Abrégé

Provided is a viral vector delivery system for the porcine respiratory tract and digestive tract. The viral vector delivery system comprises a backbone plasmid obtained by inserting full-length cDNA of porcine enterovirus type B into a pUC57 plasmid, and a helper plasmid obtained by inserting a green fluorescent protein-encoding gene into plasmid pCAG-T7-polymerase. The virus titer of the viral vector delivery system can reach 107.755050 per mL, and porcine respiratory tract and digestive tract pathogenic epitopes are inserted into the backbone plasmid, which has a good immune effect and can be used for constructing candidate strains of porcine respiratory tract and digestive tract vaccines.

Classes IPC  ?

• C12N 15/8 -
• C12N 15/64 - Méthodes générales pour la préparation du vecteur, pour son introduction dans la cellule ou pour la sélection de l'hôte contenant le vecteur
• C12N 15/65 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression utilisant des marqueurs
• A61K 39/12 - Antigènes viraux
• A61K 39/02 - Antigènes bactériens
• A61P 31/20 - Antiviraux pour le traitement des virus ADN
• A61P 31/04 - Agents antibactériens

Abrégé

Embodiments disclosed herein relate to an autonomous work excavator and an operation method therefor. According to an embodiment, an autonomous work excavator comprises: a front work device including an arm, a boom, and a bucket; a sensor device configured to collect state information about the excavator and information relating to the surrounding environment; and a processor electrically connected to the front work device and the sensor device. The processor can control so as to: conduct an excavation operation on the basis of work instructions so that earth and sand are loaded in the bucket; calculate the zero moment point (ZMP) of the force acting on the excavator on the basis of mass information about at least a portion of the front work device after the excavation operation; and acquire a work trajectory for processing the earth and sand loaded in the bucket by using the information relating to the ZMP and the surrounding environment.

Classes IPC  ?

• E02F 9/20 - EntraînementsDispositifs de commande
• E02F 9/24 - Dispositifs de sécurité

Abrégé

The present invention relates to a plasma actuator for flow control and, more specifically, to a plasma actuator for flow control, the actuator generating plasma so as to control surrounding flow. The plasma actuator for flow control, of the present invention, can actively and effectively control the generation of plasma according to changes in the surrounding flow environment while using relatively little electric power.

Classes IPC  ?

• H05H 1/24 - Production du plasma

Abrégé

Provided is a credit-based multipath data transmission method for load balancing of a data center network, the method comprising the steps of: transmitting a credit request packet to a receiver device; in response to the credit request packet, determining at least one first path along which credit packets can be received earliest from the receiver device, among all the communicable paths to the receiver device; each time that a credit packet is received through the first path from the receiver device, transmitting a data packet to the receiver device through the first path in response to the credit packet, wherein the credit packets received through the first path are in one-to-one correspondence with the data packets transmitted to the receiver device through the first path; and when there are no more data packets left to transmit to the receiver device, transmitting a credit stop packet to the receiver device.

Classes IPC  ?

• H04L 12/707 - Prévention ou récupération du défaut de routage, p.ex. reroutage, redondance de route "virtual router redundancy protocol" [VRRP] ou "hot standby router protocol" [HSRP] par redondance des chemins d’accès
• H04L 12/753 - Découverte de l’arborescence de routage, p.ex. conversion de la topologie maillée de réseau en topologie arborescente
• H04L 12/803 - Commande de flux ou commande de congestion Équilibrage de charge, p.ex. répartition du trafic entre multiples liens
• H04L 12/841 - Actions liées à la commande de flux utilisant des données temporelles, p.ex. temps d'aller retour [RTT]
• H04L 12/801 - Commande de flux ou commande de congestion

Abrégé

The present invention relates to a centrifugal pump impeller having a serration structure applied thereto, and more specifically, to a centrifugal pump impeller having a serration structure applied thereto, the impeller having a structure enabling the reduction of a vortex generated at the end of an impeller blade, thereby enabling the efficiency of a centrifugal pump to be increased. The centrifugal pump impeller having a serration structure applied thereto, according to the present invention, has a serration structure applied to an impeller blade of a centrifugal pump, and thus has an effect whereby a vortex generated at the impeller blade is reduced, and thus noise and vibration of the centrifugal pump are suppressed, and the efficiency of the centrifugal pump is increased.

Classes IPC  ?

• F04D 29/24 - Aubes
• F04D 29/22 - Rotors spécialement pour les pompes centrifuges
• F04D 29/66 - Lutte contre la cavitation, les tourbillons, le bruit, les vibrations ou phénomènes analoguesÉquilibrage

Abrégé

The present invention relates to a cross-flow fan and housing, and more specifically, to a cross-flow fan and housing having a structure enabling the reduction of a flow separation phenomenon occurring at the cross-flow fan and housing, thereby enabling increased energy efficiency. The cross-flow fan and housing, according to the present invention, has an effect whereby a flow separation phenomenon occurring at the cross-flow fan and housing is reduced, and thus noise and vibration of a fluid machine are suppressed, and the efficiency of the fluid machine is increased.

Classes IPC  ?

• F04D 29/42 - Carters d'enveloppeTubulures pour le fluide énergétique pour pompes radiales ou hélicocentrifuges
• F04D 29/46 - Moyens de guidage du fluide, p. ex. diffuseurs réglables
• F04D 29/30 - Aubes
• F04D 29/28 - Rotors spécialement adaptés aux fluides compressibles pour pompes centrifuges ou hélicocentrifuges

Abrégé

The present invention relates to a method for preparing fuel cell catalyst iron phosphide nanoparticles, and fuel cell catalyst iron phosphide nanoparticles prepared thereby. More specifically, provided is a method for preparing fuel cell catalyst iron phosphide nanoparticles, the method coating carbon on the surface of the iron phosphide nanoparticles in order to improve the activity and durability of the iron phosphide nanoparticles to be used as a fuel cell catalyst. Therefore, the present invention can coat carbon on the surface of iron phosphide nanoparticles while preparing the iron phosphide nanoparticles with a single heat treatment process, and can improve the durability of the iron phosphide nanoparticles by physically and chemically protecting the iron phosphide nanoparticles through the carbon coated on the surface of the iron phosphide nanoparticles.

Classes IPC  ?

• H01M 4/90 - Emploi de matériau catalytique spécifié

Abrégé

The present invention relates to a S1PR4-targeting composition for preventing or treating non-alcoholic steatohepatitis and, more particularly, to a pharmaceutical composition and a health functional food composition, both comprising a sphingolipid compound which serves as a functional inhibitor against S1PR4, showing prophylaxis and therapy of non-alcoholic steatohepatitis. The sphingolipid compound of the present invention is expected to be applied as a leading material effective for the prevention or treatment of non-alcoholic steatohepatitis (NASH) as it has the effect of reducing the infiltration of inflammatory cells into hepatic tissues and suppressing fibrosis and decreases a level of liver injury (ALT), inflammation in hepatic tissues, and the expression of a fibrosis-related gene.

Classes IPC  ?

• A61K 31/42 - Oxazoles
• A61K 31/4192 - 1,2,3-Triazoles
• A61K 31/66 - Composés du phosphore
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs

Abrégé

The present invention relates to a S1PR4-targeting composition for preventing or treating non-alcoholic steatohepatitis and, more particularly, to a pharmaceutical composition and a health functional food composition, both comprising a sphingolipid compound which serves as a functional inhibitor against S1PR4, showing prophylaxis and therapy of non-alcoholic steatohepatitis. The sphingolipid compound of the present invention is expected to be applied as a leading material effective for the prevention or treatment of non-alcoholic steatohepatitis (NASH) as it has the effect of reducing the infiltration of inflammatory cells into hepatic tissues and suppressing fibrosis and decreases a level of liver injury (ALT), inflammation in hepatic tissues, and the expression of a fibrosis-related gene.

Classes IPC  ?

• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 31/4192 - 1,2,3-Triazoles
• A61K 31/42 - Oxazoles
• A61K 31/66 - Composés du phosphore

Abrégé

Provided in the present invention is a nucleic acid extraction apparatus comprising: a first container, which includes a nanofilter having uniform nano-sized pores and provided on the lower surface thereof, can support a first liquid, and has one or more first wells comprising a first electrode immersible in the first liquid; and a second container, which can accommodate the first well, can support a second liquid, and has one or more second wells comprising a second electrode immersible in the second liquid.

Classes IPC  ?

• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

The present invention relates to a marking material having a contrasting effect and tissue adhesion characteristics and comprising core/shell nanoparticles, which are structured to comprise a core having a contrasting effect and a silica shell formed on the surface of the core, and a method for manufacturing the same. More particularly, the present invention relates to core/shell nanoparticles configured such that the core portion has a contrasting effect, and the silica shell portion has tissue adhesion characteristics, thereby giving the core/shell nanoparticles both the tissue adhesion characteristics and the contrasting effect. Therefore, according to the present invention, the nanoparticles can be utilized as a tissue adhesive and as a contrast medium, and can be used as a marking material for a real-time multi-mode image-based technology.

Classes IPC  ?

• A61K 49/00 - Préparations pour examen in vivo
• A61K 49/18 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par un aspect physique particulier, p. ex. émulsions, microcapsules, liposomes
• A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes

Abrégé

The present invention relates to a recombinant antigen protein composed of multiple epitopes in order to develop a foot-and-mouth disease subunit vaccine and a method for producing the same. A recombinant expression vector according to the present invention can mass-produce recombinant antigen proteins inexpensively and safely through microorganism culture and can be easily purified. It is confirmed that the recombinant antigen protein produced by the recombinant expression vector is composed as a multi-epitope to improve immune responses against various foot-and-mouth disease variants. Therefore, the recombinant expression vector can be advantageously used as a tool for providing a recombinant antigen protein that can be used as an effective foot-and-mouth disease subunit vaccine.

Classes IPC  ?

• A61K 39/135 - Virus de la fièvre aphteuse
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a centrifugal pump impeller including a ridge structure and, more specifically, to a centrifugal pump impeller including a ridge structure, which is capable of improving the efficiency of a centrifugal pump. The centrifugal pump impeller including the ridge structure, of the present invention, applies the ridge structure to impeller blades of the centrifugal pump, thereby having advantageous effects of minimizing the occurrence of flow separation inside the impeller and improving the efficiency of the centrifugal pump.

Classes IPC  ?

• F04D 29/24 - Aubes
• F04D 29/30 - Aubes
• F04D 29/66 - Lutte contre la cavitation, les tourbillons, le bruit, les vibrations ou phénomènes analoguesÉquilibrage

Abrégé

The graphene flake thin film manufacturing apparatus according to the present invention, which produces graphene on a substrate by using graphite powder, comprises: a substrate disposition unit having a substrate disposed at one side thereof; a nozzle unit which is in a tubular shape having an interior space so as to allow for the movement of graphite powder, has a spray hole at one side thereof, and sprays the graphite powder onto the substrate through the spray hole; and a graphite supply unit communicating with the interior space of the nozzle unit and supplying the graphite powder to the interior space. The graphene flake thin film manufacturing apparatus and graphene flake thin film manufacturing method, according to the present invention, are configured such that graphene flake thin films can be manufactured by depositing graphene on substrates by spraying graphite powder via the nozzle unit so as for same to collide with the substrates at a high speed.

Classes IPC  ?

• C01B 32/182 - Graphène
• C04B 35/52 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base de non oxydes à base de carbone, p. ex. graphite
• C04B 35/622 - Procédés de mise en formeTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques
• C04B 41/85 - Revêtement ou imprégnation avec des substances inorganiques
• C23C 24/04 - Dépôt de particules par impact

Abrégé

The present invention relates to a drug delivery system for effectively administering a drug into human (or animal) body tissue. The microjet drug delivery system provided by the present invention comprises: (a) a microjet injector comprising: a pressure chamber sealed at a part of a side surface thereof by an elastic membrane and hermetically filled with a pressure generating liquid; and a drug chamber disposed adjacent to the pressure chamber with the elastic membrane therebetween, containing a drug solution therein, and having a micro-nozzle formed at one side thereof, the micro-nozzle being provided to discharge the drug solution to the outside therethrough; (b) a laser generator, configured to generate a laser beam and emit the laser beam to the outside, for irradiating a laser beam onto the pressure generating liquid in the microjet injector to generate bubbles; and (c) a fractional laser filter module for dividing the beam incident from the laser generator into a plurality of fractional laser beams, each reduced in diameter, and for outputting the fractional laser beams. The microjet drug delivery system of the present invention as described above selectively removes the stratum corneum through a process of pre-ablating skin in advance using a fractional laser beam, and performs drug microjet injection at a site which is relatively weakened due to the removal of the stratum corneum, thereby effectively infiltrating a drug into skin tissue.

Classes IPC  ?

• A61M 5/30 - Seringues pour injection par projection, sans aiguille, p. ex. utilisables avec des ampoules ou des cartouches échangeables
• A61M 5/42 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras avec des moyens pour insensibiliser la peau, pour soulever la peau en vue de faciliter la piqûre ou pour localiser le point du corps où la piqûre doit être effectuée
• A61M 5/20 - Seringues automatiques, p. ex. avec tige de piston actionnée automatiquement, avec injection automatique de l'aiguille, à remplissage automatique
• H01S 3/16 - Matériaux solides
• G02B 27/14 - Systèmes divisant ou combinant des faisceaux fonctionnant uniquement par réflexion

Abrégé

The present invention relates to a blood pump. The blood pump according to the present invention comprises: a housing having an inlet, through which blood flows, provided at an upper part thereof and an outlet, through which the blood is discharged, provided along an edge thereof; an impeller part rotatably provided inside the housing, and having a plurality of blades provided on the surface thereof so as to move, toward the outlet by centrifugal force, the blood flowing in through the inlet; a rotary shaft member provided to pass through a center portion of the impeller part so as to support the impeller part to be rotatable, and moving the blood to a lower part thereof; and a magnetic body provided at the impeller part so as to rotate the impeller part in a predetermined direction according to a change in a magnetic field outside the housing.

Classes IPC  ?

• A61M 1/10 - Pompes pour le sang; Cœurs artificiels; Dispositifs pour aider mécaniquement la circulation, p.ex. pompes à ballon intra-aortique
• A61M 1/12 - Pompes pour le sang; Cœurs artificiels; Dispositifs pour aider mécaniquement la circulation, p.ex. pompes à ballon intra-aortique implantables dans le corps

Abrégé

The present invention relates to a bending sensor and, more specifically, to a bending sensor for measuring the bending angle of a joint in a configuration such as the joint of a robot. The bending sensor of the present invention has an effect of providing a bending sensor which has a simple structure, and thus can be manufactured at low cost, has high linearity, and can effectively measure the bending angle of an object even at a high curvature.

Classes IPC  ?

• G01B 5/30 - Dispositions pour la mesure caractérisées par l'utilisation de techniques mécaniques pour mesurer la déformation dans un solide, p. ex. indicateur de déformation mécanique
• G01B 5/24 - Dispositions pour la mesure caractérisées par l'utilisation de techniques mécaniques pour mesurer des angles ou des cônesDispositions pour la mesure caractérisées par l'utilisation de techniques mécaniques pour tester l'alignement des axes
• G01D 11/18 - Ressorts
• G01D 11/06 - Suspensions à ruban ou à fil, p. ex. en tension

Abrégé

The present invention provides a rabbit monoclonal antibody to acetylated mouse BubR1 and a preparation method therefor and, more particularly, provides the use of the monoclonal antibody in a method for measuring the activity of cell division checkpoints on the basis of a degree of acetylation of BubR1, a method for detecting a tumor disease on the basis of aberrant cell division, a method for diagnosing cancer, a method for screening anti-cancer agents, or a method for regulating a cell division cycle.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention relates to a composition for regulating cell division by promoting or inhibiting the activity of FCHo1, and a method for regulating cell division using the same. The FCHo1 activity modulator of the present invention targets FCHo1 which functions as an important factor in cell division, and promotes or inhibits the activity thereof, thereby promoting cell division or inhibiting cell division, and thus can be effectively utilized for the treatment of diseases associated with cell division.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention is to provide an underwater moving apparatus with an enhanced maneuvering performance. The underwater moving apparatus with an enhanced maneuvering performance, according to the present invention, comprises: a moving apparatus body having a propeller; a plurality of long grooves formed on an outer surface of the moving apparatus body in the longitudinal direction of the moving apparatus body; a plurality of ridges which are movably installed in the inner and outer directions by being disposed on the long grooves of the moving apparatus body in the longitudinal direction of the moving apparatus body so as to protrude from the outer surface of the moving apparatus body; a ridge driving device installed in the moving apparatus body to move the plurality of ridges so as to protrude from the outer surface of the moving apparatus body; and a controller which controls the ridge driving device to prevent flow separation in the moving apparatus body by forming an eddy flow on the outer surface of the moving apparatus body in such a manner that the ridges protrude from the outer surface of the moving apparatus body when the angle of attack of the moving apparatus body becomes greater than a certain angle during underwater movement of the moving apparatus body.

Classes IPC  ?

• B63G 8/00 - Navires submersibles, p. ex. sous-marins
• B63G 8/14 - Commande de l'assiette ou de la profondeur
• F42B 19/01 - Commandes des gouvernes

Abrégé

The present invention relates to a substrate treatment apparatus. The substrate treatment apparatus according to the present invention comprises: a chamber providing a space for treating a substrate; a support unit, provided inside the chamber, for supporting the substrate; and a nozzle for providing a cleaning medium to the substrate supported by the support unit, wherein the nozzle comprises: a contracting portion having an inlet through which the cleaning medium flows in, and having a cross-sectional area which decreases as the distance from the inlet increases; an expanding portion having a spray opening through which the cleaning medium is sprayed, and having a cross-sectional area which increases as the distance to the spray opening decreases; and an orifice located between the contracting portion and expanding portion, wherein the cleaning medium flowing into the contracting portion is a single gas.

Classes IPC  ?

• H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
• H01L 21/67 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants
• H01L 21/683 - Appareils spécialement adaptés pour la manipulation des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide pendant leur fabrication ou leur traitementAppareils spécialement adaptés pour la manipulation des plaquettes pendant la fabrication ou le traitement des dispositifs à semi-conducteurs ou des dispositifs électriques à l'état solide ou de leurs composants pour le maintien ou la préhension

Abrégé

The present invention provides RAPGEF2, IFT80, SSH2, XRCC3, SPAG17, PLEKHM2, CLEC4C, FRAS1, ADGRL3, and PSEN1 mutant genes and mutant proteins as markers for amyotrophic lateral sclerosis and a diagnostic method for amyotrophic lateral sclerosis using the same. The markers for amyotrophic lateral sclerosis of the present invention, which are new variants found in Korean ALS patients, are very rare variants with a frequency of less than 0.1% in the previously reported database or variants that have not been reported, and are variants not found in normal control groups. The mutant genes and/or the mutant proteins encoded therefrom found in the present invention can be very favorably used in establishing genetic causes of ALS and diagnosing ALS. A gene or protein test is performed on the mutant genes and/or the mutant proteins encoded therefrom found in the present invention, thereby allowing early diagnosis of amyotrophic lateral sclerosis and maximizing the therapeutic effect through the early application of an appropriate treatment method, and furthermore, enabling accurate customized treatment according to the etiological cause.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention relates to a technique for suppressing membrane biofouling on the surface of a separation membrane by immobilizing biofilm formation-suppressing microorganisms and using the same in a microorganism immobilizing container during a separation membrane water treatment process, and provides a biofilm formation-suppressing microorganism immobilizing container comprising: a non-hollow/hollow pillar-type or sheet-type transmissive carrier having mobility because of submerged aeration; and biofilm formation-suppressing microorganisms immobilized inside the carrier. In addition, the present invention provides a separation membrane water treatment device comprising: a reactor for accommodating treated water; a separation membrane module for water treatment; and the biofilm formation-suppressing microorganism immobilizing container arranged inside the reactor.

Classes IPC  ?

• C02F 3/10 - GarnissagesRemplissagesGrilles
• C02F 3/08 - Procédés aérobies utilisant des corps de contact mobiles
• C02F 3/12 - Procédés par les boues activées
• B01D 65/02 - Nettoyage ou stérilisation de membranes
• B01D 65/08 - Prévention de l'encrassement de la membrane ou de la polarisation par concentration
• C02F 1/44 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par dialyse, osmose ou osmose inverse

Abrégé

The present invention relates to a system for measuring the rotational cycle of a rotor and, more particularly, to a system for measuring the rotational cycle of a rotor, for accurately measuring the cycle and rotational phase angle of the rotor in order to evaluate measurement values of the flow field of the rotor. The system for measuring the rotational cycle of a rotor according to the present invention has an effect of allowing the rotational cycle and rotational phase of a rotor to be accurately determined regardless of the blade structure of the rotor, thereby effectively evaluating the flow field measurement data of the rotor.

Classes IPC  ?

• G01D 5/34 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c.-à-d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux les rayons lumineux étant détectés par des cellules photo-électriques
• G01V 8/14 - Détection, p. ex. en utilisant des barrières de lumière en utilisant un émetteur et un récepteur en utilisant des réflecteurs

Abrégé

A bio-sensor for detecting a specific target, according to the present embodiment, comprises: a substrate; a first electrode and a second electrode, which are arranged on the substrate so as not to be electrically connected to each other; and a probe which is arranged on the substrate, the first electrode, and the second electrode, and couples with a target.

Classes IPC  ?

• G01N 27/327 - Électrodes biochimiques
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

The present invention relates a catalyst for water splitting and a method for preparing the same and, more specifically, to a catalyst for water splitting composed of: at least one transition metal selected from the group consisting of Mn, Fe, Co, Ni, an Cu; and a silicon-containing oxide or hydroxide, the catalyst being amorphous, and to a method for preparing a catalyst for water splitting.

Classes IPC  ?

• B01J 21/06 - Silicium, titane, zirconium ou hafniumLeurs oxydes ou hydroxydes
• B01J 23/34 - Manganèse
• B01J 23/70 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe du cuivre ou des métaux du groupe du fer
• B01J 37/03 - PrécipitationCo-précipitation

Abrégé

The present invention relates to a resource circulation type restroom and, specifically, to a restroom separating feces and urine, storing the same, and then composting the same. The present invention comprises: a toilet having a bowl; a conveyor provided at the lower end of the toilet; a liquid fertilizer producing tank for producing liquid fertilizer from the urine transferred by the conveyor; and a conveyor washing device for spraying the urine, which was changed into the liquid fertilizer in the liquid fertilizer producing tank, at a moving means including the toilet and/or the conveyor. Therefore, the present invention separates feces and urine, composts the feces between the separated feces and urine, and produces the liquid fertilizer from the urine, thereby recycling the feces and urine. In addition, the present invention does not use water since the urine is changed into the liquid fertilizer, and then the liquid fertilizer is used to wash the moving means. Furthermore, the present invention can effectively separate the feces and the urine through the conveyor. Moreover, the present invention can increase the efficiency of producing the liquid fertilizer from the urine since a partition is provided in the liquid fertilizer producing tank such that the urine moves by flowing over the partition.

Classes IPC  ?

• A47K 11/02 - Cabinets fonctionnant à sec, p. ex. cabinets avec incinération
• C05F 3/06 - Appareillage pour leur fabrication
• C05F 3/04 - Engrais fabriqués à partir des excréments humains ou animaux, y compris le fumier à partir des fèces

Abrégé

The present invention provides a Pvr4 gene having resistance to potyvirus and a use thereof. The present invention can contribute to the breeding of potyvirus-resistant chili peppers by using a molecular marker using a Pvr4 gene sequence. In addition, the present invention can transform potatoes or tomatoes, as heterogeneous crops, showing, economically, an enormous reduction in production due to potyvirus, and an increased crop yield and an economical effect can be expected through such a transformation.

Classes IPC  ?

• C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
• C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
• C07K 16/16 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de végétaux
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques

Abrégé

An image information collecting system comprises: a position transmitting device for transmitting first position information indicating a position of the image information collecting system itself; a plurality of cameras for collecting image data, storing the image data in a storage medium of the image information collecting system itself, generating data identification information including oriented direction information of a camera and time information at a time point at which the image data has been collected, and transmitting the data identification information through a network; and a service server for receiving the first position information and the data identification information, and determining whether a target camera for photographing a current position of the position transmitting device exists among the plurality of cameras, using the data identification information and second position information indicating positions of the plurality of cameras.

Classes IPC  ?

• G08B 13/196 - Déclenchement influencé par la chaleur, la lumière, ou les radiations de longueur d'onde plus courteDéclenchement par introduction de sources de chaleur, de lumière, ou de radiations de longueur d'onde plus courte utilisant des systèmes détecteurs de radiations passifs utilisant des systèmes de balayage et de comparaison d'image utilisant des caméras de télévision

Abrégé

Disclosed are: a method for controlling the resistance of a plant to environmental stress, comprising a step of transforming plant cells with a recombinant vector including a gene coding for a rice-derived Oryza sativa Aux/IAA 6 (OsIAA6) protein; a method for producing a transgenic plant body of which the resistance of a plant to environmental stress is controlled, comprising a step of transforming plant cells with the recombinant vector including a gene coding for the OsIAA6 protein; a transgenic plant body produced by the method and of which the resistance to environmental stress is controlled; and seeds thereof.

Classes IPC  ?

• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
• A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique

Abrégé

The present invention relates to a portable toilet and, specifically, to a portable toilet combined with an excrement separation device. The present invention facilitates transportation since a body thereof has a box shape but is folded prior to assembly. In addition, the present invention can prevent feces inside the body from being seen by forming an inclined plane inside the body. Moreover, the present invention comprises an area separation bar inside the body and allows an excrement bag to be hung over the area separation bar, thereby allowing excrement to be stored in a separated manner rather than allowing excrement to be stored in a combined manner in the excrement bag. Furthermore, the present invention comprises, in advance, a solidifying agent in the urine storage area of the excrement bag, thereby enabling urine to be received several times in one excrement bag.

Classes IPC  ?

• A47K 11/02 - Cabinets fonctionnant à sec, p. ex. cabinets avec incinération

Abrégé

The present invention relates to graphene and, particularly, to a method for doping graphene using substrate surface modification, a method for manufacturing a graphene composite electrode using graphene and inorganic matter, and a graphene structure comprising the same. The method for doping graphene according to an embodiment of the present invention may comprise the steps of: forming, on a substrate, a precursor polymer layer for doping; and positioning graphene on the substrate on which the precursor polymer layer is formed. In addition, the method for manufacturing a graphene composite electrode according to an embodiment of the present invention may comprise the steps of: forming graphene on catalyst metal; forming a transparent conductive oxide on the graphene; crystallizing the transparent conductive oxide by applying heat of 150 °C or higher; and transferring, to a final substrate, a composite electrode consisting of the graphene and the transparent conductive oxide.

Classes IPC  ?

• C01B 31/04 - Graphite
• C23C 16/26 - Dépôt uniquement de carbone
• H01L 21/283 - Dépôt de matériaux conducteurs ou isolants pour les électrodes
• H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée

Abrégé

The present invention relates to a rainwater collecting facility and a moving-type rainwater storage tank and a system for moving rainwater on water, and especially, to a rainwater collecting facility and a moving-type rainwater storage tank and a system for moving rainwater on water enabling rainwater to be collected by the rainwater collecting facility, transferred on water, and then used in a place of use by floating same on water.

Classes IPC  ?

• E03B 3/02 - Procédés ou installations pour obtenir ou recueillir de l'eau potable ou de l'eau courante à partir d'eau de pluie

Abrégé

The present invention relates to a transformable transport device and a joint module provided therein, the transformable transport device comprising: a main frame having opposite ends that are in communication with each other; a guide frame that has a specified length such that the main frame is mounted thereon, wherein the main frame moves to a specified position on the guide frame and is fixed to the specified position; a joint module detachably coupled to the main frame such that the angle of the joint module relative to the main frame is adjusted; a plurality of front-side units, each of which includes a front-side wheel and is selectively detachably coupled to one end portion of the guide frame; and rear-side units selectively detachably coupled to opposite end portions of the joint module so as to be rotatable, each rear-side unit comprising one or more rear-side wheels. As such, the transformable transport device can implement a plurality of transport means, which can be used from infancy to adolescence, with a single device.

Classes IPC  ?

• B62K 13/00 - Cycles convertibles ou transformables en un autre type de cycle ou de véhicule terrestre
• B62K 17/00 - Cycles non prévus ailleurs
• B62B 7/12 - Voitures d'enfants Poussettes, p. ex. poussettes pour poupées à plus d'un essieuDispositifs de direction à cet effet transformables, p. ex. en pièce de mobilier ou jouet pour enfants
• B62K 9/02 - Tricycles

Abrégé

The present invention relates to biodegradable magnesium and a method for preparing the same. The biodegradable magnesium according to the present invention is characterized in that the biodegradation rate of the biodegradable magnesium is controlled using a difference in atom packaging density.

Classes IPC  ?

• A61L 27/04 - Métaux ou alliages

Abrégé

A sound data processing system according to the present embodiment is a system comprising a plurality of sound collecting terminals, a plurality of sound providing terminals, and a server, each sound collecting terminal and sound providing terminal, from among the plurality of sound collecting terminals and sound providing terminals, comprising: a sound collecting means for collecting sounds with location and orientation direction; a sound providing means for providing sounds with location and orientation direction; a location detection means for detecting the location of the sound collecting means and sound providing means; a direction detection means for detecting a orientation direction; supplementary data comprising location data corresponding to the location detected by the location detection means, and orientation direction data corresponding to the orientation direction detected by the direction detection means; and a communication module for transmitting, via the network, sound data corresponding to the sound collected by the sound collection means.

Classes IPC  ?

• H04R 3/00 - Circuits pour transducteurs
• H04R 1/40 - Dispositions pour obtenir la fréquence désirée ou les caractéristiques directionnelles pour obtenir la caractéristique directionnelle désirée uniquement en combinant plusieurs transducteurs identiques

Abrégé

Disclosed are T-ALT 1 and 2 elements acting on an alternative-lengthening-of-telomeres mechanism, and a use thereof. According to the present application, the elements can be used as a marker for detecting intracellular ALT activity or can be useful for screening for a material, and the like, for a cancer therapeutic agent.

Classes IPC  ?

• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet

Abrégé

One embodiment provides a technique of adjusting a gate voltage to be applied to at least one MOS capacitor and an amount of electric charges to be stored in the MOS capacitor so as to determine sensitivity of a change in the amount of electric charges stored in the MOS capacitor, and exposing the MOS capacitor to an electric filed for a predetermined amount of time and then reading an electron inflow or outflow result due to the electric field so as to interpret the intensity and the direction of the electric field, thereby measuring the intensity and the direction of the electric field.

Classes IPC  ?

• G01R 29/12 - Mesure du champ électrostatique
• G01R 29/08 - Mesure des caractéristiques du champ électromagnétique

Abrégé

The present invention provides a hierarchical microstructure having a novel structure, and a manufacturing method for a mold for manufacturing the same. A mold for forming a hierarchical microstructure, manufactured by the manufacturing method, can form a microstructure having various hierarchical structures, for example, a micro/nano dual structure and a base/bridge dual structure, using a simple process, and can form a microstructure up to the bottom surface of each layer, thereby forming a hierarchical microstructure having a larger specific surface area. The present invention can be applied to various fields, such as surface treatment of a large moving means, a functional material having ultra hydrophobicity, an industrial robot, and an electronic element, in which such a microstructure having a multiscale is used.

Classes IPC  ?

• B81B 1/00 - Dispositifs sans éléments mobiles ou flexibles, p. ex. dispositifs capillaires microscopiques
• G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet

Abrégé

The present invention relates to a new biomarker and, more particularly, to a sorafenib reactive prediction kit for a liver cancer patient, the kit containing, as an effective ingredient, a probe molecule which can detect EDN1 protein within a sample or the level of mRNA encoding the EDN1 protein.

Classes IPC  ?

• G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention presents a novel prediction model for calculating a periodontal disease prediction score and provides a system and a method therefor. Unlike conventional technology, the prediction model is obtained by taking into consideration all of social and economic habit factors, molecular and biological factors and whole-body health factors, and a verification result diagnosis ability thereof has been confirmed to be excellent.

Classes IPC  ?

• G06F 19/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des applications spécifiques (spécialement adaptés à des fonctions spécifiques G06F 17/00;systèmes ou méthodes de traitement de données spécialement adaptés à des fins administratives, commerciales, financières, de gestion, de surveillance ou de prévision G06Q;informatique médicale G16H)

Abrégé

A system for collecting event data comprises: a plurality of cameras, each of which collects image data and stores the image data on a storage medium, generates data identification information including at least one information from among the group including time information on when the image data was collected, location information on where the image data was collected, and orientation information of a camera, and transmits periodically, or at a specific point of time, the data identification information via a wired or wireless network; and a service server which determines, among the plurality of cameras, at least one target camera storing image data related to a specific event by using the data identification information and event information including the time and location when and where the event occurred, and receives image data related to the event from the target camera.

Classes IPC  ?

• G06Q 50/10 - Services
• G08B 13/196 - Déclenchement influencé par la chaleur, la lumière, ou les radiations de longueur d'onde plus courteDéclenchement par introduction de sources de chaleur, de lumière, ou de radiations de longueur d'onde plus courte utilisant des systèmes détecteurs de radiations passifs utilisant des systèmes de balayage et de comparaison d'image utilisant des caméras de télévision

Abrégé

The present invention relates to a method and an apparatus for estimating multiple-ranking using pairwise comparative data, the method according to one embodiment comprising the steps of: inputting information for pairwise comparative data as input; and generating multiple-ranking data on the basis of the input data, wherein the input data comprises a collection of a plurality of respondents, a collection of a plurality of items, and a collection of a plurality of pairwise comparative data for the plurality of items, and each item of pairwise comparative data in the plurality of same is data indicating the preference between two items determined in accordance with an evaluation criterion from among a plurality of evaluation criteria.

Classes IPC  ?

• G06F 17/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des fonctions spécifiques

Abrégé

The present invention provides a technique of minimizing traffic and time required for restoring an original file in a file management apparatus for restoring an original file from a plurality of storage devices. The file management method of the present invention comprises the steps of: selecting, from among a plurality of storage devices, storage devices that will receive file fragments; determining scheduling information indicating the file fragments to be received from the selected storage devices according to the communication speed between the file management apparatus and the selected storage devices; receiving the file fragments from each of the selected storage devices by referencing the determined scheduling information; and generating a restored file from the received file fragments.

Classes IPC  ?

• G06F 11/08 - Détection ou correction d'erreur par introduction de redondance dans la représentation des données, p. ex. en utilisant des codes de contrôle

Abrégé

The present invention relates to a fluorescence sensor capable of real-time imaging for measuring a cellular thiol level. The present invention reveals that the fluorescence intensity of the fluorescent real-time SH group-tracer (FreSH-Tracer) of the present invention increases or decreases continuously, ratiometrically or reversibly depending on the thiol level in living cells, and thus can be usefully used as a biosensor which is remarkably susceptible to quantitative or qualitative real-time detection of the cellular thiol level in living cells.

Classes IPC  ?

• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
• G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur

Abrégé

The present invention relates to a file distribution management apparatus and method for managing files so that predetermined file fragments are generated using a given file, and an initial file can be restored from a predetermined number of files or more but cannot be restored from less than a predetermined number of files among the file fragments. In addition, the present invention enhances security by shuffling the order of original files when the file fragments are generated. In a method for shuffling the order of the original files according to one embodiment of the present invention, the order of the original files is shuffled by a block unit, and the size of a block can be randomly selected by a user. Further, the file fragments are formed by generating a plurality of segments from the original files, and the sizes of the plurality of segments have a constant ratio or an arbitrary value.

Classes IPC  ?

• G06F 15/16 - Associations de plusieurs calculateurs numériques comportant chacun au moins une unité arithmétique, une unité programme et un registre, p. ex. pour le traitement simultané de plusieurs programmes

Abrégé

The present invention relates to an organic compound used as an electron acceptor and a preparation method for same. An organic compound used as an electron acceptor, according to an embodiment of the present invention, is represented by the following chemical formula (1) (chemical formula (1)), wherein Ar1 is one of the structures shown in the following chemical formula (2) (chemical formula (2)) and Ar2 is one of the structures shown in the following chemical formula (3) (chemical formula (3)).

Classes IPC  ?

• C07D 409/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
• C07D 409/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
• H01L 51/42 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement

Abrégé

The present invention is for the purpose of installing a wireless transmitter in a transmitting unit of a bioelectric signal measuring device and changing electrodes to be attachable/detachable in order to: prevent the usable distance of the bioelectric signal measuring device from being restricted by limitations in the length of electric wire between a transmitter and a receiver, prevent the electric wire impeding an operation by blocking the field of vision during the operation, and reduce the danger of a disconnected electric wire. The present invention provides a bioelectric signal measuring device comprising: an insulation film capable of being attached to the outer peripheral surface of a bio catheter that is inserted into an opening of the human body; a plurality of thin film electrodes arranged to contact muscle or nerve regions at which a portion of the bio catheter is located; a transmitter for wirelessly transmitting a bioelectric signal scanned by the thin film electrodes; conductive wire electrically connecting the thin film electrodes to the transmitter; and a battery for operating the transmitter, wherein the electrodes, the transmitter, the conductive wire, and the battery are disposed on the insulation film. Also provided is a bioelectric signal measuring device configured of a head portion having a broad surface area and a tail portion connected to the head portion, the device comprising: an insulation film capable of being attached along the length of a bio catheter that is inserted into the human body; a plurality of thin film electrodes disposed on the head portion that is the opposite surface to the insulation film attached on the bio catheter, and arranged to contact muscle or nerve regions at which a portion of the bio catheter is located; and conductive wire located on the tail portion of the insulation film, and having one end electrically connected to the thin film electrodes and the other end connected to the terminal end of the tail portion.

Classes IPC  ?

• A61B 5/04 - Mesure de signaux bioélectriques du corps ou de parties de celui-ci
• A61B 5/0488 - Electromyographie
• A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
• A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)

Abrégé

The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for preventing or treating a metabolic disease, and a functional food composition for alleviating or mitigating a metabolic disease using the same. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid level, and blood sugar, improves a blood liver function index, and suppresses metabolic inflammation responses, and thus, ultimately, can be favorably used as a pharmaceutical composition or a functional food composition, which exhibits activity to prevent or treat a metabolic disease selected from the group consisting of obesity, diabetes, abnormal hypertriglyceridemia, fatty liver, and insulin resistance syndrome.

Classes IPC  ?

• C07D 211/32 - Composés hétérocycliques contenant des cycles pyridiques hydrogénés, non condensés avec d'autres cycles avec uniquement des atomes d'hydrogène et de carbone liés directement à l'atome d'azote du cycle ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle avec des radicaux hydrocarbonés substitués liés aux atomes de carbone du cycle avec des radicaux hydrocarbonés, substitués par des atomes d'oxygène ou de soufre liés par des liaisons doubles ou par deux atomes d'oxygène ou de soufre, liés au même atome de carbone par des liaisons simples par des atomes d'oxygène
• C07D 211/06 - Composés hétérocycliques contenant des cycles pyridiques hydrogénés, non condensés avec d'autres cycles avec uniquement des atomes d'hydrogène et de carbone liés directement à l'atome d'azote du cycle ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
• A61K 31/445 - Pipéridines non condensées, p. ex. pipérocaïne
• A61P 3/04 - AnorexigènesMédicaments de l'obésité

Abrégé

Disclosed are mesenchymal stem cells overexpressing Oct4 and Sox2 and a use thereof as a cell therapeutic agent. The mesenchymal stem cells overexpressing Oct4 and Sox2 according to the present invention have outstandingly improved proliferation ability and an ability to differentiate into fat cells, bone cells and hepatocytes, and particularly are used in the treatment of chronic liver diseases such as liver cirrhosis, so that liver functions damaged by liver diseases can be improved and a regeneration-promoting effect can be expected.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
• A61K 35/32 - OsOstéocytesOstéoblastesTendonsTénocytesDentsOdontoblastesCartilageChondrocytesMembrane synoviale
• A61K 35/407 - FoieHépatocytes

Abrégé

A field-programmable analog array according to an embodiment of the present invention comprises an array of a plurality of programmable analog timing circuits, the field-programmable analog array being field-programmable to a plurality of analog or analog-to-digital conversion circuits, such as relaxation oscillators, phase shifters, phase interpolators, pulse width modulators, pseudo index digitally controlled oscillators, etc. through programming, without physical circuit re-processing. Further, a field-programmable mixed signal array according to an embodiment of the present invention comprises a plurality of field-programmable analog arrays, field-programmable digital blocks and field-programmable connecting wire blocks, the field-programmable mixed signal array being field-programmable to a plurality of analog, digital or analog-to-digital conversion circuits, such as digital pulse width modulators, time-digital converters, analog-digital converters, phase locked loops, DC-DC, AC-DC and DC-AC converters, etc. through programming, without physical circuit re-processing.

Classes IPC  ?

• H03K 19/177 - Circuits logiques, c.-à-d. ayant au moins deux entrées agissant sur une sortieCircuits d'inversion utilisant des éléments spécifiés utilisant des circuits logiques élémentaires comme composants disposés sous forme matricielle

Abrégé

The present invention relates to an adsorbent comprising silica nanoparticles with corrugated surfaces, and to a method for preparing the same, wherein the adsorbent can easily adsorb an adsorption material and can selectively adsorb a particular material.

Classes IPC  ?

• B01J 20/10 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant de la silice ou un silicate
• B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
• B01J 20/32 - Imprégnation ou revêtement
• C01B 33/12 - SiliceSes hydrates, p. ex. acide silicique lépidoïque

Abrégé

The present invention relates to a method for preparing titanium by using electrowinning and, more specifically, to a method for preparing titanium by using electrowinning, comprising the steps of: preparing a mixture by mixing a solid electrolyte, which contains an oxide of the group 1 elements and boron oxide, and titanium dioxide; and forming a molten oxide from the mixture by putting the mixture in an electrowinning apparatus comprising an anode and an insoluble cathode and heating the same, and then forming titanium on the cathode by applying voltage to the anode and the cathode.

Classes IPC  ?

• C25C 3/26 - Production, récupération ou affinage électrolytique de métaux par électrolyse de bains fondus du titane, du zirconium, de l'hafnium, du tantale ou du vanadium
• C25C 7/02 - ÉlectrodesLeurs connexions
• C25C 7/06 - Conduite ou entretien

Abrégé

According to an aspect, provided is an organic light-emitting element comprising a first electrode, a second electrode facing the first electrode, and a light-emitting layer interposed between the first and second electrodes, the light-emitting layer comprising a host and a dopant. The dopant is a heteroleptic iridium complex having a transition dipole moment, the horizontal orientation ratio of which is, with regard to a plane of the light-emitting layer, 75% to 100%.

Classes IPC  ?

• C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
• H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)
• H01L 51/52 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED) - Détails des dispositifs

Abrégé

A joint movement assistance device is disclosed. The present device comprises: a sensor part for measuring the biological information of a user; a joint fixing part fixed to a joint part of the user; a first fixing part connected to one side of the joint fixing part through a wire; a second fixing part disposed in the opposite direction of one side of the joint fixing part and connected to the joint fixing part; a power part for providing power for a joint movement of the user by providing the power to the wire; and a control part for determining intended motions of the user on the basis of the biological information measured by the sensor part, and controlling the power part regulating the power applied to the wire. Therefore, user convenience can be improved.

Classes IPC  ?

• A61H 3/00 - Appareils pour aider des personnes handicapées à marcher
• A61F 5/052 - Dispositifs pour étirer ou réduire les membres fracturésDispositifs pour tractionÉclisses pour l'immobilisation spécialement adaptés pour faciliter la marche, p. ex. attelles ambulatoires

Abrégé

The present disclosure relates to a method for message flooding in a wireless communication system, and is characterized in that it includes the steps of: broadcasting, by a transmission node, a flooding message to a surrounding node through a first common channel; checking, by a reception node, whether the first common channel has received the flooding message; transmitting, by the reception node, an ACK signal through a second common channel or a NACK signal through a third common channel, based on a result of the check; and determining, by the transmission node, whether the second common channel or the third common channel has detected a signal, to determine whether to re-transmit the flooding message.

Classes IPC  ?

• H04W 28/04 - Détection d’erreurs
• H04W 40/02 - Sélection d'itinéraire ou de voie de communication, p. ex. routage basé sur l'énergie disponible ou le chemin le plus court

Abrégé

Disclosed is a positioning method for estimating a location in a wireless communication system, the method characterized by comprising the steps of: a first terminal transmitting a positioning request message for positioning to a base station; the base station transmitting, to neighboring terminals within a cell, an anchor request message to find terminals which can be a second terminal; the base station receiving, from at least one terminal from among the neighboring terminals in the cell, an anchor response message corresponding to the response for the anchor request message; and the base station determining the second terminal on the basis of the received anchor response message.

Classes IPC  ?

• H04W 64/00 - Localisation d'utilisateurs ou de terminaux pour la gestion du réseau, p. ex. gestion de la mobilité

Abrégé

Disclosed are a method for controlling power and an apparatus therefor in a wireless communication system supporting device-to-device (D2D) communication. Specifically, a method for a terminal for controlling the transmission power of a physical sidelink discovery channel (PSDCH) in a wireless communication system supporting D2D communication comprises the steps of: calculating the sum of reception strengths of the total number of PSDCHs received from a set PSDCH reception period; and transmitting the PSDCH, wherein if the sum of reception strengths of the total number of PSDCHs is greater than a previously set threshold value, then the PSDCH to be transmitted is transmitted under the transmission power controlled by the terminal, and if the sum of reception strengths of the total number of PSDCHs is less than a previously set threshold value, then the PSDCH to be transmitted can be transmitted under the maximum transmission power.

Classes IPC  ?

• H04W 52/24 - Commande de puissance d'émission [TPC Transmission power control] le TPC étant effectué selon des paramètres spécifiques utilisant le rapport signal sur parasite [SIR Signal to Interference Ratio] ou d'autres paramètres de trajet sans fil
• H04W 52/34 - Gestion du TPC, c.-à-d. partage de la quantité limitée de puissance entre les utilisateurs ou les canaux ou encore les types de données, p. ex. charge des cellules

Abrégé

The present invention relates to a siRNA molecule having improved specificity for inhibiting target gene expression and a decreased off-target effect, the siRNA molecule having a structure of asymmetric 3'-overhangs and consisting of sense and antisense strands, wherein one of the two strands has 3'-overhangs consisting of DNA of 1 to 3 nucleotides and the other has 3'-overhangs consisting of RNA of 1 to 3 nucleotides.

Classes IPC  ?

• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens

Abrégé

The present invention relates to a poly-γ-glutamic acid derivative, which is amphiphilic, and nanoparticles based on the same. The water dispersibility and oxidative stability of an encapsulating material can be improved by encapsulating a fat-soluble vitamin or a poorly soluble drug in the nanoparticles of the present invention, and the effective application of the encapsulating material can be achieved by using, in cosmetics or medicine, nanoparticles in which the encapsulating material is encapsulated.

Classes IPC  ?

• C08G 69/10 - Polyamides dérivés, soit des acides amino-carboxyliques, soit de polyamines et d'acides polycarboxyliques dérivés d'acides aminocarboxyliques d'acides alpha-aminocarboxyliques
• C08L 77/04 - Polyamides dérivés des acides alpha-aminocarboxyliques
• C08J 3/12 - Pulvérisation ou granulation
• A61K 9/16 - AgglomérésGranulésMicrobilles

Abrégé

The present invention relates to a composition for promoting the differentiation of myoblasts, the composition containing butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition for preventing or treating muscular weakness-related diseases; a food composition for preventing or alleviating muscular weakness-related diseases; a composition for strengthening muscular strength; and a feed or feed composition for strengthening muscular strength. Furthermore, the present invention relates to a method for promoting the differentiation of myoblasts using butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof; a method for manufacturing differentiated myoblasts; and a method for treating muscular weakness-related diseases.

Classes IPC  ?

• A61K 31/4425 - Dérivés de pyridinium, p. ex. pralidoxime, pyridostigmine
• A61K 31/435 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire

Abrégé

The present invention relates to a medium composition for inducing the differentiation into insulin-producing cells, the composition containing glucosamine; a method for inducing the differentiation into insulin-producing cells by using the medium composition, and a cell therapeutic agent for treating diabetes, containing insulin-producing cells prepared by the method. The glucosamine according to the present invention can effectively induce the differentiation into insulin-producing cells through the regulation of sugar metabolism. The induction of the differentiation into insulin-producing cells using glucosamine as described above has advantages of being safe due to the exclusion of genetic manipulation; being performed at low cost since high-priced compounds or growth factors with unidentified mechanisms are not required; and minimizing cell contamination and deformation, which are caused at the time of ex vivo manipulation, due to the induction in a short period of time.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• C12N 5/074 - Cellules souches adultes
• A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques

Abrégé

Disclosed are: a method for labeling exosomes with a radioactive substance using amine groups on surfaces of the exosomes; exosomes prepared thereby; an imaging composition comprising the same; and an imaging method. According to the method of the present application, the exosomes can be stably labeled at high labeling efficiency, and the exosomes prepared by the method of the present application can be favorably used as an agent for nuclear medicine imaging and therapeutic imaging for confirming the biological distribution of exosomes and the migration or not of exosomes to target organs and target diseases in animals including a human being.

Classes IPC  ?

