Abrégé

The present disclosure relates generally to the manufacturing of gene therapy products and specifically to viral vector formulations comprising a high-density additive for increasing transduction of a cell with a viral vector and/or methods of transducing a cell with a viral vector in a cell culture and/or methods of increasing a viral vector transduction efficiency of a cell in a cell culture, the methods comprising using a viral vector formulation comprising a high-density additive, wherein the formulation has a density greater than the density of the cell culture medium.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• C12N 15/79 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes
• A61K 35/76 - VirusParticules sous-viralesBactériophages
• A61K 39/12 - Antigènes viraux
• A61K 35/66 - Micro-organismes ou substances provenant de micro-organismes

Produits et services

Pharmaceutical preparations for treating von Willebrand disease, hemophilia, primary immunodeficiency, hereditary angioedema, fibrinogen deficiency, Alpha 1antitrypsin deficiency, and inflammatory demyelinating polyneuropathy; blood plasma; blood plasma fractions; recombinant protein arrays for medical diagnosis purposes; Pharmaceutical preparations for the treatment and prevention of blood and bleeding disorders; blood products for the treatment of hemophilia, namely, pharmaceutical preparations for the treatment of hemophilia; pharmaceutical products derived from recombinant DNA technology for the treatment of hemophilia, namely, pharmaceutical preparations derived from recombinant DNA technology for the treatment of hemophilia; blood products for the treatment of hemophilia, namely, a blood clotting aid and delivery system for use in human and veterinary medicine; pharmaceutical preparations and substances for the treatment of blood disorders; antibodies, namely, diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; blood for medical purposes; cell cultures for medical purposes, namely, cells for medical or clinical use; cell cultures for medical purposes, namely, living cells for medical use; cell cultures for medical purposes, namely, stem cells for medical or veterinary use; pharmaceutical preparations for the treatment of blood conditions, respiratory conditions, pneumonia, covid-19, and influenza; Pharmaceutical preparations, namely, antibody for the treatment of acute respiratory distress syndrome, ARDS; pharmaceutical preparations, namely, antibody for the treatment of Idiopathic Pulmonary Fibrosis, IPF and Interstitial Lung Diseases, ILD; Pharmaceutical preparations, namely, antibody for the treatment of Hereditary Angioedema, HAE

Produits et services

Pharmaceutical preparations for treating von Willebrand disease, hemophilia, primary immunodeficiency, hereditary angioedema, fibrinogen deficiency, Alpha 1 antitrypsin deficiency, and inflammatory demyelinating polyneuropathy; blood plasma; blood plasma fractions; recombinant protein arrays for medical diagnosis purposes; Pharmaceutical preparations for the treatment and prevention of blood and bleeding disorders; blood products for the treatment of hemophilia, namely, pharmaceutical preparations for the treatment of hemophilia; pharmaceutical products derived from recombinant DNA technology for the treatment of hemophilia, namely, pharmaceutical preparations derived from recombinant DNA technology for the treatment of hemophilia; blood products for the treatment of hemophilia, namely, a blood clotting aid and delivery system for use in human and veterinary medicine; pharmaceutical preparations and substances for the treatment of blood disorders; antibodies, namely, diagnostic kits consisting primarily of monoclonal antibodies, buffers, and reagents for use in disease testing; blood for medical purposes; cell cultures for medical purposes, namely, cells for medical or clinical use; cell cultures for medical purposes, namely, living cells for medical use; cell cultures for medical purposes, namely, stem cells for medical or veterinary use; pharmaceutical preparations for the treatment of blood conditions, respiratory conditions, pneumonia, covid-19, and influenza; Pharmaceutical preparations, namely, antibody for the treatment of acute respiratory distress syndrome, ARDS; pharmaceutical preparations, namely, antibody for the treatment of Idiopathic Pulmonary Fibrosis, IPF and Interstitial Lung Diseases, ILD; Pharmaceutical preparations, namely, antibody for the treatment of Hereditary Angioedema, HAE

Abrégé

The present disclosure relates generally to the manufacturing of gene therapy products, and specifically to methods of purifying an enveloped virus from a cell culture fluid, comprising a filtration medium.

Classes IPC  ?

• C12N 7/02 - Isolement ou purification
• B01D 15/34 - Séparation par sélection en fonction de la taille, p. ex. chromatographie d'exclusion de tailleFiltration sur gelPerméation
• B01D 37/00 - Procédés de filtration
• B01D 39/16 - Autres substances filtrantes autoportantes en substance organique, p. ex. fibres synthétiques
• B01D 63/14 - Modules à membranes du type plissé
• B01D 69/12 - Membranes compositesMembranes ultraminces

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Abrégé

The present disclosure relates generally to the manufacturing of gene therapy products, and specifically to methods of transducing a cell with an enveloped virus in a cell culture, methods of increasing an enveloped virus transduction efficiency of a cell in a cell culture and/or methods of increasing potency of an enveloped virus during transduction of a cell in a cell culture, the method contacting a plurality of cells in a cell culture medium with the enveloped virus and a transduction enhancer of Formula (I) or a stereoisomer, a racemate, a pharmaceutically acceptable salt or a solvate thereof.

Classes IPC  ?

• C12N 5/074 - Cellules souches adultes
• C07D 407/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C12N 15/86 - Vecteurs viraux

Produits et services

Human albumin [pharmaceutical preparations] for use in human therapy.

Abrégé

The present disclosure relates to Wiskott-Aldrich Syndrome (WAS) binding proteins and uses thereof. The present disclosure further relates to WAS protein variants thereof and methods of producing WAS binding proteins thereof.

Classes IPC  ?

• C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
• C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 40/33 - AnticorpsActivateurs de lymphocytes T

Abrégé

The present disclosure relates to methods of producing an enveloped virus in a suspension cell culture, the method comprising culturing a suspension cell line expressing a tetracycline-suppressible gene expression system in a cell culture medium. The present disclosure also relates to stable producer cell clones capable of producing an enveloped virus in a suspension cell culture.

Classes IPC  ?

• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification
• C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p. ex. par magnétisme, par des ondes sonores
• C12N 15/86 - Vecteurs viraux

Abrégé

This disclosure relates generally to lentiviral vectors useful for the treatment of a disease or condition, for example, Wiskott-Aldrich Syndrome (WAS) or Sickle Cell Disease (SCD).

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• A61P 7/00 - Médicaments pour le traitement des troubles du sang ou du fluide extracellulaire
• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères

Produits et services

Human albumin [pharmaceutical preparations] for use in human therapy.

Produits et services

Providing healthcare education services in the field of education regarding healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing healthcare education services in the field of education regarding healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals; Educational services, namely, providing educational speakers in the field of healthcare; Peer to peer healthcare provider coaching services in the field of healthcare; Medical training and teaching in the field of healthcare; Training services in the field of healthcare; Providing on-line training in the field of healthcare; Providing on-line training in the field of healthcare on a peer to peer basis; Training in the use of healthcare products and pharmaceuticals. Providing educational information about healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing educational information about healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals.

Produits et services

Information on financial administration of patient reimbursement programs; Insurance information and consultancy; charitable services, namely, providing financial support and financial information to patients and caregivers for obtaining medications and medical treatment; Providing insurance information for patients diagnosed with medical conditions regarding medication access and reimbursement programs and insurance premium and co-pay assistance; providing insurance consulting services to patients diagnosed with medical conditions regarding obtaining approval, authorization, and verification of insurance coverage for treatment, determining existing insurance benefits, and appealing from denial of insurance coverage and acquiring letters of medical necessity for insurance coverage; providing financial co-pay assistance programs to patients Training services in the field of medical injection training and pharmaceutical administration training health care, namely, providing health care information by telephone, the internet, and through the distribution of printed matter; charitable services, namely, providing medical information to patients and caregivers for obtaining medications and medical treatment; Providing medical information for patients diagnosed with medical conditions regarding available resources and treatments and steps and actions for wellness, and healthy living; providing medical counseling, mentoring and guidance for patients with medical conditions; medical services, namely, providing medical information through charitable actions in the nature of information for the continuance of medication for those who are underinsured, uninsured, or who have experienced a lapse in insurance coverage; Medical services, namely, providing medical information concerning blood products, concerning pharmaceutical products, including providing information on preparing and self-administering medications Providing personal support services for patients and families of patients, namely, emotional counseling and emotional support.

Produits et services

Information on financial administration of patient reimbursement programs; Insurance information and consultancy; charitable services, namely, providing financial support and financial information to patients and caregivers for obtaining medications and medical treatment; Providing insurance information for patients diagnosed with medical conditions regarding medication access and reimbursement programs and insurance premium and co-pay assistance; providing insurance consulting services to patients diagnosed with medical conditions regarding obtaining approval, authorization, and verification of insurance coverage for treatment, determining existing insurance benefits, and appealing from denial of insurance coverage and acquiring letters of medical necessity for insurance coverage; providing financial co-pay assistance programs to patients. Training services in the field of medical injection training and pharmaceutical administration training health care, namely, providing health care information by telephone, the internet, and through the distribution of printed matter; charitable services, namely, providing medical information to patients and caregivers for obtaining medications and medical treatment; Providing medical information for patients diagnosed with medical conditions regarding available resources and treatments and steps and actions for wellness, and healthy living; providing medical counseling, mentoring and guidance for patients with medical conditions; medical services, namely, providing medical information through charitable actions in the nature of information for the continuance of medication for those who are underinsured, uninsured, or who have experienced a lapse in insurance coverage.; Medical services, namely, providing medical information concerning blood products and concerning pharmaceutical products, including providing information on preparing and self-administering medications Providing personal support services for patients and families of patients, namely, emotional counseling and emotional support.

Abrégé

The present disclosure relates to landing pads, proviruses and methods of use thereof.

Classes IPC  ?

• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN

Abrégé

This disclosure relates to an anti-IL-6 antibody (e.g., clazakizumab) and methods for treating end-stage kidney disease (ESKD) with an antibody to interleukin-6 (IL-6). In some embodiments, the anti-IL6 antibody described herein may be used to treat a subject in need thereof, e.g., a human subject diagnosed with ESKD, and/or reduce risks of co-morbidities of ESKD such as cardiovascular death and myocardial infarction.

Classes IPC  ?

• C07K 16/24 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des cytokines, des lymphokines ou des interférons
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins

Produits et services

Providing personal support services for patients and families of patients, namely, emotional counseling and emotional support

Abrégé

The present disclosure relates generally to the manufacturing of gene therapy products, and specifically to methods of producing an enveloped virus in a suspension perfusion cell culture comprising filtering the cell culture fluid through a filter at a harvest rate of at least 2 vessel volumes per day (VVD) to produce a filtered cell culture 5 fluid comprising the enveloped virus, wherein the filter retains cells from the suspension cell line.

Classes IPC  ?

• B01D 15/36 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction ionique, p. ex. échange d'ions, paire d'ions, suppression d'ions ou exclusion d'ions
• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification

Abrégé

The present disclosure generally relates to the manufacturing of gene therapy products, and specifically to methods of producing an enveloped virus from a stable producer cell clone or a stable producer cell pool overexpressing vesicular stomatitis virus G (VSV-G) in suspension cell culture.

Classes IPC  ?

• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• C07K 14/145 - Rhabdoviridae, p. ex. virus de la rage, virus Duvenhage, virus Mokola ou virus de la stomatite vésiculaire
• C12N 15/86 - Vecteurs viraux

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Educational services in the healthcare sector; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Abrégé

The present disclosure relates to a method for reducing or hindering development of renal ischemia-reperfusion injury in a subject the method comprising administering an antibody that inhibits granulocyte colony stimulating factor (G-CSF) signaling. In some examples, the ischemia-reperfusion injury is due to or associated with tissue or organ transplantation.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
• A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins

Abrégé

This disclosure relates generally to vectors, typically viral vectors, useful for the treatment of X-linked agammaglobulinemia (XLA).

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique

Abrégé

Provided is a process including: obtaining, with a computer system hosting a data exchange, a plurality of data sets from a plurality of different users of the data exchange; receiving, with the computer system, a query to search among the plurality of data sets, the query specifying a token; determining a group of data sets among the plurality of data sets that is responsive to the query, wherein determining the group of data sets comprises checking titles, tables, field names, and cell values of data sets among the plurality of data sets for use of the token; determining a ranking of members of the group of data sets responsive to the query; and sending in response to the query, summaries of at least some members of the group of data sets with instructions to present the summaries according to the ranking.

Classes IPC  ?

• G06F 16/34 - NavigationVisualisation à cet effet
• G06F 16/35 - PartitionnementClassement
• G06F 16/24 - Requêtes

Abrégé

Provided is a process including: obtaining, with a computer system hosting a data exchange, a plurality of data sets; receiving from a first user, a selection of a first data set among the plurality of data sets; receiving a message from the first user to be shared with a second user regarding collaboration between the first user and the second user; pre-computing summary statistics or visualizations for each of a plurality of fields of the first data set; causing the message and the summary statistics or visualizations to be presented to the second user in association with the first data set; obtaining another version of the first data set that has undergone revision and logging transformations to the first data set and comments; and causing a listing of versions of the first data set and at least some of the logged changes to be presented.

Classes IPC  ?

• H04L 51/216 - Gestion de l'historique des conversations, p. ex. regroupement de messages dans des sessions ou des fils de conversation
• G06F 40/284 - Analyse lexicale, p. ex. segmentation en unités ou cooccurrence
• G06F 40/44 - Méthodes statistiques, p. ex. modèles probabilistes
• G06F 40/49 - Traduction appuyée sur des données utilisant de très grands corpus, p. ex. le Web
• H04L 51/02 - Messagerie d'utilisateur à utilisateur dans des réseaux à commutation de paquets, transmise selon des protocoles de stockage et de retransmission ou en temps réel, p. ex. courriel en utilisant des réactions automatiques ou la délégation par l’utilisateur, p. ex. des réponses automatiques ou des messages générés par un agent conversationnel
• H04L 51/234 - Surveillance ou traitement des messages pour le suivi des messages
• H04L 51/52 - Messagerie d'utilisateur à utilisateur dans des réseaux à commutation de paquets, transmise selon des protocoles de stockage et de retransmission ou en temps réel, p. ex. courriel pour la prise en charge des services des réseaux sociaux
• G06F 16/21 - Conception, administration ou maintenance des bases de données
• G06F 16/248 - Présentation des résultats de requêtes
• G06F 16/26 - Exploration de données visuellesNavigation dans des données structurées
• G06F 16/9536 - Personnalisation de la recherche basée sur le filtrage social ou collaboratif
• G06F 16/9538 - Présentation des résultats des requêtes
• G06Q 10/063 - Recherche, analyse ou gestion opérationnelles
• G06Q 50/00 - Technologies de l’information et de la communication [TIC] spécialement adaptées à la mise en œuvre des procédés d’affaires d’un secteur particulier d’activité économique, p. ex. aux services d’utilité publique ou au tourisme

Produits et services

Training services in the field of medical infusion therapy

Produits et services

Providing personal support services for patients and families of patients, namely, emotional counseling and emotional support

Produits et services

Providing personal support services for patients and families of patients, namely, emotional counseling and emotional support

Produits et services

Providing healthcare education services in the field of education regarding healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing healthcare education services in the field of education regarding healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals; Educational services, namely, providing educational speakers in the field of healthcare; Peer to peer healthcare provider coaching services in the field of healthcare; Medical training and teaching in the field of healthcare; Training services in the field of healthcare; Providing on-line training in the field of healthcare; Providing on-line training in the field of healthcare on a peer to peer basis; Training in the use of healthcare products and pharmaceuticals. Providing educational information about healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing educational information about healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals.

