Abrégé

A catheter placement system for drawing a medical tube through a sheath includes a suction generation device and further includes one or more suction adapter devices that enable connection of the suction generation device to the sheath and facilitate insertion of the medical tube into the sheath. The one or more suction adapter devices are operable for lateral removal from the sheath and the medical tube, enabling connection of the medical tube to one or more external devices prior to drawing the medical tube through the sheath.

Classes IPC  ?

• A61M 1/00 - Dispositifs de succion ou de pompage à usage médicalDispositifs pour retirer, traiter ou transporter les liquides du corpsSystèmes de drainage
• A61M 25/01 - Introduction, guidage, avance, mise en place ou maintien en position des cathéters

Abrégé

A device is disclosed that secures a capsule and accommodates puncturing of the capsule and extraction of a medication. The device includes a cavity that receives and secures the capsule. The device includes at least one opening that provides access to the cavity for extraction of the capsule contents.

Classes IPC  ?

• A61J 1/20 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue
• A61J 7/00 - Dispositifs pour administrer les médicaments par voie buccale, p. ex. cuillèresDispositifs pour compter les pilulesDispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments

Abrégé

An anonymous database system includes a plurality of biometric nodes in communication with one another. Each of the plurality of biometric nodes includes a biometric input that receives biometric data from a user. The system also includes at least one central database in communication with the plurality of biometric nodes; and a plurality of institution databases in communication with the plurality of biometric nodes. A first node of the plurality of biometric nodes is configured to receive a message from a second node of the plurality of biometric nodes, the message requesting authorization of data access by the second node. Various embodiments relate to a method for performing an action requiring multiple levels of authentication using an anonymous database system.

Classes IPC  ?

• H04L 9/40 - Protocoles réseaux de sécurité
• G06F 16/951 - IndexationTechniques d’exploration du Web
• G06F 21/32 - Authentification de l’utilisateur par données biométriques, p. ex. empreintes digitales, balayages de l’iris ou empreintes vocales
• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès

Abrégé

Described herein is an incontinence treatment system and method of use. In certain embodiments the incontinence treatment system comprises a rear incontinence member capable of being releasably coupled to a front incontinence member. For example, in one certain embodiment the rear incontinence member includes a rear absorbent region, a rear outer layer coupled to the rear absorbent region, and a plurality of coupling members. The front incontinence member typically includes a front absorbent region and a front outer layer coupled to the front absorbent region, a support material being disposed around at least a portion of the front absorbent region, and one or more coupling regions being configured and arranged to engage at least a portion of the plurality of coupling members to couple the rear incontinence member to the front incontinence member.

Classes IPC  ?

• A61F 13/495 - Garnitures absorbantes, p. ex. serviettes ou tampons hygiéniques pour application externe ou interne au corpsMoyens pour les maintenir en place ou les fixerApplicateurs de tampons caractérisées par la forme spécialement adaptées pour être portées autour de la taille, p. ex. couches-culottes avec une cavité fécale
• A61F 13/56 - Moyens pour les maintenir en place ou les fixer

Abrégé

A system for inserting a medical tube within the body using a tunneler device enables formation of a tunnel within the body and further enables concurrent insertion of the medical tube within the body as the tunnel is formed, eliminating extra steps required by current technologies for insertion of the medical tube within the body. The tunneler device provides an attachment element that captures the medical tube and further provides a handle slidably mounted along the tunneler device to aid practitioners when inserting the tunneler device into the body. The tunneler device further provides a bend angle to aid practitioners in forming the tunnel past the clavicle of the body. The tunneler device enables practitioners to place medical tubes within the body while reducing time and friction commonly associated with medical tube placement procedures.

Classes IPC  ?

• A61B 17/3205 - Instruments pour l'excision
• A61B 17/32 - Instruments chirurgicaux coupants
• A61M 27/00 - Appareillage pour drainage des blessures

Abrégé

Compositions for increasing the expression of ACMSD in a target cell and methods of using the compositions to provide a general protective effect in a cell or tissue in a subject, or protect a subject from or treating a disease condition associated with inflammation, oxidative stress, protein aggregation, energy failure, toxic exposure such as exposure to pollutants, or any combination thereof.

Classes IPC  ?

• A61K 38/51 - Lyases (4)
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• C12N 9/88 - Lyases (4.)
• C12N 15/86 - Vecteurs viraux

Abrégé

A device applies standardized central and peripheral stimuli to a patient for assessment of consciousness. The device is hand-held and includes a first stimulus element for application of peripheral stimuli to a digit (e.g., a finger or a toe) of the patient and a second stimulus element for application of central stimuli to the patient, enabling practitioners to rapidly switch between peripheral and central stimulus application. The device can generate a standardized electrical stimulus, thermal stimulus, and/or mechanical stimulus for application for improved accuracy when assessing consciousness of the patient by methods such as the Glasgow Coma Scale. In another aspect, the device applies standardized stimuli at an appropriate intensity to elicit a response without causing tissue damage.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

Abrégé

The present disclosure describes methods of determining a treatment protocol for and/or a prognosis for a subject suspected of or at risk of suffering from a neurologic disease or disorder, including such diseases and disorders that involve motor neuron function such as ALS. The methods comprise detecting the presence of a chitinase protein in a biological sample.

Classes IPC  ?

• G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes

Abrégé

pertussis toxin to the individual.

Classes IPC  ?

• A61K 38/45 - Transférases (2)
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur

Abrégé

Various embodiments of a device for deep surgical corridor microvascular anastomosis are described herein.

Classes IPC  ?

• A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose

Abrégé

A system applies a monoscopic photogrammetry process that transforms 2D high resolution anatomical images into volumetric surface reconstructions. The system includes a neural network capable of monoscopic depth estimation to generate a set of depth estimation data from a 2D anatomical image. The system then transforms the depth map into a navigable 3D model for display within an extended reality environment.

Classes IPC  ?

• A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
• A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
• A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
• G06N 3/02 - Réseaux neuronaux
• G06T 7/50 - Récupération de la profondeur ou de la forme
• G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
• G06T 17/20 - Description filaire, p. ex. polygonalisation ou tessellation
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
• A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
• G01B 11/02 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur
• G01C 11/02 - Dispositions de prises de vues spécialement adaptées pour la photogrammétrie ou les levers photographiques, p. ex. pour commander le recouvrement des photos
• G06F 3/04815 - Interaction s’effectuant dans un environnement basé sur des métaphores ou des objets avec un affichage tridimensionnel, p. ex. modification du point de vue de l’utilisateur par rapport à l’environnement ou l’objet
• G06T 3/10 - Sélection de méthodes de transformation en fonction de caractéristiques des images d’entrée
• G06T 11/00 - Génération d'images bidimensionnelles [2D]
• G06T 15/00 - Rendu d'images tridimensionnelles [3D]
• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie

Abrégé

A system includes a device associated with an endoscopy guided procedure including a housing defining a housing channel with at least a portion of the housing configured for deployment within a cavity. The device further includes a plurality of bodies defining respective channels defined within the housing. The housing defines a longitudinal axis, and the plurality of channels extends throughout the housing around the longitudinal axis. Each of the plurality of channels accommodates selective activation of radiation emittance from a predetermined different position along the housing via one or more radiation elements such that the plurality of channels collectively provides a predetermined spatial distribution of a radiation treatment to a target area along the cavity.

Classes IPC  ?

• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules
• A61M 25/09 - Fils de guidage
• A61M 25/10 - Cathéters à ballon

Abrégé

A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil

Abrégé

Various embodiments of a dural elevating and cutting apparatus and methods of use are disclosed herein.

Classes IPC  ?

• A61B 17/3211 - Scalpels chirurgicaux ou bistourisLeurs accessoires
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

Various embodiments of a spinal shield having a shield body including a plurality of lateral extensions configured to be positioned over an exposed spinal canal for establishing a protective barrier around the contents of the exposed spinal canal are disclosed.

Classes IPC  ?

• A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs

Abrégé

A modular electrode system for therapeutic application of an electric field to a tissue is described. The modular electrode system includes a flexible scaffold that conforms to a variable convex or concave surface such as a resected tissue cavity or other target tissue area and includes one or more surface electrodes in addition to one or more depth electrodes. The modular electrode system includes a control system that communicates with the plurality of electrodes of the flexible scaffold to deliver a stimulating voltage and receive measured voltage values for real-time optimization of the electric field generated within the tissue.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/02 - ÉlectrothérapieCircuits à cet effet Parties constitutives
• A61N 1/04 - Électrodes

Abrégé

Electric field therapy requires the strategic delivery of electrical energy to living tissue. Machine learning in the context of a computer-implemented planning environment can be adopted to enhance planning, monitoring, and modulation of this therapy.

Classes IPC  ?

• A61N 1/40 - Application de champs électriques par couplage inductif ou capacitif
• A61B 5/0536 - Imagerie par impédance, p. ex. par tomographie
• A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
• G06T 17/20 - Description filaire, p. ex. polygonalisation ou tessellation
• G06V 10/70 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique

Abrégé

A multidimensional tracking system incorporates observed positions of objects tracked within various virtual spaces recorded by a plurality of hierarchical tracking systems based on observable positional relationships between the plurality of hierarchical tracking systems. In one embodiment, the multidimensional tracking system displays and records tracking and manipulation of physical objects over time relative to a virtual space. Further, the multidimensional tracking system can evaluate the accuracy of observed positions of objects as well as mappings that translate each virtual space to one another based on observable positional relationships between tracked objects.

Classes IPC  ?

• A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques

Abrégé

A catheter system for draining a bodily fluid from a fluid source in a body of a subject. In one form, the catheter tube has a proximal end and a distal end. The catheter tube includes a drainage lumen that extends from a proximal end opening in the proximal end to a distal end opening in the distal end. The catheter system further includes a fluid sampling component in fluid communication with the distal end opening. In some embodiments, the catheter system includes a one-way check valve. In some embodiments, the catheter system includes a balloon positioned between one or more openings.

Classes IPC  ?

• A61M 39/24 - Soupapes de retenue ou soupapes anti-retour
• A61F 5/44 - Dispositifs portés par le patient pour recueillir l'urine, les selles, les menstrues ou d'autres sécrétionsDispositifs de colostomie
• A61M 25/00 - CathétersSondes creuses

Abrégé

Various embodiments of a system and associated method for determining a volume of surgical freedom using a plurality of three-dimensional extrema points along a surgical corridor in relation to a structure of interest are disclosed herein.

Classes IPC  ?

• A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
• A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie

Abrégé

Provided herein is a method of detecting or predicting a relapse of multiple sclerosis in an individual afflicted with a form of multiple sclerosis, comprising: (a) providing a blood sample of the individual; (b) testing the blood sample to determine a protein activity or protein level, wherein the protein is Factor VIII, von Willebrand factor, or Protein C; and (c) detecting or predicting a relapse of multiple sclerosis in the individual if the protein activity or protein level is elevated compared to the protein activity or protein level in an individual not afflicted with the form of multiple sclerosis and patients' own baseline values. Also provided herein is a method of treating an individual afflicted with multiple sclerosis, who is experiencing a relapse or predicted to experience a relapse, comprising treating the individual by administering a dose of a steroid or anti-coagulation compound effective to alleviate the symptom of multiple sclerosis.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p. ex. prégnane ou progestérone substitués en position 21, p. ex. cortisone, dexaméthasone, prednisone ou aldostérone
• A61K 31/727 - HéparineHéparane
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• G01N 33/86 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir le temps de coagulation du sang

Abrégé

Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.

Classes IPC  ?

• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
• A61P 35/00 - Agents anticancéreux
• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C12N 15/86 - Vecteurs viraux

Abrégé

An implantable electrode system includes a controller device to treat apply electric field therapy (EFT) to a target structure according to specific anatomical properties of the target structure. The system enables selective association of contacts of the implantable electrode system with one or more target locations of varying tissue types within the body for application and measurement of EFT. The one or more target locations are associated with one or more anticipated tissue parameters that the implantable electrode system uses to apply and update waveform parameters to modulate EFT application from each respective contact to the one or more target locations.

Classes IPC  ?

• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
• A61N 1/378 - Alimentation en courant électrique

Abrégé

Compositions and methods for modifying the expression of one or more chitinase proteins in a target cell or tissue type are disclosed. The compositions can be used in methods of treating a disease condition associated with expression of a chitinase protein in a cell or tissue type in a subject in need thereof, such as ALS and PD.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C12N 9/42 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons bêta-glucosidiques-1, 4, p. ex. cellulase
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens

Abrégé

An apparatus for extraction of osseous tissue is disclosed. The apparatus includes a fixed portion and a clamp oriented along a generally central area of the fixed portion. The apparatus includes a first bone cutting device and a second bone cutting device coupled to the fixed portion and oriented around the clamp. The first bone cutting device and the second bone cutting device are coupled to the fixed portion using respective joints that accommodate orientations of the first bone cutting device and the second bone cutting device relative to the fixed portion along different horizontal and vertical axes. The clamp is configured to engage a first bone portion during a surgical procedure. The first bone cutting device and the second bone cutting device are configured to remove a second bone portion.

Classes IPC  ?

• A61B 17/17 - Dispositifs de guidage pour les forets
• A61B 17/15 - Leurs dispositifs de guidage
• A61B 17/16 - Instruments pour réaliser une ostéoclasieForets ou ciseaux pour osTrépans

Abrégé

Various embodiments of a system and associated method for detection of subject activity by processing video and other signals using artificial intelligence are disclosed herein. In particular, a subject monitoring system is disclosed that monitors subjects using a video-capable camera or other suitable video capture device to identify a subject's status of an individual by monitoring subject actions in real-time. The system further monitors other persons in the room with a subject to identify their actions and identities to ensure safety of the subject and facility while preventing confusion of the system as multiple individuals step in and out of frame over the course of the collected video feed. In some embodiments, the system is operable for pose estimation and facial estimation of a subject, care provider, hospital employee or a visitor (collectively, one or more subjects) to recognize actions, emotions and/or identities of each subject to determine if the subject is at risk for an adverse event or to recognize if an adverse event has already happened.

Classes IPC  ?

• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local

Abrégé

A manually-actuated fastener delivery device for coupling portions of a bodily vessel or other cylindrical structure includes a first clamp portion that carries a first joinable portion of a fastener and a second clamp portion that carries a second joinable portion of the fastener. The fastener delivery device is optimized for micro-surgical applications, and aligns the respective first and second joinable portions of the fastener in a substantially parallel arrangement prior to coupling the first and second joinable portions of the fastener together.

Classes IPC  ?

• A61B 17/115 - Agrafeuses pour réaliser une anastomose, p. ex. en une seule opération
• A61B 17/122 - Clamps ou pinces, p. ex. pour le cordon ombilical
• A61F 2/06 - Vaisseaux sanguins

Abrégé

Various embodiments of systems and methods for implantable electrode recording of an alternating electric field are disclosed herein. In particular, the system enables interradial distance-based recording of electric field differential resultant from an applied waveform between various locations within an organic structure. The determination of electric field differential between measuring contacts can enable a practitioner to create a mapping of electric field differential throughout an organic structure that can aid in understanding of how structural and material variability throughout the bodily structure affects electric field propagation through the structure.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque

Abrégé

Various embodiments of a stereotactic coordinate adjuster system and associated method for positional adjustment of components of a stereotactic system are disclosed herein. The system provides fine adjustment to the stereotactic system by providing form-fitting components that encapsulate components of the stereotactic system and allow for fine positional adjustment of an arc support member and a slide portion of the stereotactic system.

Classes IPC  ?

• A61B 90/10 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures pour la chirurgie stéréotaxique, p. ex. système stéréotaxique à cadre

Abrégé

Systems and methods for detecting deceptive intent of a subject include observing eye movements of the subject and correlating the observed movements to known baseline neurophysiological indicators of deception. A detection system may record eye movement data from the subject, compare the eye movement data to a data model comprising threshold eye movement data samples, and from the comparison make a determination whether or not the subject is lying. The detection system may create an alert if deception is detected. The eye movements detected include saccadic and intersaccadic parameters such as intersaccadic drift velocity. Measurements may be collected in situ with a field testing device, such as a non-invasive, non-contact device attached to the subject's computing device and configured to non-obtrusively record the eye movement data.

Classes IPC  ?

• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre

Abrégé

Various exemplary embodiments relate to an anonymous database system. The system includes a plurality of biometric nodes in communication with one another. Each of the plurality of biometric nodes includes a biometric input that receives biometric data from a user. The system also includes at least one central database in communication with the plurality of biometric nodes; and a plurality of institution databases in communication with the plurality of biometric nodes. A first node of the plurality of biometric nodes is configured to receive a message from a second node of the plurality of biometric nodes, the message requesting authorization of data access by the second node. Various embodiments relate to a method for performing an action requiring multiple levels of authentication using an anonymous database system.

Classes IPC  ?

• G06F 21/32 - Authentification de l’utilisateur par données biométriques, p. ex. empreintes digitales, balayages de l’iris ou empreintes vocales
• G06F 16/951 - IndexationTechniques d’exploration du Web
• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès
• H04L 9/40 - Protocoles réseaux de sécurité

Abrégé

A system provides a computer-implemented rendered visualization of a surgeon's path or “roadmap” to a particular target region during a surgical case are disclosed herein. The system includes an approach library in communication with an operating microscope that includes data related to various surgical approach sequences, or “roadmaps” to various target regions. The approach library can be populated by the system and analyzed for variance and trends, as well as provide direct or indirect instruction and guidance through a display member during a surgical case.

Classes IPC  ?

• A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition

Abrégé

Engineered adeno-associated virus (AAV) capsid proteins, each having tropism to a desired target cell or tissue type, are disclosed. Also disclosed are methods of generating the engineered proteins, libraries comprising the engineered proteins, recombinant viruses comprising the engineered proteins, and nucleic acid constructs encoding the engineered proteins.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• C12N 5/0793 - Neurones
• G16B 20/30 - Détection de sites de liaison ou de motifs

Abrégé

A system provides an electrosurgical tool that delivers an electrosurgical waveform that can be optimized for electrosurgical tasks such as cutting and cauterization of various tissues. The electrosurgical waveform can include a first electrosurgical waveform and a second electrosurgical waveform for simultaneous delivery at respective stimulating electrodes of a stimulating pathway. In some examples, the second electrosurgical waveform is phase-shifted by 180-degrees to minimize deep penetration of current through tissue. The electrosurgical tool provides a relief pathway for further minimization of deep penetration of current through tissue, and can also enable adaptive adjustment of an impedance of the relief pathway, the stimulating pathway, and/or adjustment of one or more parameters of the electrosurgical waveform.

Classes IPC  ?

• A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
• A61B 18/08 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage à l'aide de sondes chauffées électriquement
• A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
• A61B 18/14 - Sondes ou électrodes à cet effet
• A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie

Abrégé

Systems and methods for detecting a traumatic brain injury (TBI). The system comprises a sensing arrangement and a control unit. The sensing arrangement collects eye movement data of a user. The control unit is in communication with the sensing arrangement and configured to compare the eye movement data to one or more baseline measurements of eye movement dynamics. The control unit is also configured to generate an alert indicating the presence or severity of the TBI for delivery to control unit administrator if the eye movement data diverges from one or more of the baseline measurements by a threshold amount.

Classes IPC  ?

• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre

Abrégé

Various embodiments of a device for deep surgical corridor microvascular anastomosis are described herein. A device, comprising: an elongated body; a rod disposed at least partially within the channel of the elongated body; an actuator in association with the elongated body and the rod, wherein the actuator is operable to actuate the rod in a first axial direction; and a pair of coupling arms in association with the distal portion of the rod, wherein the actuator is operable to actuate the rod in a first axial direction such that the pivotable end of each coupling arm of the pair of coupling arms is consequently actuated in the first axial direction such that the pair of coupling arms are parallel with one another in a closed configuration.

Classes IPC  ?

• A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose

Abrégé

Various embodiments for an airway isolation apparatus having a wire frame that is operable for deploying an isolation drape over a subjects head to protect healthcare and other workers from contagious or otherwise harmful agents are disclosed herein. The drape frame may include a frame base. A frame channel may extend from the frame base and a frame wire may extend through the frame channel A frame opening may be defined by the frame base and the frame channel of the drape frame. A drape may be disposed in the frame opening. Accordingly, the drape frame may be deployed in place over the chest and head of a subject. The drape may cover the subjects head to isolate the mouth and nose of the subject preparatory to accessing these airways for intubation or other procedure.

Classes IPC  ?

• A61B 46/20 - Draps de chirurgie spécialement adaptés aux patients

Abrégé

An apparatus for surgical lighting is disclosed. The apparatus includes a light emitting element formed with a light source encapsulated within an outer layer. The outer layer includes a biocompatible material. A power supply is coupled to the light source. The apparatus includes an actuating mechanism that controls power from the power supply to the light source to emit light along a surgical area. The light emitting element provides enhanced illumination and other surgical advantages.

Classes IPC  ?

• A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• F21S 2/00 - Systèmes de dispositifs d'éclairage non prévus dans les groupes principaux ou , p. ex. à construction modulaire
• F21W 131/20 - Éclairage pour un usage médical
• F21Y 115/10 - Diodes électroluminescentes [LED]

Abrégé

Described herein is an assistive medical system that is designed for individuals who are impacted by Midline-Shift Syndrome. Its purpose is to help them reorient and maintain their midline position to improve posture, balance, and other cognitive functions. This is achieved through haptic-feedback mechanisms and visual cues that gently notify the user when their position has deviated from the midline orientation.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

A toothbrush system configured to be coupled to an external suction source. The toothbrush system includes a shaft with a main body with a first end and a second end, and a bristle array and a suction port arranged at the second end. The bristle array and the suction port both extend away from the shaft so that an opening of the suction port is proximal to a distal end of the bristle array. The shaft also includes a stem arranged at the first end. The stem includes a passageway that extends through the main body to provide a fluid connection to the suction port, and is configured to be coupled to the external suction source. Also, the handle is removably coupled to the shaft and includes a drive system operably coupled to the bristle array to actuate motion of the bristle array.

Classes IPC  ?

• A61C 17/024 - Dispositifs de rinçage ou insufflateurs d'air, p. ex. utilisant des jets de fluide avec un écoulement de fluide constant
• A61C 17/02 - Dispositifs de rinçage ou insufflateurs d'air, p. ex. utilisant des jets de fluide
• A61C 17/22 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues

Abrégé

Various embodiments of a system and associated method for whole-blade acquisition and phase correction for fast and robust MR imaging are disclosed herein. In particular, the system enables sampling of odd and even k-space echoes in the same k-space as well as a whole-blade phase correction strategy to achieve improved image quality at an accelerated imaging rate.

Classes IPC  ?

• G01G 3/00 - Appareils de pesée caractérisés par l'utilisation d'organes déformables par élasticité, p. ex. balances à ressort
• G01R 33/48 - Systèmes d'imagerie RMN
• G01R 33/561 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne par réduction du temps de balayage, c.-à-d. systèmes d'acquisition rapide, p. ex. utilisant des séquences d'impulsions écho-planar
• G01R 33/563 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne de matériaux en mouvement, p. ex. angiographie à écoulement contrasté

Abrégé

Various embodiments of a system and associated method for determining a volume of surgical freedom using a plurality of three-dimensional extrema points along a surgical corridor in relation to a structure of interest are disclosed herein.

Classes IPC  ?

• G06T 11/20 - Traçage à partir d'éléments de base, p. ex. de lignes ou de cercles
• G06T 19/20 - Édition d'images tridimensionnelles [3D], p. ex. modification de formes ou de couleurs, alignement d'objets ou positionnements de parties
• A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
• A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
• A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie

Abrégé

Various embodiments of a hydrophilic catheter introduction system for improved insertion of a shunt catheter are disclosed herein. The catheter introduction system includes an introducer sheath defining an inner surface that includes a hydrophilic coating to aid in passage of a catheter through the introducer sheath. Evaluation of the catheter introduction system with respect to other catheter introduction systems resulted in a significant decrease in average catheter threading time.

Classes IPC  ?

• A61M 27/00 - Appareillage pour drainage des blessures
• A61M 25/00 - CathétersSondes creuses
• A61M 25/01 - Introduction, guidage, avance, mise en place ou maintien en position des cathéters

Abrégé

Various embodiments of an expandable interbody cage device configured to reduce subsidence into an endplate of a vertebral body by including a plurality of arms that engage the cortical tissue of the vertebral body. The plurality of arms increase the surface area and improve distribution of force, especially around stronger parts of the endplate such as the cortical bone at the rim of the endplate. The expandable interbody cage device maintains a low or slim profile while in a “closed” configuration during insertion between vertebrae and is further operable to laterally expand into an “open” configuration that increases the surface area of the expandable interbody cage device after insertion to securely engage the expandable interbody cage device between the vertebra. The expandable interbody cage device further includes one or more ports and/or cavities in which bone graft material can be disposed within.

Classes IPC  ?

• A61F 2/44 - Articulations pour l'épine dorsale, p. ex. vertèbres, disques intervertébraux
• A61F 2/28 - Os
• A61F 2/30 - Articulations

Abrégé

Methods of externally reinforcing biological vessels include forming a reinforcing frame around a vessel using a pliable framing material, and applying a solidifying substance to the framing material that transitions the framing material and solidifying substance to a solid state, forming a solid encasement. The framing material can include a plurality of sheets for application in an overlapping piecemeal fashion to a vessel within a surgical corridor. The solidifying substance permeates the reinforcing frame prior to transitioning to the solid state to ensure that the resulting encasement is filly solidified.

Classes IPC  ?

• A61F 2/945 - Stents conservant leur forme, c.-à-d. non déformables, après mise en place à l’endroit voulu durcissables, p. ex. stents formés in situ
• A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles
• A61F 2/06 - Vaisseaux sanguins

Abrégé

In accordance with some embodiments of the disclosed subject matter, systems, methods, and media for selectively presenting images captured by confocal laser endomicroscopy (CLE) are provided. In some embodiments, a method comprises: receiving images captured by a CLE device during brain surgery; providing the images to a convolution neural network (CNN) trained using at least a plurality of images of brain tissue captured by a CLE device and labeled diagnostic or non-diagnostic; receiving an indication, from the CNN, likelihoods that the images are diagnostic images; determining, based on the likelihoods, which of the images are diagnostic images; and in response to determining that an image is a diagnostic image, causing the image to be presented during the brain surgery.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• G06N 3/045 - Combinaisons de réseaux
• G06N 3/08 - Méthodes d'apprentissage
• G06T 7/00 - Analyse d'image
• G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
• G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
• G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
• G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux

Abrégé

An implantable valve device includes a valve unit having a flow limiter in operative association with a dial for controlling a flow of material through a lumen in communication with the valve unit. The dial includes a dial indicator viewable through cross-sectional imaging for determining and/or otherwise verifying a "pressure setting" of the valve unit. The valve unit can include a housing that encapsulates the dial therein and provides one or more reference indicators that enable a practitioner to determine an orientation of the valve unit and further clarify the position of the dial indicator. The valve unit can be interrogated through conventional non-invasive cross-sectional imaging methods such as ultrasound.

Classes IPC  ?

• A61M 27/00 - Appareillage pour drainage des blessures
• A61M 39/22 - Soupapes ou agencement de soupapes

Abrégé

Various embodiments of a predictive double-booking system for use in medical appointment booking applications are described herein.

Classes IPC  ?

• G06Q 10/1093 - Ordonnancement basé sur un agenda pour des personnes ou des groupes
• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération

Abrégé

Disclosed are systems and compositions for reducing the expression of a CaV1.3 protein in a subject and methods of using the systems for treating dyskinesias induced by DA agonist therapy including levodopa-induced dyskinesias (LID), improving the response to levodopa, and improving the response to levodopa in a subject in need thereof; and slowing progression of Parkinson's disease by providing protection against death or dysfunction of substantia nigra dopamine neurons.

Classes IPC  ?

• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
• C12N 15/86 - Vecteurs viraux
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• A61P 25/16 - Antiparkinsoniens

Abrégé

Various embodiments of an anchor and intradiscal implant for surgical realignment of a misaligned spine are disclosed herein.

Classes IPC  ?

• A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs

Abrégé

A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.

Classes IPC  ?

• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 5/18 - Dispositifs pour l'exécution des tests de capacité pour conducteurs de véhicules
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Produits et services

Medical devices, namely, minimally invasive neurovascular devices, spine technologies being medical apparatus for spinal cord stimulation, spine devices being medical apparatus for spinal cord stimulation and related paraphernalia in the nature of spinal syringes, medical apparatus for spinal disc repair, spiral cross connectors, spinal implants composed of artificial materials for medical conditions that may benefit from a neurological or spinal treatment Educational services, namely, classes, seminars and workshops in the field of neurosciences and delivery of treatments Research services in the field of neuroscience Healthcare services; Healthcare services and particularly clinical health services being healthcare services related to the neurosciences

Abrégé

Various embodiments of a system and method for the treatment of brain cancer using a subdurally-implanted alternating electric field generation apparatus are disclosed herein.

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
• A61N 1/40 - Application de champs électriques par couplage inductif ou capacitif

Abrégé

Disclosed herein are methods for treating hot flushes in a subject. In one embodiment, treating hot flushes includes administering to a subject in need of such treatment, a therapeutically effective amount of a transient receptor potential channel (TRP channel) blocker or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods for amelioration, alleviation, or prevention of the thermal discomfort in hot flushes, comprising: selecting a subject in need of treatment for hot flushes, administering to the subject a therapeutically effective amount of a TRP channel blocker, such as a TRPV1 blocker, or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 31/17 - Amides, p. ex. acides hydroxamiques ayant le groupe N-C(O)-N ou N-C(S)-N, p. ex. urée, thiourée, carmustine
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
• A61K 31/4725 - Isoquinoléines non condensées, p. ex. papavérine contenant d'autres hétérocycles
• A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole

Abrégé

A catheter placement system for drawing a medical tube through a sheath includes a suction generation device and further includes one or more suction adapter devices that enable connection of the suction generation device to the sheath and facilitate insertion of the medical tube into the sheath. The one or more suction adapter devices are operable for lateral removal from the sheath and the medical tube, enabling connection of the medical tube to one or more external devices prior to drawing the medical tube through the sheath.

Classes IPC  ?

• A61M 1/00 - Dispositifs de succion ou de pompage à usage médicalDispositifs pour retirer, traiter ou transporter les liquides du corpsSystèmes de drainage
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

Various embodiments of a stereotactic coordinate adjuster system and associated method for positional adjustment of components of a stereotactic system are disclosed herein. The system provides fine adjustment to the stereotactic system by providing form-fitting components that encapsulate components of the stereotactic system and allow for fine positional adjustment of an arc support member and a slide portion of the stereotactic system.

Classes IPC  ?

• A61B 90/10 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures pour la chirurgie stéréotaxique, p. ex. système stéréotaxique à cadre

Abrégé

Various embodiments of a computer-implemented system for generating an algorithm configured to compute an attribution output to enhance provider attribution are disclosed.

Classes IPC  ?

• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G06N 20/00 - Apprentissage automatique

Abrégé

Various embodiments of an anatomical model suitable for microsurgical training are disclosed. The anatomical model includes predetermined ergonomic features that accommodate training of a surgical task.

Classes IPC  ?

• G09B 23/30 - Modèles anatomiques

Abrégé

Compounds and berberine compositions containing such compounds that are useful for reducing nicotine dependency. Methods for administering the berberine compositions are also disclosed. The compounds may have a structure according to Formula (I). In Formula (I) R1, R2, R3, R4, and R5 are independently H or D; R6 and R7 are independently hydrogen, deuterium, halogen, C4 to C8 unsubstituted aryl, C4 to C8 substituted aryl, C2 to C6 unsubstituted heterocycle, C2 to C6 substituted heterocycle, C1 to C6 unsubstituted alkyl, C1 to C6 substituted alkyl, C3-C10 unsubstituted cycloalkyl, C3-C10 substituted cycloalkyl, or R6 and R7 are taken together as ═O or ═S; and R8 and R9 are independently selected from a group consisting of methyl, CHF2, and CF3.

Classes IPC  ?

• C07D 455/03 - Composés hétérocycliques contenant des systèmes cycliques quinolizine, p. ex. alcaloïdes de l'émétine, protoberbérineDérivés alkylènedioxy des dibenzo [a, g] quinolizines, p. ex. berbérine contenant des systèmes cycliques quinolizine directement condensés avec au moins un carbocycle à six chaînons, p. ex. protoberbérineDérivés alkylènedioxy des dibenzo [a, g] quinolizines, p. ex. berbérine
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61P 25/34 - Médicaments pour le traitement des troubles du système nerveux des états d'abus ou de dépendance au tabac

Abrégé

Various embodiments of a catheter stabilizer that includes a retention body and an occluder for positioning within a burr hole or other channel in the body for occlusion and stabilization of a catheter during a surgical procedure are described herein.

Classes IPC  ?

• A61M 25/04 - Dispositifs de maintien en position, p. ex. sur le corps à l'intérieur du corps, p. ex. expansibles

Abrégé

Various embodiments of a system and associated method for a surgical positioning apparatus for supporting a patient in supine, lateral, kidney and prone position are disclosed herein.

Classes IPC  ?

• A61G 13/00 - Tables d'opérationLeurs accessoires
• A61G 13/06 - Tables d'opération réglablesLeurs commandes la surface totale de la table pouvant être élevée ou abaissée
• A61G 13/12 - Appuis qui leur sont spécialement adaptésDisposition des surfaces pour supporter des patients

Abrégé

Disclosed herein is a wheel shield apparatus that includes a pair of elongated parallel tube members in perpendicular engagement with a pair of short parallel tube members, at least one removable side of the wheel shield apparatus is operable to be temporarily opened or removed such that the wheel shield apparatus may be placed around a wheel of a neurosurgical microscope or some other type of heavy wheeled machinery and the removable side may be placed in a closed position such that the wheel shield surrounds the wheel. Each of the pair of elongated parallel tube members and/or each of the pair of short parallel tube members comprises a cavity configured to receive a ballast material to provide sufficient weight to ensure that the wheel shield apparatus contacts the floor such that cables along the floor are pushed out of the way by the wheel shield apparatus and prevented from being run over while the machinery is being transported.

Classes IPC  ?

• B60R 19/00 - Protège-rouesProtège-radiateursDéplaceurs d'obstaclesÉquipements amortissant la force de choc dans les collisions
• B60T 3/00 - Dispositifs portatifs pour empêcher le mouvement non voulu d'un véhicule, p. ex. cales
• B60P 3/077 - Cuvettes, cales ou cages pour roues
• B60P 7/08 - Fixation au plancher ou aux parois du véhicule
• B60B 33/00 - Roues à pivot en général
• B60R 19/54 - Déblayeurs d'obstacles ou déviateurs

Abrégé

A system for inserting a medical tube within the body using a tunneler device enables formation of a tunnel within the body and further enables concurrent insertion of the medical tube within the body as the tunnel is formed, eliminating extra steps required by current technologies for insertion of the medical tube within the body. The tunneler device provides an attachment element that captures the medical tube and further provides a handle slidably mounted along the tunneler device to aid practitioners when inserting the tunneler device into the body. The tunneler device further provides a bend angle to aid practitioners in forming the tunnel past the clavicle of the body. The tunneler device enables practitioners to place medical tubes within the body while reducing time and friction commonly associated with medical tube placement procedures.

Classes IPC  ?

• A61B 17/32 - Instruments chirurgicaux coupants

Abrégé

Systems and methods for detecting onset, presence, and progression of particular states, including intoxication, include observing eye movements of a subject and correlating the observed movements to known baseline neurophysiological indicators of intoxication. A detection system may record eye movement data from a user, compare the eye movement data to a data model comprising threshold eye movement data samples, and from the comparison make a determination whether or not intoxication or impairment is present. The detection system may alert the user to take corrective action if onset or presence of a dangerous condition is detected. The eye movements detected include saccadic and intersaccadic parameters such as intersaccadic drift velocity. Measurements may be collected in situ with a field testing device. An interactive application may be provided on a user device to provoke the desired eye movements during recording.

Classes IPC  ?

• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/18 - Dispositifs pour l'exécution des tests de capacité pour conducteurs de véhicules
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 3/113 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil

Abrégé

A device applies standardized central and peripheral stimuli to a patient for assessment of consciousness. The device is hand-held and includes a first stimulus element for application of peripheral stimuli to a digit (e.g., a finger or a toe) of the patient and a second stimulus element for application of central stimuli to the patient, enabling practitioners to rapidly switch between peripheral and central stimulus application. The device can generate a standardized electrical stimulus, thermal stimulus, and/or mechanical stimulus for application for improved accuracy when assessing consciousness of the patient by methods such as the Glasgow Coma Scale. In another aspect, the device applies standardized stimuli at an appropriate intensity to elicit a response without causing tissue damage.

Classes IPC  ?

• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques

Abrégé

Compositions for increasing the expression of ACMSD in a target cell and methods of using the compositions to provide a general protective effect in a cell or tissue in a subject, or protect a subject from or treating a disease condition associated with inflammation, oxidative stress, protein aggregation, energy failure, toxic exposure such as exposure to pollutants, or any combination thereof.

Classes IPC  ?

• C12N 15/52 - Gènes codant pour des enzymes ou des proenzymes
• A61K 38/51 - Lyases (4)
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• C12N 9/88 - Lyases (4.)
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
• C12N 15/86 - Vecteurs viraux
• C12N 15/861 - Vecteurs adénoviraux

Abrégé

A spinal implant is disclosed for engagement to portions of a spinal segment after a laminectomy procedure. The spinal implant includes a first member and a second member in orthogonal relation relative to the first member such that the spinal implant generally defines a t-shape configuration. The spinal implant is formed using biocompatible materials to safely adapt to the surgical area. The spinal implant may include hooks or apertures for engaging with portions of bodily tissue. The spinal implant may be engaged to other spinal implants along the spine using one or more arms of an interconnecting arrangement.

Classes IPC  ?

• A61B 17/70 - Dispositifs de mise en position ou de stabilisation de la colonne vertébrale, p. ex. stabilisateurs comprenant un liquide de remplissage dans un implant
• A61F 2/44 - Articulations pour l'épine dorsale, p. ex. vertèbres, disques intervertébraux
• A61F 2/30 - Articulations

Abrégé

Disclosed herein is a system/apparatus for storing, use in therapy, and transporting a (bionic) exoskeleton. The apparatus includes a frame comprising a plurality of legs, a seat, and a back which are operable for being moved between one or more configurations. The seat of the frame defines a seat surface configured for engagement with an exoskeleton. Furthermore, the back of the frame is operably engaged with the seat such that the back of the frame may be folded over, into, or extended from the frame to reduce an overall profile size of the apparatus in a collapsed or folded configuration. The apparatus may further include a pair of footrests defined along the legs that rotate in a lateral direction relative to the frame for the patients ease of transition into the exoskeleton. The frame also includes a locking mechanism that aids to from a storage configuration or a ready configuration.

Classes IPC  ?

• A61H 1/02 - Appareils d'exercice extenseurs ou de ployage
• A61G 5/10 - Parties constitutives, détails ou accessoires
• A61G 5/12 - Appuis qui leur sont spécialement adaptés, p. ex. pour la tête ou les pieds
• B25J 9/00 - Manipulateurs à commande programmée
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61G 5/08 - Fauteuils ou moyens de transport personnels spécialement adaptés pour des personnes handicapées, p. ex. fauteuils roulants pliables

Abrégé

A multidimensional tracking system incorporates observed positions of objects tracked within various virtual spaces recorded by a plurality of hierarchical tracking systems based on observable positional relationships between the plurality of hierarchical tracking systems. In one embodiment, the multidimensional tracking system displays and records tracking and manipulation of physical objects over time relative to a virtual space. Further, the multidimensional tracking system can evaluate the accuracy of observed positions of objects as well as mappings that translate each virtual space to one another based on observable positional relationships between tracked objects.

Classes IPC  ?

• G06F 15/00 - Calculateurs numériques en généralÉquipement de traitement de données en général

Abrégé

A system includes a device associated with an endoscopy guided procedure including a housing defining a housing channel with at least a portion of the housing configured for deployment within a cavity. The device further includes a plurality of bodies defining respective channels defined within the housing. The housing defines a longitudinal axis, and the plurality of channels extends throughout the housing around the longitudinal axis. Each of the plurality of channels accommodates selective activation of radiation emittance from a predetermined different position along the housing via one or more radiation elements such that the plurality of channels collectively provides a predetermined spatial distribution of a radiation treatment to a target area along the cavity.

Classes IPC  ?

• A61M 36/00 - Application de matériau radioactif au corps
• A61M 36/04 - Dispositions spécialement adaptées pour introduire, p. ex. par inhalation ou par injection, un matériau radioactif dans le corps
• A61M 36/12 - Injecteurs, supports pour pastilles ou implants, p. ex. capsules
• A61N 5/00 - Thérapie par radiations
• A61N 5/10 - RadiothérapieTraitement aux rayons gammaTraitement par irradiation de particules

Abrégé

A modular electrode system for therapeutic application of an electric field to a tissue is described. The modular electrode system includes a flexible scaffold that conforms to a variable convex or concave surface such as a resected tissue cavity or other target tissue area and includes one or more surface electrodes in addition to one or more depth electrodes. The modular electrode system includes a control system that communicates with the plurality of electrodes of the flexible scaffold to deliver a stimulating voltage and receive measured voltage values for real-time optimization of the electric field generated within the tissue.

Classes IPC  ?

• A61B 5/256 - Électrodes portables, p. ex. avec des sangles ou des bandes

Abrégé

Electric field therapy requires the strategic delivery of electrical energy to living tissue. Machine learning in the context of a computer-implemented planning environment can be adopted to enhance planning, monitoring, and modulation of this therapy.

Classes IPC  ?

• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• A61B 18/14 - Sondes ou électrodes à cet effet
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/40 - Application de champs électriques par couplage inductif ou capacitif
• G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS

Abrégé

An implantable electrode system includes a controller device to treat apply electric field therapy (EFT) to a target structure according to specific anatomical properties of the target structure. The system enables selective association of contacts of the implantable electrode system with one or more target locations of varying tissue types within the body for application and measurement of EFT. The one or more target locations are associated with one or more anticipated tissue parameters that the implantable electrode system uses to apply and update waveform parameters to modulate EFT application from each respective contact to the one or more target locations.

Classes IPC  ?

• A01N 1/05 -
• A61N 1/18 - Application de courants électriques par électrodes de contact
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs

Abrégé

A method for bending a surgical rod using an automated bending system includes receiving an indication of a plurality of line segments defined on the rod and an indication of an angle measurement to be formed between at least two adjacent ones of the plurality of line segments. Bending parameters to perform on the rod to form the angle measurement between the at least two adjacent ones of the plurality of line segments are determined and operation of the automated bending system is controlled using the bending parameters to create an angle having the angle measurement between the at least two adjacent ones of the plurality of line segments.

Classes IPC  ?

• A61B 17/88 - Moyens ou procédés pour implanter ou pour extraire des dispositifs de fixation interne
• A61B 17/70 - Dispositifs de mise en position ou de stabilisation de la colonne vertébrale, p. ex. stabilisateurs comprenant un liquide de remplissage dans un implant
• B21D 7/08 - Cintrage des barres, profilés ou tubes par passage entre des rouleaux ou à travers une matrice courbe
• B21D 7/12 - Cintrage des barres, profilés ou tubes avec une commande à programme
• B21D 7/14 - Cintrage des barres, profilés ou tubes combiné avec une mesure des courbures ou des longueurs
• B21D 43/00 - Dispositifs d'alimentation, de positionnement ou de stockage combinés à des appareils pour travailler ou traiter les tôles, les tubes ou les profilés, disposés dans ces appareils ou spécialement adaptés pour être utilisés en association avec ces appareilsAssociation de dispositifs de coupe avec ces appareils
• B21F 1/00 - Cintrage des fils métalliques autre que l'enroulementRedressage des fils métalliques
• B21F 45/00 - Travail du fil métallique pour la fabrication d'autres objets particuliers

Abrégé

Disclosed herein are compositions, methods of treatment, and uses of inhibitory interneuron precursors, derived from the brain's medial ganglionic eminence, or differentiated from iPSC or ESCs, for the treatment of pre-diabetes or diabetes. In some embodiments, compositions including inhibitory interneuron precursors are transplanted into the arcuate nucleus of the hypothalamus region of the brain, to treat, for example, diabetes, such as, type-2 diabetes, In further embodiments, inhibitory interneuron precursors are used in the manufacture of a medicament for the treatment of diabetes, for example, type-2 diabetes.

Classes IPC  ?

• A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/08 - Solutions
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques

Abrégé

A Surgical Preference Management System is used to collect and store surgical preferences (“preference cards”) specifying resources desired to perform medical tasks. Information concerning costs and surgical outcomes are continuously monitored and associated with preference cards for those tasks. Analyses of cost, outcome, and other related data are used to identify opportunities to improve outcomes, costs, and other metrics by applying suggested modifications to preference cards. Selected analysis results and suggestions are presented to users within a user interface which allows users to adopt suggestions and make other modifications which cause preference cards to be immediately updated and supplied to other connected medical systems.

Classes IPC  ?

• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients

Abrégé

Compositions and methods for modifying the expression of one or more chitinase proteins in a target cell or tissue type are disclosed. The compositions can be used in methods of treating a disease condition associated with expression of a chitinase protein in a cell or tissue type in a subject in need thereof, such as ALS and PD.

Classes IPC  ?

• C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
• A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteursVecteurs Utilisation d'hôtes pour ceux-ciRégulation de l'expression

Abrégé

Various embodiments of a spinal shield having a shield body including a plurality of lateral extensions configured to be positioned over an exposed spinal canal for establishing a protective barrier around the contents of the exposed spinal canal are disclosed.

Classes IPC  ?

• A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs

Abrégé

Various embodiments of a system and associated method for detection of subject activity by processing video and other signals using artificial intelligence are disclosed herein. In particular, a subject monitoring system is disclosed that monitors subjects using a video-capable camera or other suitable video capture device to identify a subject's status of an individual by monitoring subject actions in real-time. The system further monitors other persons in the room with a subject to identify their actions and identities to ensure safety of the subject and facility while preventing confusion of the system as multiple individuals step in and out of frame over the course of the collected video feed. In some embodiments, the system is operable for pose estimation and facial estimation of a subject, care provider, hospital employee or a visitor (collectively, one or more subjects) to recognize actions, emotions and/or identities of each subject to determine if the subject is at risk for an adverse event or to recognize if an adverse event has already happened.

Classes IPC  ?

• G08B 21/02 - Alarmes pour assurer la sécurité des personnes
• A61B 5/1171 - Identification des personnes basée sur la morphologie ou l’aspect de leur corps ou de parties de celui-ci
• G08B 21/18 - Alarmes de situation
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients

Produits et services

Downloadable digital publications in the nature of electronic books, handouts, journals, magazines, newsletters, and workbooks in the fields of health care and medicine Printed educational materials in the fields of health care and medicine; Printed publications, namely, books, handouts, journals, magazines, newsletters, and workbooks in the fields of health care and medicine Digital and print advertising and marketing services in the fields of health care, medicine and neurosciences; Advertising, marketing and promotion services in the fields of health care and medicine; Recruitment and placement of personnel in the field of health care; Health care residencies recruitment services and programs; Professional staffing and recruiting services Providing online non-downloadable digital publications in the nature of electronic books, handouts, journals, magazines, newsletters, and workbooks in the fields of health care and medicine Medical and scientific research, namely, conducting clinical trials for others; Scientific research in the nature of conducting clinical trials for others; Medical research; Medical research in the field of neuroscience; Medical laboratories; Medical laboratory services Health care services; Health care services for treating epilepsy, multiple sclerosis, ALS, strokes, Alzheimer's and memory disorders, aneurysms and cerebrovascular disorders, brain tumors, cleft palate and craniofacial disorders, concussions and traumatic brain injuries, acoustic neuroma, neuromuscular diseases, hypothalamic hamartoma, migraine and headache disorders, Parkinson's disease, movement disorders, pituitary disorders, neuro-endocrine disorders, spine disorders and injuries, brain disorders and injuries, stroke, and peripheral nerve disorders; Medical services in the fields of oncology, neuropsychology, psychology, neuroradiology, neurosurgery, neurology, ENT, otolaryngology, neurobiology, neuropathology, otolaryngology, surgery, neuro-ophthalmology, ophthalmology, neuro-otology, otology, neurotrauma, audiology, neuroscience, neurodegeneration, neuroinflammation, and neurotrauma; Advisory services relating to health care; Consultancy services relating to health care; Medical imaging services; Nursing care; Nursing services; Nursing services in the field of neuroscience; Radiation oncology services; Rehabilitation patient care services; Medical, physical rehabilitation and physical therapy services; Providing educational information about health care; Telemedicine services; Sports medicine services

Produits et services

Downloadable digital publications in the nature of electronic books, handouts, journals, magazines, newsletters, and workbooks in the fields of health care and medicine Digital and print advertising and marketing services in the fields of health care, medicine and neurosciences; Advertising, marketing and promotion services in the fields of health care and medicine; Recruitment and placement of personnel in the field of health care; Health care residencies recruitment services and programs; Professional staffing and recruiting services Providing online non-downloadable digital publications in the nature of electronic books, handouts, journals, magazines, newsletters, and workbooks in the fields of health care and medicine Medical and scientific research, namely, conducting clinical trials for others; Scientific research in the nature of conducting clinical trials for others; Medical research; Medical research in the field of neuroscience; Medical laboratories; Medical laboratory services Health care services; Health care services for treating epilepsy, multiple sclerosis, ALS, strokes, Alzheimer's and memory disorders, aneurysms and cerebrovascular disorders, brain tumors, cleft palate and craniofacial disorders, concussions and traumatic brain injuries, acoustic neuroma, neuromuscular diseases, hypothalamic hamartoma, migraine and headache disorders, Parkinson's disease, movement disorders, pituitary disorders, neuro-endocrine disorders, spine disorders and injuries, brain disorders and injuries, stroke, and peripheral nerve disorders; Medical services in the fields of oncology, neuropsychology, psychology, neuroradiology, neurosurgery, neurology, ENT, otolaryngology, neurobiology, neuropathology, otolaryngology, surgery, neuro-ophthalmology, ophthalmology, neuro-otology, otology, neurotrauma, audiology, neuroscience, neurodegeneration, neuroinflammation, and neurotrauma; Advisory services relating to health care; Consultancy services relating to health care; Medical imaging services; Nursing care; Nursing services; Nursing services in the field of neuroscience; Radiation oncology services; Rehabilitation patient care services; Medical, physical rehabilitation and physical therapy services; Providing educational information about health care; Telemedicine services; Sports medicine services

Abrégé

Various embodiments of systems and methods for implantable electrode recording of an alternating electric field are disclosed herein. In particular, the system enables interradial distance-based recording of electric field differential resultant from an applied waveform between various locations within an organic structure. The determination of electric field differential between measuring contacts can enable a practitioner to create a mapping of electric field differential throughout an organic structure that can aid in understanding of how structural and material variability throughout the bodily structure affects electric field propagation through the structure.

Classes IPC  ?

• A61N 1/02 - ÉlectrothérapieCircuits à cet effet Parties constitutives
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
• A61N 1/18 - Application de courants électriques par électrodes de contact
• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques

Abrégé

System and method for automatically bending a surgical rod are provided. The system includes a linear movement device configured to axially feed the surgical rod, a rotational movement device configured to rotate the surgical rod as it is axially fed, and a bending device including a roller to impose bending forces against the rod. The rod is free from contact with the bending device after it is axially fed past the roller.

Classes IPC  ?

• A61B 17/88 - Moyens ou procédés pour implanter ou pour extraire des dispositifs de fixation interne
• A61B 17/70 - Dispositifs de mise en position ou de stabilisation de la colonne vertébrale, p. ex. stabilisateurs comprenant un liquide de remplissage dans un implant
• B21D 7/022 - Cintrage des barres, profilés ou tubes sur un organe de formage fixeCintrage des barres, profilés ou tubes par utilisation d'un organe de formage ou d'une butée oscillante sur un organe de formage fixe uniquement
• B21D 7/08 - Cintrage des barres, profilés ou tubes par passage entre des rouleaux ou à travers une matrice courbe
• B21D 43/00 - Dispositifs d'alimentation, de positionnement ou de stockage combinés à des appareils pour travailler ou traiter les tôles, les tubes ou les profilés, disposés dans ces appareils ou spécialement adaptés pour être utilisés en association avec ces appareilsAssociation de dispositifs de coupe avec ces appareils
• B21F 1/00 - Cintrage des fils métalliques autre que l'enroulementRedressage des fils métalliques
• B21F 23/00 - Alimentation en fils métalliques des machines ou appareils traitant ce matériau
• B21F 45/00 - Travail du fil métallique pour la fabrication d'autres objets particuliers

Abrégé

Various embodiments of a coupler and an intradiscal implant for alignment and fusion of the sacroiliac joint are described herein.

Classes IPC  ?

• A61F 2/30 - Articulations
• A61F 2/28 - Os

Abrégé

Various embodiments of a device for deep surgical corridor microvascular anastomosis are described herein. A device, comprising: an elongated body; a rod disposed at least partially within the channel of the elongated body; an actuator in association with the elongated body and the rod, wherein the actuator is operable to actuate the rod in a first axial direction; and a pair of coupling arms in association with the distal portion of the rod, wherein the actuator is operable to actuate the rod in a first axial direction such that the pivotable end of each coupling arm of the pair of coupling arms is consequently actuated in the first axial direction such that the pair of coupling arms are parallel with one another in a closed configuration.

Classes IPC  ?

• A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
• A61B 17/04 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour la suture des plaiesSupports ou emballages pour aiguilles ou matériaux de suture
• A61B 17/115 - Agrafeuses pour réaliser une anastomose, p. ex. en une seule opération

Abrégé

A system and method for coordinating physician matching for a user. The system including an interface configured to receive preference data related to the user. The system further includes a physician recommendation module being applied to the preference data and corresponding physician data. The physician recommendation module can track the preference data received by the interface, compare the preference data to the corresponding physician data, and recommend a list of physicians to the user when the physician data is above a threshold value. A display coupled to the recommendation module and configured to display the list of physicians to the user.

Classes IPC  ?

• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G16H 10/20 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des essais ou des questionnaires cliniques électroniques
• G06N 20/00 - Apprentissage automatique

Abrégé

A system provides a computer-implemented rendered visualization of a surgeon's path or "roadmap" to a particular target region during a surgical case are disclosed herein. The system includes an approach library in communication with an operating microscope that includes data related to various surgical approach sequences, or "roadmaps" to various target regions. The approach library can be populated by the system and analyzed for variance and trends, as well as provide direct or indirect instruction and guidance through a display member during a surgical case.

Classes IPC  ?

• G06F 3/00 - Dispositions d'entrée pour le transfert de données destinées à être traitées sous une forme maniable par le calculateurDispositions de sortie pour le transfert de données de l'unité de traitement à l'unité de sortie, p. ex. dispositions d'interface

Abrégé

A system provides a computer-implemented rendered visualization of a surgeon's path or "roadmap" to a particular target region during a surgical case are disclosed herein. The system includes an approach library in communication with an operating microscope that includes data related to various surgical approach sequences, or "roadmaps" to various target regions. The approach library can be populated by the system and analyzed for variance and trends, as well as provide direct or indirect instruction and guidance through a display member during a surgical case.

Classes IPC  ?

• G06F 3/00 - Dispositions d'entrée pour le transfert de données destinées à être traitées sous une forme maniable par le calculateurDispositions de sortie pour le transfert de données de l'unité de traitement à l'unité de sortie, p. ex. dispositions d'interface

Abrégé

Various embodiments of a system and associated method for determining a volume of surgical freedom using a plurality of three-dimensional extrema points along a surgical corridor in relation to a structure of interest are disclosed herein.

Classes IPC  ?

• A61G 13/00 - Tables d'opérationLeurs accessoires
• G09B 23/00 - Modèles à usage scientifique, médical ou mathématique, p. ex. dispositif en vraie grandeur pour la démonstration

Abrégé

Various embodiments of an expandable interbody cage device configured to reduce subsidence into an endplate of a vertebral body by including a plurality of arms that engage the cortical tissue of the vertebral body. The plurality of arms increase the surface area and improve distribution of force, especially around stronger parts of the endplate such as the cortical bone at the rim of the endplate. The expandable interbody cage device maintains a low or slim profile while in a "closed" configuration during insertion between vertebrae and is further operable to laterally expand into an "open" configuration that increases the surface area of the expandable interbody cage device after insertion to securely engage the expandable interbody cage device between the vertebra. The expandable interbody cage device further includes one or more ports and/or cavities in which bone graft material can be disposed within.

Classes IPC  ?

• A61F 2/44 - Articulations pour l'épine dorsale, p. ex. vertèbres, disques intervertébraux

Abrégé

In accordance with some embodiments of the disclosed subject matter, systems, methods, and media for automatically transforming a digital image into a simulated pathology image are provided. In some embodiments, the method comprises: receiving a content image from an endomicroscopy device; receiving, from a hidden layer of a convolutional neural network (CNN) trained to recognize a multitude of classes of common objects, features indicative of content of the content image; receiving, providing a style reference image to the CNN; receiving, from another hidden layer of the CNN, features indicative of a style of the style reference image; receiving, from the hidden layers of the CNN, features indicative of content and style of a target image; generating a loss value based on the features of the content image, the style reference image, and the target image; minimizing the loss value; and displaying the target image with the minimized loss.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
• A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
• A61B 1/313 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour l'introduction dans des incisions chirurgicales, p. ex. laparoscopes
• A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
• G06N 3/045 - Combinaisons de réseaux

Abrégé

A system and method for identifying over sedation risk factors and generating appropriate alerts for healthcare professionals as a result of an algorithm triggered based whether a calculated over sedation risk score/level for the patient crosses a predefined threshold, and determine whether the patient score is at a low, moderate, or high risk for over sedation. If the patient is at a moderate or high risk, an alert may be triggered and displayed to the healthcare professional, along with data associated with the alert in a synchronized timeline displayed on a user interface.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
• G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients

Abrégé

A toothbrush for use by an operator and capable of being connected to a suction device and a syringe. The toothbrush includes a head, a handle, and a suction assembly. The head includes a plurality of bristles and an irrigation port configured to be in fluid communication with the syringe. The handle is coupled to the head and includes a user interface and a controller configured to actuate at least one of rotation, oscillation, and vibration of the plurality of bristles in response to feedback from the operator through the user interface. The suction assembly is coupled to one of the head and the handle and configured to be coupled to the suction device. The suction assembly includes a suction tip that is moveable relative to the head.

Classes IPC  ?

• A61C 17/02 - Dispositifs de rinçage ou insufflateurs d'air, p. ex. utilisant des jets de fluide
• A46B 9/04 - Position ou disposition des soies par rapport à la surface de la monture, p. ex. inclinées, en rangées, en groupes pour les brosses à dents
• A46B 11/06 - Brosses à réservoir ou autre système permettant l'application de produits, p. ex. peintures, pâtes, eau reliées à un tuyau d'alimentation
• A46B 13/02 - Brosses à monture commandée à entraînement mécanique
• A61C 17/36 - Dispositifs à entraînement mécanique pour nettoyer ou pour polir avec des brosses, des éponges, des cupules ou analogues ayant un mouvement alternatif ou oscillant entraînées par un moteur électrique avec des moyens de rinçage

Abrégé

Described herein are methods, systems and compositions for the diagnosis, prognosis and treatment of dementia and Alzheimer's disease. Also described are methods, systems and compositions to distinguish between Alzheimer's disease and Parkinson's disease. In various embodiments levels of PACAP and/or SIRT3 are analyzed for the diagnosis, prognosis and treatment of dementia and Alzheimer's disease.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• A61K 38/22 - Hormones
• A61K 38/46 - Hydrolases (3)
• A61K 38/50 - Hydrolases (3) agissant sur des liaisons carbone-azote autres que des liaisons peptidiques (3.5), p. ex. asparaginase

Abrégé

A device used for stabilizing the pelvis of a patient is provided. The device can include a first strap, a second strap, a fastening mechanism, a first supporting member, a second supporting member, and a first opening. The first strap can be configured to substantially surround the patient at a first location. The second strap can be configured to substantially surround the patient at a second location below the first strap. The first supporting member and second supporting member are coupled between the first strap and the second strap and can be configured to be positioned adjacent a first side and a second, opposite side, respectively, of the patient adjacent the anterior superior iliac spine. The first opening can be defined between the first strap, the second strap, the first supporting member, and the fastening mechanism to permit access to one of the femoral artery and the femoral vein.

Classes IPC  ?

• A61F 5/05 - Dispositifs pour étirer ou réduire les membres fracturésDispositifs pour tractionÉclisses pour l'immobilisation

Abrégé

Various embodiments of a system and associated method for whole-blade acquisition and phase correction for fast and robust MR imaging are disclosed herein. In particular, the system enables sampling of odd and even k-space echoes in the same k-space as well as a whole-blade phase correction strategy to achieve improved image quality at an accelerated imaging rate.

Classes IPC  ?

• G01R 33/48 - Systèmes d'imagerie RMN
• G01R 33/561 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne par réduction du temps de balayage, c.-à-d. systèmes d'acquisition rapide, p. ex. utilisant des séquences d'impulsions écho-planar
• G01R 33/565 - Correction de distorsions d'image, p. ex. dues à des inhomogénéités de champ magnétique
• G01R 33/563 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne de matériaux en mouvement, p. ex. angiographie à écoulement contrasté
• G01R 33/14 - Mesure ou tracé par points des courbes d'hystérésis

Abrégé

Various embodiments of a dural elevating and cutting apparatus and methods of use are disclosed herein.

Classes IPC  ?

• A61B 17/3211 - Scalpels chirurgicaux ou bistourisLeurs accessoires
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

Various embodiments for an airway isolation apparatus having a wire frame that is operable for deploying an isolation drape over a subject's head to protect healthcare and other workers from contagious or otherwise harmful agents are disclosed herein. The drape frame may include a frame base. A frame channel may extend from the frame base and a frame wire may extend through the frame channel. A frame opening may be defined by the frame base and the frame channel of the drape frame. A drape may be disposed in the frame opening. Accordingly, the drape frame may be deployed in place over the chest and head of a subject. The drape may cover the subject's head to isolate the mouth and nose of the subject preparatory to accessing these airways for intubation or other procedure.

Classes IPC  ?

• A61B 46/00 - Draps de chirurgie
• A61B 46/20 - Draps de chirurgie spécialement adaptés aux patients
• A61B 90/40 - Appareils fixés au patient, ou à proximité de celui-ci, spécialement adaptés pour fournir un environnement chirurgical aseptique
• A61G 10/04 - Tentes à oxygène
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
• A61G 10/00 - Locaux de traitement à usage médical

Abrégé

Various embodiments of a hydrophilic catheter introduction system for improved insertion of a shunt catheter are disclosed herein. The catheter introduction system includes an introducer sheath defining an inner surface that includes a hydrophilic coating to aid in passage of a catheter through the introducer sheath. Evaluation of the catheter introduction system with respect to other catheter introduction systems resulted in a significant decrease in average catheter threading time.

Classes IPC  ?

• A61M 25/02 - Dispositifs de maintien en position, p. ex. sur le corps

Abrégé

Various exemplary embodiments relate to an anonymous database system. The system includes a plurality of biometric nodes in communication with one another. Each of the plurality of biometric nodes includes a biometric input that receives biometric data from a user. The system also includes at least one central database in communication with the plurality of biometric nodes; and a plurality of institution databases in communication with the plurality of biometric nodes. A first node of the plurality of biometric nodes is configured to receive a message from a second node of the plurality of biometric nodes, the message requesting authorization of data access by the second node. Various embodiments relate to a method for performing an action requiring multiple levels of authentication using an anonymous database system.

Classes IPC  ?

• G06F 21/32 - Authentification de l’utilisateur par données biométriques, p. ex. empreintes digitales, balayages de l’iris ou empreintes vocales
• H04L 9/40 - Protocoles réseaux de sécurité
• G06F 16/951 - IndexationTechniques d’exploration du Web
• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès