Abrégé

The disinfectant-dosing microgel is formed from a mixture of a sol and a solution of a disinfecting and deodorizing agent. In use, the sol phase is transformed, by various conditions, into an active microgel. The disinfectant-dosing microgel is applied to the waste, such as by spraying, mixture therewith or the like. The combination of the sol and the solution of the disinfecting and deodorizing agent or, alternatively, the combination of the polymer and the solution of the disinfecting and deodorizing agent, is triggered to transform from the sol phase into the active microgel for long-term disinfection and deodorization of the waste by the temperature, pH, and/or salt concentration of the waste. The transformation to the active microgel for long-term disinfection and deodorization of the waste can also be initiated by adding chemical substances to alter the pH or promote gelation, either before, during or after application to the waste.

Classes IPC  ?

• A01N 59/16 - Métaux lourdsLeurs composés
• A01N 25/04 - Dispersions ou gels
• A01N 25/08 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des solides comme supports ou diluants
• A01N 25/10 - Composés macromoléculaires
• A01N 31/08 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques de l'oxygène ou du soufre l'atome d'oxygène ou de soufre étant lié directement à un système cyclique aromatique
• A01N 33/12 - Composés d'ammonium quaternaire
• A01N 37/04 - Acides carboxyliques saturés ou leurs thio-analoguesLeurs dérivés polybasiques
• A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
• A01N 59/02 - SoufreSéléniumTellureLeurs composés
• A01N 59/20 - Cuivre
• A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges

Abrégé

A backlight for a liquid crystal display (LCD) includes: a waveguide configured to receive a collimated RGB beam; a plurality of color-selective diffractive gratings disposed on the waveguide, wherein each color-selective diffractive grating of the plurality of color-selective diffractive gratings is configured to out-couple a beam of a single color from the waveguide; and a beam in-coupler configured to adjust an angle of incidence into the waveguide with respect to the collimated RGB beam.

Classes IPC  ?

• F21V 8/00 - Utilisation de guides de lumière, p. ex. dispositifs à fibres optiques, dans les dispositifs ou systèmes d'éclairage

Abrégé

A method for enhancing controllability on switching speed of an electronic cascode power device comprising a high-voltage normally-ON transistor having a drain connected to the high-side terminal of the cascode power device and a gate connected to the low-side terminal and a low-voltage normally-OFF transistor having a drain connected to a source of the high-voltage normally-ON transistor, a source connected to the low-side terminal of the cascode power device and a gate connected to the control terminal of the cascode power device; the method comprises introducing a coupling capacitor into the electronic cascode power device by: connecting a first terminal of the coupling capacitor to the source of the high-voltage normally-ON transistor; and connecting a second terminal of the coupling capacitor to the gate of the low-voltage normally-OFF transistor.

Classes IPC  ?

• H03K 17/04 - Modifications pour accélérer la commutation

Abrégé

A method for dry etching to fabricate an AlGaAs optical waveguide is provided. The method includes steps as follows: providing at least one AlGaAs-on-insulator substrate(100) which comprising a substrate layer(102), a buried layer(104) formed over the substrate layer(102), a bonding interlayer(106) formed over the buried layer(104), and an AlGaAs layer(108) formed over the bonding interlayer(106), forming a hardmask film (110)on the AlGaAs layer(108), forming a photoresist film (112)on the hardmask film(110), transferring a pattern to the photoresist film(112), etching the hardmask film(110) to transfer the pattern from the photoresist film(112) to the hardmask film(110), and etching the AlGaAs layer(108) using ICP-RIE with Ar plasma to form a waveguide structure having a trapezoidal-shaped upper portion with positive slope sidewalls and a horizontally extending lower portion for the AlGaAs layer(108), wherein only physical bombardment of Ar + ions is applied to the AlGaAs layer(108) to pattern the waveguide structure.

Classes IPC  ?

• G02B 6/136 - Circuits optiques intégrés caractérisés par le procédé de fabrication par gravure
• H01L 21/3065 - Gravure par plasmaGravure au moyen d'ions réactifs

Abrégé

The elastocaloric cooling device (10) includes a plurality of elastocaloric modules (12, 14, 16, 18, 20), where each of the elastocaloric modules (12, 14, 16, 18, 20) has at least one tube (52) embedded in a retainer (54). The at least one tube (52) is formed from a shape memory alloy. A pump (30) is in fluid communication with each of the elastocaloric modules (12, 14, 16, 18, 20) for driving a heat transfer fluid (HTF) through the at least one tube (52) of each of the elastocaloric modules (12, 14, 16, 18, 20) with a cyclic alternating direction of fluid flow. The plurality of elastocaloric modules (12, 14, 16, 18, 20) are fluidly connected in parallel such that the fluid flow of the heat transfer fluid (HTF) through the at least one tube (52) of each of the elastocaloric modules (12, 14, 16, 18, 20) is simultaneous and identical.

Classes IPC  ?

• F25B 23/00 - Machines, installations ou systèmes ayant un seul principe de fonctionnement non compris dans les groupes , p. ex. utilisant l'effet de radiation sélective
• F25B 49/00 - Disposition ou montage des dispositifs de commande ou de sécurité

Abrégé

A nanopositioning device capable of positioning objects with nanometer scale accuracy is provided. The nanopositioning device includes a carriage component and an actuator coupled to the carriage component through an axle for controlling a position of the carriage component with respect to the actuator precisely. The carriage component includes a front clamp and a rear clamp. The carriage component is displaceable relative to the axle, which is attached to a base. The actuator includes piezoelectric stacks and the axle extended from the piezoelectric stacks to couple to the front clamp and the rear clamp to stick-slip drive the carriage component. The axle includes a plurality of ceramic plates. Each of the plurality of ceramic plates is polished and made of a ceramic material. The plurality of ceramic plates are in contact with the front clamp and the rear clamp to realize a friction interface for driving the carriage component.

Classes IPC  ?

• H02N 2/02 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction produisant un mouvement linéaire, p. ex. actionneursPositionneurs linéaires
• H02N 2/04 - Détails de structure
• H02N 2/06 - Circuits d'entraînementDispositions pour la commande
• H10N 30/853 - Compositions céramiques

Abrégé

The present invention provides a system and a method for estimating object properties. The system comprises a multi-finger end effector equipped with tactile sensors capable of detecting normal and tangential forces at multiple contact points and enabling 3D interactive actions to gather comprehensive tactile information; an information processing unit including an action selector for dynamically generating action sequences based on prior knowledge of the object and desired properties and a property estimator for analysing collected tactile data to estimate object properties; and a data management unit for providing prior data for action selection and property estimation and saving new results and inputted parameters. By leveraging multi-point, multi-directional sensing, variable 3D testing actions, and multiple data-based estimation, this invention enhances the scope of object property estimation, addressing limitations of conventional tactile sensing approaches.

Classes IPC  ?

• B25J 9/16 - Commandes à programme
• B25J 13/08 - Commandes pour manipulateurs au moyens de dispositifs sensibles, p. ex. à la vue ou au toucher
• B25J 15/08 - Têtes de préhension avec des éléments en forme de doigts
• B25J 19/04 - Dispositifs sensibles à la vue

Abrégé

Spirocyclic compounds, including chiral spiro diamine, chiral spiro amino naphthol, chiral spiro bis(indole), chiral spiro diaryl diol, chiral spiro diaryl diamine, chiral spiro amino naphthol, chiral spiro diaryl diindole, and chiral spiro phospholane useful as chiral ligands and chiral organocatalysts and methods of preparation and methods of use thereof. Owing to the molecular shape and three-dimensional orientation, the chiral diamine and chiral amino naphthol molecules provide a skeleton for use as ligands and organocatalysts.

Classes IPC  ?

• B01J 31/24 - Phosphines
• B01J 31/18 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination contenant de l'azote, du phosphore, de l'arsenic ou de l'antimoine
• C07C 275/30 - Dérivés d'urée, c.-à-d. composés contenant l'un des groupes les atomes d'azote ne faisant pas partie de groupes nitro ou nitroso ayant des atomes d'azote de groupes urée liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné étant substitué de plus par des atomes d'halogène ou par des groupes nitro ou nitroso
• C07C 335/18 - Dérivés de thiourée ayant des atomes d'azote de groupes thiourée liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné étant substitué de plus par des atomes d'oxygène liés par des liaisons simples
• C07D 209/12 - Radicaux substitués par des atomes d'oxygène
• C07D 263/12 - Composés hétérocycliques contenant des cycles oxazole-1, 3 ou oxazole-1, 3 hydrogéné non condensés avec d'autres cycles comportant une liaison double entre chaînons cycliques ou entre chaînon cyclique et chaînon non cyclique avec uniquement des atomes d'hydrogène, des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués, liés directement aux atomes de carbone du cycle avec des radicaux contenant uniquement des atomes d'oxygène et de carbone
• C07F 9/54 - Composés de phosphonium quaternaire
• C07F 9/572 - Cycles à cinq chaînons
• C07F 9/6574 - Esters des oxyacides du phosphore

Abrégé

The present invention relates to a secondary battery and a manufacturing method therefor, and an electric device. The secondary battery comprises a negative electrode sheet and a gel electrolyte; the negative electrode sheet contains a negative electrode active material; the negative electrode active material comprises a carbon-containing material; the gel electrolyte comprises a polymer, an organic solvent, and an electrolyte salt; the organic solvent comprises one or more of an ether-based organic solvent, a sulfone-based organic solvent, a phosphate-based organic solvent, and a carbonate-based organic solvent; the polymer comprises one or more of a carbon-oxygen double bond and a carbon-oxygen single bond; and the mass ratio of the polymer in the gel electrolyte is 0.5%-38%.

Classes IPC  ?

• H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
• H01M 10/058 - Structure ou fabrication

Abrégé

Architectures and techniques are provided for improved vibration compensation for a boom lift-robot-mounted (BLMR) system, which can result in improved BLMR operating precision and safety at a reduced cost. Boom lifts typically contain extendable large-scale, variable-stiffness structures, subject to complex nonlinear static deformation and dynamic motion/gust-induced vibrations. Said vibrations can be compensated for at an end effector of a robot via a Jacobian-based vibration compensation via IMU (JVCI) procedure. The output of the JVCI procedure can rely on IMU feedback and can be combined with other vibration-mitigation techniques, including various feedforward techniques.

Classes IPC  ?

• B25J 9/16 - Commandes à programme

Abrégé

The invention provides an electronic cascode power device. The electronic cascode power device has a high-side terminal, a low-side terminal and a control terminal. The electronic cascode power device comprises: a high-voltage silicon (Si) super-junction MOSFET with a drain connected to the high-side terminal of the cascode device; a low-voltage gallium nitride (GaN) HEMT with a drain connected to a source of the high-voltage Si super-junction MOSFET, a source connected to the low-side terminal of the cascode device and a gate connected to the control terminal of the cascode device; and an overvoltage clamping circuit connected between the drain and source of the low-voltage GaN HEMT. The provided cascode structure can effectively suppress the reverse-recovery process of super-junction MOSFET, achieving nearly 50% reduction in overall switching loss at high current levels.

Classes IPC  ?

• H10D 80/20 - Ensembles de plusieurs dispositifs comprenant au moins un dispositif couvert par la présente sous-classe l’au moins un dispositif étant couvert par les groupes , p. ex des ensembles comprenant des condensateurs, des transistors FET de puissance ou des diodes Schottky
• H10D 8/25 - Diodes Zener
• H10D 30/47 - Transistors FET ayant des canaux à gaz de porteurs de charge de dimension nulle [0D], à une dimension [1D] ou à deux dimensions [2D] ayant des canaux à gaz de porteurs de charge à deux dimensions, p. ex. transistors FET à nanoruban ou transistors à haute mobilité électronique [HEMT]
• H10D 62/824 - Hétérojonctions comprenant uniquement des hétérojonctions de matériaux du groupe III-V, p. ex. des hétérojonctions GaN/AlGaN
• H10D 62/85 - Corps semi-conducteurs, ou régions de ceux-ci, de dispositifs ayant des barrières de potentiel caractérisés par les matériaux étant des matériaux du groupe III-V, p. ex. GaAs

Abrégé

A rotary solid-state refrigeration driver based on recovery of mechanical work of unloading, and a solid-state refrigeration apparatus. The rotary solid-state refrigeration driver comprises: a rotary motor (9), a main transmission shaft (2) driven by the rotary motor (9) to rotate, N eccentric transmission mechanisms mounted at different axial positions of the main transmission shaft (2), N pistons (1) respectively driven by the N eccentric transmission mechanisms to move in a reciprocating manner, and N elastocaloric materials (10) periodically loaded and unloaded by means of the reciprocating motion of the N pistons (1), wherein the N eccentric transmission mechanisms have different phase angles, such that the N elastocaloric materials (10) are unloaded in different time periods; and during a process of being unloaded, each elastocaloric material (10) releases its own mechanical work to provide thrust for the rotation of the main transmission shaft (2), N being an integer greater than one.

Classes IPC  ?

• F25B 23/00 - Machines, installations ou systèmes ayant un seul principe de fonctionnement non compris dans les groupes , p. ex. utilisant l'effet de radiation sélective
• F25B 17/08 - Machines, installations ou systèmes à sorption, à marche discontinue, p. ex. à absorption ou à adsorption l'absorbant ou l'adsorbant étant un solide, p. ex. du sel
• F28D 17/00 - Appareils échangeurs de chaleur de régénération dans lesquels un agent ou une masse intermédiaire immobile de transfert de chaleur est mis en contact successivement avec chacune des sources de potentiel calorifique, p. ex. en utilisant des particules granulées
• F25D 31/00 - Autres appareils de refroidissement ou de congélation

Abrégé

There is provided a method of managing carbon data using a blockchain network. The method includes categorizing, by a processing device, each of one or more carbon data received from at least one user of the blockchain network into respective privacy levels. Each of the respective privacy levels represents a privacy requirement corresponding to each of the one or more carbon data. The method further includes encrypting, by the processing device, each of the one or more categorized carbon data using one of a plurality of encryption schemes. The one of the plurality of encryption schemes is determined based on the privacy level of the carbon data. The method further includes generating, by the processing device, one or more blockchain transactions corresponding to each of the one or more encrypted carbon data and transmitting, by the processing device, the one or more blockchain transactions into the blockchain network.

Classes IPC  ?

• H04L 9/00 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité

Abrégé

A system includes a first device and a second device. The first device and the second device are connected via a communication channel. The first device is configured to send a codeword to the second device via the communication channel. The second device is configured to: obtain a vector of channel observation values via the communication channel, wherein the vector includes a corrupted codeword; compute a syndrome of the vector; and combine the syndrome with a plurality of pre-computed syndromes of test error patterns (TEPs) to decode the corrupted codeword.

Classes IPC  ?

• H04L 1/00 - Dispositions pour détecter ou empêcher les erreurs dans l'information reçue

Abrégé

An automated dry-heating bedbug eradication device for pest eradication is provided herewith. By the use of a specifically fabricated graphene-coated copper heating film, the dry-heating device of the present invention can readily achieve a temperature that is higher than the well-established temperature of 45° C., which is proven lethal to all life stages of bedbugs, and also effective in ant eradication. The device is carefully designed to achieve high portability and maneuverability, and is customizable to accommodate the needs to sanitize mattresses of different sizes in different settings, ranging from home use to commercial hotel or hostel uses. The device of the present invention is also equipped with wireless connectability to mobile applications, and infrared sensor and PID systems for remote real-time monitoring and control.

Classes IPC  ?

• A01M 1/20 - Capture ou destruction des insectes par les poisons, les narcotiques ou le feu
• B25J 5/00 - Manipulateurs montés sur roues ou sur support mobile
• B25J 11/00 - Manipulateurs non prévus ailleurs

Abrégé

A one-part adhesive composition useful for sealing threaded articles, wherein the one-part adhesive composition includes a plurality of microcapsules and a dispersion matrix, wherein each of the plurality of microcapsules comprise a core and a shell at least partially enclosing the core, wherein the core includes a polyamine and the shell comprises a crosslinked polyurea; and the dispersion matrix comprises an epoxy resin; a method of use thereof; and products thereof.

Classes IPC  ?

• C09J 163/00 - Adhésifs à base de résines époxyAdhésifs à base de dérivés des résines époxy
• C09J 5/06 - Procédés de collage en généralProcédés de collage non prévus ailleurs, p. ex. relatifs aux amorces comprenant un chauffage de l'adhésif appliqué
• C09J 11/08 - Additifs macromoléculaires

Abrégé

A space-time multiport antenna system is provided. The space-time multiport antenna system includes an antenna array, a plurality of feed ports, and a controller. The antenna array includes a plurality of antenna elements. The feed ports are connected to the antenna elements, respectively. The controller is connected to the antenna array via the feed ports and configured to control the antenna elements for dynamically switching states of the antenna elements. Each pair of the adjacent antenna elements form a unit, and, in anyone of the units and at any given time, only one of the antenna elements is active and another one of the antenna elements is in a non-active state. The proposed controller can be applied to different types of antennas, providing a general technique to reduce mutual coupling of closely-spaced antennas significantly.

Classes IPC  ?

• H01Q 9/04 - Antennes résonnantes
• H01Q 1/52 - Moyens pour réduire le couplage entre les antennesMoyens pour réduire le couplage entre une antenne et une autre structure
• H01Q 5/314 - Éléments rayonnants individuels ou couplés, chaque élément étant alimenté d’une façon non précisée utilisant des circuits ou des composants dont la réponse dépend de la fréquence, p. ex. des circuits bouchon ou des condensateurs
• H01Q 21/24 - Combinaisons d'unités d'antennes polarisées dans des directions différentes pour émettre ou recevoir des ondes polarisées circulairement ou elliptiquement ou des ondes polarisées linéairement dans n'importe quelle direction

Abrégé

A photoalignment layer useful in the fabrication of liquid crystals including at least one precursor compound, wherein the at least one precursor compound includes a phosphonic acid anchor moiety and a dimerizable or polymerizable moiety, a method of preparing a photoalignment layer including a dimerized or polymerized compound, and products thereof.

Classes IPC  ?

• G02F 1/1337 - Orientation des molécules des cristaux liquides induite par les caractéristiques de surface, p. ex. par des couches d'alignement

Abrégé

A privacy-preserving neural graph database system is provided for receiving a user query and delivering an answer. The system includes: a user query input receiver, a graph builder module, a query encoder model, a privacy risk identifier, a score calculator engine, and an answer output module. The input receiver captures queries in structured language. The graph builder constructs a computational graph as a directed acyclic graph using queries, where edges represent operations on entities and attributes. The query encoder converts the queries into a vector format. The answer retriever module receives the vector format of the query and retrieves candidate answer sets to the queries. The privacy risk identifier classifies the results into public and privacy answer sets and flags potential privacy breaches. The score calculator evaluates these sets with loss functions. The answer output module selects the final answer based on these evaluations.

Classes IPC  ?

• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès
• G06F 16/245 - Traitement des requêtes
• G06F 16/901 - IndexationStructures de données à cet effetStructures de stockage

Abrégé

An automatic feeder apparatus for feeding a rodent in a cage is provided. The automatic feeder apparatus comprises a food container for holding food, and the food container comprises an accessible region and a blocked region. The food container is configured to be automatically switchable between an accessible state, in which the food is accessible to the rodent, and a blocked state, in which the food is blocked from access to the rodent.

Classes IPC  ?

• A01K 5/02 - Systèmes automatiques
• A01K 1/03 - Logements pour animaux domestiques ou de laboratoire
• A01K 1/035 - Dispositifs utilisés pour l'élevage d'animaux domestiques, p. ex. accessoires pour logements ou lits pour chiens

Abrégé

The subject invention pertains methods for the ectopic expression of a transmembrane protein lacking plasma membrane expression in a heterologous cell line. In embodiments, transmembrane proteins Fyn-TMC1 and/or Fyn-TMC2 are fused to a membrane-anchoring motif, a Fyn lipidation tag, which provides a signal for myristoylation and palmitoylation, allowing further research on these proteins, including but not limited to their function, structure, and drug screening.

Classes IPC  ?

• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

The subject invention pertains to compositions and methods for inhibiting IGF2 signaling. Insulin-like growth factor 2 (IGF2) is a key signaling molecule that plays important roles in various physiological processes, including skeletal myogenesis during development and adult muscle remodeling. Abnormal activation of the signaling pathway induced by IGF2 has been shown to promote cancer progression. TMED10, a p24 family protein, functions as a cargo receptor, promoting the export of IGF2 from the endoplasmic reticulum (ER) via recognizing an ER export signal on IGF2. Moreover, TMED10 also mediates ER export of sortilin, which is important to regulate the export of IGF2 from the trans-Golgi network. The subject invention features a novel therapeutic strategy for cancer treatment, that includes, but is not limited to, inhibitors targeting the interaction between IGF2 and TMED10.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 38/30 - Facteurs de croissance analogues à l'insuline, c.-à-d. somatomédines, p. ex. IGF-1, IGF-2
• C12N 9/22 - Ribonucléases
• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées

Abrégé

A semiconductor device includes a buffer layer, a barrier layer, a nitride-based semiconductor layer, an isolation layer, and a gate electrode. The barrier layer is disposed on the buffer layer. The nitride-based semiconductor layer is disposed on the barrier layer and has a channel region and a doped region abutting against each other. The isolation layer covers the nitride-based semiconductor layer. The isolation layer and doped channel region can exhibit a type-II energy band alignment (staggered gate stack). The gate electrode is disposed over the isolation layer and the nitride-based semiconductor layer.

Classes IPC  ?

• H10D 30/47 - Transistors FET ayant des canaux à gaz de porteurs de charge de dimension nulle [0D], à une dimension [1D] ou à deux dimensions [2D] ayant des canaux à gaz de porteurs de charge à deux dimensions, p. ex. transistors FET à nanoruban ou transistors à haute mobilité électronique [HEMT]
• H10D 30/01 - Fabrication ou traitement
• H10D 62/10 - Formes, dimensions relatives ou dispositions des régions des corps semi-conducteursFormes des corps semi-conducteurs
• H10D 62/17 - Régions semi-conductrices connectées à des électrodes ne transportant pas de courant à redresser, amplifier ou commuter, p. ex. régions de canal
• H10D 62/824 - Hétérojonctions comprenant uniquement des hétérojonctions de matériaux du groupe III-V, p. ex. des hétérojonctions GaN/AlGaN
• H10D 64/27 - Électrodes ne transportant pas le courant à redresser, à amplifier, à faire osciller ou à commuter, p. ex. grilles

Abrégé

A pair of light rays spatially-sheared with a controllable beam-shear distance is generated by a module having a beamsplitter (BS) and two mirrors. The BS splits an input light ray into first and second split light rays respectively propagated on first and second light paths. The two mirrors are respectively located at distal ends of the two light paths, and cause each split light ray to undergo a two-stage reflection, thereby generating first and second reflected light rays directed to the BS. The BS processes the two reflected light rays to generate the pair of spatially-sheared light rays. Orientations of the two mirrors in yaw angle, pitch angle, or both, are jointly adjustable to realize and control the beam-shear distance without using any birefringent crystal-based prism. The module is used to form differential interference contrast (DIC) microscopes providing variable shear distances, advantages of orientation independence, etc.

Classes IPC  ?

• G01J 9/02 - Mesure du déphasage des rayons lumineuxRecherche du degré de cohérenceMesure de la longueur d'onde des rayons lumineux par des méthodes interférométriques
• G02B 21/00 - Microscopes

Abrégé

A method for inhibiting leukocyte receptor tyrosine kinase (LTK), comprising bringing an inhibiting-effective amount of a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof into contact with leukocyte receptor tyrosine kinase (LTK).

Classes IPC  ?

• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• C07D 487/04 - Systèmes condensés en ortho
• C07D 498/00 - Composés hétérocycliques contenant dans le système condensé au moins un hétérocycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle
• C07D 513/00 - Composés hétérocycliques contenant dans le système condensé au moins un hétérocycle comportant des atomes d'azote et de soufre comme uniques hétéro-atomes du cycle, non prévus dans les groupes , ou
• C07D 413/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 417/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre et d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• A61P 35/00 - Agents anticancéreux

Abrégé

A stretchable electrical interconnect comprises: a curved wall that is stretchable lengthwise towards two ends of the curved wall, wherein the curved wall has a height that extends perpendicularly to a plane in which the two ends of the curved wall extend, and wherein the two ends of the curved wall are configured to be connectable to one or more electronic devices.

Classes IPC  ?

• B81B 7/00 - Systèmes à microstructure
• B81C 1/00 - Fabrication ou traitement de dispositifs ou de systèmes dans ou sur un substrat

Abrégé

A system includes a text receiver, a rule-based privacy checklist module, a personalized learning module, and a reasoning module. The text receiver converts user input into a machine-readable format. The rule-based privacy checklist module retrieves privacy norms from a database, processes these norms into annotated rules, and compares input data against them to create a structured report. The personalized learning module, using a fine-tuned BERT, classifies contextual information for privacy violations and generates a local privacy report. The reasoning module integrates multi-turn dialogues, applies chain-of-thought reasoning to evaluate the entire context for private information, and delivers comprehensive cloud-based privacy judgments and reports.

Classes IPC  ?

• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès

Abrégé

A method is provided for charging one or more electric vehicles. The method comprising: receiving, by a master charging pile, real-time available current information related to a main power supply; receiving, by the master charging pile, latest charging current information related to the master charging pile and one or more slave charging piles, the latest charging current information comprising charging modes and a list of requested charging current for the master charging pile and the one or more slave charging piles; generating, by the master charging pile, charging control signals by processing the real-time available current information and the latest charging current information by applying a load balancing algorithm; and applying the charging control signals to the master charging pile and the one or more slave charging piles for controlling charging of the one or more electric vehicles.

Classes IPC  ?

• B60L 53/67 - Commande de plusieurs stations de charge
• B60L 53/62 - Surveillance et commande des stations de charge en réponse à des paramètres de charge, p. ex. courant, tension ou charge électrique

Abrégé

The present invention provides a bandwidth-boosting phase-noise-cancellation system comprising: a main signal source, an auxiliary signal source, a signal mixer connected to the output of the main signal source and the output of the auxiliary signal source, a frequency multiplier connected to the signal mixer's output, a reference signal source connected to the input of the main signal source, and a fractional divider connected between the output of the main signal source and the input of the auxiliary signal source. The bandwidth boosting system can boost up the overall fractional tuning bandwidth from the main signal source while the main signal source can be optimized for good phase noise and low power consumption with only a narrow tuning range. Moreover, the provided phase correlation and phase noise cancellation technique can help cancel the phase noise from the main signal source and improve the system phase noise even when the desired fractional bandwidth is boosted.

Classes IPC  ?

• H04B 1/66 - Détails des systèmes de transmission, non couverts par l'un des groupes Détails des systèmes de transmission non caractérisés par le milieu utilisé pour la transmission pour réduire la largeur de bande des signauxDétails des systèmes de transmission, non couverts par l'un des groupes Détails des systèmes de transmission non caractérisés par le milieu utilisé pour la transmission pour améliorer l'efficacité de la transmission

Abrégé

Provided herein are methods for reversibly bonding a thermoplastic substrate and a silicone polymer substrate. The reversibly bonded substrates remain bonded to one another in the absence of an external compression force and in the presence of pressures typical of biotechnology applications, but can be cleanly separated from one another without application of a relatively large peeling force. The provided methods involve, among other steps, coating a plasma-treated thermoplastic substrate with a coating solution containing a concentration of APTES that is within a particular range. Also provided are microfluidic devices and sample collection methods involving the disclosed techniques for reversible substrate bonding.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

A system for generating 3D indoor scenes from text input is provided. It includes a user interface, a text processing module, a scene code generator, a layout generation module, an appearance generation module, a NeRF module, and a PeRF module. The user inputs text describing a room, which is processed into scene codes. These codes guide the generation of a 3D layout using oriented bounding boxes, ensuring spatial integrity. The appearance module then creates a visual representation with a panoramic image. The NeRF module constructs a base 3D model, which is refined by the PERF module for enhanced visual coherence.

Classes IPC  ?

• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
• G06F 40/47 - Traduction assistée par ordinateur, p. ex. utilisant des mémoires de traduction
• G06T 17/20 - Description filaire, p. ex. polygonalisation ou tessellation

Abrégé

A computer-implemented method for downscaling an ocean surface wind (OSW). The method comprises: obtaining an input image with a set of wind data, constructing an OSW downscaling model based on a TransUNet architecture; using the OSW downscaling model to generate an output image with a set of resulting wind data according to the input image, and before the OSW downscaling model is used to generate the output image, training the OSW downscaling model according to a plurality of sets of training samples, wherein the OSW downscaling model is trained by optimizing model parameters of the OSW downscaling model in a sense of minimizing a loss function for improving resolution.

Classes IPC  ?

• G06T 3/4046 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement utilisant des réseaux neuronaux
• G01P 5/00 - Mesure de la vitesse des fluides, p. ex. d'un courant atmosphériqueMesure de la vitesse de corps, p. ex. navires, aéronefs, par rapport à des fluides
• G01S 13/95 - Radar ou systèmes analogues, spécialement adaptés pour des applications spécifiques pour la météorologie
• G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
• G06T 3/4007 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement basé sur l’interpolation, p. ex. interpolation bilinéaire
• G06T 11/20 - Traçage à partir d'éléments de base, p. ex. de lignes ou de cercles

Abrégé

A sensor assembly includes a temperature sensing layer, a tangential force sensing layer, and a floating-mountain multi-layer capacitor, where the temperature sensing layer is configured to detect temperature of an object contacting the sensor assembly, the tangential force sensing layer is configured to detect a tangential force applied by the object to the sensor assembly, and the floating-mountain multi-layer capacitor is configured to detect a normal force applied by the object to the sensor assembly.

Classes IPC  ?

• G01L 1/14 - Mesure des forces ou des contraintes, en général en mesurant les variations de la capacité ou de l'inductance des éléments électriques, p. ex. en mesurant les variations de fréquence des oscillateurs électriques
• G01K 7/16 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs
• G01R 33/07 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs galvano-magnétiques des dispositifs à effet Hall
• H05K 1/18 - Circuits imprimés associés structurellement à des composants électriques non imprimés

Abrégé

Remote sensing satellite data services are limited by lack of data processing and analytic capabilities as current solutions rely on manual interventions, which are inefficient, cost prohibitive for large-scale processing, and prone to human errors. A system that utilizes a large language model to understand user intent and provokes corresponding computer vision models fine-tuned with remote sensing imagery datasets, such as open vocabulary object detection and segmentation model with state-of-the-art model architecture, is provided to enable users to extract useful insights by natural language text query. With such revolutionizing visual language model interaction built on a cloud-native platform, the system is able to help customers access satellite data and gain insights faster and easier than ever, and help companies, governments and civil society use satellite imagery to discover actionable insights regarding important phenomena, such as deforestation, agriculture, climate change, biodiversity, and supply chains worldwide.

Classes IPC  ?

• G06F 16/535 - Filtrage basé sur des données supplémentaires, p. ex. sur des profils d'utilisateurs ou de groupes
• G06F 40/40 - Traitement ou traduction du langage naturel

Abrégé

A switchable liquid crystal grating cell, and methods for manufacturing the above. The switchable liquid crystal grating cell comprises a pair of switchable liquid crystal grating parts, each switchable liquid crystal grating part comprises a substrate; a conductive layer on the substrate; and a photoalignment layer with an alignment pattern above the conductive layer on the substrate, the alignment pattern having first and second types of domains, the first type of domain having a first uniform alignment direction, the second type of domain having a second uniform alignment direction that is reoriented at a predetermined angle to the first uniform alignment direction, the predetermined angle is 85°-95°, and a liquid crystal layer sandwiched between the pair of switchable liquid crystal grating parts, wherein an alignment pattern on a top surface is arranged to be shifted relative to the other alignment pattern on a bottom surface.

Classes IPC  ?

• G02F 1/1347 - Disposition de couches ou de cellules à cristaux liquides dans lesquelles un faisceau lumineux est modifié par l'addition des effets de plusieurs couches ou cellules
• G02F 1/1337 - Orientation des molécules des cristaux liquides induite par les caractéristiques de surface, p. ex. par des couches d'alignement
• G02F 1/135 - Cellules à cristaux liquides associées structurellement avec une couche photoconductrice ou ferro-électrique dont les caractéristiques peuvent être optiquement ou électriquement modifiées

Abrégé

A Miller clamping circuit for driving a wide bandgap (WBG) device is provided. The Miller clamping circuit comprises: a semiconductor switching device having high side terminal connected to gate of the WBG device; and low side terminal connected to source of the WBG device; a first diode having anode connected to ground terminal of a driver IC chip; and cathode connected to control terminal of the switching device; a first resistor connected in parallel with the first diode; a second resistor having a first end connected to the ground of the driver IC chip; a second diode having anode connected to the low side terminal of the switching device and cathode connected to a second end of the second resistor; and a third resistor connected in parallel with the second diode. The Miller clamping circuit is configured to suppress a false turn-on and gate-loop oscillation of the WBG device simultaneously.

Classes IPC  ?

• H03K 17/30 - Modifications pour fournir un seuil prédéterminé avant commutation
• H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ

Abrégé

A system includes a measurement module, an industrial I/O expansion module, an SBC module, and a user interface module. The measurement module provides a platform for connecting a PV panel module for current and voltage measurement. The measurement module comprises a voltage sensor, a current sensor, and a MOSFET. The PV panel module and the current sensor are connected in series, and a series combination of the PV panel module and the current sensor is connected in parallel with the voltage sensor as well as the MOSFET. The industrial I/O expansion module is coupled with the measurement module for conversion of analog signals to digital signals. The SBC module obtains current and voltage readings from the measurement module via the industrial I/O expansion module. The user interface module is coupled with the SBC module and provides a user interface, allowing users to operate a measurement process.

Classes IPC  ?

• H02S 50/10 - Tests de dispositifs PV, p. ex. de modules PV ou de cellules PV individuelles
• G01R 19/165 - Indication de ce qu'un courant ou une tension est, soit supérieur ou inférieur à une valeur prédéterminée, soit à l'intérieur ou à l'extérieur d'une plage de valeurs prédéterminée
• H02S 40/30 - Composants électriques

Abrégé

A method and a system for automatic evaluation of online debate arguments are provided. The method includes: defining multiple persona knowledge dimensions; tailor-making a prompt template according to the defined persona knowledge dimensions to generate a persona knowledge eliciting prompt; inputting the persona knowledge eliciting prompt to a pretrained language model to elicit persona knowledge; associating the elicited persona knowledge and the context and argument in the prompt to construct a knowledge-aligned prompt; and utilizing the knowledge-aligned prompt to fine-tune a debate evaluation model to evaluate persuasiveness/impact of the online debate arguments. The present invention can be applied to digital platforms equipped with tools to facilitate virtual discussions, incorporating features such as real-time feedback, interactive interfaces, and enhanced accessibility options to improve the overall debate experience, expand the range of platform participants, and thus make debates easier to understand and more attractive.

Classes IPC  ?

• G06F 40/40 - Traitement ou traduction du langage naturel
• G06F 40/35 - Représentation du discours ou du dialogue

Abrégé

An AI-based event grounding system is provided. The event grounding system includes an input device, an output device, a graphic processing unit (GPU); and a processor. The processor connects the input device, the output device, and the GPU. The event grounding system receives a free-text through the input device, and the processor perform an event grounding to the free-text through the GPU. The GPU performs event acquisition from the free-text using semantic parsing and acquires a plurality of verb-centric events, and performs event abstraction and acquires a plurality of abstract events, and grounds the abstract events to a plurality of anchor events of an event-centric KG, and reasons a subgraph through a reasoning model, and the subgraph includes the abstract events and the anchor events. The GPU generates a prediction based on the reasoning and provide the prediction through the processor and the output device.

Classes IPC  ?

• G06F 40/30 - Analyse sémantique
• G06F 40/205 - Analyse syntaxique
• G06F 40/253 - Analyse grammaticaleCorrigé du style
• G06F 40/284 - Analyse lexicale, p. ex. segmentation en unités ou cooccurrence
• G06N 5/04 - Modèles d’inférence ou de raisonnement

Abrégé

A light emitting device (LED) comprises a substrate, an anode layer disposed on the substrate, a hole injection layer disposed on the anode layer, a hole transport layer disposed on the hole injection layer, an emitting layer disposed on the hole transport layer, an electron transport layer disposed on the emitting layer, and a cathode layer disposed on the electron transport layer. At least one of the anode layer and the cathode layer is transparent. The emitting layer comprises a mixture of luminescent nanoparticles and an insulating material.

Classes IPC  ?

• H10K 50/115 - OLED ou diodes électroluminescentes polymères [PLED] caractérisées par les couches électroluminescentes [EL] comprenant des nanostructures inorganiques actives, p. ex. des points quantiques luminescents
• B82Y 20/00 - Nano-optique, p. ex. optique quantique ou cristaux photoniques
• H10K 50/18 - Couches de blocage des porteurs de charge
• H10K 85/10 - Polymères ou oligomères organiques

Abrégé

A cascode semiconductor device comprise a normally-on high-voltage (HV) silicon carbide (SiC) junction field-effect transistor (JFET), a normally-off low-voltage (LV) gallium nitride (GaN) high-electron-mobility transistor (HEMT) and a clamping circuit. The SiC JFET has a first gate terminal, a first drain terminal and a first source terminal. The GaN HEMT has a second gate terminal, a second drain terminal and a second source terminal. The second drain terminal is connected to the first source terminal. The second source terminal is connected to the first gate terminal. The clamping circuit is connected between the second drain terminal and the second gate terminal and has a clamping voltage. The clamping voltage is greater than a magnitude of a threshold voltage of the SiC JFET and smaller than a reverse gate voltage limit of the SiC JFET.

Classes IPC  ?

• H01L 27/088 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des éléments de circuit passif intégrés avec au moins une barrière de potentiel ou une barrière de surface le substrat étant un corps semi-conducteur comprenant uniquement des composants semi-conducteurs d'un seul type comprenant uniquement des composants à effet de champ les composants étant des transistors à effet de champ à porte isolée
• H01L 27/06 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des éléments de circuit passif intégrés avec au moins une barrière de potentiel ou une barrière de surface le substrat étant un corps semi-conducteur comprenant une pluralité de composants individuels dans une configuration non répétitive
• H03K 17/0412 - Modifications pour accélérer la commutation sans réaction du circuit de sortie vers le circuit de commande par des dispositions prises dans le circuit de commande
• H03K 17/0814 - Modifications pour protéger le circuit de commutation contre la surintensité ou la surtension sans réaction du circuit de sortie vers le circuit de commande par des dispositions prises dans le circuit de sortie
• H03K 17/16 - Modifications pour éliminer les tensions ou courants parasites

Abrégé

A system using global and local-aware denoising framework for commonsense knowledge graph noise detection is provided. The system includes an input receiver, a triple encoder, a global noise detector, a local noise detector, and a comprehensive evaluation scorer. The triple encoder receives the CSKG information from the input receiver and extract semantic information from free-text formatted nodes in the CSKG information, so as to obtain structured triples. The global noise detector identifies high-frequency patterns through rule mining and uses a rule encoder to generalize learned rules and guide noise detection. The local noise detector utilizes the structured triples output by the triple encoder to aggregate neighboring triple information around both the head and tail nodes via graph networks. The comprehensive evaluation scorer provides a comprehensive score based on global noise detection and local noise detection, so as to indicate a noise level for the CSKG information.

Classes IPC  ?

• G06F 40/157 - Transformation utilisant des dictionnaires ou des tableaux
• G06F 40/30 - Analyse sémantique

Abrégé

Provided herein is a novel method named Knowledge-Constrained Tree Search Decoding (KCTS) is provided, which is a first discriminator-guided constrained decoding approach to knowledge-grounded generation. The KCTS method also employs a Monte-Carlo Tree Search decoding (MCTS) instead of conventional LM decoding methods, which re-orders each token's importance based on the estimated future faithfulness starting from that token with multiple simulations. Coupled with a novel token-level hallucination detection method, RIPA (Reward Inflection Point Approximation), trained to predict the starting point of the hallucinating token, enabling effective adaptation of the knowledge classifier defined on the sequence level to the token level, this novel method is able to greatly mitigate hallucination problems of LLMs without the need of fine-tuning, thereby preventing the incurrence of high computational costs.

Classes IPC  ?

• G06F 40/284 - Analyse lexicale, p. ex. segmentation en unités ou cooccurrence

Abrégé

Provided herein is a method of improved commonsense knowledge bases reasoning through constraint-based prompting. A novel dual-module constraint-based prompt engineering system named ConstraintChecker is involved, which employs a first rule-based module to produce a list of constraints and a second zero-shot learning module to check whether the knowledge instance satisfies all constraints. The acquired constraint-checking result is then aggregated with the output of the main prompting backbone to produce the final output. This present method is more effective in commonsense knowledge bases reasoning then that by employing the prompting backbone alone, and also significantly reduces computational costs.

Classes IPC  ?

• G06N 5/04 - Modèles d’inférence ou de raisonnement

Abrégé

The subject invention pertains to a long-term antigen depot that can bypass FBR and engage DCs to mature and migrate to lymph nodes to activate antigen-specific T-cell activations. Leveraging on the immunomodulatory properties of exogenous polysaccharides and the anti-fouling characteristics of zwitterionic phosphorylcholine (PC) polymer, the invention features a PC functionalized dextran (PCDX) hydrogel for long-term antigen delivery. PCDX in both injectable scaffold and microparticles (MPs) forms effectively evades FBR and provides slow release of antigens resulting in local enrichment of CD11c+ DCs at the MPs injection sites. DC cultured on PCDX exhibits strong immunogenic activation with high CD86, CD40, MHC-I/peptide complex. PCDX also generates DC with propensity in migration to lymph nodes, as well as antigen presentation to trigger both CD4+ and CD8+ arms of T-cell responses. Besides cellular responses, PCDX can also induce potent humoral responses, with high levels of antigen specific IgG1 and IgG2a by day 28. Overall, PCDX provides long-term delivery of antigens for vaccine development.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/06 - OnguentsExcipients pour ceux-ci
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61K 39/385 - Haptènes ou antigènes, liés à des supports
• A61P 37/04 - Immunostimulants
• C08B 37/02 - DextraneSes dérivés

Abrégé

A tetrachromatic perovskite image sensor includes a quartz layer, two perovskite p-i-n-i-p components, and two optical transparent electrodes. The first perovskite p-i-n-i-p component, on one side of the quartz layer, detects ultraviolet and blue light, with two photodetection layers corresponding to detection to ultraviolet and blue wavelength intervals. The second component, on the opposite side, detects green and red light, with layers for detecting green and red wavelength intervals. Optical transparent electrodes on both sides of the quartz layer apply bias collectively to both perovskite p-i-n-i-p components.

Classes IPC  ?

• H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
• H10K 39/32 - Capteurs d'images organiques

Abrégé

A lipophilic anchor includes a conjugation domain linked via a linker domain to an anchor domain having a plurality of hydrophobic tails. This lipophilic anchor allows deposition of at least one lipophilic target molecule with affinity for the anchor domain on a hydrophilic surface conjugated to the conjugation domain. The lipophilic target molecule coated hydrophilic substrate has the conjugation domain of the lipophilic anchor bound to the hydrophilic surface of a substrate and lipophilic target molecules are non-covalently bound to the anchor domain.

Classes IPC  ?

• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
• G01N 33/92 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des lipides, p. ex. le cholestérol

Abrégé

Europium doped tin perovskites useful in the fabrication of optoelectronic devices exhibiting improved stability and high-power conversion efficiencies and perovskite precursor solutions used to prepare the europium doped tin perovskite, wherein the europium doped tin perovskite can be represented by Formula 1: Europium doped tin perovskites useful in the fabrication of optoelectronic devices exhibiting improved stability and high-power conversion efficiencies and perovskite precursor solutions used to prepare the europium doped tin perovskite, wherein the europium doped tin perovskite can be represented by Formula 1: (A+)(Sn2+)(X−)3·m[(Eu2+)(Y−)2]  1 wherein m is 0.001-0.05; X− for each instance is independently F−, Cl−, Br−, or I−; Y− for each instance is independently F−, Cl−, Br−, or I−; and A+ is Cs+, Rb+, CH3NH3+, CH3CH2NH3+, H(C═NH2)NH2+, Me(C═NH2)NH2+, or a mixture thereof.

Classes IPC  ?

• H10K 71/30 - Dopage de couches actives, p. ex. de couches de transport d'électrons
• C07F 19/00 - Composés métalliques couverts par plus d'un des groupes principaux
• H10K 30/30 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des hétérojonctions de masse, p. ex. des réseaux interpénétrés de domaines de matériaux donneurs et accepteurs
• H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
• H10K 30/50 - Dispositifs photovoltaïques [PV]
• H10K 71/15 - Dépôt d'une matière active organique en utilisant un dépôt liquide, p. ex. revêtement par centrifugation caractérisé par le solvant utilisé
• H10K 85/50 - Pérovskites organiquesPérovskites hybrides organiques-inorganiques [HOIP], p. ex. CH3NH3PbI3

Abrégé

Single atom catalysts (SACs) are efficient electrocatalysts for catalyzing the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in lithium-oxygen batteries (LOBs). Our method is to study the origin of reactivity for a series of 17 transition metals supported on nitrogen-doped graphene, denoted SACs using Quantum Mechanics methods. Based on Gibbs free energy calculations, Zn-SAC performs the highest electrochemical activity among 17 SACs investigated. Machine learning (ML) is developed an intrinsic descriptor Φ, that correlates the catalytic activity with electronic and chemical properties of the catalytic centers at the M-N4 active site on graphene surface. A linear relationship between Φ and the catalytic activity that provides guidance for designing efficient SACs for electrocatalysis in LOBs. Zn-SAC is synthesized through chemical vapor deposition (CVD) process, which shows more stable cyclability and exhibits smaller reaction overpotentials, verifying the simulation results.

Classes IPC  ?

• H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
• H01M 4/04 - Procédés de fabrication en général
• H01M 10/052 - Accumulateurs au lithium
• H01M 10/0568 - Matériaux liquides caracterisés par les solutés
• H01M 10/0569 - Matériaux liquides caracterisés par les solvants

Abrégé

Provided is the new compositions and methods useful for the treatment, prevention, and potential cure of a genetic disease, such as familial Alzheimer's Disease, by disrupting the genomic sequence harboring one or more SNPs that are of high prevalence in a population but no relevance to the particular disease except for their genomic locations being in the same gene exon as a disease-relevant allele and upstream from such disease-relevant allele present in the genome of a treatment recipient.

Classes IPC  ?

• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
• C12N 15/90 - Introduction stable d'ADN étranger dans le chromosome
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

Provided herein is a thermal-managed photovoltaic glass glazing panel comprising a photovoltaic glazing a thermal insulation layer coated on the front surface of the photovoltaic glazing, wherein the thermal insulation layer includes a passive radiative cooling coating material; and a sound and thermal insulation module, wherein the sound and thermal insulation module comprises vacuum glazing, hollow glazing or a combination thereof, adhered to the rear side of the photovoltaic glazing. The photovoltaic glazing module of the present invention not only optimizes solar power generation through specific thermal management designs, but also minimizes both heat transfer and noise intrusion to the interior of the building, maintaining a quiet and stable internal ambient environment, minimizing impacts from the external environment.

Classes IPC  ?

• H02S 20/26 - Matériaux de construction intégrés avec modules PV, p. ex. éléments de façade
• H02S 30/00 - Détails structurels des modules photovoltaïques [PV] autres que ceux qui concernent la conversion de la lumière

Abrégé

The present disclosure relates generally to a method, apparatus, and system for predicting a pulmonary arterial hypertension condition of a subject, the method comprising: measuring, by a processor, a morphological feature of a region of a heart of the subject from a plurality of echocardiogram videos, each of the plurality of echocardiogram videos showing the heart at a different viewing angle, the morphological feature relating to the pulmonary arterial hypertension condition; and generating, by the processor, a prediction score representing a likelihood of the subject having the pulmonary arterial hypertension condition from the morphological feature.

Classes IPC  ?

• A61B 8/08 - Applications cliniques
• A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin

Abrégé

A method using AI models to generate patterns or images on a pastry is provided. The method at least includes steps as follows: providing a UI module for user input of keywords and descriptions; generating black and white vector-style images based on this input using an AI-based image module; processing the 2D image into digital instructions via an image-transformer module; sending these instructions to a laser patterning module; and using the laser patterning module to apply the pattern to the cookie's surface.

Classes IPC  ?

• G05B 19/4099 - Usinage de surface ou de courbe, fabrication d'objets en trois dimensions 3D, p. ex. fabrication assistée par ordinateur

Abrégé

A method for determining a shape of an object in an image, comprising: generating, for each of a first plurality of images, a first plurality of nodes based on a first plurality of features extracted from each of the first plurality of images, the first plurality of features associated with a shape of an object in the first plurality of images; determining, for each of the first plurality of nodes, one or more other nodes based on historical data indicating a previous position and a time associated with the previous position of each of the first plurality of nodes; and determining the shape of the object for each of the first plurality of images based on the one or more other nodes.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• G06T 7/11 - Découpage basé sur les zones

Abrégé

A polymer-based composite fiber includes a matrix including one or more polymers, a plurality of voids formed in the matrix, and a plurality of solid particles, each particle of the plurality of solid particles being disposed in a respective void of the plurality of voids. The fiber may have an aspect ratio of at least 10, the fiber aspect ratio being defined as the length of the fiber divided by the diameter of the fiber. Each void of the plurality of voids may have a respective long axis, each long axis being a line that extends through a longest dimension of the void, and each long axis may extend in a direction parallel to the length of the fiber.

Classes IPC  ?

• D01F 1/10 - Autres agents modifiant les propriétés de ces filaments
• D01F 6/62 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de produits d'homopolycondensation à partir de polyesters
• D03D 15/33 - Fibres ultrafines, p. ex. microfibres ou nanofibres
• D03D 15/547 - Tissus caractérisés par la matière, la structure ou les propriétés des fibres, des filaments, des filés, des fils ou des autres éléments utilisés en chaîne ou en trame caractérisés par les propriétés des filés ou des fils à fonctions optiques autres que la couleur, p. ex. comportant des fibres émettrices de lumière
• D03D 15/573 - Résistance à l’étirement
• D04B 1/16 - Autres tricots ou articles caractérisés principalement par l'emploi de matières spéciales pour le fil fils synthétiques
• D04B 21/16 - Tissus caractérisés par l'incorporation par tricotage de fils de renforcement, de fils de liage ou de fils décoratifs, dans un ou plusieurs fils, nappe ou couche de tissuTricots incorporant de petits éléments auxiliaires, p. ex. à des fins décoratives incorporant des fils synthétiques

Abrégé

Re(V) alkylidyne-based catalytic systems for alkyne metathesis reactions capable of effecting alkyne metathesis, such as homo- and cross-metathesis of alkynes or diynes, ring closing metathesis and ring-opening metathesis, at room temperature to moderate temperatures. The catalysts are stable to air and moisture and tolerate a variety of functional groups in substrates and can be readily prepared on a large scale, and thus are practical catalytic systems of Re(V) alkylidynes.

Classes IPC  ?

• B01J 31/24 - Phosphines
• B01J 31/22 - Complexes organiques
• C07C 29/36 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone ne faisant pas partie d'un cycle aromatique à six chaînons par des réactions augmentant le nombre d'atomes de carbone avec formation de groupes hydroxyle, ces groupes pouvant être produits par l'intermédiaire de dérivés de groupes hydroxyle, p. ex. du dérivé O-métal
• C07C 45/68 - Préparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par des réactions ne créant pas de groupe C=O par isomérisationPréparation de composés comportant des groupes C=O liés uniquement à des atomes de carbone ou d'hydrogènePréparation des chélates de ces composés par des réactions ne créant pas de groupe C=O par modification de la taille du squelette carboné par augmentation du nombre d'atomes de carbone
• C07D 211/06 - Composés hétérocycliques contenant des cycles pyridiques hydrogénés, non condensés avec d'autres cycles avec uniquement des atomes d'hydrogène et de carbone liés directement à l'atome d'azote du cycle ne comportant pas de liaison double entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques
• C07D 225/02 - Composés hétérocycliques contenant des cycles de plus de sept chaînons ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle non condensés avec d'autres cycles
• C07D 321/00 - Composés hétérocycliques contenant des cycles comportant deux atomes d'oxygène comme uniques hétéro-atomes du cycle, non prévus par les groupes
• C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles

Abrégé

A phased-array transmitter system includes a plurality of signal paths and a power amplifier. Each of the signal paths comprises: a phase-shifter configured to generate a phase-shifted signal; a first mixer configured to mix the phase-shifted signal with a baseband signal to generate a first mixed signal; a variable gain amplifier (VGA) configured to perform phase-invariant gain-controlled amplification on the first mixed signal; a second mixer configured to mix the amplified first mixed signal with a radiofrequency local oscillator (RFLO) signal to generate a radiofrequency (RF) signal; and a power amplifier configured to amplify the RF signal and feed the amplified RF signal to an antenna.

Classes IPC  ?

• H04B 1/403 - Circuits utilisant le même oscillateur pour générer à la fois la fréquence de l’émetteur et la fréquence de l’oscillateur local du récepteur
• H04B 1/04 - Circuits

Abrégé

A method for a photon induced conductive material deposition on a substrate is provided. The method includes steps as follows: preparing a first solution comprising metalate, metal ions, or combinations thereof; preparing a first suspension comprising nanoparticles, a light sensitive reducing agent, an electron providing solvent, or combinations thereof; mixing the first solution and the first suspension to form a first reagent on a first substrate; and emitting a light beam provided by a light source and focusing the same onto the first reagent kept on a first region of the first substrate, so as to form a mechanically rigid conductive deposition in contact with the first substrate in a focus point of the light source, wherein the first substrate has a second region exposed to surrounding gas or an air environment.

Classes IPC  ?

• H01L 21/288 - Dépôt de matériaux conducteurs ou isolants pour les électrodes à partir d'un liquide, p. ex. dépôt électrolytique
• H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
• H01L 29/24 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des matériaux semi-conducteurs inorganiques non couverts par les groupes , ,  ou
• H01L 29/45 - Electrodes à contact ohmique
• H01L 29/772 - Transistors à effet de champ

Abrégé

An apparatus includes an optical writing module and an optical characterization module. The optical writing module is configured to emit a laser beam and guide the laser beam toward a substrate. The optical characterization module is optically coupled with the optical writing module such that the optical writing module and the optical characterization module share the same optical path. The optical writing module is configured to emitting an observation light beam toward the substrate. The optical characterization module is further configured to determine whether a mixture of solution and suspension is in contact with the substrate. When the mixture is determined in contact with the substrate, the laser beam is enabled to irradiate the mixture near a surface of the substrate, so as to form a mechanically rigid material deposition in contact with the substrate.

Classes IPC  ?

• B23K 26/03 - Observation, p. ex. surveillance de la pièce à travailler
• B23K 26/06 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples
• B23K 26/14 - Travail par rayon laser, p. ex. soudage, découpage ou perçage en utilisant un écoulement de fluide, p. ex. un jet de gaz, associé au faisceau laserBuses à cet effet
• B81C 1/00 - Fabrication ou traitement de dispositifs ou de systèmes dans ou sur un substrat

Abrégé

A method for preparing a composite construction material, the method including: combining plastic waste and construction waste, such as construction debris, crushed rock, stone, concrete rubbles, soil, or a mixture thereof, thereby forming a waste mixture; and curing the waste mixture under oxygen-free conditions thereby melting or softening at least a portion of the plastic waste and forming the composite construction material.

Classes IPC  ?

• B29B 17/00 - Récupération de matières plastiques ou d'autres constituants des déchets contenant des matières plastiques
• B29K 23/00 - Utilisation de polyalcènes comme matière de moulage
• B29K 105/26 - Résidus
• B29K 509/00 - Utilisation de matériaux inorganiques non prévus dans les groupes comme matière de remplissage
• B29K 509/06 - Béton
• F28F 13/18 - Dispositions pour modifier le transfert de chaleur, p. ex. accroissement, diminution par application de revêtements, p. ex. absorbant les radiations ou les réfléchissantDispositions pour modifier le transfert de chaleur, p. ex. accroissement, diminution par application d'un traitement de surface, p. ex. un polissage

Abrégé

Techniques are described for augmenting chest X-ray (CXR) images with synthetic lesions using a lesion-aware machine learning framework in association with optimizing thoracic disease detection models. In an example, a system can comprise a lesion augmentation component that generates synthetic lesion images comprising synthetic lesion image data objects integrated on or within medical images using lesion generator, trained to generate the synthetic lesion image data objects, and tailor the synthetic lesion image data objects to account for different types of lesions and different anatomical locations of the lesions. The system can further comprise a training component that trains a lesion detector using the synthetic lesion images. The training component can further perform an alternate training strategy to integrate the training of the lesion generator and the detector for mutual boosting.

Classes IPC  ?

• G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”

Abrégé

An aligned and multichannel peripheral nerve conduit, including Polyvinyl alcohol (PVA) and graphene oxide (GO) with aligned and multichannel design for peripheral nerve repair. 3D printing technology with assembly is utilized to make a specific mold to get a multichannel design to mimic natural peripheral nerves. Directional freeze casting is used to form an aligned PVA/GO hydrogel structure to guide cell growth.

Classes IPC  ?

• A61L 27/08 - Carbone
• B82Y 5/00 - Nanobiotechnologie ou nanomédecine, p. ex. génie protéique ou administration de médicaments
• C01B 32/194 - Post-traitement
• C01B 32/198 - Oxyde de graphène

Abrégé

A passive on-chip optical long-pass filter for removing residual pump photons at short wavelengths after nonlinear generation of photons. A thin layer (<100 nm) of amorphous or poly-crystalline silicon is deposited onto a section of a waveguide to absorb light with a wavelength shorter than the silicon bandgap wavelength of ˜1.1 μm, while the nonlinearly generated light in longer wavelengths than the silicon bandgap wavelength propagates in the waveguide with a negligible absorption loss. The filter is applicable to attain an on-chip optical pump light rejection ratio exceeding 120 dB for nonlinear and quantum photonic chips. The filter is conceptually simple to design and can be fabricated by a CMOS process with potentially a high wafer-level scalability and manufacturability at a low cost. The filter can be realized in various integrated photonic platforms, including silicon carbide, silicon nitride, lithium niobate and aluminum nitride.

Classes IPC  ?

• G02B 6/122 - Éléments optiques de base, p. ex. voies de guidage de la lumière
• G02B 6/12 - Guides de lumièreDétails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p. ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
• G02B 6/125 - Courbures, branchements ou intersections
• H01L 31/0232 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails - Détails Éléments ou dispositions optiques associés au dispositif

Abrégé

Compositions and methods comprising artificial poly (A) sequences having at least one cytosine and at least one uridine and/or guanosine are provided.

Classes IPC  ?

• C12N 15/67 - Méthodes générales pour favoriser l'expression

Abrégé

A system is provided for training a neural network model. The system comprises one or more image acquisition devices, configured to obtain volumetric image data; and one or more processors, configured to: generate images of a plurality of views, which comprise a global complete view and one or more masked views; generate, by a Global-Local Masked AutoEncoder (GL-MAE) encoder system, representations corresponding to the global complete view and the one or more masked views; generating one or more reconstructed images corresponding to the one or more masked views; evaluating in a shared representation space, consistency between the representations of the global complete view and the one or more masked views; computing one or more losses based on the one or more reconstructed images and the results from the consistency evaluation; and updating one or more parameters in the neural network model based on the one or more losses.

Classes IPC  ?

• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
• G06T 3/40 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement
• G06T 7/10 - DécoupageDétection de bords
• G06T 9/00 - Codage d'image
• G06T 15/00 - Rendu d'images tridimensionnelles [3D]
• G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]

Abrégé

This disclosure provides methods and apparatus with regard to ultrathin metal-organic frameworks for the application of carbon dioxide reduction. In one aspect, a method of preparing metal-organic frameworks by copper and second metal ion clusters coordinating with metalloporphyrinic linkers. In the other aspect, the metal-organic frameworks are coated on the working electrode as electrocatalysts for carbon dioxide reduction are presented.

Classes IPC  ?

• C25B 11/085 - Composé organique
• C25B 3/26 - Réduction du dioxyde de carbone
• C25B 9/19 - Cellules comprenant des électrodes fixes de dimensions stablesAssemblages de leurs éléments de structure avec des diaphragmes
• C25B 11/02 - ÉlectrodesLeur fabrication non prévue ailleurs caractérisées par la configuration ou la forme
• C25B 11/042 - Électrodes à base d’un seul matériau
• C25B 11/052 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
• C25B 11/065 - Carbone
• C25B 13/08 - DiaphragmesÉléments d'espacement caractérisés par le matériau à base de matériaux organiques
• C25B 15/08 - Alimentation ou vidange des réactifs ou des électrolytesRégénération des électrolytes

Abrégé

A machine learning (ML) workflow for virtual staining and computational pathology based on a label-free tissue sample is provided to avoid a laborious and time-consuming procedure of pathologist-based interpretation of formalin-fixed and paraffin-embedded histology. A virtual-staining ML model translates a label-free autofluorescence (AF) whole slide image (WSI) of the tissue sample into a virtual hematoxylin and eosin (H&E) -stained WSI, which is further transformed into a WSI virtually stained with a special stain by a stain-transformation ML model. Each of the ML models can be realized as a U-Frame model. A multiple instance learning (MIL) network with attention-based pooling can be applied to the virtual H&E-stained WSI or AF WSI to provide fast and accurate tumor diagnosis. Furthermore, the attention-based MIL network can be configured as a clustering-constrained-attention multiple instance learning (CLAM) model for providing multiclass tumor subtyping, or even multiclass disease typing, in diagnosis of the tissue sample.

Classes IPC  ?

• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie

Abrégé

The present invention provides a rechargeable alkaline battery with enhanced cycling stability and coulombic efficiency. The battery includes a cathode prepared with a cathode material and connected to a first terminal, an anode prepared with an anode material and connected to a second terminal, a hydroxide electrolyte with a higher concentration, and at least one porous separator positioned between the anode and the cathode. The hydroxide electrolyte inhibits hydrogen evolution from approximately 20% to less than 5% of an overall reaction. When cycled at 40% DOD under charging and discharging at 15 mA/cmZn2, the rechargeable alkaline battery exhibits a cycling stability with a capacity retention of >80% after 290 cycles.

Classes IPC  ?

• H01M 10/26 - Emploi de matériaux spécifiés comme électrolytes
• H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
• H01M 4/24 - Électrodes pour accumulateurs alcalins
• H01M 4/32 - Électrodes en oxyde ou en hydroxyde de nickel
• H01M 50/491 - Porosité
• H01M 50/497 - Conductivité ionique

Abrégé

This invention refers to a liquid-based micro thermal convective accelerometer (MTCA) optimized using a compact model based on the Rayleigh number (Ra). The MTCA is fabricated using CMOS MEMS technology. To ensure water resistance, an isolation layer such as a waterproof cover, exemplified by the conformal Parylene C coating, is employed. The device's performance is assessed in terms of sensitivity, response time, and noise. Theoretical and experimental findings establish that fluids with higher Ra numbers yield improved MTCA performance. Ra-based model showed its advantage to make a more accurate prediction than the simple linear model to select suitable fluid to enhance the sensitivity and balance the linear range of the device. In some cases, the liquid of MTCA can be selected as alcohol, and an alcohol-based MTCA was achieved with a two-order-of magnitude increase in sensitivity and one-order-of-magnitude decrease in the limit of detection compared with the air-based MTCA.

Classes IPC  ?

• G01P 15/00 - Mesure de l'accélérationMesure de la décélérationMesure des chocs, c.-à-d. d'une variation brusque de l'accélération
• G01K 7/22 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs l'élément étant une résistance non linéaire, p. ex. une thermistance

Abrégé

An apparatus comprises a body made of a deformable material, and a plurality of protrusions movably attached to an inner surface of the body, each of the plurality of protrusions extending in a direction from the inner surface towards a center of the body, and configured to be moveable in the direction in response to a deformation of the body.

Classes IPC  ?

• G01L 1/24 - Mesure des forces ou des contraintes, en général en mesurant les variations des propriétés optiques du matériau quand il est soumis à une contrainte, p. ex. par l'analyse des contraintes par photo-élasticité
• G01B 11/16 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la déformation dans un solide, p. ex. indicateur optique de déformation

Abrégé

A heat spreader composed of a hexagonal boron carbon nitride (hBCN) thin film, can be a major solution for the ever-increasing problem of overheating electronic devices. This heat spreader can dissipate heat away from hotspots on electronic devices, unlocking additional processing power. Our method is able to effectively tune the thermal and electrical conductivity of our films by modulating the carbon content of the precursor used in a chemical vapor deposition (CVD) process. Using this method, we can generate a heat spreader that is electrically insulative, so it will not have the potential to create shorts, like graphene and metals. Additionally, we can maximize the thermal conductivity, obtaining a value of 460±149 W/m·K, which rivals or even surpasses hexagonal boron nitride (hBN). As our precursor material is 10 times cheaper than the most common hBN precursor, this is an economical alternative to hBN for heat spreader applications.

Classes IPC  ?

• H05K 7/20 - Modifications en vue de faciliter la réfrigération, l'aération ou le chauffage
• C01B 21/064 - Composés binaires de l'azote avec les métaux, le silicium ou le bore avec le bore
• C09K 5/14 - Substances solides, p. ex. pulvérulentes ou granuleuses
• C23C 16/36 - Carbo-nitrures

Abrégé

This system presents a comprehensive approach for detecting protein-protein interactions and exploring protein structures. It encompasses various components, including a receptacle for receiving cross-linked precursor peptides, a mass spectrometer for generating MS1 and MS2 spectra, and modules for precursor mass refinement, MS2 spectrum scoring, protein score database construction, and feedback mechanism processing. Through the integration of these elements, the system facilitates the identification of peptide interactions and protein structures, leveraging a cross-linking dataset obtained from proteins cross-linked with cleavable or non-cleavable crosslinking reagents.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules

Abrégé

A method and an apparatus for decoding channel codes received from a noisy communication channel are provided. The method comprises: demodulating the received channel codes to obtain a demodulated data vector; and decoding, using a compute-in-memory (CIM), the demodulated data vector to obtain one or more candidate output codewords, the demodulated data vector is decoded with a guessing random additive noise decoding (GRAND) algorithm to obtain a candidate output codeword. By leveraging CIM technique for GRAND implementation, due to the intrinsic small size of memory cells relative to logic gates, the integration of storing and computing operations (e.g. multiply-and-accumulate (MAC) operation on the input vector with the weight matrix) in memory cells enables concurrently evaluating a multitude error patterns, therefore substantially reduce the worst-case latency of GRAND hardware implementation.

Classes IPC  ?

• G06F 11/36 - Prévention d'erreurs par analyse, par débogage ou par test de logiciel

Abrégé

Translational rapid ultraviolet-excited sectioning tomography (TRUST) applies ultraviolet (UV) excitation to a sample and images fluorescence and autofluorescence emission for tomographically imaging the sample. Deep-learning neural networks are used to achieve higher imaging speed and imaging resolution. In one use, fluorescence images acquired with relatively low imaging resolution can be transformed into high-resolution images through the first conditional generative adversarial network (cGAN), a super-resolution neural network (e.g., ESRGAN), which is also helpful for reducing the image scanning time. In another use, the second cGAN, such as Pix2Pix, is used to realize virtual optical sectioning to enhance the axial resolution of the imaging system. Compared to the conventional pattern illumination methods (e.g., HiLo microscopy), which need at least two shots for each field of view, the imaging speed is also times higher because only one shot under the uniform-illumination condition of UV irradiation is required.

Classes IPC  ?

• G06T 3/4046 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement utilisant des réseaux neuronaux
• G06T 7/00 - Analyse d'image

Abrégé

A collaborative nexus device for solving climate change mitigation and water sustainability. The device comprises a connecting port and a processor. The processor obtains at least one task data from a plurality of request ends and at least one candidate data from a plurality of bidding ends through the connecting port. The processor matches a plurality of items related to climate change mitigation and water sustainability of the candidate data with at least one of the task data. The processor providing a collaborative contract to the request end corresponded to the matched task data and the bidding end corresponded to the matched candidate data. The processor provides a collaborative space to both the matched request end and the matched bidding end. A system for collaborative nexus is also provided.

Classes IPC  ?

• G06Q 50/00 - Technologies de l’information et de la communication [TIC] spécialement adaptées à la mise en œuvre des procédés d’affaires d’un secteur particulier d’activité économique, p. ex. aux services d’utilité publique ou au tourisme
• G01W 1/00 - Météorologie

Abrégé

Systems and methods for multi-spectral and label-free autofluoresence histochemical instant virtual staining are provided. The system includes a sample holder, one or more light sources, an imaging device, and a processor means. The sample holder is configured to secure a sample on a movable structure that is movable in at least two dimensions. The one or more light sources are configured to obliquely illuminate the sample for excitation of the sample. The imaging device is configured to capture images of the sample and the processing means is configured to receive the images of the sample and process the images in accordance with a histochemical virtual staining process. The images include an autofluorescence image and the histochemical virtual staining process includes subdividing the autofluorescence image into a plurality of regions, global sampling a selected region of the autofluorescence image, and classifying the autofluorescence image as one of a plurality of real image classifications or a fake image classification.

Classes IPC  ?

• G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
• G01N 1/30 - TeintureImprégnation
• G01N 1/31 - Appareils à cet effet
• G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
• G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
• G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”

Abrégé

Provided is a recombinantly produced fusion protein that includes an optically responsive element fused to a downstream signaling element derived from an active domain of a signaling molecule, such as the intracellular domain of a receptor protein, and is therefore capable of triggering the signal transduction cascade by light exposure rather than the native activating event to the signaling molecule, such as the binding of a ligand to the receptor. The nucleic acid encoding the fusion protein and the host cells containing the fusion protein or the nucleic acid are also provided. Further provided are methods of using light exposure to achieve desirable downstream effects of a signal transduction pathway normally mediated by the signaling molecule, for example, in the promotion optic neuronal cell proliferation, survival, and/or regeneration.

Classes IPC  ?

• C07K 19/00 - Peptides hybrides
• C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
• C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire

Abrégé

Microfluidic devices having microwell arrays that enable scalable and parallel droplet multi-step reactions and associated methods for implementing reactions in paired microwells of two different sizes via numerous repeating units of trapping wells as well as sequentially collecting and merging droplets. Droplets that contain the desired species or reagents for reactions are input onto the microfluidic platform. Each well is set up to initially capture one larger droplet, then repeatedly capture smaller ones, followed by merging of larger and smaller droplets. In some embodiments, this action is facilitated by tilting the chip. In some implementations, larger droplets merge three batches of paired, smaller droplets with various needed components in succession while conducting incubation in between the merge and loading. In alternative implementations, each trapping well has two or more active capture sites that merge multiplexed smaller droplets simultaneously and merge more than once.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions

Abrégé

A method useful for preparing butenolides in high yield, the method comprising: contacting an aldehyde, malonic acid, and an organic base thereby forming a Knoevenagel condensation product; and contacting the Knoevenagel condensation product, an oxidant, a metal halide, and optionally an inorganic base thereby forming the butenolide.

Classes IPC  ?

• C07D 307/33 - Atomes d'oxygène en position 2, l'atome d'oxygène étant sous la forme céto ou énol non substituée

Abrégé

The present invention belongs to the field of nanomedicine, and provides a DC biomimetic membrane nanoparticle loaded with an NIR-II AIE dye, a preparation method therefor and use thereof. The DC biomimetic membrane nanoparticle loaded with the NIR-II AIE dye comprises a DC membrane and an NIR-II AIE dye loaded therein, wherein the NIR-II AIE dye has photothermal characteristics. The DC biomimetic membrane nanoparticle loaded with the NIR-II AIE dye provided by the present invention not only solves the problem that the NIR-II AIE dye is poor in water solubility and limited in fluorescence imaging, but also increases the enrichment efficiency of the NIR-II AIE dye coated by the DC membrane at a tumor site and successfully activates the activity of T cells in vivo.

Classes IPC  ?

• A61K 49/00 - Préparations pour examen in vivo
• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
• A61P 35/00 - Agents anticancéreux

Abrégé

A pinhole compound eye (PHCE) system includes: a pinhole array comprising a plurality of pinholes, wherein the pinhole array is configured to receive light from varying incident angles; and a detector array comprising a plurality of nanowires, wherein the detector array is positioned at a concave surface of the pinhole array and is configured to detect light passing through the pinhole array.

Classes IPC  ?

• H01L 27/146 - Structures de capteurs d'images
• B33Y 80/00 - Produits obtenus par fabrication additive
• G02B 5/20 - Filtres
• H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
• H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives

Abrégé

Provided are new compositions and methods useful for the treatment, prevention, and potential cure of Alzheimer's Disease by disrupting the genomic locus of IL1LR1 gene including rs1921622 and/or other 574 sST2-associated genomic sites and/or 3′-UTR of sST2 gene/transcript.

Classes IPC  ?

• C12N 9/22 - Ribonucléases
• A61K 31/7105 - Acides ribonucléiques naturels, c.-à-d. contenant uniquement des riboses liés à l'adénine, la guanine, la cytosine ou l'uracile et ayant des liaisons 3'-5' phosphodiester
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens

Abrégé

The subject invention pertains to a method for promoting axon regeneration in a subject, including those with central nervous system (CNS) injury, by activation of Nrf2 induced by edaravone.

Classes IPC  ?

• A61K 31/4152 - 1,2-Diazoles ayant des groupes oxo liés directement à l'hétérocycle, p. ex. antipyrine, phénylbutazone, sulfinpyrazone
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

A system for cost management using blockchain and encryption is provided. The system includes an access interface, a recorder, a determinator, a key generator, an encryptor, and a decryptor. The access interface is configured to provide a platform for users to log in. The recorder is for recording cost information. The determinator is configured to determine whether the cost information recorded in the recorder is non-sensitive. When the cost information is determined as being non-sensitive, the cost information is directly uploaded to and recorded on a blockchain network via a smart contractor module. When the cost information is determined as being sensitive, the key generator generates a symmetric key randomly. The encryptor is configure to encrypt the cost information using the symmetric key to obtain ciphertext information and encrypt the symmetric key using public keys to obtain encrypted keys. The encryptor sends the ciphertext information to the blockchain network.

Classes IPC  ?

• H04L 9/06 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité l'appareil de chiffrement utilisant des registres à décalage ou des mémoires pour le codage par blocs, p. ex. système DES
• H04L 9/40 - Protocoles réseaux de sécurité

Abrégé

An automatic three-dimensional (3D) joint erosion detection method and systems for the diagnosis and monitoring of rheumatoid arthritis using HR-pQCT images of a hand is provided. The method includes following steps: providing HR-pQCT images containing joint volumes as inputs; segmenting joint bones from the HR-pQCT images; separating the joint bones from joint space based on the joint segmentation; constructing a cortical surface from the joint separation; estimating surface curvature from the cortical surface; aggregating concave regions based on the surface curvature; and determining erosion regions from the concave regions. The performance of the 3D joint erosion detection method is demonstrated to be superior to the performance of the existing methods.

Classes IPC  ?

• G06T 7/00 - Analyse d'image

Abrégé

The present disclosure provides a sensor system comprising a sensor array including a plurality of sensors and is configured to generate analog signals; an amplifier coupled to the sensor array, the amplifier configured to amplify the received analog signal; a buffer in communication with the amplifier, the buffer is configured to receive the amplified analog signal from the amplifier and cache the amplified analog signal therein; an analog-to-digital converter coupled to the amplifier and the buffer, and a signal selector configured to control delivery of the amplified analog signal from the amplifier.

Classes IPC  ?

• H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p. ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
• G16Y 40/20 - AnalyseDiagnostic

Abrégé

The subject invention pertains to hexacyclic xanthones isolated from marine bacteria. These chrexanthomycins are effective TRPV1 inhibitors that are effective as analgesics.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
• A61K 47/20 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p. ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

Compositions and methods are provided for the assessment and treatment of age-related conditions and diseases. Also provided are methods for identifying compounds that can potentially regulate the aging process.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

A synchronous coefficient of drag alteration method and system for concentrating and purifying nucleic acids from a sample containing unwanted molecules and contaminants are provided. The method includes providing a layer of artificial gel or sieve filled with liquid and into which molecules including nucleic acids are introduced from a sample liquid by applying a steady electric field across a boundary between the artificial gel layer and the sample liquid containing the molecules including nucleic acids; providing a plurality of electrodes spaced apart around circumference of the artificial gel layer and for delivering a pre-programmed sequence of voltage waveforms to establish a primary electric field driving molecules within the artificial gel layer and a secondary electric field altering electrophoretic mobility of molecules within the artificial gel layer. The nucleic acids alone are spatially separated from the unwanted molecules and contaminants to be relatively purified and enriched.

Classes IPC  ?

• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
• G01N 27/447 - Systèmes utilisant l'électrophorèse
• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]

Abrégé

The present invention relates to protein markers relevant to mild cognitive impairment (MCI) and Alzheimer's disease (AD), especially those detectable in blood samples. Thus, methods and compositions are provided for risk assessment and early diagnosis of MCI and AD based on the analysis of these protein markers. Further provided are methods and compositions useful for evaluating the efficacy of a therapy for MCI or AD.

Classes IPC  ?

• G16B 25/10 - Profilage de l’expression de gènes ou de protéinesEstimation ou normalisation de ratio d’expression

Abrégé

A neurite growth stimulator is a small molecule ENPP1 inhibitor. The small molecule ENPP1 inhibitor allows treatment of a central nervous system (CNS) injury with promotion of axon regeneration. The ENPP1 inhibitor in a vehicle can be administered to a neurological injury to promote the regeneration of axons.

Classes IPC  ?

• A61K 31/517 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. quinazoline, périmidine
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• C07D 471/00 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes du système condensé, au moins un cycle étant un cycle à six chaînons avec un atome d'azote, non prévus dans les groupes
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux

Abrégé

A coating composite including an outer slippery interface layer disposed on a surface of a photothermal layer, wherein the outer slippery interface layer includes a first poly(dialkylsiloxane) and an oil; and the photothermal layer includes photothermal nanoparticles and a second poly(dialkylsiloxane), a kit including the coating composite precursors, and methods of preparing the coating composite. The coating composite exhibits anti-icing and anti-frosting properties.

Classes IPC  ?

• C09D 143/04 - Homopolymères ou copolymères de monomères contenant du silicium
• C08F 30/08 - Homopolymères ou copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et contenant du phosphore, du sélénium, du tellure ou un métal contenant un métal contenant du silicium
• C08K 3/28 - Composés contenant de l'azote
• C09D 7/63 - Adjuvants non macromoléculaires organiques
• C09D 7/80 - Procédés pour l'incorporation d'ingrédients

Abrégé

A gate clamping circuit for driving a wide bandgap (WBG) device is provided. The gate clamping circuit comprises: a semiconductor switching device having a high side terminal connected to a gate of the WBG device; and a low side terminal connected to a source of the WBG device; a clamping resistor having a first end connected to a negative power supply terminal of a driver chip; and a second end connected to a control terminal of the semiconductor switching device; and a clamping capacitor having a first end connected to the second end of the clamping resistor; and a second end connected to the low side terminal of the semiconductor switching device; wherein the gate clamping circuit is configured to clamp negative voltage spike generated at the gate of the WBG device to suppress overstress of the gate of the WBG device when a negative off-state gate voltage is applied.

Classes IPC  ?

• H03K 17/081 - Modifications pour protéger le circuit de commutation contre la surintensité ou la surtension sans réaction du circuit de sortie vers le circuit de commande

Abrégé

The subject invention pertains to the multiplex detection of nucleic acid molecules. This invention provides oligonucleotides labeled with a fluorophore and a quencher and oligonucleotides with target binding regions that are broadly compatible with the detection of multiple variant locus or multiple nucleic acid samples. Additionally, this disclosure also describes methods to label detection targets by asymmetric labeled amplification and differentiate the target sequences.

Classes IPC  ?

• C12Q 1/6818 - Tests d’hybridation caractérisés par les moyens de détection impliquant l’interaction de plusieurs marqueurs, p. ex. transfert d’énergie de résonance
• C12Q 1/6844 - Réactions d’amplification d’acides nucléiques

Abrégé

One example embodiment is a method for preparing a sample including one or more RNA molecules, including the steps of: (i) reacting the sample with a reaction mixture including a poly(A) polymerase and one or more predefined nucleotide analogues to add a first sequence including one or more predefined nucleotide analogues to individual 3′-end of the one or more RNA molecules, such that one or more first tailed RNA is formed; and (ii) adding a plurality of adenosine triphosphates (ATP) to the reaction mixture, such that the first tailed RNA is reacted with a plurality of adenosine triphosphates (ATP) to add a second sequence including a plurality of adenine nucleotides to individual 3′-end of the first tailed RNA, such that one or more second tailed RNA is formed. Other example embodiments are described herein. In certain embodiments, the disclosed methods and kits are quick, simple and easy to operate.

Classes IPC  ?

• C12Q 1/6874 - Méthodes de séquençage faisant intervenir des réseaux d’acides nucléiques, p. ex. séquençage par hybridation [SBH]
• C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]

Abrégé

Provided is a modified poly (A) tail for use in a recombinantly produced mRNA molecule for the purpose of improving protein expression from the mRNA. Thus, new and effective compositions and methods useful for enhancing the expression of a protein of interest are provided.

Classes IPC  ?

• C12N 15/11 - Fragments d'ADN ou d'ARNLeurs formes modifiées
• C12N 15/67 - Méthodes générales pour favoriser l'expression

Abrégé

A nickel-titanium alloy, and a preparation method therefor and a use thereof. The nickel-titanium alloy comprises titanium, nickel, copper and optional cobalt; based on the total weight of the nickel-titanium alloy, the weight percentages of the titanium, nickel, copper and optional cobalt are respectively: titanium: 38-47%; nickel: 35-50%; copper: 3-20%; and optional cobalt: 0-5%. The nickel-titanium alloy does not suffer from structural fatigue and/or functional fatigue after being subjected to at least ten million loading-unloading cyclic phase transformations.

Classes IPC  ?

• C22C 19/03 - Alliages à base de nickel ou de cobalt, seuls ou ensemble à base de nickel
• C22C 14/00 - Alliages à base de titane
• C22F 1/00 - Modification de la structure physique des métaux ou alliages non ferreux par traitement thermique ou par travail à chaud ou à froid
• C22F 1/10 - Modification de la structure physique des métaux ou alliages non ferreux par traitement thermique ou par travail à chaud ou à froid du nickel ou du cobalt ou de leurs alliages

Abrégé

A technique for detection, classification and location identification of defects in a pressurized pipe network uses supervised machine learning and transient response signals (TRSs) of potential defect scenarios as training data. The TRSs are obtained from a model and/or measurements. The TRSs are arranged in an appropriate matrix form and its singular vectors (SVs) are obtained using singular value decomposition. The defect detection and classification procedure is conducted by projecting a measured TRS of the pipe network into a SV space. The location of the measured TRS in the SV space indicates the state of defective pipe section (if any), classify the defect according to clusters of training data (e.g., leak, blockage), and locate the defect within an identified defective section. The technique can accurately detect defective pipes in a network with a training data set as small as three scenarios per pipe section and one single measurement location.

Classes IPC  ?

• F17D 5/02 - Prévention, interception ou localisation des pertes
• G01M 3/28 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour tuyaux, câbles ou tubesExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour raccords ou joints d'étanchéité de tuyauxExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par mesure du taux de perte ou de gain d'un fluide, p. ex. avec des dispositifs réagissant à la pression, avec des indicateurs de débit pour soupapes

Abrégé

Provided is a safe and effective photosensitizer that expands the clinical use of photodynamic therapy (PDT) as a non-invasive cancer treatment. Specifically, Provided are methods of using water-soluble chlorophyll protein (WSCP) as a new photosensitizer for cancer phototherapy. Advantageously, WSCP is stable, non-toxic, and biocompatible while generating reactive oxygen species, making it useful for deep-tissue PDT.

Classes IPC  ?

• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
• A61P 35/00 - Agents anticancéreux

Abrégé

A transient-based time reversal (TR) technique for acoustic imaging of a pressurized water supply pipeline is provided. Measured multi-input-multi-output (MIMO) imaging data at high frequency (10kH-100 kHz) are processed by an adapted Time Reversal-MUltiple SIgnal Classification (TR-MUSIC) algorithm to provide a high-resolution image of a pipeline section about 100 m long. The resultant image reveals the pipe wall inner and outer condition, and incipient and existing defects at a scale up to millimeters. The technique is tested and validated in a laboratory environment and in a large-scale facility on pressurized water-filled viscoelastic high-density polyethylene pipes. Furthermore, the technique can be applied to different fluids and pipe materials. In addition, the technique is computationally efficient, and nondestructive. The technique requires only local intrusion for placing transducers at an access point.

Classes IPC  ?

• G01M 3/24 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des vibrations infrasonores, sonores ou ultrasonores
• G01N 29/06 - Visualisation de l'intérieur, p. ex. microscopie acoustique
• G01N 29/14 - Recherche ou analyse des matériaux par l'emploi d'ondes ultrasonores, sonores ou infrasonoresVisualisation de l'intérieur d'objets par transmission d'ondes ultrasonores ou sonores à travers l'objet utilisant des techniques d'émission acoustique
• G01N 29/24 - Sondes
• G01N 29/42 - Détection du signal de réponse par filtrage en fréquence