Produits et services

Providing healthcare education services in the field of education regarding healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing healthcare education services in the field of education regarding healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals; Educational services, namely, providing educational speakers in the field of healthcare; Peer to peer healthcare provider coaching services in the field of healthcare; Medical training and teaching in the field of healthcare; Training services in the field of healthcare; Providing on-line training in the field of healthcare; Providing on-line training in the field of healthcare on a peer to peer basis; Training in the use of healthcare products and pharmaceuticals Providing educational information about healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing educational information about healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals

Produits et services

Providing healthcare education services in the field of education regarding healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing healthcare education services in the field of education regarding healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals; Educational services, namely, providing educational speakers in the field of healthcare; Peer to peer healthcare provider coaching services in the field of healthcare; Medical training and teaching in the field of healthcare; Training services in the field of healthcare; Providing on-line training in the field of healthcare; Providing on-line training in the field of healthcare on a peer to peer basis; Training in the use of healthcare products and pharmaceuticals Providing educational information about healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing educational information about healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals

Produits et services

Providing healthcare education services in the field of education regarding healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing healthcare education services in the field of education regarding healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals; Educational services, namely, providing educational speakers in the field of healthcare; Peer to peer healthcare provider coaching services in the field of healthcare; Medical training and teaching in the field of healthcare; Training services in the field of healthcare; Providing on-line training in the field of healthcare; Providing on-line training in the field of healthcare on a peer to peer basis; Training in the use of healthcare products and pharmaceuticals Providing educational information about healthcare, namely, conducting educational programs for patients, caregivers and healthcare professionals concerning medical diseases, illness or conditions, its treatment and its impact on patients, patient families, caregivers and healthcare professionals; providing educational information about healthcare, namely, planning and conducting educational meetings related to medical diseases, illnesses and conditions, their treatment and their impact on patients, patient families, caregivers and healthcare professionals

Produits et services

Educational services in the field of health; Publication of the results of clinical trials; Educational services relating to therapeutic treatments Providing medical and scientific research information in the field of pharmaceuticals and clinical trials Provision of pharmaceutical information; Provision of medical information

Produits et services

Electronic downloadable publications, namely, booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals in the field of science and medicine; Downloadable software in the nature of a mobile application for healthcare messaging to patients and healthcare providers; Downloadable electronic publications in the nature of booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals, patients and caregivers in the field of medicine Printed publications, namely, booklets, manuals, brochures, letters, informational flyers in the field of medicine; Printed educational publications, namely, booklets, manuals, brochures, letters, informational flyers in the fields of medicine and healthcare; Printed instructional, educational, and teaching materials in the field of medicine; Printed instructional, educational, and teaching materials in the field of medicine for use by medical professionals, patients and caregivers

Produits et services

Information on financial administration of patient reimbursement programs; Insurance information and consultancy; charitable services, namely, providing financial support and financial information to patients and caregivers for obtaining medications and medical treatment; Providing insurance information for patients diagnosed with medical conditions regarding medication access and reimbursement programs and insurance premium and co-pay assistance; providing insurance consulting services to patients diagnosed with medical conditions regarding obtaining approval, authorization, and verification of insurance coverage for treatment, determining existing insurance benefits, and appealing from denial of insurance coverage and acquiring letters of medical necessity for insurance coverage; providing financial co-pay assistance programs to patients. Medical services, namely, providing medical information concerning blood products, providing medical information concerning pharmaceutical products, including providing information on preparing and self-administering medications; health care, namely, providing health care information by telephone, the internet, and through the distribution of printed matter; charitable services, namely, providing medical information to patients and caregivers for obtaining medications and medical treatment; Providing medical information for patients diagnosed with medical conditions regarding available resources and treatments and steps and actions for wellness, physical fitness and healthy living; providing medical counseling, mentoring and guidance for patients with medical conditions; medical services, namely, providing medical information through charitable actions in the nature of information for the continuance of medication for those who are underinsured, uninsured, or who have experienced a lapse in insurance coverage; Providing medical treatment information by text in the field of blood conditions, vaccines, and general health to patients and health care providers; Providing medical treatment information by email in the field of blood conditions, vaccines, and general health to patients and health care providers; providing an Internet website portal featuring medical treatment information for patients and healthcare providers in the field of blood conditions, vaccines and general health

Produits et services

Medical services, namely, providing medical information concerning blood products, providing medical information concerning pharmaceutical products, including providing information on preparing and self-administering medications; health care, namely, providing health care information by telephone, the internet, and through the distribution of printed matter; charitable services, namely, providing medical information to patients and caregivers for obtaining medications and medical treatment; Providing medical information for patients diagnosed with medical conditions regarding available resources and treatments and steps and actions for wellness, physical fitness and healthy living; providing medical counseling, mentoring and guidance for patients with medical conditions; medical services, namely, providing medical information through charitable actions in the nature of information for the continuance of medication for those who are underinsured, uninsured, or who have experienced a lapse in insurance coverage

Produits et services

Electronic downloadable publications, namely, booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals in the field of science and medicine; Downloadable software in the nature of a mobile application for healthcare messaging to patients and healthcare providers; Downloadable electronic publications in the nature of booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals, patients and caregivers in the field of medicine Printed publications, namely, booklets, manuals, brochures, letters, informational flyers in the field of medicine; Printed educational publications, namely, booklets, manuals, brochures, letters, informational flyers in the fields of medicine and healthcare; Printed instructional, educational, and teaching materials in the field of medicine; Printed instructional, educational, and teaching materials in the field of medicine for use by medical professionals, patients and caregivers

Produits et services

Electronic downloadable publications, namely, booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals in the field of science and medicine; Downloadable software in the nature of a mobile application for healthcare messaging to patients and healthcare providers; Downloadable electronic publications in the nature of booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals, patients and caregivers in the field of medicine Printed publications, namely, booklets, manuals, brochures, letters, informational flyers in the field of medicine; Printed educational publications, namely, booklets, manuals, brochures, letters, informational flyers in the fields of medicine and healthcare; Printed instructional, educational, and teaching materials in the field of medicine; Printed instructional, educational, and teaching materials in the field of medicine for use by medical professionals, patients and caregivers

Produits et services

Electronic downloadable publications, namely, booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals in the field of science and medicine; Downloadable software in the nature of a mobile application for healthcare messaging to patients and healthcare providers; Downloadable electronic publications in the nature of booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals, patients and caregivers in the field of medicine Printed publications, namely, booklets, manuals, brochures, letters, informational flyers in the field of medicine; Printed educational publications, namely, booklets, manuals, brochures, letters, informational flyers in the fields of medicine and healthcare; Printed instructional, educational, and teaching materials in the field of medicine; Printed instructional, educational, and teaching materials in the field of medicine for use by medical professionals, patients and caregivers

Produits et services

Downloadable electronic publications in the nature of booklets, manuals, brochures, informational letters, informational flyers, teaching materials and forms for use by medical professionals, patients and caregivers in the field of medicine; Electronic downloadable publications, namely, booklets, manuals, brochures, informational letters, informational flyers, teaching materials and forms for use by medical professionals in the field of science and medicine; Downloadable software in the nature of a mobile application for electronic messaging to patients and healthcare providers in the field of healthcare Printed publications, namely, booklets, manuals, brochures, informational letters, and informational flyers in the field of medicine; Printed educational publications, namely, booklets, manuals, brochures, informational letters, and informational flyers in the fields of medicine and healthcare; Printed instructional, educational, and teaching materials in the field of medicine; Printed instructional and teaching materials in the field of medicine for use by medical professionals, patients and caregivers

Produits et services

Electronic downloadable publications, namely, booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals in the field of science and medicine; Downloadable software in the nature of a mobile application for healthcare messaging to patients and healthcare providers; Downloadable electronic publications in the nature of booklets, manuals, brochures, letters, informational flyers, teaching materials and forms for use by medical professionals, patients and caregivers in the field of medicine Printed publications, namely, booklets, manuals, brochures, letters, informational flyers in the field of medicine; Printed educational publications, namely, booklets, manuals, brochures, letters, informational flyers in the fields of medicine and healthcare; Printed instructional, educational, and teaching materials in the field of medicine; Printed instructional, educational, and teaching materials in the field of medicine for use by medical professionals, patients and caregivers

Produits et services

Provision of educational services relating to health; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Provision of educational services relating to health; publication of the results of clinical trials; education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing information about the results of clinical trials for pharmaceutical products; providing scientific information in the field of medical disorders and their treatment. Provision of pharmaceutical information; provision of medical information.

Abrégé

The present disclosure relates generally to the manufacturing of gene therapy products, and specifically to methods of purifying an enveloped virus from a cell culture fluid, comprising an endonuclease and/or anion exchange chromatography.

Classes IPC  ?

• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification
• B01D 15/20 - Adsorption sélective, p. ex. chromatographie caractérisée par des caractéristiques de structure ou de fonctionnement relatives au conditionnement de la matière adsorbante ou absorbante
• B01D 15/36 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction ionique, p. ex. échange d'ions, paire d'ions, suppression d'ions ou exclusion d'ions
• B01D 15/42 - Adsorption sélective, p. ex. chromatographie caractérisée par le mode de développement, p. ex. par déplacement ou par élution
• B01D 61/14 - UltrafiltrationMicrofiltration
• C12N 9/22 - Ribonucléases

Produits et services

Provision of educational services relating to health; publication of the results of clinical trials; education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing information about the results of clinical trials for pharmaceutical products; providing scientific information in the field of medical disorders and their treatment. Provision of pharmaceutical information; provision of medical information.

Abrégé

Described are human serum albumin (hSA) preparations prepared from human plasma and methods of preparing them. The preparations have an amount of C1 esterase (C1E) inhibitor activity and exhibit stability against serine protease activity.

Classes IPC  ?

• C07K 14/765 - Sérum albumine, p. ex. HSA
• C07K 1/14 - ExtractionSéparationPurification
• C07K 1/18 - Chromatographie d'échange d'ions

Produits et services

Electronic data collection and data submission services for business purposes in the fields of medicine, healthcare and research; providing business intelligence services in the fields of medical devices, pharmaceuticals and life sciences from an on-line database; providing business intelligence services in the fields of pharmaceuticals and the life sciences. Custom biomanufacturing, namely, custom manufacturing of pharmaceuticals; custom biomanufacturing of biological preparations; custom manufacture of pharmaceuticals; custom manufacturing services, namely, fractionation services for others; consulting services in the field of custom biomanufacturing of pharmaceuticals, biopharmaceuticals, and fractionation. Scientific, pharmaceutical and medical research and development; biological research; scientific, pharmaceutical, and medical research platform services featuring bioproduction and regulatory pathway services; regulatory and process pathway consulting for clinical manufacturing (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); technological consulting for clinical manufacturing; research on the subject of pharmaceuticals; pharmaceutical drug development services; pharmaceutical research and development; pharmaceutical products development; providing medical research information in the field of pharmaceuticals; providing scientific research information in the field of pharmaceuticals; conducting early evaluations in the field of new pharmaceuticals; pharmaceutical product evaluation; research and development services relating to pharmaceuticals and medicines; development of pharmaceutical preparations and medicines; providing medical and scientific research information in the fields of pharmaceuticals; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; consulting services in the field of pharmaceutical and medicinal research; consulting services in the field of pharmaceutical research and development; consulting services in the field of biotechnology. Regulatory compliance consulting in the field of biotechnology; providing information about legal eligibility requirements for government medical and pharmaceutical programs; regulatory compliance consulting in the field of pharmaceuticals.

Produits et services

Electronic data collection and data submission services for business purposes in the fields of medicine, healthcare and research; providing business intelligence services in the fields of medical devices, pharmaceuticals and life sciences from an on-line database; providing business intelligence services in the fields of pharmaceuticals and the life sciences. Custom biomanufacturing, namely, custom manufacturing of pharmaceuticals; custom biomanufacturing of biological preparations; custom manufacture of pharmaceuticals; custom manufacturing services, namely, fractionation services for others; consulting services in the field of custom biomanufacturing of pharmaceuticals, biopharmaceuticals, and fractionation. Scientific, pharmaceutical and medical research and development; biological research; scientific, pharmaceutical, and medical research platform services featuring bioproduction and regulatory pathway services; regulatory and process pathway consulting for clinical manufacturing (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); technological consulting for clinical manufacturing; research on the subject of pharmaceuticals; pharmaceutical drug development services; pharmaceutical research and development; pharmaceutical products development; providing medical research information in the field of pharmaceuticals; providing scientific research information in the field of pharmaceuticals; conducting early evaluations in the field of new pharmaceuticals; pharmaceutical product evaluation; research and development services relating to pharmaceuticals and medicines; development of pharmaceutical preparations and medicines; providing medical and scientific research information in the fields of pharmaceuticals; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; consulting services in the field of pharmaceutical and medicinal research; consulting services in the field of pharmaceutical research and development; consulting services in the field of biotechnology. Regulatory compliance consulting in the field of biotechnology; regulatory compliance consulting in the field of pharmaceuticals; providing information about legal eligibility requirements for government medical and pharmaceutical programs.

Abrégé

A wash rack (100) for cleaning filter plates is described. The wash rack comprises a front face spray assembly comprising a plurality of fixed front spray nozzles (110) spaced along a first axis and a rear face spray assembly comprising a plurality of fixed rear spray nozzles (120) along a second axis for directing cleaning fluid spray towards the front and rear surfaces of a filter plate positioned therebetween.

Classes IPC  ?

• B08B 3/02 - Nettoyage par la force de jets ou de pulvérisations
• B01D 41/04 - Régénération, à l'extérieur du filtre, de la substance filtrante ou des éléments filtrants utilisés dans la filtration des fluides liquides ou gazeux d'une substance filtrante rigide ne nécessitant pas de support auxiliaire

Produits et services

Provision of educational services relating to health; publication of the results of clinical trials; education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing information about the results of clinical trials for pharmaceutical products; providing scientific information in the field of medical disorders and their treatment. Provision of pharmaceutical information; provision of medical information.

Produits et services

Provision of educational services relating to health; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials. Provision of pharmaceutical information; Provision of medical information.

Abrégé

The invention provides a method for the treatment of Ph+ leukemia in a patient comprising administering to the patient (i) a BCR-ABL tyrosine kinase inhibitor, and (ii) an agent which selectively binds to a cell surface receptor expressed on Ph+ leukemic stem cells. The invention further provides for the use of (i) and (ii) in, or in the manufacture of a medicament for, the treatment of Ph+ leukemia in a patient; and a composition for the treatment of Ph+ leukemia in a patient comprising (i) and (ii); and kits comprising (i) and (ii). In some embodiments, the tyrosine kinase inhibitor is or is not imatinib; or is selected from the group consisting of dasatinib, nilotinib, bosutinib, axitinib, cediranib, crizotinib, damnacanthal, gefitinib, lapatinib, lestaurtinib, neratinib, semaxanib, sunitinib, toceranib, tyrphostins, vandetanib, vatalanib, INNO-406, AP24534, XL228, PHA-739358, MK-0457, SGX393 and DC2036; or is selected from the group consisting of dasatinib and nilotinib. In some embodiments, the agent binds to a receptor involved in signalling by at least one of IL-3, G-CSF and GM-CSF. In some embodiments, the agent is a mutein selected from the group consisting of IL-3 muteins, G-CSF muteins and GM-CSF muteins. In some embodiments, the mutein is an IL-3 mutein. In some embodiments, the agent is a soluble receptor which is capable of binding to IL-3.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
• A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles
• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 38/19 - CytokinesLymphokinesInterférons
• A61K 38/20 - Interleukines
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
• A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc

Abrégé

The present invention relates to reconstituted high density lipoprotein (rHDL) formulations comprising an apolipoprotein, a lipid and a lyophilization stabilizer. Said formulations have reduced renal toxicity and good long-term stability, especially in lyophilized form.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/19 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres lyophilisées
• A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
• A61K 47/24 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p. ex. cyclométhicone ou phospholipides
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• C07K 14/775 - Apolipopeptides

Produits et services

(1) Provision of educational services relating to health; publication of the results of clinical trials; education services relating to therapeutic treatments. (2) Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing information about the results of clinical trials for pharmaceutical products; providing scientific information in the field of medical disorders and their treatment. (3) Provision of pharmaceutical information; provision of medical information.

Abrégé

The invention relates to methods for monitoring of parameters in solutions or suspensions and the application of same in methods for purifying solutions comprising human plasma proteins and other components. In one aspect, the invention provides a method for determining the concentration of an analyte in a sample obtained from processing of blood-derived plasma, the method comprising applying a light source to a test sample obtained from processing of blood-derived plasma; measuring inelastic scattering or Raman shift from the test sample, thereby generating test spectra and predictive models, comparing the test spectra with reference spectra obtained from reference samples having known concentrations of the analyte, to determine the concentration of the analyte in the sample.

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman
• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang

Produits et services

Pharmaceuticals.

Abrégé

The present disclosure provides proteins comprising antigen binding domains of antibodies that bind to human granulocyte-colony stimulating factor receptor.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Produits et services

Pharmaceutical preparations to treat deficiencies of Alpha One Proteinase inhibitors; Pharmaceutical preparations for transplant conditions; Pharmaceutical preparations for renal conditions; Pharmaceutical preparations for treatment of rejection in transplant recipients; Pharmaceutical preparations for antibody rejection conditions; Pharmaceutical preparations for treatment of emphysema, lung conditions, anti-inflammatory conditions, immunological conditions, and protein deficiencies; Pharmaceutical preparations to prevent and treat graft vs. host disease; Pharmaceutical preparations for Prevention and treatment of Primary Graft Dysfunction.

Produits et services

Pharmaceutical preparations to treat deficiencies of Alpha One Proteinase inhibitors; Pharmaceutical preparations for transplant conditions; Pharmaceutical preparations for renal conditions; Pharmaceutical preparations for treatment of rejection in transplant recipients; Pharmaceutical preparations for antibody rejection conditions; Pharmaceutical preparations for treatment of emphysema, lung conditions, anti-inflammatory conditions, immunological conditions, and protein deficiencies; Pharmaceutical preparations to prevent and treat graft vs. host disease; Pharmaceutical preparations for prevention and treatment of Primary Graft Dysfunction

Produits et services

(1) Business intelligence services (2) Electronic data collection for others for business purposes in the fields of medicine, healthcare management and medical research; (3) Custom biomanufacturing of pharmaceuticals; custom manufacture of pharmaceuticals (4) Custom biomanufacturing of biological pharmaceutical preparations; blood plasma fractionation services for others; Consulting services in the field of manufacture of pharmaceuticals, biopharmaceuticals, and blood plasma fractionation services; (5) Scientific research and development in the fields of pharmaceutical; pharmaceutical and medical research and development; biological research in the field of pharmaceuticals and clinical trials; Scientific research in the fields of pharmaceutical featuring bioproduction and regulatory pathway services via online web platform; pharmaceutical and medical research featuring bioproduction and regulatory pathway services via online web platform; Providing medical research information in the field of pharmaceuticals; Research and development in the field of pharmaceuticals and medicines; Consulting services in the field of pharmaceutical and medicinal research; Consulting services in the field of pharmaceutical research and development; Consulting services in the field of medical biotechnology research and development; (6) Conducting early evaluations in the field of new pharmaceuticals; development of pharmaceutical preparations and medicines; pharmaceutical drug development services; pharmaceutical product evaluation; pharmaceutical research and development; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; research on the subject of pharmaceuticals (7) Regulatory compliance consultancy in the field of clinical trials; Providing legal information services about legal eligibility requirements for government medical and pharmaceutical programs; (8) Regulatory compliance consultancy in the field of medical biotechnology; regulatory compliance consultancy in the field of pharmaceuticals

Produits et services

Electronic data collection and data submission services for business purposes in the fields of medicine, healthcare and research; Providing an on-line database providing business intelligence in the fields of medical devices, pharmaceuticals and life sciences; Providing business intelligence services in the fields of pharmaceuticals and the life sciences; Business consulting and management in the field of clinical trials, namely, clinical data and regulatory submission management on behalf of medical, biopharmaceutical and biotechnology companies to assist them with clinical research, clinical trials and applications for drug approval. Biomanufacturing for others, namely, manufacturing of pharmaceuticals; biomanufacturing of biological preparations; Custom manufacture of pharmaceuticals; Custom manufacturing services, namely, fractionation services for others; Consulting services relating to the aforementioned services; Manufacturing process consulting. Scientific, pharmaceutical and medical research and development; biological research; Scientific, pharmaceutical, and medical research platform services featuring bioproduction and regulatory pathway services; Research on the subject of pharmaceuticals; Pharmaceutical drug development services; Pharmaceutical research and development; Pharmaceutical products development; Providing medical research information in the field of pharmaceuticals; Providing scientific research information in the field of pharmaceuticals; Conducting early evaluations in the field of new pharmaceuticals; Pharmaceutical product evaluation; Research and development services relating to pharmaceuticals and medicines; Development of pharmaceutical preparations and medicines; Providing medical and scientific research information in the fields of pharmaceuticals; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consulting services in the field of pharmaceutical and medicinal research; Consulting services in the field of pharmaceutical research and development; Consulting services in the field of biotechnology. Regulatory compliance consulting in the field of biotechnology; Regulatory compliance consulting in the field of pharmaceuticals; Providing information about legal eligibility requirements for government medical and pharmaceutical programs; Advisory services relating to regulatory affairs.

Produits et services

Electronic data collection and data submission services for business purposes in the fields of medicine, healthcare and related research; Providing an on-line database providing business intelligence in the fields of medical devices, pharmaceuticals and life sciences; Providing business intelligence services in the fields of pharmaceuticals and the life sciences. Biomanufacturing for others, namely, manufacturing of pharmaceuticals; custom biomanufacturing of biological preparations; Custom manufacture of pharmaceuticals; Custom manufacturing services, namely, fractionation services for others. Scientific, pharmaceutical and medical research and development; biological research; Platform as a Service {PAAS} services featuring software for scientific research, pharmaceutical research, and medical research for reviewing, organizing and displaying research information in the field of bioproduction and regulatory pathway services; Research on the subject of pharmaceuticals; Pharmaceutical drug development services; Pharmaceutical research and development; Pharmaceutical products development; Providing medical research information in the field of pharmaceuticals; Providing scientific research information in the field of pharmaceuticals; Conducting early evaluations in the field of new pharmaceuticals; Pharmaceutical product evaluation; Research and development services relating to pharmaceuticals and medicines; Development of pharmaceutical preparations and medicines; Providing medical and scientific research information in the fields of pharmaceuticals; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consulting services in the field of pharmaceutical and medicinal research; Consulting services in the field of pharmaceutical research and development; Consulting services in the field of biotechnology; Consulting services in the field of pharmaceuticals, biopharmaceuticals, and fractionation. Regulatory compliance consulting in the field of biotechnology; Regulatory compliance consulting in the field of pharmaceuticals; Providing Information about legal eligibility requirements for government medical and pharmaceutical programs; Regulatory and legal process pathway consulting for clinical manufacturing.

Produits et services

Electronic data collection and data submission services for business purposes in the fields of medicine, healthcare and related research; Providing an on-line database providing business intelligence in the fields of medical devices, pharmaceuticals and life sciences; Providing business intelligence services in the fields of pharmaceuticals and the life sciences. Biomanufacturing for others, namely, manufacturing of pharmaceuticals; custom biomanufacturing of biological preparations; Custom manufacture of pharmaceuticals; Custom manufacturing services, namely, fractionation services for others. Scientific, pharmaceutical and medical research and development; biological research; Platform as a Service {PAAS} services featuring software for scientific research, pharmaceutical research, and medical research for reviewing, organizing and displaying research information in the field of bioproduction and regulatory pathway services; Research on the subject of pharmaceuticals; Pharmaceutical drug development services; Pharmaceutical research and development; Pharmaceutical products development; Providing medical research information in the field of pharmaceuticals; Providing scientific research information in the field of pharmaceuticals; Conducting early evaluations in the field of new pharmaceuticals; pharmaceutical product evaluation; Research and development services relating to pharmaceuticals and medicines; development of pharmaceutical preparations and medicines; Providing medical and scientific research information in the fields of pharmaceuticals; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consulting services in the field of pharmaceutical and medicinal research; Consulting services in the field of pharmaceutical research and development; Consulting services in the field of biotechnology; Consulting services in the field of pharmaceuticals, biopharmaceuticals, and fractionation. Regulatory compliance consulting in the field of biotechnology; Regulatory compliance consulting in the field of pharmaceuticals; Providing Information about legal eligibility requirements for government medical and pharmaceutical programs; Regulatory and legal process pathway consulting for clinical manufacturing.

Produits et services

(1) Business intelligence services (2) Electronic data collection for others for business purposes in the fields of medicine, healthcare management and medical research; (3) Custom biomanufacturing of biological pharmaceutical preparations; blood plasma fractionation services for others; Consulting services in the field of manufacture of pharmaceuticals, biopharmaceuticals, and blood plasma fractionation services; (4) Custom biomanufacturing of pharmaceuticals; custom manufacture of pharmaceuticals (5) Scientific research and development in the fields of pharmaceutical; pharmaceutical and medical research and development; biological research in the field of pharmaceuticals and clinical trials; Scientific research in the fields of pharmaceutical featuring bioproduction and regulatory pathway services via online web platform; pharmaceutical and medical research featuring bioproduction and regulatory pathway services via online web platform; Providing medical research information in the field of pharmaceuticals; Research and development in the field of pharmaceuticals and medicines; Consulting services in the field of pharmaceutical and medicinal research; Consulting services in the field of pharmaceutical research and development; Consulting services in the field of medical biotechnology research and development; (6) Conducting early evaluations in the field of new pharmaceuticals; development of pharmaceutical preparations and medicines; pharmaceutical drug development services; pharmaceutical product evaluation; pharmaceutical research and development; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; research on the subject of pharmaceuticals (7) Regulatory compliance consultancy in the field of clinical trials; Providing legal information services about legal eligibility requirements for government medical and pharmaceutical programs; (8) Regulatory compliance consultancy in the field of medical biotechnology; regulatory compliance consultancy in the field of pharmaceuticals

Produits et services

Electronic data collection and data submission services for business purposes in the fields of medicine, healthcare and research; Providing an on-line database providing business intelligence in the fields of medical devices, pharmaceuticals and life sciences; Providing business intelligence services in the fields of pharmaceuticals and the life sciences; Business consulting and management in the field of clinical trials, namely, clinical data and regulatory submission management on behalf of medical, biopharmaceutical and biotechnology companies to assist them with clinical research, clinical trials and applications for drug approval. Biomanufacturing for others, namely, manufacturing of pharmaceuticals; biomanufacturing of biological preparations; Custom manufacture of pharmaceuticals; Custom manufacturing services, namely, fractionation services for others; Consulting services relating to the aforementioned services; Manufacturing process consulting. Scientific, pharmaceutical and medical research and development; biological research; Scientific, pharmaceutical, and medical research platform services featuring bioproduction and regulatory pathway services; Research on the subject of pharmaceuticals; Pharmaceutical drug development services; Pharmaceutical research and development; Pharmaceutical products development; Providing medical research information in the field of pharmaceuticals; Providing scientific research information in the field of pharmaceuticals; Conducting early evaluations in the field of new pharmaceuticals; Pharmaceutical product evaluation; Research and development services relating to pharmaceuticals and medicines; Development of pharmaceutical preparations and medicines; Providing medical and scientific research information in the fields of pharmaceuticals; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consulting services in the field of pharmaceutical and medicinal research; Consulting services in the field of pharmaceutical research and development; Consulting services in the field of biotechnology. Regulatory compliance consulting in the field of biotechnology; Regulatory compliance consulting in the field of pharmaceuticals; Providing information about legal eligibility requirements for government medical and pharmaceutical programs; Advisory services relating to regulatory affairs.

Produits et services

(1) Downloadable booklets; downloadable digital manuals; downloadable digital newsletters; downloadable instant messaging software (2) Downloadable digital teaching materials for use by medical professionals, patients and caregivers in the field of medicine; downloadable educational materials, namely, brochures, informational flyers, for use by medical professionals, patients and caregivers in the field of medicine; downloadable mobile application software for instant messaging and online chatting for use by patients, patient community members, and healthcare providers; (3) Print letters; printed booklets; printed brochures; printed flyers; printed manuals (4) Printed educational materials for use by medical professionals, patients and caregivers in the field of medicine; (1) Cash card services; charitable services, namely, providing financial support to disadvantaged patients for the purpose of facilitating good health; financial administration of patient reimbursement programs; insurance information and consultancy; providing financial support to patients for the purchase of medications; providing information relating to financial management of patient reimbursement programs; providing insurance information and consultancy (2) Providing financial assistance to patients for the purchase of medications; providing information about charitable services which provide financial assistance programs to patients for the purchase of medications; (3) Nursing services; providing information to patients in the field of administering medications (4) Providing medical information about the analysis and processing of blood plasma and stem cells being medical services; providing health care information by telephone, SMS messaging, the internet, email, and through the distribution of printed matter in the field of patient access to medical treatment services and administering medications; providing medical information to patients and caregivers in the field of patient access to medical treatment services; providing medical information to patients and caregivers in the field of administering medications; providing medical information for patients diagnosed with medical conditions with available resources in the field of patient access to medical treatment services and administering medications; providing medical counseling, mentoring and guidance for patients with medical conditions in the field of patient access to medical treatment services and administering medications; providing information about conducting medical screening and examinations to underserved areas and underserved populations via charitable services; providing medical information by text to patients and health care providers the field of patient access to medical treatment services and administering medications; providing medical information by email to patients and health care providers the field of patient access to medical treatment services and administering medications; providing medical information for patients and healthcare providers in the field of patient access to medical treatment services and administering medications via internet website portal;

Produits et services

(1) Downloadable booklets; downloadable digital manuals; downloadable digital newsletters; downloadable instant messaging software (2) Downloadable digital teaching materials for use by medical professionals, patients and caregivers in the field of medicine; downloadable educational materials, namely, brochures, informational flyers, for use by medical professionals, patients and caregivers in the field of medicine; downloadable mobile application software for instant messaging and online chatting for use by patients, patient community members, and healthcare providers; (3) Print letters; printed booklets; printed brochures; printed flyers; printed manuals (4) Printed educational materials for use by medical professionals, patients and caregivers in the field of medicine; (1) Cash card services; charitable services, namely, providing financial support to disadvantaged patients for the purpose of facilitating good health; financial administration of patient reimbursement programs; insurance information and consultancy; providing financial support to patients for the purchase of medications; providing information relating to financial management of patient reimbursement programs; providing insurance information and consultancy (2) Providing financial assistance to patients for the purchase of medications; providing information about charitable services which provide financial assistance programs to patients for the purchase of medications; (3) Nursing services; providing information to patients in the field of administering medications (4) Providing medical information about the analysis and processing of blood plasma and stem cells being medical services; providing health care information by telephone, SMS messaging, the internet, email, and through the distribution of printed matter in the field of patient access to medical treatment services and administering medications; providing medical information to patients and caregivers in the field of patient access to medical treatment services; providing medical information to patients and caregivers in the field of administering medications; providing medical information for patients diagnosed with medical conditions with available resources in the field of patient access to medical treatment services and administering medications; providing medical counseling, mentoring and guidance for patients with medical conditions in the field of patient access to medical treatment services and administering medications; providing information about conducting medical screening and examinations to underserved areas and underserved populations via charitable services; providing medical information by text to patients and health care providers the field of patient access to medical treatment services and administering medications; providing medical information by email to patients and health care providers the field of patient access to medical treatment services and administering medications; providing medical information for patients and healthcare providers in the field of patient access to medical treatment services and administering medications via internet website portal;

Abrégé

A method including: receiving/retrieving, with one or more physical processors, a data set representing: two or more subjects, at least one numeric attribute with numeric values for the subjects, and at least one categorical attribute with category values for the subjects; defining, with the one or more physical processors, two or more slices for the respective subjects; defining, with the one or more physical processors, numeric-value markers for sectors with respective selected radial lengths/areas representing the numeric values; defining, with the one or more physical processors, category markers for the sectors with respective selected radii, patterns and/or colours representing the category values and mutually distinguishing the categorical values; and rendering, with the one or more physical processors, a radial bar graph from the data set, including: rendering the slices in a circle, rendering the numeric-value markers with the numeric-value radial lengths/areas in respective sectors in the circle, and rendering the category markers with the category radii, the category patterns and/or the category colours around the circle.

Classes IPC  ?

• G06F 3/04845 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p. ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs pour la transformation d’images, p. ex. glissement, rotation, agrandissement ou changement de couleur
• G06F 3/04847 - Techniques d’interaction pour la commande des valeurs des paramètres, p. ex. interaction avec des règles ou des cadrans
• G06F 16/26 - Exploration de données visuellesNavigation dans des données structurées
• G06F 3/04842 - Sélection des objets affichés ou des éléments de texte affichés
• G06F 17/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des fonctions spécifiques

Abrégé

Methods and compositions are disclosed for treating disorders of the contact activation system, comprising the administration of at least one C1-Inhibitor (C1-INH) and at least one Factor XII (FXII) inhibitor.

Classes IPC  ?

• A61K 38/57 - Inhibiteurs de protéases provenant d'animauxInhibiteurs de protéases provenant d'humains
• A61K 31/4365 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique ayant le soufre comme hétéro-atome du cycle, p. ex. ticlopidine
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61K 31/616 - Acide salicyliqueSes dérivés ayant le groupe hydroxyle en position 2 estérifié, p. ex. acide salicylsulfurique par des acides carboxyliques, p. ex. acide acétylsalicylique
• A61K 31/727 - HéparineHéparane
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• C07K 16/36 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des facteurs de coagulation sanguine

Abrégé

This disclosure relates generally to viral vectors useful for gene therapy applications. In particular the disclosure relates to lentiviral vectors, especially lentiviral vectors comprising modified insulator sequences.

Classes IPC  ?

• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C12N 15/867 - Vecteurs rétroviraux

Produits et services

Provision of educational services relating to health; Publication of the results of clinical trials; Education services relating to therapeutic treatments. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Providing information about the results of clinical trials for pharmaceutical products; Providing scientific information in the field of medical disorders and their treatment. Provision of pharmaceutical information; Provision of medical information.

Produits et services

Business management; Business management advice; Business management analysis; Business management and organization consultancy; Business management consulting; Business management planning; Employment recruiting consultation; Employment recruiting services; Employment staffing consultation services; Providing an on-line searchable database featuring employment opportunities; Providing an on-line searchable database featuring employment opportunities and content about employment; Providing networking opportunities for individuals seeking employment

Produits et services

Business management; Business management advice; Business management analysis; Business management and organization consultancy; Business management consulting; Business management planning; Employment recruiting consultation; Employment recruiting services; Employment staffing consultation services; Providing an on-line searchable database featuring employment opportunities and content about employment; Providing networking opportunities for individuals seeking employment

Produits et services

Providing information regarding medical billing support services, namely, medical records coding services for others in the nature of assignment of diagnostic and procedural codes for purposes of reimbursement from insurance Providing information regarding patient medication reimbursement programs and insurance coverage, namely, reimbursement for immunoglobulin purchases Providing medical information regarding immunoglobulin, immunodeficiency disorders, and treatment of same using immunoglobulin; medical consultation directed toward provision of letters of medical necessity or appeal

Produits et services

providing access to a portal interface for healthcare practitioners and their patients to exchange personal medical information to track their patient support program; providing information on the access to a portal interface for healthcare practitioners and their patients to exchange personal medical information to track their patient support program. Medical services relating to the removal, treatment and processing of human blood; Providing medical support in the monitoring of patients receiving medical treatments; Psychological counselling; Medical counseling services; Advisory services relating to medical services.

Produits et services

Chemical and biological reagents for industrial use for anti-body screening, blood grouping, and for the typing and detection of specific blood cells, determining the presence of antigens on blood cells, and the detection of relevant compliment components and immunoglobulin subtypes; cell cultures and media, namely, biological preparations for use in cell cultures other than for medical and veterinary use; cell growth media for growing cells for use in scientific research; cell media for growing cells for use in scientific research, namely, for use in the production of pharmaceuticals, vaccines, monoclonal antibodies and recombinant proteins; chemical test kits for the detection of specific blood cells, determining the presence of antigens on blood cells, and the detection of relevant compliment compounds and immunoglobulin subtypes for laboratory or research use; chemical preparations for scientific purposes and for use in industry; Chemical preparations, namely, diagnostic reagents for in vitro use in biochemistry, clinical chemistry and microbiology in the nature of reagents for use in the preparation of in vitro diagnostic kits, for scientific research use; chemical preparations, namely, monoclonal antibodies for use in invitro scientific or research use; chemical preparations for industrial use for anti-body screening, blood grouping, and the typing and detection of specific blood cells; diagnostic and testing agents for scientific or research use, namely, reagents for use in anti-body screening, blood grouping and the typing and detecting of specific blood cells; all of the foregoing are for medical purposes only.

Produits et services

Charitable services, namely, providing financial assistance to qualifying patients for out of pocket costs and insurance deductible amounts for pharmaceutical preparations for the treatment of blood or bleeding disorders

Abrégé

The present disclosure relates to optimised polynucleotides, vectors and methods of use thereof.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique

Produits et services

Promoting public awareness of blood conditions, diseases, disorders, and treatment; promoting the interests of patients with blood disorders by means of public advocacy, including through social media and events organized by others; promoting public awareness of the need for influenza immunization and vaccination programs; Business research in the field of public policy concerning policy initiatives for blood conditions and blood related diseases, its treatment and its impact on patients, patient families, caregivers and/or healthcare professionals; promoting the donation of blood and plasma by means of arranging and conducting incentive reward programs; providing public policy information in the field of blood conditions and blood related diseases, its treatment and its impact on patients, patient families, caregivers and/or healthcare professionals. Providing medical information concerning blood products for humans, especially blood proteins for therapeutic use, blood clotting agents and antihemophilic factors, fibrinogen concentrate, and pharmaceutical preparations for the treatment of blood or bleeding disorders and deficiencies of blood coagulation; providing medical information and treatment information in the field of health; medical services, namely, providing medical information concerning blood products, providing medical information concerning health products and services; health care, namely, providing health care information in person, via the internet, and through the distribution of printed matter

Abrégé

This disclosure relates to methods for preventing or reducing the risk of development of graft versus host disease (GVHD) in patients receiving hematopoietic cell transplantation (HCT) by particular methods of administering alpha-1 antitrypsin (A1AT or AAT) to patients both prior to and following and HCT procedure. The disclosure also relates to specific methods of treating acute GVHD (aGVHD) after HCT with A1AT.

Classes IPC  ?

• A61K 38/57 - Inhibiteurs de protéases provenant d'animauxInhibiteurs de protéases provenant d'humains
• A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
• A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe

Abrégé

The present invention provides a composition for raising an immune response against a tumor. The composition comprises at least one tumor antigen, a saponin-based adjuvant, a TLR ligand and a Flt3 ligand.

Classes IPC  ?

• A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

An apolipoprotein formulation is provided at a fixed dosage that is efficacious in the prophylactic and/or therapeutic treatment of diseases or conditions including, but not limited to cardiovascular disease, acute coronary syndrome, atherosclerosis, unstable angina pectoris, and myocardial infarction. More particularly, the fixed dosage apolipoprotein formulation displays relatively reduced inter-patient variability compared to weight-adjusted dosages. Typically, the apolipoprotein formulation is a reconstituted high density lipoprotein formulation comprising ApoA1, one or more lipids such as phosphatidylcholine, sphingomyelin and/or phosphatidylglycerol and, optionally, a detergent such as cholate at a level that does not induce liver toxicity.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 35/14 - SangSang artificiel
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Abrégé

Reconstituted HDL formulations, methods of treatment comprising same and uses thereof are provided for treating patients after an acute myocardial infarction (MI) event. The reconstituted HDL formulations comprise an apo lipoprotein, a lipid, a detergent and a stabilizer such as sucrose. Treatment of MI patients with repeated infusions of rHDL enhance cholesterol efflux capacity and do not produce significant alterations in liver or kidney function. The MI patient may have normal kidney function or moderate renal impairment.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/192 - Acides carboxyliques, p. ex. acide valproïque ayant des groupes aromatiques, p. ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
• A61K 31/216 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides ayant des cycles aromatiques, p. ex. bénactizyne, clofibrate
• A61K 31/366 - Lactones ayant des cycles à six chaînons, p. ex. delta-lactones
• A61K 31/397 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à quatre chaînons, p. ex. azétidine
• A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
• A61K 31/47 - QuinoléinesIsoquinoléines
• A61K 31/505 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime
• A61K 31/685 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols un des composés hydroxylés ayant des atomes d'azote, p. ex. phosphatidylsérine, lécithine
• A61K 31/727 - HéparineHéparane
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61K 47/28 - Stéroïdes, p. ex. cholestérol, acides biliaires ou acide glycyrrhétinique
• A61P 3/06 - Antihyperlipémiants
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale

Abrégé

The present disclosure relates generally to envelope-binding proteins and their use in methods of producing and/or purifying an enveloped virus from cell culture.

Classes IPC  ?

• C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus

Abrégé

The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or specifically binds to CD131 and neutralizes signaling by interleukin (IL) 3, IL-5 and granulocyte-macrophage colony stimulating factor (GM-CSF), and uses thereof.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

in vivoin vivo transplantation.

Classes IPC  ?

• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir
• C12N 15/90 - Introduction stable d'ADN étranger dans le chromosome

Abrégé

The present disclosure relates generally to methods and compositions for modifying a target sequence in a cell comprising contacting the cell with a gene editing system, a donor template and a second-generation DNA-PK inhibitor. In other embodiments contemplated herein, the present disclosure relates to methods and compositions for modifying a target sequence in a cell, which inhibits non-homologous end joining (NHEJ), resulting in more efficient integration of a donor template into the target sequence.

Classes IPC  ?

• C12N 15/90 - Introduction stable d'ADN étranger dans le chromosome
• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 31/522 - Purines, p. ex. adénine ayant des groupes oxo liés directement à l'hétérocycle, p. ex. hypoxanthine, guanine, acyclovir

Abrégé

The present disclosure relates to landing pads, proviruses and methods of use thereof.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification

Produits et services

Electronic downloadable publications, namely, instructional and teaching material for use by medical professionals and patients in the field of science and medicine; Downloadable electronic multimedia publications in the nature of newsletters in the field of health, pharmaceuticals, and medical treatment; downloadable electronic audio visual teaching materials, namely, audio files, and multimedia files featuring information in the field of health, pharmaceuticals, and medical treatment; publications in electronically readable and downloadable form, namely, downloadable electronic publications in the nature of newsletters in the field of health, pharmaceuticals and medical treatment; electronic publications via the internet or any other computer communication network, namely, downloadable electronic publications in the nature of newsletters in the field of health, pharmaceuticals and medical treatment; downloadable educational and training communications, namely, downloadable electronic publications in the nature of newsletters in the fields of in the field of illnesses, diseases and health-related and medical therapies; downloadable electronic publications in the nature of brochures and information leaflets in the field of plasma protein biotherapeutics and blood conditions

Produits et services

Influenza vaccines for human use.

Produits et services

Influenza vaccines for human use.

Produits et services

Pharmaceuticals, medical and veterinary preparations and substances; biological and biotechnological preparations for medical use; blood plasma; blood products in this class; products derived from blood and products derived from recombinant DNA technology; vaccines; serums; antibodies; monoclonal antibodies; reagent red blood cells; test kits in this class; chemical preparations for testing blood for medical purposes; diagnostic preparations and materials, for medical and veterinary purposes; medical dressings, coverings and applicators. Computer software; application software; downloadable software applications; software as a medical device [SaMD], downloadable; computer software and programs; electronic or recorded multimedia publications; publications sold in an electronic format and publications provided or distributed on line; electronic audio visual teaching materials; printed publications in electronically readable or downloadable form; electronic publications provided on line, from the internet or from any other communication network; educational materials in the form of computer software and programs, including applications for use on mobile devices; educational materials in the form of pre-recorded media including discs, dvds, compact discs, flash drives; all aforementioned goods in the fields of pharmacy, medicine and/or medical technology. Surgical and medical apparatus and instruments; implantable medical devices; analysis apparatus and instruments in this class; test kits in this class. Printed matter and publications; instructional and teaching material; journals, brochures, pamphlets, flyers, posters; all aforementioned goods in the fields of pharmacy, medicine and/or medical technology. Advertising, marketing and promotion services in the fields of pharmacy, medicine and/or medical technology; advertising services to promote public awareness of medical conditions; automated processing of medical data; compilation of statistical data relating to medical research; computerized management of medical records and file; medical cost management; medical transcription services; administrative services for medical referrals; business management services in this class related to the manufacture, marketing and distribution of pharmaceutical products and medical products and supplies and medical technological products; retail and wholesale services including retail and wholesale services for pharmaceutical products and medical products and supplies, veterinary and sanitary preparations and medical supplies and medical technological products. Treatment of waste materials in the fields of pharmacy, medicine and/or medical technology; recycling of medical waste; treatment of biological products including custom manufacturing and fractionation of blood; production of reagents and ancillary products for immunohaematology laboratories; processing of human blood plasma, namely, removing whole blood and separating red blood cells from plasma; treatment of human blood and plasma; fractionation of human blood and plasma; manufacturing of human blood and plasma; custom manufacture of medical devices for others. Education services including medical education services; health education; consultancy services relating to education; provision of education services via an online forum; provision of training and education courses; publication of educational materials; dissemination of educational material; weblog (blog) services; electronic publication of information on a wide range of topics, including online and over a global computer network; all aforementioned services in the fields of pharmacy, medicine and/or medical technology; organisation of conferences and symposia in the field of medical science; publication of medical publications publishing and issuing scientific papers in relation to medical technology. Scientific and technological services in the fields of pharmacy, medicine and/or medical technology; research and development services in the fields of pharmacy, medicine and/or medical technology, including scientific, medical, pharmaceutical and blood products research and development services; clinical trials; conducting clinical trials; provision of testing facilities in the fields of pharmacy, medicine and/or medical technology; rental of research facilities in the fields of pharmacy, medicine and/or medical technology; laboratory analysis and research in the fields of pharmacy and medicine; management of scientific research projects in the fields of pharmacy, medicine and/or medical technology; preparation of technical studies, technical reports, scientific reports in the fields of pharmacy, medicine and/or medical technology; preparation of scientific research projects in the fields of pharmacy, medicine and/or medical technology; preparation of statistics or reports relating to scientific research in the fields of pharmacy, medicine and/or medical technology; preparation of statistics or reports relating to medical research; preparation of medical research projects; provision of research services and facilities, provision of research results, information and outcomes in the fields of pharmacy, medicine and/or medical technology; provision of information relating to the aforementioned services; advisory and consultancy services relating to the aforementioned services; dissemination of information relating to the aforementioned services over a global computer network; medical laboratory services, namely, scientific testing and screening services, namely, testing of human blood plasma for safety and quality; medical laboratory services regarding human blood plasma; medical analysis services relating to the treatment of patients; medical consultancy services. Medical services; medical information services; health care services; health care information services; medical diagnostic services; patient support services; medical, pharmaceutical and blood products advice and consultancy services; medical advisory services; information services concerning pharmaceuticals, medical products and blood products; dissemination of information regarding the aforementioned services over a global computer network; blood bank services; operating blood and plasma collection centres; medical testing and screening services; medical testing of human blood plasma; collection, processing and testing of human blood and plasma.