Compositions, devices and processes related to etching of a very thin layer or fine particles of a metal are disclosed for monitoring a variety of parameters, such as time, temperature, time-temperature, thawing, freezing, microwave, humidity, ionizing radiation, sterilization and chemicals. These devices have capabilities of producing a long and sharp induction period of an irreversible visual change. The devices are composed of an indicator comprising a very thin layer of a metal (e.g., polyester film having an extremely thin, e.g., about one hundred Angstroms layer of aluminum) and an activator, e.g., a reactant, such as water, water vapor, an acid, a base, oxidizing agent or their precursors, which is capable of reacting with the said indicator. The indicator retains its opacity and metallic luster, e.g., silvery white, mirror like finish of aluminum layer for a long time. The activator destroys the indicator layer including the naturally formed oxide layer. The indicator layer does not have a matrix/binder. As the device becomes transparent from being highly opaque, any color, message or image printed under it become visible at a pre-determined time, thus making the device self reading. A sealing tape or large label made from an activator and an indicator can be used for sealing boxes and monitoring self-life of perishables inside it. Ink formulations composed of a metal powder and a proper activator can be used for monitoring several sterilization processes, such as sterilization with steam. When water is used as an activator, a thin layer of metals, such as that of aluminum can be used as steam sterilization or humidity indicator. The process can also be used for making patterns, printing plates, electronic circuits and RFIDs (radio frequency identification devices).
A61L 2/07 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques de la chaleur des gaz chauds de la vapeur
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
A61L 2/28 - Dispositifs pour tester l'efficacité ou l'intégralité de la stérilisation, p. ex. indicateurs qui changent de couleur
C09D 11/037 - Encres d’imprimerie caractérisées par des particularités autres que la nature chimique du liant caractérisées par le pigment
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
2.
TIME-TEMPERATURE INDICATOR BASED ON INCREASED THERMAL REACTIVITY OF A DIACETYLENE UPON MELT RECRYSTALLIZATION
This application relates to a time-temperature indicator based on increased thermal reactivity of diacetylene upon melt recrystallization and a method of making it. A diacetylene is crystallized into a low thermal reactivity phase from a solvent system and converted into a higher thermal reactivity phase and low sensitivity to UV light by melt recrystallization.
B41M 5/28 - Thermographie utilisant des composés thermochromes ou des couches contenant des cristaux liquides, des microcapsules, des colorants blanchissables ou des composés thermodégradables, p. ex. libérant un gaz
C07C 271/12 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec les atomes d'azote des groupes carbamate liés à des atomes d'hydrogène ou à des atomes de carbone acycliques à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
G01K 11/16 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant le changement de couleur, de translucidité ou de réflectance de matériaux organiques
3.
In-Situ Generation of Nucleating Agents for Indicating Devices
A nucleating agent composition, a method of forming the nucleating agent and a device comprising the nucleating agent composition are provided. The nucleating agent comprises a nucleating agent comprises silver halide salt with an average particle size of at least 10 nanometer to no more than 100 microns in a polymeric matrix wherein the polymeric matrix has a viscosity of at least 500 cP to no more than 50,000 cP.
G01K 11/06 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant la fusion, la congélation ou le ramollissement
4.
Materials and methods for extending shelf-life of foods
A food with an extended shelf-life and a method of extending shelf-life of food is provided herein. The extended shelf-life is provided by treating the food with isothiocyanate, a non-aromatic cyclic ketone, a boronic acid, a ligand and their precursors.
A food with an extended shelf-life and a method of extending shelf-life of food is provided herein. The extended shelf-life is provided by treating the food with isothiocyanate, a non-aromatic cyclic ketone, a boronic acid, a ligand and their precursors.
A nucleating agent composition, a method of forming the nucleating agent and a device comprising the nucleating agent composition are provided. The nucleating agent comprises a nucleating agent comprises silver halide salt with an average particle size of at least 10 nanometer to no more than 100 microns in a polymeric matrix wherein the polymeric matrix has a viscosity of at least 500 cP to no more than 50,000 cP.
G01K 11/00 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou
G01K 11/06 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant la fusion, la congélation ou le ramollissement
G01K 11/12 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant le changement de couleur, de translucidité ou de réflectance
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
7.
In-situ generation of nucleating agents for indicating devices
A nucleating agent composition, a method of forming the nucleating agent and a device comprising the nucleating agent composition are provided. The nucleating agent comprises a nucleating agent comprises silver halide salt with an average particle size of at least 10 nanometer to no more than 100 microns in a polymeric matrix wherein the polymeric matrix has a viscosity of at least 500 cP to no more than 50,000 cP.
G01K 11/06 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou utilisant la fusion, la congélation ou le ramollissement
8.
MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS
A food with an extended shelf-life and a method of extending shelf-life of food is provided herein. The extended shelf-life is provided by treating the food with at least one shelf-life extender selected from a group consisting of an isothiocyanate, a non-aromatic cyclic ketone, a boronic acid, a ligand and their precursors.
A food with an extended shelf-life and a method of extending shelf-life of food is provided herein. The extended shelf-life is provided by treating the food with at least one shelf-life extender selected from a group consisting of an isothiocyanate, a non-aromatic cyclic ketone, a boronic acid, a ligand and their precursors.
A food with an extended shelf-life and a method of extending shelf-life of food is provided herein. The extended shelf-life is provided by treating the food with at least one shelf-life extender selected from a group consisting of an isothiocyanate, a non-aromatic cyclic ketone, a boronic acid, a ligand and their precursors.
Compositions, devices and processes related to etching of a very thin layer or fine particles of a metal are disclosed for monitoring a variety of parameters, such as time, temperature, time-temperature, thawing, freezing, microwave, humidity, ionizing radiation, sterilization and chemicals. These devices have capabilities of producing a long and sharp induction period of an irreversible visual change. The devices are composed of an indicator comprising a very thin layer of a metal (e.g., polyester film having an extremely thin, e.g., about one hundred Angstroms layer of aluminum) and an activator, e.g., a reactant, such as water, water vapor, an acid, a base, oxidizing agent or their precursors, which is capable of reacting with the said indicator. The indicator retains its opacity and metallic luster, e.g., silvery white, mirror like finish of aluminum layer for a long time. The activator destroys the indicator layer including the naturally formed oxide layer. The indicator layer does not have a matrix/binder. As the device becomes transparent from being highly opaque, any color, message or image printed under it become visible at a pre-determined time, thus making the device self reading. A sealing tape or large label made from an activator and an indicator can be used for sealing boxes and monitoring self-life of perishables inside it. Ink formulations composed of a metal powder and a proper activator can be used for monitoring several sterilization processes, such as sterilization with steam. When water is used as an activator, a thin layer of metals, such as that of aluminum can be used as steam sterilization or humidity indicator. The process can also be used for making patterns, printing plates, electronic circuits and RFIDs (radio frequency identification devices).
A61L 2/07 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques de la chaleur des gaz chauds de la vapeur
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
A61L 2/28 - Dispositifs pour tester l'efficacité ou l'intégralité de la stérilisation, p. ex. indicateurs qui changent de couleur
C09D 11/037 - Encres d’imprimerie caractérisées par des particularités autres que la nature chimique du liant caractérisées par le pigment
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
Compositions, devices and processes related to etching of a very thin layer or fine particles of a metal are disclosed for monitoring a variety of parameters, such as time, temperature, time-temperature, thawing, freezing, microwave, humidity, ionizing radiation, sterilization and chemicals. These devices have capabilities of producing a long and sharp induction period of an irreversible visual change. The devices are composed of an indicator comprising a very thin layer of a metal and an activator, e.g., a reactant, such as water, water vapor, an acid, a base, oxidizing agent or their precursors, which is capable of reacting with the said indicator. Ink formulations composed of a metal powder and a proper activator can be used for monitoring several sterilization processes, such as sterilization with steam. When water is used as an activator, a thin layer of metals, such as that of aluminum can be used as steam sterilization or humidity indicator.
A61L 2/07 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques de la chaleur des gaz chauds de la vapeur
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des substances chimiques des substances gazeuses, p. ex. des vapeurs
A61L 2/28 - Dispositifs pour tester l'efficacité ou l'intégralité de la stérilisation, p. ex. indicateurs qui changent de couleur
C09D 11/037 - Encres d’imprimerie caractérisées par des particularités autres que la nature chimique du liant caractérisées par le pigment
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
13.
A TIME-TEMPERATURE INDICATOR BASED ON INCREASED THERMAL REACTIVITY OF A DIACETYLENE UPON MELT RECRYSTALLIZATION
This application relates to a time-temperature indicator based on increased thermal reactivity of a diacetylene upon melt recrystallization and a method of making it. A diacetylene is crystallized into a low thermal reactivity phase from a solvent system and converted into a higher thermal reactivity phase and low sensitivity to UV light by melt recrystallization.
B41M 5/28 - Thermographie utilisant des composés thermochromes ou des couches contenant des cristaux liquides, des microcapsules, des colorants blanchissables ou des composés thermodégradables, p. ex. libérant un gaz
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
14.
INDICATING DEVICES BASED ON LATERAL DIFFUSION OF A MOBILE PHASE THROUGH A NON-POROUS STATIONARY PHASE
This invention relates to indicating devices, such as time-temperature indicators based on lateral diffusion of a vapor of a solid and/or liquid mobile phase (e.g., a sublimeable dye or an activator) through a non-porous stationary phase, such as a thin layer of a polymeric material. The lateral diffusion of the mobile phase creates a noticeable boundary in the stationary phase whose movement depends upon processes, such as time and temperature.
Indicating devices based on the counter balancing effect of one parameter with that of others are disclosed. Color changing and self -reading indicating devices, such as a time indicator having essentially no effect of temperature are developed by this method. In diffusion based time-temperature indicating devices, the effect of temperature is lowered by crosslinking the medium of the device. The devices have net activation energy near zero kcal/mole.
G04F 1/00 - Appareils pouvant être mis en marche et arrêtés pour mesurer des intervalles de temps prédéterminés ou choisis à volonté, sans mécanisme moteur, p. ex. sabliers
16.
Freeze, thaw and refreeze indicators based on rapid reactions in the solid state
A freeze indicator, which is preferably a self-activating freeze indicator. The freeze indicator has a substrate with a freeze indicator composition coated thereon wherein the freeze indicator has a liquid diacetylene; and a catalyst or catalyst precursor and a protective cover.
G01K 3/04 - Thermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs moyennesThermomètres donnant une indication autre que la valeur instantanée de la température fournissant des valeurs intégrées par rapport au temps
17.
Personal and area self-indicating instant radiation alert dosimeter
Described is a self-indicating instant radiation dosimeter (1001) for monitoring high energy radiations, such as X-ray. The dosimeter contains a radiation sensitive, color changing, indicating composition (10), e.g., a diacetylene (R—C≡C—C≡C—R′, where R and R′ are substituents groups) or a radiochromic dye, a polymeric binder (20) and optionally a shelf life extender (50) or an activator (40). The radiation sensitive composition (10) changes color instantly when exposed to high energy radiation. The dose is estimated by comparing the color with a color reference chart or more accurately with a spectrophotometer or an optical densitometer. The radiation sensitive composition (10) is protected from low energy radiation such as UV light, by a layer of low energy absorbing materials, such as UV absorbers.
A large number of properties of nanostructures depend on their size, shape and many other parameters. As the size of a nanostructure decreases, there is a rapid change in many properties. When the nanostructure is completely destroyed, those properties essentially disappear. Systems based on changes in properties of nanostructures due to the destruction of nanostructures are proposed. The systems can be used for monitoring the total exposure to organic, inorganic, organometallic and biological compounds and agents using analytical methods.
A large number of properties of nanostructures depend on their size, shape and many other parameters. As the size of a nanostructure decreases, there is a rapid change in many properties. When the nanostructure is completely destroyed, those properties essentially disappear. Systems based on changes in properties of nanostructures due to the destruction of nanostructures are proposed. The systems can be used for monitoring the total exposure to organic, inorganic, organometallic and biological compounds and agents using analytical methods.
B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
Compositions, devices and processes related to etching of a very thin layer or fine particles of a metal are disclosed for monitoring a variety of parameters, such as time, temperature, time- temperature, thawing, freezing, microwave, humidity, ionizing radiation, sterilization and chemicals These devices have capabilities of producing a long and sharp induction period of an irreversible visual change The devices are composed of an indicator comprising a very thin layer of a metal (e g, polyester film having an extremely thin, e g, about one hundred Angstroms layer of aluminum) and an activator, e g, a reactant, such as water, water vapor, an acid, a base, oxidizing agent or their precursors, which is capable of reacting with the said indicator The indicator retains its opacity and metallic luster, e g, silvery white, mirror like finish of aluminum layer for a long time The activator destroys the indicator layer including the naturally formed oxide layer
G01D 5/00 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière
A61L 2/28 - Dispositifs pour tester l'efficacité ou l'intégralité de la stérilisation, p. ex. indicateurs qui changent de couleur
B65C 9/26 - Dispositifs pour appliquer les étiquettes
G01N 19/06 - Recherche par enlèvement de matière, p. ex. test à l'étincelle
G01N 19/10 - Mesure de la teneur en eau, p. ex. par mesure de la variation de la longueur d'un filament hygroscopiqueHygromètres
G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
Described is a multi-sensor radiation dosimeter system with (1) a self-indicating, instant radiation sensor and (2) a conventional radiation sensor for monitoring high energy radiations, such as X-ray, electrons and neutrons. Conventional radiation sensors, such as X-ray film, TLD (Thermoluminescence Dosimeters), RLG (Radioluminescence Glass) and OSL (Optically Simulated Luminescence), are highly sensitive but are not instant. In the event of a dirty bomb, nuclear detonation or a radiological accident, one needs to know the exposure instantly so proper precautions can be taken and medical treatment, if required, can be given to the victim. If a self-indicating instant sensor is one of the sensors, one would know the dose instantly, and dose can be determined with higher accuracy than by the traditional methods. This type of device offers the best of both technologies.
A general purpose high accuracy dosimeter reader, 80, for determination of a treatment condition, based on comparison of an image of treated dosimeter, 111, with a series of images of pre-treated dosimeter, 114, is disclosed. A dosimeter undergoes noticeable changes, such as a color change upon treatment with certain materials, such as toxic gases and processes, such as ionizing radiation and sterilization is pre-treated. The dosimeter is imaged with an imaging device, 115, such as charge-coupled device camera and images of the dosimeter or the changes, e.g., color change, are stored in an information storage device, 118. In order to determine the treatment condition, the treatment dosimeter is imaged and the image is compared with the series of pre-treated images of the dosimeter using software. The closest match of the treated dosimeter with the pre-treated and pre-imaged dosimeter would indicate the treatment conditions. The process and device can be used for almost any indicating device, process and treatment.
A tamper resistant and evident, self indicating instant radiation alert dosimeter (referred to as SIRAD) made by encapsulating a radiation sensing system in a polymeric material is disclosed. SIRAD is made from many layers of polymeric materials by multi-step processes. The radiation sensing system of SIRAD is encapsulated in a polymeric media made by a casting or reaction injection molding process.
A general purpose high accuracy dosimeter reader (80) for determination of dose, based on comparison of a treated dosimeter (111) with a series of images of pre-treated dosimeter (114). A dosimeter undergoes noticeable changes, such as a color change upon treatment with certain materials, such as toxic gases and processes, such as ionizing radiation and sterilization is pre-treated. The dosimeter is imaged with an imaging device (115) and images of the dosimeter or the changes, are stored in an information storage device (118). In order to determine the dose, the treated dosimeter is imaged and the image is compared with the series of pre-treated images of the dosimeter. The closest match of the treated dosimeter with the pre-treated and pre-imaged dosimeter would indicate the dose.
Disclosed is a detector for monitoring a UV false positive from genuine X-ray positive of color developing radiation sensitive devices. A layer which can be scratched off and is opaque to undesired radiation but transparent to X-ray is printed on the sensor. If the sensor displays a signal (i.e., develops color), whether it is genuine or false positive can be confirmed by scratching off the opaque layer. If the signal is a genuine positive, the whole sensor will be uniformly exposed/colored including the area under the opaque layer. If it is a false positive, the area under the scratched off layer will be of lighter color than the rest of the sensor.
