertical nanostructure vertically disposed on the drain electrode; a source electrode disposed to make electrical contact with the top of the nanostructure or an area adjacent thereto; a gate insulating layer disposed on the surface of the nanostructure; a gate electrode disposed on the gate insulating layer between the drain electrode and the source electrode so as to encompass a part of the nanostructure; and a separation layer filling the space between the gate electrode and the source electrode. The cell signal measuring device can: cause the source electrode to make contact with a cell or penetrate thereinto so as to measure a signal of the cell; and change a gate voltage applied to the gate electrode, so as to adjust the intensity of the signal measured from the cell.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Sangbum
Joe, Changhoon
Byun, Kanghyeon
Abrégé
An analog data similarity search memory device and an operating method thereof are disclosed. The disclosed analog data similarity search memory device comprises: a data storage block which stores an analog input voltage and which is connected to a first terminal of a data line; and a matching block which is connected to a second terminal of the data line, and which includes a match line for outputting an analog matching distance value corresponding to the voltage difference between the analog input voltage and an analog search voltage applied through a search line, wherein the voltage difference between the analog input voltage and the analog search voltage can be generated through the data line.
G11C 15/04 - Mémoires numériques dans lesquelles l'information, comportant une ou plusieurs parties caractéristiques, est écrite dans la mémoire et dans lesquelles l'information est lue au moyen de la recherche de l'une ou plusieurs de ces parties caractéristiques, c.-à-d. mémoires associatives ou mémoires adressables par leur contenu utilisant des éléments semi-conducteurs
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Park, Yoon Jeong
Chung, Chong-Pyoung
Lee, Jue-Yeon
Kim, Sungtae
Cho, Young-Dan
Lee, Dong Woo
Abrégé
The present invention provides a dental composition comprising BMP9 to be used in regenerating dental tissue or periodontal tissue, or a method for regenerating dental tissue or periodontal tissue, comprising administering BMP9 to a subject requiring the regeneration of dental tissue or periodontal tissue. The dental tissue can be dentin, and the periodontal tissue can be cementum, alveolar bone, or periodontal ligament. BMP9 according to the present invention is effective, as exhibited by experimental results, in promoting dentin regeneration and periodontal tissue regeneration for teeth.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
A61C 8/02 - Moyens pour la transfixation des dents naturelles
A61C 8/00 - Moyens destinés à être fixés à l'os de la mâchoire pour consolider les dents naturelles ou pour y assujettir des prothèses dentairesImplants dentairesOutils pour l'implantation
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
BRAIN & BEYONDS CO., LTD. (République de Corée)
Inventeur(s)
Paek, Sun Ha
Kim, Yona
You, Ji Hyeon
Park, Soon Beom
Abrégé
The present disclosure provides a pharmaceutical composition comprising a NUPR1 isoform A inhibitor as an active ingredient. Pharmaceutical compositions comprising an NUPR1 isoform A inhibitor may be used in methods of preventing or treating cancer, in methods of diagnosing or predicting prognosis of cancer comprising an agent for measuring an expression or activity level of a NUPR1 isoform A, in a kit for diagnosing or predicting prognosis of cancer comprising the composition, methods for screening a substance for inhibiting cancer cell proliferation or metastasis, methods for providing information for cancer cell proliferation or metastasis, in food compositions for preventing or improving cancer comprising a NUPR1 isoform A inhibitor as an active ingredient, and in feed compositions for preventing or improving cancer comprising a NUPR1 isoform A inhibitor as an active ingredient.
A61K 31/541 - Thiazines non condensées contenant d'autres hétérocycles
A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
A61P 5/00 - Médicaments pour le traitement des troubles du système endocrinien
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61P 13/08 - Médicaments pour le traitement des troubles du système urinaire de la prostate
A61P 15/08 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs pour les troubles gonadiques ou pour augmenter la fertilité, p. ex. inducteurs d'ovulation ou de spermatogénèse
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
31.
CAPACITOR, METHOD OF MANUFACTURING THE SAME, AND DEVICE INCLUDING CAPACITOR
Seoul National University R&DB foundation (République de Corée)
Inventeur(s)
Hwang, Cheol Seong
Abrégé
The present disclosure provides a capacitor including a first electrode, a second electrode disposed spaced apart from the first electrode, a dielectric layer disposed between the first electrode and the second electrode and including strontium titanium oxide, and a buffer layer disposed between the first electrode and the dielectric layer, wherein the buffer layer may include germanium oxide and a germanium material portion, and the germanium material portion may be composed of germanium uncombined with oxygen.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Jung, Heon Hui
Paek, Yunheung
Nam, Kevin
Ha, Seungjin
Shin, Junbum
Yu, Inkwan
Jung, Sunchul
Seo, Jungjoo
Abrégé
An electronic apparatus includes: a communication device; a memory storing a first secret key and a first public key corresponding to the first secret key, and storing at least one instruction; and a processor configured to execute the at least one instruction, wherein the processor is configured to generate a switching key based on a second public key and the first secret key if the processor receives the second public key from a terminal device corresponding to a first user, and control the communication device to transmit the first public key to the terminal device, the switching key being a key that enables a homomorphic ciphertext encrypted using the first public key to be decrypted using a second secret key corresponding to the second public key.
H04L 9/14 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité utilisant plusieurs clés ou algorithmes
H04L 9/30 - Clé publique, c.-à-d. l'algorithme de chiffrement étant impossible à inverser par ordinateur et les clés de chiffrement des utilisateurs n'exigeant pas le secret
33.
METHOD OF TRAINING IMAGE RESTORATION MODEL AND IMAGE RESTORATION APPARATUS FOR PERFORMING THE SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Chun, Se Young
Park, Dongwon
Kim, Ha Yeon
Abrégé
The embodiments disclosed herein are directed to a method of training an image restoration model and an image restoration apparatus for performing the same. According to an embodiment, the method is performed by an image restoration apparatus, and the method includes: pre-training an image restoration model by generating training images by randomly applying a plurality of synthetic degradation functions to a clean image; and fine-tuning parameters of the pre-trained image restoration model through contribution-based low-rank adaptation for an image restoration task; wherein fine-tuning the parameters includes fine-tuning parameters of each layer of the image restoration model based on the ratio of learnable network parameters, determined according to the contribution of each layer of the pre-trained image restoration model, and low-rank adaptation for the image restoration task.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Baek, Jongseok
Park, Taeyoung
Maeng, Junyeol
Cui, Shenghui
Abrégé
A power conversion apparatus included in a home appliance and including a converter configured to convert an AC power source into DC power and output the DC power to a DC terminal; a DC link capacitor connected to the DC terminal and configured to store DC power from the converter; an inverter configured to convert DC power from the DC link capacitor into AC power and output the converted AC power to a compressor; and a bandpass filter damper disposed between the input AC power source and the DC link capacitor and configured to allow a predetermined range of frequencies to pass through. Further, the bandpass filter damper is electrically connected to a ground of the input AC power source, thereby reducing the amount of leakage current flowing to the system ground.
H02M 5/42 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant alternatif, p. ex. pour changement de la tension, pour changement de la fréquence, pour changement du nombre de phases avec transformation intermédiaire en courant continu par convertisseurs statiques
H02M 1/44 - Circuits ou dispositions pour corriger les interférences électromagnétiques dans les convertisseurs ou les onduleurs
H03H 7/01 - Réseaux à deux accès sélecteurs de fréquence
H03H 7/06 - Réseaux à deux accès sélecteurs de fréquence comprenant des résistances
35.
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING COLORECTAL CANCER, COMPRISING ESTROGEN AND ANTI-PD-L1 ANTIBODY
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
Inventeur(s)
Kim, Nayoung
Nam, Ryoung Hee
Song, Chin-Hee
Abrégé
The present invention relates to a pharmaceutical composition for preventing or treating colorectal cancer comprising estrogen and an anti-PD-L1 antibody, and a composition comprising estrogen for promoting anti-cancer effects of an anti-PD-L1 antibody. Particularly, a combination therapy of estrogen and an anti-PD-L1 antibody carried out in a colorectal cancer model exhibits synergistic effects in tumor growth inhibition that are greater than those of when each is used alone, and induces changes in tumor-related cell populations, and thus is effective as a treatment in precision medicine.
A61K 31/566 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes non substitués en position 17 bêta par un atome de carbone, p. ex. œstrane, œstradiol ayant un groupe oxo en position 17, p. ex. œstrone
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
36.
COMPENSATION CIRCUIT FOR STRETCHABLE DISPLAY AND STRETCHABLE DISPLAY INCLUDING SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Soo Yeon
Kang, Ji Min
Abrégé
The present invention relates to a micro LED driving circuit comprising a double gate transistor, and comprises: a PWM circuit unit for adjusting the light emission time of a micro LED; and a CCG circuit unit for controlling, on the basis of PWM data voltage, that a certain current is supplied during light emission of the micro LED.
G09G 3/00 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques
G06F 3/044 - Numériseurs, p. ex. pour des écrans ou des pavés tactiles, caractérisés par les moyens de transduction par des moyens capacitifs
G09G 3/3233 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED] organiques, p. ex. utilisant des diodes électroluminescentes organiques [OLED] utilisant une matrice active avec un circuit de pixel pour commander le courant à travers l'élément électroluminescent
37.
LIGHT-EMITTING DIODE (LED) DEVICE, METHOD OF MANUFACTURING THE SAME, AND DISPLAY DEVICE INCLUDING THE LED DEVICE
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Hwang, Kyungwook
Jang, Ho Won
Hwang, Junsik
Abrégé
An LED device includes a light emission layer including a first semiconductor layer including a first surface and a second surface facing the first surface, the second surface having an area larger than an area of the first surface, an active layer on the first surface, and a second semiconductor layer on the active layer, an insulating layer on the first surface, the insulating layer defining an open region of the first semiconductor layer, a first electrode that contacts the first semiconductor layer via the open region, and a second electrode on the second semiconductor layer and contacting the second semiconductor layer.
H10H 20/832 - Électrodes caractérisées par leurs matériaux
H10H 29/14 - Dispositifs intégrés comprenant au moins un composant émetteur de lumière à semi-conducteurs couvert par le groupe comprenant plusieurs composants émetteurs de lumière à semi-conducteurs
38.
SINGLE NUCLEOTIDE POLYMORPHISM MARKER ASSOCIATED WITH REDUCTION IN REY COMPLEX FIGURE COPY SCORE FOR PREDICTING RISK OF DEVELOPING ALZHEIMER'S DISEASE AND USE THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (République de Corée)
Inventeur(s)
Won, Sung Ho
Lee, Kunho
Park, Jun Young
Abrégé
The present invention relates to: a method for providing information which can diagnose early and predict groups with the risk of developing Alzheimer's disease by providing SNP markers capable of predicting a high risk of developing Alzheimer's disease in Koreans; a composition for predicting the risk of developing Alzheimer's disease; and a microarray and a kit, each comprising same.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
C12Q 1/6837 - Couplage enzymatique ou biochimique d’acides nucléiques à une phase solide utilisant des réseaux de sondes ou des puces à sondes
39.
NOVEL PEPTIDE HAVING BINDING AFFINITY TO ANGIOTENSIN-CONVERTING ENZYME 2(ACE2) AND USES THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Chung, Chong-Pyoung
Park, Yoon Jeong
Lee, Jue-Yeon
Jo, Beom Soo
Yoon, Gookjin
Choi, Moonsil
Jeong, Eui Kyun
Lee, Hoo Cheol
Abrégé
The present invention relates to a novel peptide having binding affinity to ACE2 and uses thereof and, more specifically, to: a peptide represented by any one amino acid sequence selected from the group consisting of SEQ ID NOs: 1 to 4, and having binding affinity to ACE2; a nanocarrier and a drug complex, each comprising the peptide; and a pharmaceutical composition for preventing or treating COVID-19, comprising the peptide, the nanocarrier, or the drug complex. The novel peptide according to the present invention can be used to increase the COVID-19 therapeutic effect through specific binding to ACE2-expressing cells.
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 31/451 - Pipéridines non condensées, p. ex. pipérocaïne ayant un carbocycle lié directement à l'hétérocycle, p. ex. glutéthimide, mépéridine, lopéramide, phencyclidine, piminodine
A61P 31/14 - Antiviraux pour le traitement des virus ARN
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sangheon
Lee, Dongwoo
Choi, Kiyoung
Ryu, Soojung
Abrégé
A memory controller includes a dirty group detector configured to, in response to receiving a request for writing data to a memory, modify addresses of a cache group related to a physical address of the memory, increase counters corresponding to the modified addresses of the cache group, and detect whether the cache group is in a dirty state based on the counters; and a dirty list manager configured to manage the cache group in the dirty state and a dirty list including dirty bits according to a result of the detecting; wherein the dirty bits indicate whether a cache set included in the cache group is in the dirty state.
G06F 12/126 - Commande de remplacement utilisant des algorithmes de remplacement avec maniement spécial des données, p. ex. priorité des données ou des instructions, erreurs de maniement ou repérage
G06F 12/0895 - Mémoires cache caractérisées par leur organisation ou leur structure de parties de mémoires cache, p. ex. répertoire ou matrice d’étiquettes
41.
METHOD AND DEVICE FOR PREDICTING SHAPE OF DNA STRUCTURE BASED ON DEEP LEARNING
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Do Nyun
Lee, Jae Young
Chien, Truong-Quoc
Abrégé
In a method for predicting a shape of a DNA structure based on deep learning, a DNA structure graph having nodes and edges based on a DNA structure design is acquired. A DNA structure shape corresponding to the DNA structure design based on the DNA structure graph and a DNA structure shape prediction model is output.
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A61K 31/501 - PyridazinesPyridazines hydrogénées non condensées et contenant d'autres hétérocycles
43.
NOVEL APOE ANTISENSE OLIGONUCLEOTIDE AND USE THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Mook-Jung, Inhee
Jung, Eun Sun
Han, Jihui
Abrégé
The present invention relates to: an apolipoprotein E (APOE) antisense oligonucleotide; and a pharmaceutical composition for treating Alzheimer's disease comprising same. The antisense oligonucleotide of the present invention can reduce the expression of the APOE4 variant gene that contributes to increased risk and exacerbation of Alzheimer's disease, and can be used as an RNA therapeutic agent for diseases caused by abnormal levels of APOE proteins or APOE variant genome expression.
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
44.
COMPOSITION FOR PROMOTING MYOGENESIS AND MANUFACTURING METHOD THEREFOR
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Park, Chung Gyu
Kim, Jung Sik
Abrégé
The present invention relates to a novel anti-CD40 antibody and use thereof and, more specifically, to a novel anti-CD40 antibody and use thereof, wherein the antibody comprises a complementarity determining region of a specific sequence and exhibits an excellent antagonistic effect by blocking CD40-CD40L signaling. The novel anti-CD40 antibody of the present invention exhibits an excellent antagonistic effect by blocking CD40-CD40L signaling, and thus can be widely used as a preparation for preventing or treating various diseases, such as autoimmune diseases and chronic inflammatory diseases, and as a preparation for inhibiting immune rejection at the time of transplantation.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
C12N 5/12 - Cellules fusionnées, p. ex. hybridomes
A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
46.
PEPTIDE-BASED PROBES FOR DIAGNOSIS OF DISEASE AND USES THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Chung, Chong-Pyoung
Park, Yoon Jeong
Lee, Jue-Yeon
Jo, Beom Soo
Yoon, Gook-Jin
Lee, Dong Woo
Abrégé
The present invention relates to a probe in which a fluorescence dye-quencher is additionally bound to a fusion peptide to which a cell-penetrating peptide-biomarker binding functional peptide for diseases is bound and, more particularly, to a cell-penetrating peptide-bioactive peptide molecular probe which directly introduces a non-penetrating disease-sensitive important domain into a cell so as to penetrate a target cell and emit fluorescence when bound to a target material, thereby facilitating diagnosis and simultaneously inducing treatment. According to the present invention, compared to conventional staining-based histological disease diagnosis, diseases, such as inflammation, can be identified in a non-invasive and rapid manner, and thus the probe may be useful in diagnosing various inflammatory diseases or monitoring transplant-related inflammatory responses during in vivo transplantation. Also, the probe is applicable to clinical use without undergoing multiple steps and can be mass-produced, and thus, by using this approach, is useful in the development of drug delivery systems and treatment technologies.
LIQUID ADDITIVE WITH HIGH LITHIUM ION CONDUCTIVITY AND LOW REACTIVITY WITH SOLID ELECTROLYTE, AND ALL-SOLID-STATE BATTERY CAPABLE OF OPERATING AT ROOM TEMPERATURE AND LOW PRESSURE INCLUDING SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Ji Young
Son, Sam Ick
Bae, Ki Yoon
Choi, Jang Wook
Lee, Noh Joon
Oh, Ji Hoon
Sohn, Ye Eun
Abrégé
A liquid additive for an all-solid-state battery capable of operating under conditions of room temperature and low pressure, and an all-solid-state battery including the same. Specifically, by adding a liquid additive having low reactivity with a solid electrolyte and high lithium ion conductivity to an anode layer, a cathode layer, or a solid electrolyte layer, ionic conductivity and current density robustness of the all-solid-state battery can be improved under conditions of room temperature and low pressure.
H01M 10/056 - Accumulateurs à électrolyte non aqueux caractérisés par les matériaux utilisés comme électrolytes, p. ex. électrolytes mixtes inorganiques/organiques
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
48.
METHOD AND APPARATUS WITH HOMOMORPHIC ENCRYPTION OPERATION
Samsung Electronics Co., Ltd. (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Song, Yongsoo
Min, Seonhong
Lee, Dongwon
Abrégé
A method and apparatus for a homomorphic encryption operation are disclosed. A bootstrapping method for a homomorphically encrypted ciphertext includes generating a first ciphertext of a plaintext corresponding to a ciphertext modulus of a third value, based on an input ciphertext of the plaintext corresponding to a ciphertext modulus of a first value and corresponding to a ciphertext modulus of a second value, generating a second ciphertext corresponding to the ciphertext modulus of the second value and corresponding to the ciphertext modulus of the third value, based on the first ciphertext, the second value, and the third value, and generating a third ciphertext of an evaluation result of a target function for the plaintext corresponding to a plaintext modulus of a fourth value, based on the second ciphertext and the target function.
H04L 9/06 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité l'appareil de chiffrement utilisant des registres à décalage ou des mémoires pour le codage par blocs, p. ex. système DES
H04L 9/00 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité
H04L 9/30 - Clé publique, c.-à-d. l'algorithme de chiffrement étant impossible à inverser par ordinateur et les clés de chiffrement des utilisateurs n'exigeant pas le secret
Samsung Electronics Co., Ltd. (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Kim, Taehoon
Han, Bohyung
Jang, Donghwan
Abrégé
A method and apparatus for incremental learning are provided. The method includes performing training of a model for a specific task, calculating an average value of a parameter of the model before training for the specific task and calculating a parameter of the model updated by performing training for the specific task, and changing a parameter of the model to the calculated average value.
C07D 401/12 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
51.
DEVICE AND METHOD FOR WATER ELECTROLYZER CAPABLE OF SIMULTANEOUS DESALINATION THROUGH NANOELECTROKINETIC ION CONCENTRATION POLARIZATION
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Sung Jae
Park, Ji Hee
Yoon, Se Hyuk
Ha, Sungjae
Abrégé
Provided is an apparatus and a method of desalinating saltwater and transporting hydrogen ions using Ion Concentration Polarization (ICP), the apparatus including: a channel part including a channel allowing saltwater to be introduced thereinto, an ion-selective membrane connected to the channel, and a cathode and an anode for applying a voltage to both ends of the channel; a desalination part configured to obtain fresh water from the saltwater with ionic substances removed from the saltwater by ion concentration polarization in a first region adjacent to the anode of the ion-selective membrane; and a hydrogen gas production part configured to concentrate the ionic substances in a second region adjacent to the cathode of the ion-selective membrane and to reduce hydrogen ions (H+) contained in the ionic substances.
C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
Seoul National University R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Jong-Ho
Im, Jiseong
Ko, Jonghyun
Abrégé
Provided is an analog-to-digital converter. The ADC includes a plurality of bit detection units. Each of the bit detection unit comprises: a state level determination module including a semiconductor device with a preset threshold voltage to receive an input signal; and an output module connected to the state level determination module and configured to detect and output a binary value corresponding to the input voltage. The bit detection units are configured to match one-to-one with the bits constituting a digital code, respectively. The state level determination module is configured to have a threshold voltage or conductance determined according to the bit of the digital code matched to the bit detection unit. Each of the bit detection units detects and outputs a binary value corresponding to the matched bit of the digital code from the input signal.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Ko, Gwang Pyo
Kim, Woon Ki
Min, Sung Gyu
Abrégé
The present invention relates to novel Bifidobacterium longum SNUG50180, SNUG50432, and SNUG50527, and, more specifically, to: Bifidobacterium longum SNUG50180 having the effects of improving intestinal health and treating or preventing intestinal diseases, Bifidobacterium longum SNUG50432 having an effect of promoting immune anticancer activity and Bifidobacterium longum SNUG50527 having an effect of treating or preventing cancer, which are Bifidobacterium longum strains isolated from the feces of Korean individuals who have not taken antibiotics for at least 6 months; and uses thereof.
A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kang, Jong Hun
Kim, Do Heui
Jeong, Yangho
Lim, Yong Hyun
Ryu, Hae Won
Choi, Eun Ji
Abrégé
Provided are a zeolite-supported catalyst and a manufacturing method thereof. The zeolite-supported catalyst comprises zeolite and a metal catalyst supported on the zeolite. The zeolite is treated with quaternary ammonium hydroxide before supporting the metal catalyst, and thus has an increase in mesopores and a reduction in Al sites on the outer surface. The manufacturing method of the zeolite-supported catalyst comprises the steps of: preparing zeolite; base-treating the zeolite with quaternary ammonium hydroxide; and supporting a metal catalyst on the base-treated zeolite.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Taehyun
Lee, Jeonghoon
Abrégé
A quantum computing device according to an aspect of the present disclosure includes an ion trap chip including direct current (DC) electrodes and radio frequency (RF) rails to form a plurality of horizontal traps and one or morevertical traps, and a controller configured to trap ions by controlling the ion trap chip, adjust positions of the ions, and apply laser beam to the ions to perform gate operations. The controller performs traversal gate operations between qubits arranged in the horizontal trap area based on qubit connectivity of only qubits trapped in the same horizontal trap, moves the qubits arranged in the horizontal trap area to the vertical trap adjacent to the horizontal trap area through parallel shuttling, perform quantum error correction, and continues traversal gate operations after shuttling to an adjacent horizontal trap area through parallel shuttling.
G06N 10/70 - Correction, détection ou prévention d’erreur quantique, p. ex. codes de surface ou distillation d’état magique
G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit
56.
LINK PREDICTION METHOD AND APPARATUS USING ACCURATE LINK PREDICTION MODEL BASED ON POSITIVE-UNLABELED DATA LEARNING
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kang, U
Kim, Junghun
Park, Kahyun
Yoon, Hoyoung
Abrégé
Proposed herein are a link prediction method and apparatus. The link prediction method that is performed by the link prediction apparatus includes predicting one or more edges having a probability of being connected in the structure of an edge-incomplete graph by entering the edge-incomplete graph into a link prediction model. The link prediction model is a model that performs binary classification by processing at least one edge observed in the structure of the edge-incomplete graph as positive data and processing at least one node pair unconnected in the structure of the edge-incomplete graph as unlabeled data.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Tae-Woo
Kim, Sungjin
Lee, Hyeon-Dong
Woo, Seung-Je
Abrégé
The present invention relates to a tandem light-emitting device and a manufacturing method thereof. The tandem light-emitting device according to the present invention and a display device comprising same have maximized color purity and luminous efficiency, improved on-off response, superb operation life, and low manufacturing costs. In addition, the method for manufacturing a tandem light-emitting device according to the present invention has low manufacturing costs, and can manufacture the tandem light-emitting device of the present invention.
H10K 50/13 - OLED ou diodes électroluminescentes polymères [PLED] caractérisées par les couches électroluminescentes [EL] spécialement adaptées à l'émission de lumière multicolore, p. ex. à l'émission de lumière blanche comprenant des couches EL empilées dans une unité EL
H10K 30/15 - Dispositifs à semi-conducteurs sensibilisés à large bande interdite, p. ex. TiO2sensibilisé aux colorants
H10K 50/852 - Dispositifs pour extraire la lumière des dispositifs comprenant une structure de cavité résonante, p. ex. une paire de réflecteurs de Bragg
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Choi, Saerom
Park, Yutack
Kim, Jaesun
Han, Seungwu
Abrégé
A method including obtaining an input graph including a plurality of network components, where each of the plurality of network components include a plurality of nodes and a plurality of edges, segmenting the input graph into a plurality of partial input graphs, where the plurality of partial input graphs includes a first partial input graph and a second partial input graph, generating network features based on the plurality of partial input graphs, where each of the network features includes a connectivity relation between a network component and an adjacent network component among the plurality of network components in the input graph, transmitting a network feature from the first partial input graph to an adjacent network feature in the second partial input graph to obtain an aggregated network feature, and updating the network features of the plurality of network components based on the aggregated network feature.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Cha, Hyuk-Jin
Kim, Yun-Jeong
Abrégé
The present invention relates to a technique capable of selectively removing abnormal pluripotent stem cells by using metabolic characteristics thereof during stem cell culturing and, more specifically, to a technique capable of selectively removing only mutant pluripotent stem cells while minimizing effects on normal pluripotent stem cells by inducing ferroptosis. Provided in the present invention is a method for identifying metabolic characteristics caused by genetic mutations in genetically mutated pluripotent stem cells and easily and quickly removing the mutated pluripotent stem cells through treatment with a compound that acts on the metabolic characteristics, and thus the present invention can contribute to overcoming major technical limitations during the clinical use of pluripotent stem cells.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (République de Corée)
Inventeur(s)
Cha, Hyuk-Jin
Jo, Beom-Ki
Cho, Seung-Woo
Song, Young Seok
Abrégé
The present invention relates to novel lipid nanoparticles capable of liver-specific delivery of mRNA, a manufacturing method therefor, and a liver disease therapeutic agent capable of regenerating the liver by liver-specific delivery of the bio-reprogramming factor mRNA using same. The lipid nanoparticles according to the present invention allow for liver-specific delivery of mRNA at very high efficiency, and the lipid nanoparticles that encapsulate the mRNA-based bio-reprogramming factor mRNA are specifically delivered to liver tissues of an individual requiring liver regeneration to induce short-term expression, thereby easily setting the dose and expression period of a therapeutic agent, leading to a significant reduction in side effects of a therapeutic agent for liver regeneration using an existing cell reprogramming factor.
C12N 15/88 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p. ex. co-transformation utilisant la micro-encapsulation, p. ex. utilisant des vésicules liposomiques
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61K 38/00 - Préparations médicinales contenant des peptides
61.
MICROFLUIDIC CHIP FOR CELL CULTURE, COMPRISING PLURALITY OF CHANNELS
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Jeon, Noo Li
Jin, Ailian
Shim, Mi Kang
Abrégé
The present invention relates to a microfluidic chip for cell culture, comprising: an X-direction channel having at least a part extending in an X-direction; a Y-direction channel extending in a vertical direction across the X-direction channel; a Y-positive region channel formed to be in contact with the Y-direction channel in a Y-positive direction; a Y-negative region channel formed to be in contact with the Y-direction channel in a Y-negative direction; a Z-positive region channel formed to be in contact with the Y-direction channel in a Z direction; and a Y-positive direction reservoir surrounding the Y-positive region channel and in contact with the X-direction channel.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
62.
METHOD AND APPARATUS FOR PREDICTING BLOOD LOSS IN PATIENT UNDERGOING SURGERY
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
Inventeur(s)
Suh, Yun-Suhk
Yoo, Mira
Kim, Sungwan
Cho, Minwoo
Kong, Hyoun-Joong
Baek, Changhoon
Yoon, Dan
Kim, Byeong Soo
Kim, Young Gyun
Lee, Jong Hyeon
Abrégé
Provided are a method and an apparatus for predicting blood loss in a patient undergoing surgery. The method for predicting blood loss comprises the steps of: detecting a gauze image from a first image of a surgical site of a patient; setting a reference blood color of the patient on the basis of the first image; inputting the reference blood color and the gauze image to a pre-trained blood loss estimation model to estimate the ratio of blood and body fluid absorbed in the gauze; and predicting the amount of lost blood absorbed in the gauze on the basis of the estimated ratio of blood and body fluid.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
63.
COMPOSITION FOR PREVENTING OR TREATING ALTERNATIVE LENGTHENING OF TELOMERES-POSITIVE CANCER OR AGING
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Hyunsook
Lee, Jennifer Jaeun
Kim, Hyungmin
Jeon, Sara
Joo, So Young
Lee, Su Hyun
Choi, Siyoung
Jung, Sung Won
Abrégé
The present invention relates to a method for preventing or treating alternative lengthening of telomeres-positive cancer by identifying factors involved in alternative lengthening of telomeres and correlations therebetween, and by regulating expression of the factors. The present invention provides an effective therapeutic target for alternative lengthening of telomeres-positive cancer, for which an effective treatment method has not yet been developed due to the previously unclear mechanism. Accordingly, the present invention can be effectively used for efficient prevention or treatment of alternative lengthening of telomeres-positive cancer by regulating expression of the target.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Choi, Byung San
Yoon, Tae Young
Kim, Jin-Hong
Yoo, Dongwon
Seo, Youngran
Kim, Tae Gyun
Ahn, Jeong Hyun
An, Hyoung Tae
Kim, Ji Eun
Cho, Yongsik
Jeong, Sehan
Abrégé
The present invention provides a novel compound and a pharmaceutical composition comprising same for preventing or treating diseases associated with a reduction in Sox9 expression. Accordingly, the diseases associated with a reduction in Sox9 expression can be effectively prevented or treated.
C07D 417/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
A61K 31/427 - Thiazoles non condensés et contenant d'autres hétérocycles
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A61K 31/422 - Oxazoles non condensés et contenant d'autres hétérocycles
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
C07D 417/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
C07D 277/46 - Radicaux amino ou imino acylés par les acides carboxyliques ou par leurs analogues du soufre ou de l'azote
C07D 413/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
65.
IFI16 MUTANT GENE AS A MARKER FOR RISK PREDICTION, DIAGNOSIS OR PROGNOSIS OF CHRONIC LIVER DISEASE AND USES THEREOF
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION (République de Corée)
ON HOSPITAL (République de Corée)
Inventeur(s)
Lee, Yeon Su
Park, Gaeul
Lee, Yong Sun
Woo, Hyun Goo
Kim, Do Yoon
Seong, Rho Hyun
Baek, Yang Hyun
Han, Sang Young
Abrégé
An Interferon Gamma Inducible Protein 16 (IFI16) mutant gene and its use as a marker for predicting, diagnosing, or prognosticating risk or severity of chronic liver disease is described. As a result of performing genomic analysis on NAFLD and NASH patient groups, it was confirmed that the frequency of IFI16 single-nucleotide variants (SNVs) including rs2276404, rs73021847, rs7532207, and rs6940 was increased, and the expression of the IFI16 mutant gene was increased depending on the disease stage of liver disease. The IFI16 SNV was highly expressed in infiltrating macrophages, playing a role in macrophage-induced inflammatory processes, and the IFI16 variant bound more strongly to dsDNA than wild-type IFI16, exacerbating the impaired mitochondrial DNA-sensing response signaling of the IFI16-PYCARD-CASP1 pathway. Thus, the IFI16 mutant gene may be used for predicting, diagnosing, or prognosticating risk or severity of chronic liver disease.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
66.
RECOMBINANT VIBRIO NATRIEGENS CAPABLE OF ALGINIC ACID METABOLISM AND METHOD FOR PRODUCING ISOPENTENOL USING SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Seo, Sang Woo
Lee, Yungyu
Abrégé
Vibrio natriegensVibrio natriegens, which cannot naturally metabolize alginic acid, is transformed to be capable of alginic acid metabolism and used to produce isopentenol. A recombinant Vibrio natriegens imparted with the ability to metabolize alginic acid and provided with an additional isopentenol production pathway was developed and can be used to metabolize alginic acid and produce isopentenol with high productivity.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Yun Sang
Chung, Yujin
Seok, Seung Hyeok
Chung, Hyewon
Park, Jisu
Park, Ji Yong
Yoo, Ran Ji
Kim, Kyuwan
Kim, Ji Yoon
Kim, Jin Sil
Abrégé
The present invention relates to a surface-modified albumin nano-platform, a method for preparing same, and a composition for diagnosing or treating a disease using same. The surface-modified albumin nano-platform according to the present invention can reduce ingestion by the reticuloendothelial system even when an excess amount of click-functional groups and various delivery substances are conjugated to albumin, by inactivating a click reaction functional group to which a delivery substance on the surface of albumin is not bound, so that the in vivo half-life is greatly increased, and a target molecule or an active substance can be effectively delivered to a target tissue or cell, leading to excellent therapeutic and diagnostic effects.
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Park, Yong Lae
Kim, Jae In
Choi, Jaeyoun
Kim, Junhyung
Abrégé
Disclosed is a multi-DOF wearable assistance device, which is worn on a human body and assists movement, including: a plurality of blocks arranged to be spaced apart along the human body; a linear actuator disposed left and right in parallel between the neighboring blocks; and a joint connector providing a joint connection to freely change a connection angle between the block and opposite ends of the linear actuator.
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Jeong, Shin Hyun
Yun, Jae Kwang
Lee, Kwang Yeon
Kim, Suhwan
Lee, Dongsoo
Yang, Sunggi
Abrégé
A time-to-digital converter (TDC) circuit, according to one embodiment of the present invention, may comprise: a processing circuit which generates a first value of a first gain signal indicating a first time sensing range in a first mode and a first value of a second gain signal indicating a second time sensing range in the first mode; a first delay circuit which generates a plurality of first delay signals by delaying an input signal on the basis of the first value of the first gain signal; a first arbiter circuit which generate first results based on each of the plurality of first delay signals and a first clock signal; a second delay circuit which generates a plurality of second delay signals by delaying the input signal on the basis of the first value of the second gain signal; a second arbiter circuit which generates second results based on each of the plurality of second delay signals and the first clock signal; and an adder circuit which generates a first sum result on the basis of the first results and the second results.
H03M 1/50 - Convertisseurs analogiques/numériques avec conversion intermédiaire en intervalle de temps
H03L 7/085 - Détails de la boucle verrouillée en phase concernant principalement l'agencement de détection de phase ou de fréquence, y compris le filtrage ou l'amplification de son signal de sortie
71.
METHOD AND DEVICE FOR VISIBLE REGION ALLOCATION IN COMMUNICATION SYSTEM HAVING XL-MIMO ANTENNAS
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Jeong Su
Hong, Ui Hyun
Suh, Young Kil
Hahn, Gene Back
Kim, Dong Hwi
Kwon, Jeonghyeon
Choi, Wan
Abrégé
This method of a base station for allocating a visible region (VR) in a communication system having a plurality of antennas may comprise the steps of: acquiring location information of a second UE making an initial access; selecting, from among UEs communicating with the base station, a first UE, which is closest to the second UE; transmitting a first RS to the second UE through a first VR allocated to the first UE from among XL-MIMO antennas; receiving, from the second UE, a first report message including a measurement value for the first RS measured by the second UE; and allocating the first VR to the second UE if it is determined, on the basis of the first report message, that the second UE can use the first VR, and the first UE and the second UE can share the first VR through a multiplexing method.
H04B 7/0452 - Systèmes MIMO à plusieurs utilisateurs
H04W 72/044 - Affectation de ressources sans fil sur la base du type de ressources affectées
H04W 72/51 - Critères d’affectation ou de planification des ressources sans fil sur la base des propriétés du terminal ou du dispositif
H04W 72/542 - Critères d’affectation ou de planification des ressources sans fil sur la base de critères de qualité en utilisant la qualité mesurée ou perçue
H04W 72/543 - Critères d’affectation ou de planification des ressources sans fil sur la base de critères de qualité sur la base de la qualité demandée, p. ex. QdS [QoS]
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Choi, Woo Young
Woo, Jae Seung
Park, Geuntae
Abrégé
A nano electromechanical neuron device based on a spiking neural network, includes: a first gate electrode receiving a first voltage; a second gate electrode disposed in parallel and spaced apart from the first gate electrode and receiving a second voltage; a drain electrode disposed at a predetermined distance from one end of the first gate electrode and receiving a spike current signal; a movable beam disposed between the first and second gate electrodes and bending in a direction toward the drain electrode according to a spike current signal; and an anchor for securing the movable beam to a lower layer.
G06N 3/049 - Réseaux neuronaux temporels, p. ex. éléments à retard, neurones oscillants ou entrées impulsionnelles
73.
Beam Control Method Using Multi-Sensor in Millimeter-Wave and Terahertz-Wave Wireless Communication System, and Recording Medium and Device for Performing Same
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Shim, Byonghyo
Ahn, Yongjun
Kim, Jinhong
Kim, Junhan
Kim, Seungnyun
Shim, Kyuhong
Kim, Jiyoung
Abrégé
A beam control method using a multi-sensor in a millimeter-wave and terahertz-wave wireless communication system comprises the steps of: diving a beamforming region and performing beam sweeping by a base station; specifying, through beam sweeping, a divided region in which the strength of a received signal is the strongest; obtaining image information through at least one sensor included in a wireless terminal or a base station located in the specified divided region; identifying a target terminal to be communicated, by using the obtained image information, and extracting location information of the identified target terminal; and transmitting data in a direction corresponding to the location information of the identified target terminal. Accordingly, it is possible to greatly increase the accuracy of beamforming in a wireless communication environment, and reduce power consumption, a radio resource overhead, and a delay time required for beamforming.
H04B 7/06 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission
H04W 64/00 - Localisation d'utilisateurs ou de terminaux pour la gestion du réseau, p. ex. gestion de la mobilité
74.
METHOD FOR PROVIDING USER INTERFACE FOR CONTROLLING MAGNETIC CATHETER BY CHANGING EXTERNAL MAGNETIC FIELD, AND DEVICE FOR PROVIDING USER INTERFACE USING SAME
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Yoon, Chang Hwan
Ha, Jung Ik
Lee, Sang Won
Abrégé
A method for providing a user interface for controlling a magnetic catheter by changing an external magnetic field, including steps of: acquiring a k-th subject spatial image by photographing a subject space from a k-th subject spatial absolute coordinate point, displaying a k-th selection indicating symbol at a k-th subject spatial relative coordinate point, which is a relative coordinate point selected by a user with respect to the k-th subject spatial absolute coordinate point as its origin, displaying a k-th visualized coordinate space to expose a yaw and a pitch of a current direction of the magnetic catheter, and continuously exposing the yaw and the pitch of the current direction of the magnetic catheter as time passes.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Kyunghan
Lee, Jong Yun
Abrégé
A stream control system for many-to-many streaming services includes a plurality of client devices receiving a bitrate map including identification information for at least one transmitting client device from a media server, grade information of a transmission stream transmitted by each transmitting client device, and bitrate information for each grade of the transmission stream, generating a selection table including a plurality of combinations of reception streams and selecting a combination of reception streams based on a frame delay time, and a media server receiving encoded media from at least one transmitting client device and transmitting the media to at least one receiving client device, wherein the client device determines the frame delay time based on transmission start time information inserted into a media frame received from the transmitting client device and an arrival time of the media frame.
H04L 65/613 - Diffusion en flux de paquets multimédias pour la prise en charge des services de diffusion par flux unidirectionnel, p. ex. radio sur Internet pour la commande de la source par la destination
76.
DEVICE AND METHOD WITH NEURAL NETWORK DEPTH COMPRESSION
Samsung Electronics Co., Ltd. (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Kim, Jin Uk
Song, Hyun Oh
Abrégé
An electronic device includes one or more processors configured to measure importance and inference time for a plurality of blocks in which consecutive linear layers are merged, detect a location of a nonlinear layer maximizing the importance when the inference time is limited, using a dynamic programming algorithm, remove the remaining nonlinear layers except for the nonlinear layer at the detected location, and merge adjacent linear layers by removing the remaining nonlinear layers.
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
DREAMPAC CORPORATION (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY (République de Corée)
INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (République de Corée)
PRECISION MEDICINE FOR PERITONEAL METASTASIS COOPERATIVE (République de Corée)
INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY (République de Corée)
Inventeur(s)
Kim, Hee Seung
Park, Soo Jin
Lee, Seungmee
Song, Gwonhwa
Lim, Whasun
Park, Sunwoo
Park, Wonhyoung
Abrégé
The present invention relates to a combination regimen of Decitabine and Belotecan for preventing or treating ovarian cancer, and provides a pharmaceutical composition for preventing or treating ovarian cancer, the pharmaceutical composition being characterized by comprising Decitabine or a pharmaceutically acceptable salt or solvate thereof as an active ingredient, wherein the pharmaceutical composition is administered in combination with Belotecan or a pharmaceutically acceptable salt or solvate thereof.
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
DREAMPAC CORPORATION (République de Corée)
Inventeur(s)
Seong, Seung Yong
Kim, Hee Seung
Park, Soo Jin
Abrégé
The present invention relates to an antibody or an antigen-binding fragment thereof comprising a single domain antibody specifically binding to mesothelin, an antibody conjugate comprising same, a pharmaceutical composition for preventing or treating cancer or a tumor, and a composition for diagnosing or monitoring cancer or a tumor. When the antibody or composition comprising same is used, mesothelin-related cancer or tumors can be effectively prevented, treated, or diagnosed.
C07K 16/30 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Choi, Woo Young
Woo, Jae Seung
Park, Geuntae
Abrégé
The present invention relates to a spiking artificial neural network-based nanoelectromechanical neuron device, the device comprising: a first gate electrode receiving a first voltage; a second gate electrode disposed in parallel with the first gate electrode while being spaced apart from the first gate electrode at a predetermined interval, and receiving a second voltage; a drain electrode disposed to be spaced apart from one end of the first gate electrode at a predetermined interval and receiving a spike current signal; a movable beam disposed between the first gate electrode and the second gate electrode and bent in the direction of the drain electrode according to the spike current signal; and an anchor fixing the movable beam to a lower layer. Therefore, the present invention can implement an integrate & fire (IF) neuron by using a nanoelectromechanical (NEM) relay switch, thereby providing high integration and low power compared to existing complementary metal oxide semiconductor (CMOS)-based neurons.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Kyunghan
Lee, Jong Yun
Abrégé
A system for controlling streams according to the present invention comprises: a plurality of client devices that receive, from a media server, a bitrate map including identification information for each of one or more transmission client devices, rating information about a transmission stream transmitted by each of the one or more transmission client devices, and bitrate information about each rating of transmission streams, generate, on the basis of the bitrate map, a selection table composed of combinations of a plurality of reception streams including the ratings of the transmission streams to be received from the transmission client devices and a summed bitrate obtained by summing a bitrate of each of the ratings of the transmission streams, and select the combinations of the reception streams on the basis of a frame delay time; and the media server that receives media encoded from each of the one or more transmission client devices, and transmits the media to one or more reception client devices. The client devices determine the frame delay time on the basis of transmission start time information inserted into a media frame received from the transmission client devices and an arrival time of the media frame.
H04N 21/2662 - Contrôle de la complexité du flux vidéo, p. ex. en mettant à l'échelle la résolution ou le débit binaire du flux vidéo en fonction des capacités du client
H04N 21/2343 - Traitement de flux vidéo élémentaires, p. ex. raccordement de flux vidéo ou transformation de graphes de scènes du flux vidéo codé impliquant des opérations de reformatage de signaux vidéo pour la distribution ou la mise en conformité avec les requêtes des utilisateurs finaux ou les exigences des dispositifs des utilisateurs finaux
H04N 21/647 - Signalisation de contrôle entre des éléments du réseau et serveur ou clientsProcédés réseau pour la distribution vidéo entre serveur et clients, p. ex. contrôle de la qualité du flux vidéo en éliminant des paquets, protection du contenu contre une modification non autorisée dans le réseau ou surveillance de la charge du réseau ou réalisation d'une passerelle entre deux réseaux différents, p. ex. entre réseau IP et réseau sans fil
H04L 7/00 - Dispositions pour synchroniser le récepteur avec l'émetteur
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Hyukjae
Kim, Jongchan
Kim, Gyu Ri
Abrégé
The present invention relates to performance measurement technology performed in a performance measurement device for a very long instruction word (VLIW) processor, the technology comprising the steps of: calculating a scale factor in an operation process based on operation instructions input to the performance measurement device; generating, on the basis of the scale factor, an operation (OP) count value corresponding to the operation instructions; and calculating the energy of the VLIW processor on the basis of the OP count value, wherein the energy may include inter-instruction energy for a plurality of vector operations of the operation instructions.
G06F 11/22 - Détection ou localisation du matériel d'ordinateur défectueux en effectuant des tests pendant les opérations d'attente ou pendant les temps morts, p. ex. essais de mise en route
G06F 9/50 - Allocation de ressources, p. ex. de l'unité centrale de traitement [UCT]
G06F 9/30 - Dispositions pour exécuter des instructions machines, p. ex. décodage d'instructions
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chul-Ho
Park, Sungmin
Abrégé
A modulation doping-based high-mobility semiconductor device according to an embodiment of the present invention comprises: a substrate; a channel layer formed on the substrate; a doped layer stacked on the channel layer and band-aligned with the channel layer to be heterojunctioned with the channel layer; an oxide layer formed on the doped layer and a spacer region of the channel layer; and a first electrode and a second electrode coupled to both end portions of the channel layer, respectively, wherein the oxide layer is formed by oxidizing an initial doped layer and the spacer region of the channel layer before an oxidation process through a monolithic oxidation process.
H10D 30/47 - Transistors FET ayant des canaux à gaz de porteurs de charge de dimension nulle [0D], à une dimension [1D] ou à deux dimensions [2D] ayant des canaux à gaz de porteurs de charge à deux dimensions, p. ex. transistors FET à nanoruban ou transistors à haute mobilité électronique [HEMT]
H10D 62/80 - Corps semi-conducteurs, ou régions de ceux-ci, de dispositifs ayant des barrières de potentiel caractérisés par les matériaux
H10D 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
83.
ACCELERATOR FOR PROCESSING POINT CLOUD DEEP NEURAL NETWORK AND OPERATION METHOD THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jae-Joon
Yoon, Hyunsung
Abrégé
An accelerator for processing a point cloud deep neural network according to an aspect of the present specification includes at least one distance calculator configured to calculate a distance between two points different from each other, wherein the distance calculator includes a first calculation unit, a second calculation unit, and a third calculation unit, and the first calculation unit, the second calculation unit, and the third calculation unit are driven serially to calculate distances on three axes between the two points in a first operation mode, and are driven in parallel to respectively calculate the distances between different pairs of points, in a second operation mode.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
INSTITUTE FOR BASIC SCIENCE (République de Corée)
Inventeur(s)
Kim, Vic Narry
Seo, Jenny
Jung, Soo-Jin
Abrégé
The present disclosure relates to a novel regulatory element for enhancing RNA stability or mRNA translation; ZCCHC2 interacting with the regulatory element; and uses thereof. Being capable of increasing the expression of a target protein, the novel regulatory element for enhancing RNA stability or mRNA translation; and ZCCHC2 interacting with regulatory element according to the present disclosure are applicable in various fields, depending on the uses of the target protein.
C12N 15/67 - Méthodes générales pour favoriser l'expression
C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
C12N 9/12 - Transférases (2.) transférant des groupes contenant du phosphore, p. ex. kinases (2.7)
C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
85.
APPARATUS AND METHOD FOR PREDICTING DIFFUSING CAPACITY USING FLOW-VOLUME CURVE IMAGE BASED ON DEEP LEARNING
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Lee, Changhyun
Lee, Chang-Hoon
Choi, Sunmi
Chung, Wonchul
Abrégé
A diffusing capacity predicting apparatus according to the present disclosure includes a memory including one or more instructions and a processor which executes the one or more instructions stored in the memory. In the memory, first information about a spirometry result of a user, second information which is clinical information, a first machine learning model, and a second machine learning model are recorded. The processor inputs the first information to the first machine learning model to extract a feature related to a lung disease and inputs the extracted feature and the second information to the second machine learning model to predict a diffusing capacity value of the user. Accordingly, the diffusing capacity may be more accurately predicted using the spirometer result and the artificial intelligence model, without using the diffusing capacity test method.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kang, Dae Hee
Shin, Woo Kyoung
Choi, Ji Yeob
Han, Won Shik
Suh, Bong Won
Abrégé
A breast cancer risk prediction device includes a memory storing a risk level prediction program and a processor configured to execute the risk level prediction program, wherein the risk level prediction program calculates a breast cancer occurrence rate by applying questionnaire responses on multiple breast cancer occurrence factors to an occurrence rate calculation model, and outputs a breast cancer occurrence risk level according to the breast cancer occurrence rate, and the occurrence rate calculation model calculates the breast cancer occurrence rate by using an equation for calculating a correlation between the multiple breast cancer occurrence factors and breast cancer occurrence by using the multiple breast cancer occurrence factors for a non-patient cohort who does not have a certain disease.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
G16H 10/20 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des essais ou des questionnaires cliniques électroniques
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
87.
NEUROMORPHIC MEMORY DEVICE AND NEUROMORPHIC SYSTEM USING THE SAME
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Choi, Woo Young
Jeon, Bosung
Abrégé
The present disclosure relates to a neuromorphic memory device and a neuromorphic system using the same. The neuromorphic memory device includes a three-dimensional memory element including NAND cell strings, a bit line that outputs an output signal, forms a first axis of the three-dimensional memory element, and connects NAND cells existing on the same first axis among the NAND cell strings, a word line that receives an input signal, forms a second axis of the three-dimensional memory element, and connects NAND cells existing on the same second axis among the NAND cell strings, and a string selection line that forms a layer of an artificial intelligence neural network, forms a third axis of the three-dimensional memory element, and connects NAND cells existing on the same third axis among the NAND cell strings by intersecting the bit line and the word line.
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Seo, Sanghyuk
Kim, Suhwan
Abrégé
A transceiver connected to a specific channel via a channel connection node, the transceiver includes a transmitter driving a first node and a second node based on an input data signal in a transmission mode, the first node connected to the channel connection node; a receiver receiving a specific channel signal from the channel connection node and providing an output data signal based on the channel signal and an input differentiation signal in a reception mode, the input differentiation signal being generated based on at least one first output differentiation signal; and a switch network circuit connected between the second node and the channel connection node. The switching network circuit has a first circuit in the transmission mode and a second circuit in the reception mode, and provides at least one second output differentiation signal by differentiating the channel.
H04B 1/405 - Circuits utilisant le même oscillateur pour générer à la fois la fréquence de l’émetteur et la fréquence de l’oscillateur local du récepteur avec des canaux discrets multiples
Samsung Electronics Co., Ltd. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hyung Jun
Kang, Yeongkwon
Kwon, Min Sang
Kang, Hyun Bum
Lee, Gae Hwang
Abrégé
Disclosed are a polymer including a structural unit represented by Chemical Formula 1, an organic semiconductor material, and a stretchable polymer thin film and an electronic device including the same.
Disclosed are a polymer including a structural unit represented by Chemical Formula 1, an organic semiconductor material, and a stretchable polymer thin film and an electronic device including the same.
Disclosed are a polymer including a structural unit represented by Chemical Formula 1, an organic semiconductor material, and a stretchable polymer thin film and an electronic device including the same.
The definition of Chemical Formula 1 is as described in the detailed description.
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
DREAMPATH CORP. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Hee Seung
Park, Soo Jin
Kim, Sang Youn
Kim, Taek Min
Kim, Young-Gon
Jang, Boa
Abrégé
The present invention relates to a method for training a model for predicting abdominal surgery information, which is performed by a computing device, the method comprising a step of training an artificial neural network model by using medical image data and masking data labeled with the degree of adhesion between the peritoneum and organs such that, when a medical image is input, the model outputs abdominal surgery-related information of the input medical image.
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
91.
PROXIMITY DATA PROCESSING SYSTEM FOR EXTRA-LARGE MIXTURE-OF-EXPERTS ARTIFICIAL INTELLIGENCE MODEL
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Sim, Jae Woong
Lee, Hyuk Jae
Kim, Tae Hyun
Choi, Kwan Seok
Cho, Young Mok
Abrégé
A mixture-of-experts artificial intelligence model according to the present invention comprises: a CXL control unit that manages a CXL protocol; an NDP control unit that includes a memory mapping register set for communicating with a host; a memory unit composed of a plurality of memory chips that provide a memory capacity to the host; and an NDP core unit that processes MoEs existing in the memory unit, wherein the NDP core unit transmits only hot experts to a GPU accelerator while memory-based calculation is performed on cold experts that exist in the memory unit.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Park, Min Hyuk
Jeong, Hyun Woo
Cho, Yong Hyeon
Abrégé
A semiconductor memory device according to the present disclosure comprises: a substrate; a hafnium zirconium oxide thin film formed by depositing hafnium oxide and zirconium oxide on the substrate; and a second electrode formed by depositing a metal on the hafnium zirconium oxide thin film, wherein an oxygen vacancy is formed in an upper portion of the hafnium zirconium oxide thin film.
H10B 51/30 - Dispositifs de RAM ferro-électrique [FeRAM] comprenant des transistors ferro-électriques de mémoire caractérisés par la région noyau de mémoire
H10D 64/68 - Électrodes ayant un conducteur couplé capacitivement à un semi-conducteur par un isolant, p. ex. électrodes du type métal-isolant-semi-conducteur [MIS] caractérisées par l’isolant, p. ex. par l’isolant de grille
H10D 30/60 - Transistors à effet de champ à grille isolée [IGFET]
H10D 48/00 - Dispositifs individuels non couverts par les groupes
93.
BIOMARKER FOR DIAGNOSIS OR PROGNOSTIC EVALUATION OF PERIODONTITIS
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (République de Corée)
Inventeur(s)
Kim, Jin Man
Lee, Seung Cheol
Cha, Jae Kook
Abrégé
The present disclosure relates to a biomarker for use in the diagnosis or prognostic evaluation of periodontitis, particularly the grade, stage, severity, and/or aggressiveness of periodontitis, and more specifically, the aggressiveness of periodontitis. The present disclosure can be utilized for the early diagnosis and prediction of aggressive periodontitis, aids in developing personalized treatment strategies for each patient with periodontitis, and may greatly improve the clinical management of aggressive periodontitis.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/558 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet utilisant la diffusion ou la migration de l'anticorps ou de l'antigène
94.
SEMICONDUCTOR TRANSISTOR USING MONOLITHIC OXIDIZED METAL SCHOTTKY GATE AND MANUFACTURING METHOD THEREOF
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Chul-Ho
Kim, Yeon Ho
Abrégé
A semiconductor transistor according to an embodiment of the present invention includes: a substrate; a gate layer formed on the substrate; a channel layer formed on the substrate; an insertion layer formed at an interface between the gate layer and the channel layer; and a first electrode and a second electrode coupled to respective ends of the channel layer, wherein the insertion layer is formed on a surface of the gate layer via a monolithic oxidation process.
H10D 30/87 - Transistors FET avec électrodes de grille Schottky, p. ex. transistors FET à métal semiconducteur [MESFET]
H10D 62/13 - Régions semi-conductrices connectées à des électrodes transportant le courant à redresser, amplifier ou commuter, p. ex. régions de source ou de drain
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jae-Joon
Kim, Eunhwan
Abrégé
A memory device includes a plurality of memory cells; a plurality of bit lines respectively connected to the plurality of memory cells; a plurality of separation switches, each being arranged in a central separation region of each bit line for each bit line and separating the central separation region of each bit line in response to a separation signal or connecting separated central separation regions to each other in response to the separation signal; a plurality of sharing switches, each being arranged between adjacent bit lines and separating the adjacent bit lines from each other or connecting the adjacent bit lines to each other in response to a charge sharing signal; and at least one ground switch connected to one end portion of each bit line for each bit line and selectively grounding each bit line.
G11C 11/412 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments électriques utilisant des dispositifs à semi-conducteurs utilisant des transistors formant des cellules avec réaction positive, c.-à-d. des cellules ne nécessitant pas de rafraîchissement ou de régénération de la charge, p. ex. multivibrateur bistable, déclencheur de Schmitt utilisant uniquement des transistors à effet de champ
G11C 5/06 - Dispositions pour interconnecter électriquement des éléments d'emmagasinage
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jae-Joon
Kim, Eunhwan
Abrégé
A memory device includes a plurality of memory cells, each being configured to perform in-memory computing; a storage unit storing data; and an operation circuit including a first capacitor and a second capacitor and configured to adjust a voltage charged to the first capacitor and a voltage charged to the second capacitor according to input data and storage data stored in the storage unit.
G11C 11/412 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments électriques utilisant des dispositifs à semi-conducteurs utilisant des transistors formant des cellules avec réaction positive, c.-à-d. des cellules ne nécessitant pas de rafraîchissement ou de régénération de la charge, p. ex. multivibrateur bistable, déclencheur de Schmitt utilisant uniquement des transistors à effet de champ
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Kwag, Jeehyun
Yeo, Yoonsoo
Abrégé
The present disclosure relates to a Alzheimer's disease diagnosis method based on neural population spike signal synchronization, an Alzheimer's disease diagnosis system, and a Alzheimer's disease diagnosis device based on neural population spike signal synchronization including the system, and it has the advantage of being able to be used for the early diagnosis of Alzheimer's disease by calculating an index for evaluating a degree of neural population signal synchronization of neurons and utilizing the same. In addition, the Alzheimer's disease diagnosis method of the present disclosure is based on the fields of neuroscience, medical imaging and brain disease research, and thus provides information related to dementia by analyzing the neural population spike signal synchronization through a more precise method than the existing method, thereby enabling early diagnosis before Alzheimer's disease symptoms appear, and thus, it can be utilized in various medical and research institutions.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/293 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électroencéphalographie [EEG] invasives
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
98.
POSITIVE ACTIVE MATERIALS, PREPARATION METHODS THEREOF, POSITIVE ELECTRODES, AND RECHARGEABLE LITHIUM BATTERIES
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Yoon, Jaesang
Kong, Youngsun
Kang, Seok Mun
Jun, Dowook
Seong, Wonmo
Hase, Naoyuki
Kang, Kisuk
Ko, Kunhee
Abrégé
A method of preparing a positive electrode active material, a positive electrode and a rechargeable lithium battery are provided. The method of preparing the positive electrode active material includes mixing nickel-manganese-based composite hydroxide and a lithium raw material and subjecting them to primary heat treatment at about 200° C. to about 350° C. and secondary heat treatment at about 800° C. to about 1000° C.
C01G 53/504 - Oxydes complexes contenant du nickel et au moins un autre élément métallique contenant des métaux alcalins, p. ex. LiNiO2 contenant du manganèse du type (MnO2)n-, p. ex. Li(NixMn1-x)O2 ou Li(MyNixMn1-x-y)O2 contenant du lithium et du cobalt avec le rapport molaire du nickel par rapport à tous les métaux autres que les métaux alcalins supérieur ou égal à 0,5, p. ex. Li(MzNixCoyMn1-x-y-z)O2 avec x ≥ 0,5
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
99.
LED DEVICE, METHOD OF MANUFACTURING THE LED DEVICE, AND DISPLAY APPARATUS INCLUDING THE LED DEVICE
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Hwang, Kyungwook
Kang, Sungjin
Yoon, Euijoon
Hwang, Junsik
Kim, Jongmyeong
Oh, Jehong
Ryu, Jungei
Lee, Seungmin
Abrégé
Provided are a light-emitting diode (LED) device, a method of manufacturing the LED device, and a display apparatus including the LED device. The LED device includes a light-emitting layer having a core-shell structure, a passivation layer provided to cover a portion of a top surface of the first semiconductor layer, a first electrode provided on the light-emitting layer, and a second electrode provided under the light-emitting layer. The light-emitting layer includes a first semiconductor layer, an active layer, and a second semiconductor layer. The first electrode is provided to contact the first semiconductor layer, and the second electrode is provided to contact the second semiconductor layer.
H10H 20/821 - Corps caractérisés par leur forme particulière, p. ex. substrats incurvés ou tronqués des régions électroluminescentes, p. ex. jonctions du type non planaire
H01L 25/075 - Ensembles consistant en une pluralité de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide les dispositifs étant tous d'un type prévu dans une seule des sous-classes , , , , ou , p. ex. ensembles de diodes redresseuses les dispositifs n'ayant pas de conteneurs séparés les dispositifs étant d'un type prévu dans le groupe
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Lee, Juhyun
Jeong, Yoonchan
Lee, Eunbi
Abrégé
According to a preferred embodiment of the present invention, a method for converting a reproduction pixel interval and a reproduction wavelength of a hologram pattern comprises the steps of: receiving a first complex hologram pattern; converting the first complex hologram pattern into a second complex hologram pattern through an artificial neural network trained to convert a reproduction pixel interval and a reproduction wavelength; and outputting the second complex hologram pattern.