Abrégé

FNDC1, COL3A1, CX3CR1, SLC16A5, EPM2A, SLC35B3, PRTFDC1, CSRNP2, CCL16, HOXB4, GVINP1, LOC339874, MTRNR2L1LOC148709LOC148709, as an active ingredient.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• G01N 33/92 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des lipides, p. ex. le cholestérol
• G01N 30/72 - Spectromètres de masse

Abrégé

The present invention relates to a cyclic iRGD-conjugated lipid nanoparticle composition with improved blood-brain barrier permeability and a drug carrier comprising same. More specifically, the present invention provides a cyclic iRGD-conjugated lipid nanoparticle composition that targets αvβ3 and αvβ5 integrins, which are abundant in tumor vasculature at the blood-brain barrier, by preparing lipid nanoparticles comprising cyclic iRGD-conjugated lipids so as to enhance drug delivery to lesion sites in the brain. Furthermore, using in vitro blood-brain barrier model experiments, it was confirmed that more cyclic iRGD-conjugated lipid nanoparticles were detected in glioblastoma than the control group and R-iRGD-conjugated lipid nanoparticles, better cellular uptake occurred, drug loading rate improved as total lipid capacity increased, and a larger amount of drug was released under conditions similar to a living body. Therefore, the cyclic iRGD-conjugated lipid nanoparticle composition with improved blood-brain barrier permeability according to the present invention and the drug carrier comprising same are expected to achieve excellent preventive and therapeutic effects in various brain diseases.

Classes IPC  ?

• A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

One aspect of an embodiment of the present invention may provide a multipurpose device for monitoring an infant health condition, the device comprising: a head part having one surface on which a gripping part configured to be gripped by an infant's hand is formed, and the other surface on which a contact part is formed, the contact part being configured to be in direct contact with the infant's body to measure a biosignal or having an inwardly recessed central groove or an edge groove formed on the periphery thereof so as to be coupled to a nipple part; a sensor part provided on the head part to measure a biosignal of an infant at play; and a control part for determining the health condition of the infant on the basis of the measured biosignal. Accordingly, the health condition of an infant, including body temperature, pulse, oxygen saturation, electrical conductivity of the skin, and pressure, can be determined through multiple channels and can be transmitted to an external device, thereby monitoring the health condition of the infant.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/01 - Mesure de la température de parties du corps
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
• A61B 5/0533 - Mesure de la réaction cutanée galvanique

Abrégé

2233 layer) formed on the silicon dioxide layer.

Classes IPC  ?

• G01N 3/307 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant une force unique et brève engendrée par un ressort en compression ou en extensionRecherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant une force unique et brève engendrée par des moyens pneumatiques ou hydrauliques
• G01N 3/12 - Test de pression

Abrégé

According to a prostate cancer diagnosis system and method for predicting prostate cancer by digitally converting tactile sensations of a user, as proposed in the present invention, the prostate cancer diagnosis system comprises: a prostate cancer measurement device that images tactile sensations by using electrodes applied according to changes in elasticity of prostate tissues to which pressure is applied; and a mobile device that receives numerical data about imaged prostate tactile sensations from the prostate cancer measurement device, analyzes the presence of tissues on the basis of the numerical data about the prostate tactile sensations, diagnoses prostate cancer through a result of analyzing the numerical data, and outputs the diagnosis. Thus, by using a small tactile sensor, prostate cancer can be palpated and early-stage prostate nodules can be easily diagnosed without relying on experts.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

According to an embodiment of the present invention, a method for predicting an early neurological deterioration (END) of a patient by using a plurality of artificial intelligence models may be provided, the method comprising the steps of: acquiring an original brain image and clinical information of the patient from a server; outputting a lesion image of the original brain image by inputting the original brain image into a first artificial intelligence model that performs lesion analysis on a brain image; outputting a first probability value, which is a probability of occurrence of the END of the patient, by inputting the original brain image and the lesion image into a second artificial intelligence model; outputting a second probability value, which is a probability of occurrence of the END of the patient, by inputting the clinical information into a third artificial intelligence model; and on the basis of the first probability value and the second probability value, calculating a final probability value that is a probability of occurrence of the END of the patient.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition

Abrégé

The present invention relates to a marker composition for the diagnosis or prognosis prediction of non-alcoholic fatty liver disease and a diagnosis method using same. The inventors of the present invention confirmed that the expression level of a lipocalin-2 gene or a protein encoded thereby was increased in samples from patients with non-alcoholic fatty liver disease and/or liver fibrosis, and when this is used, non-alcoholic fatty liver disease and/or liver fibrosis can be accurately and rapidly diagnosed.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

Provided is a hybrid ring-type smart stethoscope and a method for producing the same, and the hybrid ring-type smart stethoscope includes: a connection part which has a hollow hole into which a user's finger is inserted; an upper structure which is provided on the top of the connection part; and a lower structure which is provided on the bottom of the connection part, and has a measurement module collecting body-related information, which includes the user's heartbeat or respiratory information, by coming into contact with the user. The method of producing a hybrid ring-shaped smart stethoscope includes the steps of: preparing a connection part for wearing on a user's finger; installing an upper structure on the top of the connection part in a foldable manner; and installing a lower structure on the bottom of the connection part in a foldable manner. Therefore, the hybrid ring-type smart stethoscope can effectively auscultate a user's pulse and cardiopulmonary sounds, and is conveniently portable on an ordinary day.

Classes IPC  ?

• A61B 7/04 - Stéthoscopes électriques
• A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
• A61B 7/00 - Instruments d'auscultation

Abrégé

The present invention provides a depth data-based pressure ulcer diagnosis system and method using a multispectral light source, the system comprising: a light emission unit for irradiating the skin of a body part with light in order to diagnose a pressure ulcer; a measurement unit which measures light transmittance using reflected light that is reflected from the skin of the body part when the skin of the body part is irradiated with light in order to diagnose a pressure ulcer; and a pressure ulcer diagnosis unit which diagnoses the condition of a pressure ulcer on the basis of the light transmittance measured by the measurement unit, wherein the optical principle that the transmittance of light from a multispectral light source through the skin differs according to wavelength can be used to detect skin abnormalities caused by pressure ulcers.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients

Abrégé

The present invention provides a device for measuring glycated hemoglobin measurement using carbon electrodes, a biosensor for simultaneous measurement of glucose and glycated hemoglobin, using same, and a method for simultaneous measurement of glucose and glycated hemoglobin, using the biosensor, wherein the biosensor includes a first measurement electrode, formed on the surface of a measuring part compartmentalized on a base substrate, for measuring a blood glucose level with a single drop of a sample introduced into the measuring part, and a second measurement electrode, formed around the first measurement electrode, for measuring a blood glycated hemoglobin level with a single drop of the sample introduced into the measuring part, whereby the sensor allows for the simultaneous measurement of blood glucose and glycated hemoglobin levels with a single drop of sample, offering a cheaper and simpler measurement method than conventional ones, enables the collection of both short and long-term information about a patient's blood sugar status due to the simultaneous measurement of blood glucose and glycated hemoglobin levels, and is capable of faster measurement compared to conventional sensors, with adequate sensitivity, selectivity, and efficiency suitable for monitoring fluctuations in a patient's blood sugar.

Classes IPC  ?

• G01N 27/30 - Électrodes, p. ex. électrodes pour testsDemi-cellules
• G01N 27/327 - Électrodes biochimiques
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/72 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir les pigments du sang, p. ex. l'hémoglobine, la bilirubine

Abrégé

The present specification relates to a composition for external application on the skin for radiation protection, and a method for preparing same. According to the present disclosure, the composition can directly protect the skin by comprising a body-friendly radiation shielding material, and can be useful in the field since it is possible to control the specific amount used to prevent radiation exposure. According to the present disclosure, the radiation shielding material is uniformly dispersed in the composition, is long lasting, and has excellent formulation stability even when stored for a long period of time. Therefore, the composition of the present disclosure can be useful in various industrial fields that require radiation shielding performance, such as medicine and construction.

Classes IPC  ?

• A61K 33/00 - Préparations médicinales contenant des ingrédients actifs inorganiques
• A61K 33/10 - CarbonatesBicarbonates
• A61K 33/22 - Composés du bore
• A61K 33/245 - BismuthSes composés
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61P 17/16 - Émollients ou protecteurs, p. ex. contre les radiations

Abrégé

The present invention relates to a method for manufacturing a novel lightweight radiation shield by creating a pattern of a multi-layer thin film structure of a Morpho butterfly wing by electrospinning a polymer composite material. According to the present invention, it is possible to provide lightweight shielding paper that exhibits excellent shielding performance even when made of an eco-friendly shielding material rather than lead, which is a dangerous material. The shielding paper can be laminated and thereby usefully used in medical radiation shielding suits requiring mobility, as well as various other industrial fields.

Classes IPC  ?

• G21F 1/12 - Matériaux de blindage laminés

Abrégé

A lipocalin 2 Inhibitor of the present invention can exhibit the effects of preventing and treating liver fibrosis by inhibiting the induction of liver cells into hepatic stellate cells through the inhibition of lipocalin 2 expression, and thus a pharmaceutical composition comprising same is expected to be used in therapeutic agents and the like for exhibiting excellent treatment effects on liver fibrosis.

Classes IPC  ?

• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• A23L 33/13 - Acides nucléiques ou leurs dérivés

Abrégé

Proposed are a non-contact image-based blood pressure measurement method and system based on advanced visual intelligence, wherein a blood pressure measurement model is created by performing neural network training with an image sequence obtained by a webcam in a non-contact manner, and the blood pressure of a measurement subject is estimated with the blood pressure measurement model. Accordingly, since the webcam for obtaining a video, that is, an image sequence, in a non-contact manner is used, blood pressure is continuously estimated during the recording with the webcam without contact with a device or another person, and blood pressure is estimated just by being in front of the webcam, so the system is easy to use, inexpensive, and secures sufficient precision by using a neural network algorithm.

Classes IPC  ?

• A61B 5/026 - Mesure du débit sanguin
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
• G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]
• G06V 10/60 - Extraction de caractéristiques d’images ou de vidéos relative aux propriétés luminescentes, p. ex. utilisant un modèle de réflectance ou d’éclairage
• G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients

Abrégé

This stone analysis method for a urinary stone patient comprises steps in which an analysis device: receives clinical information about the urinary stone patient together with a three-dimensional computed tomography (CT) image of the urinary stone patient; segments stones in the three-dimensional CT image by using a critical value; calculates a variant coefficient of stone density (VCSD) from the segmented stones; and determines whether the stones of the patient are uric acid stones on the basis of the VCSD and the clinical information about the urinary stone patient.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• A61B 6/03 - Tomographie informatisée
• A61B 6/12 - Agencements pour détecter ou localiser des corps étrangers
• G06T 7/00 - Analyse d'image
• G06T 7/11 - Découpage basé sur les zones
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux

Abrégé

The present invention relates to a method for manufacturing a Fe-xSi(x=4-10.0wt%) alloy compressed powder core by high-temperature molding and a high-temperature molded, Fe-xSi(x=4-10.0wt%) alloy compressed powder core manufactured by the manufacturing method, the method comprising: (a) a coating step of coating a metal alloy powder with an insulator (coating agent), (b) a lubricant mixing step of mixing a lubricant with the metal alloy powder coated with the insulator (coating agent), (c) a primary molding step of primarily molding the coated metal alloy powder at room temperature, (d) a secondary molding step of secondarily molding the coated metal alloy powder at a high temperature, and (e) a heat treatment step, whereby the alloy compressed powder core is higher in molding density and permeability and lower in iron loss compared to those manufactured by conventional room temperature molding methods.