• G01N 33/60 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées faisant intervenir des substances marquées radioactives
• G01N 33/534 - Production de composés immunochimiques marqués avec un marqueur radioactif
• G01N 23/00 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou
• A61K 51/00 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo

Abrégé

The present invention relates to a core-shell nanocomposite including fluorescent bodies disposed to have a uniform distance in a perpendicular direction from a surface thereof, to a method of manufacturing same, and to a use for a probe for metal-enhanced fluorescence.

Classes IPC  ?

• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension
• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées

Abrégé

A wireless transmitter according to the present embodiment comprises: a piezoelectric element for generating energy when pressure is applied thereto; a charging-discharging unit for charging the energy generated by the piezoelectric element and discharges the charged energy, wherein the energy is discharged to an energy discharge path different from an energy charging path; and a wireless transmission unit receiving the energy from the charging-discharging unit so as to transmit a predetermined code, wherein the charging-discharging unit includes a plurality of capacitors connected in series so as to charge electric energy applied by the piezoelectric element, and connected in parallel so as to discharge the charged electric energy.

Classes IPC  ?

• H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
• H02N 2/18 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction fournissant une sortie électrique à partir d'une entrée mécanique, p. ex. générateurs
• H04B 1/02 - Émetteurs

Abrégé

A system for detecting a surrounding moving object using cooperative communication according to the present specification comprises: a sensing unit which has at least one sensor and detects moving objects located within the detection range of the sensor to generate sensing information; a communication unit which transmits first local measurement information indicative of traffic information of the moving objects generated on the basis of the sensing information to the outside and receives at least one second local measurement information from the outside; and a convergence processing unit which combines pre-generated extension measurement information, the first local measurement information, and the second local measurement information so as to generate new extension measurement information containing traffic information of the extension measurement information, traffic information of the first local measurement information, and traffic information of the second local measurement information.

Classes IPC  ?

• G01S 19/05 - Éléments coopérantsInteraction ou communication entre les différents éléments coopérants ou entre les éléments coopérants et les récepteurs fournissant des données d'assistance
• G01S 5/02 - Localisation par coordination de plusieurs déterminations de direction ou de ligne de positionLocalisation par coordination de plusieurs déterminations de distance utilisant les ondes radioélectriques

Abrégé

Disclosed is a vaccine composition for Orientia tsutsugamushi. Specifically, disclosed is a vaccine composition using, as an active ingredient, ScaA, which is an autotransporter protein, or the passenger domain region thereof.

Classes IPC  ?

• A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 31/00 - Agents anti-infectieux, c.-à-d. antibiotiques, antiseptiques, chimiothérapeutiques

Abrégé

The present invention relates to a method in which lipid and DOPA are synthesized with 6-arm PEG, DOPA is synthesized with gelatin, the lipid solubility of lipid is used and thereby lipid is induced to interfere and bind between surface cell phospholipid layers of the pancreatic islet of a pig, and by using a covalent bond between DOPA and SH the surface of a pancreatic islet membrane of a pig is modified through a bond between 6-arm PEG-SH, DOPA, gelatin-DOPA and linear PEG-SH. The present invention, compared to a pure pancreatic islet that has not been given any treatment, does not show changes in pancreatic islet shape, insulin secretion and cell survivability, and by confirming the increasing of maintenance time for blood glucose concentration, stability and viability of pancreatic islet can be enhanced, thereby being effectively used in a pancreatic islet transplant.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• A61L 27/38 - Cellules animales

Abrégé

The present invention, with respect to implementing a device that is capable of being reconfigured, has significantly increased the degree of integration over existing devices that are capable of being reconfigured and have the same functions by configuring a separate upper gate and lower gate, and is able to reduce dynamic parasitic components during reconfiguring-capable circuit operations and reduce wiring complexity, on the basis of a separate lower electrode array inside the device and having a built-in nonvolatile memory function, so as to ultimately be a configuration that is capable of reducing power consumption. Also, a device is provided that shows superiority over existing devices that are capable of being reconfigured in terms of various characteristics, such as function diversity in a multifunctional device, alignment tolerances during manufacturing processes, minimum electronic doping forming ability within channels, compatibility with upstream and downstream methods of manufacturing processing, and compatibility with 1D and 2D materials.

Classes IPC  ?

• H01L 27/115 - Mémoires mortes programmables électriquement; Procédés de fabrication à étapes multiples de ces dispositifs
• H01L 21/8247 - Structures de mémoires mortes (ROM) programmables électriquement (EPROM)
• H01L 21/31 - Traitement des corps semi-conducteurs en utilisant des procédés ou des appareils non couverts par les groupes pour former des couches isolantes en surface, p. ex. pour masquer ou en utilisant des techniques photolithographiquesPost-traitement de ces couchesEmploi de matériaux spécifiés pour ces couches

Abrégé

Disclosed is a technique capable of effectively estimating a three-dimensional location of a target node without requiring additional hardware through a geometric access by using location information of three anchor nodes. The height of a tetrahedron is calculated by calculating the volume of the tetrahedron and the area of the base plane thereof formed by three estimated distances between the three anchor nodes and the target node and by distances between the three anchor nodes. Projected estimated distances, obtained by projecting the estimated distances on a plane (H) formed by the three anchor nodes, and coordinate values of the three anchor nodes converted on a second coordinate system of the plane (H) are obtained, and then trilateration is performed using the projected estimated distances and the converted coordinate values so as to calculate an estimated location, projected on the plane (H), of the target node. A coordinate value of the calculated estimated location is converted into a coordinate value on a first coordinate system and then the height of the tetrahedron is reflected thereto so as to obtain a coordinate value of the three-dimensional estimated location of the target node. The number of required anchor nodes and the complexity of a positioning system can be decreased, calculating positioning information can be significantly simplified, and accuracy can be increased.

Classes IPC  ?

• G01S 5/14 - Localisation par coordination de plusieurs déterminations de direction ou de ligne de positionLocalisation par coordination de plusieurs déterminations de distance utilisant les ondes radioélectriques déterminant des distances absolues à partir de plusieurs points espacés d'emplacement connu
• H04W 64/00 - Localisation d'utilisateurs ou de terminaux pour la gestion du réseau, p. ex. gestion de la mobilité

Abrégé

Provided is a method for producing graphene-based nano carbon fiber using inter-layer self-assembly. A method for producing graphene-based nano carbon fiber using inter-layer self-assembly according to one embodiment of the present invention comprises the steps of: providing oxidated nano carbon; and discharging an oxidated nano carbon dispersion solution into a coagulation bath including polyamine to produce an oxidated nano carbon gel fiber which is crosslinked by the polyamine.

Classes IPC  ?

• D06M 11/74 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec du carbone ou du graphiteTraitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec des carburesTraitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés avec des acides graphitiques ou leurs sels
• D01D 5/00 - Formation des filaments, fils ou similaires

Abrégé

The present invention relates to: a method for increasing the resistance of a plant to drought stress, the method comprising a step of genetically transforming, into a plant cell, a recombinant vector comprising rice(Oryza sativa)-derived miR399f (microRNA 399f) precursor DNA, and over-expressing the OsmiR399f precursor; a production method for a transgenic plant having increased resistance to drought stress as compared with the wild type, by genetically transforming, into a plant cell, the recombinant vector comprising the OsmiR399f precursor DNA; and a composition for increasing the resistance of a plant to drought stress, the composition comprising a transgenic plant produced by means of the above method, and seeds thereof and the OsmiR399f precursor DNA as active ingredients.

Classes IPC  ?

• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
• A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique

Abrégé

The present invention relates to a Raman analysis method and device for high-speed quantitative analysis of a wide-area sample which enable high-speed quantitative analysis of a plurality of search targets existing in a wide-area sample while reducing the size and cost of equipment. Unlike the conventional spot-unit-based analysis, the present invention has such effects as highly improving the speed of multidimensional multiple marker analysis by reading-out continuous spectrum information on one or more consecutive scanning intervals during one camera operation period, thus reducing the noise created by the camera operation and enhancing the scanning speed.

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman
• G01N 21/55 - Réflexion spéculaire
• G01J 3/28 - Étude du spectre

Abrégé

A PoP nanostructure comprises a first nanoparticle loading a drug, and second nanoparticles surrounding a surface of the first nanoparticle and coated with protein alpha-synuclein. The protein alpha-synuclein enables the conjugation of nanoparticles and the control of drug release.

Classes IPC  ?

• A61K 9/16 - AgglomérésGranulésMicrobilles
• A61K 47/02 - Composés inorganiques
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine

Abrégé

The present invention relates to a composition for inducing differentiation of stem cells into muscular cells and a pharmaceutical composition for preventing or treating muscle damage diseases. The present invention induces the specific differentiation of stem cells into muscular cells very efficiently by using the so-far-unknown histone deacetylase 6 (HDAC6) as a new differentiation regulation target. The present invention can be favorably used to prevent or treat various muscle damage diseases, such as muscular dystrophy, muscular inflammation, and fibrosis, by regenerating lost muscular tissues.

Classes IPC  ?

• C12N 5/02 - Propagation de cellules individuelles ou de cellules en suspensionLeur conservationMilieux de culture à cet effet
• C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires

Abrégé

Disclosed are a gene packaging method using ultrasonic waves and an apparatus for implementing the same. The gene packaging method comprises the steps of: holding a solution containing a gene; determining ultrasonic irradiation conditions including the intensity and time of ultrasonic waves to be irradiated depending on the amount and length of the gene contained in the solution; and irradiating ultrasonic waves, corresponding to the ultrasonic wave irradiation conditions, to the solution such that the gene is wound or folded by radiation force to have a changed shape. Therefore, the cell transduction rate or delivery efficiency of the gene is improved, and thus the effect of the gene on disease treatment can be improved.

Classes IPC  ?

• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN

Abrégé

The present invention relates to a pharmaceutical composition for preventing and treating breast cancer, containing an Inula helenium fraction or a compound isolated therefrom as an active ingredient. More specifically, the present invention exhibits selective inhibitory effects on tyrosine phosphorylation activity of STAT3 in breast cancer cells and in a mouse in which breast cancer cells have been transplanted, effectively inhibits the expression of STAT3 target genes, effectively suppresses cancer metastasis, and effectively reduces the weight and volume of a tumor. Therefore, the Inula helenium fraction or the compound isolated therefrom can be effectively used as an active ingredient of a pharmaceutical composition for preventing or treating breast cancer, a composition for suppressing breast cancer metastasis, a functional health food for preventing and alleviating breast cancer, a functional health food for suppressing breast cancer metastasis, or an anticancer adjuvant.

Classes IPC  ?

• A61K 36/28 - Asteraceae ou Compositae (famille de l'aster ou du tournesol), p. ex. camomille, chrysanthème matricaire, achillée ou echinacée
• A61K 31/343 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à cinq chaînons avec un oxygène comme seul hétéro-atome d'un cycle, p. ex. isosorbide condensés avec un carbocycle, p. ex. coumarane, bufaralol, béfunolol, clobenfurol, amiodarone
• A61P 35/00 - Agents anticancéreux

Abrégé

The purpose of the present invention is to provide a strip cast magnesium alloy board, wherein the solidification range of a magnesium alloy is controlled by adding, on the basis of a Mg-Al alloy system, an alloy element such as manganese (Mn), tin (Sn), calcium (Ca) or misch metal (Mm), thereby controlling the segregation fraction generated in a strip casting process, and thus the magnesium alloy board has excellent mechanical properties compared with a conventional magnesium alloy board. A magnesium alloy board for strip casting according to the present invention is a Mg-Al-Mn-X (X= Ca or RE) alloy system comprising Al in an amount of more than 3.0 wt% and less than or equal to 10.0 wt% and 0.1-3.0 wt% of Mn, and comprising 0.1-5.0 wt% of Ca or 0.1-5.0 wt% of a rare earth metal and the balance of magnesium and inevitable impurities, and a Mg-Al-Sn-X (X=Ca or RE) alloy system comprising Al of 3.0-10.0 wt%, 0.1-6.0 wt% of Sn and 0.1-0.3 wt% of Mn, and comprising 0.1-5.0 wt% of Ca or 0.1-5.0 wt% of a rare earth metal and the balance of magnesium and inevitable impurities, and thus the segregation fraction of the board is less than or equal to 2.5%.

Classes IPC  ?

• C22C 23/02 - Alliages à base de magnésium avec l'aluminium comme second constituant majeur
• B22D 21/04 - Coulée d'aluminium ou de magnésium
• B22D 11/06 - Coulée continue des métaux, c.-à-d. en longueur indéfinie dans des moules dont les parois se déplacent, p. ex. entre des rouleaux, des plaques, des courroies, des chenilles

Abrégé

The present invention relates to a method for increasing resistance to non-biological stress of a plant, the method comprising a step of transfecting plant cells with a recombinant vector including an Oryza sativa-derived nuclear factor Y, subunit A7 (NF-YA7) protein coding gene, and the Oryza sativa-derived NF-YA7 protein coding gene of the present invention can be favorably used to develop a transgenic plant with increased resistance to drought stress.

Classes IPC  ?

• C12N 15/29 - Gènes codant pour des protéines végétales, p. ex. thaumatine
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique

Abrégé

Disclosed are a method for mitigating interference in a wireless communication system supporting device-to-device (D2D) communication, and a device for same. A method, for mitigating interference in D2D communication in a wireless communication system supporting D2D communication, can particularly comprise the steps of: a device receiving a D2D signal; the device determining whether or not interference occurs in resources in which the D2D signal has been transmitted; and, if interference is determined to have occurred in the resources in which the D2D signal has been transmitted, the device transmitting interference resource information for indicating that the interference has occurred in the resources in which the D2D signal has been transmitted.

Classes IPC  ?

• H04J 11/00 - Systèmes multiplex orthogonaux

Abrégé

The present invention provides a guide RNA capable of recognizing AAVS1 in canine cells, a composition containing the same, and a method for producing a canine cell line capable of stably expressing a foreign gene using the same. The foreign gene can be stably expressed in the canine cell line by using the present invention. Therefore, the present invention can be favorably used for the studies of diagnostic and therapeutic purposes using genes, and can be further applied to the production of cell lines expressing proteins useful to people.

Classes IPC  ?

• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression

Abrégé

A washing machine includes a tub; a drum rotatably disposed inside the tub; and an ultrasound generator configured to emit ultrasonic waves to washing water loaded in the drum, and to generate bubbles. The ultrasound generator applies ultrasonic energy to the washing water to cause chaotic oscillation of the bubbles.

Classes IPC  ?

• D06F 19/00 - Machines à laver utilisant des vibrations pour le lavage

Abrégé

The present invention relates to a phenoxyacetyl derivative compound and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating nonalcoholic fatty liver disease. The compound according to the present invention is excellent in the inhibition of SREBP-1c activity and FAS expression, and is thus expected to be able to be usefully used as an active ingredient of a pharmaceutical composition or a functional food composition for preventing, ameliorating or treating nonalcoholic fatty liver disease.

Classes IPC  ?

• C07C 235/24 - Amides d'acides carboxyliques, le squelette carboné de la partie acide étant substitué de plus par des atomes d'oxygène ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone acycliques et des atomes d'oxygène, liés par des liaisons simples, liés au même squelette carboné le squelette carboné étant acyclique et saturé ayant au moins l'un des atomes d'oxygène liés par des liaisons simples, lié de plus à un atome de carbone d'un cycle aromatique à six chaînons, p. ex. phénoxyacétamides ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un cycle aromatique à six chaînons
• A61K 31/165 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques

Abrégé

The present invention relates to a pharmaceutical composition containing a G protein coupled receptor 119 (GPR119) ligand as an active ingredient for preventing or treating non-alcoholic fatty liver disease. More specifically, it was established that the GPR119 ligand, which has been developed as only an anti-diabetic medicine, exhibits an excellent effect in the treatment of non-alcoholic fatty liver, and the signaling pathway in liver cells therefor is different from the signaling pathway in the small intestine or pancreas exhibiting an anti-diabetic effect, and thus it was confirmed that the GPR119 ligand can be useful to treat non-alcoholic fatty liver.

Classes IPC  ?

• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 31/4245 - Oxadiazoles
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques

Abrégé

The present invention relates to a movable apparatus for collecting floating matters and, more particularly, to a movable apparatus for collecting floating matters, which is moved on the ground by means of a vehicle, separated from the vehicle in the body of water from which floating matters are to be collected, and mounted on the side of a vessel so that the apparatus can collect floating matters from the surface of water. The present invention provides a movable apparatus for collecting floating matters, comprising: a collection tank; a buoyant body surrounding the collection tank; wheels equipped on the buoyant body; and a vehicle connector for connecting the buoyant body to the vehicle. Accordingly, the present invention is capable of collecting floating matters after quickly moving to a natural water system from which floating matters are to be collected.

Classes IPC  ?

• B63B 35/32 - Embarcations ou structures flottantes similaires spécialement adaptées à des finalités spécifiques et non prévues ailleurs pour le ramassage des matières polluantes au large
• E02B 15/04 - Dispositifs pour éliminer le mazout ou les produits flottants similaires de la surface de l'eau ou pour l'en maintenir exempte, en séparant ou en enlevant ces matériaux

Abrégé

The present invention relates to an electrode catalyst, a method for preparing the same, and a membrane electrode assembly and a fuel cell comprising the same, wherein the electrode catalyst includes a carbon based carrier and a platinum based catalyst carried on the carbon based carrier, and the carbon based carrier is selectively bonded to a thermally reactive polymer. The electrode catalyst can smoothly discharge water generated as a result of electrochemical reaction, and thus improve the electrical performance of the fuel cell.

Classes IPC  ?

• H01M 4/90 - Emploi de matériau catalytique spécifié
• H01M 4/86 - Électrodes inertes ayant une activité catalytique, p. ex. pour piles à combustible
• H01M 8/02 - Éléments à combustibleLeur fabrication Détails

Abrégé

The present invention provides a screening method for a therapeutic agent of GPCR19-related condition. In addition, the present invention provides an efficacy analysis method for a GPCR19 agonist. Also, the present invention provides a myeloid-derived suppressor cell (MDSC) which is formed by being treated with an in vivo physiological activity regulator and a GPCR19 agonist, and has Gr-1+CD11b+ surface phenotype and anti-inflammatory activity. Also, the present invention provides an immunoregulatory B cell which is formed by being treated with an in vivo physiological activity regulator and a GPCR19 agonist, or is formed by the H-MDSC treatment, and has B220+ surface phenotype and anti-inflammatory activity. Also, the present invention provides an anti-inflammatory pharmaceutical composition comprising an H-MDSC or BHM cell as an active ingredient. Also, the present invention provides an anticancer pharmaceutical composition comprising an H-MDSC, 48H BH or BHM cell as an active ingredient. Also, the present invention provides an anti-inflammatory pharmaceutical composition comprising a GPCR19 agonist which is composed for the purpose of in vivo amplifying an H-MDSC or 48H BH cell. According to the present invention, the number of H-MDSCs is increased by administration of sodium taurodeoxycholate (HY-2191) in a mouse in which inflammation is induced by administration of lipopolysaccharide (LPS), and the increased H-MDSCs reveal a marked therapeutic effect on sepsis. According to the present invention, the number of immunoregulatory B cells (48h BH cells) is increased by administration of sodium taurodeoxycholate (HY-2191) in a mouse in which inflammation is induced by administration of lipopolysaccharide (LPS), and the increased 48h BH cells reveal a marked therapeutic effect on sepsis. According to the present invention, the number of BHM cells is increased by administration of H-MDSC in a mouse in which inflammation is induced by administration of lipopolysaccharide (LPS), and the increased BHM cells reveal a marked therapeutic effect on sepsis.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• C12N 5/0781 - Cellules BLeurs progéniteurs

Abrégé

A high-speed frame exchange method that increases the efficiency of a resource and enables reliable transmission is disclosed. A method performed by a terminal includes the steps of: receiving a first downlink data frame including a specific field where a bit value requesting a response using a data frame from an access point is set; and transmitting a second uplink data frame to the access point in response to the first downlink data frame based on the bit value of the specific field. Thus, since it is possible to respond to data frame reception by using another data frame, it is possible to increase the efficiency of a resource.

Classes IPC  ?

• H04B 7/26 - Systèmes de transmission radio, c.-à-d. utilisant un champ de rayonnement pour communication entre plusieurs postes dont au moins un est mobile

Abrégé

The present invention relates to a protein, wherein the hydroxylation and oxidation of a tyrosine moiety of a protein is catalyzed with high efficiency by using actinomycete-derived tyrosinase, and remarkable adhesion, high thermal stability and mechanical stability are provided through the cross-linking of a catechol- or quinone-structured material generated thereby. In addition, it is possible to immobilize an enzyme and prepare a biocompatible material by applying the protein.

Classes IPC  ?

• C12P 21/04 - Peptides ou polypeptides cycliques ou pontés, p. ex. bacitracine
• C12N 11/06 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique attachées au support au moyen d'un agent de pontage
• A61L 24/10 - PolypeptidesProtéines
• A61L 27/22 - Polypeptides ou leurs dérivés

Abrégé

The present invention relates to a biomarker for evaluating or predicting patient's therapeutic response to metformin, and a use thereof. The present invention relates to a composition and kit for evaluating and predicting patient's therapeutic response to metformin, the composition and the kit each containing an agent capable of detecting at least one microorganism selected from the group consisting of Blautia, Shigella, and Clostridium. Further, the present invention relates to a method for detecting at least one microorganism selected from the group consisting of Blautia, Shigella, and Clostridium, from a sample of the patient, in order to provide information necessary for evaluating or predicting the response to metformin.

Classes IPC  ?

• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• G01N 33/48 - Matériau biologique, p. ex. sang, urineHémocytomètres

Abrégé

In the present invention, a copper electrode having a nanohole structure is prepared by using a polymer substrate in the form of nanopillars in order to avoid fatigue fracture that causes degradation of electrical and mechanical properties of a flexible electrode during repetitive bending of a typical metal electrode. The nanohole structure may annihilate dislocations to suppress the initiation of fracture and may blunt crack tips to delay the propagation of damage. Therefore, the nanohole electrode exhibits very small changes in electrical resistance during a bending fatigue test.

Classes IPC  ?

• B05D 5/00 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers
• H05K 1/09 - Emploi de matériaux pour réaliser le parcours métallique
• H05K 3/14 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué au support isolant de manière à former le parcours conducteur recherché utilisant la technique de la vaporisation pour appliquer le matériau conducteur

Abrégé

A method for simulating a circuit according to the present embodiment comprises the steps of: receiving an input of a circuit and stimulation in the form of a basis function; obtaining a transfer function of the circuit and a formula for an s domain related to the stimulation in the form of the basis function; and calculating the transfer function and the formula for the s domain expressing the stimulation, and obtaining a response, which is converted into a formula for a time domain of the circuit, to the stimulation in the form of the basis function.

Classes IPC  ?

• G01R 31/28 - Test de circuits électroniques, p. ex. à l'aide d'un traceur de signaux
• G01R 31/317 - Tests de circuits numériques
• G06F 9/455 - ÉmulationInterprétationSimulation de logiciel, p. ex. virtualisation ou émulation des moteurs d’exécution d’applications ou de systèmes d’exploitation

Abrégé

A method for simulating a circuit according to the present embodiment comprises the steps of: receiving an input of a circuit and stimulation in the form of a basis function; obtaining a transfer function of the circuit and a formula for a complex frequency domain related to the stimulation in the form of the basis function; and calculating the transfer function and the formula for the complex frequency domain expressing the stimulation, and obtaining a response, which is converted into a formula for a time domain of the circuit, to the stimulation in the form of the basis function.

Classes IPC  ?

• G01R 31/28 - Test de circuits électroniques, p. ex. à l'aide d'un traceur de signaux
• G01R 31/317 - Tests de circuits numériques
• G06F 9/455 - ÉmulationInterprétationSimulation de logiciel, p. ex. virtualisation ou émulation des moteurs d’exécution d’applications ou de systèmes d’exploitation

Abrégé

The present invention relates to a modularized patient-specific registration guide and a system using the same and, more specifically, to a modularized patient-specific registration guide capable of rapidly carrying out an initial registration step for a bone, which is a surgical site, and inducing a registration step to be easily performed even during an operation, and a system using the same. The modularized patient-specific registration guide, according to one embodiment of the present invention, is a registration guide manufactured according to a three-dimensional shape of a bone obtained in an imaging device, the registration guide comprising: a first member having one or more markers and one or more extending parts that come in contact with the bone, and having a groove on one side thereof; and a second member accommodated in or separable from the groove of the first member and having one or more markers.

Classes IPC  ?

• A61B 17/90 - Dispositifs de guidage à cet effet
• A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
• A61F 2/46 - Outils particuliers pour l'implantation des articulations artificielles

Abrégé

The present invention relates to: a method for inducing tailored pluripotent stem cells by reprogramming differentiated cells of an adult by using an extract of plant stem cells and plant dedifferentiated stem cells (callus); pluripotent stem cells produced by means of the method; and a cell therapy agent comprising the pluripotent stem cells. According to the present invention, it is possible to overcome ethical problems since eggs are not used in the making of pluripotent stem cells having abilities like embryonic stem cells, and it is possible to produce pluripotent stem cells of ensured safety because use is made of a plant stem cell extract which above all has been verified to be harmless to the body, and it is also possible to use the invention to develop an immunocompatible cell therapy agent tailored to different individuals. In addition, the invention can be expected to be used to great advantage in elucidating the causes and studying methods of treating medical conditions by inducing pluripotent stem cells from individuals having diseases.

Classes IPC  ?

• C12N 5/04 - Cellules ou tissus végétaux
• A61K 8/97 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base d’algues, de champignons, de lichens ou de plantesCosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés à base de leurs dérivés

Abrégé

The present invention relates to a method for manufacturing water-dispersible silica nanoparticles. More specifically, the present invention relates to a method for manufacturing silica nanoparticles, which includes a step of carrying out a reaction by adding an alkaline substance and a silica precursor to a solution obtained by dissolving polyvinyl pyrrolidone in a mixed solution of C1-C4 alcohol and water.

Classes IPC  ?

• C01B 33/12 - SiliceSes hydrates, p. ex. acide silicique lépidoïque
• C08F 26/10 - N-Vinylpyrrolidone
• C08J 3/12 - Pulvérisation ou granulation
• B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles

Abrégé

The present invention relates to a method and a system for wirelessly transmitting electric power, and a computer-readable recording medium. According to an aspect of the present invention, provided is a system for wirelessly transmitting electric power, the system including a transmission antenna, a reception antenna spaced apart from the transmission antenna by a changing distance, and a source consisting of a D type power amplifier for supplying electric power to the transmission antenna. According to the present invention, even in an environment in which an operation frequency of a wireless power transmission system is fixed and the distance between the transmission antenna and the reception antenna changes, a high power transmission efficiency can be maintained only through a simple control of the D type power amplifier or load impedance.

Classes IPC  ?

• H02J 17/00 - Systèmes pour l'alimentation ou la distribution d'énergie par ondes électromagnétiques

Abrégé

The present invention relates to a method for producing a collagen scaffold coated with apatite by processing a surface of the collagen scaffold with a simulated body fluid of pH 8-13. The collagen scaffold coated by apatite, according to the present invention, is effectively produced in a short period of time and is modified so as to have osteanagenesis effects including excellent biocompatibility, cell compatibility, osteoconductive properties, and osteogenic protein sustained-release properties, and is thus useful as a medical graft material.

Classes IPC  ?

• A61L 27/56 - Matériaux poreux ou cellulaires
• A61L 27/24 - Collagène
• A61F 2/28 - Os

Abrégé

The present invention relates to a method of a terminal subscribing to a network via a router or an end device in a wireless network (WN) of a tree structure comprising routers and end devices. According to the present invention, each router receives, from the parent router thereof, addresses which can be used independently for child routers or child end devices thereof, and divides the addresses into general addresses and special addresses. The present invention allows a terminal wishing to subscribe to a network to subscribe to the network by using a special address of the end device, only when the terminal cannot subscribe to the network by using a general address of the end device, thereby minimizing address depletion to be used for subscription of terminals and facilitating the end devices to subscribe a network. Additionally, if a router determines that end devices of peripheral devices have finished subscription to a network, the router selects as many child end devices having a low received signal strength (RSS) (i.e., easy to extend a network remotely) as the number of general addresses available for child routers and then converts the child end devices to child routers, thereby providing network extensibility by an increase in network depth and minimizing the use of the special addresses by the router. Furthermore, if a terminal wishing to subscribe to a network via an end device fails to subscribe to the network, or a terminal which has subscribed to a network via a router wishes to re-subscribe to the network, the present invention facilitates such a terminal to re-subscribe to the network by allowing the terminal to subscribe to the network using a special address for the router. Compared to conventional techniques, the present invention can significantly enhance the success rate of subscription to a large-scale WN through the two-step address allocation and the selection of the child routers.

Classes IPC  ?

• H04L 12/753 - Découverte de l’arborescence de routage, p.ex. conversion de la topologie maillée de réseau en topologie arborescente

Abrégé

The present invention provides an organic light-emitting diode comprising a light-emitting layer which contains a dopant having improved horizontal orientation properties and employs a host/dopant system. One embodiment of the organic light-emitting diode according to one aspect of the present invention comprises: an anode layer; a light-emitting layer which is disposed on the anode layer and comprises a host comprising a hole transport material and an electron transport material, which form an exciplex, and a dopant comprising an Ir(mphmq)2tmd-based phosphor; and a cathode layer disposed on the light-emitting layer.

Classes IPC  ?

• H01L 51/50 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés pour l'émission de lumière, p.ex. diodes émettrices de lumière organiques (OLED) ou dispositifs émetteurs de lumière à base de polymères (PLED)