COMPOSITION FOR ALLEVIATING, TREATING, OR PREVENTING MUSCULAR DISEASES, OR IMPROVING MUSCULAR FUNCTIONS, CONTAINING KOREAN MINT EXTRACT OR TILIANIN AS ACTIVE INGREDIENT
The present disclosure relates to a composition for alleviating, treating or preventing muscular diseases or improving muscular functions, which contains a Korean mint extract or tilianin as an active ingredient. The Korean mint or tilianin according to the present disclosure has effects of increasing the activity of mTOR, which is involved in muscle protein synthesis, and reducing mRNA expression of MuRF-1 and atrogin-1, which are involved in muscle protein degradation. Accordingly, it can be usefully used for prevention, amelioration or treatment of various muscular diseases such as sarcopenia, muscular atrophy, muscular dystrophy, atony, muscular degeneration, myasthenia, cachexia, etc. by increasing muscle mass and improving muscular functions.
A23G 3/48 - Sucreries, confiseries ou massepainProcédés pour leur fabrication caractérisés par la composition contenant des végétaux ou des parties de ceux-ci, p. ex. des fruits, des graines, des extraits
A23G 4/06 - Chewing-gum caractérisé par la composition
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61Q 19/00 - Préparations pour les soins de la peau
2.
COMPOSITION COMPRISING CUDRANIA TRICUSPIDATE AS EFFECTIVE COMPONENT FOR ALLEVIATING, TREATING, OR PREVENTING MUSCULAR DISEASES, OR IMPROVING MUSCULE FUNCTIONS
The present disclosure relates to a composition for preventing and treating a muscular disease, or improving muscular function, which contains Cudrania tricuspidata such as a pulverization product or an extract of Cudrania tricuspidata as an active ingredient. The Cudrania tricuspidata according to the present disclosure such as the pulverization product or extract of Cudrania tricuspidata has an effect of increasing the activity of mTOR, which is involved in muscle protein synthesis, and reducing the mRNA expression of MuRF-1 and atrogin-1, which are involved in muscle protein degradation, increases muscle mass and improves muscular function. Therefore, it may be usefully utilized in the prevention, alleviation or treatment of various muscular diseases such as atony, muscular atrophy, muscular dystrophy, muscle degeneration, muscle weakness, cachexia, sarcopenia, etc.
A61K 36/60 - Moraceae (famille de la mûre), p. ex. arbre à pain ou figuier
A61K 8/9778 - Gnetophyta, p. ex. Ephedraceae [famille du thé mormon]
A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
3.
COMPOSITION FOR IMPROVING, TREATING, OR PREVENTING MUSCLE DISEASE, OR IMPROVING MUSCLE FUNCTION, CONTAINING ROSE HIP AS ACITVE INGREDIENT
The present invention relates to a novel use of rose hip as ground rose hip or a rose hip extract, and to a composition for improving, treating, or preventing muscle disease, or improving muscle function, containing rose hip as an active ingredient. The composition of the present invention has the effect of increasing the activity of mTOR involved in muscle protein synthesis and reducing the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases muscle mass and enhances muscle function such that the composition of the present invention can be helpfully used for preventing, improving, or treating various muscle diseases such as sarcopenia, muscular atrophy, muscular dystrophy, atony, muscle degeneration, myasthenia, cachexia, etc.
A61Q 19/00 - Préparations pour les soins de la peau
A23K 20/00 - Éléments nutritifs accessoires pour produits alimentaires pour animaux
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
4.
COMPOSITION FOR ALLEVIATING, TREATING, OR PREVENTING MUSCULAR DISEASES, OR IMPROVING MUSCULAR FUNCTIONS, CONTAINING KOREAN MINT EXTRACT OR TILIANIN AS ACTIVE INGREDIENT
The present invention relates to a composition for alleviating, treating, or preventing muscular diseases, or improving muscular functions, containing, as an active ingredient, a Korean mint extract or tilianin. Korean mint or tilianin according to the present invention has effects of increasing the activity of mTOR, which is involved in muscle protein synthesis and reducing mRNA expression of MuRF-1 and atrogin-1 which are involved in muscle protein degradation, and increases muscle mass and improves muscle functions, and thus can be effectively used in preventing, treating or alleviating various muscular diseases, such as sarcopenia, muscular atrophy, muscular dystrophy, atony, muscle degeneration, myasthenia and cachexia.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61Q 19/00 - Préparations pour les soins de la peau
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
5.
Composition for preventing, alleviating or treating muscle diseases or improving muscular function
Sargassum fusiforme extract increases the protein expression of p-mTOR, which is a main gene involved in muscle protein synthesis, inhibits the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases the mRNA expression of MyoD and myogenin involved in muscle differentiation, thereby having an effect of remarkably increasing muscular function. In addition, the composition can be safely used without side effects, thereby being usable in medicine, food, cosmetic products, livestock feed, a feed additive and the like.
A61K 31/575 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne d'au moins trois atomes de carbone, p. ex. cholane, cholestane, ergostérol, sitostérol
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61K 36/03 - Phaeophycota ou phaeophyta (algues brunes), p. ex. Fucus
6.
Use of Kaempferia parviflora wall. ex. baker extracts or flavone compound for preventing or treating muscle diseases, or improving muscle function
Kaempferia parviflora Wall. Ex. Baker extracts or flavone compound isolated therefrom according to the present invention reduces protein catabolism in the muscles and increases muscle cell differentiation and anabolism, and is thus effective for preparing pharmaceutical composition for treating muscle diseases and dietary composition for improving muscle function.
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
A61K 36/906 - Zingiberaceae (famille du gingembre)
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
7.
COMPOSITION CONTAINING SQUALENE FOR IMPROVING MUSCLE FUNCTION AND PREVENTING MUSCLE DAMAGE
The present invention relates to a composition for preventing, treating, improving a muscle disease or regenerating muscle damage, containing squalene. More specifically, the squalene of the present invention increases the expression of proteins involved in muscle protein synthesis and muscle mass increase in muscle cells, inhibits an expression of enzymes involved in myoprotein degradation at the level of mRNA, and has an effect of restoring the recovery of damaged muscle quickly. Also, the present invention is a natural product so as to be safely used without side effects, and thus can be used as medicine, food, or cosmetics.
A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
A61Q 19/00 - Préparations pour les soins de la peau
8.
Composition including kirenol or siegesbeckia herba extract for muscle function improvement or exercise ability enhancement
Siegesbeckia herba extract fraction according to the present invention has an effect of remarkably enhancing exercise ability by increasing the protein expression of PGC-1α, which is a major gene concerned with exercise ability. In addition, the present invention is a natural product, and thus is safe for use without side effects and can be used as a medicine or food.
The present invention relates to a composition for preventing or treating muscle diseases or improving muscular function, containing fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract. According to the present invention, fucosterol, Sargassum fulvellum, a Sargassum fulvellum ground product, a Sargassum fulvellum extract, Sargassum fusiforme, a Sargassum fusiforme ground product or a Sargassum fusiforme extract increases the protein expression of p-mTOR, which is a main gene involved in muscle protein synthesis, inhibits the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases the mRNA expression of MyoD and myogenin involved in muscle differentiation, thereby having an effect of remarkably increasing muscular function. In addition, since the composition of the present invention is a natural product, the composition can be safely used without side effects, thereby being usable in medicine, food, cosmetic products, livestock feed, a feed additive and the like.
A61K 31/56 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes
A61K 31/575 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne d'au moins trois atomes de carbone, p. ex. cholane, cholestane, ergostérol, sitostérol
A61K 36/03 - Phaeophycota ou phaeophyta (algues brunes), p. ex. Fucus
10.
Boesenbergia pandurata for enhancing muscle mass growth, fighting fatigue, and enhancing exercise performance
Boesenbergia pandurata of the present invention may be used without side effect and has the effect of increasing the expression of PPAR-δ in muscles to increase muscle mass, promoting recovery from fatigue and increase mobility, thereby improving exercise performance.
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
A61K 36/906 - Zingiberaceae (famille du gingembre)
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
The present invention relates to a pharmaceutical composition containing flavone compound as an active ingredient for treating obesity, and more specifically to a pharmaceutical composition for preventing or treating obesity and a dietary composition for preventing or reducing obesity containing 5,7-dimethoxyflavone or 5,7,4′-trimethoxyflavone. The compound according to the present invention inhibits adipogenesis, and reduces expression of the key transcription factors (SREBP1c and C/EBP) related to lipogenesis and of enzyme proteins (FAS and ACC) related to adipogenesis, and thus is effective in preventing or treating obesity.
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
12.
Use of kaempferia parviflora wall. ex. baker extracts or flavone compound for preventing or treating muscle diseases, or improving muscle function
Kaempferia parviflora Wall. Ex. Baker extracts or flavone compound isolated therefrom according to the present invention reduces protein catabolism in the muscles and increases muscle cell differentiation and anabolism, and is thus effective for preparing pharmaceutical composition for treating muscle diseases and dietary composition for improving muscle function.
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
A61K 36/906 - Zingiberaceae (famille du gingembre)
A61K 31/35 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
13.
Boesenbergia pandurata for promoting muscle mass growth, fighting fatigue, and enhancing exercise performance capability
Boesenbergia pandurata of the present invention may be used without side effect and has the effect of increasing the expression of PPAR-δ in muscles to increase muscle mass, promoting recovery from fatigue and increase mobility, thereby improving exercise performance.
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
A61K 36/906 - Zingiberaceae (famille du gingembre)
A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme-1 (MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.
Boesenbergia pandurata extract to prepare a reagent for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes.
The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.
A61K 31/36 - Composés contenant des groupes méthylènedioxyphényle, p. ex. sésamine
A61K 31/34 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à cinq chaînons avec un oxygène comme seul hétéro-atome d'un cycle, p. ex. isosorbide
A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
17.
Method and composition for treating acne using lignan compounds
The present invention relates to a method and composition for treating acne using lignan compounds represented by Formula 1. More particularly, the invention relates to an antibacterial composition against acne-causing bacteria, containing lignan compounds represented by Formula 1, as well as a method for treating acne using the same. The lignan compounds represented by Formula 1 are excellent not only in the antibacterial activity of inhibiting the growth of acne-causing bacteria, but also in thermal stability. Accordingly, the lignan compounds may be useful as antibacterial agents against the acne-causing bacteria, and acne treatment agents.
A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés
A61K 31/36 - Composés contenant des groupes méthylènedioxyphényle, p. ex. sésamine
A61Q 19/00 - Préparations pour les soins de la peau