Comprehensive and Integrative Medicine Institute

République de Corée

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Classe IPC
A61K 36/232 - Angelica 5
A61K 36/076 - Poria 3
A61K 36/484 - Glycyrrhiza (réglisse) 3
A61K 36/65 - Paeoniaceae (famille de la pivoine), p. ex. pivoine chinoise 3
A61K 36/804 - Rehmannia 3
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1.

Composition for treating diabetes, containing extract of yukmijihwangtang

      
Numéro d'application 15970282
Numéro de brevet 10765647
Statut Délivré - en vigueur
Date de dépôt 2018-05-03
Date de la première publication 2019-02-14
Date d'octroi 2020-09-08
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Kang, Seok Bong
  • Sohn, Ho Sang
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

Provided is a composition for treating diabetes, including a hypoglycemic agent and a Yukmijihwang-tang extract. More particularly, the hypoglycemic agent is administered into an individual, and the Yukmijihwang-tang extract is administered into the individual, thereby considerably increasing a hypoglycemic effect of the hypoglycemic agent, and preventing and reducing various diabetic complications such as diabetes and diabetic liver damage, renal damage, hyperlipidemia immunosuppression and ocular damage.

Classes IPC  ?

  • A61K 31/155 - Amidines (), p. ex. guanidine (H2N-C(=NH)-NH2), isourée (HN=C(OH)NH2), isothiourée (HN=C(SH)-NH2)
  • A61K 36/884 - Alismataceae (famille du fluteau)
  • A61K 36/8945 - Dioscorea, p. ex. igname, Dioscorea opposita ou Dioscorea alata
  • A61K 36/40 - Cornaceae (famille du cornouiller)
  • A61K 36/65 - Paeoniaceae (famille de la pivoine), p. ex. pivoine chinoise
  • A61K 36/804 - Rehmannia
  • A61K 36/076 - Poria
  • A61K 36/53 - Lamiaceae ou Labiatae (famille de la menthe), p. ex. thym, romarin ou lavande

2.

Composition containing herbal medicine extracts of Pinellia and Scutellaria for reducing side effects due to anticancer drugs

      
Numéro d'application 15963424
Numéro de brevet 10695394
Statut Délivré - en vigueur
Date de dépôt 2018-04-26
Date de la première publication 2018-10-11
Date d'octroi 2020-06-30
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Ryu, Heon Mo
  • Kim, Dae Jun
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition containing a Pinelliae Rhizoma and Scutellariae Radix extract as an active ingredient to reduce side effects caused by an anticancer drug, and more particularly, a composition for reducing side effects such as damage to the gastrointestinal tract and a gastrointestinal motility disorder by administering an anticancer drug. The composition of the present invention has an excellent effect of reducing side effects in administration of the anticancer drug through an antioxidative function, and synthesis, secretion and control of the functions of gastrin and serotonin producing gastrointestinal endocrine cells.

Classes IPC  ?

  • A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
  • A61K 36/8888 - Pinellia
  • A61K 36/539 - Scutellaria (calotte)

3.

Composition containing angelica extract for promoting proliferation of stem cells derived from bone marrow

      
Numéro d'application 15969762
Numéro de brevet 10342835
Statut Délivré - en vigueur
Date de dépôt 2018-05-02
Date de la première publication 2018-08-30
Date d'octroi 2019-07-09
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Lee, Chang Hyeong
  • Kim, Sang Gyung
  • Shin, Im Hee
  • Kim, Seung Mo
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition for promoting proliferation of bone marrow derived stem cells using an angelicae gigantis radix extract, and more particularly, to a composition which administers a granulocyte colony-stimulating factor into an object, and administers the angelicae gigantis radix extract to the object to promote the proliferation of the bone marrow derived stem cells. The composition of the present invention solves side effects such as splenomegaly which were caused by a method of administering only the G-CSF for proliferation and differentiation of the stem cells, thereby significantly mitigating the side effects through co-administration of the angelicae gigantis radix extract, and further promoting the proliferation and the differentiation of the stem cells.

Classes IPC  ?

4.

