CENTRE FOR EYE AND VISION RESEARCH LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
Inventeur(s)
Huang, Chien-Ling
Yip, Shea Ping
Wong, Ka-Hing
Wong, Nonthaphat
Sun, Jiahong
Jiang, Zhiwei
Abrégé
A method for differentiating induced pluripotent stem cells (iPSCs) into retinal ganglion cells (RGCs) involves deleting a sequence encoding LNC000093 long non-coding RNA from the iPSC genome, culturing the modified iPSCs to generate colonies, and dissociating these colonies to form embryoid bodies. The embryoid bodies are transferred to a first plate to induce neural rosette formation. The neural rosettes are detached and cultured in suspension to develop into neurospheres, which are subsequently transferred to a second plate to promote differentiation into RGCs.
This application relates to an automated data management system and a corresponding method. The system comprises: a data collection module for gathering raw job position data from public resources; a data preprocessing module for preprocessing the collected raw job position data to remove irrelevant information and/or symbols; a data identification module for identifying text related to job skill requirements from the pre-processed data and identifying keywords related to the job skills; a semantic analysis module for semantically analysing the identified keywords related to the job skills and forming a skill classification scheme; a data storage module for establishing a skill database based on the skill classification scheme and storing the skill classification scheme. The system automates the analysis of job postings to identify the most in-demand skills in the current market. Through big data analysis, this invention accurately assesses the demand for various skills, providing valuable data support for job seekers and companies.
A personal cooling enclosing material comprises a garment body; an air cooling system provided on an outside surface of the garment body, wherein the air cooling system further comprises a receptacle and a coolant contained in the receptacle; and an air circulation system provided on an inside surface of the garment body for drawing original air from an internal space inside the garment body for cooling. The air circulation system is separated from the air cooling system to avoid direct contact of the original air with the coolant of the air cooling system. The air cooling system is in thermal communication with the air circulation system.
A41D 13/005 - Vêtements protecteurs de travail ou de sport, p. ex. blouses de chirurgien ou vêtements protégeant des coups ou des chocs avec des conditions d'environnement interne qui sont commandées avec une température commandée
A generator module comprises a stator, a rotator and a mechanical switch. The stator comprises a first group of patterned conductive coatings, a second group of patterned conductive coatings, a first group of dielectric sectors and a second group of dielectric sectors. The rotator comprises a third group of patterned conductive coatings and a third group of dielectric sectors. The first group of patterned conductive coatings electrically connects to a first electrical terminal. The second group of patterned conductive coatings electrically connects to a second electrical terminal. The third group of patterned conductive coatings electrically connects to a third electrical terminal. The mechanical switch allows the third electrical terminal to be selectively connectable to one of the first electrical terminal and the second electrical terminal.
A method for controlling noise for a human subject comprise receiving an acoustic signal by the human subject through a headphone, the acoustic signal comprising a noise signal, generating a cancellation signal based on a hearing target curve that is related to acoustic magnitude and frequency, and applying the cancellation signal to the acoustic signal such that the noise signal is attenuated.
G10K 11/178 - Procédés ou dispositifs de protection contre le bruit ou les autres ondes acoustiques ou pour amortir ceux-ci, en général utilisant des effets d'interférenceMasquage du son par régénération électro-acoustique en opposition de phase des ondes acoustiques originales
A transistor comprising: a source electrode; a drain electrode; a channel comprising an organic semiconductor between the source electrode and the drain electrode; a plurality of gate electrodes; and an electrolyte, wherein the electrolyte contacts the gate electrodes and the channel, and wherein at least one gate electrode comprises an oxidoreductase and at least one gate electrode does not comprise an oxidoreductase, and methods for detecting and/or determining the concentration of an analyte in a sample using the transistor comprising: (i) applying a voltage to the at least one gate electrode which does not comprise an oxidoreductase; (ii) contacting the test sample in the transistor; (iii) applying the voltage used in (i) to the at least one gate electrode which comprises an oxidoreductase, (iv) removing the voltage from the at least one gate electrode which does not comprise an oxidoreductase; wherein (iii) and (iv) occur simultaneously.
A hoisting posture control system and method, applicable to the technical field of modular construction. According to the hoisting posture control system, controllers corresponding to functional modules are called on the basis of data detected by sensors, to drive posture control of a hoisted object, thereby assisting a tower crane operator in making work decisions, so that the operator does not need to take risks to get close to a module to be installed hoisted in the air, ensuring the safety of workers and the accuracy and reliability of module installation. Thus, the labor cost in modular construction work can be reduced, and the assembly quality and efficiency of modules are improved.
B66C 13/08 - Dispositifs auxiliaires pour commander les mouvements des charges suspendues ou pour empêcher le câble de prendre du mou pour déposer les charges selon un orientement ou dans une position donnés
B66C 13/06 - Dispositifs auxiliaires pour commander les mouvements des charges suspendues ou pour empêcher le câble de prendre du mou pour limiter ou empêcher le balancement longitudinal ou transversal des charges
B66C 13/48 - Commande automatique de l'entraînement des grues pour produire un cycle de travail unique ou répétéCommande par programmation
B66C 13/16 - Utilisation de dispositifs indicateurs de positionnement ou de pesée
B66C 1/12 - Élingues comportant chaînes, fils métalliques, cordes ou bandesFilets
8.
HOISTING POSITION AND POSTURE ADJUSTMENT SYSTEM AND HOISTING APPARATUS
A hoisting position and posture adjustment system and a hoisting apparatus. The hoisting apparatus comprises the hoisting position and posture adjustment system, wherein the hoisting position and posture adjustment system comprises a posture adjustment device (20), a hoisting frame (11), a horizontal-displacement adjustment device (13) and a lifting spreader (12) which are sequentially arranged in a vertical direction, the lifting spreader (12) being connected to the hoisting frame (11) or the horizontal-displacement adjustment device (13) and configured to connect to a hoisted object (300); the horizontal-displacement adjustment device (13) is connected to the hoisting frame (11) and is configured to adjust the horizontal position of the hoisted object (300); and the posture adjustment device (20) is connected to the hoisting frame (11) and is configured to adjust the posture of the hoisted object (300), so as to keep the hoisted object (300) in a horizontal posture. By means of the cooperation of the horizontal-displacement adjustment device and the posture adjustment device, the hoisting position and posture adjustment system of the present application can automatically fine-tune the position and posture of a hoisted object, such that the amount of manual participation can be significantly reduced, thereby facilitating a reduction in labor costs and safety risks; moreover, the hoisted object can be accurately placed at a target position, thereby reducing the dependence on workers.
B66C 13/08 - Dispositifs auxiliaires pour commander les mouvements des charges suspendues ou pour empêcher le câble de prendre du mou pour déposer les charges selon un orientement ou dans une position donnés
B66C 1/12 - Élingues comportant chaînes, fils métalliques, cordes ou bandesFilets
9.
A HIGH FREQUENCY, HIGH RESOLUTION 2D PHASED ARRAY ULTRASONIC TRANSDUCER
A 2D phased array ultrasound device possessing ultrahigh spatial resolutions (<90 μm) and high centre frequency (25 MHz) including: a 2D array of piezo crystal elements formed from the kerfing of a single crystal; a series of conductive electrodes formed on opposed sides of the piezo crystal elements; a series of front matching layers; and a backing unit comprising backing filler material and a series of flexible circuit layers sandwich together to interconnect the back surface electrodes of the piezo crystal elements.
B06B 1/06 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique fonctionnant par effet piézo-électrique ou par électrostriction
G10K 11/30 - Procédés ou dispositifs pour transmettre, conduire ou diriger le son pour focaliser ou pour diriger le son, p. ex. balayage utilisant la réfraction, p. ex. lentilles acoustiques
H10N 30/063 - Formation d’interconnexions, p. ex. d’électrodes de connexion de parties piézo-électriques ou électrostrictives multicouches
H10N 30/088 - Mise en forme ou usinage de corps piézo-électriques ou électrostrictifs par usinage par coupe ou découpage en dés
H10N 30/20 - Dispositifs piézo-électriques ou électrostrictifs à entrée électrique et sortie mécanique, p. ex. fonctionnant comme actionneurs ou comme vibrateurs
H10N 30/87 - Électrodes ou interconnexions, p. ex. connexions électriques ou bornes
H10N 39/00 - Dispositifs intégrés, ou ensembles de plusieurs dispositifs, comportant au moins un élément piézo-électrique, électrostrictif ou magnétostrictif couvert par les groupes
10.
Feature Selection Method and System Based on Fuzzy Label Relaxation
The present disclosure provides a feature selection method based on fuzzy label relaxation, which comprises the following steps: (a) acquiring sample data, and performing feature extraction on the sample data to obtain a feature data matrix; (b) learning a fuzzy membership to obtain a fuzzy membership matrix; (c) performing soft relaxation on a label matrix with the fuzzy membership matrix, and constraining a feature selection matrix to be row sparse; and (d) based on the steps (b) and (c), obtaining an objective function of the feature selection based on label fuzzy relaxation, and solving the objective function. In addition, the present disclosure further provides a feature selection system based on label fuzzy relaxation.
Disclosed in the present application is an energy management method for solar freezer trucks, the solar freezer truck includes a photo-voltaic (PV) module, a first battery, a freezer compressor, an engine generator, and an external power adapter connected by an energy management unit, and the energy management method includes obtaining an output power of the PV module; and switching, by the energy management unit, power paths to the freezer compressor according to the output power of the PV module.
A ball sports training method and a ball sports training system. The method comprises: during the process of a training object engaging in ball sports, acquiring a plurality of sports scene images collected by means of an image collection apparatus, and a collection time of each sports scene image; on the basis of the plurality of sports scene images and the collection time of each sports scene image, determining hitting response information of the training object, wherein the hitting response information comprises at least one of hitting implementation information, related-hitting-position information, hitting response time information and hitting speed information; and on the basis of the hitting response information, determining training assessment information for the training object, wherein the training assessment information comprises assessment information about the sports performance of the training object and/or assessment information about the physical health status of the training object. Therefore, the objectivity, accuracy, high efficiency and professionalism of ball sports training are improved, and the labor costs are reduced; and when the solution is applied to rehabilitation training, the effect of rehabilitation training can be significantly improved.
A knee mounting device for providing TENS treatment is disclosed. The knee mounting device is coupled to a patient's knee to locate and stimulate ST-36 acupoint transcutaneously for treating or relieving osteoarthritic pain. The knee mounting device includes a lower assembly mountable onto a leg portion under a kneecap, an upper assembly mountable on a thigh, and a sleeve adapted to connect the upper and lower assemblies. The lower assembly contacts arranged for contacting the ST-36 acupoint, and thermal pad arranged for applying thermal treatment to an area proximate to the ST-36 acupoint. The upper assembly includes a pulse width modulation (PWM) generator configured to generate a pulse stimulation signal and couple the pulse stimulation signal to the contacts for stimulating the ST-36 acupoint. The sleeve is provided with a kneecap opening located to enwrap the patient's knee as anchor and place the contacts on top of the ST-36 acupoint.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
14.
ELECTROMAGNETIC VARIABLE-DAMPING LOCK-UP TYPE LONG-PERIOD VIBRATION CONTROL DEVICE
Provided in the present application is an electromagnetic variable-damping lock-up type long-period vibration control device, comprising a housing, a rotating shaft, a pendulum mass, a braking assembly, a data acquisition element, an electromagnetic variable-damping module and a control module; the rotating shaft is rotationally connected to the housing; the pendulum mass is fixedly connected to the rotating shaft; the braking assembly is used for locking the rotating shaft; the data acquisition element is connected to the rotating shaft; the electromagnetic variable-damping module is connected to the rotating shaft; the control module is installed on the housing; the control module comprises a data processing unit and a controller, the data processing unit being electrically connected to the data acquisition element and being used for obtaining the angular velocity of the pendulum mass, and the controller being separately and electrically connected to the data processing unit, the braking assembly and the electromagnetic variable-damping module. In the present application, the electromagnetic variable-damping module adjusts the damping magnitude of the rotating shaft by means of changing the electromagnetic intensity, and the controller sets a lock-up duration on the basis of control algorithms so as to prolong the period of the device, thereby achieving better control over long-period and even ultra-long-period vibration.
F16F 15/03 - Suppression des vibrations dans les systèmes non rotatifs, p. ex. dans des systèmes alternatifsSuppression des vibrations dans les systèmes rotatifs par l'utilisation d'organes ne se déplaçant pas avec le système rotatif utilisant des moyens électromagnétiques
Disclosed in the present application is an energy management method for solar freezer trucks, the solar freezer truck includes a photo-voltaic (PV) module, a first battery, a freezer compressor, an engine generator, and an external power adapter connected by an energy management unit, and the energy management method includes obtaining an output power of the PV module; and switching, by the energy management unit, power paths to the freezer compressor according to the output power of the PV module.
H02J 7/35 - Fonctionnement en parallèle, dans des réseaux, de batteries avec d'autres sources à courant continu, p. ex. batterie tampon avec des cellules sensibles à la lumière
B60H 1/00 - Dispositifs de chauffage, de refroidissement ou de ventilation
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
H02J 7/14 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries pour la charge de batteries par des générateurs dynamo-électriques entraînés à vitesse variable, p. ex. sur véhicule
H02J 7/34 - Fonctionnement en parallèle, dans des réseaux, de batteries avec d'autres sources à courant continu, p. ex. batterie tampon
16.
ARTIFICIAL REEF DEVICE HAVING BIONIC CORAL TEXTURE STRUCTURE AND REEF MODULE MANUFACTURING METHOD
The present application discloses an artificial reef device having a bionic coral texture structure and a reef module manufacturing method. The artificial reef device having the bionic coral texture structure comprises a main body (10) and a coral stopper module (20). The main body (10) is provided with first connecting structures (11), and the coral stopper module (20) is provided with a second connecting structure (21). The artificial reef device provided by the present application can be easily assembled underwater to form hollow structures of different sizes, providing habitat for various organisms. Additionally, the main body (10) and the coral stopper module (20) both have bionic coral texture structures, matching the natural environment of coral reefs, and conducive to the attachment and growth of marine organisms. The coral stopper module (20) is designed to facilitate coral inoculation in a laboratory, and can be connected to the main body (10) after inoculation. In addition, the artificial reef device is further provided with a biological filtering module (40) for placing oysters to optimize water quality by utilizing the filtering feeding characteristic of the oysters.
An energy management method and system, a computer device, and a readable storage medium. The energy management method comprises obtaining a first current output power and a previous output power of a first energy supply device; obtaining a current power change rate of the first energy supply device on the basis of the first current output power and the previous output power; obtaining a first reference power of the first energy supply device on the basis of the first current output power, the previous output power and the current power change rate; obtaining a second current output power of a second energy supply device; and obtaining a second reference power of the second energy supply device on the basis of the first current output power, the second current output power and the first reference power; obtaining a current flow velocity of a first gas, a current flow velocity of a second gas, and a current furnace temperature; and obtaining a reference flow velocity of the first gas and a reference furnace temperature on the basis of the current flow velocity of the first gas, the current flow velocity of the second gas, and the current furnace temperature.
A method of treating an object contaminated with or suspected of being contaminated with one or more microorganisms, the method comprising contacting the object with a compound such that the compound kills or inhibits the growth of at least a portion of the one or more microorganisms, wherein the compound has Formula 1:
A method of treating an object contaminated with or suspected of being contaminated with one or more microorganisms, the method comprising contacting the object with a compound such that the compound kills or inhibits the growth of at least a portion of the one or more microorganisms, wherein the compound has Formula 1:
or a pharmaceutically acceptable salt thereof, wherein:
R1 is C4-C20 alkyl or C4-C20 alkene; and
R2 is hydrogen, C1-C4 alkyl, or a side chain of a naturally occurring amino acid.
A01N 37/44 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou un de leurs dérivés, et un atome d'azote lié au même squelette carboné par une liaison simple ou double, cet atome d'azote ne faisant pas partie d'un dérivé ou d'un thio-analogue d'un groupe carboxylique, p. ex. acides aminocarboxyliques
A01N 47/30 - Dérivés contenant le groupe N—CO—N—aryle ou N—CS—N—aryle
A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
Disclosed are an energy management method, system, computer device and readable storage medium. The method includes: obtaining a first current output power and a previous output power of a first energy supplier; obtaining a current power change rate of the first energy supplier according to the first current output power and the previous output power; obtaining a first reference power of the first energy supplier according to the first current output power, the previous output power and the current power change rate; obtaining a second current output power of a second energy supplier; obtaining a second reference power of the second energy supplier according to the first current output power, the second current output power and the first reference power; obtaining current flow rates of first and second gas and a current furnace temperature; and obtaining a reference flow rate of the first gas and a reference furnace temperature.
B60L 58/40 - Procédés ou agencements de circuits pour surveiller ou commander des batteries ou des piles à combustible, spécialement adaptés pour des véhicules électriques pour la commande d'une combinaison de batteries et de piles à combustible
B60L 1/12 - Méthodes ou dispositifs de commande ou de régulation
B60L 50/40 - Propulsion électrique par source d'énergie intérieure au véhicule utilisant de la puissance de propulsion fournie par des condensateurs
B60L 50/75 - Propulsion électrique par source d'énergie intérieure au véhicule utilisant de la puissance de propulsion fournie par des batteries ou des piles à combustible utilisant de la puissance de propulsion fournie à la fois par des piles à combustible et des batteries
B60L 58/12 - Procédés ou agencements de circuits pour surveiller ou commander des batteries ou des piles à combustible, spécialement adaptés pour des véhicules électriques pour la surveillance et la commande des batteries en fonction de l'état de charge [SoC]
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
H02J 7/34 - Fonctionnement en parallèle, dans des réseaux, de batteries avec d'autres sources à courant continu, p. ex. batterie tampon
20.
ULTRASONIC TRANSDUCER AND METHOD FOR PREPARING THE SAME
The present application provides an ultrasonic transducer and a method for preparing the same. The ultrasonic transducer includes a substrate layer, a piezoelectric layer, and an acoustic matching layer laminated in sequence along the thickness direction; the piezoelectric layer includes a substrate, the substrate includes a wiring area and a plurality of piezoelectric array elements distributed in a matrix along the row direction and the column direction, and two adjacent piezoelectric array elements are bonded by an insulating adhesive, and the upper and lower surfaces of the piezoelectric array elements and the insulating adhesive are formed by a vacuum-plated electrode layer to form row and column strip electrodes, which can be formed by cutting and photolithography. The end of the first electrode layer is electrically connected to the first conductive element; the end of the second electrode layer is electrically connected to the second conductive element.
B06B 1/06 - Procédés ou appareils pour produire des vibrations mécaniques de fréquence infrasonore, sonore ou ultrasonore utilisant l'énergie électrique fonctionnant par effet piézo-électrique ou par électrostriction
G01N 29/06 - Visualisation de l'intérieur, p. ex. microscopie acoustique
H10N 30/87 - Électrodes ou interconnexions, p. ex. connexions électriques ou bornes
21.
METHOD AND COMPOSITION FOR REDUCING MYOPIA PROGRESSION
A method for reducing myopia progression. In particular, the method includes administering to a subject a compound represented by the following formula or a composition comprising an effective amount of the same:
A method for reducing myopia progression. In particular, the method includes administering to a subject a compound represented by the following formula or a composition comprising an effective amount of the same:
A method for reducing myopia progression. In particular, the method includes administering to a subject a compound represented by the following formula or a composition comprising an effective amount of the same:
or a pharmaceutically accept salt thereof, in which the compound can target and inhibit catechol-O-methyltransferase, up-regulate retinal dopamine expression and change the choroidal thickness of a uvea of the subject, where an increase in choroidal thickness indicates a reduction in myopia progression.
A method for reducing myopia progression. In particular, the method includes administering to a subject a compound represented by the following formula or a composition comprising an effective amount of the same formula (I) or a pharmaceutically accept salt thereof, in which the compound can target and inhibit catechol-O-methyltransferase, up-regulate retinal dopamine expression and change the choroidal thickness of a uvea of the subject, where an increase in choroidal thickness indicates a reduction in myopia progression.
CENTRE FOR EYE AND VISION RESEARCH LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
Inventeur(s)
Zhao, Qian
Zhao, Qi
Abrégé
The disclosure provides a combination of one or more hydrolases and one or more anti-microorganism drugs, and a pharmaceutical composition or a kit comprising the combination. The disclosure also provides a method for treating a microorganism infection by using a therapeutically effective amount of the combination, pharmaceutical composition or kit. The combination of this disclosure is safer, and more economical, and can re-sensitize a drug against lots of bacteria at less dosage in clinical and avoid antimicrobial resistance to extend the lifespan of the drug.
A61K 38/47 - Hydrolases (3) agissant sur des composés glycosyliques (3.2), p. ex. cellulases, lactases
A61K 31/4439 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. oméprazole
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 31/53 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec trois azote comme seuls hétéro-atomes d'un cycle, p. ex. chlorazanil, mélamine
A61K 31/546 - Composés contenant des systèmes cycliques thia-5 aza-1 bicyclo [4.2.0] octane, c.-à-d. composés contenant un système cyclique de formule , p. ex. céphalosporines, céfaclor, céphalexine contenant d'autres hétérocycles, p. ex. céphalotine
A61K 31/7135 - Composés contenant des métaux lourds
CENTRE FOR EYE AND VISION RESEARCH LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
Inventeur(s)
Zhao, Qian
Zhang, Qi
Abrégé
Provided herein are combination of one or more hydrolases and one or more anti-microorganism drugs, and a pharmaceutical composition or a kit comprising the combination. A method for treating a microorganism infection by using a therapeutically effective amount of the combination, pharmaceutical composition or kit is also provided. The combination is safer, and more economical, and can re-sensitize a drug against lots of bacteria at less dosage in clinical and avoid antimicrobial resistance to extend the lifespan of the drug.
A prosthetic limb control method and a system. The prosthetic limb control method comprises: acquiring sensory feedback information and generating a stimulation signal on the basis of the sensory feedback information (102), the sensory feedback information referring to state information of a prosthetic limb being in a first state of contact after being in contact with an external object, the stimulation signal being used for stimulating stress tissue of an amputee, and the stress tissue comprising muscle tissue or nerve tissue corresponding to the prosthetic limb; acquiring stress information generated after the stress tissue receives the stimulation signal (103); and generating a control signal on the basis of the stress information, the control signal being used for dynamically controlling the prosthetic limb to switch from the first state of contact with the external object into a second state of contact (104). The method coordinately corrects the state of contact of prosthetic limbs with external objects on the basis of sensory feedback information, thereby improving the accuracy of control, flexibility and coordination for the prosthetic limbs, enabling the prosthetic limbs to achieve optimal adaptability and thus achieving the purpose of autonomy of amputees.
A method for ultrasound stimulation of spinal cord, the method comprising at least two stimulation cycles, each comprising the steps of: a) obtaining a first real-time spinal cord using a first set of ultrasound transducers; b) selecting a pre-determined stimulation area of the spinal cord from the first real-time spinal cord; c) calculating the position and orientation of the selected stimulation area relative to a second set of ultrasound transducers; and d) stimulating the selected stimulation area of the spinal cord at the calculated relative position and orientation using the second set of ultrasound transducers.
A61B 8/00 - Diagnostic utilisant des ondes ultrasonores, sonores ou infrasonores
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 35/12 - Substances provenant de mammifèresCompositions comprenant des tissus ou des cellules non spécifiésCompositions comprenant des cellules souches non embryonnairesCellules génétiquement modifiées
27.
LONG-TERM PRECISE ULTRASOUND NEUROMODULATION VIA STABLE HOLLOW SILICA NANOPARTICLES
An ultrasound neuromodulation actuator including a stable hollow silica nanoparticle(HSN) structure, in particular, a PEGylated HSN(pHSN) particle, and a method for preparing the same. Provided are methods for enhancing ultrasound stimulation and treating neurological disorders of a subject including applying the pHSN particles to a brain region of the subject followed by ultrasound stimulation.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
28.
INTEGRATED SYSTEM FOR MULTIPLE CULTIVATIONS OF A BIOLOGICAL AGENT AND METHODS OF USE THEREOF
The present invention provides an integrated system built on a microfluidics with multiple layers including a cell culture surface and different chambers configured to allow multiple cultivations of a biological agent, formation of three-dimensional multicellular culture model or biofilm, colonization and re-colonization of the biological agent responsive to a stimuli introduced to the integrated system. Such stimuli include physical, chemical and/or biological substance that may affect proliferation, differentiation, and/or function of the biological agent. The biological agent includes a biofilm-forming microbe such as a ubiquitous biofilm-forming bacterial species or biological cells or tissues of a different origin or species such as eukaryotic cells/tissues. The present integrated system can be used in drug screening, establishment of disease model in vitro or in vivo, evaluation of an anti-microbial efficacy, and studying cell-cell interaction.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12Q 1/18 - Test de l'activité antimicrobienne d'un matériau
LABORATORY FOR ARTIFICIAL INTELLIGENCE IN DESIGN LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
ROYAL COLLEGE OF ART (Royaume‑Uni)
Inventeur(s)
Lee, Ching
Tan, Jeanne
Tan, Jun Jong
Abrégé
A smart textile (100), comprising first conductive yarn (101), thermochromic yarn (102) and polymer optical fibers (103), which are woven in a weft direction, wherein electrodes extending in a warp direction are respectively embroidered at two ends of the first conductive yarn (101); the first conductive yarn (101) is used for producing heat when the electrodes are energized, such that the temperature of the smart textile (100) changes; when the illumination intensity on a surface of the smart textile (100) is greater than a preset value, the thermochromic yarn (102) is configured to present different colors on the basis of the change in the temperature of the smart textile (100); two ends of the polymer optical fibers (103) are respectively gathered to form harnesses and are respectively connected to light source devices (1051, 1052); the polymer optical fibers (103) are configured for presenting the color of light emitted by the light source devices (1051, 1052); and the color of the light emitted by the light source devices (1051, 1052) is determined on the basis of the current temperature of the smart textile (100).
D03D 15/533 - Tissus caractérisés par la matière, la structure ou les propriétés des fibres, des filaments, des filés, des fils ou des autres éléments utilisés en chaîne ou en trame caractérisés par les propriétés des filés ou des fils antistatiquesTissus caractérisés par la matière, la structure ou les propriétés des fibres, des filaments, des filés, des fils ou des autres éléments utilisés en chaîne ou en trame caractérisés par les propriétés des filés ou des fils électriquement conducteurs
30.
INTEGRATED SYSTEM FOR MULTIPLE CULTIVATIONS OF A BIOLOGICAL AGENT AND METHODS OF USE THEREOF
An integrated system built on a microfluidics with multiple layers includes a cell culture surface and different chambers configured to allow multiple cultivations of a biological agent, formation of three-dimensional multicellular culture model or biofilm, colonization and re-colonization of the biological agent responsive to a stimuli introduced to the integrated system. Such stimuli include physical, chemical and/or biological substance that may affect proliferation, differentiation, and/or function of the biological agent. The biological agent includes a biofilm-forming microbe such as a ubiquitous biofilm-forming bacterial species or biological cells or tissues of a different origin or species such as eukaryotic cells/tissues. The integrated system can be used in drug screening, establishment of disease model in vitro or in vivo, evaluation of an anti-microbial efficacy, and studying cell-cell interaction.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
The present invention provides an ultrasound neuromodulation actuator including a stable hollow silica nanoparticle (HSN) structure, in particular, a PEGylated HSN (pHSN) particle, and a method for preparing the same. The present invention also provides methods for enhancing ultrasound stimulation and treating neurological disorders of a subject including applying the pHSN particles to a brain region of the subject followed by ultrasound stimulation.
The present invention provides a compound or derivatives thereof capable of lowering circulating glucose in a subject. The compound is a recombinant placenta-specific protein 9 (Plac9) or derivatives thereof that can enhance glucose uptake by liver cells or hepatocytes in an insulin-independent manner, thereby lowering the circulating glucose. The present invention also provides a composition including an effective amount of the compound or derivatives thereof and a method for treating diseases or conditions associated with or arising from high circulating glucose such as diabetes mellitus.
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A rotary motion generator for helping a patient to relearn walking is disclosed. The knee exoskeleton device includes a rotary shaft, a moveable lever, and a first elastomeric structure. The rotary shaft is switchable between a one-way rotation mode and a two-way rotation mode in a sagittal plane, and locking the joint position by the one-way rotation mode. The moveable lever protrudes from an outer periphery of the rotary shaft perpendicularly for rotating the rotary shaft. The first elastomeric structure is pneumatically controlled for engaging the moveable lever for generating an output torque and producing the relative rotatory movement of a lower arm with respect to an upper arm. The rotary shaft further comprises a pawl, a second elastomeric structure for projecting or retracting the pawl, and a rotation locking mechanism that switches the rotary shaft between the one-way rotation mode and the two-way rotation mode.
Method for preparing a doped metal phosphorus trichalcogenide (dMPT) comprising: (a) contacting a first metal salt, an optional base and a fluorine salt under hydrothermal conditions thereby growing a first metal precursor on a conductive substrate; (b) contacting the first metal precursor with an aqueous solution of a second metal salt thereby forming a doped metal precursor; and (c) contacting the doped metal precursor, phosphorus, and sulfur thereby forming a mixture; and heating the mixture;a dMPT, and a method for producing hydrogen gas using the same.
Method for preparing a doped metal phosphorus trichalcogenide (dMPT) comprising: (a) contacting a first metal salt, an optional base and a fluorine salt under hydrothermal conditions thereby growing a first metal precursor on a conductive substrate; (b) contacting the first metal precursor with an aqueous solution of a second metal salt thereby forming a doped metal precursor; and (c) contacting the doped metal precursor, phosphorus, and sulfur thereby forming a mixture; and heating the mixture; a dMPT, and a method for producing hydrogen gas using the same.
C25B 11/075 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’un seul élément catalytique ou composé catalytique
C01B 25/14 - Composés de phosphore et de soufre, sélénium ou tellure
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
A heat transfer device for applying a varying temperature to a portion of an animate body comprises a liquid conduit. The liquid conduit is liquidly connectable to an external first liquid source to establish a first circulation loop for transporting a first liquid. The liquid conduit is liquidly connectable to an external second liquid source to establish a second circulation loop for transporting a second liquid. The second liquid has a higher temperature than the first liquid. The liquid conduit is operably switchable between the first circulation loop and the second circulation loop for achieving the varying temperature applied to the portion of the animate body.
A method of reducing drug resistance of a cancer to an anticancer drug a subject in need thereof, the method including: administering a therapeutically effective amount of a compound to the subject, wherein the cancer overexpresses peroxiredoxin 1 (PRDX1) and the compound is a triazole linked flavonoid dimer. The anticancer drug can be doxorubicin, daunorubicin, vincristine, cisplatin, paclitaxel, mitoxantrone, and combinations thereof.
C07D 311/30 - Benzo [b] pyrannes non hydrogénés dans le carbocycle avec des atomes d'oxygène ou de soufre liés directement en position 4 avec des cycles aromatiques liés en position 2 ou 3 avec des cycles aromatiques liés uniquement en position 2 non hydrogénés dans l'hétérocycle, p. ex. flavones
LABORATORY FOR ARTIFICIAL INTELLIGENCE IN DESIGN LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
ROYAL COLLEGE OF ART (Royaume‑Uni)
Inventeur(s)
Liu, Rong
Wang, Ping
Mao, Qian
Abrégé
A leg shape intelligent recognition method and apparatus, an electronic device, and a storage medium, relating to the technical fields of human body measurement, garment fitness, and computer application. The method comprises: acquiring a key feature parameter value of a leg object to be identified (S102); and inputting the key feature parameter value into a trained support vector machine classification model to obtain a target leg shape category to which said leg object belongs and a circumference size category under the target leg shape category (S104).
A ring focus spectacle lens (1) for controlling the progression of myopia, and a manufacturing method therefor. The ring focus spectacle lens (1) can provide clear vision for a patient, and also has a plurality of ring-shaped defocusing zones to provide an optical defocusing effect. Since there is no joint between successive concentric rings of different optical powers that are tangent to each other, the ring focus spectacle lens (1) is as aesthetic as a common spectacle lens. In the manufacturing method, three front mold cores (71), a rear mold core (72), and a planar rear mold core are used to manufacture a series of ring focus spectacle lenses (1) having different powers, thereby reducing the number of mold cores and the production cost. In addition, for the requirements of individuals with severe myopia and astigmatism, a semi-finished lens is provided by means of the manufacturing method, which not only greatly reduces the number of mold cores, but also reduces the inventory quantity of desired lenses, thereby reducing costs.
2 complex layer. In one embodiment, said method for manufacturing a perovskite with a modified surface, comprises the steps of: a) Providing a perovskite with a surface to be modified; b) Treating said surface to be modified with DPGABr; and c) Annealing to form said perovskite with a modified surface.
An ankle exoskeleton device for helping a patient to relearn walking by themselves is disclosed. The ankle exoskeleton device includes a leg brace, an insole, and a rotary actuator. The rotary actuator is pneumatically driven to cause rotation of the insole with respect to the leg brace about a central axis. The rotary actuator comprises first and second elastomeric structure, a rotary shaft rotatable about the central axis to generate an output torque for producing a relative rotatory movement of the insole, and a lever. the rotary shaft is adapted to be moved by controlling two opposing fluid pressures inside the rotary actuator. The first elastomeric structure is extendable to push the lever in a clockwise direction, and the second elastomeric structure is extendable to push the lever in an anticlockwise direction, thereby the first and second elastomeric structures are arranged to control the rotary shaft.
BO INNOHEALTH BIOTECHNOLOGY COMPANY LIMITED (Chine)
Inventeur(s)
Chang, Jinhui
Chiou, Jiachi
Abrégé
The present application relates to the technical field of health-care foods and particularly relates to the use of tremella polysaccharides in preparing products for preventing and treating high-fat diet induced anxiety. It is found by researches in the present application that tremella polysaccharides can relieve the weight gaining of mice fed by high-fat diet, reduce the weights of the liver and fat, inhibit microglial cell activation and neuritis in the hippocampus, balance the intestinal flora, and have an excellent improvement effect on preventing and treating anxiety of mice caused by high-fat diet feeding. The present application verifies that tremella polysaccharides have the effect of preventing and treating high-fat diet induced anxiety and thus can be used to prepare products for preventing and treating high-fat diet induced anxiety. Therefore, as a nutritional intervention strategy for high-fat diet induced anxiety disorders, tremella polysaccharides are of great significance for assisting in preventing and relieving high-fat diet induced anxiety disorders.
A61K 31/715 - Polysaccharides, c.-à-d. ayant plus de cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiquesLeurs dérivés, p. ex. éthers, esters
A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon
43.
METHOD AND APPARATUS FOR GENERATING HEAD ULTRASOUND IMAGE, TERMINAL DEVICE, AND STORAGE MEDIUM
Embodiments of the present application are suitable for the technical field of ultrasonics, and provide a method and apparatus for generating a head ultrasound image, a terminal device, and a storage medium. The method comprises: in response to a start instruction, obtaining a head depth image of an individual to be checked, and on the basis of the head depth image, determining a plurality of sites to be checked; on the basis of a head feature value of each site to be checked, determining a first target site from among the plurality of sites to be checked; transmitting an ultrasonic signal to the first target site by means of a signal transmit unit, so as to generate a first head ultrasound image of the individual to be checked. According to the method provided in the embodiments of the present application, the terminal device can assist an ultrasonic operator in quickly and accurately finding a target site, thereby quickly obtaining a high-quality ultrasound image.
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
Provided are novel recombinant fusion proteins comprising asparaginase portion fused with an albumin-binding portion. The long-acting recombinant fusion proteins are able to deplete both asparagine and glutamine upon administration to a subject in need thereof, enabling these proteins to be used in the treatment of disease treatable by asparagine and/or glutamine depletion, such as gastric cancer, and food treatment.
The present invention provides a method for storing digital data in proteins including: providing digital code that has been encoded from the digital data; assigning each of a plurality of amino acid residues with a specific binary sequence composed of at least three bits each selected from "0" or "1", where the plurality of amino acid residues is selected from at least eight different amino acid residues as data-bearing amino acid residues; translating the digital code into an amino acid sequence according to the specific binary sequence assigned to each of the amino acid residues; and synthesizing the one or more proteins each including a plurality of peptide segments, where each of the peptide segments includes no more than 30 amino acid residues and each of the proteins contains 100 to 2, 000 amino acid residues. The present invention also provides a method for retrieving digital data from the proteins.
The present application relates to the prevention and treatment of osteoarticular diseases, in particular osteoarthritis (OA), by inhibition of acetylcholinesterase (AChE). Specifically, this application provides a disease progression-modifying drug for the treatment of osteoarthritis, i.e., an acetylcholinesterase inhibitor, in particular a dimeric acetylcholinesterase inhibitor. The dimer targets both the enzymatic triad and non-enzymatic peripheral sites of acetylcholinesterase, thereby enhancing protection of articular cartilage and subchondral bone.
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
A61K 31/165 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide
A61K 31/439 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle le cycle formant une partie d'un système cyclique ponté, p. ex. quinuclidine
A61K 31/445 - Pipéridines non condensées, p. ex. pipérocaïne
A61K 31/473 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. acridines, phénantridines
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
47.
HEAD SIZE MEASUREMENT METHOD AND APPARATUS, HEAD GRID GENERATION METHOD AND APPARATUS, MEDIUM, AND DEVICE
LABORATORY FOR ARTIFICIAL INTELLIGENCE IN DESIGN LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
ROYAL COLLEGE OF ART (Royaume‑Uni)
Inventeur(s)
Luximon, Yan
Zhang, Jie
Abrégé
The present disclosure relates to the technical field of artificial intelligence, and provides a head size measurement method and a 3D head grid generation method. According to the method, a face local area is determined by means of face feature points, a circular reference object is extracted from the face local area, and a head size of a target object is determined on the basis of the size of the circular reference object, thereby generating a 3D head grid. The accuracy is high.
A bionic finger (10), comprising: skin (100), an elastomer (200), a rigid supporting member (300) and a liquid delivery tube (400), wherein the skin (100) is provided with first liquid output holes (110); the elastomer (200) is wrapped and mounted in the skin (100), the elastomer (200) is provided with second liquid output holes (210), and the rigid supporting member (300) is wrapped and mounted in the skin (100); and a side portion of a first end (401) of the liquid delivery tube (400) is provided with third liquid output holes (410), the third liquid output holes (410), the second liquid output holes (210) and the first liquid output holes (110) are in communication with each other, and a second end (402) of the liquid delivery tube (400) extends to the outside of the skin (100). When the skin (100) of the bionic finger (10) comes into contact with a grabbed object, a liquid can flow from the second end (402) of the liquid delivery tube (400) located outside the skin (100) to the first end (401) of the liquid delivery tube (400) located inside the skin (100), and reaches a position between the skin (100) and the grabbed object sequentially through the third liquid output holes (410), the second liquid output holes (210) and the first liquid output holes (110), such that a friction coefficient between the bionic finger (10) and the grabbed object is changed, and thus a friction force between the bionic finger and the grabbed object is changed, thereby solving the technical problem of being unable to adjust the friction force with the bionic finger. Further provided are a fixture, and a manufacturing method for the bionic finger.
LABORATORY FOR ARTIFICIAL INTELLIGENCE IN DESIGN LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
ROYAL COLLEGE OF ART (Royaume‑Uni)
Inventeur(s)
Wong, Wai Keung Calvin
Chen, Zhewei
Zhang, Rongchen
Abrégé
The present disclosure belongs to the technical fields of computers and defect detection. Provided are a defect detection method and a related device. The method comprises: obtaining an image to be processed; processing said image by means of a feature extraction module in a deep-learning defect detection model, wherein the feature extraction module comprises an intermediate feature layer, the intermediate feature layer comprises a dropout layer, and the dropout layer is configured to randomly drop features which are extracted by means of the intermediate feature layer processing said image, such that a plurality of features subjected to random dropout are obtained after said image is processed by means of the feature extraction module; by means of a detection head in the deep-learning defect detection model, processing the plurality of features subjected to random dropout, so as to obtain a plurality of category prediction results and a plurality of position prediction results of defects in said image; and obtaining category detection results, position detection results, category uncertainties and position uncertainties of the defects in said image according to the plurality of category prediction results and the plurality of position prediction results of the defects. (FIG. 1)
A method for certifying a Science, Technology, Engineering and Mathematics (STEM) industrial product is provided. Exemplarily, the method comprises: evaluating and scoring (831) a STEM literacy level acquirable by using the product to thereby yield a first score for STEM literacy; evaluating and scoring (832) product features findable in the product to thereby yield a second score for product features; evaluating and scoring (833) general abilities learnable after using the product to thereby yield a third score for general abilities; making (842) a final decision on a total score for the product according to the first, second and third scores; and awarding (843) the product with a certification level according to the total score of the product.
A transcranial sonography application device (100), comprising an annular guide rail (12), a first mounting frame (21), a first object-bearing platform (22) and a first detection assembly (3). The annular guide rail (12) is erected on the head of a user, the first mounting frame (21) is slidably connected to the annular guide rail (12) and is configured to drive the first object-bearing platform (22) to rotate around a circumferential direction of the head of the user, and the first detection assembly (3) is disposed on the first object-bearing platform (22) and is configured to scan the outer contour of the head of the user and determine the position of a cranial acoustic window. The transcranial sonography application device (100) can solve the technical problems in the prior art of high positioning difficulty and inaccurate positioning of the cranial acoustic window.
A plate-to-roller imprinting apparatus capable of manufacturing a large-area micro/nano-structure (220) on an optical glass plate (100), and a method for processing the micro/nano-structure (220) on the optical glass plate (100). The plate-to-roller imprinting apparatus comprises a roller module (1) and a workpiece support module (2). The roller module (1) comprises a roller (11); the workpiece support module (2) comprises a workpiece table (21); the workpiece table (21) is arranged below the roller module (1); a core plate (22) is provided on top of the workpiece table (21); the micro/nano-structure (220) is provided on an upper surface of the core plate (22); and a heating device (3) is provided in the workpiece table (21), and the heating device (3) is located below the core plate (22); the optical glass plate (100) is arranged on the upper surface of the core plate (22); and the heating device (3) is used for heating the optical glass plate (100). The roller (11) rolls so that pressure can be applied to the optical glass plate (100), and one of the roller (11) and the workpiece table (21) can move in a reciprocating manner in a direction perpendicular to the central axis of the roller (11).
G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
A method of training a learning network to perform image segmentation includes receiving training data from a trusted source and an alternative source; assigning weights to data in the second corpus; dividing the data into batches with samples from the first and second corpuses; and completing training epochs by, for each batch: generating an output for each sample; determining a loss by comparing the generated output with a ground truth for each sample; defining a discrepancy for each second corpus sample as a difference between the sample loss and the average loss for the first corpus, approximated as the average loss for the first corpus from the preceding epoch modified by a change in the average loss from the preceding to the current epoch; identifying weights for the next batch which minimise the weighted sum of discrepancies and network parameters which minimise the average weighted loss.
A method for certifying a Science, Technology, Engineering and Mathematics (STEM) industrial product is provided. The method comprises: evaluating and scoring a STEM literacy level acquirable by using the product to thereby yield a first score for STEM literacy; evaluating and scoring product features findable in the product to thereby yield a second score for product features; evaluating and scoring general abilities learnable after using the product to thereby yield a third score for general abilities; making a final decision on a total score for the product according to the first, second and third scores; and awarding the product with a certification level according to the total score of the product.
G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
55.
GLUCOREGULATORY COMPOUND, COMPOSITION AND USES THEREOF
The present invention provides an isolated glucoregulatory compound having both insulinotropic and blood glucose lowering activities, a composition and uses thereof for treating diseases associated with insulin deficiency or failure in glucose uptake independent of insulin secretion by pancreatic cells such as hyperglycemia, type 1 diabetes, or type 2 diabetes mellitus in a subject.
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
56.
INTELLIGENT ADAPTIVE WAVEFRONT MEASUREMENT SYSTEM AND METHOD FOR OPTICAL CHARACTERIZATION
The present invention provides an intelligent adaptive wavefront measurement system for optical characterization. The system can obtain optical parameters of a sample to be measured. The system comprises a light source, a shearing generator, and a photoelectric coupling device which are sequentially arranged in the axial direction, wherein the shearing generator comprises a spatial light modulator and a phase difference micro-lens array which are sequentially arranged in the axial direction. In addition, the present invention further provides a corresponding method and a training method in a simulation environment, such that a machine learning-based adaptive technology is used for wavefront modulation of the spatial light modulator.
G01J 9/02 - Mesure du déphasage des rayons lumineuxRecherche du degré de cohérenceMesure de la longueur d'onde des rayons lumineux par des méthodes interférométriques
57.
FONT GENERATION MODEL TRAINING METHOD AND RELATED DEVICE
LABORATORY FOR ARTIFICIAL INTELLIGENCE IN DESIGN LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
ROYAL COLLEGE OF ART (Royaume‑Uni)
Inventeur(s)
Wang, Pan
Zhang, Xun
Wang, Stephen Jia
Lee, Kun Pyo
Abrégé
The present disclosure provides a font generation model training method and a related device. The method comprises: obtaining a sample text image of a reference font, description information of a target font and a target text image of the target font, wherein the sample text image and the target text image comprise the same text; inputting the sample text image of the reference font and the description information of the target font into a font generation model to be trained, so as to obtain a predicted text image of the target font; and according to the predicted text image of the target font and the target text image of the target font, training a generative adversarial network comprising the font generation model and a discrimination network, so as to obtain a trained font generation model.
A wireless charging system for providing multi-frequency and multi-speed charging modes to transfer power wirelessly from a base device to a remote device is disclosed. The wireless charging system includes a split transmitter having a plurality of sub-transmitters; a split receiver having a plurality of sub-receiver; and a switched-capacitor circuitry comprising a plurality of switched-capacitor switches. The plurality of sub-receivers and the plurality of sub-transmitters each comprises co-planar induction coils of non-equal cross-sectional lengths positioned concentrically without an interception. The split transmitter and the switched-capacitor circuitry are controlled by a hybrid pulse width modulation (PWM) control method, and the split receiver is controlled by a model predictive control method.
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
59.
PSYCHOLOGICAL STRESS LEVEL DETECTION METHOD, APPARATUS AND SYSTEM
The present application is applicable to the technical field of data processing, and provides a psychological stress level detection method, apparatus and system. The method comprises: obtaining the number of micro-gestures, i.e., the frequency of micro-gestures, performed by a user within a first preset period; and inputting the frequency of micro-gestures into a stress level detection model to obtain the stress level grade of the user. According to the method provided by the present application, the stress level grade of the user is determined according to the frequency of micro-gestures performed by the user, so that the accuracy of detecting the stress level grade of the user can be improved. Moreover, compared with determining the stress level grade of the user by means of recorded sound data or image data, the method can reduce the risk of leaking user privacy, and has wider application scenarios.
G16H 20/70 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mentales, p. ex. la thérapie psychologique ou le training autogène
60.
MULTIFUNCTIONAL CHARGING CIRCUIT, ELECTRIC DEVICE, AND CHARGING SYSTEM
A multifunctional charging circuit includes: a first inverter circuit connected to a primary side winding of an isolation transformer and configured to convert a received first direct current into a first alternating current, then outputting it to the primary side winding; a first wireless charging coil, with one end connected to a corresponding end of a secondary side winding of the isolation transformer, and designed to receive electrical power wirelessly transmitted by a second wireless charging coil; a first resonance compensation circuit connected to the other end of the first wireless charging coil and the corresponding end of the secondary side winding, and configured to generate a resonance based on the electrical power received by the first wireless charging coil and/or the first alternating current received by the secondary side winding, subsequently outputting a first charging current to the rectifier circuit.
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 7/06 - Régulation du courant ou de la tension de charge utilisant des tubes à décharge ou des dispositifs à semi-conducteurs
61.
Multi-dimensional intelligent garment pressure test dress form apparatus and system, and multi-dimensional intelligent garment pressure test method
A multi-dimensional intelligent garment pressure test dress form apparatus and system, and a multi-dimensional intelligent garment pressure test method. The intelligent garment pressure test dress form apparatus comprises an apparatus main body and a human body model (2), wherein the human body model (2) is circumferentially segmented into a plurality of model units (21) around an axis; and the apparatus main body comprises a plurality of movable members (6) and a control base (1). Each movable member (6) is circumferentially distributed on the control base (1) around the center of a circle, and each movable member (6) is movably arranged in a straight line where a connecting line between the center of the movable member and the center of a circle is located; the model units (21) are respectively mounted on the movable members (6) on a one-to-one basis; and the control base (1) is used for driving the movable members (6) to move together or separately, so that multiple dimensions of the size and shape of the human body module (2) can be adjusted and changed. Therefore, when applied to a garment pressure test, the dress form apparatus can implement an intelligent, dynamic and shape-adjustable garment pressure test which includes a plurality of human body sizes, without frequently changing the human body module (2), thereby realizing economic and effective garment functionality measurement.
The present application relates to the technical field of medicine. Provided is the use of integrin α5β1 as a target in the screening of drugs for preventing and/or treating bone loss. 8-isoprenyl flavone glycoside can replace a ligand fibronectin on cell surface receptor integrin α5β1, thereby achieving the binding of 8-isoprenyl flavone glycoside to the integrin α5β1, and thus improving the osteogenesis ability and the cell adhesion. Therefore, by using integrin α5β1 as a target of a drug for preventing and/or treating bone loss, and by means of the binding of 8-isoprenyl flavone glycoside to integrin α5β1, the activities of ALP, RhoA and Rac1 in bone marrow mesenchymal stem cells can be significantly improved, thereby promoting the osteogenesis and the cell adhesion, promoting the development of drugs for bone loss, and providing a new strategy and routine for the treatment of bone loss diseases.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G16B 15/30 - Ciblage de médicament à l’aide de données structurellesPrévision d’amarrage ou de liaison moléculaire
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
A61P 19/10 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget de l'ostéoporose
63.
Gait event-driven, phase-dependent and multi-modal foot rehabilitation system and use method thereof
A gait event-driven, phase-dependent and multi-modal foot rehabilitation system, and a use method thereof. The system comprises: a pressure sensor module (110) which measures a pressure distribution value of a foot sole in real time; a micro-control module (111) which compares the measured pressure value with a preset threshold value to identify different gait events in a dynamic gait and a pressure balance on the inner and outer sides of the foot sole and to control a corresponding operation in real time; a neuromuscular electrical stimulation module (100) which applies or stops a suprathreshold electrical stimulation delivered to a target muscle of the foot on the basis of the recognized gait event; a combined pneumatic musculo-skeletal module (200) which comprises a pneumatic muscle (305) and deflates or inflates the pneumatic muscle (305) on the basis of the recognized gait event; and a vibratory biofeedback module (109) which, when recognizing an imbalance of pressure between the inner side and the outer side of the foot sole, provides a biofeedback to correct the imbalance of force exerted by the foot sole. The gait events comprises heel striking, heel off and sole off. The system can correct foot drop and foot varus, mitigate muscle compensation and dystrophy, and restore a normal gait.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
An immersive projection system (100) is installed in an immersive room (150).The immersive room (150) comprises a ceiling having an opening and a floor. The immersive projection system (100) comprises an image generator (110) which configured to render images to be displayed, a projection warping system (120) which configured to warp and blend rendered images received from the image generator (110), and a plurality of projectors (155) which configured to project images output from the projection warping system (120) into the immersive room (150). One of the plurality of projectors (155) is configured to project images onto the floor through the opening.
An immersive projection system comprises an image generator configured to render images to be displayed; a projection warping system configured to warp and blend rendered images received from the image generator; an immersive room including ceiling having an opening and floor; and a plurality of projectors configured to project images output from the projection warping system into the immersive room; wherein, one of the plurality of projectors is configured to project images onto the floor through the opening.
A Hybrid Interactive Virtual Environment (HiVE) system and a method of use thereof are provided, said system and method are configured for clinical education and training. Said system comprising: an immersive room, which is 6-sided Cave Automatic Virtual Environment (CAVE) platform and is configured to a fully immersive interactive hybrid classroom; an image generator, which is configured to process input contents and render the input contents in either two dimensional (2D) mode or three dimensional (3D) mode to generate interactive contents for clinical education and training; a projection warping system to perform a process of projection warping and blending to generate a projection warped display image; and a video processing system to process the projection warped display image to generate a frame-synchronized display output; wherein the immersive room comprises a surround sound system to produce audio output to the interactive contents, a motion capture system to produce tracking information of the users inside the immersive room and send the tracking information to the interactive contents, and projectors to project the frame-synchronized display output from the video processing system to generate a 3D interactive image within the immersive room for clinical education and training, such that users in the immersive room may watch and listen to the 3D image and interact with the 3D image and/or with each other for clinical education and training.
An Internet-based infectious disease prevention and control training system and an Internet-based infectious disease prevention and control training method. The system comprises a resource database, an application server, a network medium, and an application program on an intelligent terminal; the resource database comprises a service database and a user information database; the service database comprises texts, audios, images, short videos, and game controls; the application server comprises an access management module, a resource scheduling module, a report generation module, and a network optimization module; the access management module authenticates, on the basis of the user information database, login request information sent by a user; the resource scheduling module schedules the texts, the audios, the images, the short videos, or the game controls in the service database according to an instruction sent by the application program, and presents the texts, the audios, the images, the short videos, or the game controls to the intelligent terminal by means of the network medium; the application program comprises a plurality of themes associated with an infectious disease prevention and control standard file; and each theme is presented in the form of one or more games.
G06Q 10/0631 - Planification, affectation, distribution ou ordonnancement de ressources d’entreprises ou d’organisations
G06Q 10/06 - Ressources, gestion de tâches, des ressources humaines ou de projetsPlanification d’entreprise ou d’organisationModélisation d’entreprise ou d’organisation
Methods for treating or preventing a skeletal sequelae of a coronavirus infection in a subject in need thereof, the method comprising administering a therapeutically effective amount of an endothelin receptor antagonist to the subject, with the proviso that the endothelin receptor antagonist is not co-administered with dapagliflozin or niclosamide. The skeletal sequelae can include one or more of arthralgia, viral arthritis, osteopenia, osteochondral damage, and osteoporosis.
The present application discloses a current collector and a manufacturing method therefor, an electrode sheet, a battery, and an electric device. The current collector comprises a dense carbon nanotube film layer and a metal layer bonded to the surface of the dense carbon nanotube film layer. Compared with a commercial metal foil, the weight of the current collector provided by the present application is only 15%-19% of that of the commercial metal foil, and the thickness of the current collector is 24%-32% of that of the commercial metal foil; moreover, the current collector has similar conductivity and electrochemical stability, and the mechanical strength and flexibility of the current collector are greatly improved. The mass specific energy density and the volume specific energy density of a battery using the current collector are respectively increased by 10.2%-25.7% and 5.1%-11.45%.
This invention provides an all-in-one device for virus diagnosis, especially for a target nucleic acid sequence or target antigens or anitbodies in a single sample, comprising: a sample chamber for holding a cuvette with a UCNP-based assay and said sample; a NIR light source; a sensor for measuring fluorescence emission from a UCNP-based assay comprising a light-to-frequency converter; Optics providing an optical path ensuring only fluorescence emission from said UCNP-based assay reaches said sensor; and a microcontroller; wherein said UCNP-based assay is a system comprising UCNP surface modified with a first oligo probe and AuNP surface modified with a second oligo probe, wherein said first oligo probe and said second oligo probe are independently complimentary to separate segments on said target nucleic acid sequence that are nearby each other; or/and a system comprising ligand-free UCNP with electrostatic attraction to said target protein and AuNR surface modified with antibodies for said target protein.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
C12Q 1/6804 - Analyse d’acides nucléiques utilisant des immunogènes
C12Q 1/6816 - Tests d’hybridation caractérisés par les moyens de détection
A vision improvement module, comprising: a screen (1), an optical path folding lens assembly (2) and a zooming mechanism. The optical path folding lens assembly (2) is disposed on a light-emitting side of the screen (1), and the zooming mechanism is connected to the screen (1) or the optical path folding lens assembly (2). The vision improvement module changes the distance from the screen (1) to the nearest lens according to the degree of myopia of a user, so that the user is able to clearly see the screen (1) with the naked eye. On the basis of foregoing, an imaging position is continuously changed by means of the axial reciprocating motion of the screen (1) within a certain length range, or the optical path folding lens assembly (2) is adjusted by means of the zooming mechanism, so as to continuously change the focal length, thereby adjusting the activity of the ciliary muscles in the eyes, and finally improving myopia.
A computer-implemented method for training a convolutional neural network (CNN) using training data comprising a pair of original and downsampled 4D magnetic resonance imaging (MRI) data is provided. The CNN is used to generate multi-parametric 4D magnetic resonance (MR) images based on multi-parametric 3D MR images in real-time. The method includes receiving a 4D MR image formed by a plurality of fixed images of different frames; converting the plurality of fixed images into a plurality of k-space data by non-uniform fast Fourier transform (NUFFT); applying radial scan to the k-space data to simulate real-time MR image acquisition, and generating a plurality of downsampled fixed images by inverse NUFFT; training a CNN with training data comprising the 4D MR image and the corresponding downsampled 4D MR image; and estimating the multi-parametric 4D MR image in real-time by applying apply the predicted DVF to the multi-parametric 3D MR images.
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
LABORATORY FOR ARTIFICIAL INTELLIGENCE IN DESIGN LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
ROYAL COLLEGE OF ART (Royaume‑Uni)
Inventeur(s)
Lee, Ka Man
Chung, Kwok Tung
Chung, Sui Ying
Abrégé
Provided are a printing defect detection method and apparatus, and a device and a storage medium, which relate to the technical field of computers. The method comprises: acquiring an initial target image of a printed product to be subjected to detection; acquiring a reference image corresponding to said printed product; aligning the initial target image with the reference image in a plurality of modes, so as to respectively obtain a plurality of candidate transformed target images; determining a transformed target image on the basis of the degree of similarity between each of the plurality of candidate transformed target images and the reference image; performing color distribution feature standardization processing on the transformed target image on the basis of the reference image, so as to obtain a standardized transformed target image; and obtaining a final difference result on the basis of the standardized transformed target image and the reference image, so as to detect a printing defect of said printed product according to the final difference result.
A permeable stretchable bioelectronic device with wafer-scale patterning capability including a stretchable and permeable substrate and one or more electronic components disposed on a surface of the substrate, wherein the stretchable and permeable substrate includes a biocompatible elastomeric fiber or a biocompatible hydrogel and the each of the one or more electronic components independently include a metal and a liquid metal and a method of fabrication thereof.
A multi-layered scaffold useful for osteochondral complex defects. The multi-layered scaffold can be prepared by photopolymerizing a multi-layer scaffold precursor including: a first layer disposed on a surface of a second layer, wherein the first layer includes a first tri-block poly(lactide-co-propylene glycol-co-lactide) dimethacrylate; and the second layer includes a second tri-block poly(lactide-co-propylene glycol-co-lactide) dimethacrylate, hydroxyapatite nanoparticles covalently conjugated to one or more hydroxyethyl methacrylate moieties via an optional linker, and a photoinitiator, wherein the nanoparticles comprise hydroxyapatite, tricalcium phosphate, silicon dioxide, bioglass, or a mixture thereof.
A prosthetic hand device mountable on a residual limb of an amputee is provided. The prosthetic hand device includes a myoelectric hand having five mechanical fingers actuatable to provide multiple degrees of freedom of movement, a control assembly including an ultrasound module as a human-machine interface, wherein the ultrasound module is configured to acquire ultrasound images of a region of the residual limb, a transfer learning model having a convolutional neural network architecture for obtaining extracted features from the ultrasound images, and an artificial intelligence model executed by one or more processors and configured to classify the extracted features from the ultrasound images for determining a volitional movement of the amputee in real-time. The volitional movement is transmitted to the myoelectric hand to dynamically and proportionally control the five mechanical fingers based on at least the volitional movement.
A prosthetic hand device mountable on a residual limb of an amputee is provided. The prosthetic hand device includes a myoelectric hand having five mechanical fingers actuatable to provide multiple degrees of freedom of movement, a control assembly including an ultrasound module as a human-machine interface, wherein the ultrasound module is configured to acquire ultrasound images of a region of the residual limb, a transfer learning model having a convolutional neural network architecture for obtaining extracted features from the ultrasound images, and an artificial intelligence model executed by one or more processors and configured to classify the extracted features from the ultrasound images for determining a volitional movement of the amputee in real-time. The volitional movement is transmitted to the myoelectric hand to dynamically and proportionally control the five mechanical fingers based on at least the volitional movement.
G06T 7/246 - Analyse du mouvement utilisant des procédés basés sur les caractéristiques, p. ex. le suivi des coins ou des segments
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes
A method of treating a coronavirus infection in a subject in need thereof, the method including administering a therapeutically effective amount of an endothelin receptor antagonist to the subject, with the proviso that the endothelin receptor antagonist is not co-administered with dapagliflozin or niclosamide.
A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/4025 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil non condensés et contenant d'autres hétérocycles, p. ex. cromakalim
A61K 31/422 - Oxazoles non condensés et contenant d'autres hétérocycles
A61P 31/14 - Antiviraux pour le traitement des virus ARN
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A data processing method and apparatus. The method comprises: a first device acquires first data, and inputs the first data into a trained task model to obtain a processing result output by the task model, wherein the task model comprises a pre-trained model and at least one prompt module, the pre-trained model is divided into a plurality of modules, and every two adjacent modules among the plurality of modules correspond to one of the at least one prompt module; and input data of a first module arranged at a start position among the plurality of modules comprises first data, and input data of any second module arranged behind the first module among the plurality of modules is determined according to a processing result output by a module previous to the second module and a correction factor output by a target prompt module. According to the method, on the basis that the structure of a pre-trained model is not changed, a correction factor is used to better stimulate the pre-trained model to migrate pre-training knowledge so as to perform pixel-level semantic annotation, thereby improving task processing precision.
A method of preparing core-shell nanoparticles, the method comprising: contacting a mixture comprising a first metal oxide, a first encapsulating material comprising an alkali metal or alkaline earth metal, and a second encapsulating material comprising a second metal oxide with hydrogen gas at a temperature higher than the hydrogen reduction temperature of the first metal oxide and lower than the decomposition temperature of the first encapsulating material resulting in the reduction the first metal oxide and the formation of metal nanoparticles that are at least partially encapsulated with a bimetallic oxide comprising the alkali metal or the alkaline earth metal and the second metal oxide thereby forming the core-shell nanoparticles, wherein the Tammann temperature of the first encapsulating material is lower than the hydrogen reduction temperature of the first metal oxide.
B01J 23/76 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe du cuivre ou des métaux du groupe du fer en combinaison avec des métaux, oxydes ou hydroxydes prévus dans les groupes
82.
CURRENT COLLECTOR FOR BATTERY AND METHOD FOR FABRICATING THE SAME
The present disclosure provides an ultrathin and superlight glass-fiber based current collector enabling energy-dense flexible batteries, and a method for fabricating the current collector. This current collector includes a metal-coated glass-fiber fabric having metal-coated glass fibers, and the metal-coated glass fiber includes a surface-modified glass fiber covered by one or two metal layers.
H01M 4/131 - Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p. ex. LiCoOx
H01M 4/74 - Grillage ou matériau tisséMétal déployé
H01M 50/141 - Boîtiers primairesFourreaux ou enveloppes pour protéger contre les dommages causés par des facteurs externes pour protéger contre l’humidité
Provided are an optical fiber sensor and a magnetic field strength measuring apparatus. The optical fiber sensor comprises an optical fiber (2) and a magnetic component (1). At least one optical fiber (2) is provided. The optical fiber (2) extends in a preset direction. A preset position is provided in the extension length of the optical fiber (2), and a Bragg grating (21) is formed at the preset position. The magnetic component (1) is connected to the preset position of the optical fiber (2). The magnetic component (1) can generate a position offset under the action of magnetic force, so as to allow the Bragg grating (21) at the preset position to produce a bending deformation perpendicular to the preset direction. The magnetic field strength measuring apparatus comprises the optical fiber sensor. The optical fiber sensor aims to solve the technical problem of inaccurate magnetic field strength measurements caused by the use of a current-carrying conductor, which is susceptible to electromagnetic and radio frequency interference.
G01R 15/24 - Adaptations fournissant une isolation en tension ou en courant, p. ex. adaptations pour les réseaux à haute tension ou à courant fort utilisant des dispositifs modulateurs de lumière
G01R 33/00 - Dispositions ou appareils pour la mesure des grandeurs magnétiques
G01R 33/032 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs magnéto-optiques, p. ex. par effet Faraday
84.
Chiral TACN/NOTA compounds/derivatives with and without metals for application
Cyclic 1,4,7-triazacyclononane-1,4,7-triacetic acid chelators and metal complexes comprising the same useful as positron emission tomography imaging agents, magnetic resonance imaging contrast agents, and computed tomography imaging agents, and optical imaging agents, and methods of use and preparation thereof.
C07D 403/14 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
C07D 255/02 - Composés hétérocycliques contenant des cycles comportant trois atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par les groupes non condensés avec d'autres cycles
C07D 401/14 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant au moins trois hétérocycles
85.
Microfluidic-based Device For In Vivo Wound Infection Model And Uses Thereof
The present invention provides an integrated microfluidic-based device for establishing a wound infection in vivo model suitable for high throughput bioassay such as potential drug screening, in vivo dosing optimization, host-microbe or microbe-microbe interactions under the influence of specific agents of interest, and studying regulatory mechanisms of certain inflammatory diseases relating to or arising from the wound infection. The present invention allows direct qualitative and quantitative assessments of specific markers expressed due to the wound infection by one or more microbes devoid of cell sorting, isolation, or labelling as in other conventional in vivo models or methods.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
86.
TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION DEVICE WITH THERMAL MODALITIES FOR STIMULATING ACUPOINTS OF A USER
A head-mount transcutaneous electrical nerve stimulation (TENS) device adapted to stimulate acupoints of a user transcutaneously when being worn on the head of the user is disclosed. The TENS device includes one or more frames, a plurality of contacts, a pulse width modulation (PWM) generator, and one or more thermal pads. The one or more frames are arranged to have a contour matching an anatomical shape of the head. The plurality of contacts is arranged on an inner surface of the one or more frames for contacting the acupoints on the head. The PWM generator is configured to generate a pulse stimulation signal and couple the pulse stimulation signal to the plurality of contacts for stimulating the acupoints. The one or more thermal pads are arranged on the inner surface of the one or more frames for applying thermal treatment to the acupoints.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
87.
Weakly-Supervised System, Method and Workflow for Processing Whole Slide Image for Disease Detection
In generating training and testing datasets for machine learning, manual annotation of a large volume of data is impractical and expensive. A machine-learning model for detecting carcinoma (CA) from a whole slide image (WSI) processes average cellular features of cells identified on the WSI. Each cellular feature is a descriptive statistic of the cells, advantageously allowing the training and testing datasets to be constructed without a costly annotation process of pixelwise labelling each cell on a WSI training sample. Apart from predicting a CA case or a non-CA case for the WSI, the machine-learning model is also usable to: identify a suspicious CA case for priority assessment if a non-CA case is predicted for the WSI; generate a tumor probability heatmap of the WSI for visualizing potential CA regions on the WSI to assist pathological assessment; and assess quality control of a triage system before implementation in clinical setting.
Provided are an installation auxiliary tool for blind bolts, an installation kit and a use method therefor. The installation auxiliary tool for blind bolts (100) comprises a clamping assembly (10), a connection assembly (20), an elastic member (60) and a force transmission member (50). The clamping assembly (10) comprises two clamping arms (11), the two clamping arms (11) being arranged opposite to each other in a spaced-apart manner, and one end of each clamping arm (11) being a clamping end (111). Two ends of the connection assembly (20) are respectively and rotatably connected to the two clamping arms (11). Two ends of the elastic member (60) are respectively connected to the two clamping arms (11), and are used for driving the clamping ends (111) of the two clamping arms (11) to approach each other. The force transmission member (50) is located between the two clamping arms (11) and is in threaded connection with the connection assembly (20). The installation kit comprises a blind bolt (100) and said installation auxiliary tool, said installation auxiliary tool being used for assisting in installing the blind bolt (100). During use of the said installation auxiliary tool, the force transmission member (50) is rotated to convert the torque of the force transmission member (50) into an axial force, so as to easily push the blind bolt (100) to pass through an installation hole, thus effectively reducing physical exertion of operators, and helping to reduce the workload of the operators.
B25B 27/14 - Outils à main ou outillage d'établi, spécialement conçus pour assembler ou séparer des pièces ou des objets, que cela entraîne ou non une certaine déformation, non prévus ailleurs pour assembler des objets autrement que par ajustage à la presse, ou pour les détacher
F16B 13/06 - Chevilles ou autres dispositifs fixés à des parois ou autres emplacements par insertion dans des trous préparés à cet effet avec parties s'agrippant dans le trou ou derrière la paroi après insertion et combinées avec un manchon extensible
89.
SYSTEM AND METHODS FOR PRECISION TUMOR DELINEATION IN CANCER TREATMENT OR DIAGNOSIS FOR SUBJECTS WITH CARCINOMA BASED ON CONTRAST AGENT-FREE, VIRTUAL CONTRAST-ENHANCED MRI DATA
The present disclosure provides a system and method for precision tumor delineation in cancer treatment or diagnosis for subjects with carcinoma, in particular, nasopharyngeal carcinoma, based on contrast agent-free, virtual contrast-enhanced MRI data (VCE-MRI) synthesized by a modified multimodality-guided synergistic neural network trained with a more diversified training dataset and having a higher generalizability by minimizing data distribution variation between an external dataset and the training dataset through a data distribution matching mechanism before VCE-MRI synthesis.
The present application relates to the technical field of 3D materials, and in particular, to a composite 3D printing material containing tea residues, a preparation method therefor and a use thereof. The provided composite 3D printing material containing tea residues comprises the following components in percentage by weight: 70-95% of a resin matrix and 5-30% of tea residues. It is ensured that the obtained composite 3D printing material has high tensile strength and maintains certain toughness, so that the composite 3D printing material containing tea residues can well meet the relevant technical requirements of FDM 3D printing, and realize a high printing success rate during the FDM 3D printing. Therefore, the provided composite 3D printing material containing tea residues achieves high value-added recycling of the tea residues, and is beneficial to environmental protection and cost reduction; additionally, the provided composite 3D printing material containing tea residues can better meet the functional requirements of routine 3D printing, and printed products have excellent comprehensive performance and a wide range of applications.
CENTRE FOR EYE AND VISION RESEARCH LIMITED (Chine)
THE HONG KONG POLYTECHNIC UNIVERSITY (Chine)
Inventeur(s)
Lam, Chuen
Tse, Yan Yin
Wang, Jia Jun
Bian, Jing Fang
Zuo, Bing
To, Chi Ho
Abrégé
A novel pharmacologic treatment of refractive disorders including myopia and hyperopia is provided. The method of treating refractive disorders including myopia and hyperopia is mainly through targeting the Hippo biological pathway using agonists, antagonists or gene therapy targeting the HIPPO signaling, including MST1/MST2, LATS1/LATS2 kinases, and YAP/TAZ proteins. It is also found that the drug XMU-MP-1, a reversible and selective inhibitor of MST1/2, is a promising drug to target the Hippo biological pathway.
A61K 31/5517 - 1,4-Benzodiazépines, p. ex. diazépam condensées avec des cycles à cinq chaînons ayant l'azote comme hétéro-atome d'un cycle, p. ex. imidazobenzodiazépines, triazolam
In an indoor environment on fire, automatic deployment of sensors disposed on, beneath or over the floor to look upward the ceiling to observe a body of smoke and flame risen near the ceiling allows important information regarding states and dynamics of the body of smoke and flame to be gathered at an early stage of fire (e.g. before arrival of firefighters). By distributing the sensors over the indoor environment, the states and dynamics of the body of smoke and flame are monitored holistically (i.e. as a whole) even at the early stage of fire. Such information is useful to predict development of the fire. In one implementation, a sensor is held in an infrastructure sensor holder mounted on the ceiling during normal time. Upon detecting occurrence of fire, the sensor drops from the holder to land on the floor and orients a sensing direction vertically upward to perform monitoring.
G01K 3/14 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des différences de valeursThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs différenciées par rapport à l'espace
A62C 3/00 - Prévention, limitation ou extinction des incendies spécialement adaptées pour des objets ou des endroits particuliers
A62C 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
G01K 13/00 - Thermomètres spécialement adaptés à des fins spécifiques
H04Q 9/00 - Dispositions dans les systèmes de commande à distance ou de télémétrie pour appeler sélectivement une sous-station à partir d'une station principale, sous-station dans laquelle un appareil recherché est choisi pour appliquer un signal de commande ou pour obtenir des valeurs mesurées
93.
PIEZOELECTRIC-PHOTOVOLTAIC INTEGRATED APPARATUS, PREPARATION METHOD, AND APPLICATION
A piezoelectric-photovoltaic integrated apparatus, a preparation method, and an application. The piezoelectric-photovoltaic integrated apparatus comprises a piezoelectric assembly and a photovoltaic assembly, wherein the piezoelectric assembly comprises a first piezoelectric electrode, a piezoelectric active layer and a second piezoelectric electrode; the photovoltaic assembly comprises a first photovoltaic electrode, a photovoltaic active layer, a hole transport layer and a second photovoltaic electrode; and in the direction from an outer layer to an inner layer, the second photovoltaic electrode, the hole transport layer, the photovoltaic active layer, the first photovoltaic electrode, the second piezoelectric electrode, the piezoelectric active layer and the first piezoelectric electrode are sequentially arranged in a cladding manner. A piezoelectric assembly and a photovoltaic assembly are integrated, thereby solving the problems in the prior art of a photovoltaic conversion device and a piezoelectric conversion device having the defect of intermittent power supply, and thus the application scenarios being limited. A two-dimensional/three-dimensional tin-based perovskite material is used for a photovoltaic active layer, so that the photovoltaic conversion efficiency is high, the properties are stable, and minor harm is caused. The apparatus can be widely applied to fabrics, wearable devices, mobile devices and sensors.
H10N 30/30 - Dispositifs piézo-électriques ou électrostrictifs à entrée mécanique et sortie électrique, p. ex. fonctionnant comme générateurs ou comme capteurs
94.
COMPOSITE WRAPPED STEEL BAR AND MANUFACTURING METHOD THEREFOR, ON-SITE BENDING METHOD, AND APPLICATION
The present application provides a composite wrapped steel bar and a manufacturing method therefor, an on-site bending method, and an application. The composite wrapped steel bar comprises a steel bar of a core portion and a composite protection layer wrapped around the surface of the steel bar. The composite wrapped steel bar of the present application has the characteristics of corrosion resistance, impact resistance, peeling resistance, good bonding performance with concrete, and a price–performance ratio, etc. A concrete structure is enhanced by using the composite wrapped steel bar provided by the present application, so that the durability of the structure can be significantly improved, and the service life of the structure can be prolonged. The composite wrapped steel bar provided by the present application is suitable for infrastructure construction in corrosive environments, for concrete structures obtained by directly mixing sea water and sea sand, and for the construction of offshore islands and reefs having national defense and economic value.
Provided is a microbial system established based on a genetically modified bacterial strain under a genus of Pseudomonas with improved capacities to form more biofilms and trap more microplastics from a source than its wild-type form. In particular, the genetically modified bacterial strain is selected from P. aeruginosa, and the genetically modified P. aeruginosa is provided by adaptive mutation to a gene responsible for regulating an adhesion protein expression in an exopolymeric matrix of the biofilms. A method for recovering the microplastics trapped by the biofilms of this genetically modified bacterial strain is also provided.
Embodiments of the present disclosure provide a fuel cell power generation device, which includes: a fuel cell with an anode and a cathode, for decomposing hydrogen and generating electric energy through reaction of decomposed hydrogen and oxygen; a first delivery pipe connected between a pipeline of a hydrogen-containing gas and the fuel cell, for delivering the hydrogen-containing gas to the anode of the fuel cell; a first output pipe connected to the fuel cell, for discharging a first remaining gas contacted with the anode of the fuel cell; a second delivery pipe connected to the fuel cell, for delivering an oxygen-containing gas to the cathode of the fuel cell; and a second output pipe connected to the fuel cell, for discharging a second remaining gas contacted with the cathode of the fuel cell.
Sustainable upcycling method of preparing an electrocatalyst, the method including: providing an electrode material obtained from a lithium-ion battery, wherein the electrode material includes LiFePO4@N-doped carbon core-shell particles; contacting the electrode material with an aqueous solution comprising an acid thereby forming the electrocatalyst; and optionally drying the electrocatalyst.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
98.
FUNCTIONALIZED NANO-SELENIUM HYDROSOL AND USE THEREOF IN TREATING NEURODEGENERATIVE DISEASES
A61K 33/04 - Soufre, sélénium ou tellureLeurs composés
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
44@N-doped carbon core-shell particles; contacting the electrode material with an aqueous solution comprising an acid thereby forming the electrocatalyst; and optionally drying the electrocatalyst.
H01M 4/90 - Emploi de matériau catalytique spécifié
H01M 12/08 - Éléments hybridesLeur fabrication composés d'un demi-élément du type élément à combustible et d'un demi-élément du type à élément secondaire
100.
METHOD AND COMPOSITION FOR TREATING NON-ALCOHOLIC FATTY LIVER DISEASE, ASSOCIATED CONDITIONS AND SYMPTOMS
The present invention provides a method for treating non-alcoholic fatty liver disease (NAFLD), associated conditions and symptoms. In particular, the method includes administering to a subject suffering from or susceptible to NAFLD a composition including therapeutic nucleic acids to reduce G protein-coupled receptor 110 (GPR110) expression in liver. The present invention also provides a pharmaceutical composition for treating NALFD or alleviating conditions and symptoms associated therewith.
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