Classes IPC  ?

• H01F 41/02 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants
• B22F 1/16 - Particules métalliques revêtues d'un non-métal
• B22F 1/12 - Poudres métalliques contenant des particules non métalliques
• B22F 3/00 - Fabrication de pièces ou d'objets à partir de poudres métalliques, caractérisée par le mode de compactage ou de frittageAppareils spécialement adaptés à cet effet
• B22F 9/00 - Fabrication des poudres métalliques ou de leurs suspensionsAppareils ou dispositifs spécialement adaptés à cet effet
• C22C 1/11 - Fabrication d'alliages amorphes

Abrégé

The present specification relates to a radiation-shielding film and a manufacturing method therefor. According to the present disclosure, an eco-friendly radiation-shielding film that is manufacturable at low cost can be provided by comprising an eco-friendly radiation-shielding material and employing waste plastics, as a polymer base to be mixed with the shielding material. The present disclosure exhibits excellent radiation-shielding performance even through manufactured with a thin thickness, by improving the mixability of a radiation-shielding material and waste plastics, and thus can be helpfully used for various products and in various industrial fields requiring radiation-shielding films, such as medical or construction fields.

Classes IPC  ?

• G21F 1/10 - Substances organiquesDispersions dans des supports organiques
• B29B 17/02 - Séparation de matières plastiques des autres matières
• B29D 7/01 - Pellicules ou feuilles
• B29B 17/04 - Désintégration des matières plastiques
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
• C08K 3/08 - Métaux
• C08K 3/22 - OxydesHydroxydes de métaux
• C08K 3/30 - Composés contenant du soufre, du sélénium ou du tellure

Abrégé

The present invention relates to a composition that substitutes for fetal bovine serum (FBS). More specifically, the composition includes an insect protein hydrolysate for use in cell cultures and when used for various animal-derived cell cultures, including human, has been confirmed to have the effects on cell growth which are equivalent or even superior to those when FBS is included while enabling a reduction in the usage of FBS, which is both costly and presents ethical issues. Therefore, the composition with the insect protein hydrolysate can be used as a substitute for fetal bovine serum and can find advantageous applications in cultured meat and various food industries that use same as an ingredient as well as in cell cultures of the bio-sector.

Classes IPC  ?

• C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
• C12N 1/38 - Stimulation chimique de la croissance ou de l'activité par addition de composés chimiques qui ne sont pas des facteurs essentiels de croissanceStimulation de la croissance par élimination d'un composé chimique
• C12P 21/06 - Préparation de peptides ou de protéines préparés par hydrolyse d'une liaison peptidique, p. ex. hydrolysats

Abrégé

A single-port laparoscopic surgical robot according to an embodiment of the present invention comprises: a plurality of surgical arms of which the angles and heights are controlled; and a surgical module which is installed on one or two or more surgical arms among the plurality of surgical arms, and performs surgery by penetrating a retractor inserted into a patient's abdomen, wherein the surgical module includes a surgical frame on which surgical devices are installed at an end, and linkages frame coupled to the surgical arms and transmitting power to the surgical device provided on the surgical frame, and the linking frames are bent in opposite outward directions to prevent interference between the linking frames operating outside the patient's abdomen, thereby making it possible to minimize interference between surgical devices that occurs during surgery.

Classes IPC  ?

• A61B 34/35 - Robots chirurgicaux pour la téléchirurgie
• A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs
• A61B 34/30 - Robots chirurgicaux

Abrégé

22); preparing a first mixture comprising the modified silicon nanoparticles, carbon nanofibers, and citric acid; manufacturing an assembly by electrostatically self-assembling the first mixture and graphene oxide (GO); preparing an intermediate by hydrothermally synthesizing a second mixture comprising the assembly, melamine, and formaldehyde resin; and calcining the intermediate.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
• H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
• C01B 33/02 - Silicium
• C01B 32/158 - Nanotubes de carbone
• C01B 32/168 - Post-traitement
• C01B 32/194 - Post-traitement
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
• H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif

Abrégé

The present invention relates to a titanium oxide phase change producing apparatus, system and method, using the number of shock wave exposures, a handy shock wave tube device, and a system and method for testing material characteristics comprising same. An embodiment of the present invention provides a titanium oxide phase change producing apparatus using the number of shock wave exposures, the titanium oxide phase change producing apparatus comprising: a shock wave tube that is formed as a tube having a circular or polygonal cross section and is capable of measuring the impact of shock waves; and a test model that is disposed at the other end of the shock wave tube to form an end wall and has an anatase titanium dioxide nanoparticle sample attached to one side so that a phase change occurs according to the number of shock wave exposures. Another embodiment of the present invention provides a handy shock wave tube device comprising: a shock wave tube which is formed as a tube having a circular or polygonal cross section and is capable of measuring the impact of shock waves; a pressure part that supplies gas to the shock wave tube to apply pressure thereto; and a driver that drives parts of the shock wave tube to be separated and coupled.

Classes IPC  ?

• G01M 9/06 - Dispositions pour la mesure spécialement adaptées aux tests aérodynamiques
• G01M 9/04 - Souffleries Détails
• G01N 3/12 - Test de pression
• G01N 3/30 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique en appliquant une force unique et brève
• G01L 19/08 - Moyens pour l'indication ou l'enregistrement, p. ex. pour l'indication à distance

Abrégé

The present invention proposes a device and method for restoring digital pathology staining by using a GAN. The device comprises: a generation network for generating similar false data on the basis of original data which is actual learning data; and a determination network for using and learning the false data generated from the generation network, and original data which is actual learning data and determining whether data input thereto is the actual learning data or the false data. Therefore, among staining data produced currently, data that is unusable due to loss of staining can be digitally restored to its original state.

Classes IPC  ?

• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
• G06N 3/08 - Méthodes d'apprentissage
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion
• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
• G01N 1/30 - TeintureImprégnation

Abrégé

The present application relates to a radiation shielding film using tungsten powder and a preparation method for the radiation shielding film. The radiation shielding film is prepared in the form of an ultra-thin film while still including tungsten particles at high density, as eco-friendly radiation shielding materials that replace lead, and thus may be excellent in both flexibility and radiation shielding ratio, thereby being usefully applicable in radiation shielding suits for medical institutions as well as in various fields requiring radiation shielding films. The radiation shielding film includes tungsten powder and a polymer base, wherein the tungsten powder has an average particle size of 80-200 nm, and the film has a thickness of 0.1-0.025 mm.

Classes IPC  ?

• G21F 1/10 - Substances organiquesDispersions dans des supports organiques
• G21F 1/12 - Matériaux de blindage laminés
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08K 3/08 - Métaux
• C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés

Abrégé

The present invention relates to novel PIM kinase inhibitors and uses thereof and, more specifically, to a novel compound having PIM kinase inhibitory activity and a composition for the prevention, amelioration or treatment of diseases related to PIM kinase activity, comprising same. The compound of the present invention was confirmed to have effective PIM kinase inhibitory activity while having low cardiotoxicity, and thus can be effectively used as a composition for the prevention, amelioration or treatment of various diseases related to PIM kinase activity, such as cancer, autoimmune diseases, myeloproliferative disorders, or atherosclerosis.

Classes IPC  ?

• C07D 401/04 - Composés hétérocycliques contenant plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, au moins un cycle étant un cycle à six chaînons avec un unique atome d'azote contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
• A61K 31/4545 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pipampérone, anabasine
• A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
• A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
• A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
• A61K 31/553 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole ayant au moins un azote et au moins un oxygène comme hétéro-atomes d'un cycle, p. ex. loxapine, staurosporine
• A61P 35/00 - Agents anticancéreux
• A61P 37/00 - Médicaments pour le traitement des troubles immunologiques ou allergiques
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
• C07D 405/14 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles

Abrégé

The present invention relates to a smart infant stethoscope and an infant health status monitoring system including same, the smart infant stethoscope comprising: insertion portions that have rubber caps coupled to the outside thereof and are inserted into the ears; a head portion having, on one side thereof, a gripping portion that is held by the hand and, on the other side, a contact portion which comes into contact with the body; sensor units provided in the insertion portions and the head portion to measure biological signals of an infant at play; and a control unit that assesses the health condition of the infant on the basis of the measured biological signals. Accordingly, the health status of infants, including body temperature, pulse waves, oxygen saturation, and skin conductance, can be assessed through multiple channels and be transferred to an external device, so that the health status of infants can be monitored.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/01 - Mesure de la température de parties du corps
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
• A61B 5/0533 - Mesure de la réaction cutanée galvanique
• A63H 33/30 - Imitations d'appareils, non prévues ailleurs, p. ex. de téléphones, de balances ou de caisses enregistreuses
• A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux

Abrégé

The present invention relates to a biomarker for the diagnosis of pre-diabetes and diabetes, and a use thereof, and more specifically, to: a composition and a kit for the diagnosis of pre-diabetes or diabetes, the composition and kit comprising an agent for measuring the expression level of at least one selected from among four piRNAs; and a method for diagnosing pre-diabetes or diabetes by using the marker. The present inventors analyzed the expression level of piRNA contained in exosomes isolated from the blood of a normal group, a pre-diabetic patient group, and a diabetic patient group, and thus, found four piRNA (hsa-piR-31447, hsa-piR-33226, hsa-piR-36246, and hsa-piR-49124) markers capable of distinguishing the normal group, the pre-diabetic patient group, and the diabetic patient group. Also, it was confirmed that using the four piRNA markers makes it possible to diagnose pre-diabetes and/or diabetes accurately and rapidly, and thus the piRNA can be effectively used as a biomarker for the diagnosis of pre-diabetes and/or diabetes.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• C12Q 1/686 - Réaction en chaine par polymérase [PCR]

Abrégé

The present invention relates to a blockchain data storage method performed by a blockchain data storage management device for storing data by using a blockchain, comprising steps in which: a plurality of nodes included in a blockchain network is clustered by service so as to generate service-specific groups; blockchain nodes included in the service-specific groups are designated as specific nodes on the basis of a predetermined condition; the specific nodes generate a block on the basis of a transaction when the transaction is received from a service user; and blockchain data based on the block is stored in local storage possessed by blockchain nodes included in the service-specific groups. Therefore, latency time and data reliability are ensured by maintaining asynchronously through the local storage maintained in the blockchain node, data stored in the blockchain is stored in the storage divided by service, and a synchronization transaction is generated through a method of agreeing before storing, by node, data in the local storage, and thus reliability can be guaranteed.

Classes IPC  ?

• H04L 67/1097 - Protocoles dans lesquels une application est distribuée parmi les nœuds du réseau pour le stockage distribué de données dans des réseaux, p. ex. dispositions de transport pour le système de fichiers réseau [NFS], réseaux de stockage [SAN] ou stockage en réseau [NAS]
• H04L 67/1042 - Réseaux de pairs [P2P] en utilisant des mécanismes de gestion de la topologie
• H04L 9/00 - Dispositions pour les communications secrètes ou protégéesProtocoles réseaux de sécurité

Abrégé

An embodiment of the present invention relates to a virtual collaboration non-contact real-time remote experimental system. An embodiment of the present invention provides a virtual collaboration non-contact real-time remote experimental system comprising: a virtual reality (VR) headset that is carried by a user, captures an image of the user to obtain user image information, and displays an avatar generated using the user image information and virtual reality contents for a non-contact real-time remote experiment; and a metaverse platform server that generates the avatar and the virtual reality contents and provides same to the VR headset, and controls implementation and/or operation of the virtual reality contents on the basis of input information of the user which is received from the VR headset.

Classes IPC  ?

• G06Q 10/10 - BureautiqueGestion du temps
• G02B 27/01 - Dispositifs d'affichage "tête haute"
• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
• G06V 40/20 - Mouvements ou comportement, p. ex. reconnaissance des gestes
• G06T 13/40 - Animation tridimensionnelle [3D] de personnages, p. ex. d’êtres humains, d’animaux ou d’êtres virtuels
• G06T 3/40 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement
• G01P 1/07 - Dispositifs indicateurs, p. ex. pour l'indication à distance

Abrégé

A method for classifying a uric acid content of a urinary stone by using a radiomics parameter comprises the steps of: receiving, by an analysis device, a CT image of a subject; segmenting, by the analysis device, a region of a urinary stone from the CT image; extracting, by the analysis device, radiomics parameters from the region of the urinary stone; and classifying, by the analysis device, an uric acid component of the urinary stone, on the basis of a value calculated by inputting the radiomics parameters into a pretrained learning model.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• A61B 6/03 - Tomographie informatisée
• A61B 6/12 - Agencements pour détecter ou localiser des corps étrangers
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition

Abrégé

The present invention provides a fluorometric assay substrate for the simultaneous measurement of glucose and lactate, wherein an identical substrate (Amplex Red) that reacts with glucose and lactate and a catalyst (horseradish peroxidase: HRP) are used such that the setting of protocols for assaying both glucose and lactate is convenient, an assay procedure for measuring glucose and lactate can be simplified, the concentrations of glucose and lactate are measured simultaneously, thus making the measuring of glucose and lactate concentration convenient, and the measured concentrations of glucose and lactate can be used to measure obesity and embryonic activity more precisely than in the prior art.

Classes IPC  ?

• G01N 21/64 - FluorescencePhosphorescence
• C12Q 1/28 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une oxydoréductase une peroxydase
• C12Q 1/54 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir le glucose ou le galactose
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes

Abrégé

The present invention relates to a smart stethoscope, comprising: a main body including a plurality of sensors for measuring a user's bio-signals and a power supply unit; and a fixing part coupled to the front surface of the main body and provided to be foldable to fix a user's finger, wherein the main body includes: an input unit operated by a user; and a control unit that, when one of measurement modes is selected by the user's operation, measures a bio-signal at a specific sensor from among the plurality of sensors on the basis of the selected measurement mode, and calculates a measurement value corresponding to the measured bio-signal according to a preset algorithm. Accordingly, auscultation can be optimized for a user by changing a measurement frequency by changing the mode according to the user while allowing for auscultation through multi-channels including electrocardiogram, pulse waves, and heart and lung sounds.

Classes IPC  ?

• A61B 7/04 - Stéthoscopes électriques
• A61B 7/00 - Instruments d'auscultation
• A61B 5/28 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG]
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The present invention provides a method for preparing porous silica and porous silica prepared thereby, the method comprising: (a) adding, to distilled water, water glass (sodium silicate solution) as a silica precursor, followed by stirring; (b) adding a surfactant to a water glass solution formed in step (a), followed by stirring; (c) adding an acidic solution to a surfactant-added solution formed in step (b), followed by stirring, to adjust pH; and (d) performing a room-temperature reaction for a predetermined time, filtration, and then washing, thereby synthesizing porous silica.

Classes IPC  ?

• C01B 33/193 - Préparation de silice finement divisée ni sous forme de sol ni sous forme de gelPost-traitement de cette silice par traitement acide de silicates de solutions aqueuses de silicates

Abrégé

According to an EfficientNet architecture-based mobile vision system and method enabling prediction of a human's complex emotion proposed in the present invention, the system may comprise: a biosignal measurement unit for measuring a biosignal of a subject of which the emotion state is to be predicted; an image measurement unit for measuring a facial expression image of the subject of which the emotion state is to be predicted; and an emotion prediction unit that analyzes the biosignal measured by the biosignal measurement unit and the facial expression image measured by the image measurement unit to classify respective emotions, and combines the classified emotions of the biosignal and the facial expression image to predict a final emotion, thereby predicting an emotion state from a combination of a biosignal and a facial expression image of a subject rather than using only a facial expression image, so as to provide higher accuracy and maintain high recognition performance with optimal parameters.

Classes IPC  ?

• A61B 5/16 - Dispositifs pour la psychotechnieTest des temps de réaction
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/0245 - Mesure du pouls ou des pulsations cardiaques utilisant des capteurs engendrant des signaux électriques
• A61B 5/346 - Analyse des électrocardiogrammes
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
• A61B 5/026 - Mesure du débit sanguin
• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
• G06V 40/16 - Visages humains, p. ex. parties du visage, croquis ou expressions

Abrégé

The present invention provides a biosensor for the simultaneous measurement of glucose and lactate, the biosensor comprising: a base on a plate; a first reaction electrode unit that is formed on one side of the upper surface of the base, and reacts with a whole blood sample to emit electrons according to the concentration of glucose contained in the whole blood; a second reaction electrode unit that is formed adjacent to the first reaction electrode unit on the upper surface of the base, and reacts with the whole blood sample to emit electrons according to the concentration of lactate contained in the whole blood; a counter electrode unit which is formed on the upper surface of the base and around the first reaction electrode unit and the second reaction electrode unit, and through which electricity applied to the first reaction electrode unit and the second reaction electrode unit selectively flows; and an insulating cover bonded to the upper surface of the base and exposing the first reaction electrode unit, the second reaction electrode unit, and the counter electrode unit to the outside through a hole formed on one side, wherein a single drop of the whole blood sample is used to simultaneously measure the concentrations of glucose and lactate.

Classes IPC  ?

• G01N 27/327 - Électrodes biochimiques
• C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
• C12Q 1/54 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir le glucose ou le galactose
• G01N 33/483 - Analyse physique de matériau biologique

Abrégé

The present specification relates to a radiation shielding fiber using tungsten powder and a method for preparing the radiation shielding fiber, wherein tungsten particles, an eco-friendly radiation shielding material replacing lead, are directly and uniformly sprayed and coated on a base fiber, so both flexibility and radiation shielding rate are excellent, making it easy to use in various fields that require radiation shielding fibers other than radiation shielding clothing for medical institutions. The radiation shielding fiber according to the present invention includes a base fiber and a radiation shielding material coating layer coated on one surface of the base fiber, wherein the radiation shielding material coating layer is made of a mixture of tungsten powder and at least one inorganic material selected from tin and cobalt.

Classes IPC  ?

• G21F 1/08 - MétauxAlliagesCermets, c.-à-d. mélanges frittés de céramiques et métaux
• G21F 3/02 - Habillement

Abrégé

According to a perfusion imaging-based non-contact autonomic nervous system response multi-dimensional bio-signal measurement system and method proposed in the present invention, the present invention comprises: a light source unit for irradiating a light source outside a visible light region and measuring a multi-dimensional bio-signal in a non-contact manner; a multi-dimensional multi-spectral camera for photographing amplified reflected light irradiated from the light source unit and then reflected and generating an image sequence of the bio-signal according to the amplified reflected light; and a measurement diagnosis unit for measuring heart rate, oxygen saturation, blood flow per second, and blood pressure through image processing of the image sequence of the bio-signal generated from the multi-dimensional multi-spectral camera through photographing, thus being able to overcome the limitations of existing individual bio-signal measurement systems, increase the accuracy of bio-signal measurement and diagnosis through image processing excluding noise observed in a visible region, and further improve the efficiency and convenience of multidimensional bio-signal measurement.

Classes IPC  ?

• A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
• A61B 5/026 - Mesure du débit sanguin
• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins

Abrégé

The present specification relates to a fiber for radiation-shielding functional clothing, and a manufacturing method therefor, and the fiber having a radiation-shielding ability and being harmless to the human body, thereby effectively protecting the body from radiation. In addition, since a radiation-shielding material is included on the inside, and not the outside, of the filament, the fiber exhibits high strength while having flexibility, breathability and lightness that are similar to those of a normal fiber, and thus is combined with additional elements such as zippers, hooks and rubber so as to be used in the manufacturing of various forms of radiation-protective functional clothing such as underwear, jackets or scarves.

Classes IPC  ?

• A41B 9/00 - Sous-vêtements
• G21F 3/02 - Habillement
• D03D 1/00 - Tissus conçus pour faire des articles particuliers
• D03D 11/00 - Tissus doubles ou à couches multiples non prévus ailleurs
• D03D 15/283 - Tissus caractérisés par la matière, la structure ou les propriétés des fibres, des filaments, des filés, des fils ou des autres éléments utilisés en chaîne ou en trame caractérisés par la matière des fibres ou des filaments formant les filés ou les fils à base de polymères synthétiques, p. ex. fibres polyamides ou fibres polyesters
• D01F 1/10 - Autres agents modifiant les propriétés de ces filaments
• D01D 5/08 - Méthodes de filage à partir de masses en fusion
• D03D 15/50 - Tissus caractérisés par la matière, la structure ou les propriétés des fibres, des filaments, des filés, des fils ou des autres éléments utilisés en chaîne ou en trame caractérisés par les propriétés des filés ou des fils

Abrégé

A multi-object tracking device and method based on self-supervised learning proposed in the present invention is the first attempt to apply self-supervised learning to online multi-object tracking, applies a pose normalized GAN (PN-GAN) and image augmentation for learning considering an object's pose change, can design a MOT model generating a better result even with a less number of pieces of data by resolving the problem of lack of learning data through the PN-GAN, can generate more discrimination feature vectors during learning of an encoder network by proposing an affinity correlation distance (ACD) that is a new loss function, can learn using an end-to-end scheme, can be directly applied without additional transfer learning because additional fine tuning for classification, clustering, and regression is not required, and can take up less memory than other latest methods and provide fast and high tracking performance.

Classes IPC  ?

• G06T 7/246 - Analyse du mouvement utilisant des procédés basés sur les caractéristiques, p. ex. le suivi des coins ou des segments
• G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
• G06T 7/187 - DécoupageDétection de bords impliquant des croissances de zonesDécoupageDétection de bords impliquant des fusions de zonesDécoupageDétection de bords impliquant un étiquetage de composantes connexes
• G06N 20/00 - Apprentissage automatique

Abrégé

The present invention relates to a composition capable of distinguishing a patient suffering from ankylosing spondylitis, from rheumatic disease patients by confirming the expression of caspase-1 in a serum sample. By confirming the expression level of caspase-1 in serum, the composition of the present invention can distinguish ankylosing spondylitis from rheumatic diseases. Since only ankylosing spondylitis can be significantly diagnosed, the present invention is expected to help establish a treatment strategy for ankylosing spondylitis at an early stage.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention relates to a single embryo culture system using sound wave control. The single embryo culture system using sound wave control, according to the present invention, comprises: a substrate which is plated with a conductor; a polymer chamber in which a culture space for culturing a single embryo is formed, implemented in an open polygonal shape, and attached to the substrate; at least one pair of electrodes which are located at symmetric points on the basis of the polymer chamber and are attached to the substrate; and a sound wave control unit which generates sound waves to a single embryo present in the polymer chamber, through the at least one pair of electrodes when a voltage is applied thereto. Thus, according to the present invention, the embryo is cultured in an environment similar to living conditions by controlling the movement of the embryo to be induced using sound waves, thereby improving the success rate of in vitro fertilization.

Classes IPC  ?

• C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
• C12N 5/073 - Cellules ou tissus embryonnairesCellules fœtales ou tissus fœtaux
• C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p. ex. par magnétisme, par des ondes sonores

Abrégé

An electronic apparatus according to a disclosed aspect comprises: an electrode sensor which applies a current to an object and measures the impedance of the object; a frequency controller which adjusts the frequency of the applied current; a memory which stores a correlation between impedance and vitamin D concentration for each frequency; and a processor which, while varying the frequency, obtains the impedance of the object, identifies the correlation to which the obtained impedance belongs, and calculates a vitamin D concentration of the object on the basis of the correlation.

Classes IPC  ?

• A61B 5/0537 - Mesure de la composition du corps par impédance, p. ex. de l’hydratation des tissus ou de la teneur en graisses
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

Disclosed herein is an electronic apparatus. The electronic apparatus includes an electrode sensor configured to apply a current to an object and configured to measure an impedance of the object, a frequency controller configured to adjust a frequency of the applied current, a memory storing a correlation between an impedance and a vitamin D concentration for each frequency, and a processor configured to obtain the impedance of the object corresponding to the frequency, and to calculate a vitamin D concentration of the object based on the impedance and the correlation.

Classes IPC  ?

• A61B 5/0537 - Mesure de la composition du corps par impédance, p. ex. de l’hydratation des tissus ou de la teneur en graisses

Abrégé

In a system and a method for providing an artificial intelligence-based surgery result report using a speech recognition platform, for a surgery result report written by hand after surgery, a surgery procedure and a surgery diagnosis result are input using artificial intelligence-based speech recognition and in response thereto, a surgery result report is automatically generated. According to the present invention, a surgery procedure and a diagnosis result can be input using speech recognition, inaccuracy of input value recognition according to pronunciation can be prevented by a response selection signal configured by a number, and the convenience and accuracy in generation of a surgery result report can be enhanced.

Classes IPC  ?

• G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p. ex. leur création ou leur transmission
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G16H 10/20 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des essais ou des questionnaires cliniques électroniques
• G10L 15/26 - Systèmes de synthèse de texte à partir de la parole
• G06N 3/08 - Méthodes d'apprentissage
• G06N 20/00 - Apprentissage automatique
• G06F 16/332 - Formulation de requêtes
• G06F 40/30 - Analyse sémantique
• G06F 16/35 - PartitionnementClassement

Abrégé

The present invention relates to a novel inhibitor for multiple protein kinases, and provides: a novel indolin-2-one compound or a pharmaceutically acceptable salt thereof that exhibits excellent anti-inflammatory activity; and a composition for treating inflammatory diseases, containing same as an active ingredient. The novel compound strongly inhibits the activity of various protein kinases related to inflammation, and thus can be used as an inhibitor for multiple protein kinases, and has an excellent anti-inflammatory effect as compared to other anti-inflammatory drugs, and thus can be used in the development of therapeutic agents for inflammatory diseases.

Classes IPC  ?

• C07D 403/14 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant au moins trois hétérocycles
• A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
• A61P 19/10 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget de l'ostéoporose
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs

Abrégé

The present invention provides a blockchain-based composing device and a control method therefor, and a computer program stored in a computer-readable recording medium. The blockchain-based composing device of the present invention comprises: an input module for receiving musical elements for composing; an output module for playing and outputting a sound source according to music information; a memory for storing the music information about the composed sound source; a communication module for connecting to a blockchain network; and a processor, which generates the music information according to the musical elements inputted through the input module so as to store the music information in the memory, plays back the sound source through the output module according to the generated music information, and receives copyright information of a composer if initial music information is to be generated for composing, so as to connect to the blockchain network through the communication module, and thus record copyright information and the music information on a blockchain during composing.

Classes IPC  ?

• G10H 1/00 - Éléments d'instruments de musique électrophoniques
• G06F 21/10 - Protection de programmes ou contenus distribués, p. ex. vente ou concession de licence de matériel soumis à droit de reproduction
• G06Q 50/18 - Services juridiques
• G06Q 50/10 - Services
• H04L 67/1097 - Protocoles dans lesquels une application est distribuée parmi les nœuds du réseau pour le stockage distribué de données dans des réseaux, p. ex. dispositions de transport pour le système de fichiers réseau [NFS], réseaux de stockage [SAN] ou stockage en réseau [NAS]

Abrégé

An embodiment wireless charging vehicle includes a secondary charging pad configured to generate an induced current by a magnetic field generated to a primary charging pad of a wireless charging station and to charge a battery, a plurality of ultra-wideband (UWB) tags disposed to surround the vehicle, and a UWB controller configured to perform a wireless charging arrangement mode for arranging the secondary charging pad on the primary charging pad by using a sensor value measured by the UWB tags, wherein the UWB controller is configured to calculate a coordinate of the primary charging pad by using a line of sight (LOS) sensor value of a UWB tag having a line of sight from among the UWB tags.

Classes IPC  ?

• B60L 53/36 - Moyens pour l’ajustement automatique ou assisté de la position relative des dispositifs de charge et des véhicules par le positionnement du véhicule
• H02J 50/10 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif
• H02J 50/90 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la détection ou l'optimisation de la position, p. ex. de l'alignement
• H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
• H02J 50/80 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre l’échange de données, concernant l’alimentation ou la distribution d’énergie électrique, entre les dispositifs de transmission et les dispositifs de réception
• B60L 53/12 - Transfert d'énergie par induction
• H04W 4/80 - Services utilisant la communication de courte portée, p. ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
• G01C 22/00 - Mesure de la distance parcourue sur le sol par des véhicules, des personnes, des animaux ou autres corps solides en mouvement, p. ex. en utilisant des odomètres ou en utilisant des podomètres

Abrégé

A cholangioscopy tube according to various embodiments of the present disclosure may comprise a tube body having a first tube end and a second tube end formed therein, wherein the tube body includes: an observation hole formed adjacent to the first tube end; and an endoscope insertion part formed adjacent to the second tube end.

Classes IPC  ?

• A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
• A61B 1/01 - Dispositions pour leur guidage
• A61B 1/273 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour l'appareil digestif supérieur, p. ex. œsophagoscopes, gastroscopes
• A61B 1/015 - Commande de l'alimentation en fluide ou de l'évacuation de fluide

Abrégé

The present invention relates to a hybrid ring-type smart stethoscope and a method for manufacturing same. The hybrid ring-type smart stethoscope according to an embodiment of the present invention comprises: a connection part having a hollow hole into which a user's finger is inserted; an upper structure provided above the connection part; and a lower structure provided below the connection part and including a measurement module that, by being brought into contact with the user, collects body-related information that includes heartbeat or cardiopulmonary information of a user. The method for manufacturing the hybrid ring-type smart stethoscope according to an embodiment of the present invention, by comprising the steps of: preparing a connection part to be put on and worn by a user's finger; foldably installing an upper structure above the connection part; and foldably installing a lower structure below the connection part, has the advantage of being easy for a user to carry in everyday life while effectively auscultating the user's pulse wave and cardiopulmonary sound.

Classes IPC  ?

• A61B 7/04 - Stéthoscopes électriques
• A61B 7/00 - Instruments d'auscultation
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/022 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins par application d'une pression pour fermer les vaisseaux sanguins, p. ex. contre la peauOphtalmodynamomètres
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The present invention provides a system for measuring glucose and glycated hemoglobin, wherein: glucose is measured with separated plasma while separating plasma from blood through a red blood cell filter by allowing blood to flow through any one of a pair of channels; and hemoglobin or glycated hemoglobin produced by the destruction of red blood cells is measured by destroying the red blood cells collected in the red blood cell filter through plasma separation by allowing a buffer solution (lysis buffer) to flow through the other channel, thereby simultaneously measuring glucose, hemoglobin, and glycated hemoglobin using a small amount of blood.

Classes IPC  ?

• G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
• G01N 27/26 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant des variables électrochimiquesRecherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en utilisant l'électrolyse ou l'électrophorèse
• G01N 27/02 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance

Abrégé

The present invention relates to a distributed storage method and apparatus for managing accessible information by using a blockchain-based enterprise network. In other words, the distributed storage method: establishes, by an enterprise network based on a multi-blockchain, an ERP system being operated within an enterprise; and, while restricting, according to a security level of the enterprise network, access rights to enterprise internal documents that have been processed by computational work, distributes and stores the enterprise internal documents in units of chucks in storage apparatuses for an enterprise connected by the enterprise network.

Classes IPC  ?

• G06F 21/78 - Protection de composants spécifiques internes ou périphériques, où la protection d'un composant mène à la protection de tout le calculateur pour assurer la sécurité du stockage de données
• G06F 16/182 - Systèmes de fichiers distribués
• H04L 9/40 - Protocoles réseaux de sécurité
• H04L 67/1097 - Protocoles dans lesquels une application est distribuée parmi les nœuds du réseau pour le stockage distribué de données dans des réseaux, p. ex. dispositions de transport pour le système de fichiers réseau [NFS], réseaux de stockage [SAN] ou stockage en réseau [NAS]
• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p. ex. par clés ou règles de contrôle de l’accès
• G06F 21/60 - Protection de données

Abrégé

The present invention provides a method for manufacturing hollow PCM comprising the steps of: (a) forming polystyrene, which is a core material, by adding styrene, which is a precursor, and a thermal initiator to distilled water; (b) synthesizing core-shell structured hollow silica, by adding the polystyrene formed in step (a) to a mixed solution of distilled water and ethanol, adding cetyltrimethylammonium chloride (CTACl), which is a certain cationic surfactant, and TEOS, which is a silica precursor, and stirring for a set time, then adding an alkali material to the stirred solution, allowing to react at room temperature for a set time followed by filtering and a washing step, and then drying at a set temperature for a set time; and (c) synthesizing hybrid hollow silica, by inserting the hollow silica synthesized in step (b) to THF, adding an organic solvent in acidic conditions, refluxing for a set time, and then washing and drying.

Classes IPC  ?

• C01B 33/18 - Préparation de silice finement divisée ni sous forme de sol ni sous forme de gelPost-traitement de cette silice
• C09K 5/02 - Substances qui subissent un changement d'état physique lors de leur utilisation

Abrégé

According to the trocar for pediatric extraperitoneal hernia correction and a method for using same, which are proposed in the present invention, by comprising: a trocar housing made of a hollow shape for guiding a laparoscopic camera into an interior for pediatric extraperitoneal hernia correction; and an obturator that closes the end of the trocar housing and has a rounded end so as not to pierce the peritoneum during pediatric extraperitoneal hernia correction, the peritoneum may not be damaged by non-peritoneal surgery for complete epiperitoneal hernia correction in children, a space can be separated while a laparoscopic camera is put in place, and a field of view can be secured, thereby minimizing the inconvenience of pediatric surgery.

Classes IPC  ?

• A61B 17/34 - TrocartsAiguilles à ponction
• A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
• A61B 17/04 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour la suture des plaiesSupports ou emballages pour aiguilles ou matériaux de suture

Abrégé

The present invention relates to a sandwich enzyme-linked immunosorbent assay (ELISA)-based leptin biosensor, and a method for detecting leptin by using same, and, more specifically, to a technique for electrochemically detecting leptin by using the oxidation reaction of o-phenylenediamine (oPD) on a screen-printed gold electrode (SPGE) on the basis of a sandwich ELISA [DTSSP/leptin Ab (capture antibody)/leptin/biotinylated leptin Ab (detection antibody)/streptavidin-HRP]. When the sandwich ELISA-based leptin biosensor of the present invention was used, a leptin concentration detection curve was identified to be in the range of 0.1-20 ng/mL, and stability, sensitivity, selectivity and effectiveness that are higher than those of commercial ELISA measurement were exhibited, and thus the biosensor is applied in clinics and point-of-care testing (POCT) so as to be applicable as a medical device capable of readily checking the criterion for obesity and obesity-mediated diseases.

Classes IPC  ?

• G01N 33/74 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des hormones
• G01N 33/535 - Production de composés immunochimiques marqués avec un marqueur enzymatique
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention relates to a detection method of ransomware, a restoration method, and a computing device for performing the methods, wherein the detection method of ransomware, according to an embodiment of the present invention, may comprise the steps of: detecting an initial operation of a process for a file transmitted through a file system; when there is a possibility that the process may be determined as ransomware on the basis of the initial operation, setting a tracking mode for detecting whether the process is ransomware; after the initial operation is performed, determining whether at least one subsequent operation requested by the process for the file corresponds to an operation rule for determining ransomware; and when the at least one subsequent operation corresponds to the operation rule, determining the process as ransomware.

Classes IPC  ?

• G06F 21/56 - Détection ou gestion de programmes malveillants, p. ex. dispositions anti-virus

Abrégé

Provided is a remaining nutrient solution measuring device which receives the input of the type of a nutrient bag to be installed on a mounting part, measures a load acting on the mounting part, measures an inclination acting on the mounting part, corrects the load based on the inclination, calculates information on a remaining nutrient solution in the nutrient bag according to the load, and outputs information on the remaining nutrient solution.

Classes IPC  ?

• A61J 3/00 - Dispositifs ou procédés spécialement conçus pour donner à des produits pharmaceutiques une forme physique déterminée ou une forme propre à leur administration
• A61J 1/22 - Dispositions pour le transfert des liquides, p. ex. du flacon à la seringue avec des moyens pour doser la quantité de liquide
• A61J 1/10 - Récipients du type sac
• A61J 1/16 - Supports pour récipients
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques DétailsAccessoires à cet effet

Abrégé

Provided is a urine quantity measurement apparatus which: receives, as input, the type of a urine bag mounted on a mounting part; measures the load acting on the mounting part; measures the slope acting on the mounting part; corrects the load on the basis of the slope; calculates information about the quantity of urine inside the urine bag according to the load; and outputs the information about the quantity of urine.

Classes IPC  ?

• A61B 5/20 - Mesure des fonctions urologiques
• A61F 5/451 - Réceptacles génitaux
• A61F 5/44 - Dispositifs portés par le patient pour recueillir l'urine, les selles, les menstrues ou d'autres sécrétionsDispositifs de colostomie
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

Abrégé

The present invention relates to a biomarker for diagnosing pre-diabetes or predicting the onset of diabetic complications and use thereof and, more particularly, to: a composition and kit for diagnosing pre-diabetes or predicting the onset of diabetic complications, comprising an agent for measuring the expression level of any one or more selected from seven microRNAs; and a method for diagnosing pre-diabetes or predicting the onset of diabetic complications by using the marker. As a result of having analyzed microRNAs included in exosomes isolated from the blood of a normal group, a pre-diabetic patient group, and a diabetic patient group, the inventors of the present invention identified seven microRNAs specific to the pre-diabetic patient group. Therefore, the identified microRNAs can be used to diagnose pre-diabetes early, thus enabling the diagnosis of early diabetes, and are expected to be effectively used as biomarkers for predicting the onset of diabetes or diabetic complications.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique

Abrégé

According to a photobiomodulation method and system for inducing the activity of a brain-derived nerve growth factor in a hippocampal tissue, proposed by the present invention, a photobiomodulation (PBMT or PBM) method, which is a therapy using infrared to seat-infrared (wavelength of 600-1100 nm) light, is utilized, thereby delaying the death of cells, promoting the proliferation of meristematic cells, and inducing natural treatment without the risk of adverse reactions to a disease or lesion, in a simple and easy manner in which low-level laser light is irradiated into a living body, based on the principle that certain molecules in the living body can absorb photons and trigger signaling pathways in response to light of a specific wavelength band.

Classes IPC  ?

• A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux

Abrégé

According to a non-contact image-based blood pressure measurement method and system based on advanced visual intelligence proposed in the present invention, a neural network is trained with an image sequence captured by a webcam in a non-contact manner to generate a blood pressure measurement model, and the blood pressure of a measurement subject is measured using the blood pressure measurement model. Therefore, since the webcam with which a moving image, that is, an image sequence, is captured in a non-contact manner is used, the blood pressure can be continuously estimated while capturing images with the webcam without contact with a device or another person. Moreover, since the blood pressure is estimated from a subject merely being in front of the webcam, the present invention is highly usable and inexpensive, and sufficient precision can be attained using a neural network algorithm.

Classes IPC  ?

• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion
• G06N 3/08 - Méthodes d'apprentissage

Abrégé

The present invention provides: a method for preparing a silicon/carbon nanofiber/graphene composite, comprising the steps of (a) mixing and dispersing predetermined silicon nanoparticles and CNFs in ethanol, and then ultrasonicating the mixture for a predetermined time, so as to synthesize an Si/CNF mixture, (b) adding a GO aqueous solution to the Si/CNF mixture having been prepared in step (a), and ultrasonicating and stirring the generated mixture for a predetermined time to synthesize an Si/CNF/GO dispersion, (c) filtering the Si/CNF/GO dispersion by vacuum filtration and drying same to synthesize an Si/CNF/GO composite, and (d) synthesizing an Si/CNF/rGO composite through heat treatment; and a method for manufacturing a secondary battery by using the composite.

Classes IPC  ?

• H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
• H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
• H01M 4/587 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx pour insérer ou intercaler des métaux légers
• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p. ex. liants, charges
• H01M 10/0569 - Matériaux liquides caracterisés par les solvants
• H01M 10/052 - Accumulateurs au lithium
• C01B 32/05 - Préparation ou purification du carbone non couvertes par les groupes , , ,
• C01B 32/182 - Graphène
• C01B 33/02 - Silicium

Abrégé

The present invention relates to a method for manufacturing a plastic-based radiation-shielding body, a radiation-shielding body thereof, and a radiation shielding apparatus using same. In the present invention, tungsten powder is mixed with plastic resin powder, the tungsten powder is subdivided and mixed stepwise at intervals of 10 to 30 minutes to form a mixture, the mixture is dispersed and extruded at an extrusion temperature of 200 to 220°C to prepare compounding pellets, and the compounding pellets are subjected to injection molding. Thus, by containing high-concentration and highly dispersed tungsten, the present invention provides excellent radiation-shielding efficiency, ensures linearity and rigidity, provides non-clumping properties, and enables manufacture in various shapes and sizes, and thus can be applied to a medical radiation device, or air precision transportation equipment.

Classes IPC  ?

• G21F 1/10 - Substances organiquesDispersions dans des supports organiques
• G21F 5/00 - Récipients blindés portatifs ou transportables
• B29C 45/00 - Moulage par injection, c.-à-d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule ferméAppareils à cet effet
• B29L 31/30 - Véhicules, p. ex. bateaux ou avions, ou éléments de leur carrosserie

Abrégé

The present invention relates to a radiation shielding fabric, a method for manufacturing same, and a radiation shielding article using same. The radiation shielding fabric of the present invention is formed of yarn which is obtained by melt-spinning a PET base resin containing barium sulfate, and the fabric itself thus has shielding ability, thereby ensuring durability and reproducibility of shielding performance, and high strength and elasticity is realized so that the radiation shielding fabric can be applied to medical protective cloth for patients, radiation shielding clothing, etc.

Classes IPC  ?

• D03D 15/50 - Tissus caractérisés par la matière, la structure ou les propriétés des fibres, des filaments, des filés, des fils ou des autres éléments utilisés en chaîne ou en trame caractérisés par les propriétés des filés ou des fils
• D03D 1/00 - Tissus conçus pour faire des articles particuliers
• D01F 1/10 - Autres agents modifiant les propriétés de ces filaments
• D01D 5/08 - Méthodes de filage à partir de masses en fusion
• A61B 6/10 - Moyens de sécurité spécialement adaptés à cet effet
• G21F 1/10 - Substances organiquesDispersions dans des supports organiques
• G21F 3/02 - Habillement

Abrégé

The present invention provides a pyrazolopyrimidine sulfonamide derivative represented by chemical formula 1, an isomer thereof, or a pharmaceutically acceptable salt thereof. As the pyrazolopyrimidine sulfonamide derivative of chemical formula 1 according to the present invention has an excellent Wee1 inhibitory activity effect, the derivative may inhibit growth and metastasis of a cancer cell by controlling a cell-division cycle and inhibiting a function of a cancer stem cell, and may be usefully utilized for the prophylaxis or treatment of a cancer-related disease which is a condition in which cancer cells exhibit abnormal proliferation. In addition, the pyrazolopyrimidine sulfonamide derivative according to the present invention may be usefully utilized for the prophylaxis or treatment of a cancer-related disease through combined use with chemotherapy using a chemical anticancer agent, an immune anticancer agent, a targeted therapeutic agent, and the like, or with radiation therapy. [chemical formula 1]

Classes IPC  ?

• C07D 487/04 - Systèmes condensés en ortho
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention relates to a tungsten composite yarn with improved flexibility and shielding performance, a radiation-shielding fabric using same, and a radiation-shielding article. The tungsten composite yarn with improved flexibility and shielding performance of the present invention comprises: a tungsten wire; a first yarn primarily covering the outer circumferential surface of a core yarn while the tungsten wire is used as the core yarn; and a second yarn secondarily covering the outer circumferential surface of the first yarn, and thus provides excellent flexibility and durability, and the tungsten composite yarn can implement high shielding performance through a synergistic effect of two kinds of raw materials disclosed as radiation-shielding materials, and thus is applicable to radiation-shielding medical clothing, fire-fighting clothing, and the like.

Classes IPC  ?

• D02G 3/12 - Fils contenant des filaments ou rubans métalliques
• D02G 3/38 - Fils dans lesquels des fibres, des filaments ou des filés sont entortillés avec d'autres filés ou filaments
• D02G 3/36 - Filés ou fils à âme ou guipés
• D02G 3/04 - Fils provenant de mélange ou autres filés ou fils contenant des composants faits de matières différentes
• D02G 3/44 - Filés ou fils caractérisés par la destination pour laquelle ils ont été conçus
• G21F 3/02 - Habillement
• A62B 17/00 - Vêtements de protection contre la chaleur, les agents chimiques nuisibles ou pour l'emploi à haute altitude

Abrégé

The present invention relates to a device for monitoring the impact of nodes on an Ethereum network and a method for analyzing the impact of nodes on an Ethereum network, wherein the node impact analysis method involves ascertaining the relationship between a node and the performance of the Ethereum network, and determining the impact of a specific node on the Ethereum network by using the path along which a block generated in the node is propagated. Accordingly, the present invention can be used to evaluate the effect of nodes on the performance of the Ethereum network, and detect and prevent malicious security attacks, wherein the evaluation is centered on nodes having a large impact on network performance.

Classes IPC  ?

• H04L 29/08 - Procédure de commande de la transmission, p.ex. procédure de commande du niveau de la liaison
• H04L 12/26 - Dispositions de surveillance; Dispositions de test

Abrégé

According to a cord blood storage service system and method, using purchaser pre-matching, that register ownership information by using blockchain technology, presented in the present invention, biological data is used to match a potential purchaser of cord blood and a pregnant woman before delivery by the pregnant woman, so that storage of the cord blood is processed with money paid by the potential purchaser without payment by the pregnant woman, and thus the storage rate of cord blood, which is an important resource, is increased, cord blood is brokered so that patients requiring the cord blood can purchase the cord blood in a positive and legal method, and blockchain technology is used to issue ownership information of cord blood so that the issued ownership information is registered in the account of a potential purchaser, and thus the ownership information of the cord blood can be safely stored, read, and traded without the guarantee of a third party such as a cord blood bank.

Classes IPC  ?

• G06Q 30/08 - Ventes aux enchères
• G06Q 30/06 - Transactions d’achat, de vente ou de crédit-bail
• H04L 29/08 - Procédure de commande de la transmission, p.ex. procédure de commande du niveau de la liaison
• H04L 29/06 - Commande de la communication; Traitement de la communication caractérisés par un protocole
• G06Q 50/22 - Aide sociale ou assistance sociale, p. ex. activités de développement communautaire ou services de consultation
• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
• G06Q 50/18 - Services juridiques
• G06Q 20/36 - Architectures, schémas ou protocoles de paiement caractérisés par l'emploi de dispositifs spécifiques utilisant des portefeuilles électroniques ou coffres-forts électroniques

Abrégé

Proposed in the present invention is an apparatus and method for manufacturing a thin shielding film through an air pressurization-type tungsten powder filling processing technique using a curved reflection board, the apparatus comprising: a curved reflection board on which a film to be manufactured into the thin shielding film is positioned; a shielding material spray part which disperses tungsten nanopowder toward the front surface of the film positioned on the curved reflection board; and an adhesive resin spray part which disperses an adhesive resin in conjunction with the shielding material spray part in order to safely fix the film. The structure of the curved reflection board and the novel shielding material dispersion technique, in which particles of tungsten nanopowder dispersed while carried by air flow are uniformly dispersed, can ensure the reproducibility of the shielding process according to the processes of the manufacturing process.

Classes IPC  ?

• G21F 1/12 - Matériaux de blindage laminés
• C23C 24/04 - Dépôt de particules par impact
• B05C 5/02 - Appareillages dans lesquels un liquide ou autre matériau fluide est projeté, versé ou répandu sur la surface de l'ouvrage à partir d'un dispositif de sortie en contact, ou presque en contact, avec l'ouvrage
• B05C 13/02 - Moyens pour manipuler ou tenir des objets, p. ex. des objets individuels pour des objets particuliers
• C08J 7/04 - Revêtement
• C08J 5/18 - Fabrication de bandes ou de feuilles

Abrégé

According to a radiation shielding pad made by compressing multiple layers of lattice-structured fiber manufactured using tungsten wires, and a manufacturing method therefor, which are presented in the present invention, tungsten fibers weaved using tungsten wires are overlapped in multiple layers so as to be stacked in a plurality of layers, and the tungsten fibers, which are overlapped in multiple layers so as to be stacked in a plurality of layers, are compressed to form one radiation shielding pad, and thus are woven into fibrous tissue so that shielding performance can be adjusted by means of the layers of fiber during low-dose radiation shielding, and ventilation is possible to enable wearing at all times in a low-dose radiation area.

Classes IPC  ?

• G21F 1/12 - Matériaux de blindage laminés
• G21F 3/025 - Vêtements entourant complètement l'utilisateur
• A41D 31/04 - Matériaux spécialement adaptés aux vêtements de dessus caractérisés par une fonction ou une utilisation particulières

Abrégé

The present invention relates to biopsy forceps. The biopsy forceps according to the present invention comprise: a tongs-assembly part having the form of tongs so as to be able to collect internal body tissue to be tested; a wire assembly part having the front end connected to the tongs-assembly part; a handle body part connected to the rear end of the wire assembly part so as to control the operation of the tongs-assembly part; and a balloon tube part having, at the front end, a balloon surrounding the tongs-assembly part. Thus, the biopsy forceps can stably collect internal body tissue.

Classes IPC  ?

• A61B 10/06 - Pinces à biopsie
• A61B 10/04 - Instruments endoscopiques, p. ex. instruments de type cathéther
• A61B 17/295 - Pinces pour la chirurgie faiblement invasive combinées à des instruments coupants
• A61B 17/29 - Pinces pour la chirurgie faiblement invasive
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• A61B 5/283 - Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG] invasives
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

The present invention relates to a micro RNA biomarker for predicting drug response to antidiabetics, and a use thereof. In the present invention, the drug response prediction markers miR-136-3p, miR-150-3p, miR-15a-3p, miR-337-3p, miR-369-3p, miR-376a-3p, miR-379-5p, miR-483-3p, miR-495-3p, and miR-6126 were selected by comparing miRNA profiles of a normal group and a diabetes patient group before and after administering an SGLT2 inhibitor that is an antidiabetic. It was confirmed that the expression patterns of the selected markers differed for the normal group and the diabetes patient group, and that the expression patterns for the diabetes patient group were restored so as to be similar to those for the normal group when the SGLT2 inhibitor that is an antidiabetic was administered to the diabetes patient group. Therefore, the marker according to the present invention may be useful as a marker for predicting drug response to antidiabetics.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique

Abrégé

According to a device and a method for learning time series data on the basis of multilayer random forests, presented in the present invention, candidate regions detected in learning data composed of time series images of a plurality of consecutive frames are connected to create a tube, features are extracted from sub-tubes obtained by dividing the tube, and learning is performed by inputting the feature extracted from each sub-tube into each layer of a time series multilayer random forest classifier including a plurality of layers, thus fast computation speed is provided due to reduced learning parameters that should be maintained and a simple decision-making process, and far more flexible operation is possible than in RNN-based models.

Classes IPC  ?

• G06N 20/00 - Apprentissage automatique

Abrégé

A novel benzoheterocycle compound or a pharmaceutically acceptable salt thereof showed a high anti-proliferative effect against cancer cell lines. Using this, a pharmaceutical composition for preventing or treating cancer disease can comprise the compound or a pharmaceutically acceptable salt thereof as an active ingredient. In addition, a health functional food composition for preventing or improving cancer disease can include the compound or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition or health functional food composition can effectively prevent or treat various cancer diseases.

Classes IPC  ?

• C07D 235/12 - Radicaux substitués par des atomes d'oxygène
• A23L 33/00 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61P 35/00 - Agents anticancéreux
• C07D 263/57 - Radicaux aryle ou aryle substitués
• C07D 277/66 - Benzothiazoles avec uniquement des radicaux hydrocarbonés ou des radicaux hydrocarbonés substitués liés en position 2 avec des cycles ou des systèmes cycliques aromatiques liés directement en position 2

Abrégé

According to a delirium intervention mobile device and delirium intervention system for nursing home personnel proposed in the present invention, a mobile device running an application for nursing home personnel for delirium intervention targeting nursing home subjects is used to provide a predicted delirium risk according to risk factors, a delirium assessment result, and a checklist for delirium intervention, and thus, the nursing home personnel can easily and conveniently monitor delirium and intervene so as to prevent delirium using the application, thereby enabling nursing home personnel to preemptively exercise caution, or preemptive prevention of an onset of delirium, and effectively preventing the risk of a sudden onset of delirium.

Classes IPC  ?

• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G06Q 50/22 - Aide sociale ou assistance sociale, p. ex. activités de développement communautaire ou services de consultation
• G06Q 10/06 - Ressources, gestion de tâches, des ressources humaines ou de projetsPlanification d’entreprise ou d’organisationModélisation d’entreprise ou d’organisation
• G06N 20/00 - Apprentissage automatique

Abrégé

According to an energy-efficient pupil tracking method and device based on the simplification of a cascade regression forest proposed in the present invention, a lightweight cascade coarse-to-fine regression forest (CCD-RF) is generated by applying a rule distillation according to feature importance-based rule contribution to an initial CCD-RF which is composed of a cascade multilayer using a plurality of regression forests and has been trained on pupil position using a coarse-to-fine method, and the lightweight CCD-RF is used to predict pupil position from an image. Thus, the number of parameters and the amount of calculations can be reduced and energy consumption can be minimized while maintaining strong performance through the removal of unnecessary rules.

Classes IPC  ?

• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• G06K 9/48 - Extraction d'éléments ou de caractéristiques de l'image en codant le contour de la forme
• G06N 20/00 - Apprentissage automatique

Abrégé

According to a motor using asymmetric stator shoes and a manufacturing method therefor, present in the present invention, the motor comprises: a stator having a stator core in which a coil is wound around a cylindrical stator body; and a rotor, which is arranged inside the stator and rotates, has a shaft hole formed at the center thereof into which a rotary shaft can be pressed and inserted, and has a plurality of permanent magnets that are arranged on a rotor core and that are arranged in a radial shape from the rotating center so as to have a rotational radius, wherein the stator is formed so that the lengths of stator shoes, which are bent on both sides at the end of the stator core and extend, are imbalanced and different from each other, thereby reducing torque ripples and cogging torque that indispensably increase during design for increasing the power of rotational machinery, and thus the motor can be stably operated with minimized vibration and noise.

Classes IPC  ?

• H02K 1/14 - Noyaux statoriques à pôles saillants
• H02K 1/27 - Noyaux rotoriques à aimants permanents
• H02K 1/02 - Détails du circuit magnétique caractérisés par le matériau magnétique
• H02K 21/14 - Moteurs synchrones à aimants permanentsGénératrices synchrones à aimants permanents avec des induits fixes et des aimants tournants avec des aimants tournant à l'intérieur des induits
• H02K 15/03 - Procédés ou appareils spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation des machines dynamo-électriques des corps statoriques ou rotoriques comportant des aimants permanents

Abrégé

According to an electrocardiogram system and an electrocardiogram method proposed in the present invention, a long wire connected from a central unit to an electrode is eliminated and thus the problem of twisting or tangling of the wire can be resolved; and a small-sized mobile and portable wireless communicator is used and thus electrocardiogram can be simply and easily measured without needing to move a large and complex central unit.

Classes IPC  ?

• A61B 5/30 - Circuits d’entrée à cet effet
• A61B 5/282 - Supports pour électrodes multiples
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p. ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
• A61B 90/92 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes utilisant des codes de couleurs

Abrégé

According to a micro tungsten-based radiation shielding paper and a method for manufacturing same, provided by the present invention, a tungsten powder is molded in a particle dispersion manner into a shielding sheet; and the formed shielding sheet is thermally treated and then formed into a film type of highly densely charged paper through a cutting and molding process, whereby not only can a maximum radiation shielding effect be brought about without using lead harmful to the human body and the environment, but processing can also be freely and easily performed through a ultra-light and ultra-thin tungsten paper composed based on the sole material of tungsten.

Classes IPC  ?

• G21F 1/08 - MétauxAlliagesCermets, c.-à-d. mélanges frittés de céramiques et métaux
• G21F 1/12 - Matériaux de blindage laminés

Abrégé

The present invention relates to a whitening composition comprising a plum seed extract as an active ingredient, and more specifically, provides a skin-whitening cosmetic composition, a health food composition, and a composition for preventing or treating skin conditions caused by overproduction of melanin, each of which comprises a plum seed extract as an active ingredient. The plum seed extract according to the present invention has more stable and superior tyrosinase inhibitory activity compared to the ascorbic acid conventionally used as a whitening material, and thus can be used as a functional cosmetic material for skin whitening and can effectively prevent or treat abnormal skin pigmentation disorders such as liver spots, freckles, and sunspots.

Classes IPC  ?

• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A61K 36/736 - Prunus, p. ex. prune, cerise, pêche, abricot ou amande
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques

Abrégé

According to an automatic neck pillow dedicated to cervical spine rehabilitation exercise and a method of using same proposed in the present invention, the automatic neck pillow is configured to support a user's cervical spine through a cervical spine support formed in a central portion of a neck pillow body, and is configured to enable rolling massage of the user's cervical spine through a rolling device inserted and mounted inside wing extensions extending from both sides of the cervical spine support, such that it is possible to fix the cervical spine regardless of the shape of the cervical spine and the positions of the head and the shoulders in a posture of a normal positon of the body and a posture when lying on the side.

Classes IPC  ?

• A47G 9/10 - Oreillers ou traversins
• A61H 1/02 - Appareils d'exercice extenseurs ou de ployage
• A61H 1/00 - Appareils pour l'exercice passifAppareils vibrateursDispositifs de chiropractie, p. ex. dispositifs pour appliquer des chocs au corps, dispositifs externes pour étirer ou aligner de façon brève des os non fracturés
• A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux

Abrégé

According to an optical coherence tomography brain catheter for intracerebrovascular surgery and a method for using same, proposed in the present invention, the optical coherence tomography brain catheter comprises: a catheter distal portion including a distal non-braided OCT lens catheter for imaging an intracerebral vessel and a distal braided catheter integrally connected to the distal non-braided OCT lens catheter; a catheter proximal portion including a proximal braided catheter integrally connected to the distal braided catheter of the catheter distal portion and a proximal shaft integrally connected to the proximal braided catheter; and a microwire for guiding the direction in which the catheter distal portion inserted into a blood vessel travels along the blood vessel. Therefore, unlike the structure of the existing heart OCT catheter, the brain catheter can have improved exploration and propulsion for reaching a multifolded brain blood vessel and can minimize the interference of an optical coherence tomography for intracerebrovascular surgery.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61M 25/00 - CathétersSondes creuses
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

Abrégé

The present invention relates to a biomarker for early diagnosis of diabetes or diabetic complications, and use thereof and, more specifically, to an ADAM2 biomarker for early diagnosis of diabetes or diabetic complications, a composition for early diagnosis of diabetes or diabetic complications using the biomarker, a diagnostic kit, and a method for providing information necessary for early diagnosis of diabetes or diabetic complications. The ADAM2 biomarker for early diagnosis of diabetes or diabetic complications of the present invention was confirmed to have a specifically reduced expression level in the pre-diabetes stage, compared to normal subjects, and a pattern was confirmed in which the expression thereof was further increased in diabetic retinopathy and diabetic nephropathy, which are diabetic complications, as compared to normal or diabetic subjects, and thus the biomarker can be useful for early diagnosis of diabetes or diabetic complications.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• G01N 33/53 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet
• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique

Abrégé

The present invention relates to a novel Bacillus velezensis WK2019 strain and a milk fermentate using same. More specifically, the Bacillus sp. Bacillus velezensis WK2019, which is isolated from kimchi, was found to allow the provision of a milk fermentate that has a better flavor than those fermented with conventional Bacillus spp., and exhibits an increased GABA content and an anti-thrombotic effect. As such, the milk fermentate using the strain can be provided as a functional food.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• A23C 9/12 - Préparations à base de lait fermentéTraitements utilisant des micro-organismes ou des enzymes
• C12R 1/07 - Bacillus

Abrégé

22O for the hydrolysis of silane is mixed with a solvent; (b) adding, to the mixed solution prepared in step (a), a weakly basic substance as a catalyst for causing the polymerization reaction of silane; and (c) adding, to the mixed solution synthesized in step (b), [3-(methacryloyloxy)propyl]trimethoxysilane silane, which is a precursor of polysilsesquioxane.

Classes IPC  ?

• C08G 77/06 - Procédés de préparation
• C08G 77/08 - Procédés de préparation caractérisés par les catalyseurs utilisés
• C08G 77/18 - Polysiloxanes contenant du silicium lié à des groupes contenant de l'oxygène à des groupes alcoxyle ou aryloxyle

Abrégé

An electronic device according to various embodiments may comprise: a memory for storing instructions; and a processor connected to the memory. The processor may be configured to: acquire image data captured by using a camera; calculate a heart rate value by analyzing the image data; determine whether or not the heart rate value has been normally acquired; when the heart rate value has not been normally acquired, determine a correction value for a section in which the heart rate value has not been normally acquired; and store, in the memory, biometric data including the correction value.

Classes IPC  ?

• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A63B 24/00 - Commandes électriques ou électroniques pour les appareils d'exercice des groupes
• A63B 71/06 - Dispositifs indicateurs ou de marque pour jeux ou joueurs

Abrégé

According to a photobiomodulation method and system for inducing the activity of a brain-derived nerve growth factor in a hippocampal tissue, proposed by the present invention, a photobiomodulation (PBMT or PBM) method, which is a therapy using infrared to near-infrared (wavelength of 600-1100 nm) light, is utilized, thereby delaying the death of cells, promoting the proliferation of meristematic cells, and inducing natural treatment without the risk of adverse reactions to a disease or lesion, in a simple and easy manner in which low-level laser light is irradiated into a living body, based on the principle that certain molecules in the living body can absorb photons and trigger signaling pathways in response to light of a specific wavelength band.

Classes IPC  ?

• A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
• A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose

Abrégé

The present invention relates to a device for providing health state information using blood metabolism, and to a method therefor. According to the present invention, the device for providing health state information using blood metabolism comprises: a measurement unit which measures blood glucose and blood lactate values in a subject to be measured; a calculation unit which calculates a blood metabolism value by using the measured values; and a control unit which determines, by using the measured glucose value and the calculated metabolism value, a health state of the subject to be measured, and provides health state information corresponding to the determined result. According to the present invention, by calculating the blood metabolism value through measuring the amount of glucose and lactate in blood, and by providing health state information corresponding to the calculated result, the emergence of obesity and obesity-associated diseases, such as hyperlipidemia, can be diagnosed at an early stage.

Classes IPC  ?

• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang

Abrégé

A method for predicting the likelihood of developing lung cancer by using an artificial intelligence model comprises the steps of: receiving, by means of an analysis device, a chest fluorodeoxyglucose (FDG) PET/CT image for a sample; inputting, by means of the analysis device, the F-18 FDG PET/CT image to a first classification neural network, and outputting prediction information related to development of lung cancer for the sample; and predicting, by means of the analysis device, a likelihood of developing lung cancer for the sample on the basis of the prediction information. The first classification neural network is trained by using chest F-18 FDG PET/CT images for healthy people and training images excluding lung cancer regions from chest F-18 FDG PET/CT images for lung cancer patients.

Classes IPC  ?

• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• G06N 3/02 - Réseaux neuronaux
• A61B 6/03 - Tomographie informatisée
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux

Abrégé

According to a system and method for a no-cost cord-blood banking service using buyer pre-matching, as proposed in the present invention, bio-data is used to match a pregnant woman with a potential cord blood buyer prior to giving birth, and by processing banking of cord blood with costs borne by the potential buyer and without any expenses from the side of the pregnant woman, the cost burden for banking cord blood on the side of the pregnant woman and family is reduced, thereby increasing the banking rate of cord blood which is an important resource, and acting as an intermediary such that cord blood may be purchased by a patient who needs cord blood through a positive and legal method.

Classes IPC  ?

• G06Q 50/22 - Aide sociale ou assistance sociale, p. ex. activités de développement communautaire ou services de consultation
• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G06Q 30/08 - Ventes aux enchères
• G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p. ex. pour des analyses d’échantillon de patient
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
• G06Q 50/18 - Services juridiques

Abrégé

Proposed in the present invention are a device for removing thrombi in varicose veins using a thrombus collecting mesh and a thrombus suction catheter, and a method for using same, the device comprising: a guide delivery tube which is provided with a guide wire that passes through lesions in the vein obstructed by thick thrombi, and ascends to a normal area of the vein to be mounted thereto; a sheath which is guided along the guide delivery tube and mounted to an appropriate blood vessel position for removing the thrombi in the vein; a thrombus collecting mesh which is mounted to the catheter inserted into the sheath, and passes through the thrombi and spreads out in the normal area of the blood vessel; and a suction catheter which is inserted into the sheath and suctions the thrombi collected in the thrombus collecting mesh. Accordingly, the thrombi in the vein obstructed by the thick thrombi can be easily removed without depending on the skill of a clinician.

Classes IPC  ?

• A61B 17/221 - Dispositifs de préhension des calculs en forme de boucles ou de paniers
• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
• A61M 1/00 - Dispositifs de succion ou de pompage à usage médicalDispositifs pour retirer, traiter ou transporter les liquides du corpsSystèmes de drainage

Abrégé

According to a medical education system capable of observing the structure, function, and mutation of a blood vessel through an implantable biometric signal sensor, proposed in the present invention, it is possible to provide not only theoretical knowledge about a blood vessel, but also biometric information of the structure, function, and mutation of the blood vessel, and blood pressure and body temperature in real time, by using data received from the biometric signal sensor that can be implanted in a body, and it is possible to aid learning of human anatomy. By providing a user with an image of the state of the blood vessel in real time, it is possible to induce interest of the user and induce more active use of the medical education system.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
• A61B 5/026 - Mesure du débit sanguin
• A61B 5/01 - Mesure de la température de parties du corps
• G06Q 50/20 - Éducation
• G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p. ex. dispositif en vraie grandeur pour la démonstration pour la médecine

Abrégé

According to a method and a device for detecting, in real time, a pupil position for a low specification environment system, presented in the present invention, pupil candidate areas for left and right eyes are estimated by applying fast radial symmetry transform (FRST) in an input eye image for fast pupil detection, the pupil candidate areas include an incorrect area due to noise such as reflected light or eyelashes in an image so that spatiotemporal similarity between left and right pupils is extracted in order to effectively exclude the incorrect area and estimate an optimal pupil position, and optimal left and right eye pupil positions are determined using the similarity, thereby excluding algorithms such as deep learning in order to achieve high speed processing, and using an optimized image processing algorithm so as to accurately detect positions of pupils for various pupil positions, changes in lighting brightness, partial blocking and a subject wearing glasses.

Classes IPC  ?

• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• G06K 9/46 - Extraction d'éléments ou de caractéristiques de l'image
• G06K 9/48 - Extraction d'éléments ou de caractéristiques de l'image en codant le contour de la forme

Abrégé

Presented in the present invention are a contactless PPG signal measurement system using a camera, and an operating method therefor, which use a feature in which the correlation between the strength of an optical signal in an image captured by the camera and subcutaneous reflectivity according to a change in a blood flow rate of a subject of whom the heart rate is to be measured, and thus can reduce a conventional inconvenience in which the subject of whom the heart rate is to be measured must wear a device for heart rate measurement during body contact, can very easily and simply measure the heart rate in an unrestrained state, and can measure the heart rate only while the subject of whom the heart rate is to be measured stands in the front of the camera for a moment, thereby reducing inconvenience in the use of a heart rate measurement system.

Classes IPC  ?

• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale

Abrégé

According to a virtual hand illusion system for treatment of hemiplegia patients by using brain stimuli and an operation method therefor, proposed in the present invention, a head mounted display (HMD) device is used in combination with conventional mirror therapy to allow the user to enter a flow state in a virtual reality (VR) or augmented/mixed reality (MR) circumstance and to undergo rehabilitation in more comfortable postures, thereby maximizing the effect of misunderstanding the motion of a non-paralyzed limb as that of a paralyzed limb and throwing brain cognitive function into confusion to reduce pain that may be generated during rehabilitation. In this condition, the patient is subjected to rehabilitation while seeing only motion images on the display without looking his or her real paralyzed limb. In a flow state enhanced to the same degree, thus, the patient can receive rehabilitation therapy and ultimately the time taken for rehabilitation of hemiplegia patients can be reduced.

Classes IPC  ?

• A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscienceDispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p. ex. pour mettre en état d'hypnose
• A61B 5/0476 - Electro-encéphalographie
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G16H 20/70 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mentales, p. ex. la thérapie psychologique ou le training autogène

Abrégé

The present invention relates to peptides isolated from a protein hydrolysate of Tenebrio molitor mealworm and a composition comprising same as an active ingredient for prevention or treatment of liver injury. According to the present invention, a protein hydrolysate of Tenebrio molitor mealworm contains biologically active peptides having a size of 1 kDa or less, reduces the generation of reactive oxygen species, and increases the expression and activity of antioxidative enzymes, thereby effectively protecting hepatocytes from oxidative stress. Thus, the peptide can be advantageously used in a composition for prevention or treatment of liver injury, a health food composition for prevention or alleviation of liver injury, a health food composition for protection of the liver, an anti-oxidative health food composition, and so on.

Classes IPC  ?

• C07K 5/06 - Dipeptides
• C07K 5/062 - Dipeptides la chaîne latérale du premier amino-acide étant acyclique, p. ex. Gly, Ala
• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A23L 33/18 - PeptidesHydrolysats de protéines
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
• A61K 38/00 - Préparations médicinales contenant des peptides

Abrégé

According to a field-wound motor generator using a PM-ASSIST structure, proposed in the present invention, a field-wound motor generator having a stator and a rotor can be configured, wherein, as an improved structure in which a rotor coil and an auxiliary magnet are sequentially wound and arranged on the rotor is configured, the magnetic flux of a field magnet can be increased or demagnetized by means of transition of the direction in which power is applied to the rotor coil of the rotor comprising the auxiliary magnet, and the range of operational capacity can be secured accordingly.

Classes IPC  ?

• H02K 19/16 - Génératrices synchrones
• H02K 1/02 - Détails du circuit magnétique caractérisés par le matériau magnétique
• H02K 1/12 - Parties fixes du circuit magnétique
• H02K 15/00 - Procédés ou appareils spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation des machines dynamo-électriques
• H01F 1/053 - Alliages caractérisés par leur composition contenant des métaux des terres rares
• H01F 1/057 - Alliages caractérisés par leur composition contenant des métaux des terres rares et des métaux de transition magnétiques, p. ex. SmCo5 et des éléments IIIa, p. ex. Nd2Fe14B
• H01F 1/10 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriésEmploi de matériaux spécifiés pour leurs propriétés magnétiques en matériaux inorganiques caractérisés par leur coercivité en matériaux magnétiques durs substances non métalliques, p. ex. ferrites

Abrégé

According to an IOT-based smart system for assisting infant bathing and a control method therefor proposed by the present invention, the system comprises: an infant bathing assisting device for measuring the temperature of bath water for bathing an infant, measuring the quality of the bath water, and measuring the movement of the infant; and a user device linked to the infant bathing assisting device to monitor a bathing state of the infant and a state of water in a bathtub. Through the configuration, a protector can monitor the bathing state of the infant and the state of water in the bathtub anywhere in a house in real time, and can confirm whether the infant is safe, while the infant has a fun and pleasant bath.

Classes IPC  ?

• G06Q 50/10 - Services
• G06Q 50/22 - Aide sociale ou assistance sociale, p. ex. activités de développement communautaire ou services de consultation
• A47K 3/024 - Baignoires spécialement adaptées à un usage particulier, p. ex. pour le lavage des pieds, pour prendre un bain en position assise spécialement adaptées pour les enfants ou les bébés

Abrégé

According to a system for monitoring a chronic heart failure state by using a chest tissue resistance value, and a method for using same proposed in the present invention, a chest tissue resistance measurement device including a resistance measurement unit, a signal processing unit, and a transmission unit is configured to be able to measure and monitor a chest tissue resistance value which decreases as a precursor to the reaching of the pulmonary capillary closing pressure and body fluid overload in a chronic heart failure patient. Thus, the state of disease in a chronic heart failure patient can be monitored in real time, and action can be taken according to the state.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/053 - Mesure de l'impédance ou de la conductivité électrique d'une partie du corps
• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients

Abrégé

The present invention relates to a calculus removal device comprising: an endoscope unit in which a camera is provided at the tip of an endoscope tube inserted along an internal organ or body cavity and captures images inside the internal organ or body cavity, and which outputs the captured images through a monitor; and a calculus removal unit which is inserted along the inside of the endoscope tube of the endoscope unit and selectively removes calculus. A scale ruler for estimating the size of the calculus using augmented reality is provided in a guide tube, basket, or crushing probe of the calculus removal unit, or on a screen of the monitor. Since the scale ruler can be used to estimate the size of the calculus through an endoscope prior to capturing the calculus, the time for a calculus removal procedure is reduced, and calculus removal is easy.

Classes IPC  ?

• A61B 17/221 - Dispositifs de préhension des calculs en forme de boucles ou de paniers
• A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
• A61B 10/06 - Pinces à biopsie
• A61B 10/04 - Instruments endoscopiques, p. ex. instruments de type cathéther
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

The present invention provides a fermented jujube having an increased content of γ-aminobutyric acid (hereinafter referred to as GABA) by using complex fermentation and a preparation method therefor. More particularly, a method for preparation of fermented jujube having an increased content of GABA according to the present invention comprises the steps of: preparing a jujube extract; adding and mixing the jujube extract with fermentative sugars and a yeast extract; inoculating a first starter into the mixture to conduct primary fermentation; and adding monosodium glutamate (MSG) to the primarily fermented product and inoculating a second starter to the primarily fermented product to conduct secondary fermentation. The preparation method utilizes the complex fermentation of lactic acid bacteria and lactic acid bacteria, or yeast and lactic acid bacteria to effectively prepare fermented jujube having an increased content of GABA. The fermented jujube prepared according to the method has an increased content of GABA and as such, can be used in health functional foods or functional beverages.

Classes IPC  ?

• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés

Abrégé

According to a system and method for topology investigation in a block-chain network proposed by the present invention, a topology analysis server receives data of a block-chain network and an active node, retrieved by an investigation client in the block-chain network, and updates an off-line topology model, so that it is possible to continuously investigate the topology of the block-chain network, and thereby evaluate the performance of the block-chain network and understand the robustness and security of the network.

Classes IPC  ?

• H04L 29/08 - Procédure de commande de la transmission, p.ex. procédure de commande du niveau de la liaison
• H04L 12/26 - Dispositions de surveillance; Dispositions de test