Composition containing palmultang extract for promoting proliferation of stem cells derived from bone marrow

      
Numéro d'application 15854613
Numéro de brevet 10286040
Statut Délivré - en vigueur
Date de dépôt 2017-12-26
Date de la première publication 2018-07-05
Date d'octroi 2019-05-14
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Lee, Chang Hyeong
  • Kim, Sang Gyung
  • Shin, Im Hee
  • Kim, Seung Mo
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmultang extract, and more specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering the palmultang extract to the subject. The composition of the present invention remarkably reduces side effects, such as enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, through administration in combination with the palmultang extract, thereby further promoting the proliferation and differentiation of stem cells.

Classes IPC  ?

5.

Composition including oriental medicine to treat neoplastic disease

      
Numéro d'application 14891284
Numéro de brevet 11065294
Statut Délivré - en vigueur
Date de dépôt 2014-05-15
Date de la première publication 2016-06-30
Date d'octroi 2021-07-20
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Byun, Joon Seok
  • Ku, Sae Kwang
  • Sohn, Ki Cheul
  • Kim, Seung Mo
  • Lee, Chang Hyeong
  • Hyun, Dae Sung
  • Kim, Jong Dae
  • Park, Sung Hwan
  • Kwak, Min A.

Abrégé

Provided is a composition for enhancing effects of an anticancer agent using an oriental medicine, jaeumganghwa-tang, bojungikgi-tang, or yukmijihwang-tang. More particularly, provided is a composition for treating a neoplastic disease by administering an anticancer agent into an individual, and administering an oriental medicine into the individual within 30 minutes. The composition remarkably reduces side effects occurring when the anticancer agent is administered alone by co-administration of the oriental medicine, reduces cytotoxicity, and has higher anticancer activity than that when the anticancer agent is administered alone.

Classes IPC  ?

  • A61K 36/9068 - Zingiber, p. ex. gingembre
  • A61K 31/138 - Aryloxyalkylamines, p. ex. propranolol, tamoxifène, phénoxybenzamine
  • A61K 36/232 - Angelica
  • A61K 36/484 - Glycyrrhiza (réglisse)
  • A61K 36/725 - Ziziphus, p. ex. jujube
  • A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
  • A61K 31/44 - Pyridines non condenséesLeurs dérivés hydrogénés
  • A61K 31/4412 - Pyridines non condenséesLeurs dérivés hydrogénés ayant des groupes oxo liés directement à l'hétérocycle
  • A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
  • A61K 36/28 - Asteraceae ou Compositae (famille de l'aster ou du tournesol), p. ex. camomille, chrysanthème matricaire, achillée ou echinacée
  • A61K 36/53 - Lamiaceae ou Labiatae (famille de la menthe), p. ex. thym, romarin ou lavande
  • A61K 36/65 - Paeoniaceae (famille de la pivoine), p. ex. pivoine chinoise
  • A61K 36/752 - Citrus, p. ex. citron vert, orange ou citron
  • A61K 36/756 - Phellodendron, p. ex. chêne-liège
  • A61K 36/88 - Liliopsida (monocotylédones)

6.

COMPOSITION CONTAINING HERBAL MEDICINE EXTRACTS OF PINELLIA AND SCUTELLARIA FOR REDUCING SIDE EFFECTS DUE TO ANTICANCER DRUGS

      
Numéro d'application KR2014004548
Numéro de publication 2014/193114
Statut Délivré - en vigueur
Date de dépôt 2014-05-21
Date de publication 2014-12-04
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Ryu, Heon Mo
  • Kim, Dae Jun
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition containing herbal medicine extracts of Pinellia and Scutellaria, as active ingredients, for reducing side effects due to anticancer drugs, and more specifically, to a composition for reducing side effects, the composition having an effect of reducing side effects, such as gastrointestinal damage and gastrointestinal dyskinesia, caused by administering anticancer drugs. The composition of the present invention has an excellent effect of reducing side effects at the time of administering anticancer drugs, through an antioxidative function, gastrin and serotonin production, and synthesis, secretion, and functional regulation of gastrointestinal endocrine cells.

Classes IPC  ?

7.

COMPOSITION FOR TREATING NEOPLASTIC DISEASES, CONTAINING MEDICINAL HERB PRODUCTS

      
Numéro d'application KR2014004375
Numéro de publication 2014/185733
Statut Délivré - en vigueur
Date de dépôt 2014-05-15
Date de publication 2014-11-20
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Byun, Joon Seok
  • Ku, Sae Kwang
  • Sohn, Ki Cheul
  • Kim, Seung Mo
  • Lee, Chang Hyeong
  • Hyun, Dae Sung
  • Kim, Jong Dae
  • Park, Sung Hwan
  • Kwak, Min A

Abrégé

The present invention relates to a composition for increasing the effect of an anticancer drug using Jaeumganghwatang, Bojungikgitang or Yukmijihwangtang, which are medicinal herb products, and more specifically, to a composition for treating neoplastic diseases by administering an anticancer drug to an individual, and then administering a medicinal herb product to the individual within 30 minutes. The composition of the present invention remarkably alleviates side effects during a single administration of an anticancer drug by using concomitant administration of a medicinal herb product, has low cytotoxicity, and shows higher anticancer activity compared to the single administration of an anticancer drug.

Classes IPC  ?

8.

COMPOSITION FOR TREATING DIABETES, CONTAINING EXTRACT OF YUKMIJIHWANGTANG

      
Numéro d'application KR2014003978
Numéro de publication 2014/182028
Statut Délivré - en vigueur
Date de dépôt 2014-05-02
Date de publication 2014-11-13
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Kang, Seok Bong
  • Sohn, Ho Sang
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition for treating diabetes, containing a hypoglycemic agent and an extract of Yukmijihwangtang (a soup of six different medicinal herbs). More specifically, the composition remarkably improves a hypoglycemic effect of a hypoglycemic agent by administering the hypoglycemic agent to an individual and administering an extract of Yukmijihwangtang to the individual, and prevents and alleviates diabetes and various diabetic complications such as diabetic liver damage, kidney damage, hyperlipidemia, immunosuppression, eye damage and the like.

Classes IPC  ?

  • A61K 31/155 - Amidines (), p. ex. guanidine (H2N-C(=NH)-NH2), isourée (HN=C(OH)NH2), isothiourée (HN=C(SH)-NH2)
  • A61K 36/804 - Rehmannia
  • A61K 36/076 - Poria
  • A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques

9.

COMPOSITION CONTAINING PALMUL-TANG EXTRACT FOR PROMOTING PROLIFERATION OF STEM CELLS DERIVED FROM BONE MARROW

      
Numéro d'application KR2014003909
Numéro de publication 2014/178675
Statut Délivré - en vigueur
Date de dépôt 2014-05-01
Date de publication 2014-11-06
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Lee, Chang Hyeong
  • Kim, Sang Gyung
  • Shin, Im Hee
  • Kim, Seung Mo
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using a palmul-tang extract, and more specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering a palmul-tang extract to the subject. The composition of the present invention remarkably reduces side effects, such as the enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, by being administration in combination with the palmul-tang extract, thereby further promoting the proliferation and differentiation of the stem cells.

Classes IPC  ?

  • C12N 5/02 - Propagation de cellules individuelles ou de cellules en suspensionLeur conservationMilieux de culture à cet effet
  • C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires

10.

COMPOSITION CONTAINING ANGELICA EXTRACT FOR PROMOTING PROLIFERATION OF STEM CELLS DERIVED FROM BONE MARROW

      
Numéro d'application KR2014003910
Numéro de publication 2014/178676
Statut Délivré - en vigueur
Date de dépôt 2014-05-01
Date de publication 2014-11-06
Propriétaire COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE (République de Corée)
Inventeur(s)
  • Lee, Chang Hyeong
  • Kim, Sang Gyung
  • Shin, Im Hee
  • Kim, Seung Mo
  • Byun, Joon Seok
  • Sohn, Ki Cheul
  • Ku, Sae Kwang

Abrégé

The present invention relates to a composition for promoting the proliferation of stem cells derived from bone marrow using an Angelica extract, and more specifically, to a composition for promoting the proliferation of stem cells derived from bone marrow by administering a granulocyte colony-stimulating factor to a subject and then administering an Angelica extract to the subject. The composition of the present invention remarkably reduces side effects, such as the enlargement of the spleen, which are caused by the administration of G-CSF alone for proliferation and differentiation of the stem cells, by being administration in combination with the Angelica extract, thereby further promoting the proliferation and differentiation of the stem cells.

Classes IPC  ?