Produits et services

education; training; entertainment services; education, namely, secondary education, higher education, postgraduate education; sports and cultural activities. services of engineers and scientists; providing evaluations, estimates, research and reports in the fields of science and technology; scientific research services for medical purposes; clinical studies; architectural and urban planning services.

Produits et services

Education services in the nature of courses at the university level; Providing courses of instruction at the graduate level; Providing courses of instruction at the high school level; Providing information relating to organizing community sporting and cultural activities, contests and games Design and development of computer hardware and software; Industrial research in the field of engineering, automotive systems, computer systems, industrial mechanics; Scientific and technological services, namely, research and design in the field of engineering, medical, biological and social sciences; Scientific and technological services, namely, medical, laboratory, and technological and scientific research in the field of engineering, medical, physical, mathematical and biological sciences

Produits et services

(1) Education and training in the fields of engineering and technology; Education services in the nature of courses at the high school level, college level and university level; Arranging and conducting of educational seminars in the fields of engineering and technology; Educational services, namely, conducting conferences in the fields of engineering and technology; Educational research services; Online publication of non-downloadable electronic books, textbooks, education manuals; Advisory and consultancy services relating to university and postgraduate education in the fields of engineering and technology; Conducting educational conferences, education courses, webinars, workshops and seminars in the fields of engineering and technology; Design of educational courses, examinations and qualifications, namely developing education courses, examinations and professional qualifications standards in the fields of engineering and technology.

Abrégé

The present invention relates to a veterinary composition to be used in the treatment, control and prevention of a disease in an animal, wherein the veterinary composition comprises a mixture of peptides and at least one veterinarily acceptable carrier or adjuvant, wherein the mixture of peptides in turn comprises a complete human ubiquitin (Ub) monomer, a human ubiquitin monomer variant lacking two terminal glycines (Ub(-GG)) and at least one low molecular weight human peptide.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 37/02 - Immunomodulateurs

Abrégé

A purpose of the present invention is to provide a peptide composition having immunomodulating effects for immunotherapy, the peptide content of which does not vary according to cellular origin, and a production method. For this purpose, a peptide composition with immunomodulating effects has been invented, which comprises a complete human ubiquitin (Ub) monomer and a human ubiquitin monomer variant lacking two terminal glycines (Ub(−GG)). The peptide composition for immunotherapy may also comprise at least one fragment of the following human proteins: ankyrin-1, protein 4.1, haemoglobin subunit alpha, haemoglobin subunit beta, haemoglobin subunit delta, complement protein C3, calpastatin, alpha-synuclein, fibrinogen alpha chain, cytoplasmic actin 1, thymosin beta-4, thymosin beta-10 or zyxin.

Classes IPC  ?

• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
• A61P 37/02 - Immunomodulateurs

Produits et services

Vitamins; Dietary food supplements; Food supplements; Health food supplements; Vitamin supplements

Produits et services

Vitamins; Dietary food supplements; Food supplements; Health food supplements; Vitamin supplements

Produits et services

Pharmaceuticals; Dietary supplements for human beings and animals; Food supplements; Medicated food supplements; Mineral dietary supplements; Food supplements for non-medical purposes; Dietary supplements for animals. Advertising services provided via the internet, in relation to the following services: Marketing of naturopathic goods; Distribution wholesale, Retail services, and Selling via worldwide computer networks in relation to the following goods: pharmaceuticals, Dietary supplements for human beings and animals, dietary food supplements, Medicinal food supplements, Mineral food supplements, Food supplements for non-medical purposes, Dietary supplements for animals.

Produits et services

Pharmaceuticals; Dietary supplements for human beings and animals; Food supplements; Medicated food supplements; Mineral dietary supplements; Food supplements for non-medical purposes; Dietary supplements for animals. Advertising services provided via the internet, in relation to the following services: Marketing of naturopathic goods; Distribution wholesale, Retail services, and Selling via worldwide computer networks in relation to the following goods: pharmaceuticals, Dietary supplements for human beings and animals, dietary food supplements, Medicinal food supplements, Mineral food supplements, Food supplements for non-medical purposes, Dietary supplements for animals.

Abrégé

A purpose of the present invention is to provide a peptide composition having immunomodulating effects for immunotherapy, the peptide content of which does not vary according to cellular origin, and a production method. For this purpose, a peptide composition with immunomodulating effects has been invented, which comprises a complete human ubiquitin (Ub) monomer and a human ubiquitin monomer variant lacking two terminal glycines (Ub(-GG)). The peptide composition for immunotherapy may also comprise at least one fragment of the following human proteins: ankyrin-1, protein 4.1, haemoglobin subunit alpha, haemoglobin subunit beta, haemoglobin subunit delta, complement protein C3, calpastatin, alpha-synuclein, fibrinogen alpha chain, cytoplasmic actin 1, thymosin beta-4, thymosin beta-10 or zyxin.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 37/02 - Immunomodulateurs

Abrégé

Described herein are methods of epigenetic modification of fungi and uses thereof. Also described herein are compounds that can have antileishmanial activity and formulations thereof. Also described herein are methods of treating leishmanial infection in a subject that include the step of administering a compound or formulation thereof described herein to the subject.

Classes IPC  ?

• A61K 31/366 - Lactones ayant des cycles à six chaînons, p. ex. delta-lactones
• A61P 33/02 - Antiprotozoaires, p. ex. pour le traitement de la leishmaniose, de la trichomonase, de la toxoplasmose
• C12N 1/14 - ChampignonsLeurs milieux de culture
• C12P 17/18 - Préparation de composés hétérocycliques comportant O, N, S, Se ou Te comme uniques hétéro-atomes du cycle contenant plusieurs hétérocycles condensés entre eux ou condensés avec un système carbocyclique commun, p. ex. rifamycine

Abrégé

The present invention relates to a device that converts mechanical energy provided by a generator of external movement into hydraulic energy. This energy is used to displace a fluid through a pipe connected to flanges of the pump. The pump can be used in different areas in industry, such as the pharmaceutical, food, biomedical, agriculture, mechanical, construction, transport and mining industries, etc.This is because of its versatility for transferring mechanical energy to fluids of different viscosities, with dosing proportional to the angular displacement of the drive shaft. The movement of the movement generator is transferred inside the device by means of a rotor shaft with a single arrangement of magnetic elements provided with magnetic shields. The pump solves the technical problems involved in the use of mechanical seals, such as: contamination of working fluid; mechanical seal failure because of shaft misalignment, causing leaks; and mechanical seal failure because of contact face breakage, causing the fluid to leak to the exterior.

Classes IPC  ?

• F04C 2/12 - Machines ou pompes à piston rotatif du type à engrènement extérieur, c.-à-d. avec un engagement des organes coopérants semblable à celui d'engrenages dentés d'un autre type qu'à axe interne
• F04C 2/14 - Machines ou pompes à piston rotatif du type à engrènement extérieur, c.-à-d. avec un engagement des organes coopérants semblable à celui d'engrenages dentés d'un autre type qu'à axe interne avec des pistons rotatifs dentés
• F04C 2/18 - Machines ou pompes à piston rotatif du type à engrènement extérieur, c.-à-d. avec un engagement des organes coopérants semblable à celui d'engrenages dentés d'un autre type qu'à axe interne avec des pistons rotatifs dentés à formes de dents semblables
• F04C 13/00 - Adaptations des "machines" ou pompes pour utilisation particulière, p. ex. pour très hautes compressions
• F04C 15/00 - Parties constitutives, détails ou accessoires des "machines", des pompes ou installations de pompage non couverts par les groupes
• F16H 49/00 - Autres transmissions
• F16D 27/01 - Embrayages actionnés magnétiquementLeur commande ou leurs circuits électriques à aimants permanents
• H02K 1/22 - Parties tournantes du circuit magnétique
• H02K 1/27 - Noyaux rotoriques à aimants permanents
• H02K 1/28 - Moyens de montage ou de fixation des parties magnétiques tournantes sur ou aux structures constituant le rotor
• H02K 49/10 - Embrayages dynamo-électriquesFreins dynamo-électriques du type à aimant permanent

Abrégé

The present invention relates to a process implemented by a computer which comprises steps of precise securing, handling and mass measurement by atomic force microscopy (AFM or BioAFM), automatically, of the physical and mechanical properties of various types of samples such as cells or bacteria alone or interacting with nanoparticles, biomolecules and other types of carbon-based nanostructures such as graphene or synthetic particles. The process takes multiple measurements in a single sample that is arranged precisely and automatically continues the process with other samples. At the end, the working area continues with other areas making thousands of nano-indentations in a very short time in a reliable and reproducible manner in order to obtain mass data and obtain quantitative data on the physical-mechanical parameters, making it possible to confirm the measurement and representativeness of the type of material derived from the extraction of the mass physical and mechanical analysis thereof that is obtained from the statistical analysis.

Classes IPC  ?

• G01Q 60/24 - Microscopie à forces atomiques AFM [Atomic Force Microscopy] ou appareils à cet effet, p. ex. sondes AFM
• G01Q 60/36 - Mode statique
• G01Q 10/00 - Dispositions pour le balayage ou le positionnement, c.-à-d. dispositions pour commander de manière active le mouvement ou la position de la sonde
• G01Q 10/04 - Balayage ou positionnement fin
• G01Q 30/20 - Dispositifs ou procédés de manipulation d'échantillons
• G01Q 80/00 - Applications des techniques de sonde à balayage, autres que les techniques SPM

Abrégé

The present invention relates to new chemical compounds of formula (I) with a structure different from nitroimidazoles, and to equally novel uses thereof for the treatment of trichomoniasis, making said compounds useful for application by means of pharmaceutical compositions. Also, the administration of said compounds does not cause adverse side effects in comparison with compounds widely known in the field, such as metronidazole.

Classes IPC  ?

• C07D 311/56 - Benzo [b] pyrannes non hydrogénés dans le carbocycle avec des atomes d'oxygène ou de soufre en positions 2 et 4 sans atome d'hydrogène en position 3
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline

Abrégé

The present invention relates to novel chemical compounds of formula I with a structure different from nitroimidazoles, and to equally novel uses thereof for the treatment of trichomoniasis, making said compounds useful for application by means of pharmaceutical compositions. Also, the administration of said compounds does not cause adverse side effects in comparison with compounds widely known in the field, such as metronidazole.

Classes IPC  ?

• C07D 239/40 - Un atome de soufre lié par une liaison double ou sous forme de radical mercapto non substitué
• A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine

Abrégé

The present invention relates to pharmaceutical compositions that can be used for the treatment of trichomoniasis, which comprise compounds with the chemical structure and which also exhibit a synergic effect and do not have the typical side effects of compositions comprising compounds commonly used in the treatment of this disease, such as metronidazole.

Classes IPC  ?

• C07D 311/56 - Benzo [b] pyrannes non hydrogénés dans le carbocycle avec des atomes d'oxygène ou de soufre en positions 2 et 4 sans atome d'hydrogène en position 3
• C07D 239/40 - Un atome de soufre lié par une liaison double ou sous forme de radical mercapto non substitué
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
• A61P 33/02 - Antiprotozoaires, p. ex. pour le traitement de la leishmaniose, de la trichomonase, de la toxoplasmose

Abrégé

The invention relates to strains of Lactobacillus brevis, LbH2, LbH3, LbH5, LbH9 and LbH13, isolated from the juice of Agave salmiana and the method for the isolation thereof, wherein said strains have bile salt hydrolase (SBH) activity as well as probiotic properties that help to prevent an increase in total cholesterol. The invention also relates to a mixture of strains of Lactobacillus brevis, also known as Lactobacillus brevis mix, which prevents damage to the liver given that it reduces the activity of the serum enzymes, markers of liver damage.

Classes IPC  ?

• C12R 1/24 - Lactobacillus brevis
• A61K 35/74 - Bactéries
• A61P 15/16 - Contraceptifs masculins

Abrégé

4).

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• C12R 1/01 - Bactéries ou actinomycètes
• C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
• C12P 3/00 - Préparation d'éléments ou de composés inorganiques à l'exception du dioxyde de carbone

Abrégé

The present invention relates to a method for producing a transfer factor. The method comprises the following steps: freezing and thawing of peripheral-blood leukocytes, dialysis, tangential ultrafiltration, identification and quantification using high-resolution, molecular-exclusion liquid chromatography, and in vitro biological validation. The resulting product is suitable for medical use.

Classes IPC  ?

• C07K 14/52 - CytokinesLymphokinesInterférons
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique

Abrégé

The present invention relates to a method for producing a transfer factor. The method comprises the following steps: freezing and thawing of peripheral-blood leukocytes, dialysis, tangential ultrafiltration, identification and quantification using high-resolution, molecular-exclusion liquid chromatography, and in vitro biological validation. The resulting product is suitable for medical use.

Classes IPC  ?

• C07K 1/16 - ExtractionSéparationPurification par chromatographie
• C07K 1/36 - ExtractionSéparationPurification par une combinaison de plusieurs procédés de types différents
• C07K 14/52 - CytokinesLymphokinesInterférons

Abrégé

The present invention relates to a method for producing a transfer factor. The method comprises the following steps: freezing and thawing of peripheral‑blood leukocytes, dialysis, tangential ultrafiltration, identification and quantification using high‑resolution, molecular‑exclusion liquid chromatography, and in‑vitro biological validation. The resulting product is suitable for medical use.

Classes IPC  ?

• C07K 14/52 - CytokinesLymphokinesInterférons
• C07K 1/16 - ExtractionSéparationPurification par chromatographie
• C07K 1/36 - ExtractionSéparationPurification par une combinaison de plusieurs procédés de types différents

Abrégé

The invention relates to an optical system designed and manufactured such as to detect and remove spines from nopal pads (Opuntia ficus-indica), by means of a device made up of an arrangement of at least one optical fibre, arranged on the longitudinal axis of a bar, which comprises at least one optical sensor at either end, which are connected to the control unit of the system, powered by a supply system and a laser for detecting the spines, preferably a low-power CW Nd:YAG laser, with a wavelength of 532 nm, which has a power of 10 to 500 mW, the light from said laser being guided through a set of movable mirrors onto the surface of the nopal, such as to scan the surface thereof; and a second high-power Nd:YAG laser, for removing the spines, which has a power of 100 W with a wavelength of 1064 nm reflected through the same positioning system, guaranteeing that the two beams of laser light arrive at the same point.

Classes IPC  ?

• A23N 7/00 - Épluchage ou pelage des légumes ou des fruits

Abrégé

The invention relates to a device for determining the thickness of the epidermis, which is suitable for use in the biological sciences and is based on in vivo transmittance measurements. The structure of the device includes an arrangement of optical fibres, formed by a group of one or more fibres. The two groups of fibres are joined at one end with a characteristic distance equal to the diameter of the fibres, while, at the other end, the groups of fibres are separated, forming two independent groups, the design thereof being such that variations in the thickness of the stratum corneum of 400 μm are not taken into account. The diameters of the fibres are in the range of 100 to 600 μm. One group of fibres is used for lighting, said group being coupled to a visible light source, such as a halogen lamp, an LED or a diode laser, all of which are preferably red (610-670 nm), while the other group, intended for collection, is used to measure the signal transmitted, which signal is processed by a spectrometer.

Classes IPC  ?

• A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic

Abrégé

The invention relates to an automated system for the recognition and control of the removal of spines from prickly pears (Opuntia ficus-indica) in real time, said system combining optical sensors, programmable devices and image-segmentation and -processing techniques. For this purpose, the system uses a telecentric lens placed on a moving belt on which a prickly pear leaf is moved and said lens forms an image on a CMOS optical sensor including an embedded processor which generates images of the prickly pear leaf in RGB format, said images being processed by a firmware. Using segmentation methods, the aforementioned firmware detects the position of the spines and generate a set of coordinates, in order subsequently to control an x, y scanning system, using a path optimisation algorithm, which system makes a pulsed Nd: YAG laser beam hit the spines in order to remove them from the surface of the prickly pear.

Classes IPC  ?

• A23N 7/00 - Épluchage ou pelage des légumes ou des fruits

Abrégé

The invention relates to the industry involved in the manufacture of prosthesis apparatuses for the human body and, more specifically, to the industry involved in the manufacture of visual restoration aiding prostheses. The invention consists of an image encoding system for transcorneal stimulation, formed by a video camera, a processor with digital algorithms, and a device known as an electrical stimulator. The system is characterised in that the processor with digital algorithms receives the encoded image and produces a waveform therefrom, and each waveform produced represents the electrical equivalent of a pixel of the image that stimulates the eye. The waveform is established using the following equations: Polynomial. Start time. End time. VI = -8.3484+2.84852t+0.0636951t2 -O mS 22.8782 mS 0.0135417t3 + 0.000213t4 V2 = 667.98 - 28.4229t - 0.883556t2 + 22.8782 mS 60.5166 mS 0.0482479x3 - 0.00047t4 V3 - 17241.5 - 808.047t + 13.9177t2 - 60.5166 mS 84.7457 mS 0.104432t3 + 0.00028t4

Classes IPC  ?

• A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
• G06T 1/00 - Traitement de données d'image, d'application générale

Abrégé

Laser lancet design for taking blood samples for clinical purposes, the structure of which comprises an active Er: YAG element, with an emission wavelength of 2.94 μm, with a pulse energy of up to 0.5 joules and with a pulse duration which varies between 0.2 and 0.9 milliseconds; said lancet has a positioning system formed by an infrared light-emitting diode with an intensity of 10 mW and a phototransistor sensor, which are situated on both sides of, and are perpendicular to, the main laser beam axis, the purpose of which is to activate the generation of the laser pulse (Er: YAG) when the area of incidence, or the patient's finger, matches the position of the focal distance of a lens which focuses the laser pulse.

Classes IPC  ?

• A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers

Abrégé

The invention relates to a machine designed to remove the spines from the green prickly pear (Opuntia ficus-indica) by means of the use of selective laser ablation techniques, which is characterized in that it comprises a laser guide system constituted by optical elements and a laser head that produces the laser beam for spine removal, said beam reaching the zone of incidence by means of the guide system and the scanning system; the latter is regulated by means of a system for detecting the position of the spines and a control system that has the dual purpose of halting the laser until the spine has been completely removed and issuing the order to continue the sweep until the next spine is detected, and reiterating the process, and also has a nozzle for extracting discarded spines in the form of a powder.

Classes IPC  ?

• A23N 7/00 - Épluchage ou pelage des légumes ou des fruits

Abrégé

This invention comprises improved composting of cane sugar press mud and lignocellulosic materials. The result is a low density humectant substrate (SHBD) for use in agriculture. The process takes place in semi-static biopiles which are homogenized and aerated mechanically. The lignocellulose materials are added in a supplied batch system, in steps and doses which depend on the type of lignocellulosic material and the quality of the required final substrate. Another objective is to provide, within 8 weeks, a material without pathogenic microorganisms nor weeds, with low density (ឬ 0.4 g/ml), high porosity (110%), and high water retention (ᡶ 90%), useful as a substrate in horticulture and forestry production in nurseries and greenhouses; or as a humectant and soil-improving agent in agricultural land and eroded soils. Said substrate has better physical, chemical and biological features for plant nutrition than equivalent substrates uch as peat and coconut fibres.

Classes IPC  ?

• C05F 17/00 - Préparation d’engrais caractérisée par des traitements biologiques ou biochimiques, p. ex. compostage ou fermentation
• C05F 5/00 - Engrais fabriqués à partir de déchets de distillerie ou de sucreries, de mélasses, vinasses ou de déchets ou résidus similaires

Abrégé

The invention relates to a mould for creating specially-designed artificial roughness (18, 19) that is intended for the surface of structures and objects (10) which are submerged in a flow (12) and which are supported by, or buried in a soil that is liable to scour, such as bridge piers and piles, ducts and other elements. The artificial roughness, which is created during the casting of the structures, reduces both the intensity of the secondary flow at the leading edge and the intensity of the wake turbulence, thereby reducing the depth and volume of local scouring that can affect said structures.

Classes IPC  ?

• B29C 33/42 - Moules ou noyauxLeurs détails ou accessoires caractérisés par la forme de la surface de moulage, p. ex. par des nervures ou des rainures
• F15D 1/12 - Action sur l'écoulement des fluides autour de corps formés d'un matériau solide en agissant sur la couche-limite
• E02B 3/04 - Ouvrages, appareils ou procédés pour la protection des berges, des côtes ou des ports
• E02B 17/00 - Iles artificielles montées sur pilotis ou supports similaires, p. ex. plates-formes sur pieds extensiblesProcédés de construction de celles-ci