C01B 6/21 - Préparation de borohydrures des métaux alcalins, des métaux alcalino-terreux, du magnésium ou du bérylliumLeurs complexes d'addition, p. ex. LiBH4.2N2H4, NaB2H7
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kong, Gu
Kuchukulla, Ratnakar Reddy
Kim, Su Min
Moon, So Jeong
Hur, Woo Young
Hwang, In Jeong
Abrégé
The present invention relates to a heteroaryl derivative, a stereoisomer thereof, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The heteroaryl derivative of the present invention exhibits high inhibitory activity against overexpressed HER2, and thus, a pharmaceutical composition containing the same as an active ingredient can be usefully used for preventing or treating HER-2 positive cancer.
C07D 473/16 - Composés hétérocycliques contenant des systèmes cycliques purine avec des atomes d'oxygène, de soufre ou d'azote liés directement en positions 2 et 6 deux atomes d'azote
C07D 473/40 - Composés hétérocycliques contenant des systèmes cycliques purine avec des atomes d'halogènes ou des radicaux perhalogénoalkyles liés directement en position 2 ou 6
3.
METHOD OF MANUFACTURING DEHYDROGENATION CATALYST USING ATOMIC LAYER DEPOSITION
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Yong Min
Nam, Suk Woo
Sohn, Hyuntae
Jeong, Hyangsoo
Yoon, Sung Pil
Choi, Sun-Hee
Lee, Yu-Jin
Abrégé
Disclosed herein is a method of manufacturing a dehydrogenation catalyst, the method includes: forming a functional oxide coating layer on a surface of a support with a first atomic layer deposition; and depositing metal particles on the surface of the support on which the functional oxide coating layer is formed, with a second atomic layer deposition.
C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING INFLAMMATORY DISEASES COMPRISING EXTRACELLULAR VESICLES DERIVED FROM ROSEBURIA SPP. OR BIFIDOBACTERIUM SPP.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Choi, Ki Young
Cha, Kwang-Hyun
Han, Hwa Seung
Park, Jin Soo
Song, Dae-Geun
Kim, Myung Suk
Kwon, Hak Cheol
Abrégé
Provided is a method for preventing, ameliorating, or treating inflammatory diseases by administering a composition containing extracellular vesicles (EVs) derived from Roseburia spp. strains and/or Bifidobacterium spp. strains, wherein the EVs exhibits effectiveness in improving inflammatory bowel disease (IBD), and additionally, all EVs derived from congeneric strains corresponding to Roseburia spp. strains or Bifidobacterium spp. strains. have been confirmed to exhibit strong anti-inflammatory effect, and the strains and EVs derived therefrom can be provided as a composition for preventing, ameliorating, or treating a variety of inflammatory diseases.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Ryu, Ju Hee
Kwon, Ick Chan
Hong, Seung Taek
Seong, Yejin
Abrégé
The present invention relates to a composition for predicting cetuximab responsiveness in cancer, and more specifically to a composition for predicting cetuximab responsiveness, comprising a complex (Cetux-probe) having a fluorophore and a quencher bound to both sides of a peptide cleaved by a lysosomal enzyme, and having cetuximab conjugated to the C-terminus of the peptide. The Cetux-probe of the present invention operates in the same manner as the therapeutic mechanism of cetuximab, and thus the therapeutic effect and responsiveness of cetuximab may be quickly and accurately predicted. Cetux-probe activated fluorescence may be used to measure EGFR degradation, and a strong linear correlation between the Cetux-probe activated fluorescence and the cytotoxicity of cetuximab was observed in colorectal cancer cells and tumor-bearing mice. In addition, the predictive ability of the Cetux-probe activated fluorescence was confirmed to be much higher than that of EGFR expression or KRAS mutation status, and thus the Cetux-probe of the present invention may be usefully employed for predicting a response to cetuximab therapy by assessing EGFR degradation.
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
6.
LIPID NANOPARTICLES COMPRISING TUMOR-TARGETING LIGANDS, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Yelee
Kim, Sun Hwa
Yang, Yoosoo
Jang, Yeongji
Abrégé
Disclosed in the present application are: lipid nanoparticles comprising a tumor-targeting ligand; a method for preparing same; and a pharmaceutical composition for preventing or treating tumors, comprising same. The lipid nanoparticles include a nucleic acid, an ionizable lipid, a phospholipid, a sterol, a first conjugate, and a second conjugate in which a tumor-targeting ligand is linked. The first conjugate is a conjugate of a phospholipid and a polymer, and the second conjugate is a conjugate in which a tumor-targeting ligands is linked to the first conjugate. The lipid nanoparticles have a high targeting ability to solid tumors expressing PD-L1.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Dong Ki
Lee, Ung
Oh, Hyung-Suk
Min, Byoung Koun
Won, Dahye
Koh, Jai Hyun
Lee, Woong Hee
Woo, Jongin
Moon, Byeong Cheul
Abrégé
A catalyst electrode for production of 2,5-furandicarboxylic acid according to an embodiment of the present invention includes: a first metal substrate; and a second metal hydroxide coating layer located on a surface of the first metal substrate, wherein the first metal substrate includes one or more micro-sized first metal particles on the surface thereof, and the second metal hydroxide coating layer may be located on a surface of the first metal particles.
C25B 3/07 - Composés contenant au moins un atome d’oxygène
C25B 11/037 - Électrodes constituées de particules
C25B 11/091 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques
8.
HYBRID PERC SOLAR CELL AND MANUFACTURING METHOD THEREFOR, AND TANDEM SOLAR CELL COMPRISING SAME AND MANUFACTURING METHOD THEREFOR
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Inho
Lee, Doh-Kwon
Kim, Young Hyun
Choi, Dongjin
Lee, Haram
Hwang, Gyu Weon
Kim, Jaewook
Abrégé
The objective of the present invention is to provide a hybrid PERC solar cell and a manufacturing method therefor, and a tandem solar cell comprising same and a manufacturing method therefor, the hybrid PERC solar cell being suitable for a monolithic tandem solar cell in which a perovskite thin-film solar cell is stacked and bonded on a silicon solar cell. In order to accomplish the objective, the present invention comprises: a silicon wafer; a rear passivation layer formed on the rear surface of the silicon wafer; a front passivation layer formed on the front surface of the silicon wafer; an emitter layer formed on the front passivation layer; a TCO layer formed on the emitter layer; and a rear electrode layer formed under the rear passivation layer, and electrically connected to the silicon wafer through an opening.
H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
H10K 30/15 - Dispositifs à semi-conducteurs sensibilisés à large bande interdite, p. ex. TiO2sensibilisé aux colorants
H10K 39/15 - Modules photovoltaïques [PV] organiquesRéseaux de cellules PV organiques simples comprenant à la fois des cellules PV organiques et des cellules PV inorganiques
9.
STEEL REINFORCEMENT AND METHOD FOR MANUFACTURING THE SAME
Korea University Research and Business Foundation (République de Corée)
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Chung, Jun Ho
Kim, Tae Hyung
Abrégé
Provided is a steel reinforcement including an amount of 0.07 to 0.43 wt % of carbon (C), an amount of 0.5 to 2.0 wt % of manganese (Mn), an amount of 0.05 to 0.5 wt % of silicon (Si), an amount greater than 0 and less than or equal to 0.5 wt % of chromium (Cr), an amount greater than 0 and less than or equal to 4.5 wt % of copper (Cu), an amount greater than 0 and less than or equal to 0.003 wt % of boron (B), an amount greater than 0 and less than or equal to 0.25 wt % of vanadium (V), an amount greater than 0 and less than or equal to 0.012 wt % of nitrogen (N), an amount greater than 0 and less than or equal to 0.03 wt % of phosphorus (P), an amount greater than 0 and less than or equal to 0.03 wt % of sulfur(S), an amount of 0.01 to 0.5 wt % of the sum of one or more of nickel (Ni), niobium (Nb) and titanium (Ti), the balance of iron (Fe), and other inevitable impurities. A final microstructure includes ferrite, bainite, pearlite, retained austenite, and precipitates comprising copper.
C22C 38/32 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du bore
C21D 8/02 - Modification des propriétés physiques par déformation en combinaison avec, ou suivie par, un traitement thermique pendant la fabrication de produits plats ou de bandes
C21D 8/06 - Modification des propriétés physiques par déformation en combinaison avec, ou suivie par, un traitement thermique pendant la fabrication de barres ou de fils
C22C 38/00 - Alliages ferreux, p. ex. aciers alliés
C22C 38/02 - Alliages ferreux, p. ex. aciers alliés contenant du silicium
C22C 38/04 - Alliages ferreux, p. ex. aciers alliés contenant du manganèse
C22C 38/20 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du cuivre
C22C 38/24 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du vanadium
C22C 38/26 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du niobium ou du tantale
C22C 38/28 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du titane ou du zirconium
C22C 38/40 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du nickel
10.
LIGHT-BASED DIAGNOSTIC AND THERAPEUTIC DEVICE AND OPERATING METHOD FOR LIGHT-BASED DIAGNOSTIC AND THERAPEUTIC DEVICE
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (République de Corée)
Inventeur(s)
Yang, Sung Wook
Kim, Jin
Choi, Myung Hwan
Chong, Kyu Ha
Abrégé
Disclosed are a light-based diagnostic and therapeutic device and an operating method for the light-based diagnostic and therapeutic device. The operating method for the light-based diagnostic and therapeutic device may comprise the operations of: acquiring local images over time through a camera of the light-based diagnostic and therapeutic device; extracting image feature points from the local images; generating a lesion map including a lesion area of a user by combining the local images on the basis of the extracted image feature points; and generating a cumulative light irradiation map indicating cumulative information of therapeutic light output to the lesion area on the basis of the lesion map and position information of a light stimulation unit of the light-based diagnostic and therapeutic device over time.
POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Chang, Young Tae
Kim, Youn Kyung
Abrégé
The present invention relates to a compound sensing clathrin-mediated endocytosis, a fluorescent probe comprising same, and a sensor and a sensing method. The compound according to the present invention forms a micelle in a quenching state, and when in contact with a cell, the compound is transported into the cell through clathrin-mediated endocytosis and becomes fluorescent. Accordingly, the compound can be used to sense clathrin-mediated endocytosis or stain and label cells in which clathrin-mediated endocytosis takes place. The compound used in the present invention is particularly excellent in that the compound is stably transported via endocytosis into cells, such as live neurons or embryonic stem cells, within a relatively short time and maintains fluorescence for a long time at high fluorescence intensity. In addition, not only somatic cells but also cell-membranes and spikes can be stained.
G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
12.
ANODE ACTIVE MATERIAL AND ITS MANUFACTURING METHOD, LITHIUM ION BATTERY AND ALL-SOLID-STATE LITHIUM THIN-FILM BATTERY USING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Choi, Ji-Won
Yim, Haena
Hwang, Yaelim
Kang, Chong Yun
Baek, Seung Hyub
Kim, Seong Keun
Song, Hyun-Cheol
Yoon, Jungho
Jang, Ji-Soo
Hur, Sunghoon
Abrégé
The present invention relates to a transparent anode active material having excellent light transmittance and electrical conductivity characteristics and a manufacturing method thereof, and a lithium ion battery and an all-solid-state lithium thin-film battery based on the same and having excellent charge/discharge capacity and charge/discharge rate, wherein the transparent anode active material according to the present invention is characterized by comprising a material of the following Chemical Formula 1: AgxSiOyN wherein x is 0
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
C01B 21/082 - Composés contenant de l'azote et des non-métaux
H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
13.
APPARATUS FOR LIGHT-BASED DIAGNOSTIC TREATMENT AND OPERATING METHOD THEREOF
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (République de Corée)
Inventeur(s)
Yang, Sungwook
Kim, Jin
Choi, Myunghwan
Chong, Kyuha
Abrégé
A light-based diagnostic treatment apparatus and an operating method of a light-based diagnostic treatment apparatus are provided. The operating method of a light-based diagnostic treatment apparatus includes obtaining local images over time through a camera of the light-based diagnostic treatment apparatus, extracting an image feature point from the local images, generating a lesion map including a lesion area of a user by combining the local images based on the extracted image feature point, and generating a cumulative light irradiation map indicating accumulation information of therapeutic light output to the lesion area based on the lesion map and position information of an optical stimulation unit of the light-based diagnostic treatment apparatus.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Son, Hae Jung
Jin, Hyunjung
Kim, Kyuyeon
Rhee, Jinhyeong
Kim, Kyeongmin
Shin, Eul-Yong
Yu, Hyeonggeun
Kim, Jai Kyeong
Kim, Jin Young
Abrégé
The present disclosure relates to a network polymer and a manufacturing method thereof. An object of one aspect of the present invention is to provide a network polymer that can recover and recycle a key monomer from a polymer with excellent decomposability and is formed therefrom to have excellent mechanical and electrical properties, and a method of manufacturing the same. The network polymer according to one embodiment of the present invention is recycled from a polymer with excellent decomposability and thus is eco-friendly, and exhibits the effect of having excellent mechanical and electrical properties.
C08J 11/20 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec une substance organique par traitement avec des hydrocarbures ou des hydrocarbures halogénés
C08J 11/14 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec de la vapeur ou de l'eau
H01L 31/072 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PN à hétérojonction
H10K 30/30 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des hétérojonctions de masse, p. ex. des réseaux interpénétrés de domaines de matériaux donneurs et accepteurs
15.
SILICON-BASED ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, AND SECONDARY BATTERY ANODE MATERIAL USING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Hong, Ji Hyun
Lee, Min Ah
Choi, Jin Kwan
Jung, Hun Gi
Kim, Dong Ik
Abrégé
The present invention relates to a pre-lithiation method for a silicon-based active material, and a silicon-based active material pre-lithiated thereby, the method comprising the steps of: (S1) immersing a silicon-based active material in a pre-lithiation solution comprising an organic solvent and a lithium-hydrocarbon molecular complex; (S2) washing same with the solvent and drying same, thereby obtaining a powder; and (S3) heat-treating the powder at a temperature of 400-800°C under an inert gas atmosphere.
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
H01M 4/133 - Électrodes à base de matériau carboné, p. ex. composés d'intercalation du graphite ou CFx
H01M 4/134 - Électrodes à base de métaux, de Si ou d'alliages
H01M 4/136 - Électrodes à base de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFy
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Jeong, Youngdo
Lee, Kwan Hyi
Kim, Hojun
Kang, Seok Ho
Yoon, Sung-Goo
Shim, Ji Sung
Noh, Tae Il
Abrégé
The present invention provides a linker having a net or cage structure, the structure of which is modified by a biomarker operating under a biphasic system consisting of a water layer and an oil layer. The linker is structurally modified in the presence of a biomarker to release a phase-shift probe contained therein, and the released phase-shift probe can be detected in the oil layer. In detection of the biomarker under the biphasic system using the linker of the present invention, the recognition of a target and the detection of a signal by the recognition are separated into the water layer and the oil layer, and thus the target can be detected with high accuracy. In addition, the system of the present invention does not require pretreatment of a sample, and thus can rapidly and accurately detect a quantitative biomarker with high sensitivity without expensive equipment and expertise required for pretreatment of a clinical specimen.
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
G01N 21/84 - Systèmes spécialement adaptés à des applications particulières
17.
SILICON-BASED ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY AND SECONDARY BATTERY ANODE MATERIAL USING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Hong, Jihyun
Lee, Minah
Choi, Jinkwan
Jung, Hun-Gi
Kim, Dong-Ik
Abrégé
Provided are a prelithiation method of a silicon-based active material, the prelithiation method including step S1 of immersing the silicon-based active material in a prelithiation solution including an organic solvent and a lithium-hydrocarbon molecule complex, step S2 of obtaining a powder by washing the silicon-based active material with the organic solvent and drying the silicon-based active material, and step S3 of performing a heat treatment on the powder at a temperature of 400° C. to 800° C. in an inert gas atmosphere, and a silicon-based active material prelithiated by the method.
H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p. ex. LiTi2O4 ou LiTi2OxFy
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
18.
POLYDOPAMINE COMPOSITE MATERIAL AND MANUFACTURING METHOD THEREOF
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Moon, Myoung-Woon
Kim, Seong Jin
Lee, Young A
Oh, Chan Young
Park, Sang-Jin
Abrégé
Provided is a polydopamine composite material according to the concept of the present invention, wherein the polydopamine composite material includes a substrate with first nano-protrusions formed on a surface thereof, and a polydopamine layer on the surface of the substrate. The polydopamine layer includes second nano-protrusions protruding in a direction perpendicular to the surface of the substrate.
C09D 179/04 - Polycondensats possédant des hétérocycles contenant de l'azote dans la chaîne principalePolyhydrazidesPolyamide-acides ou précurseurs similaires de polyimides
19.
FIBER COMPOSITE STRUCTURE AND MANUFACTURING METHOD THEREOF
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Moon, Myoung-Woon
Kim, Seong Jin
Lee, Young A
Oh, Chan Young
Lee, Cho Hee
Abrégé
Provided is a fiber composite structure including a plurality of twisted fiber bundles, wherein each of the fiber bundles includes a plurality of fiber strands, an adhesive coated on the fiber strands, and a functional particle interposed between the fiber strands. The functional particle includes a material different from that of the fiber strands. The adhesive includes polydopamine.
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Kim, Gwan Sik
Song, Kyong Hwa
Yun, Deok Woo
Jeong, Hyeon Su
Kim, Seung Min
Kim, Nam Dong
Lee, Sung Ju
Abrégé
The present disclosure describes to a method embodiment for preparing a carbon nanotube composite that includes performing a first ultrasonic treatment on a first mixture containing a carbon nanotube (CNT) fiber and an acid to form a carbon nanotube fiber swollen body, and performing a second ultrasonic treatment on a second mixture containing the carbon nanotube fiber swollen body, an aromatic monomer, and an initiator to form a carbon nanotube composite including a surface coated with an aromatic monomer-derived conductive polymer, and an embodiment of the carbon nanotube composite prepared therefrom.
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Kim, Dong Gu
Lee, Jang Hyeon
Kwon, Dae Sung
Kim, Hyun Soo
Yoo, Il Seon
Lee, Byung Chul
Cho, Seong Hun
Baek, Seung Hyub
Kim, Min Seok
Jung, Soo Young
Abrégé
A non-contact interface device for a vehicle and a method for controlling the same, may display an operation system menu for a driver and passengers to operate various kinds of devices of the vehicle as a hologram, enable a user to operate the displayed operation system menu in a non-contact manner by use of the user's finger or the like, and provide the user with a tactile feedback for a non-contact operation, so that the user can recognize whether to have operated the menu.
B60K 35/00 - Instruments spécialement adaptés aux véhiculesAgencement d’instruments dans ou sur des véhicules
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
G06F 3/043 - Numériseurs, p. ex. pour des écrans ou des pavés tactiles, caractérisés par les moyens de transduction utilisant la propagation d'ondes acoustiques
G06F 3/0482 - Interaction avec des listes d’éléments sélectionnables, p. ex. des menus
G06V 20/56 - Contexte ou environnement de l’image à l’extérieur d’un véhicule à partir de capteurs embarqués
G06V 40/10 - Corps d’êtres humains ou d’animaux, p. ex. occupants de véhicules automobiles ou piétonsParties du corps, p. ex. mains
G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes
22.
Stretchable substrate having improved thickness deformation uniformity through control of spatial crosslinking degree and method of manufacturing the same
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Chung, Seungjun
Choi, Jun Chan
Jeong, Hoon Yeub
Lee, Phillip
Son, Jeong Gon
Kim, Heesuk
Abrégé
Provided is a method of manufacturing a stretchable substrate having improved thickness deformation uniformity through control of a spatial crosslinking degree according to various embodiments of the present disclosure to implement the above object. The method includes forming a substrate part of an elastic material, forming an auxetic including a plurality of unit structures on the substrate part, and forming a fixing part on the substrate part on which the auxetic is formed, wherein the fixing part has a different vertical crosslinking density at each position.
B32B 3/12 - Produits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche discontinue, c.-à-d. soit continue et percée de trous, soit réellement constituée d'éléments individuels caractérisés par une couche d'alvéoles disposées régulièrement, soit formant corps unique dans un tout, soit structurées individuellement ou par assemblage de bandes indépendantes, p. ex. structures en nids d'abeilles
B32B 37/14 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par les propriétés des couches
23.
METHOD FOR CONTACT VERIFICATION BASED ON RECEIVED SIGNAL SIMILARITY AND APPARATUS THEREOF
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Taikjin
Kyung, Hankyeol
Kim, Chansoo
Kim, Sangkyung
Shin, Beomju
Kim, Taehun
Abrégé
The present disclosure relates to a contact verification technology based on signal similarity, and an apparatus of contact verification receives and stores spatiotemporal signal information capable of specifying time and space from a plurality of user equipments (UEs), extract the spatiotemporal signal information of a specific user among the stored spatiotemporal signal information, configure the extracted spatiotemporal signal information of the specific user as reference spatiotemporal signal information, and compare similarity between the reference spatiotemporal signal information and the other stored spatiotemporal signal information, and determine whether or not there is contact between the specific user and another user based on the similarity.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kong, Gu
Hur, Wooyoung
Cha, Hea Ry
Moon, Sojung
Kye, Younghyeon
Kuchukulla, Ratnakar Reddy
Hwang, Injeong
Abrégé
The present invention relates to: a heteroaryl derivative, a stereoisomer thereof, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; a method for preparing same; and a pharmaceutical composition containing same as an active ingredient for the prevention or treatment of cancer, wherein the heteroaryl derivative of the present invention can be usefully employed for the prevention or treatment of HER2-positive carcinoma.
STRETCHABLE SUBSTRATE HAVING IMPROVED STRETCHING DEFORMATION UNIFORMITY THROUGH CONTROL OF SPATIAL CROSSLINKING DEGREE AND METHOD OF MANUFACTURING THE SAME
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Chung, Seungjun
Choi, Jun Chan
Jeong, Hoon Yeub
Son, Jeong Gon
Kim, Heesuk
Lee, Phillip
Abrégé
Provided is a method of manufacturing a stretchable substrate having improved stretching deformation uniformity through control of a spatial crosslinking degree according to various embodiments of the present disclosure to implement the above object. The method includes forming a substrate part of an elastic material, forming an auxetic including a plurality of unit structures on the substrate part, and forming a fixing part on the substrate part on which the auxetic is formed, wherein the fixing part has a different crosslinking density in each region.
B32B 3/12 - Produits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche discontinue, c.-à-d. soit continue et percée de trous, soit réellement constituée d'éléments individuels caractérisés par une couche d'alvéoles disposées régulièrement, soit formant corps unique dans un tout, soit structurées individuellement ou par assemblage de bandes indépendantes, p. ex. structures en nids d'abeilles
B32B 37/14 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par les propriétés des couches
26.
METHOD AND APPARATUS FOR IDENTIFYING CONTACT ON BASIS OF SIGNAL SIMILARITY
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Taikjin
Kyung, Hankyeol
Kim, Chansoo
Kim, Sangkyung
Shin, Beomju
Kim, Taehun
Abrégé
The present invention relates to a technology for identifying a contact on the basis of a signal similarity. An apparatus for identifying a contact: receives space-time signal information capable of specifying time and space from a plurality of user terminals and stores the received space-time signal information; extracts space-time signal information of a specific user from the stored space-time signal information; configures the extracted space-time signal information of the specific user as reference space-time signal information; compares a similarity between the reference space-time signal information and the stored other space-time signal information; and determines whether the specific user and another user are in contact with each other on the basis of the similarity.
G16H 50/80 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la détection, le suivi ou la modélisation d’épidémies ou des pandémies, p. ex. de la grippe
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
H04W 4/029 - Services de gestion ou de suivi basés sur la localisation
H04W 4/80 - Services utilisant la communication de courte portée, p. ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
H04W 84/12 - Réseaux locaux sans fil [WLAN Wireless Local Area Network]
27.
MULTILAYER REINFORCED COMPOSITE ELECTROLYTE MEMBRANE AND METHOD FOR MANUFACTURING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Jin Young
Lim, Youngjoon
Kwon, Taehyun
Min, Byeong-Jo
Seo, Bora
Park, Hee-Young
Lee, So Young
Park, Hyun Seo
Yoo, Sung Jong
Kim, Hyoung-Juhn
Jang, Jong Hyun
Abrégé
The present disclosure relates to a multilayer reinforced composite electrolyte membrane and a method for manufacturing the same. The multilayer reinforced composite electrolyte membrane according to the present disclosure has sufficient mechanical properties and improved membrane resistance at the same time since a porous support is impregnated in an ionomer and it is stacked in a multilayer structure. Furthermore, since the composite electrolyte membrane has no wrinkles and cracks due to excellent dimensional stability, it can improve the electrochemical properties of batteries.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
DANA-FARBER CANCER INSTITUTE, INC. (USA)
Inventeur(s)
Ryu, Ju Hee
Kwon, Ick Chan
Ko, Youngji
Roberts, Thomas M.
Zhao, Jean J.
Ding, Liya
Abrégé
Provided is BRCA-specific siRNA for enhancing the sensitivity of cancer cells to PARP inhibitors. According to the present disclosure, the siRNA can induce cancer cell death together with the PARP inhibitors in patients with wild-type BRCA genes with a low therapeutic effect of the PARP inhibitors, and the fusion protein-siRNA complex for siRNA delivery is up-taken into cells via CD47, and thus more specifically delivered to cancer cells while up-taken with high efficiency, thereby maximizing a desired cell death effect.
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
A61K 47/65 - Séquences de liaison, liants ou bras-espaceurs peptidiques, p. ex. séquences de liaison peptidiques vulnérable aux protéases
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Yang, Yoosoo
Kim, Sun Hwa
Cho, Haeun
Jang, Yeongji
Han, Geonhee
Kim, Hyosuk
Abrégé
The present invention relates to a composition for improving intestinal health and function comprising: a milk-derived exosomes; and a therapeutic agent, wherein the therapeutic agent is DNA, RNA, or a small molecule, and the therapeutic agent is positioned and encapsulated in spaces inside the exosomes. In addition, provided is a method for manufacturing a composition for improving intestinal health and function, the method comprising the steps of: (a) isolating exosomes from milk; (b) forming micropores on the surfaces of the exosomes by subjecting the separated exosomes to electroporation; (c) mixing the exosomes that have undergone electroporation in step (b) with a therapeutic agent; and (d) removing therapeutic agent which has not been encapsulated inside the exosomes.
A61K 31/7105 - Acides ribonucléiques naturels, c.-à-d. contenant uniquement des riboses liés à l'adénine, la guanine, la cytosine ou l'uracile et ayant des liaisons 3'-5' phosphodiester
A61K 31/711 - Acides désoxyribonucléiques naturels, c.-à-d. contenant uniquement des 2'-désoxyriboses liés à l'adénine, la guanine, la cytosine ou la thymine et ayant des liaisons 3'-5' phosphodiester
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
ARTIFICIAL INTELLIGENCE SYSTEM FOR GENERATING ACTION TENDENCY CONSIDERING EMOTION AND MOOD ACCORDING TO EXTERNAL INFORMATION RECOGNITION AND METHOD THEREOF
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Park, Sungkee
Hwang, Junggyu
Abrégé
An artificial intelligence system and a method for generating action tendency by considering emotion and mood according to recognition of external information include generating primary emotion and mood based on external information of the artificial intelligence system and a preset nature data, generating secondary emotion based on the generated mood, and generating action tendency for suggesting a direction of action decision of the artificial intelligence system based on the generated secondary emotion, and accordingly, an artificial intelligence system capable of smooth and natural interaction with people may be provided.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Chan
Lee, Yu-Jin
Kirk, Jaewon
Jeong, Hyangsoo
Kim, Yong Min
Sohn, Hyuntae
Nam, Suk Woo
Abrégé
Disclosed herein are a catalyst for low-temperature carbon monoxide purification, a method for manufacturing the same, and a method for purifying carbon monoxide using the same. The catalyst comprises a metal oxide carrier; a transition metal oxide primarily supported on the carrier, and ruthenium secondarily supported on a carrier carrying the transition metal oxide. The catalyst provides an effect capable of purifying carbon monoxide contained in a hydrogen gas at a low temperature.
B01J 23/00 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe
B01J 23/46 - Ruthénium, rhodium, osmium ou iridium
C01B 3/58 - Séparation de l'hydrogène ou des gaz contenant de l'hydrogène à partir de mélanges gazeux, p. ex. purification par contact avec des solidesRégénération des solides usés comportant une réaction catalytique
32.
METHOD AND APPARATUS FOR AUTOMATICALLY GENERATING DRUM PLAY MOTION OF ROBOT
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Cho, Jungsoo
Yim, Sehyuk
Abrégé
A method of generating a drum play motion of a robot includes generating a plurality of rhythms of a melody, assigning each of a plurality of notes forming a rhythm of each part to one of the right hand and the left hand of the robot, scheduling swing time of each of the right hand and the left hand to which each note is assigned, and generating a trajectory of each of a plurality of joints of the robot for playing the rhythm of each part based on the swing time of each of the right hand and the left hand, and by controlling a motion of each of the plurality of joints according to the trajectory of each of the plurality of joints generated in this way, creative drum play of a humanoid robot may be done when only a melody is input.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Park, Ki Duk
Park, Jong Hyun
Choi, Ji Won
Lee, Elijah
Lee, Changjoon
Won, Woojin
Mridula, Bhalla
Abrégé
The present invention provides: a pharmaceutical composition for preventing or treating aging-related diseases or disorders, comprising an aminoaromatic compound or a pharmaceutically acceptable salt thereof as an active ingredient; a composition for delaying aging or extending lifespan; and a health functional food composition for preventing or alleviating aging-related diseases.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Pae, Ae Nim
Kim, Yun Kyung
Lim, Sung Su
Lim, Sang Min
Lee, Ha Eun
Jeong, Da Yeon
Lee, Chang Yong
Gotina, Lizaveta
Kang, Dong Min
Lukianenko, Nataliia
Kim, Kyu Hyeon
Abdildinova, Aizhan
Abrégé
The present invention relates to a novel saturated heterocycle-substituted heteroaryl-carbonohydrazonoyl dicyanide compound or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition comprising same as an active ingredient for preventing or treating neurological diseases. The saturated heterocycle-substituted heteroaryl-carbonohydrazonoyl dicyanide compound of the present invention inhibits the aggregation or hyperphosphorylation of tau protein and/or TDP-43, and thus can be used for preventing and treating neurological diseases including tauopathy and TDP-43 proteinopathy.
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61K 31/5386 - 1,4-Oxazines, p. ex. morpholine condensées en spiro ou formant une partie de systèmes cycliques pontés
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
C07D 263/58 - BenzoxazolesBenzoxazoles hydrogénés avec des hétéro-atomes ou avec des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement en position 2
C07D 235/30 - Atomes d'azote ne faisant pas partie d'un radical nitro
C07D 413/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Han, Sang Soo
Kim, Donghun
Yoo, Hyuk Jun
Kim, Nayeon
Lee, Seung Yong
Abrégé
Provided is a modular experiment automation system including a main computer, a material synthesis module, and a material analysis module. The main computer interacts with a material synthesis module and a material analysis module. Upon a start request, it provides synthesis instructions for a target material. Once synthesis is complete, it instructs the analysis module to analyze the material. Based on the analysis results, if the error exceeds a threshold, it generates a new synthesis condition and re-initiates synthesis.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes Manipulation de matériaux à cet effet
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Myung Suk
Jung, Sang Hoon
Ko, Hye Jin
Le, Tam Thi
Abrégé
The present invention relates to a composition for preventing or treating muscle disease comprising an extract of Aralia Elata. The Aralia Elata extract of the present invention has the effect of improving grip strength, increasing muscle weight, and improving exercise performance.
A61K 31/085 - Éthers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/216 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides ayant des cycles aromatiques, p. ex. bénactizyne, clofibrate
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
37.
NOVEL FLUORESCENT COMPOUND, AND COMPOSITION FOR DETECTING GINGIPAIN, COMPOSITION FOR DIAGNOSING PORPHYROMONAS GINGIVALIS INFECTION, OR ANTIBACTERIAL COMPOSITION AGAINST PORPHYROMONAS GINGIVALIS USING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Inventeur(s)
Pae, Ae Nim
Kim, Yun Kyun
Lim, Sung Su
Abdildinova, Aizhan
Gotina, Lizaveta
Aziz, Hira
Choi, Yu Jeong
Kim, Hyun Jeong
Abrégé
The present invention relates to: a fluorescent compound represented by formula 1 or a pharmaceutically acceptable salt thereof; and a composition for detecting gingipain, a composition for diagnosing Porphyromonas gingivalis infection, or an antibacterial composition against Porphyromonas gingivalis using same.
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
A01N 43/713 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec au moins quatre atomes d'azote comme uniques hétéro-atomes du cycle
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
38.
SPENT SECONDARY BATTERY CATHODE REGENERATION SOLUTION AND CATHODE REGENERATION METHOD USING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Min Ah
Hong, Ji Hyun
Jung, Hun Gi
Choi, Jin Kwan
Chung, Kyung Yoon
Hwang, Ui Chan
Abrégé
Provided are a regeneration solution of a spent secondary battery cathode material, the regeneration solution including p-type redox molecules, a solvent, and a lithium salt, in which the p-type redox molecules have a reduction potential that is higher than or equal to 1.55 volt (V) and lower than or equal to 3.7 V with respect to a reduction potential (vs Li/Li+) of lithium, a method of regenerating a cathode material and a regenerated cathode material using this, and a method of recycling the regeneration solution.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Choi, Jee Hyun
Kim, Bowon
Kim, Jung Young
Abrégé
A device for monitoring a sleep state of a community mounted on each measurement target forming the community includes an electrode unit configured to measure biosignals including an electroencephalogram (EEG) and electromyography (EMG) of each measurement target forming the community, a control unit configured to compare the measured EEG and
A device for monitoring a sleep state of a community mounted on each measurement target forming the community includes an electrode unit configured to measure biosignals including an electroencephalogram (EEG) and electromyography (EMG) of each measurement target forming the community, a control unit configured to compare the measured EEG and
EMG with critical values and classify sleep and wake states of the measurement target, an indicating unit configured to emit light in different colors according to the sleep and wake states of the measurement target, and a recording and communication unit configured to store or transmit the measured EEG and EMG to an external device. Therefore, by measuring a sleeping behavior of each entity of the community and analyzing and visualizing the sleep and wake states in real time, it is possible to efficiently observe the interaction between sleep and an environment.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
DANA-FARBER CANCER INSTITUTE, INC. (USA)
Inventeur(s)
Ryu, Ju Hee
Kwon, Ick Chan
Ko, Youngji
Roberts, Thomas M
Zhao, Jean J
Ding, Liya
Abrégé
The present invention provides a BRCA-specific siRNA for the purpose of improving the sensitivity of cancer cells to a PARP inhibitor. The siRNA of the present invention can induce cancer cell death together with a PARP inhibitor in patients having a wild-type BRCA gene with low therapeutic efficacy of the PARP inhibitor. A fusion protein-siRNA complex for siRNA delivery, of the present invention, is introduced into cells via CD47, and thus can be delivered more specifically to cancer cells while being introduced with high efficiency, thereby maximizing a desired cell death effect.
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61K 31/502 - PyridazinesPyridazines hydrogénées condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. cinnoline, phtalazine
A61K 31/5025 - PyridazinesPyridazines hydrogénées condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
41.
ORGANIC WORKING SOLUTION FOR PHOTOCHEMICAL HYDROGEN PEROXIDE PRODUCTION AND METHOD FOR PRODUCING HYDROGEN PEROXIDE BY PHOTO-AUTOXIDATION UTILIZING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Byun, Jee Hye
Lee, Dong Ki
Abrégé
The present invention relates to an organic working solution for photochemical hydrogen peroxide production, and a method for producing hydrogen peroxide by photo-autoxidation utilizing the organic working solution.
The present invention relates to an organic working solution for photochemical hydrogen peroxide production, and a method for producing hydrogen peroxide by photo-autoxidation utilizing the organic working solution.
Specifically, the present invention relates to a method for producing hydrogen peroxide from an organic working solution in which oxidation of an aromatic alcohol and reduction of oxygen occur through photo-autoxidation of an aromatic carbonyl compound contained in the organic working solution, and the reduced oxygen.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Seon Joon
Hwang, Seung Sang
Lee, Albert
Oh, Taegon
Ko, Tae Yun
Hong, Junpyo
Abrégé
Disclosed in the present specification are a two-dimensional MXene surface-modified with a metal-organic network, a method of preparing the same, a MXene organic ink containing the same, and uses (e.g., an electromagnetic wave shielding material). In one aspect, the two-dimensional MXene surface-modified with a metal-organic network according to the present invention can use various organic ligands by linking the surface with the organic through the metal, and can be stably dispersed in various organic solvents, especially in industrial non-polar organic solvents as well as polar organic solvents, thereby being applied to a more general-purpose technologies, and securing stability against chemical oxidation to improve long-term stability.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Min Ah
Hong, Ji Hyun
Jung, Hun Gi
Choi, Jin Kwan
Chung, Kyung Yoon
Hwang, Ui Chan
Abrégé
The present invention relates to a regeneration solution of a waste secondary battery cathode material, a method for regenerating a cathode material and a regenerated cathode material, using same, and a method for recycling the regeneration solution, the regeneration solution comprising p-type redox molecules, a solvent, and a lithium salt, wherein the reduction potential of the p-type redox molecules is 1.55-3.7 V versus lithium (vs Li/Li+).
H01M 10/54 - Récupération des parties utiles des accumulateurs usagés
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
44.
CORE-SHELL TYPED COMPOSITE FILLER WITH HIGH THERMAL CONDUCTIVITY, POLYMER COMPOSITE MATERIAL COMPRISING THE SAME, AND METHOD FOR MANUFACTURING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Yang, Cheol-Min
Jang, Woo Ree
Kim, Namryeol
Lee, Seo Yun
Park, Sangki
Abrégé
The present invention relates to a core-shell typed composite filler including: a core including a thermosetting polymer resin; and a shell including a plurality of first nano/micro materials positioned on a surface of the core, and to a polymer composite material with the same applied. Further, the present invention also relates to a method of manufacturing a polymer composite material, the method includes: forming the core-shell typed composite filler; and dispersing the core-shell typed composite filler and the second nano/micro material into a polymer matrix.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (République de Corée)
Inventeur(s)
Nam, Min Ho
Lee, Hyo Won
Oh, Soo Jin
Lee, Seung Eun
Park, Hi Joon
Oh, Ju Young
Abrégé
The present invention relates to a composition for mimicking acupuncture treatment, comprising a Gq-DREADD expression vector administered to an acupoint as an active ingredient. The present invention provides a technique for mimicking acupuncture treatment by applying chemical genetics to an acupoint, thereby non-invasively enabling the expression of Gq-DREADD in neurons of an individual and the activation of the Gq-DREADD so as to enhance the cognitive and/or motor skills of the individual, and enabling the reduction of neuropathic pain and the alleviation of atopic dermatitis symptoms, and thus the present invention is expected to be used as a means for replacing acupuncture treatment in which the same result cannot be guaranteed depending on the operator.
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p. ex. clozapine, dilazèpe
A61K 31/5513 - 1,4-Benzodiazépines, p. ex. diazépam
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHMOLOGY (République de Corée)
Inventeur(s)
Choi, Myunghwan
Kim, Seonghoon
Chong, Kyuha
Yang, Sungwook
Abrégé
Disclosed are a patterned optical stimulation device and method. The patterned optical stimulation device according to one aspect includes: an imaging unit which generates a skin tissue image; a diagnosis unit which detects a region of interest from the skin tissue image and diagnoses the detected region of interest; and an optical stimulation unit which forms patterned treatment light corresponding to the region of interest and irradiates the region of interest with the formed patterned treatment light.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Yoon, Kyung Joong
Park, Mi Young
Park, Sun-Young
Yang, Sungeun
Kwon, Deok-Hwang
Ji, Ho Ll
Kim, Hyoungchul
Son, Ji-Won
Lee, Jong Ho
Kim, Byung Kook
Abrégé
The present invention includes: a porous structure containing an oxygen ion conductive material; and a coating layer disposed on the porous structure and containing an electronically conductive material, in which a content of the oxygen ion conductive material is greater than that of the electronically conductive material, and the coating layer is uniformly formed to a thickness of 20 nm or less.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kwon, Joon-Hyun
Kim, Hyun-Soo
Yang, Sang-Hyeok
Noh, Su-Jung
Lee, Han-Saem
Lee, Ji-Sung
Min, Byoung-Chul
Choi, Jong-Bum
Han, Dong-Soo
Abrégé
A spin Hall magnetic sensor includes a plurality of magnetic thin film units including a magnetic layer stacked on a non-magnetic layer, and a plurality of non-magnetic substances disposed between the plurality of magnetic thin film units, The magnetic includes a Wheatstone bridge structure to observe a magnetic Hall resistance generated by a spin orbit torque (SOT).
G01R 33/07 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs galvano-magnétiques des dispositifs à effet Hall
G01R 33/00 - Dispositions ou appareils pour la mesure des grandeurs magnétiques
G01R 33/09 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs galvano-magnétiques des dispositifs magnéto-résistifs
49.
BEARING STEEL WITH IMPROVED INSULATION PERFORMANCE
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Dong Hwi
Kwon, Soon Woo
Yoon, Sang Jae
Kang, Min Woo
Lee, Chung An
Hong, Seung Hyun
Kim, Hyun Ki
Kim, Dong Ik
Shim, Jae Hyeok
Jung, Woo Sang
Choi, Dong Jun
Abrégé
A bearing steel has improved insulation performance by forming a continuous insulating film. The bearing steel includes 0.65 to 1.0 mass % of carbon (C), 1.6 to 2.0 mass % of chromium (Cr), 1.5 to 3.0 mass % of aluminum (Al), 0.8 to 1.2 mass % of manganese (Mn), 0.7 to 1.0 mass % of silicon (Si), 0.1 to 0.3 mass % of nickel (Ni), 0.08 to 0.12 mass % of molybdenum (Mo), and a balance of iron (Fe), in which an oxynitride layer including a nitride layer and an oxide layer is formed on the surface of a material.
C22C 38/44 - Alliages ferreux, p. ex. aciers alliés contenant du chrome et du nickel et du molybdène ou du tungstène
C21D 8/02 - Modification des propriétés physiques par déformation en combinaison avec, ou suivie par, un traitement thermique pendant la fabrication de produits plats ou de bandes
C22C 38/00 - Alliages ferreux, p. ex. aciers alliés
C22C 38/02 - Alliages ferreux, p. ex. aciers alliés contenant du silicium
C22C 38/04 - Alliages ferreux, p. ex. aciers alliés contenant du manganèse
C22C 38/06 - Alliages ferreux, p. ex. aciers alliés contenant de l'aluminium
C23C 8/18 - Oxydation de la couche superficielle de matériaux ferreux
C23C 8/26 - Nitruration de la couche superficielle de matériaux ferreux
C23C 28/04 - Revêtements uniquement de matériaux inorganiques non métalliques
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Yong Bok
Ha, Yunseok
Kim, Jungwan
An, Byul
Abrégé
The present disclosure relates to a hybrid thrust bearing that combines an airfoil bearing and a magnetic bearing to support a rotating shaft with a disk-shaped thrust disk, and the magnetic bearing includes a disk-shaped housing into which the rotation shaft is inserted through a hole formed in a center and facing the thrust disk, a ring-shaped inner pole part formed around the hole on one side of the housing facing the thrust disk, a ring-shaped outer pole part disposed outside the inner pole part, an attachment part provided between the inner pole part and the outer pole part, and a coil stored in the attachment part, wherein a part of the airfoil bearing is inserted into the attachment part.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Byun, Jee Hye
Lee, Dong Ki
Moon, Byeong Cheul
Bolormaa, Bayarkhuu
Abrégé
The present invention relates to a method and process for preparing hydrogen peroxide, and more particularly, to a photochemical hydrogen peroxide preparation process performed by combining photoautoxidation and photocatalytic reactions in an organic reaction solution to which a catalytic amount of water is added using solar light as a main energy source.
C01B 15/026 - Préparation à partir de composés organiques à partir d'alcools
B01J 31/06 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des polymères
B01J 35/00 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Ihn, Yongseok
Na, Yunseong
Hwang, Donghyun
Yang, Sungwook
Abrégé
A robot arm is provided. The robot arm according to an aspect of the present disclosure comprises a motor portion; a support connected to the motor portion; first and second links connected to the motor portion and movable in a vertical direction; a first gimbal coupled to upper ends of the first and second links, respectively; third and fourth links coupled to the first gimbal; fifth and sixth links coupled to lower ends of the third and fourth links, respectively; seventh and eighth links coupled to central areas of the fifth and sixth links in the vertical direction; a second gimbal coupled to upper ends of the seventh and eighth links; ninth and tenth links coupled to the second gimbal; eleventh and twelfth links coupled to lower ends of the ninth and tenth links; and a top portion coupled to upper ends of the fifth and sixth links and upper ends of the eleventh and twelfth links.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lim, Sunghwan
Jeon, Sangseo
Han, Hyehyun
Abrégé
A method for a breast biopsy based on indirect magnetic resonance imaging (MRI) guidance of present disclosure, may comprises obtaining a breast MRI data of a patient, generating a deformable breast model using the breast MRI data, measuring real-time breast shape of the patient using a depth sensor, performing a real-time deformable registration using the deformable breast model and the real-time shape data, estimating movements of the MRI targets inside of the breast, performing a breast biopsy for the MRI targets.
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
G06T 3/40 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Donghun
Han, Sang Soo
Ow, Leslie Tiong Ching
Yoo, Hyukjun
Kim, Nayeon
Abrégé
There is provided a method and an apparatus for diagnosing an object placement error by using an artificial neural network by which feature data of the (N+1)-th stage among the feature data of a plurality of stages is generated by using any one feature data among a plurality of feature data generated in an operation process of a main network and feature data of the plurality of stages, and a placement error of at least one object is diagnosed by using an artificial neural network of a new structure, and thus, the diagnosis accuracy of a placement error of an object that is difficult to detect an edge, such as a transparent vial, may be greatly increased.
G06V 10/98 - Détection ou correction d’erreurs, p. ex. en effectuant une deuxième exploration du motif ou par intervention humaineÉvaluation de la qualité des motifs acquis
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
56.
SWAB SEALING MECHANISM, NASAL SPECIMEN EXTRACTION SYSTEM COMPRISING SAME, AND NASAL SPECIMEN EXTRACTION METHOD USING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Jongwon
Lee, Jong Bok
Abrégé
Provided is a swab sealing mechanism comprising: a cylinder holder which provides a receiving hole extending in a first direction; a cutting head on the cylinder holder; a cutting drive device which moves the cutting head in a second direction, which is a horizontal direction intersecting the first direction, on the cylinder holder; and a sealing drive device which rotates the cylinder holder about an axis parallel to the first direction, wherein the cutting head provides a cap placement hole.
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
57.
COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASE COMPRISING CENTAUREA CYANUS FLOWER EXTRACT
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Myung-Suk
Jung, Sang-Hoon
Tam, Thi Le
Nguyen, Bao Ngoc
Lee, Wook-Bin
Abrégé
The present invention relates to a composition for preventing, ameliorating or treating a muscle disease, comprising a Centaurea cyanus flower extract. The Centaurea cyanus flower extract of the present invention has the effects of enhancing grip strength, increasing muscle weight, and improving exercise performance and the like. In addition, a composition comprising the Centaurea cyanus flower extract as an active ingredient, according to the present invention, is a natural medicine and can be applied to various products such as pharmaceutical compositions, food compositions and quasi-drug compositions for the prevention, treatment, amelioration or the like of muscle diseases.
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Lee, Dong Ki
Moon, Byeong Cheul
Koh, Jai Hyun
Lee, Woong Hee
Won, Dahye
Lee, Ung
Oh, Hyung-Suk
Min, Byoung Koun
Abrégé
Exemplary embodiments of the present invention may provide a continuous production system for 2,5-furandicarboxylic acid (FDCA), the continuous production system including: raw material supply units supplying an aqueous 5-hydroxymethylfurfural (HMF) solution and a basic aqueous solution, respectively; a micro-mixing unit mixing the aqueous HMF solution and the basic aqueous solution supplied from the raw material supply units, respectively, to form a raw material mixture; an electrochemical reaction unit synthesizing FDCA while passing the raw material mixture introduced from the micro-mixing unit in a single pass; and a product storage unit storing a product discharged from the electrochemical reaction unit.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Park, Young Tae
Park, Jisu
Min, Huitae
Kim, Taehyun
Kim, Jin-Woo
Kim, Tae Jung
Kim, Jin Chul
Ham, Jung Yeob
Abrégé
The present invention relates to a use of a fermentation product of Lacticaseibacillus casei of cannabis stems and an extract thereof for ameliorating skin wrinkles caused by photoaging, and to an anti-wrinkle cosmetic composition or pharmaceutical composition including the fermentation product.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Dong Ki
Moon, Byeong Cheul
Koh, Jai Hyun
Lee, Woong Hee
Won, Dahye
Lee, Ung
Oh, Hyung-Suk
Min, Byoung Koun
Abrégé
Embodiments of the present invention may provide a 2,5-furandicarboxylic acid continuous production system comprising: raw material supply units which respectively supply an aqueous 5-hydroxymethylfurfural (HMF) solution and an aqueous base solution; a micro-mixing unit which mixes the aqueous 5-HMF solution and the aqueous base solution that are respectively supplied from the raw material supply units, to form a raw material mixture; an electrochemical reaction unit which synthesizes 2,5-furandicarboxylic acid while passing the raw material mixture flowing in from the mixing unit, through a one-pass; and a product storage unit which stores a product discharged from the electrochemical reaction unit.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Hong, Yeon-Sun
Yang, Yoo Soo
Kim, In-San
Abrégé
The present invention relates to a recombinant exosome containing hyaluronidase and a use thereof, and more particularly to a recombinant exosome that presents hyaluronidase on its surface and use thereof as an anticancer agent.
A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à quatre chaînons, p. ex. taxol
A61K 31/407 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil condensés avec des systèmes hétérocycliques, p. ex. kétorolac, physostigmine
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61K 38/47 - Hydrolases (3) agissant sur des composés glycosyliques (3.2), p. ex. cellulases, lactases
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Yang, Yoosoo
Jang, Ho-Chung
Park, Daeho
Kim, Myung-Gyu
Abrégé
Disclosed in the present application is a composition for alleviating renal functional impairment, comprising, as an active ingredient, milk-derived exosomes in which nucleic acid oligomers are encapsulated. The composition comprises milk-derived exosomes in which PTP1B siRNA is encapsulated. The composition provides the effects of reducing blood urea nitrogen and/or creatinine values having increased because of renal damage and/or reducing inflammatory responses in renal cells.
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Im, Heh-In
Bae, Jin Hee
Frankiv, Nazarii
Abrégé
According to the present disclosure, the relation between the MeCP2 expression level and depression in D2R neurons of the ventral striatum was first found, and it was confirmed that MeCP2 in D2R neurons of the ventral striatum was significantly decreased due to depressive symptoms, and depressive symptoms were improved when MeCP2 expression in the neurons was up-regulated. Accordingly, the expression level of MeCP2 in D2R neurons of the ventral striatum is provided as a biomarker for diagnosing depression and the up-regulation of the MeCP2 expression is provided as a treatment strategy for depression, and thus, it is expected to be useful as a development platform for drugs for preventing or treating depression in the future.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
64.
TWO-DIMENSIONAL METAL CARBIDE, NITRIDE, AND CARBONITRIDE FILMS AND COMPOSITES FOR EMI SHIELDING
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Gogotsi, Yury
Anasori, Babak
Alhabeb, Mohamed H.
Hatter, Christine B.
Koo, Chong Min
Hong, Soon Man
Shahzad, Faisal
Abrégé
The present disclosure is directed to materials which provide electromagnetic shielding and methods of providing such electromagnetic shielding. In particular, the present disclosure describes the use of two-dimensional transition metal carbide, nitride, and carbonitride materials for this purpose.
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Lee, Sun Mi
Kim, Jiwon
Son, Hyeoncheol
Ko, Ja Kyong
Gong, Gyeongtaek
Ahn, Jung Ho
Um, Youngsoon
Abrégé
The present disclosure discloses a strain having resistance by neutralizing furfural, an inhibitor derived from lignocellulosic biomass, based on a technique using aldehyde dehydrogenase and a method of using the same. According to the present disclosure, furfural, an inhibitor derived from lignocellulosic biomass, is neutralized based on a technique using aldehyde dehydrogenase, so that a resistant strain overexpresses aldehyde dehydrogenase (EcAldH) in Yarrowia lipolytica, which has the ability to produce yeast oil, and has resistance to furfural, a biomass-derived inhibitor. Accordingly, even in the medium containing furfural, it can provide excellent strain growth and yeast oil production ability.
Korea Institute of Science and Technology (République de Corée)
Inventeur(s)
Shin, Ho Cheol
Min, Hong Seok
Lee, Sang Heon
Lee, Sang Soo
Chae, Mun Seok
Jung, Wo Dum
Song, In Woo
Kim, So Young
Cho, Young Whan
Abrégé
Disclosed are a sulfide-based solid electrolyte including boron and having a face-centered cubic crystalline phase and a method of manufacturing the same.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Son, Moon
Abrégé
Disclosed embodiments are directed to providing an apparatus and method for summarizing information using a generative artificial intelligence model that is capable of generating an answer sentence and an image summarizing and organizing numerous information associated with a user's search term using a pre-trained generative artificial intelligence model, and generating and providing answer content that includes the generated sentence and image.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Jeongryul
Kim, Keri
Cho, Hong Jun
Kim, Sang Kyung
Abrégé
A gripper for gripping a target has a first support section, a second support section spaced apart from the first support section in a direction of a rotation center axis, and a plurality of elastic wires supported across the first support section and the second support section. A first grip area surrounded by the plurality of elastic wires is formed between the first support section and the second support section upon a relative rotation of the first support section and the second support section around the rotation center axis, and the first grip area becomes narrower until all the plurality of elastic wires come into contact with the target by the relative rotation of the first support section and the second support section, and the plurality of elastic wires is tightened to grip the target entering the first grip area.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Nam, Suk Woo
Lee, Yu-Jin
Kim, Yong Min
Jeong, Hyangsoo
Sohn, Hyuntae
Abrégé
Disclosed are a catalyst with improved durability, a method for producing same, and a method for dehydrogenating ammonia using same. The catalyst comprises: a support; a transition metal supported on the support; and hexagonal boron nitride synthesized on the transition metal. The hexagonal boron nitride may be synthesized from ammonia borane. The present disclosure has the effect of providing a hexagonal boron nitride-based catalyst with high compatibility by applying an ammonia borane solution onto a transition metal supported on a support, followed by heat treatment under an ammonia atmosphere.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Um, Youngsoon
Lee, Sun Mi
Gong, Gyeongtaek
Ko, Ja Kyong
Ahn, Jung Ho
Moon, Taekwan
Abrégé
ClostridiumClostridium sp. strain having improved carbon dioxide fixation ability, a method for producing biochemicals from carbon dioxide using the novel strain, and a method for fixing carbon dioxide using the novel strain. The novel strain, according to the present disclosure, has a significantly improved carbon dioxide utilization ability compared to conventional acetogen strains, and thus, it is possible to efficiently produce biochemicals derived from carbon dioxide through fermentation of the new strain.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Chang, Hye Jung
Kim, Dae-Young
Choi, Ha Neul
Abrégé
The present invention relates to a holder device for SEM-EDS analysis, for securing a sample, the holder device being for a SEM-EDX analysis device. More specifically, the present invention relates to a holder device for SEM-EDS analysis, which minimizes damage to a sample and is reusable. The purpose of the present invention is to provide a holder device for SEM-EDS analysis, which, in a SEM-EDX analysis device having an energy dispersive X-ray spectroscope (EDS) detector attached to a scanning electron microscope (SEM), minimizes damage to a sample and is reusable. In addition, the purpose of the present invention is to provide a holder device for SEM-EDS analysis, which is easily detachable and comprises a chemical component in which a holder component is not detected when detecting using an EDS detector.
G01N 23/2204 - Supports d’échantillons à cet effetMoyens de transport des échantillons à cet effet
G01N 23/2251 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en utilisant des microsondes électroniques ou ioniques en utilisant des faisceaux d’électrons incidents, p. ex. la microscopie électronique à balayage [SEM]
72.
MAGNESIUM ELECTRODE, METHOD FOR PREPARING SAME, AND MAGNESIUM SECONDARY BATTERY INCLUDING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Oh, Si Hyoung
Hwang, Jinyeon
Lee, Minah
No, Woo Joo
Chung, Kyung Yoon
Abrégé
Embodiments of the present invention can provide a magnesium electrode comprising: an electrode plate including magnesium; and a protection layer positioned on at least one portion of the surface of the electrode plate, wherein the protection layer includes a phosphate ester compound.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Ham, Jungyeob
Kim, Jeong Kook
Song, Jung Ho
Kim, Young-Joo
Kim, Taejung
Jeon, Yong Sic
Kim, Jiyul
Abrégé
The present invention relates to a pharmaceutical composition for prevention or treatment of inflammatory disease, comprising cannabiorcol or a derivative thereof. The cannabiorcol or a derivative thereof of the present invention inhibits the expression of IL-1β-induced MMP and the activity of NF-κB and MAPK, and inhibits the expression of inflammation-related factors and thus may exhibit a prevention, reduction, or treatment effect on inflammatory disease.
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
74.
MAGNESIUM ELECTRODE, METHOD FOR PREPARING THE SAME, MAGNESIUM SECONDARY BATTERY INCLUDING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Oh, Si Hyoung
Hwang, Jinyeon
Lee, Minah
No, Woo Joo
Chung, Kyung Yoon
Abrégé
Exemplary embodiments of the present invention may provide a magnesium electrode including an electrode plate including magnesium and a protective layer located on at least a part of a surface of the electrode plate, in which the protective layer includes a phosphoric acid alkyl ester compound.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Hwang, Donghyun
Song, Changseob
Abrégé
The present disclosure relates to a magnetic field-based jamming mechanism with variable stiffness and shape adaptation functionalities that can adapt to various characteristics (shape, softness, etc.) of the external environment, and can easily grip objects having various shapes since it grips objects using changes in the stiffness of soft magnetic particles.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Chang, Hye Jung
Kim, Dae-Young
Choi, Ha Neul
Abrégé
The present disclosure relates to an SEM-EDS analysis holder device configured to fix a sample in an SEM-EDX analysis apparatus. More specifically, the present disclosure relates to an SEM-EDS analysis holder device capable of minimizing damage to a sample and reusing the sample. An object of the present disclosure is to provide an SEM-EDS analysis holder device capable of minimizing damage to a sample and reusing the sample in an SEM-EDX analysis apparatus configured by attaching an energy dispersive X-rays spectroscope (EDS) detector to scanning electron microscopy (SEM). Another object of the present disclosure is to provide an SEM-EDS analysis holder device that is easily attached or detached and includes chemical components detected by an EDS detector without a component of a holder.
G01N 23/20025 - Porte-échantillons ou leurs supports
G01N 23/223 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en irradiant l'échantillon avec des rayons X ou des rayons gamma et en mesurant la fluorescence X
G01N 23/2251 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en utilisant des microsondes électroniques ou ioniques en utilisant des faisceaux d’électrons incidents, p. ex. la microscopie électronique à balayage [SEM]
77.
SINGLE ATOM CATALYST BASED ON CARBON NANOTUBE AND MANUFACTURING METHOD THEREOF
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Nam Dong
Jung, Jae Young
Yoo, Sung Jong
Ku, Bon-Cheol
Kim, Min Woo
Jeong, Hyeonsu
Abrégé
Provided is a single atom catalyst based on a carbon nanotube according to the present invention including a carbon support; and single atom metals supported on the carbon support, wherein the carbon support has a cone shape with an empty space formed therein and includes at least one carbon support having an open tip of the corn-shaped carbon support.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Ihn, Yongseok
Lee, Junwon
Yang, Sungwook
Hwang, Donghyun
Abrégé
A forceps unit and a forceps apparatus are provided. The forceps unit according to an aspect of the present disclosure may comprise a base portion connected to a motor; a grasping portion disposed in front of the base portion and grasping a surgical instrument; a connecting portion connecting the base portion and the grasping portion; and a plurality of optical fibers, wherein some of the plurality of optical fibers are fixed to the grasping portion and others of the plurality of optical fibers are fixed to the base portion, wherein the plurality of optical fibers may include a first optical fiber disposed in a central region of the grasping portion and second to fifth optical fibers radially disposed with respect to the first optical fiber, and the first optical fiber may protrude further forward than the second to fifth optical fibers.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Nho, Chu Won
Kim, Myungsuk
Nam, Yunseong
Abrégé
The present invention relates to a composition for preventing or treating liver fibrosis, which includes a Sanguisorba officinalis extract as an active ingredient, and more particularly, to a composition for preventing or treating liver fibrosis, which includes a Sanguisorba officinalis extract or ziyuglycoside. The Sanguisorba officinalis extract or ziyuglycoside of the present invention inhibits liver fibrosis and the expression of a liver fibrosis-related gene, so it may be effectively used in the composition for preventing or treating liver fibrosis.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
80.
ANION EXCHANGE MEMBRANE AND METHOD FOR MANUFACTURING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Albert Sung Soo
Hwang, Seung Sang
Kim, Seon Joon
Oh, Taegon
Jung, Ji Yoon
Park, Young Sang
Ku, Jinsuk
Kim, Junggyu
Abrégé
The present specification pertains to an anion exchange membrane and a method for manufacturing same. An electrochemical catalyst according to an embodiment of the present invention has the effect of exhibiting high ion exchange ability and excellent mechanical strength.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Taeuk
Lim, Sang Min
Cha, Eunji
Kang, Jeong Wook
Kim, Yunjae
Choi, In Young
Abrégé
The present invention provides a composition including a novel pyridoindole derivative compound as an active ingredient for the prevention or treatment of neurodegenerative diseases. Departing from conventional symptomatic treatments that focus on controlling peripheral symptoms of neurodegenerative diseases, particularly various tauopathies caused by Tau protein aggregation, the present invention achieves the fundamental removal of the cause of neurodegeneration by significantly inhibiting the interaction between Tau protein and synaptogyrin-3.
A61K 31/444 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. amrinone
A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
82.
POLYMER SEPARATOR AND METHOD FOR MANUFACTURING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Shim, Ji Min
Kwon, Da Sol
Lee, Min Ah
Kim, Hyung Seok
Gong, Sang Hyuk
Kim, Sang Ok
Abrégé
2244OH, and at least one selected from the group consisting of ethanol, methanol, and glycerol (S2); and subjecting the porous separator to a thiol-ene click reaction with a compound having a thiol group (-SH) (S3).
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Jung-Hoon
Lee, Weon Gyu
Abrégé
An electronic device for obtaining common supercell information according to an embodiment of the inventive concept stores first and second lattice matrices, indicative of surface structures of two different materials in a real plane, and a conversion table. The processor retrieves these matrices, obtains complex lattice matrices for both surfaces in a complex plane, and determines a lattice constant ratio from them. Using this ratio, the processor refers to the conversion table to obtain phase information and a conversion matrix. Finally, it calculates common supercell information for both materials based on the lattice constant ratio, phase information, and conversion matrix, and outputs it via the user interface device.
CYCLIC OLIGOMER, METHOD FOR PRODUCING SAME, COMPOUNDING MATERIAL AND COMPOSITE MATERIAL COMPRISING SAME, AND MEDICAL ARTICLE SURFACE-MODIFIED OR SURFACE-TREATED THEREWITH
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Joung, Yoon Ki
Kang, Seung Min
Lee, Ju Ro
Yang, Seung Won
Kwak, Seung Chul
Abrégé
The present invention relates to a cyclic oligomer, a method for producing same, a compounding material and a composite material which comprise same, and a medical article surface-modified or surface-treated therewith. The cyclic oligomer can be prepared through ring-expansion cationic polymerization using a cyclic hemiacetal ester-based initiator and a vinyl ether monomer, and has surface segregating properties.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Seo, Minah
Lee, Geon
Roh, Yeeun
Abrégé
Provided is a security code including a substrate, metamaterials on the substrate, a signal modulation pattern on the metamaterials, and a capping layer covering the signal modulation pattern and the metamaterials, wherein the metamaterials include a pair of metal patterns facing each other, the signal modulation pattern covers a portion of the metal patterns, and expose remaining of the metal patterns, and the signal modulation pattern has a different material from each of the metal patterns.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Jinseok
Jang, Minsu
Lee, Deukhee
Han, Hyehyun
Kim, Byung Kook
Lee, Byung Chul
Abrégé
Disclosed embodiments aim to provide an apparatus and method for three-dimensional navigation of a medical tool that enables identifying the three-dimensional shape and position of the medical tool within a human body. To achieve the above object, the disclosed embodiment includes a three-dimensional high-resolution image acquisition unit configured to acquire a three-dimensional high-resolution image of a human organ that is targeted for a medical procedure; a three-dimensional shape data acquisition unit configured to acquire three-dimensional shape data of a medical tool of a flexible material in real time; a registration unit configured to register the three-dimensional high-resolution image and the three-dimensional shape data with a reference point; and a display unit configured to display an image registered by the registration unit.
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
G06T 7/50 - Récupération de la profondeur ou de la forme
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Jung, Hun-Gi
Chung, Kyung Yoon
Yu, Seungho
Lee, Minah
Shim, Jimin
Park, Jungjin
Shin, Hyeon-Ji
Kim, Jun Tae
Kim, A-Yeon
Oh, Hyeon Seong
Lee, Minyoung
Lim, Hee-Dae
Abrégé
Provided is a method of producing a composite solid electrolyte. The method includes step S10 of producing an oxide-based solid electrolyte membrane by electrospinning a mixture including an oxide-based solid electrolyte precursor and a polymer, step S20 of producing an oxide-based solid electrolyte support by removing the polymer inside the oxide-based solid electrolyte membrane, and step S30 of causing the oxide-based solid electrolyte support to be impregnated with a sulfide-based solid electrolyte using a sulfide-based solid electrolyte precursor solution including a sulfide-based solid electrolyte precursor and a solvent.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Myung Suk
Jung, Sang Hoon
Ko, Hye Jin
Le, Tam Thi
Nguyen, Ngoc Bao
Lee, Wook Bin
Abrégé
The present invention relates to a composition for the prevention or treatment of a muscle disease, comprising an extract of Ponciri Fructus. The extract of the present invention has the effect of increasing the expression of genes related to myotube cell differentiation and/or athletic performance, increasing muscle weight, and/or improving athletic performance.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Myung-Suk
Jung, Sang-Hoon
Ko, Hye-Jin
Lee, Wook-Bin
Nguyen, Bao-Ngoc
Tam, Thi-Le
Abrégé
The present invention relates to a composition containing a Ponciri fructus extract for preventing or treating muscle diseases. The Ponciris fructus extract of the present invention increases the expression of genes related to myoblast differentiation and exercise performance, increases muscle mass, and improves exercise performance.
Korea Institute of Science and Technology (KIST) (République de Corée)
Inventeur(s)
Gray, Nathanael S.
Fischer, Eric S.
Ferguson, Fleur M.
Donovan, Katherine
Bushman, Jonathan W.
Sim, Taebo
Bhunia, Debabrata
Ryu, Seongshick
Abrégé
The present invention relates to bifunctional compounds for targeted kinase degradation, methods for treating diseases or conditions mediated by aberrant kinase activity, and methods for identifying degradable kinases and optimal kinase:scaffold pairs.
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/4725 - Isoquinoléines non condensées, p. ex. papavérine contenant d'autres hétérocycles
A61K 31/5025 - PyridazinesPyridazines hydrogénées condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
91.
MODE-LOCKED RESONATOR AND ULTRASHORT PULSE LASER COMPRISING THE SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Song, Yong-Won
Moon, Hyowon
Kovalchuk, Oleksiy
Lee, Sungjae
Abrégé
Disclosed are a mode-locked resonator according to an embodiment and an ultrashort pulse laser comprising the mode-locked resonator. The mode-locked resonator according to an embodiment includes a resonator including a shape of a sphere; and a saturable absorber coated on a surface of the resonator, wherein the resonator is coupled with some photons traveling in a tapered optical fiber disposed near the mode-locked resonator and interacts with the saturable absorber based on a Whispering Gallery Mode (WGM).
H01S 3/1118 - Absorbeurs saturables à semi-conducteurs, p. ex. miroirs absorbeurs saturables à semi-conducteurs [SESAM]Absorbeurs saturables à l'état solide, p. ex. à base de nanotubes de carbone [CNT]
Korea University Research and Business Foundation (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Seoul National University R&DB Foundation (République de Corée)
Inventeur(s)
Kim, Young Keun
Jeon, Yoo Sang
Jeong, Eunjin
Yoo, Sung Jong
Nam, Ki Tae
Im, Sang Won
Abrégé
Disclosed herein is a technique for synthesizing chiral magnetic nanocoils using an electrodeposition technique, which can be used to fabricate magnetic nanosensors capable of generating an electric field by strongly reacting to an external magnetic field, such as Faraday's law of electromagnetic induction at the nanoscale, depending on the coil shape of the nanostructure. In accordance with one embodiment, a method of synthesizing a chiral magnetic nanocoil may include generating a primary particle composed of metal ions by applying an external electric field, binding a chiral molecule to a surface of the generated primary particle, and controlling an assembly direction of a next primary particle by the bound chiral molecule.
AGENCY FOR DEFENSE DEVELOPMENT (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Laehyun
Han, Yaeeun
Ha, Jihyeon
Abrégé
A method for recognizing blink and eye movement based on electroencephalogram (EEG) and a system thereof are disclosed. The method includes measuring a subject's EEG-based electrooculogram (EOG) signal (hereinafter referred to as “EOG signal”) using three electrodes connected to an EEG head cap. The method further includes performing potential blink detection and zero crossing detection using the EOG signal, and generating a plurality of parameters used for blink and eye movement classification using the EOG signal depending on presence or absence of the potential blink and the zero crossing. In addition, the method further includes classifying the blink and up/down/left/right eye movements of using the plurality of parameters.
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Bang, Eun-Kyoung
Keum, Gyo Chang
Nam, Jae- Hwan
Bae, Seohyeon
Faisal, Muhammad
Kwon, Sung Pil
Yoo, Soyeon
Abrégé
The present disclosure relates to a novel lipid compound and a lipid nanoparticle composition including the same and, more specifically, the lipid nanoparticle composition includes ionized lipid, helper lipid, PEG-lipid, and additives, and may mitigate changes and side effects in the delivery mechanism and enhance the protein expression efficiency by including a biofriendly vitamin-based novel lipid compound and helper lipids including neutral lipids.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
C07C 235/08 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone acyclique d'un radical hydrocarboné substitué par des atomes d'oxygène liés par des liaisons simples
C07C 235/10 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné le squelette carboné étant acyclique et saturé ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone acyclique d'un radical hydrocarboné substitué par des atomes d'azote ne faisant pas partie de groupes nitro ou nitroso
C07D 207/04 - Composés hétérocycliques contenant des cycles à cinq chaînons, non condensés avec d'autres cycles, ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle avec uniquement des atomes d'hydrogène ou de carbone liés directement à l'atome d'azote du cycle ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
C07D 211/06 - Composés hétérocycliques contenant des cycles pyridiques hydrogénés, non condensés avec d'autres cycles avec uniquement des atomes d'hydrogène et de carbone liés directement à l'atome d'azote du cycle ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
C07D 231/12 - Composés hétérocycliques contenant des cycles diazole-1, 2 ou diazole-1, 2 hydrogéné non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle
C07D 265/30 - Oxazines-1, 4Oxazines-1, 4 hydrogénées non condensées avec d'autres cycles
C07D 295/15 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de carbone du cycle avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile avec les atomes d'azote du cycle et les atomes de carbone comportant trois liaisons à des hétéro-atomes liés à la même chaîne carbonée, qui n'est pas interrompue par des carbocycles à une chaîne acyclique saturée
C07D 339/04 - Cycles à cinq chaînons comportant les hétéro-atomes en positions 1, 2, p. ex. acide lipoïque
C07D 413/10 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant des cycles aromatiques
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
95.
PHARMACEUTICAL COMPOSITION FOR ENHANCING IMMUNITY OR ANTI-CANCER ACTIVITY INCLUDING EXTRACT OF PSEUDOLYSIMACHION NAKAIANUM (OHWI) T.YAMAZ AS ACTIVE INGREDIENT
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kwon, Jaeyoung
Kwon, Hak Cheol
Kim, Won Kyu
Lee, Choong-Gu
Park, Inwha
Lee, Hyeon-Seong
Song, Sungmin
Hwang, Hoseong
Lee, Soon Kwang
Baek, Jong Gwon
Kim, Dong Hoon
Kwon, Yujin
Cho, Su-Yeon
Jang, Dae Sik
Abrégé
The present disclosure is completed by confirming the differentiation into Th17 and its activity-increasing function and the differentiation into Treg and its activity-suppressing function in compounds isolated from Pseudolysimachion nakaianum (Ohwi) T. Yamaz. The composition of the present disclosure increases the immune response by simultaneously regulating Th17 and Treg cell groups and their activities, and thus may be applied for the prevention and treatment of cancer and infectious diseases. According to the present disclosure, there is an advantage of having very few or no side effects by using Pseudolysimachion nakaianum (Ohwi) T. Yamaz, a natural product with safety that has been verified for a long time. Therefore, the present disclosure is expected to be used in various fields such as drugs, quasi-drugs, cosmetic materials, functional biomaterials, and functional food materials for immunity reinforcement and improvement, prevention, or treatment of infectious diseases and tumors.
A61K 31/7034 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
96.
Composition for the prevention, improvement or treatment of allergic diseases comprising an extract of Cassia mimosoides L. as an active ingredient
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Myung Suk
Jung, Sang Hoon
Lee, Wook Bin
Le, Tam Thi
Kang, Tae Kyeom
Abrégé
The present invention relates to a composition for the prevention, improvement or treatment of allergic diseases containing a Cassia mimosoides L. extract as an active ingredient, and more specifically, to a composition for the prevention, improvement or treatment of allergic diseases containing an ethanol extract of Cassia mimosoides L. as an active ingredient. In the present invention, the effect of Cassia mimosoides L. extract in treating allergic respiratory diseases was confirmed in an animal model of allergic asthma, and the anti-allergic effect of the compounds isolated from an ethanol extract of Cassia mimosoides L. was confirmed. Therefore, Cassia mimosoides L. extract of the present invention can be useful as a composition for preventing, improving, or treating allergic respiratory diseases, particularly allergic asthma or allergic bronchitis.
A61K 31/085 - Éthers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/216 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides ayant des cycles aromatiques, p. ex. bénactizyne, clofibrate
A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (République de Corée)
Inventeur(s)
Kim, Se Hoon
Yang, Jin Kyoung
Seitkazina, Assel
Souza, Ana Paula Mesquita
Cho, Yu Ri
Jeong, Han-Sin
Abrégé
The present invention relates to nanoparticles, a pharmaceutical composition comprising same for preventing or treating cancer or a cell hyperplasia disorder, and the like, the nanoparticles comprising: a methylene blue-organic acid complex; a cationic adjuvant-organic acid complex; and an amphiphilic polymer, wherein the nanoparticles are an agent having excellent drug properties and permeability, and are composed only of substances in clinical use so as to have low barriers to clinical entry and high potential for commercialization. In addition, the nanoparticles make it possible to have photodynamic therapy and immunotherapy, simultaneously, and thus may be utilized in the field of preventing, ameliorating, or treating cancer or a cell hyperplasia disorder.
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Kim, Suhyun
Kim, Yu-Jin
Park, Dogyun
Abrégé
An apparatus and method for generating training data according to an embodiment is disclosed. The apparatus for generating training data according to an embodiment includes at least one processor and a memory to store instructions for executing the at least one processor, wherein upon being executed by the at least one processor, the instructions allow the at least one processor to output a first image for one sample vector from a first generator included in the apparatus, and generate a second image from a second generator included in the apparatus based on the first image and a feature map extracted from a convolution block for each stage of a lightweight target model for the first image.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
99.
SURFACE-MODIFIED PLANT-DERIVED EXTRACELLULAR VESICLES AND TARGETED DRUG DELIVERY SYSTEM USING SAME
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Moon, Kyunghwan
Kang, Ji Yoon
Abrégé
The present invention relates to: plant-derived extracellular vesicles that are surface-modified with a phospholipid including functional groups and a targeting substance; a preparation method therefor; and a drug delivery system or pharmaceutical composition using same. The extracellular vesicles are stabilized and can be mass-produced, and thus are applicable for use in intracellular mass transfer.
A61K 47/24 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p. ex. cyclométhicone ou phospholipides
100.
SAMPLE COLLECTION METHOD AND APPARATUS USING IMAGE-BASED CONTROL
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Yang, Sungwook
Hwang, Gyubin
Lee, Jongwon
Abrégé
The present specification relates to a technique for controlling a robot using an image. A method by which a sample collection apparatus collects a sample comprises: acquiring an image including a target; detecting a sample collection area and a sample collection means from the acquired image; using a drive means connected to the sample collection means to cause the sample collection means to approach the detected sample collection area; and compensating in real time for an error in the image between the tip of the sample collection means and the sample collection area, which changes depending on the approach.
A61B 10/02 - Instruments pour prélever des échantillons cellulaires ou pour la biopsie
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre