Abrégé

One example relates to a method for providing an immersive virtual golf service using an extended Reality (XR). The method may comprise: capturing an image of an actual golf ball placed on a ground through a camera of an XR device; reproducing and displaying the image within a virtual golf environment displayed on a display unit of the XR device; capturing, in real-time, a golf swing of a user through the camera of the XR device; analyzing a golf swing motion of the user in real-time using an artificial neural network model; and reproducing and displaying the analyzed golf swing motion within the virtual golf environment displayed on the display unit of the XR device.

Classes IPC  ?

• A63B 69/36 - Appareils d'entraînement ou appareils destinés à des sports particuliers pour le golf
• A63B 71/06 - Dispositifs indicateurs ou de marque pour jeux ou joueurs
• G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
• G06N 3/067 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens optiques

Abrégé

The present invention relates to a composition comprising a skin keratinocyte-derived extracellular matrix as an active ingredient as an active ingredient for the prevention, alleviation, or treatment of cancer. The composition for preventing, alleviating, or treating cancer of the present invention contains an extracellular matrix derived from skin keratinocytes as an active ingredient, thereby significantly reducing only the proliferation of cancer cells without exhibiting side effects such as cytotoxicity in normal cells such as fibroblasts constituting the dermis of normal skin. In addition, the composition for preventing, alleviating, or treating cancer of the present invention was observed to: have the effect of suppressing the proliferation of MDA-MB-231, which cannot be expected to be greatly responsive to targeted therapies and currently lacks effective treatments, in addition to MCF7 among breast cancer cells; be able to remarkably inhibit the proliferation of Caki-1 and Caki-2, which are clear cell carcinomas classified as intractable cancer among kidney cancer cells and known to have many distant metastasis recurrences; and significantly reduce the proliferation of PANC-1, which is a pancreatic cancer cell line classified as refractory cancer that is difficult to detect early among cancer cells and is found in the late stage when surgery and treatment are limited, as well as having low treatment responsiveness to the latest immunotherapy drugs and low treatment responsiveness to targeted therapy and traditional chemotherapy. Furthermore, the composition for preventing, alleviating, or treating cancer of the present invention can be applied not only to breast cancer, kidney cancer, and pancreatic cancer, but also to the treatment of various carcinomas and solid cancers occurring on the skin. Moreover, the composition for preventing, alleviating, or treating cancer of the present invention can be used as a therapeutic agent in combination with other anticancer agents. Additionally, the composition for preventing, alleviating, or treating cancer of the present invention can be used in a treatment method for reducing the size of cancer before surgery without side effects, unlike traditional chemotherapy, through intratumoral injection.

Classes IPC  ?

• A61K 35/36 - PeauSystème pileuxOnglesGlandes sébacéesCérumenÉpidermeCellules épithélialesKératinocytesCellules de LangerhansCellules ectodermiques
• A61P 35/00 - Agents anticancéreux
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A23K 10/20 - Produits alimentaires pour animaux à base de matières d’origine animale

Abrégé

T. niT. niT. ni cecropin has the excellent effects of reducing liver and kidney toxicity values, inflammatory cytokine production, and endotoxins and inhibiting inflammatory cell infiltration in animal models infected with LPS-infected endotoxemia and Carbapenem-resistant Acinetobacter baumannii and can thus be effectively used for preventing or treating bacterial infections (e.g., gram-negative bacterial infections), sepsis, or inflammatory diseases.

Classes IPC  ?

• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 31/04 - Agents antibactériens
• A01N 37/46 - Dérivés N-acylés
• A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges

Abrégé

An MXene or a derivative thereof, on which nitrous oxide reductase is immobilized, wherein the MXene has a formula of Mn+1XnTs, wherein M is a transition metal of Groups 3, 4, 5, 6, or a combination thereof, of the Periodic Table of the Elements, X is carbon, nitrogen, or a combination thereof, T is oxide, epoxide, hydroxide, C1-C5 alkoxide, fluoride, chloride, bromide, iodide, or a combination thereof, and n is 1, 2, or 3, and s is 0, 1, or 2.

Classes IPC  ?

• C12N 9/06 - Oxydoréductases (1.), p. ex. luciférase agissant sur des composés contenant de l'azote comme donneurs (1.4, 1.5, 1.7)
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p. ex. nanocomposites
• C01B 32/914 - Carbures d’un seul élément
• C01G 39/00 - Composés du molybdène

Abrégé

Archangium violaceumArchangium violaceum with, as substrates, a high-purity docosahexaenoic acid reagent and polyunsaturated fatty acids obtained through solvent extraction after hydrolysis from low-cost docosahexaenoic acid-enriched oil, and, more specifically, to: a method and a preparation composition therefor, the method being for obtaining docosahexaenoic acid having a purity of 90% through a purification process of using commercial lipase and adsorbent resins to effectively hydrolyze docosahexaenoic acid-enriched oil into polyunsaturated fatty acids, which include docosahexaenoic acid, and then performing solvent extraction thereon; and a method and a preparation composition therefor, the method being for mass-producing resolvin D5, which is a human endogenous substance, in a flask and a bioreactor through whole-cell reactions by using bacteria Archangium violaceum-derived dual arachidonic acid 15-lipoxygenase with, as substrates, a purified hydrolysate and a high-purity docosahexaenoic acid reagent. According to the present invention, the composition can be produced with high productivity and high yield by means of an eco-friendly method, and can be effectively used in various industrial fields such those of medicine, food and cosmetics.

Classes IPC  ?

• C12P 7/6427 - Acides gras polyinsaturés, c.-à-d. ayant plusieurs liaisons doubles dans leur chaîne carbonée
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating depression comprising a Lactobacillus buchneri 200793 strain, and specifically, to a composition for preventing, improving, or treating depression comprising the strain or a culture of the strain, a food composition for alleviating tension, and an animal feed additive composition for preventing or improving depression. When the composition according to the present invention is administered to a subject, sucrose preference is increased, and the expression level of TPH-1 or SERT in small intestine and large intestine tissue is increased, thereby being highly effective in alleviating depression, and thus the composition can be effectively employed for alleviating and improving various symptoms of depression.

Classes IPC  ?

• A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
• A61P 25/24 - Antidépresseurs
• A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
• A23K 10/18 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires de micro-organismes vivants

Abrégé

A nonameric peptide represented by an amino acid sequence of SEQ ID NO: 1 or its enantiomeric peptide thereof according to the present invention is low in cytotoxicity and excellent in terms of proteolytic stability, antimicrobial activity, and anti-inflammatory activity and has a remarkable therapeutic effect on Gram-negative bacterial infectious diseases, sepsis, or septic shock. Accordingly, the peptides can be advantageously applied to an antimicrobial composition, an anti-inflammatory composition, and a pharmaceutical composition for prevention or treatment of Gram-negative bacterial infectious diseases, sepsis, or septic shock.

Classes IPC  ?

• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A61K 38/00 - Préparations médicinales contenant des peptides
• A61P 31/04 - Agents antibactériens

Abrégé

The present invention relates to a food composition using a natural extract for enhancing saltiness. More specifically, a mixing ratio of a shiitake mushroom extract, a lotus root extract and a Chinese cabbage extract, which have high saltiness perceivability, is provided and is used for preparing a double emulsion. The double emulsion prepared according to the present invention has enhanced saltiness while having a stable form, and enables the amount of oil to be reduced, and thus the present invention can be applied to the preparation of various food by using the emulsion.

Classes IPC  ?

• A23L 27/00 - ÉpicesAgents aromatiques ou condimentsÉdulcorants artificielsSels de tableSubstituts diététiques du selLeur préparation ou leur traitement

Abrégé

The present invention relates to a composition, a food composition, a cosmetic composition, and a feed composition for hair loss improvement or hair growth promotion, which contain oat young leaf and/or stem extract, and a pharmaceutical composition and a medical device for prevention or treatment of hair loss disease, which contain oat young leaf and/or stem extract. The present invention relates to a composition, a food composition, a cosmetic composition, and a feed composition for hair loss improvement or hair growth promotion, which contain oat young leaf and/or stem extract, and a pharmaceutical composition and a medical device for prevention or treatment of hair loss disease, which contain oat young leaf and/or stem extract. The oat young leaf and/or stem extract of the present invention has an excellent hair loss improving and hair growth promoting effect by promoting the proliferation of HDP cells and the expression of related genes, and can thus be utilized as medicines, medical devices, feed, foods, health functional foods, cosmetics, and the like that are effective in prevention and treatment of hair loss.

Classes IPC  ?

• A61K 36/899 - Poaceae ou Gramineae (famille des céréales), p. ex. bambou, blé ou canne à sucre
• A61K 8/60 - SucresLeurs dérivés
• A61K 8/9794 - Liliopsida [monocotylédones]
• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 31/728 - Acide hyaluronique
• A61K 38/39 - Peptides du tissu connectif, p. ex. collagène, élastine, laminine, fibronectine, vitronectine, globuline insoluble à froid [CIG]
• A61P 17/14 - Médicaments pour le traitement des troubles dermatologiques pour le traitement de la calvitie ou de l'alopécie
• A61Q 7/00 - Préparations pour modifier la pousse des cheveux ou des poils

Abrégé

The present invention relates to a composition for preventing or treating hair loss, or promoting hair growth or hair nourishment, comprising, as an active ingredient, decellularized extracellular matrix derived from skin keratinocytes. By comprising, as an active ingredient, decellularized extracellular matrix derived from skin keratinocytes, the composition of the present invention significantly promotes the cell proliferation of dermal papilla cells or outer root-sheath cells and increases the expression of genes that regulate hair follicle formation and hair cycle, and thus has an excellent effect of preventing or treating hair loss or on hair growth or hair nourishment. In addition, considering that the dermal papilla cells or the outer root-sheath cells are fibroblasts and keratinocytes of the hair follicle, respectively, the composition of the present invention is expected to be effective not only in hair growth but also in skin wound repair and anti-aging. The decellularized extracellular matrix derived from skin keratinocytes, of the present invention, can be used as a functional ingredient without the risk of immune response and spread of infectious diseases, and is easy to obtain compared to extracellular vesicles or exosomes and can thus be effectively used in medicines, foods, health functional foods, feeds, cosmetics, functional cosmetics, medical devices, and the like.

Classes IPC  ?

• A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
• A61Q 7/00 - Préparations pour modifier la pousse des cheveux ou des poils
• A61Q 5/00 - Préparations pour les soins des cheveux
• A61K 35/36 - PeauSystème pileuxOnglesGlandes sébacéesCérumenÉpidermeCellules épithélialesKératinocytesCellules de LangerhansCellules ectodermiques
• A61P 17/14 - Médicaments pour le traitement des troubles dermatologiques pour le traitement de la calvitie ou de l'alopécie
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A23K 10/20 - Produits alimentaires pour animaux à base de matières d’origine animale

Abrégé

According to one embodiment, the provided resonant converter for an electric vehicle charger comprises: a first input side circuit including a first switching bridge, a first resonance tank and a first primary winding; a second input side circuit which is connected in parallel to the first input side circuit and which includes a second switching bridge, a second resonance tank and a second primary winding; a first output side circuit, which includes a first secondary winding for forming a first transformer together with the first primary winding, and a first rectified network; a second output side circuit which is connected in parallel to the first output side circuit, and which includes a second secondary winding for forming a second transformer together with the second primary winding, and a second rectified network; a switch for connecting the first secondary winding and the second secondary winding; and an output capacitor shared by the first output side circuit and the second output side circuit.

Classes IPC  ?

• H02M 3/00 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu
• H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
• H02M 1/00 - Détails d'appareils pour transformation
• H02M 1/14 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu
• B60L 53/22 - Détails de structure ou aménagements des convertisseurs de charge spécialement adaptés pour recharger des véhicules électriques

Abrégé

The present invention relates to a vector system for cyclizing a target protein. The target protein can be cyclized using a recombinant expression vector according to the present invention, and the optimal conditions for said cyclization have been found. Thus, the present invention has the effect that cyclized target proteins, with a protective effect against proteolytic enzymes in the body and thus a longer half-life and improved stability, can be produced at high yield.

Classes IPC  ?

• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• C07K 14/50 - Facteur de croissance des fibroblastes [FGF]
• C07K 1/16 - ExtractionSéparationPurification par chromatographie

Abrégé

The present invention relates to a vector with increased production efficiency of FGF10 and a vector system for the production of circular FGF10. The circular fibroblast growth factor 10 (FGF10) produced using a vector encoding a fragment of FGF10 or a variant thereof demonstrates higher production efficiency compared to full-length FGF10. Specifically, a recombinant expression vector carrying an intein fragment can circularize FGF10, a fragment thereof, or a variant thereof, resulting in increased stability and half-life compared to linear proteins. The circular FGF10 produced in this manner exhibits a similar level of cell proliferation effect as linear FGF10, while significantly enhancing stability and in vivo half-life.

Classes IPC  ?

• C07K 14/50 - Facteur de croissance des fibroblastes [FGF]
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• B01D 15/36 - Adsorption sélective, p. ex. chromatographie caractérisée par le mécanisme de séparation impliquant une interaction ionique, p. ex. échange d'ions, paire d'ions, suppression d'ions ou exclusion d'ions

Abrégé

A method for producing a solid sodium electrolyte according to an embodiment of the present invention comprises the steps of: (a) preparing sintered bodies for beta-alumina production and powder pellets comprising a sodium source (or powder packs); (b) laminating the sintered bodies and the powder pellets comprising a sodium source (or powder packs) in alternation to prepare a laminate; and (c) heat-treating the laminate to subject the sintered bodies to gas-phase conversion, wherein the powder pellets (or powder packs) may be molded bodies of powder containing a sodium source.

Classes IPC  ?

• C04B 35/113 - Céramiques fines à base d'oxyde d'aluminium bêta
• H01M 10/0562 - Matériaux solides
• H01M 10/054 - Accumulateurs à insertion ou intercalation de métaux autres que le lithium, p. ex. au magnésium ou à l'aluminium

Abrégé

The present invention relates to a fire-extinguishing microcapsule, a method for manufacturing same, and a fire-extinguishing composition comprising same. The microcapsule includes a core containing a non-inflammable material; a first shell layer covering the core and containing inorganic nanoparticles and a water-soluble polymer; and a second shell layer covering the first shell layer and containing a polymer.

Classes IPC  ?

• A62D 1/00 - Compositions pour éteindre les incendiesEmploi de produits chimiques pour éteindre les incendies
• B01J 13/14 - Polymérisation, réticulation

Abrégé

Disclosed are an air purification system using an oil mist and a filter, and a driving method thereof. The air purification system using the oil mist and the filter according to an embodiment of the present application may comprise a first filter module provided to be capable of providing an open state in which the first filter module is opened to allow inflow air to proceed along an input direction or an operation state in which multiple channel spaces are formed so that the inflow air passes through multiple preconfigured channel spaces while a contaminated material included in the inflow air is removed, and a spray module provided to spray an oil mist toward a surface of the first filter module.

Classes IPC  ?

• B01D 53/75 - Procédés multi-étapes
• B01D 53/78 - Procédés en phase liquide avec un contact gaz-liquide
• B01D 53/14 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par absorption
• B01D 46/00 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs
• B01D 46/56 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs avec plusieurs éléments filtrants, caractérisés par leur disposition relative
• B01D 53/30 - Commande par appareil d'analyse des gaz

Abrégé

A scan signal driver includes: a plurality of stages configured to be driven by dividing a first frame period into a display period and a sensing period, and to sequentially output scan signals at the display period, wherein each of the plurality of stages comprises: an output control circuit; and a memory control circuit, wherein the scan driver is configured to: irregularly set a specific stage of the plurality of stages at a display period every frame; control the specific stage to: store a voltage by using the memory control circuit; and output a sensing signal by using the stored voltage at a sensing period, and the memory control circuit includes: a second memory transistor configured to electrically connect an M node with an I node; and a third memory transistor configured to electrically connect the output control circuit with the I node.

Classes IPC  ?

• G09G 3/3266 - Détails des circuits de commande pour les électrodes de balayage
• G09G 3/3233 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED] organiques, p. ex. utilisant des diodes électroluminescentes organiques [OLED] utilisant une matrice active avec un circuit de pixel pour commander le courant à travers l'élément électroluminescent

Abrégé

The present invention relates to a composition for the prevention and treatment of ischemic cerebrovascular diseases, including cerebral infarction, the composition comprising gintonin as an active ingredient. Gintonin according to the present invention has the effect of reducing cerebral infarction volume and can increase survival rate after the onset of cerebral infarction, and thus can be effectively used for the prevention and treatment of cerebral infarction. In addition, the neuroprotective effect and damage prevention effect of gintonin pretreatment on human brain microvascular endothelial cells (HBMECs), which are human brain-derived vascular endothelial cells, and the neuroprotective effect and therapeutic effect of gintonin post-treatment were confirmed. As a result of mechanism verification, it was found that gintonin was effective in recovering the level of reduced nitric oxide (NO), which is known to be involved in the onset and pathophysiology of cerebral infarction. Therefore, the present invention can be used to improve the prevention and treatment of ischemic cerebrovascular diseases, including cerebral infarction, and thus, medical costs can be reduced.

Classes IPC  ?

• A61K 38/14 - Peptides contenant des radicaux saccharideLeurs dérivés
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale

Abrégé

The present invention relates to the use of α-2,6-sialylated immunoglobulin derived from human blood in preventing or treating dry eye syndrome or inflammatory eye diseases. Compared to IVIG, the α-2,6-sialylated immunoglobulin according to the present invention exhibits excellent therapeutic effects for dry eye syndrome even at a low dose without side effects such as fibrosis of corneal tissue, and also for intractable inflammatory eye diseases of varying severity.

Classes IPC  ?

• C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61P 27/02 - Agents ophtalmiques
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a liposome-based drug carrier for immune anticancer therapy, the carrier comprising: a liposome; an aptamer which is a target-specific ligand for cancer cells conjugated on the surface of the liposome; and an immunogenic chemo-anticancer agent and siRNA, an immunosuppressive protein inhibitor, which are co-loaded on the liposome. Accordingly, it is possible to induce a continuous tumor-specific anti-cancer immune response in cancer patients having a low response rate to a standalone immuno-oncologic agent therapy, and to reduce side effects due to non-specific drug delivery, thereby increasing the effects of immune anticancer therapy.

Classes IPC  ?

• A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
• A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
• A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
• A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 35/00 - Agents anticancéreux
• C12N 15/115 - Aptamères, c.-à-d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
• A61K 9/107 - Émulsions

Abrégé

RSRSRSS-DiHDPA can be effectively used in various industrial fields such as medicines, functional foods, and functional cosmetic products, and are expected to be involved in various physiological functions in animals including humans.

Classes IPC  ?

• C12P 7/6409 - Acides gras

Abrégé

A scan signal driver includes: stages to sequentially output scan signals in an active period, and to selectively output sensing signals in a vertical blank period. At least one of the stages includes: a sensing control circuit to supply a gate-on voltage to a sensing control node in response to a holding control signal during the active period, and to output the gate-on voltage of the sensing control node in response to a selectively input line select signal during the vertical blank period; an output node control circuit to supply the gate-on voltage to a pull-up node when the gate-on voltage of the sensing control node is output during the vertical blank period; and an output circuit to output a scan clock signal as a sensing signal to one of scan signal lines when the gate-on voltage is supplied to the pull-up node during the vertical blank period.

Classes IPC  ?

• G09G 3/3266 - Détails des circuits de commande pour les électrodes de balayage
• G09G 3/3233 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED] organiques, p. ex. utilisant des diodes électroluminescentes organiques [OLED] utilisant une matrice active avec un circuit de pixel pour commander le courant à travers l'élément électroluminescent

Abrégé

The present invention relates to: recombinant microorganisms expressing lipoxygenase; and recombinant microorganisms co-expressing lipoxygenase and Chlorella-derived decarboxylase. It was confirmed that when using lipoxygenase-based recombinant microorganisms according to the present invention as whole-cell biocatalysts, hydroxy fatty acids can be produced from unsaturated fatty acids. In addition, it was confirmed that when using the recombinant microorganisms co-expressing lipoxygenase and Chlorella-derived decarboxylase as whole-cell biocatalysts, secondary fatty alcohols can be produced from unsaturated fatty acids. Thus, the recombinant microorganisms constructed in the present invention can be used in various ways in the field of hydroxy fatty acid and secondary fatty alcohol production.

Classes IPC  ?

• C12P 7/6409 - Acides gras
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase

Abrégé

A method of generating a human model according to the present disclosure may include generating a plurality of feature maps from an input image, wherein the plurality of feature maps include a body center map, a part index map, a body part map and a parameter map, generating a part-attentive feature configured with feature maps for each body part based on the part index map and the body part map, readjusting the part-attentive feature based on the parameter map and generating a pose parameter based on the readjusted part-attentive feature.

Classes IPC  ?

• G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
• G06T 7/50 - Récupération de la profondeur ou de la forme
• G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
• G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
• G06V 40/10 - Corps d’êtres humains ou d’animaux, p. ex. occupants de véhicules automobiles ou piétonsParties du corps, p. ex. mains

Abrégé

A LiDAR and camera data fusion method includes generating a voxel-wise feature map based on point cloud data of a LiDAR sensor, generating a pixel-wise feature map based on image data of a camera, converting three-dimensional (3D) coordinates of point data of the voxel-wise feature map to two-dimensional (2D) coordinates, based on at least one predefined calibration parameter, and generating fused data by combining pixel data of the pixel-wise feature map and point data of the 2D coordinates.

Classes IPC  ?

• G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
• G06V 10/40 - Extraction de caractéristiques d’images ou de vidéos
• G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
• G06V 20/58 - Reconnaissance d’objets en mouvement ou d’obstacles, p. ex. véhicules ou piétonsReconnaissance des objets de la circulation, p. ex. signalisation routière, feux de signalisation ou routes

Abrégé

The present invention relates to a DNA aptamer for the diagnosis of colorectal cancer and, specifically, to a composition and a kit for the diagnosis of colorectal cancer, and a colorectal cancer-specific drug delivery composition, each comprising the aptamer consisting of the nucleotide sequences of SEQ ID NOS: 4 to 35. Exhibiting high affinity and specificity for colorectal cancer cell-derived small extracellular vesicles (sEV), the aptamer of the present invention can be used for the specific and accurate diagnosis of colorectal cancer. With the strong binding with specific protein biomarkers present on the sEV membrane, the DNA aptamer suppresses the metastatic potential of cancer through sEV and is expected to find applications in the treatment of colorectal cancer.

Classes IPC  ?

• C12N 15/115 - Aptamères, c.-à-d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
• C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
• C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
• A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention relates to a water electrolysis catalyst and a preparation method therefor. The water electrolysis catalyst according to the present invention has excellent oxygen evolution reaction (OER) activity and exhibits, even if an OER is carried out for a long time at a high current, excellent durability and stability, and thus can be used as an OER catalyst using fresh water and, in the future, using seawater.

Classes IPC  ?

• B01J 31/16 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination
• B01J 37/10 - Traitement thermique en présence d'eau, p. ex. de vapeur d'eau
• B01J 37/02 - Imprégnation, revêtement ou précipitation
• C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
• B01J 37/30 - Échange d'ions
• C25B 11/085 - Composé organique

Abrégé

The present invention relates to a biomarker for early diagnosis of kidney diseases, and use thereof. A composition, a kit and a method, according to one embodiment, enable kidney diseases or the risk of kidney diseases to be diagnosed at an early stage with higher accuracy, sensitivity and specificity. Particularly, the present invention enables classification into a normal group, a risk group (a stage having inherent risk factors), chronic kidney disease stage 1 (IRIS stage 1) or chronic kidney disease stages 2 to 4 (IRIS stages 2 to 4) with a sensitivity of 90% or higher and a specificity of 95% or higher on the basis of guidelines for staging chronic kidney disease (CKD) of the International Renal Interest Society (IRIS).

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

An object-based image encoding/decoding method and device of the present disclosure may include an image partition step which partitions an image to obtain a first object region, a region scaling step which scales the first object region based on a scaling factor of the first object region to obtain a second objection region, a region merging step which merges the second object region with at least one of an object region different from the second object region or a non-object region to obtain a merged image, and an image reconstruction step which reconstructs the merged image.

Classes IPC  ?

• H04N 19/119 - Aspects de subdivision adaptative, p. ex. subdivision d’une image en blocs de codage rectangulaires ou non
• H04N 19/124 - Quantification
• H04N 19/172 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c.-à-d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant une zone de l'image, p. ex. un objet la zone étant une image, une trame ou un champ
• H04N 19/184 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c.-à-d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant des bits, p. ex. de flux vidéo compressé

Abrégé

An image encoding/decoding method, device and recording medium based sed on multiple compression levels disclosure may include extracting a region of interest for machine vision from an input image, determining a compression level of the region of interest, and encoding the compression level of the region of interest.

Classes IPC  ?

• G06T 9/00 - Codage d'image
• G06V 10/25 - Détermination d’une région d’intérêt [ROI] ou d’un volume d’intérêt [VOI]

Abrégé

The present invention relates to a urea oxidation reaction (UOR) catalyst and a preparation method therefor, the catalyst comprising: a nickel-copper metal-organic framework; and a nickel hydroxide deposited on the nickel-copper metal-organic framework through electrodeposition. Therefore, the present invention can exhibit excellent catalyst activity in a urea oxidation reaction while being thin and having a high surface area.

Classes IPC  ?

• B01J 31/16 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination
• B01J 23/755 - Nickel
• B01J 37/34 - Irradiation ou application d'énergie électrique, magnétique ou ondulatoire, p. ex. d'ondes ultrasonores
• B01J 37/04 - Mélange
• B01J 37/08 - Traitement thermique
• C25B 3/09 - Composés contenant au moins un atome d’azote
• C25B 3/23 - Oxydation

Abrégé

Proposed are a method of preparing a metal nanostructure, which includes (a) preparing a first metal template whose surface is coated with a polymeric micelle containing an amphiphilic polymer and (b) causing the first metal template to react with a second metal ion through a galvanic replacement reaction, and a metal nanostructure prepared thereby. The amphiphilic polymer is used as a capping agent during the replacement reaction so that the micellar polymer is adsorbed onto the template, thereby selectively allowing the replacement reaction. Thus, unlike in existing technologies in which nanostructures having limited forms are prepared, nanostructures having a new two-dimensional structure, including nanostructures having a plurality of pores formed between nanoparticles, can be prepared. Additionally, a mixing ratio of two types of solvents that differ in polarity index is adjustable to control the size of the polymeric micelle, thereby changing the structural characteristics of a finally prepared metal nanostructure.

Classes IPC  ?

• B22F 1/145 - Traitement chimique, p. ex. passivation ou décarburation
• B22F 1/054 - Particules de taille nanométrique
• B22F 1/102 - Poudres métalliques revêtues de matériaux organiques
• C25B 11/061 - Métal ou alliage

Abrégé

The present invention relates to an organic semiconductor compound with high transmittance in the visible light spectrum and a use thereof.

Classes IPC  ?

• C07D 333/28 - Atomes d'halogènes
• C07D 277/32 - Composés hétérocycliques contenant des cycles thiazole-1, 3 ou thiazole-1, 3 hydrogénés non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des hétéro-atomes ou avec des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux atomes de carbone du cycle
• C07D 307/56 - Composés hétérocycliques contenant des cycles à cinq chaînons comportant un atome d'oxygène comme unique hétéro-atome du cycle non condensés avec d'autres cycles comportant deux ou trois liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des hétéro-atomes ou avec des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile, liés directement aux atomes de carbone du cycle
• C07D 345/00 - Composés hétérocycliques contenant des cycles comportant des atomes de sélénium ou de tellure comme uniques hétéro-atomes du cycle
• H10K 85/60 - Composés organiques à faible poids moléculaire
• H10K 30/20 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant des jonctions organiques-organiques, p. ex. des jonctions donneur-accepteur

Abrégé

A road surface recognition method may include extracting first point cloud data in a front road surface region of a vehicle from point cloud data generated by LiDAR of the vehicle, generating a point cloud map by use of a local map and the first point cloud data, determining a predicted driving route of the vehicle based on motion-related data of the vehicle; and generating a road surface height profile of the predicted driving route based on the point cloud map and the predicted driving route.

Classes IPC  ?

• B60W 40/06 - Calcul ou estimation des paramètres de fonctionnement pour les systèmes d'aide à la conduite de véhicules routiers qui ne sont pas liés à la commande d'un sous-ensemble particulier liés aux conditions ambiantes liés à l'état de la route
• B60W 40/105 - Vitesse
• B60W 40/11 - Mouvement de tangage
• B60W 40/114 - Mouvement de lacet
• G01S 17/89 - Systèmes lidar, spécialement adaptés pour des applications spécifiques pour la cartographie ou l'imagerie
• G06F 17/17 - Évaluation de fonctions par des procédés d'approximation, p. ex. par interpolation ou extrapolation, par lissage ou par le procédé des moindres carrés

Abrégé

A gate driving circuit includes a capacitor connected between a first gate of a pull-down transistor and a control node, and a control transistor connected between the control node and a ground terminal and having a gate connected to the ground terminal.

Classes IPC  ?

• G09G 3/3266 - Détails des circuits de commande pour les électrodes de balayage

Abrégé

The present invention relates to a biomarker for diagnosing immune-related diseases, a composition and kit for detecting the biomarker for diagnosing immune-related diseases, and a method for diagnosing immune-related diseases using same. According to the composition, kit, and method for diagnosing immune-related diseases in an aspect, it is possible to easily diagnose the level of immune-related diseases in a subject, whereby the subject's health can be monitored and immune-related diseases can be prevented and diagnosed.

Classes IPC  ?

• G01N 33/483 - Analyse physique de matériau biologique
• G01N 30/72 - Spectromètres de masse

Abrégé

The present disclosure relates to a method for mass production of extracellular vesicles by using a noxa protein-derived peptide and mesenchymal stem cells and, more specifically, to a method for mass production of extracellular vesicles having wound healing and immunomodulatory effects, wherein mesenchymal stem cells are cultured in a medium composition containing a noxa protein-derived peptide, glucose, sucrose, and 3-(N-morpholino)propanesulfonic acid [MOPS], whereby the extracellular vesicles can be obtained at high yield with high purity.

Classes IPC  ?

• C12N 5/073 - Cellules ou tissus embryonnairesCellules fœtales ou tissus fœtaux
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The present disclosure relates to a system for measuring changes in the vital signs of poultry and a method for predicting whether poultry is infected with pathogens using the same. The present disclosure can be helpfully used to determine an overall health condition including the outbreak of various poultry diseases by measuring quantitative changes in vital signs of poultry in real time. In particular, the present disclosure provides reliable real-time information about changes in vital signs through comparison of body temperature and noise measurement values of poultry for each time period reflecting circadian changes of the poultry, rather than simple comparison of the body temperature and noise measurement values with simple reference values, and thus can be used for early diagnosis of highly infectious pathogens such as avian influenza virus and early isolation of confirmed cases, and ultimately for effective prevention of the spread of diseases.

Classes IPC  ?

• A01K 45/00 - Autres appareils ou dispositifs pour l'aviculture, p. ex. dispositifs pour déterminer si un oiseau est prêt à pondre
• A01K 29/00 - Autres appareils pour l'élevage
• G16H 50/80 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la détection, le suivi ou la modélisation d’épidémies ou des pandémies, p. ex. de la grippe
• G01J 5/00 - Pyrométrie des radiations, p. ex. thermométrie infrarouge ou optique

Abrégé

An apparatus and method for estimating a vehicle pitch relative to a road. The apparatus includes a wheel speed sensor part which obtains wheel speed data, an inertial measurement unit (IMU) sensor part which obtains IMU data, a preprocessing part which extracts a stop section and a moving section on the basis of the wheel speed data and the IMU data, and a slope estimation part which estimates a vehicle pitch in the stop section and a road slope in the moving section and estimates a vehicle pitch relative to a road on the basis of the vehicle pitch and the road slope.

Classes IPC  ?

• G01C 9/00 - Mesure de l'inclinaison, p. ex. par clinomètres, par niveaux

Abrégé

Provided are polynucleotides encoding variants of nitrous oxide reductase proteins, recombinant microorganisms including a foreign gene encoding a variant of a nitrous oxide reductase protein, and a composition comprising the recombinant microorganism or the variant of a nitrous oxide reductase protein for use in removing nitrous oxide in a sample.

Classes IPC  ?

• C12N 9/06 - Oxydoréductases (1.), p. ex. luciférase agissant sur des composés contenant de l'azote comme donneurs (1.4, 1.5, 1.7)
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

Proposed is a recyclable epoxy compound containing an α,β-unsaturated ketone group and/or a hydroxy ketone group bonded through an aldol reaction between a ketone group and an aldehyde group containing a hydroxyl group among non-toxic natural materials, without using a bisphenol A type epoxy, a toxic material. In addition, proposed are a method of preparing the same compound, an epoxy composite material containing the same compound, and a method of degrading the same composite material.

Classes IPC  ?

• C08G 59/24 - Composés diépoxydés carbocycliques
• F03D 1/06 - Rotors
• C08G 59/68 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les catalyseurs utilisés
• C08G 59/50 - Amines
• C08G 59/06 - Polycondensats contenant plusieurs groupes époxyde par molécule de composés polyhydroxylés avec l'épihalohydrine ou ses précurseurs de polyphénols

Abrégé

The present invention relates to a pharmaceutical composition including an IL-32θ mutant for the prevention or treatment of inflammatory diseases and/or cancer and a use thereof. The Interleukin-32 theta mutant (IL-32θ mutant) of the present invention can inhibit inflammatory cytokines and chemokines, inflammatory mediators, and the metastasis and proliferation of cancer through intracellular pathways and can suppress the expression of Intracellular Adhesion Molecule-1 (ICAM-1) and Vascular Cell Adhesion Molecule-1 (VCAM-1) in Human Umbilical Vein Endothelial Cells (HUVECs), and thus can be used for preventing and treating inflammatory diseases such as atherosclerosis through the inhibition of monocyte-endothelial cell adhesion. The mutant can also be utilized as a research material for various cancers and/or inflammatory diseases.

Classes IPC  ?

• A61K 38/20 - Interleukines
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 35/00 - Agents anticancéreux
• C07K 14/54 - Interleukines [IL]

Abrégé

The present disclosure relates to a method for producing mesenchymal stem cells from pluripotent stem cells and mesenchymal stem cells prepared by the method. The present disclosure enables mesenchymal stem cells having superior proliferation rate while having superior intrinsic biological activity to be obtained with high yield by sequentially performing three-dimensional suspension culture using pluripotent stem cells, particularly induced pluripotent stem cells (iPSCs), as starting cells and adherent culture of cell aggregates formed therethrough. The mesenchymal stem cells produced by the method of the present disclosure can be usefully used in compositions for treating bone diseases, cartilage diseases or inflammatory and autoimmune diseases owing to high differentiation efficiency into bone and cartilage and superior anti-inflammatory activity.

Classes IPC  ?

• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The present invention relates to: a synthetic promoter operably linked to a daptomycin biosynthetic gene cluster; a gene construct for producing daptomycin in which the synthetic promoter and a daptomycin biosynthetic gene cluster are operably linked; a recombinant expression vector for producing daptomycin containing the genetic construct; and a transformant for producing daptomycin that has been transformed with the recombinant expression vector, wherein the synthetic promoter can increase the transcriptional activity of the daptomycin biosynthetic gene cluster, and the transformant that has been transformed with the recombinant expression vector containing the synthetic promoter and the daptomycin biosynthetic gene cluster can be effectively used in the field of medicine and pharmacy by enabling mass production of daptomycin.

Classes IPC  ?

• C12N 15/76 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour ActinomycesVecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Streptomyces
• C12N 15/52 - Gènes codant pour des enzymes ou des proenzymes
• C12P 21/00 - Préparation de peptides ou de protéines

Abrégé

MycobacteriumStreptomycesStreptomyces sp. bacteria, and a use thereof. It was found that soil mixed with the microorganisms according to the present invention has increased levels of organic acids (including lactic acid, pyruvic acid, and serotonin) and decreased levels of fatty acids and lipids (including palmitic acid and linoleic acid). In addition, alpha waves of the laryngeal cortex increased and heart rate decreased, and thus a stabilizing effect on the autonomic nervous system was exhibited. That is, soil mixed with the microorganisms according to the present invention can provide healing activity such as an improvement in psychological health.

Classes IPC  ?

• A61K 35/74 - Bactéries
• A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 37/00 - Médicaments pour le traitement des troubles immunologiques ou allergiques
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• C05F 11/08 - Engrais organiques comportant l'addition de cultures bactériennes, de mycélium ou similaires

Abrégé

The present invention relates to: a recyclable epoxy compound; a method for preparing same; an epoxy composite material comprising same; and a decomposition method thereof, wherein the epoxy compound does not use bisphenol A-type epoxy which is a toxic material but comprises an α,β-unsaturated ketone group and/or a hydroxy ketone group obtained by combining, from among non-toxic natural raw materials, a hydroxyl-group-containing aldehyde group and a ketone group through an aldol reaction.

Classes IPC  ?

• C07D 301/12 - Synthèse du cycle de l'oxirane par oxydation de composés non saturés, ou de mélanges de composés non saturés et de composés saturés par le peroxyde d'hydrogène ou par des peroxydes ou peracides inorganiques
• C08G 59/22 - Composés diépoxydés
• C08G 59/50 - Amines
• C08G 59/44 - Amides
• C08G 59/40 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les agents de durcissement utilisés
• C08G 59/68 - Macromolécules obtenues par polymérisation à partir de composés contenant plusieurs groupes époxyde par molécule en utilisant des agents de durcissement ou des catalyseurs qui réagissent avec les groupes époxyde caractérisées par les catalyseurs utilisés

Abrégé

The present disclosure relates to a method for producing extracellular vesicles from three-dimensionally cultured stem cells. The method of the present disclosure can produce stem cell-derived extracellular vesicles with a high yield through orbital shaking culture of stem cell aggregates in the presence of TGF-β and thus can be usefully used in an industrial-scale mass production process of exosomes that can be utilized as a pharmaceutical ingredient substituting for a cell therapeutic agent. Furthermore, the exosomes obtained by the method of the present disclosure have significantly improved immunoregulatory functions as compared to the exosomes produced by the existing method and, therefore, can be applied as a superior therapeutic composition for various inflammations or autoimmune diseases.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux

Abrégé

In the present invention, among blood metabolites, amino acids, organic compounds and oxylipins that were statistically significantly differentiated from the control group, were selected from type 2 diabetes patients. Specifically, asparagine, aspartic acid, glutamic acid, cysteine, lysine, citric acid, and uric acid, and 12-oxo ETE, 15-oxo ETE, 9-oxo ODE, and 20-carboxy leukotriene B4, which are oxylipins, were confirmed to have cutoff values of AUC>0.7. In addition, the blood metabolites showed a significant difference between a DME patient group and a non-DME patient group, and thus were confirmed to be usable for accurate diagnosis of DME.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• G01N 30/72 - Spectromètres de masse
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The present invention relates to an influenza virus surface protein-derived recombinant hemagglutinin (HA) protein forming a trimer and use thereof, and more specifically to a recombinant vector for producing an influenza virus surface protein-derived HA protein forming a trimer, a transformant transformed by the recombinant vector, a method for producing an influenza virus surface protein-derived HA protein forming a trimer using the recombinant vector, an influenza virus surface protein-derived HA protein produced by the method, and the use thereof in preventing, ameliorating or treating influenza virus-infected disease.

Classes IPC  ?

• A61K 39/145 - Orthomyxoviridae, p. ex. virus de l'influenza
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus

Abrégé

The present invention relates to: a 3-fluoropyridine-based organic semiconductor compound for an electron donor, based on low cost and high processability and having a wide bandgap; an organic electronic device comprising same; and an organic solar cell comprising a photoactive layer including same as an electron donor. The 3-fluoropyridine-based organic semiconductor compound according to the present invention can be used as a photoactive layer material of a bulk heterojunction or layer-by-layer structure in combination with conventional donors or acceptors, and therefore, an organic solar cell with high performance/high transmittance can be provided.

Classes IPC  ?

• C07D 409/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
• C07D 495/04 - Systèmes condensés en ortho
• C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
• H10K 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
• H10K 30/00 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire

Abrégé

The present invention relates to a method for electrospinning of a high-efficiency nanofiber air filter by using a PVDF-G-POEM double comb copolymer. According to the present invention, provided is a nanofiber air filter which: can adsorb both hydrophobic dust and hydrophilic dust; exhibits a uniform diameter distribution of nanofibers, thus compensating for the disadvantages of the prior art of the large diameter and non-uniform distribution of a filter; can exhibit excellent separation efficiency through the manufacture of nanofibers with a diameter similar to the mean free path of oxygen molecules; and has a slip effect due to a narrow fiber diameter, thus having high filter efficiency.

Classes IPC  ?

• B01D 39/16 - Autres substances filtrantes autoportantes en substance organique, p. ex. fibres synthétiques
• D01D 5/00 - Formation des filaments, fils ou similaires

Abrégé

A nonameric peptide represented by the amino acid sequence of SEQ ID NO: 1 or an enantiomer thereof according to the present invention is low in cytotoxicity and superb in terms of proteolysis stability, antibacterial activity, and anti-inflammatory activity and has a remarkable therapeutic effect on Gram-negative bacterial infectious diseases, sepsis, or septic shock. Accordingly, the peptide can be advantageously applied to an antibacterial composition, an anti-inflammatory composition, and a pharmaceutical composition for prevention or treatment of Gram-negative bacterial infectious diseases, sepsis, or septic shock.

Classes IPC  ?

• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A01N 37/46 - Dérivés N-acylés
• A61K 38/00 - Préparations médicinales contenant des peptides
• A61P 31/04 - Agents antibactériens

Abrégé

The present invention relates to a recombinant Newcastle virus vector comprising a hemagglutinin gene of low pathogenic avian influenza, and a vaccine composition using same. The present invention includes the HA gene of A/Korean native chicken/Korea/N20-132/2020 (H9N2) LPAIV in the existing Newcastle virus vector, thereby being capable of obtaining excellent preventive effects against the Newcastle disease virus and low pathogenic avian influenza.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus
• A61K 39/145 - Orthomyxoviridae, p. ex. virus de l'influenza
• A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus

Abrégé

The present invention relates to a probe set for an isothermal single reaction using a split T7 promoter and a use thereof. In the present invention, a design is made to introduce a split T7 promoter into a 3-way junction structure to produce a large quantity of fluorescent RNA aptamers at an isothermal temperature in the presence of a target molecule, and a nucleic acid biomarker can be detected rapidly and conveniently with only one enzyme in one pot. The probe set allows for various applications through high-sensitivity detection of multiple nucleic acid biomarkers and detection in which analysis is performed without an additional nucleic acid extraction process. In one pot, multiplex analysis can be conducted and molecular diagnosis can be made of various entities including viruses and pathogens.

Classes IPC  ?

• C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
• C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
• C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries

Abrégé

An embodiment of the present disclosure provides an extracellular matrix-based bioadhesive as an adhesive in the form of a composition including an extracellular matrix-containing hydrogel and a gelatin curing agent, wherein the extracellular matrix-containing hydrogel is gelatinized. Since the extracellular matrix-based bioadhesive according to an embodiment of the present disclosure has the same or similar rheological properties as gelatin, the bioadhesive has flowability at a temperature of 30° C. or higher and may be evenly and easily applied to a lesion site in the body. In addition, the extracellular matrix-based bioadhesive according to an embodiment of the present disclosure may adhere well to the lesion site because of a level of adhesive strength that is about 2 to 6 times higher than that of fibrin glue used as a commercial tissue adhesive. In addition, the extracellular matrix-based bioadhesive according to an embodiment of the present disclosure is based on a tissue-derived extracellular matrix, and thus includes a tissue-derived wound healing component or a tissue regeneration component, and may be used for wound healing or tissue regeneration in addition to bioadhesive applications.

Classes IPC  ?

• A61L 24/00 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie
• A61L 24/10 - PolypeptidesProtéines

Abrégé

The present invention relates to a pharmaceutical composition, a food composition, a cosmetic composition, and a feed composition, each comprising an extract from oat sprouts and/or stems for alleviating hair loss or promoting hair growth, a pharmaceutical composition comprising an oat sprout and/or extract for preventing or treating hair loss, and a medical device. The oat sprout and/or extract of the present invention has an excellent effect of alleviating hair loss and promoting hair growth by encouraging the proliferation of HDP cells and the expression of related genes, and thus can be used in drugs, medical devices, feeds, foods, health functional foods, cosmetics, and so on which are useful for preventing and treating hair loss.

Classes IPC  ?

• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A23L 29/281 - Protéines, p. ex. gélatine ou collagène
• A23L 33/125 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sirops d'hydrate de carboneModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des sucresModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des alcools de sucreModification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs contenant des hydrolysats d'amidon
• A23P 10/20 - AgglomérationGranulationMise en comprimés
• A23P 10/28 - Mise en comprimésFabrication de produits alimentaires en barres par compression d’un mélange pulvérulent sec
• A23P 10/30 - Mise en capsules de particules, p. ex. additifs alimentaires
• A61K 36/899 - Poaceae ou Gramineae (famille des céréales), p. ex. bambou, blé ou canne à sucre
• A61P 19/00 - Médicaments pour le traitement des troubles du squelette
• A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
• A23K 50/00 - Produits alimentaires spécialement conçus pour des animaux spécifiques

Abrégé

The present invention relates to a fire-extinguishing microcapsule, a method for manufacturing same, and a fire-extinguishing composition comprising same, wherein the microcapsule comprises: a core containing a non-inflammable material; a first shell layer covering the core and containing inorganic nanoparticles and a water-soluble polymer; and a second shell layer covering the first shell layer and containing a polymer.

Classes IPC  ?

• A62D 1/00 - Compositions pour éteindre les incendiesEmploi de produits chimiques pour éteindre les incendies
• B01J 13/14 - Polymérisation, réticulation

Abrégé

There are provided a flame retardant element for suppressing flame propagation when a fire occurs during the use of a lithium secondary battery, thereby ensuring safety of the secondary battery while in use, a method for manufacturing the flame retardant element, and a secondary battery module and a secondary battery pack comprising the flame retardant element. The proposed flame retardant element is a composite pad having a stack of at least two polymer resin single layers including fire extinguishing materials having different fire extinguishing and flame retardant mechanisms, the composite pad includes a first polymer resin single layer and a second polymer resin single layer, and the first polymer resin single layer includes the fire extinguishing material which takes effect in a lower temperature range than the second polymer resin single layer.

Classes IPC  ?

• C08K 3/22 - OxydesHydroxydes de métaux
• C08K 3/16 - Composés contenant des halogènes
• H01M 50/143 - Boîtiers primairesFourreaux ou enveloppes pour protéger contre les dommages causés par des facteurs externes ignifugesBoîtiers primairesFourreaux ou enveloppes pour protéger contre les dommages causés par des facteurs externes à l'épreuve des explosions

Abrégé

An analog-to-digital converter (ADC) for converting an analog signal into a digital signal includes an amplifier circuit configured to receive the analog signal, and to generate a plurality of amplifier signals by amplifying the analog signal; a comparison circuit configured to compare a plurality of voltage levels corresponding to the plurality of amplifier signals with a positive reference voltage level and a negative reference voltage level, and to output conversion target signals based on a result of the comparison; and a converter circuit configured to convert the conversion target signals into a plurality of digital signals.

Classes IPC  ?

• H03M 1/12 - Convertisseurs analogiques/numériques
• H03M 1/36 - Valeur analogique comparée à des valeurs de référence uniquement simultanément, c.-à-d. du type parallèle

Abrégé

The present invention relates to a metal nanostructure preparation method and a metal nanostructure prepared thereby, the method comprising the steps of: (a) preparing a first metal template surface-coated with a polymeric micelle comprising an amphiphilic polymer; and (b) performing a galvanic replacement reaction between the first metal template and a second metal ion. According to the present invention, an amphiphilic polymer is used as a capping agent during galvanic replacement reaction so as to adsorb a micellar polymer on a metal template, thereby allowing a galvanic replacement reaction to be selectively performed, and thus, unlike a nanostructure with a delimited shape, such as hollow nanoparticles, prepared through a conventional technique, a nanostructure having a new two-dimensional structure including a nanostructure having a lot of pores formed between nanoparticles can be prepared, and since the mixing ratio of two types of solvents having different polarity indices is adjusted to control the size of the polymeric micelle adsorbed on the template, the structural characteristics of a finally prepared metal nanostructure can be changed.

Classes IPC  ?

• B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
• B82B 1/00 - Nanostructures formées par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
• C22C 1/08 - Alliages poreux avec pores ouverts ou fermés
• C22C 1/10 - Alliages contenant des composants non métalliques
• B82Y 40/00 - Fabrication ou traitement des nanostructures

Abrégé

The present invention relates to mesenchymal stem cells, extracellular vesicles isolated therefrom, and a use thereof. The mesenchymal stem cells of the present invention exhibit upregulated expression levels of at least one marker selected from among SPP1, PLAU, ITGA6, CENPI, and BUB1 and/or a downregulated expression level of the marker PTGS2, thereby remarkably decreasing levels of inflammatory cytokines such as TNF-α, IL-6, etc., and are therefore effective for preventing, ameliorating, alleviating, or treating various inflammatory diseases. Specifically, when administered into interstitial cystitis/bladder pain syndrome (IC/BPS) animal models, the mesenchymal stem cells or stem cell-derived extracellular vesicles isolated therefrom of the present invention restore the inner bladder wall broken down in the IC/BPS induction process and palliate inflammation, thus exhibiting excellent therapeutic efficacy for interstitial cystitis/bladder pain syndrome. In addition, the mesenchymal stem cells or the stem cell-derived extracellular vesicles isolated therefrom of the present invention has excellent wound healing effects and thus can be advantageously used for wound healing.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• C12N 13/00 - Traitement de micro-organismes ou d'enzymes par énergie électrique ou ondulatoire, p. ex. par magnétisme, par des ondes sonores
• C12M 1/42 - Appareils pour le traitement de micro-organismes ou d'enzymes au moyen d'énergie électrique ou ondulatoire, p. ex. magnétisme, ondes sonores
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 13/10 - Médicaments pour le traitement des troubles du système urinaire de la vessie
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires

Abrégé

The present invention relates to stem cell-derived extracellular vesicles, and a use thereof. Stem cell-derived extracellular vesicles of the present invention allow one or more proteins selected from COL6A1, COL6A3, TNC, EIF4E, HSP90AB1, HSP90B1, RAC1, TGF-β1 and TGM2 to be highly expressed, so as to remarkably reduce the amounts of inflammatory cytokines such as TNF-α and IL-6, and thus are effective in the prevention, reduction, alleviation, or treatment of various inflammatory diseases. Particularly, when administered to an animal model of interstitial cystitis/bladder pain syndrome (IC/BPS), the stem cell-derived extracellular vesicles of the present invention allow the lining of the bladder, damaged during the induction of IC/BPS, to be restored, the degree of inflammation to be reduced, and bladder internal pressure to be restored, and exhibit a voiding cycle similar to that of a control group, and thus the extracellular vesicles have the excellent effect of treating interstitial cystitis/bladder pain syndrome. In addition, stem cell-derived extracellular vesicles of the present invention remarkably increase the migration of cells, and have an excellent wound healing effect, and thus can be effectively used for wound healing.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• A61P 13/10 - Médicaments pour le traitement des troubles du système urinaire de la vessie
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires

Abrégé

Disclosed are an apparatus and method for correcting a transition error of a pulse width-based current domain in-memory neural network calculator. The apparatus for correcting a transition error of a pulse width-based current domain in-memory neural network calculator according to one embodiment of the present invention may comprise: an input unit for applying input data and unit pulse data on the basis of a pulse width modulation method; a calculation unit which obtains a first calculation result by performing a calculation based on the input data and a weight of a neural network, and obtains a second calculation result by performing a calculation based on the unit pulse data; and a charge integration unit for sampling a charge corresponding to an output current obtained from the first calculation result and the second calculation result.

Classes IPC  ?

• G06N 3/063 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques
• G06N 3/04 - Architecture, p. ex. topologie d'interconnexion
• G06N 3/08 - Méthodes d'apprentissage

Abrégé

The present invention relates to a method for manufacturing a semi-transparent solar cell including a high transmittance charge transport layer, and more particularly, to a solar cell having high transmittance and excellent performance in a visible light region by using a composite transparent electrode composed of a charge transport layer and an electrode having high transmittance and high mobility and changing a composition thereof. The semi-transparent solar cell into which the composite transparent electrode is used according to the present invention increases the transmittance of the light which passed, after being incident on the solar cell, through a light receiving electrode and is utilized for power generation in a photoactive layer, thereby appearing semi-transparent in the visible light region and having excellent transmittance. In addition, the semi-transparent solar cell according to the present invention can improve the photoelectric conversion efficiency (PCE) based on the high mobility characteristics of the composite transparent electrode.

Classes IPC  ?

• H01L 51/44 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement - Détails des dispositifs
• H01L 51/42 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement en énergie électrique, soit comme dispositifs de commande de l'énergie électrique par ledit rayonnement
• H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives

Abrégé

A display apparatus is disclosed, which includes a pixel. The pixel includes first through fifth transistors and a light emitting element. The first transistor includes a control electrode electrically connected to a first node, an input electrode that receives a first power voltage and an output electrode electrically connected to the light emitting element. The second transistor includes a control electrode that receives a scan signal, an input electrode that receives a grayscale data voltage and an output electrode electrically connected to a second node. The third transistor includes a control electrode electrically connected to the second node, an input electrode that receives a reference voltage and an output electrode electrically connected to the first node. The fourth transistor includes a control electrode that receives the scan signal, an input electrode that receives a bias data voltage and an output electrode electrically connected to the first node. The fifth transistor includes a control electrode that receives a sensing control signal, an input electrode that receives an initialization voltage and an output electrode electrically connected to the light emitting element.

Classes IPC  ?

• G09G 3/3225 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED] organiques, p. ex. utilisant des diodes électroluminescentes organiques [OLED] utilisant une matrice active

Abrégé

The present invention relates to an anti-freezing disinfectant composition and a preparation method therefor. The anti-freezing disinfectant according to the present invention contains potassium hydroxide, potassium acetate, sodium chloride, and sodium sulfate and exhibits anti-bacterial and anti-viral activities within a short time even at a low temperature. Thus, it can be used to kill infectious bronchitis virus or poultry influenza virus.

Classes IPC  ?

• A01N 59/08 - Chlorures des métaux alcalinsChlorures des métaux alcalino-terreux
• A01N 59/02 - SoufreSéléniumTellureLeurs composés

Abrégé

The present disclosure relates to a composition containing extracellular vesicles isolated from skeletal muscle-derived stem cells as active ingredients, which exhibits the effect of skin aging delay, wound healing, scar reduction and skin whitening, thereby improving skin condition. The present disclosure can not only utilize tissues wasted after surgical operation, thus allowing easy supply of raw materials, but also takes advantage of natural substances, thereby being free from the risk of side effects even upon long-term administration. The composition of the present disclosure promotes the secretion of collagen, reduces reactive oxygen species and promotes re-epithelialization at wound site while remarkably inhibiting melanocyte proliferation, tyrosinase activity and melanogenesis. Accordingly, it can facilitate effective recovery from skin tissue damage caused by oxidative stress, physical wound, intrinsic aging at cell or tissue levels, or hyperpigmentation.

Classes IPC  ?

• A61K 35/34 - MusclesCellules musculaires lissesCœurCellules souches cardiaquesMyoblastesMyocytesCardiomyocytes
• A61K 8/98 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés d'origine animale
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

Disclosed are a method and apparatus for self-training of machine reading comprehension to improve domain adaptation. The method for self-training of the machine reading comprehension may include generating a pseudo training data set comprising pseudo-questions and pseudo-answers in response to a change in a domain to which a trained machine reading comprehension model is to be applied, refining the pseudo training data set, and retraining the machine reading comprehension model and a pseudo-question generator that generates the pseudo-questions using the refined pseudo training data set.

Classes IPC  ?

• G06N 20/00 - Apprentissage automatique
• G06F 40/289 - Analyse syntagmatique, p. ex. techniques d’états finis ou regroupement

Abrégé

A hair perm forming method using electrolyzed water multiple times or for a predetermined period of time or more was revealed to have effects that cause very little damage to the hair to enable repeated treatments, enable perming of damaged hair and blonde hair compared with existing methods, show oxidative power higher than that of hydrogen peroxide, cause less hair damage, suppress dandruff bacteria, and significantly decrease the elution of dyes after perming. Therefore, the hair perm forming method can be advantageously used to effectively form a perm without harm to the human body. In addition, the washing of dyed and permed hair, dyed hair, and bleached hair with electrolyzed water, compared with washing with distilled water, has advantages in that the tensile strength of hair is maintained and the dye loss from the dyed hair is less.

Classes IPC  ?

• A45D 7/04 - Procédés pour onduler, décrêper ou boucler les cheveux chimiques
• C02F 1/467 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse par désinfection électrochimique
• C02F 1/42 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par échange d'ions

Abrégé

Disclosed herein is a method for compressing an image for machine vision, the method including detecting objects in an input image using an object detection network, generating a foreground image including bounding boxes corresponding to the objects and a background image, which is an image acquired by excluding the bounding boxes from the input image, encoding the foreground image and the background image, and decoding the encoded foreground image and the encoded background image.

Classes IPC  ?

• G06T 7/194 - DécoupageDétection de bords impliquant une segmentation premier plan-arrière-plan
• G06V 10/20 - Prétraitement de l’image
• G06V 10/28 - Quantification de l’image, p. ex. seuillage par histogramme visant à discriminer entre les formes d’arrière-plan et d’avant-plan
• G06T 9/00 - Codage d'image

Abrégé

The present invention relates to: recombinant microorganisms expressing lipoxygenase; and recombinant microorganisms co-expressing lipoxygenase and chlorella-derived decarboxylase. It was confirmed that when using lipoxygenase-based recombinant microorganisms according to the present invention as whole-cell biocatalysts, hydroxy fatty acids can be produced from unsaturated fatty acids. In addition, it was confirmed that when using the recombinant microorganisms co-expressing lipoxygenase and chlorella-derived decarboxylase as whole-cell biocatalysts, secondary fatty alcohols can be produced from unsaturated fatty acids. Thus, the recombinant microorganisms constructed in the present invention can be used in various ways in the field of hydroxy fatty acid and secondary fatty alcohol production.

Classes IPC  ?

• C12N 1/20 - BactériesLeurs milieux de culture
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• C12P 7/6409 - Acides gras
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating muscular atrophy or cachexia, comprising an extract containing ginseng-derived gintonin, a fraction thereof, or gintonin, as an active ingredient.

Classes IPC  ?

• A61K 36/258 - Panax (ginseng)
• A61K 38/14 - Peptides contenant des radicaux saccharideLeurs dérivés
• A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés

Abrégé

A display apparatus includes a display panel, a driving controller and a data driver. The display panel displays an image based on input image data. The driving controller generates a data signal based on the input image data, determines an optical flow based on previous frame data of the input image data and present frame data of the input image data and determines a user's self-motion using the optical flow. The data driver converts the data signal to a data voltage and outputs the data voltage to the display panel.

Classes IPC  ?

• G06T 7/207 - Analyse du mouvement pour l’estimation de mouvement sur une hiérarchie des résolutions
• G02B 27/01 - Dispositifs d'affichage "tête haute"
• G06T 3/40 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement
• G06V 10/46 - Descripteurs pour la forme, descripteurs liés au contour ou aux points, p. ex. transformation de caractéristiques visuelles invariante à l’échelle [SIFT] ou sacs de mots [BoW]Caractéristiques régionales saillantes

Abrégé

The present invention relates to a composition for promoting the proliferation of stem cells, and a composition for preventing or treating ischemic diseases. The present invention makes it possible to identify key fragments of FGF2 protein that interact most effectively with FGFR1, and use the fragments to effectively induce diverse biological processes, including the in vitro proliferation of stem cells and the promotion of angiogenesis, involving the FGFR1-FGF2 signaling pathway. In addition, the present invention makes it possible to identify, in the FGF2 protein, a core part that substantially mutually binds with FGFR1, which is a receptor, and rapidly and reliably investigate basic therapeutic agent candidate materials for various diseases, such as cancer, caused by excessive angiogenesis, on the basis of whether or not the interaction between the FGF2 protein and FGFR1 is impeded.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• A61K 38/18 - Facteurs de croissanceRégulateurs de croissance
• A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p. ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénale
• A23L 33/18 - PeptidesHydrolysats de protéines
• G01N 33/74 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des hormones
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention relates to a method for mass production of extracellular vesicles by using a noxa protein-derived peptide and mesenchymal stem cells and, more specifically, to a method for mass production of extracellular vesicles having wound healing and immunomodulatory effects, wherein mesenchymal stem cells are cultured in a medium composition containing a noxa protein-derived peptide, glucose, sucrose, and 3-(N-morpholino)propanesulfonic acid [MOPS], whereby the extracellular vesicles can be obtained at high yield with high purity.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A23L 29/00 - Aliments ou produits alimentaires contenant des additifsLeur préparation ou leur traitement

Abrégé

The present invention relates to a virtual crop cultivation system using augmented reality and virtual reality. The virtual crop cultivation system using augmented reality and virtual reality comprises: a server which provides a mobile game application for virtual crop cultivation, and stores crop cultivation game data, crop cultivation result data, user data, and service data; and a user terminal which runs the mobile game application, receives the crop cultivation game data from the server, and receives a user input for the virtual crop cultivation so as to generate and output the crop cultivation result data on the basis of the received crop cultivation game data and user input. The server may provide virtual crop cultivation game data in either augmented reality or virtual reality in consideration of image information collected from an image sensor provided in an actual crop cultivation environment.

Classes IPC  ?

• A63F 13/825 - Éducation de personnages virtuels
• A63F 13/335 - Dispositions d’interconnexion entre des serveurs et des dispositifs de jeuDispositions d’interconnexion entre des dispositifs de jeuDispositions d’interconnexion entre des serveurs de jeu utilisant des connexions de réseau étendu [WAN] utilisant l’Internet
• G06Q 50/10 - Services
• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
• G06Q 50/22 - Aide sociale ou assistance sociale, p. ex. activités de développement communautaire ou services de consultation

Abrégé

A high precision position estimation method through a road shape classification-based map matching implemented by a high precision position estimation system of an autonomous vehicle includes classifying a road into a straight lane, a curved lane, and a clothoid curve lane by the lane matching between a sensor lane segment and a map lane segment, generating a movement amount value calculated by applying a geometric feature-based map matching or an optimization-based map matching to the classified lane as a covariance matrix, and calculating the latitude, longitude, and traveling direction of a vehicle to be estimated by combining the covariance matrix with sensor measurement values of a vehicle speed and a yaw rate by an extended Kalman filter.

Classes IPC  ?

• G01C 21/16 - NavigationInstruments de navigation non prévus dans les groupes en utilisant des mesures de la vitesse ou de l'accélération exécutées à bord de l'objet navigantNavigation à l'estime en intégrant l'accélération ou la vitesse, c.-à-d. navigation par inertie
• B60W 60/00 - Systèmes d’aide à la conduite spécialement adaptés aux véhicules routiers autonomes
• G01C 21/34 - Recherche d'itinéraireGuidage en matière d'itinéraire

Abrégé

The present invention relates to a plant cultivator. The plant cultivator can comprise: a housing unit having a cultivating space in which a plant can be cultivated, and comprising a plurality of image sensors provided on the upper surface to capture images of the cultivating space; a plant planting pot apparatus accommodated in the cultivating space and having a body part, which has a planting space in which a plant is planted, and a learning gardening control module part which is provided in one area of the body part; and a cultivator control unit providing a user terminal with at least one of images obtained by the plurality of image sensors.

Classes IPC  ?

• A01G 9/24 - Dispositifs de chauffage, d'aération, de régulation de la température ou d'irrigation dans les serres, les châssis ou les installations similaires
• A01G 9/02 - Récipients, p. ex. pots ou jardinières Verres pour la culture des fleurs
• A01G 9/26 - Dispositifs électriques
• G09B 19/00 - Enseignement non couvert par d'autres groupes principaux de la présente sous-classe
• G06Q 50/10 - Services
• A01G 27/00 - Dispositifs automatiques d'arrosage, p. ex. pour pots de fleurs
• A01G 13/08 - Appareils mécaniques pour la circulation d'air

Abrégé

The present invention relates to a composition comprising a defensin-derived decameric peptide as an active ingredient for prevention or treatment of sepsis and, more specifically, to a pharmaceutical composition comprising the defensin-derived decameric peptide Pro10-1 or Pro10-1D as an active ingredient for prevention or treatment of sepsis or septic shock. In the present invention, Pro10-1 or Pro10-1D was identified to have an antibacterial activity against Gram-negative bacteria. Particularly, with increased cationicity and decreased hydrophobicity given thereto, Pro10-1D, which has arginine (Arg) and D-amino acid conversion added at the N-terminus thereof, was identified to decrease in toxicity, have improved permeability to negatively charged bacterial membranes, and exhibit the effects of excellent antibacterial activity, resistance to proteinases, endotoxin neutralization/clearance, and biofilm formation inhibition. Furthermore, Pro10-1D was identified to exhibit a remarkable anti-inflammatory effect by inhibiting TLR4 downstream, alleviate inflammatory insult in sepsis mouse models, and have a protective effect against organ dysfunction in sepsis mice. Thus, Pro10-1 or Pro10-1D of the present invention can find advantageous applications as a novel peptide antibiotic for effective treatment of sepsis or septic shock.

Classes IPC  ?

• A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
• A61P 31/04 - Agents antibactériens
• A23L 33/18 - PeptidesHydrolysats de protéines

Abrégé

The present invention relates to a system for measuring changes in vital signs of poultry and a method for predicting whether poultry is infected with pathogens by using same. The present invention can be helpfully used to determine an overall health condition including the outbreak of various poultry diseases by measuring quantitative values of changes in biological vitality of poultry in real time. In particular, the present invention provides reliable real-time information about changes in biological vitality through a comparison of body temperature and noise measurement values of poultry for each time period reflecting circadian changes of the poultry, rather than a simple comparison of the body temperature and noise measurement values with simple reference values, and thus can be used for early diagnosis of highly infectious pathogens such as avian influenza virus and early isolation of confirmed cases, and ultimately the effective prevention of the spread of diseases.

Classes IPC  ?

• G06Q 50/02 - AgriculturePêcheForesterieExploitation minière
• A61B 5/01 - Mesure de la température de parties du corps
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A01K 29/00 - Autres appareils pour l'élevage
• A01K 31/00 - Volières, poulaillers ou logements des oiseaux
• A01K 31/22 - Volières
• G08B 21/18 - Alarmes de situation
• G16H 50/80 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la détection, le suivi ou la modélisation d’épidémies ou des pandémies, p. ex. de la grippe

Abrégé

The present application relates to a method for screening customized postbiotics, the method comprising the steps of: culturing lactic acid bacteria; extracting a plurality of metabolites from the cultured lactic acid bacteria; analyzing the plurality of extracted metabolites by using multiple mass spectrometry; converting the results of the analysis using multiple mass spectrometry into statistical values; applying multivariate statistical analysis to the values, and thereby grouping the plurality of metabolites; and analyzing the phenotypes of the grouped metabolites.

Classes IPC  ?

• C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
• A61K 35/74 - Bactéries
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes

Abrégé

The present invention provides an antibacterial or antiviral composition comprising hydroxyapatite and calcium hydroxide, and a manufacturing method therefor. When advantage is taken thereof, an antibacterial or antiviral composition comprising hydroxyapatite and calcium hydroxide and a manufacturing method therefor according to the present invention allow the isolation and mass production of a composition containing hydroxyapatite and calcium hydroxide from shells. If prepared, a product comprising hydroxyapatite and calcium hydroxide exhibits excellent antibacterial and antiviral effects.

Classes IPC  ?

• A01N 59/26 - PhosphoreSes composés
• C01B 25/32 - Phosphates de magnésium, de calcium, de strontium ou de baryum
• C09D 5/14 - Peintures contenant des biocides, p. ex. fongicides, insecticides ou pesticides
• C09D 7/61 - Adjuvants non macromoléculaires inorganiques
• C08J 7/04 - Revêtement
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08K 3/22 - OxydesHydroxydes de métaux
• A61K 8/19 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés inorganiques
• A61Q 17/00 - Préparations protectricesPréparations employées en contact direct avec la peau pour protéger des influences extérieures, p. ex. des rayons du soleil, des rayons X ou d'autres rayons nuisibles, des matériaux corrosifs, des bactéries ou des piqûres d'insectes

Abrégé

Disclosed are an analog-to-digital converter (ADC), an electronic device including the ADC, and an operating method of the ADC. The ADC includes a first stage that includes a plurality of channels, generates a first sampling signal by sequentially sampling a first analog signal based on time interleaving, and generates a first digital signal and a first residual signal corresponding to the first analog signal by performing analog-to-digital conversion based on the first sampling signal, an amplifier that amplifies the first residual signal, and a second stage that includes a plurality of channels, generates a second sampling signal by sequentially sampling the amplified first residual signal based on time interleaving, and generates a second digital signal and a second residual signal corresponding to the first analog signal by performing analog-to-digital conversion based on the second sampling signal. The number of the plurality of channels included in the first stage is odd-numbered.

Classes IPC  ?

• H03M 1/12 - Convertisseurs analogiques/numériques
• H03M 1/46 - Valeur analogique comparée à des valeurs de référence uniquement séquentiellement, p. ex. du type à approximations successives avec convertisseur numérique/analogique pour fournir des valeurs de référence au convertisseur

Abrégé

A display device includes a scan write line for receiving a scan write signal, a first driving voltage line for receiving a first driving voltage, a first data line for receiving first data voltages, a second data line for receiving second data voltages, and a sub-pixel connected to the scan write line, the first data line, the second data line, and the first driving voltage line, wherein the sub-pixel includes a light emitting element connected to the first driving voltage line, a constant current generator configured to apply a driving current to the light emitting element according to a first data voltage among the first data voltages of the first data line, and a light emission period controller configured to control a light emission period of the light emitting element according to a second data voltage among the second data voltages of the second data line.

Classes IPC  ?

• G09G 3/3266 - Détails des circuits de commande pour les électrodes de balayage
• G09G 3/3291 - Détails des circuits de commande pour les électrodes de données dans lequel le circuit de commande de données fournit une tension de données variable pour le réglage du courant à travers les éléments électroluminescents, ou de la tension aux bornes de ces éléments

Abrégé

A barristor junction array device and a manufacturing method therefor are disclosed. A barristor junction array device according to one embodiment comprises: a substrate; a two-dimensional semiconductor formed on the substrate in a first direction; and graphene formed on the two-dimensional semiconductor in a second direction, wherein a barristor device is formed at each position at which the two-dimensional semiconductor and the graphene are bonded.

Classes IPC  ?

• H01C 7/10 - Résistances fixes constituées par une ou plusieurs couches ou revêtementsRésistances fixes constituées de matériaux conducteurs en poudre ou de matériaux semi-conducteurs en poudre avec ou sans matériaux isolants sensibles à la tension, p. ex. varistances
• H01C 17/00 - Appareils ou procédés spécialement adaptés à la fabrication de résistances
• H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives

Abrégé

A scan driver includes stage circuits, wherein each of the stage circuits includes a first transistor, wherein a first electrode thereof is coupled to a first node, a second electrode thereof is coupled to an input carry line, and a gate electrode thereof is coupled to a first clock line; and a capacitor, wherein a first electrode thereof is coupled to the first node and a second electrode thereof is coupled to a second node, wherein the second node is coupled to an output carry line, and the second node is selectively coupled to one of a first power voltage line and a second power voltage line.

Classes IPC  ?

• G09G 3/3266 - Détails des circuits de commande pour les électrodes de balayage
• G09G 3/3233 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED] organiques, p. ex. utilisant des diodes électroluminescentes organiques [OLED] utilisant une matrice active avec un circuit de pixel pour commander le courant à travers l'élément électroluminescent

Abrégé

The present invention is to provide multilayered multiple quantum dot-doped nanoparticles, each of the multiple quantum dot-doped nanoparticles has a structure consisting of an inorganic core particle, a quantum dot-embedded layer, and a silica/quantum dot composite shell. The multiple quantum dot-doped nanoparticles can be used to detect biomolecules with improved quantum yield (QY) and brightness while maintaining a large area covered by the quantum dots and stable bonds of the quantum dots. Therefore, the multiple quantum dot-doped nanoparticles are suitable for bioapplications, including bioplatforms and highly sensitive methods for detecting biomolecules.

Classes IPC  ?

• C09K 11/02 - Emploi de substances particulières comme liants, revêtements de particules ou milieux de suspension
• C09K 11/88 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du sélénium, du tellure ou des chalcogènes non spécifiés
• G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées

Abrégé

In the present invention, among blood metabolites, amino acids, organic compounds and oxylipins that were statistically significantly differentiated from the control group, were selected from type 2 diabetes patients. Specifically, asparagine, aspartic acid, glutamic acid, cysteine, lysine, citric acid, and uric acid, and 12-oxo ETE, 15-oxo ETE, 9-oxo ODE, and 20-carboxy leukotriene B4, which are oxylipins, were confirmed to have cutoff values of AUC>0.7. In addition, the blood metabolites showed a significant difference between a DME patient group and a non-DME patient group, and thus were confirmed to be usable for accurate diagnosis of DME.

Classes IPC  ?

• G01N 30/72 - Spectromètres de masse
• G01N 30/88 - Systèmes intégrés d'analyse, spécialement adaptés à cet effet, non couverts par un seul des groupes
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention relates to a method for producing mesenchymal stem cells from pluripotent stem cells and to mesenchymal stem cells produced by the method. The present invention enables mesenchymal stem cells having an excellent proliferation rate while having superior intrinsic biological activity to be obtained in high yield by sequentially performing three-dimensional suspension culture by using pluripotent stem cells, particularly induced pluripotent stem cells (iPSCs), as starting cells, and adherent culture of cell aggregates formed through same. In addition, mesenchymal stem cells produced by the method of the present invention demonstrate high efficiency of differentiation into bone and cartilage and have excellent anti-inflammatory activity, and thus can be usefully used as compositions for treatment of bone diseases, cartilage diseases, or inflammation and autoimmune diseases.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• A61P 19/00 - Médicaments pour le traitement des troubles du squelette
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

The present invention relates to a method for producing extracellular vesicles from three-dimensionally cultured stem cells, and the method of the present invention can produce stem cell-derived extracellular vesicles with a high yield by the orbital shaking culture of stem cell aggregates in the presence of TGF-β and thus can be advantageously used in an industrial scale mass-production process of exosomes that can be utilized as a pharmaceutical ingredient substituting for a cell therapeutic agent. Furthermore, the exosomes obtained by the method of the present invention have significantly improved immunoregulatory functions compared with exosomes produced by a conventional method, and therefore can also be applied as an excellent therapeutic composition for various inflammations or autoimmune diseases.

Classes IPC  ?

• C12N 5/0775 - Cellules souches mésenchymateusesCellules souches dérivées du tissu adipeux
• C12M 1/32 - Inoculateur ou échantillonneur du type à champs multiples ou en continu
• C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• A61K 35/28 - Moelle osseuseCellules souches hématopoïétiquesCellules souches mésenchymateuses de toutes origines, p. ex. cellules souches dérivées de tissu adipeux
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques

Abrégé

The present invention relates to an influenza virus surface protein-derived recombinant hemagglutinin (HA) protein forming a trimer, and a use thereof, and, specifically, to: a recombinant vector for producing an influenza virus surface protein-derived HA protein forming a trimer; a transformant transformed with the recombinant vector; a method for producing the influenza virus surface protein-derived HA protein forming a trimer, by using the recombinant vector; the influenza virus surface protein-derived HA protein forming a trimer, produced by the method; and a use thereof for preventing, alleviating, or treating influenza virus infection diseases.

Classes IPC  ?

• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
• C07K 14/005 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de virus

Abrégé

A display panel, a pixel circuit, and a display device are disclosed. The display panel includes sub-pixels and a driver driving the sub-pixels. Each sub-pixel includes: an emission element; a first transistor configured to generate a driving current; a constant current control circuit configured to receive a reference voltage and a bias voltage for setting a value of the driving current and including a first capacitor configured to store a first compensation voltage generated by adding a threshold voltage of the first transistor to a difference between the bias voltage and the reference voltage; and a pulse width control circuit configured to receive a data voltage used to determine an emission duration of the emission element and including a second transistor configured to control a pulse width of the driving current according to the data voltage and a second capacitor configured to store a second compensation voltage corresponding to a threshold voltage of the second transistor.

Classes IPC  ?

• G09G 3/32 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED]

Abrégé

A display panel includes sub-pixels each including a light-emitting element and a pixel circuit including a first transistor and a second transistor; a timing control unit to generate bias data based on first characteristic information of the first transistor, and generate correction data based on second characteristic information of the second transistor; and a data sensing driving unit configured to receive the bias data and the correction data, and output a bias voltage and a grayscale voltage to the pixel circuit. The pixel circuit includes the first transistor to output a driving current to the light-emitting element; a first driving circuit to control a magnitude of the driving current based on the bias voltage; and a second driving circuit including the second transistor and configured to control a pulse width of the driving current based on the grayscale voltage.

Classes IPC  ?

• G09G 3/36 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice en commandant la lumière provenant d'une source indépendante utilisant des cristaux liquides
• H03K 3/0233 - Circuits bistables
• G09G 3/32 - Dispositions ou circuits de commande présentant un intérêt uniquement pour l'affichage utilisant des moyens de visualisation autres que les tubes à rayons cathodiques pour la présentation d'un ensemble de plusieurs caractères, p. ex. d'une page, en composant l'ensemble par combinaison d'éléments individuels disposés en matrice utilisant des sources lumineuses commandées utilisant des panneaux électroluminescents semi-conducteurs, p. ex. utilisant des diodes électroluminescentes [LED]

Abrégé

Disclosed herein are a refrigerator, a method of controlling the same, and a refrigerator system including the refrigerator. The refrigerator includes a controller for inputting information on food and controlling the temperature of a supercooling compartment based on the input information, thereby realizing a storage condition optimized for food. The information on the food includes food type and food load information. By determining a storage temperature and the amount of supplied cold air according to the food, it is possible to store the food in a fresh state for a relatively long period of time.

Classes IPC  ?

• F25D 29/00 - Disposition ou montage de l'appareillage de commande ou de sécurité
• F25D 23/12 - Aménagements des compartiments annexes aux compartiments de refroidissementRéfrigérateurs combinés avec un autre appareil, p. ex. une cuisinière
• F25D 17/06 - Dispositions pour la circulation des fluides de refroidissementDispositions pour la circulation de gaz, p. ex. d'air, dans les enceintes refroidies pour la circulation de gaz, p. ex. convection naturelle par circulation d'air forcée
• F25D 17/08 - Dispositions pour la circulation des fluides de refroidissementDispositions pour la circulation de gaz, p. ex. d'air, dans les enceintes refroidies pour la circulation de gaz, p. ex. convection naturelle par circulation d'air forcée en utilisant des conduits

Abrégé

The present invention relates to an extinguishing composition and comprises an extinguishing material and a capsule containing the extinguishing material, and the extinguishing material comprises calcium bromide (CaBr2).

Classes IPC  ?

• A62D 1/00 - Compositions pour éteindre les incendiesEmploi de produits chimiques pour éteindre les incendies
• B01J 13/04 - Fabrication de microcapsules ou de microbilles par des procédés physiques, p. ex. séchage, pulvérisation
• H01M 10/42 - Procédés ou dispositions pour assurer le fonctionnement ou l'entretien des éléments secondaires ou des demi-éléments secondaires

Abrégé

The present invention relates to a composition for preventing, treating, and alleviating atopic dermatitis, comprising AB1711, which is a flavone-resveratrol conjugate compound, or a salt thereof, wherein the composition can prevent, treat, and alleviate atopic dermatitis by inhibiting EGR-1, which is a transcription factor involved in the expression of POMC that is a precursor of various cytokines, chemokines, and beta-endorphins that cause atopic dermatitis.

Classes IPC  ?

• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
• A61Q 19/00 - Préparations pour les soins de la peau

Abrégé

Provided are a flame-retardant member, a method for manufacturing such flame-retardant member, and a secondary battery module and a secondary battery pack comprising such flame-retardant member, the flame-retardant member blocking flames from spreading any further when a fire breaks out while using a lithium secondary battery, thereby enabling safety of use of the secondary battery to be obtained. The flame-retardant member, proposed in the present invention, is a composite pad formed by laminating two or more polymer resin monolayer films each comprising a fire-extinguishing material having a different fire-extinguishing and flame-retardant substrate from the other. The composite pad comprises a first polymer resin monolayer film and a second polymer resin monolayer film, wherein, compared to the second polymer resin monolayer film, the first polymer resin monolayer film comprises a fire-extinguishing material which reacts at a lower temperature range.

Classes IPC  ?

• B32B 27/18 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers
• H01M 50/24 - MonturesBoîtiers secondaires ou cadresBâtis, modules ou blocsDispositifs de suspensionAmortisseursDispositifs de transport ou de manutentionSupports caractérisés par les propriétés physiques des boîtiers ou des bâtis, p. ex. dimensions adaptés pour protéger les batteries de leur environnement, p. ex. de la corrosion
• C09K 21/14 - Substances macromoléculaires
• A62D 1/00 - Compositions pour éteindre les incendiesEmploi de produits chimiques pour éteindre les incendies
• A62C 3/16 - Prévention, limitation ou extinction des incendies spécialement adaptées pour des objets ou des endroits particuliers dans les installations électriques, p. ex. chemins de câbles
• B32B 27/28 - Produits stratifiés composés essentiellement de résine synthétique comprenant des copolymères de résines synthétiques non complètement couverts par les sous-groupes suivants
• C08K 3/22 - OxydesHydroxydes de métaux
• C08K 3/16 - Composés contenant des halogènes
• C08K 3/016 - Agents ignifugeants

Abrégé

Disclosed is a method of tracking an object and apparatuses performing the same, the method including generating a plurality of candidate particles corresponding to an object in a video frame to track the object, and tracking the object by generating optimal particles corresponding to a position of the object in the video frame based on similarities of the plurality of candidate particles with respect to the object.

Classes IPC  ?

• G06T 7/20 - Analyse du mouvement
• G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques
• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06N 3/08 - Méthodes d'apprentissage

Abrégé

In a method for producing acetoin, butanediol, or butanol from ethanol according to the present invention, a cell-free catalysis method was used by designing an artificial synthetic pathway so that proteins of NOX, EtDH, FLS, BDH, and DDH and variant proteins thereof exhibit cascade catalytic activity as enzymes. Compared to existing fermentation methods using microorganisms, the production method according to the present invention does not require cell growth and has a short synthetic pathway, a fast reaction rate, high yield and productivity, adjustment of targeted reaction conditions is convenient, and butanol may be effectively produced. Moreover, same may be reused numerous times by fixing the proteins to nano-particles, and are also effective for producing acetoin, butanediol, or butanol, thus being economical. Therefore, the production method may be usefully adopted in the relevant industries requiring acetoin, butanediol, or butanol.

Classes IPC  ?

• C12N 9/88 - Lyases (4.)
• C12N 9/00 - Enzymes, p. ex. ligases (6.)ProenzymesCompositions les contenantProcédés pour préparer, activer, inhiber, séparer ou purifier des enzymes
• C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
• C12P 7/18 - Polyols
• C12P 7/26 - Cétones
• C12P 7/16 - Butanols
• C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)

Abrégé

A hair perm forming method using electrolyzed water multiple times or for a predetermined period of time or more of the present invention was revealed to have effects that cause very little damage to the hair to enable repeated treatments, enable perming of damaged hair and blonde hair compared with existing methods, show oxidative power higher than that of hydrogen peroxide, cause less hair damage, suppress dandruff bacteria, and significantly decrease the elution of dyes after perming. Therefore, the hair perm forming method using electrolyzed water multiple times or for a predetermined period of time or more of the present invention can be advantageously used as a method capable of effectively forming a perm without harm to the human body in the field of hair perm forming. In addition, the washing of dyed and permed hair, dyed hair, and bleached hair with electrolyzed water, compared with washing with distilled water, has advantages in that the tensile strength of hair is maintained and the dye loss from the dyed hair is less.

Classes IPC  ?

• A61K 8/96 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des produits de constitution indéterminée ou leurs dérivés
• A61Q 5/04 - Préparations pour onduler de façon permanente ou décrêper les cheveux
• A45D 7/04 - Procédés pour onduler, décrêper ou boucler les cheveux chimiques
• C02F 1/467 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse par désinfection électrochimique
• C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse