Abrégé

A ruthenium-based nano-catalyst for a hydrogen generation reaction having excellent catalytic activity and efficiency by the catalyst surface structure, a method for preparing the same, a hydrogen generation electrode and a water electrolysis system.

Classes IPC  ?

• C25B 11/081 - Métal noble
• C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
• C25B 11/037 - Électrodes constituées de particules
• C25B 11/065 - Carbone

Abrégé

Disposed are a method for preparing cellulose-polyvinyl alcohol fabric with improved surface characteristics, cellulose-polyvinyl alcohol fabric with improved surface characteristics prepared thereby, and fabric for wound healing comprising same. The method for preparing cellulose-polyvinyl alcohol fabric with improved surface characteristics comprises, after preparing a composite including a cellulose-based polymer and a polyvinyl alcohol-based polymer, exposing the composite to an alkali solution. The cellulose-polyvinyl alcohol fabric with improved surface characteristics is prepared using the method for preparing cellulose-polyvinyl alcohol fabric with improved surface characteristics. The fabric for wound healing includes the cellulose-polyvinyl alcohol fabric with improved surface characteristics.

Classes IPC  ?

• D06M 15/333 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone d'alcools non saturés ou de leurs esters d'acétate de vinyleAlcool polyvinylique
• D06B 7/00 - Mercerisage, p. ex. brillantage par mercerisage
• D06M 11/13 - Halogénures d'ammonium ou halogénures d'éléments des groupes 1 ou 11 du tableau périodique
• D06M 11/51 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du soufre, du sélénium, du tellure, du polonium ou leurs composés
• D06M 13/144 - AlcoolsAlcoolates métalliques
• D06M 101/06 - Fibres végétales cellulosiques

Abrégé

The present invention relates to a ternary logic circuit and, more particularly, to a ternary logic circuit using an anti-ambipolar transistor (AAT), and a method for designing a ternary logic circuit. The present invention relates to a ternary logic circuit and a method for designing a ternary logic circuit in which a more efficient ternary logic circuit can be implemented by outputting three states by using three transistors respectively connected to three different voltage sources, and a leakage current can be greatly reduced by using an AAT.

Classes IPC  ?

• H03K 19/094 - Circuits logiques, c.-à-d. ayant au moins deux entrées agissant sur une sortieCircuits d'inversion utilisant des éléments spécifiés utilisant des dispositifs à semi-conducteurs utilisant des transistors à effet de champ
• H03K 19/00 - Circuits logiques, c.-à-d. ayant au moins deux entrées agissant sur une sortieCircuits d'inversion
• H10K 10/46 - Transistors à effet de champ, p. ex. transistors organiques à couche mince [OTFT]
• H10K 71/13 - Dépôt d'une matière active organique en utilisant un dépôt liquide, p. ex. revêtement par centrifugation en utilisant des techniques d'impression, p. ex. l’impression par jet d'encre ou la sérigraphie
• G06F 30/32 - Conception de circuits au niveau numérique

Abrégé

An embodiment of the present invention provides a guide system for correcting the rotational alignment of a femur using artificial intelligence image processing and a method therefor, wherein the guide system comprises: an imaging device for capturing images of affected and the unaffected sides of a patient; an image display device for displaying the affected side image containing the femur coupled with an implant and the unaffected side image containing the normal femur captured by the imaging device; and a user device that acquires an affected side image and an unaffected side image from the affected side and unaffected side images, respectively, and aligns the affected side image with the unaffected side image on the basis of the femur to calculate the rotational angle difference between the fractured femur in the affected side image and the normal femur in the unaffected side image using artificial intelligence image processing, thereby guiding the rotational alignment correction of the affected side.

Classes IPC  ?

• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
• G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
• G06T 3/60 - Rotation d’images entières ou de parties d'image
• G06T 7/30 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images
• G06T 17/20 - Description filaire, p. ex. polygonalisation ou tessellation
• G06T 5/80 - Correction géométrique
• G06T 5/73 - Élimination des flousAccentuation de la netteté
• G06T 3/4053 - Changement d'échelle d’images complètes ou de parties d’image, p. ex. agrandissement ou rétrécissement basé sur la super-résolution, c.-à-d. où la résolution de l’image obtenue est plus élevée que la résolution du capteur
• G06T 5/70 - DébruitageLissage
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures

Abrégé

The present invention relates to a ternary full adder circuit and, more specifically, to a ternary full adder circuit using an anti-ambipolar transistor, and a ternary full adder circuit design method, wherein the ternary full adder circuit is implemented using the anti-ambipolar transistor to implement an intermediate state, so that leakage current generated during a switching operation can be significantly reduced.

Classes IPC  ?

• G06F 30/327 - Synthèse logiqueSynthèse de comportement, p. ex. logique de correspondance, langage de description de matériel [HDL] à liste d’interconnections [Netlist], langage de haut niveau à langage de transfert entre registres [RTL] ou liste d’interconnections [Netlist]
• G06F 30/337 - Optimisation de la conception
• G06F 7/49 - Calculs avec une base différente d'une base 2, 8, 16 ou 10, p. ex. avec une base ternaire, négative ou imaginaire, avec une base mixte
• G06F 7/501 - Semi-additionneurs ou additionneurs complets, c.-à-d. cellules élémentaires d'addition pour une position
• H10K 71/13 - Dépôt d'une matière active organique en utilisant un dépôt liquide, p. ex. revêtement par centrifugation en utilisant des techniques d'impression, p. ex. l’impression par jet d'encre ou la sérigraphie
• G06F 30/32 - Conception de circuits au niveau numérique
• H10K 10/46 - Transistors à effet de champ, p. ex. transistors organiques à couche mince [OTFT]

Abrégé

Disclosed are a three-terminal synapse device which does not include a channel and includes a gate-electrolyte separation layer between a gate layer and an electrolyte layer; a method for manufacturing same, and a method for operating same. The three-terminal synapse device may comprise: an electrolyte layer containing a first metal oxide; a gate layer which is disposed on the electrolyte layer and contains a second metal oxide different from the first metal oxide; a gate capping layer which is in contact with and above the gate layer and contains an electrically conductive material; a source electrode in contact with the electrolyte layer and disposed on a first side surface of the electrolyte layer; and a drain electrode in contact with the electrolyte layer and disposed on a second side surface opposite the first side surface of the electrolyte layer.

Classes IPC  ?

• H10N 70/20 - Dispositifs de commutation multistables, p. ex. memristors
• H10N 70/00 - Dispositifs à l’état solide n’ayant pas de barrières de potentiel, spécialement adaptés au redressement, à l'amplification, à la production d'oscillations ou à la commutation
• G06N 3/063 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens électroniques

Abrégé

The present invention relates to a promoter-dependent AD5 cancer lysis virus expressing an EBV gene BZLF1, and a use thereof. In particular, tumor-specific promoters hTERT, E1A, IRES and E1B were inserted into an Ad5 adenovirus vector and BZLF1 was inserted under a CMV promoter so as to increase the activity of the hTERT promoter in cancer cells, and thus developed an oncolytic virus in which E1A, E1B and BZLF1 are expressed. The oncolytic virus according to the present invention is expected to be effectively used as a third-line cancer therapeutic agent for recurrent and metastatic EBV-positive gastric cancer.

Classes IPC  ?

• C12N 15/86 - Vecteurs viraux
• C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61K 35/761 - Adénovirus
• A61P 35/00 - Agents anticancéreux

Abrégé

A method for generating a three-dimensional digital surface model of the present invention may comprise the steps of: acquiring a multi-view satellite image of a target place; estimating pose information of a satellite camera that captured the multi-view satellite image on the basis of the multi-view satellite image; generating a primary digital surface model of the target place on the basis of the multi-view satellite image and the pose information of the satellite camera; restoring the distortion of the primary digital surface model by means of a three-dimensional homography transformation matrix; calculating a virtual RPC for the multi-view satellite image on the basis of the multi-view satellite image and the three-dimensional homography transformation matrix; and generating a secondary digital surface model of the target place by using the multi-view satellite image and the virtual RPC.

Classes IPC  ?

• G06T 17/05 - Modèles géographiques
• G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
• G06T 5/00 - Amélioration ou restauration d'image
• G06T 3/06 - Mappage topologique de structures de dimension plus élevée sur des surfaces de dimension moins élevée
• G06T 7/215 - Découpage basé sur le mouvement
• G06T 3/18 - Déformation d’images, p. ex. réarrangement de pixels individuellement

Abrégé

A gas analysis device for on-site diagnosis according to the present invention comprises: a gas injection unit into which a sample gas for analysis and a carrier gas for moving the sample gas are injected and which is provided to discharge a portion of the injected sample gas and carrier gas to the outside; a gas separation unit which is supplied with the sample gas and carrier gas merged by the gas injection unit and has a heating member and a cooling member for separating impurities included in the supplied sample gas; a control unit which is connected to the gas separation unit and the gas injection unit and adjusts the amount of the sample gas and carrier gas supplied to the gas injection unit or adjusts the temperature of the sample gas by using at least one of the heating member or the cooling member according to the type of the sample gas supplied to the gas separation unit; and a gas analysis unit for analyzing the sample gas that passes through the gas separation unit.

Classes IPC  ?

• G01N 30/30 - Contrôle des paramètres physiques du fluide vecteur de la température
• G01N 30/02 - Chromatographie sur colonne

Abrégé

A multifunctional biobased waterborne polyurethane composition includes, based on 100 parts by weight of the polyurethane composition, 40 to 50 parts by weight of a polyol, 34 to 42 parts by weight of an isocyanate, 8 to 14 parts by weight of a chain extender, 0.03 to 0.12 parts by weight of a catalyst, and 0.005 to 0.02 parts by weight of a neutralizing agent.

Classes IPC  ?

• C08G 18/64 - Composés macromoléculaires non prévus dans les groupes

Abrégé

The present invention relates to a cellulose-based hydrogel bead preparation method, hydrogel beads prepared thereby, and an absorbent article comprising same, the preparation method enabling hydrogel beads to be washed with water without a separate organic solvent in a post-treatment process and shortening a drying time of the hydrogel beads, thereby enabling excellent economic feasibility and safety. In addition, the hydrogel beads prepared by the preparation method and the absorbent article comprising same may have excellent water absorption capacity and atmospheric water capturing ability while also being biodegradable, thereby being environmentally friendly and easily recyclable.

Classes IPC  ?

• C08J 3/24 - Réticulation, p. ex. vulcanisation, de macromolécules
• C08J 3/12 - Pulvérisation ou granulation
• C08J 3/075 - Gels macromoléculaires
• C08K 5/1515 - Cycles à trois chaînons
• C08K 5/07 - AldéhydesCétones
• C08K 3/22 - OxydesHydroxydes de métaux
• A61L 15/60 - Matériaux gonflant avec les liquides pour former un gel, p. ex. super-absorbants
• A61L 15/28 - Polysaccharides ou leurs dérivés
• A61L 15/62 - Matériaux hydrosolubles ou hydrodégradables
• C09K 17/18 - PrépolymèresComposés macromoléculaires

Abrégé

A manufacturing method of a porous polyimide film, includes: preparing a polyamic acid solution at a concentration of 10 to 30 wt % by dissolving a diamine compound and a dianhydride in a solvent; applying the prepared polyamic acid solution to a substrate to prepare a film and then immersing the same in a non-solvent for 30 minutes to 180 minutes; and taking out the immersed film and thermally curing the same; and a porous polyimide film manufactured thereby.

Classes IPC  ?

• C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08J 9/00 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement
• C08J 9/28 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement par élimination d'une phase liquide d'un objet ou d'une composition macromoléculaire, p. ex. par séchage du coagulum
• C08K 9/02 - Ingrédients traités par des substances inorganiques
• H05K 9/00 - Blindage d'appareils ou de composants contre les champs électriques ou magnétiques

Abrégé

The present invention relates to an ultrasonic odometry measuring device and a method thereof, the ultrasonic odometry measuring device, according to one embodiment, comprising: a data collection unit for collecting sensing data including ultrasonic image data by using a sensor equipped in an underwater robot; an information calculation unit for calculating keyframe selection information on the basis of the collected sensing data; a keyframe calculation unit for, on the basis of the calculated keyframe selection information, calculating, as keyframes, a plurality of image frames among image frames constituting the ultrasonic image data; and a distance travelled calculation unit for calculating the distance travelled by the underwater robot through a Fourier-based image registration process for the keyframes.

Classes IPC  ?

• G01C 22/00 - Mesure de la distance parcourue sur le sol par des véhicules, des personnes, des animaux ou autres corps solides en mouvement, p. ex. en utilisant des odomètres ou en utilisant des podomètres
• G01S 15/89 - Systèmes sonar, spécialement adaptés à des applications spécifiques pour la cartographie ou la représentation
• G06T 7/30 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images
• G06F 17/10 - Opérations mathématiques complexes

Abrégé

The present invention relates to a composition, for preventing, relieving, or treating a muscle weakness-related disease, comprising a celery seed extract. The celery seed extract according to the present invention causes a few or no side effects by using a natural product, may increase muscle mass and muscle strength to not only prevent muscle weakness but also inhibit weight gain and body fat increase, and may reduce serum lipid profiles and hepatotoxicity markers (GOT and GPT), and thus is expected to be utilized for preventing, relieving, or treating muscle weakness-related diseases, metabolic diseases, liver diseases, or the like.

Classes IPC  ?

• A61K 36/23 - Apiaceae ou Umbelliferae (famille de la carotte), p. ex. aneth, cerfeuil, coriandre ou cumin
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire

Abrégé

The present invention provides a photo-charging energy storage device and a manufacturing method therefor. The present invention comprises: a solar cell unit; an energy storage element unit for charging a current that is output from the solar cell unit; and a common electrode for connecting the solar cell unit and the energy storage element unit, wherein the common electrode transports electric charges from the solar cell unit to only the energy storage element unit.

Classes IPC  ?

• H01L 31/053 - Moyens de stockage d’énergie directement associés ou intégrés à la cellule PV, p.ex. condensateur intégré avec une cellule PV
• H01L 31/032 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés non couverts par les groupes
• H01L 31/075 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PIN, p.ex. cellules solaires PIN en silicium amorphe
• H01L 31/0216 - Revêtements
• H10K 85/50 - Pérovskites organiquesPérovskites hybrides organiques-inorganiques [HOIP], p. ex. CH3NH3PbI3
• H10K 30/15 - Dispositifs à semi-conducteurs sensibilisés à large bande interdite, p. ex. TiO2sensibilisé aux colorants
• H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
• H10K 30/50 - Dispositifs photovoltaïques [PV]
• H10K 30/85 - Couches à haute mobilité électronique, p. ex. couches de transport d'électrons ou couches de blocage de trous
• H10K 30/86 - Couches à haute mobilité des trous, p. ex. de transport des trous ou couches de blocage des électrons

Abrégé

The present invention relates to a method for preparing cross-linked hyaluronic acid nanoparticles, comprising forming intermolecular or intramolecular cross-linking by irradiating a hyaluronic acid aqueous solution with an electron beam. There are provided uses of synthesized hyaluronic acid nanoparticles as a contrast agent for tumor diagnosis and a therapeutic agent through the skin permeability confirmed by fluorescence labeling and radioactive labeling by uniformly synthesizing hyaluronic acid nanoparticles having various nano-meter sizes reproducibly under an optimized electronic beam condition.

Classes IPC  ?

• A61K 51/06 - Composés macromoléculaires
• A61K 8/67 - Vitamines
• A61K 8/73 - Polysaccharides
• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
• A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
• A61Q 19/08 - Préparations contre le vieillissement

Abrégé

The present invention relates to a multi-level power conversion system comprising: a reactive power compensation unit provided to compensate for reactive power required by a power system, and including a plurality of legs; and a transformer unit connected between the power system and the reactive power compensation unit, wherein the transformer unit includes a zigzag transformer that provides, to the reactive power compensation unit, a zero sequence current path for balancing energy between the plurality of legs. Accordingly, in a multi-level power conversion system including a star-connected converter, the leg energy balance is controlled by a zero sequence current flow, such that a high voltage margin is secured, thereby stably reinforcing the system against vulnerabilities caused by surges in power supply and demand.

Classes IPC  ?

• H02J 3/18 - Dispositions pour réglage, élimination ou compensation de puissance réactive dans les réseaux
• H02M 7/483 - Convertisseurs munis de sorties pouvant chacune avoir plus de deux niveaux de tension
• H02M 7/493 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande les convertisseurs statiques étant agencés pour le fonctionnement en parallèle

Abrégé

The present invention relates to a composition for alleviating, inhibiting, treating or preventing macular degeneration. The composition according to the present invention has excellent effects of reducing angiogenesis due to macular degeneration and inhibiting vascular leakage, and thus can be used as a therapeutic agent for alleviating or treating macular degeneration, particularly age-related macular degeneration (AMD).

Classes IPC  ?

• A61K 31/401 - ProlineSes dérivés, p. ex. captopril
• A61P 27/02 - Agents ophtalmiques
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs

Abrégé

Disclosed are a method, a device, and a system for processing a degaussing of a ship capable of processing the degaussing even during sailing of the ship. A method for processing a degaussing of a ship disclosed herein, according to one embodiment, comprises the steps of: performing degaussing processing before sailing of a ship in a magnetic processing station; calculating a first compensation current for compensating for a magnetic field generated during sailing of the ship on the basis of ship sailing-related information of the ship; and calculating a second compensation current for compensating for a magnetic field generated during sailing according to occurrence of a preset event during sailing of the ship.

Classes IPC  ?

• B63G 9/06 - Autres aménagements offensifs ou défensifs sur les navires contre sous-marins, torpilles ou mines pour la démagnétisation des navires
• B63B 79/30 - Surveillance des caractéristiques ou des paramètres de fonctionnement des navires en opération pour le diagnostic, les essais ou la prévision de l’intégrité ou des performances des navires
• B63B 79/10 - Surveillance des caractéristiques ou des paramètres de fonctionnement des navires en opération utilisant des capteurs, p. ex. des capteurs de pression, des jauges de contrainte ou des accéléromètres
• G01R 33/02 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques
• G01R 15/20 - Adaptations fournissant une isolation en tension ou en courant, p. ex. adaptations pour les réseaux à haute tension ou à courant fort utilisant des dispositifs galvano-magnétiques, p. ex. des dispositifs à effet Hall
• G01R 33/00 - Dispositions ou appareils pour la mesure des grandeurs magnétiques
• H01L 29/82 - Types de dispositifs semi-conducteurs commandés par la variation du champ magnétique appliqué au dispositif

Abrégé

A composite material reinforcement device may include: a central portion including an edge portion provided to have an inner space having a trapezoidal cross-section with reference to a longitudinal direction, and a partition wall portion dividing the inner space into at least one partition space; and a reinforcement portion located on a top and a bottom of the central portion and integrally molded to cover the central portion, wherein the reinforcement portion includes: a first plate located on the top of the central portion to cover an upper portion of the central portion; a second plate curved to correspond to a shape of the central portion and located at the bottom of the central portion to cover a lower portion of the central portion; and an extension portion in which the first plate and the second plate extend from both ends of the central portion to be bonded to each other.

Classes IPC  ?

• E04H 9/02 - Bâtiments, groupes de bâtiments ou abris conçus pour résister à des situations extérieures anormales, p. ex. à des bombardements, à des séismes ou à des climats extrêmes, ou pour se protéger de ces situations résistant aux séismes ou à l'effondrement du sol

Abrégé

Disclosed are an exterior cover, an electronic device comprising same, and a manufacturing method therefor according to one embodiment. The exterior cover comprises: a first material including recycled aluminum; and a second material coupled to the first material and including a metal having a higher strength than the recycled aluminum, wherein at least one pattern structure may be formed on a surface on which the first material and the second material are coupled. Various other embodiments may be possible.

Classes IPC  ?

• H05K 5/03 - Couvercles ou capots
• H05K 5/04 - Enveloppes métalliques
• H05K 5/00 - Enveloppes, coffrets ou tiroirs pour appareils électriques
• H04M 1/02 - Caractéristiques de structure des appareils téléphoniques
• B22F 7/04 - Fabrication de couches composites, de pièces ou d'objets à base de poudres métalliques, par frittage avec ou sans compactage de couches successives avec une ou plusieurs couches non réalisées à partir de poudre, p. ex. à partir de tôles
• B22F 7/08 - Fabrication de couches composites, de pièces ou d'objets à base de poudres métalliques, par frittage avec ou sans compactage de pièces ou objets composés de parties différentes, p. ex. pour former des outils à embouts rapportés avec une ou plusieurs parties non faites à partir de poudre
• C22C 21/06 - Alliages à base d'aluminium avec le magnésium comme second constituant majeur
• C22C 21/10 - Alliages à base d'aluminium avec le zinc comme second constituant majeur
• B33Y 10/00 - Procédés de fabrication additive
• B22F 10/28 - Fusion sur lit de poudre, p. ex. fusion sélective par laser [FSL] ou fusion par faisceau d’électrons [EBM]

Abrégé

The present invention relates to a super-water-repellent three-dimensional structure using capillary-force-induced aggregation, and a manufacturing method therefor. Provided are a super-water-repellent three-dimensional structure using capillary-force-induced aggregation, and a manufacturing method therefor, the method comprising: an upright hierarchical column formation step of using polydimethylsiloxane, which is an elastic material, so as to form an upright hierarchical column structure in which a plurality of protrusions are formed on the top of a column that is narrow at the top and wide at the bottom; an aggregation induction step of applying polyvinyl alcohol to the surface of the upright hierarchical column structure and drying same, thereby inducing aggregation between the protrusions by means of capillary force; a curing step of applying polydimethylsiloxane to the protrusions, and curing same to fix same in an aggregated state; a water repellency provision step of applying a hydrophobic wax solution to the front surface of the upright hierarchical column structure; and a coating step of coating the protrusions with a polydopamine aqueous solution, which is a hydrophilic solution.

Classes IPC  ?

• C08J 7/054 - Formation de revêtements anti-buée ou anti-gouttes
• C08J 7/04 - Revêtement
• C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
• B29C 33/38 - Moules ou noyauxLeurs détails ou accessoires caractérisés par la matière ou le procédé de fabrication
• B29C 33/40 - Matière plastique, p. ex. mousse ou caoutchouc
• C08L 83/04 - Polysiloxanes
• C08L 29/04 - Alcool polyvinyliqueHomopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
• C09D 5/16 - Peintures antisalissuresPeintures subaquatiques
• C09D 165/00 - Compositions de revêtement à base de composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principaleCompositions de revêtement à base de dérivés de tels polymères
• C09D 191/06 - Cires

Abrégé

The present invention relates to a 3D microstructure replication method using a Poisson effect. According to the present invention, provided is a 3D microstructure replication method using a Poisson effect, comprising: a soft mold preparation step for forming a soft mold by transferring a superelastic material to a master mold by a soft lithography method; a resin application step for applying a resin to the soft mold; a compression step for applying vertical pressure to the upper surface of the soft mold and transforming the shape of the soft mold by using the Poisson effect due to the vertical pressure; a resin curing step for curing the resin by applying heat or ultraviolet rays to the transformed soft mold to generate a 3D microstructure; and a releasing step for removing the vertical pressure to restore the shape of the soft mold and releasing the 3D microstructure.

Classes IPC  ?

• G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
• B29C 59/02 - Façonnage de surface, p. ex. gaufrageAppareils à cet effet par des moyens mécaniques, p. ex. par pressage

Abrégé

A gadolinium-based compound and an MRI contrast agent comprising same are disclosed. The gadolinium-based compound may be a DO3A-based gadolinium compound bound to protocatechuic acid. The MRI contrast agent may comprise the compound. In addition, disclosed is a pharmaceutical composition for preventing or treating neuroinflammatory diseases, comprising the compound or a pharmaceutically acceptable salt thereof.

Classes IPC  ?

• A61K 49/10 - Composés organiques
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• C07F 5/00 - Composés contenant des éléments des groupes 3 ou 13 du tableau périodique

Abrégé

The present invention relates to a boronic acid functional pressure-sensitive adhesive. More specifically, the present invention provides a method for manufacturing a boronic acid functional pressure-sensitive adhesive, the method comprising the steps of: synthesizing a scaffold pressure-sensitive adhesive by reacting butyl acrylate with glycidyl methacrylate; and synthesizing a boronic acid pressure-sensitive adhesive by reacting a scaffold pressure-sensitive adhesive with 4-mercaptophenylboronic acid. In addition, the present invention provides a boronic acid functional pressure-sensitive adhesive comprising a boronic acid group and a butyl group. In addition, the present invention provides a functional coating material and an antifouling coating composition, comprising the boronic acid pressure-sensitive adhesive according to the present invention.

Classes IPC  ?

• C09J 143/00 - Adhésifs à base d'homopolymères ou de copolymères de composés possédant un ou plusieurs radicaux aliphatiques non saturés, chacun ne contenant qu'une seule liaison double carbone-carbone et contenant du bore, du silicium, du phosphore, du sélénium, du tellure ou un métalAdhésifs à base de dérivés de tels polymères
• C09D 5/14 - Peintures contenant des biocides, p. ex. fongicides, insecticides ou pesticides
• C09D 5/16 - Peintures antisalissuresPeintures subaquatiques
• C09D 143/00 - Compositions de revêtement à base d'homopolymères ou de copolymères de composés possédant un ou plusieurs radicaux aliphatiques non saturés, chacun ne contenant qu'une seule liaison double carbone-carbone et contenant du bore, du silicium, du phosphore, du sélénium, du tellure ou un métalCompositions de revêtement à base de dérivés de tels polymères
• C08F 8/42 - Introduction d'atomes métalliques ou de groupes contenant des atomes métalliques
• C08F 220/32 - Esters contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle contenant des radicaux époxyde

Abrégé

Polyscias fruticosaPolyscias fruticosaPolyscias fruticosa can be presented as a novel high value-added farm income crop.

Classes IPC  ?

• A61K 36/25 - Araliaceae (famille du ginseng), p. ex. lierre, aralia, schefflera ou tétrapanax
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A61P 31/04 - Agents antibactériens
• A61P 31/12 - Antiviraux
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés

Abrégé

The present invention relates to a dual-mode probe for detecting of hydrogen sulfide and use thereof and, more specifically to a dual-mode probe that has excellent blood-brain barrier permeability and is capable of fluorescence and nuclear imaging and a use thereof for detecting hydrogen sulfide.

Classes IPC  ?

• A61K 51/04 - Composés organiques
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations
• C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
• C07F 1/08 - Composés du cuivre

Abrégé

According to the present invention, a multi-detection analysis method of a biological sample includes a step of preparing a plurality of a magnetic encoded microparticles encoded in different types and introducing the plurality of a magnetic encoded microparticles into a sample of an analysis target, a step of acquiring a video of the sample in a state where the sample is exposed to a rotating magnetic field, a step of inputting a time-series image included in the video into a pre-trained deep learning algorithm, analyzing rotation pattern characteristics of each magnetic encoded microparticle in the video over time through the deep learning algorithm, and classifying each magnetic encoded microparticle, and a step of multi-detecting a plurality of types of target materials in the sample based on a classification result of each magnetic encoded microparticle in the video.

Classes IPC  ?

• G06V 20/69 - Objets microscopiques, p. ex. cellules biologiques ou pièces cellulaires
• G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G06T 7/20 - Analyse du mouvement
• G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux

Abrégé

The present invention relates to a multipurpose biodegradable cleaner and a method for producing same. The multipurpose biodegradable cleaner uses a 100% biodegradable fabric to address waste and environmental pollution issues caused by existing non-degradable fabrics, and has a non-slip layer on the rear surface of an anti-fog layer, thus providing less discomfort during use and providing functionality for touch-up makeup, and can therefore contribute to user convenience and portability. In addition, the present invention contains hyaluronic acid, ceramide, flower acid, and a natural extract and can thus provide a high degree of moisturization and keratolytic, anti-inflammatory, and antibacterial effects and the like, and can help provide the user with psychological stability, stress relief, fatigue recovery, and the like by means of aromatic particles in a fragrance capsule.

Classes IPC  ?

• D06M 23/12 - Procédés dans lesquels l'agent traitant est incorporé dans des microcapsules
• D06M 15/693 - Traitement des fibres, fils, filés, tissus ou articles fibreux faits de ces matières, avec des composés macromoléculairesUn tel traitement combiné avec un traitement mécanique avec du caoutchouc naturel ou synthétique ou leurs dérivés
• D06M 11/73 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du carbone ou ses composés
• D06M 11/79 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexesUn tel traitement combiné avec un traitement mécanique, p. ex. mercerisage avec du silicium ou ses composés avec du dioxyde de silicium, des acides siliciques ou leurs sels
• D06M 11/46 - Oxydes ou hydroxydes d'éléments des groupes 4 ou 14 du tableau périodiqueTitanatesZirconatesStannatesPlombates
• D06M 23/06 - Procédés dans lesquels l'agent traitant est dispersé dans un gaz, p. ex. aérosols
• D06M 101/06 - Fibres végétales cellulosiques
• D06M 101/32 - Polyesters
• D06M 101/18 - Fibres synthétiques consistant en composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone

Abrégé

The present invention relates to an optoelectronic module using spatial light modulators and an optical computer comprising same. The optoelectronic module using the spatial light modulators comprises: a plurality of first light sources; a plurality of first lenses that reduce the divergence angles of light rays emitted from the first light sources; a plurality of spatial light modulators that adjust the intensity of light rays that pass through the first lenses; a plurality of light detectors that acquire a current value dependent on light intensity; and a lens unit that focuses the light rays, emitted from the first different light sources, onto one of the light detectors. The lens unit carries out the function of calculating the convolution of a light source array and a pixel array of the spatial light modulators by using the function of focusing the light rays, emitted from the first different light sources, onto the one light detector.

Classes IPC  ?

• G06N 3/067 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens optiques
• G06N 3/0464 - Réseaux convolutifs [CNN, ConvNet]
• G06E 3/00 - Dispositifs non prévus dans le groupe , p. ex. pour traiter des données analogiques hybrides
• G02B 26/02 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander l'intensité de la lumière
• G02B 27/09 - Mise en forme du faisceau, p. ex. changement de la section transversale, non prévue ailleurs

Abrégé

The present invention relates to a ferritin nanocage fused with a LAG3 binding peptide and use thereof as an anticancer immunotherapeutic agent, in which, by respectively fusing peptides that bind to immune checkpoint receptor LAG3 (LAG3pep1: CIRNDPAVC and LAG3pep2: CSVLNASGC) to loops protruding from the surface of human ferritin to form a cage, a nanocage in which 24 LAG3 binding peptides are displayed was produced. The nanocage of the present invention increased immune activity by specifically binding to LAG3 receptors and blocking LAG3, and exhibited an anticancer effect by effectively targeting brain cancer tissues through BBB. In addition, an immune checkpoint blocking nanocage in which an LAG3 binding peptide and a PD-L1 binding peptide are fused together specifically binds to each receptor, thereby exhibiting a bifunctional immune checkpoint blocking effect. Therefore, the nanocage technology of the present invention is expected as a next-generation drug that overcomes the limitations of immune checkpoint blocking therapy using antibodies.

Classes IPC  ?

• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
• A61K 9/51 - Nanocapsules
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention relates to a bio-implantable actuator and an artificial joint comprising the same and, more specifically, to a bio-implantable actuator and an artificial joint comprising same, the bio-implantable actuator being capable of transmitting motion force and capable of reducing a load applied to a joint, without limiting the degree of freedom of motion of the joint. The bio-implantable actuator according to an embodiment of the present invention comprises: a power unit generating a rotational force; a linear motion unit that is connected to the power unit and converts rotational motion of the power unit into linear motion; and a flexible rod connected to the linear motion unit. In addition, the bio-implantable actuator according to another embodiment of the present invention comprises: a tube having one open end and a hollow portion; a linear motion unit disposed inside the tube; and a flexible rod having one end disposed inside the tube so as to be connected to the linear motion unit and the other end protruding to the outside of the tube.

Classes IPC  ?

• A61F 2/38 - Articulations pour les coudes ou les genoux
• A61F 2/48 - Moyens d'actionnement ou de commande, p. ex. de l'extérieur du corps, commande de sphincters
• A61F 2/30 - Articulations

Abrégé

The present invention relates to a method for manufacturing a Mg/Ti composite, and a metal composite manufactured thereby, the method immersing, in a molten metal that contains (Mg) and calcium (Ca), a precursor alloy (Ti-X) that contains titanium (Ti) and a metal (X), which is miscible with the molten metal so as to be dissolved into the molten metal, wherein the Ca alloy element, which is included in a molten Mg-Ca alloy, is highly miscible with Cu so as to promote dealloying behavior by which Cu is dissolved into the molten metal, thereby greatly reducing process time, is dissolved in Mg matrix so as to increase the volume fraction of the Mg matrix in the composite, and reduces the coarsening rate of Ti and, simultaneously, improves the strength of the composite through solid-solution strengthening of the Mg matrix.

Classes IPC  ?

• C22C 1/02 - Fabrication des alliages non ferreux par fusion
• C22C 23/00 - Alliages à base de magnésium

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating hearing loss, the composition containing berberine chloride as an active ingredient. The pharmaceutical composition was found to effectively inhibit hair cell apoptosis caused by reactive oxygen species and exhibit an excellent protective effect on hair cells, and thus can be effectively used as a drug or health supplement for preventing or treating hearing loss.

Classes IPC  ?

• A61K 31/4375 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. quinolizines, naphtyridines, berbérine, vincamine
• A61P 27/16 - Otologiques
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs

Abrégé

The present invention relates to a method for manufacturing a Mg/TiAl composite, and a Mg/TiAl composite manufactured thereby, the method comprising the steps of: (a) immersing, in a molten metal containing magnesium (Mg), a precursor alloy (Ti-X) containing a metal (X), which is miscible with titanium (Ti) and is to be dissolved in the molten metal, thereby manufacturing a Mg/Ti composite; (b) manufacturing a titanium (Ti) porous structure from the Mg/Ti composite; and (c) immersing the titanium (Ti) porous structure in a molten Mg-Al alloy, thereby manufacturing a Mg/TiAl composite. A magnesium matrix material is removed from a Mg-Ti composite manufactured through liquid metal dealloying (LMD), and then aluminum alloying is performed using the molten Mg-Al alloy, and thus a Mg/TiAl composite structured to be a three-dimensionally interconnected, in which an element such as copper (Cu) contained in the precursor alloy does not remain and which has excellent physical properties, can be manufactured.

Classes IPC  ?

• C22C 1/02 - Fabrication des alliages non ferreux par fusion
• C22C 23/00 - Alliages à base de magnésium
• C22C 1/08 - Alliages poreux avec pores ouverts ou fermés

Abrégé

The present invention relates to a novel compound comprising an ester group and uses thereof and, more particularly, to a novel compound that exhibits excellent visualization ability in a tumor by using the difference in activity of esterase for each organ in the body, and to uses therefor for diagnosing or treating cancer. A novel compound of chemical Formulas 1 to 8 according to the present invention exhibits selectivity according to the difference in activity of esterase for each organ due to ester residue in a structure, and thus is extremely effective in visualizing pancreatic cancer, etc.

Classes IPC  ?

• C07F 1/08 - Composés du cuivre
• A61K 51/04 - Composés organiques
• A61K 51/12 - Préparations contenant des substances radioactives utilisées pour la thérapie ou pour l'examen in vivo caractérisées par un aspect physique particulier, p. ex. émulsion, microcapsules, liposomes

Abrégé

The present disclosure relates to ultra-high speed digital signal integrity improving structures. Each structure in the present disclosure includes a first unit structure and a second unit structure of the same or different shapes arranged to face each other on the left and right sides along a longitudinal direction of a balanced line, centered around a coplanar stripline (CPS) or parallel stripline (PSL) formed on a substrate. At least one of the first unit structure and the second unit structure includes a first side close to the balanced line and having a linear or curve shape; a second side facing the first side; and left and right sides connecting the first side and the second side. Here, the width of the first side is less than or equal to that of the second side, the left and right sides have a linear or non-linear slope, and the width from the first side to the second side is configured to change continuously or discontinuously. When the structures of the present disclosure are disposed around a balanced line, it has the advantage of being able to recover the distorted phase autonomously while rejecting a common-mode signal in a frequency band up to 40 GHz or more.

Classes IPC  ?

• H01P 1/00 - Dispositifs auxiliaires
• H01P 3/08 - MicrorubansTriplaques

Abrégé

The present invention relates to a method for manufacturing an imide-based porous film, being capable of pore shape control, in which a porogen is dispersed in a polyamic acid solution to form a porous polyimide film, and the concentrations of the porogen and nanoparticles are adjusted to control pores, thereby manufacturing an imide-based porous film that is heat resistant to high temperatures.

Classes IPC  ?

• C08J 9/26 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement par élimination d'une phase solide d'un objet ou d'une composition macromoléculaire, p. ex. par lessivage
• C08J 9/00 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement
• C08J 5/18 - Fabrication de bandes ou de feuilles
• C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide-acides ou précurseurs similaires de polyimides

Abrégé

Provided is a battery management system including: a battery management device, disposed on a mobile vehicle, for measuring battery information from a battery; a cloud server device for collecting the battery information from the battery management device and storing the battery information, and for, based on determination condition and service command of pre-registered battery management service, if it is determined that there exists battery information matching the determination condition, controlling a resulting information to be created from the extracted information in accordance with the service command; and a terminal device for receiving and outputting the resulting information.

Classes IPC  ?

• G06F 1/3212 - Surveillance du niveau de charge de la batterie, p. ex. un mode d’économie d’énergie étant activé lorsque la tension de la batterie descend sous un certain niveau

Abrégé

A geometric phase optical element according to the present invention comprises: an optically anisotropic material; and a phase retardation layer with a quarter-waveplate phase retardation amount, wherein: the phase retardation layer receives incident light and outputs modulated light and unmodulated light; and the modulated light and the unmodulated light, which are output from the phase retardation layer, may have the same intensity.

Classes IPC  ?

• G02B 5/30 - Éléments polarisants
• G02B 5/02 - DiffuseursÉléments afocaux
• G02B 3/00 - Lentilles simples ou composées

Abrégé

The present invention relates to peptides binding to LAG-3 and a use thereof in cancer immunotherapy and anticancer applications. The peptides of the present invention specifically bind to and inhibit LAG-3, thereby activating the function of immune cells against cancer cells and exhibiting anticancer effects. Using phage peptide display technology targeting cells with high expression of human LAG-3 protein, two peptides, LAG-3Pep-1 and LAG-3Pep-2, which were found to highly bind to the protein, were selected as the peptides of the present invention. These peptides were confirmed to bind to both human and mouse LAG-3 and inhibit its function. The peptides of the present invention showed effects similar to those of antibodies and were relatively stable in the bloodstream, indicating high potential as future cancer immunotherapeutics.

Classes IPC  ?

• C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
• C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
• A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
• A61K 49/00 - Préparations pour examen in vivo
• A61K 51/08 - Peptides, p. ex. protéines
• A61P 35/00 - Agents anticancéreux
• A61K 38/00 - Préparations médicinales contenant des peptides
• G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The double-membrane composite for intestinal anastomosis protection of the present invention comprises an inner membrane that contacts biological tissue and is composed of a bio-friendly, biodegradable polymer having a functional group introduced thereinto; and an outer membrane formed on one surface of the inner membrane and composed of a cross-linked anti-adhesive biodegradable polymer. According to the present invention, the intestinal anastomosis site is protected by the inner membrane of the mesh, while the outer membrane of the mesh can prevent unnecessary adhesion to other organs.

Classes IPC  ?

• A61L 31/04 - Matériaux macromoléculaires
• A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose
• A61L 31/14 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61L 27/14 - Matériaux macromoléculaires
• A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques
• A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux

Abrégé

The present invention relates to a photocatalyst and a preparation method therefor. The photocatalyst according to the present invention comprises titanium dioxide with a bronze crystal phase and an anatase crystal phase so as to have high photoactivity, and thus is suitable for removing odors and toxic gases. In addition, the titanium dioxide included in the photocatalyst, according to the present invention, has a novel crystal phase having a charge separation effect superior to those of other crystal phases, and thus has improved photoactivity. Additionally, the photocatalyst of the present invention has high photoactivity, and thus is suitable for removing odors and toxic gases. In addition, the photocatalyst of the present invention has excellent durability against catalytic poisons formed on the surface of a catalyst during removal of VOCs and toxic gases (acetaldehyde, isovaleraldehyde, isovaleric acid and toluene).

Classes IPC  ?

• B01J 35/39 - Propriétés photocatalytiques
• B01J 21/06 - Silicium, titane, zirconium ou hafniumLeurs oxydes ou hydroxydes
• B01J 35/23 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général caractérisés par leur état non solide sous forme colloïdale
• B01J 37/10 - Traitement thermique en présence d'eau, p. ex. de vapeur d'eau

Abrégé

A light-collecting device according to an embodiment has a robot manipulator and comprises: a sensing portion for acquiring information regarding the position and direction of the light-collecting device; a measurement portion for measuring the actual incident angle of the sun; a computation portion for assessing the theoretical position value of the sun by using information from the sensing portion, the computation portion comprising a first computation member for calculating the position and direction of the sun on the basis of the sensing portion's GPS and compass sensor values, a second computation member for reading the measurement portion's light-dependent resistor 16-array sensor values so as to calculate the offset from the actual position and direction of the sun, and a third computation member for solving inverse kinematics such that an end-effector faces in the position and direction of the sun calculated by the first or second computation member; a controller for controlling the robot manipulator by using information from the computation portion and the measurement portion; a heat-collecting portion disposed on an end of the robot manipulator so as to collect sunlight, thereby heating a focal point; and a battery. The controller may precisely correct the robot manipulator such that the plane of the heat-collecting portion is perpendicular to the incident angle of the sun.

Classes IPC  ?

• F24S 30/48 - Agencements pour mouvoir ou orienter des modules de collecteurs de chaleur solaire pour le déplacement en rotation avec trois axes de rotation ou plus ou avec de multiples degrés de liberté
• F24S 50/20 - Agencements pour commander les collecteurs de chaleur solaire pour le suivi
• F24S 23/30 - Agencements pour concentrer les rayons solaires pour les collecteurs de chaleur solaire avec des lentilles
• G01J 1/42 - Photométrie, p. ex. posemètres photographiques en utilisant des détecteurs électriques de radiations
• B25J 11/00 - Manipulateurs non prévus ailleurs
• B25J 9/06 - Manipulateurs à commande programmée caractérisés par des bras à articulations multiples
• B25J 13/08 - Commandes pour manipulateurs au moyens de dispositifs sensibles, p. ex. à la vue ou au toucher

Abrégé

The present invention relates to a transition metal complex catalyst composition for polymerization of a monomer having a cyclic ester group and a method of producing a polymer using the same. More particularly, the invention provides a catalyst composition comprising a transition metal complex containing aminopyridine and aminoquinoline ligands, and a method of producing a polymer having high heterotacticity with high conversion rate even at room temperature by using the same. Since the catalyst composition for polymerization of a monomer having a cyclic ester group according to the invention comprises a transition metal compound that is chemically stable in air, it is capable of effectively producing a polymer having high heterotacticity (Pr) with high conversion rate at room temperature or below room temperature without satisfying high-temperature conditions.

Classes IPC  ?

• C08G 63/82 - Procédés de préparation caractérisés par le catalyseur utilisé
• C07F 1/08 - Composés du cuivre
• C07F 3/06 - Composés du zinc
• C07F 15/06 - Composés du cobalt
• C08G 63/08 - Lactones ou lactides

Abrégé

Provided is a spine fixing device including: a base plate; a cage configured to be coupled to the base plate; a first wing plate configured to be coupled to an upper portion of a composite body of the base plate and the cage; and a second wing plate configured to be coupled to a lower portion of the composite body of the base plate and the cage.

Classes IPC  ?

• A61B 17/70 - Dispositifs de mise en position ou de stabilisation de la colonne vertébrale, p. ex. stabilisateurs comprenant un liquide de remplissage dans un implant

Abrégé

The present invention relates to an extracellular vesicle expressing a cytokine and an antibody, a method for producing same, and a use thereof. The present invention provides a method for producing an immune cell expressing both a cytokine and an antibody on membrane surface by transforming them with a first vector encoding a cytokine and a second vector encoding an antibody, and producing their extracellular vesicle expressing both a cytokine and an antibody on the surface. The present invention provides the extracellular vesicle which induces a desired cytokine response in cells that can be targeted with a specific antibody and is safe for the human body while exhibiting excellent anticancer effects. The present invention provides a new cancer treatment means that deliver drugs or physiologically active substances to specific cancer cells by loading a drug or physiologically active substance that exhibits a therapeutic effect on cancer in the extracellular vesicle.

Classes IPC  ?

• A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
• A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
• A61K 38/20 - Interleukines
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention relates to a method for manufacturing a personalized lip retractor, comprising the steps of: collecting, by a collection unit, facial information about a user; detecting, by an analysis unit, a smile line of the user from the facial information and analyzing the smile line; generating, by a generation unit, on the basis of the analyzed smile line, a personalized smile line optimized for the face of the user to correct the smile line of the user; designing, by a design unit, the shape of a personalized lip retractor according to the generated smile line; and manufacturing, by a manufacturing unit, the personalized lip retractor according to the designed shape. Accordingly, a lip retractor that can perform training to induce contraction of relevant muscles to form an aesthetic smile can be provided, and a smile line of an individual user can be analyzed and a lip retractor can be manufactured in the shape of a lip line that is tailored to the individual user according to the result of analyzing the smile line.

Classes IPC  ?

• A61C 13/00 - Prothèses dentairesLeurs procédés de fabrication
• A61C 9/00 - Méthodes de prise d'empreintes spécialement conçues pour les prothèses dentairesPorte-empreintes à cet effet
• G06T 1/00 - Traitement de données d'image, d'application générale
• G06T 7/00 - Analyse d'image
• G16H 30/00 - TIC spécialement adaptées au maniement ou au traitement d’images médicales
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• A45D 44/12 - Protège-oreilles, protège-figure ou protège-lèvres
• A61C 5/90 - Protections buccales à utiliser durant le traitement, p. ex. protège-lèvres ou protège-bouche
• A61C 5/00 - Obturation ou recouvrage des dents

Abrégé

The present invention relates to a sensor calibration method for a multi-axis force torque sensor having a maximum of n axes, and being capable of measuring vertical force on n/2 axes and measuring horizontal torque on the n/2 axes, and, specifically, comprises: a first step of preparing test reference data of the multi-axis force torque sensor; a second step of obtaining sensor output values measured on the n axes provided in the multi-axis force torque sensor by using, as an input value, the test reference data prepared through the first step; a third step of calculating the linear relationship of the input value and the sensor output value on each axis for force and torque by using the sensor output values obtained through the second step; and a fourth step of calculating, on the basis of the linear relationship calculated through the third step, an input value corresponding to the sensor output value obtained through the second step, and then comparing the calculated input value to an actual input value so as to calculate a correlation determinant according to a correlation between the respective axes.

Classes IPC  ?

• G01L 25/00 - Test ou étalonnage des appareils pour la mesure des forces, du couple, du travail, de la puissance ou du rendement mécanique
• G01L 5/16 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques pour la mesure de plusieurs composantes de la force
• G01L 5/00 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques
• G06F 17/10 - Opérations mathématiques complexes

Abrégé

The present invention relates to a wire-based variable link robot manipulator, which can have an expanded work area through a change in link length, can be miniaturized, and uses a wire-based actuator during implementation of a link length-adjustable mechanism so as to reduce the weight of a link and, simultaneously, reduce the required torque of a motor by reducing the weight of the link, and structurally comprises: a first link unit (100) formed of a first body (110) and a second body (120); a second link unit (200) formed of a first body (210) and a second body (220); a third body (300) coupled to the first link unit (100); and a base (600) for supporting the first link unit (100) and the second link unit (200), wherein the first link unit (100) and the second link unit (200) are adjusted in length through the driving of a wire (530), a wire (540) and a wire (570).

Classes IPC  ?

• B25J 9/10 - Manipulateurs à commande programmée caractérisés par des moyens pour régler la position des éléments manipulateurs
• B25J 9/00 - Manipulateurs à commande programmée

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory skin diseases, comprising, as an active ingredient, an Oryza Sativa bran and rice bran extract derived from a CNDH106 rice variety. It has been identified that the Oryza Sativa bran and rice bran extract derived from a CNDH106 rice variety containing large amounts of chrysoeriol-7 and cochlioquinone-9 through artificial crossbreeding exhibits anti-inflammatory activity in human keratinocytes (HaCaT cells), and thus the present invention can be effectively used as a composition for preventing, treating or alleviating inflammatory skin diseases.

Classes IPC  ?

• A61K 36/899 - Poaceae ou Gramineae (famille des céréales), p. ex. bambou, blé ou canne à sucre
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A61K 8/9794 - Liliopsida [monocotylédones]
• A61Q 19/00 - Préparations pour les soins de la peau
• A01H 6/46 - Gramineae ou Poaceae, p. ex. ivraie, riz, blé ou maïs
• A01H 5/10 - Graines

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory bowel disease, comprising, as an active ingredient, an Oryza Sativa bran and rice bran extract derived from a CNDH106 rice variety. It has been identified that the Oryza Sativa bran and rice bran extract derived from a CNDH106 rice variety containing large amounts of chrysoeriol-7 and cochlioquinone-9 through artificial crossbreeding exhibits anti-inflammatory activity in colon cells (caco-2 cells), and thus the present invention can be effectively used as a composition for preventing, treating or alleviating inflammatory bowel disease.

Classes IPC  ?

• A61K 36/899 - Poaceae ou Gramineae (famille des céréales), p. ex. bambou, blé ou canne à sucre
• A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p. ex. cannabinols, méthanthéline
• A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés

Abrégé

The present invention relates to a composition for preventing or treating neurodegenerative diseases or depression, comprising ASM protein or a fragment thereof and, more particularly, to a pharmaceutical or food composition comprising ASM protein or a fragment thereof that exhibits a therapeutic effect on neurodegenerative diseases or depression by inhibiting the activity of ASM protein in plasma.

Classes IPC  ?

• A61K 38/46 - Hydrolases (3)
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
• A61P 25/24 - Antidépresseurs
• A23L 33/17 - Acides aminés, peptides ou protéines

Abrégé

Provided are silica-coated cellulose nanofibers modified with a hydrophobic group capable of improving the mechanical properties of a pressure-sensitive adhesive while maintaining the adhesive performance of the pressure-sensitive adhesive; and a pressure-sensitive adhesive including the same.

Classes IPC  ?

• C08J 7/04 - Revêtement
• C09J 7/38 - Adhésifs sensibles à la pression
• C09J 11/08 - Additifs macromoléculaires

Abrégé

The present disclosure relates to a membrane filter for water and wastewater treatment including a membrane filter, hydrophilic polymers formed on the membrane filter; and quorum quenching microorganisms cross-linked with the membrane filter by the hydrophilic polymer. The quorum quenching microorganisms are attached to the surface of the membrane filter for water and wastewater treatment, resulting in a higher initial permeation pressure than a conventional membrane, but the quorum quenching microorganisms may effectively prevent the phenomenon of quorum sensing, allowing the formation of a biofilm, thereby improving the life of the membrane filter for water and wastewater treatment.

Classes IPC  ?

• B01D 65/08 - Prévention de l'encrassement de la membrane ou de la polarisation par concentration
• B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
• B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
• C02F 1/44 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par dialyse, osmose ou osmose inverse
• C02F 3/12 - Procédés par les boues activées
• C02F 3/34 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les micro-organismes utilisés

Abrégé

The present invention relates to a biomarker composition for the diagnosis of liver diseases. It has been confirmed that Lrg1 increases in cases of liver fibrosis, indicating that Lrg1 can be utilized for the diagnosis of liver diseases, including liver fibrosis. Furthermore, the potential of Lrg1 as a therapeutic target for liver diseases has been identified, allowing its use in the prevention or treatment of liver diseases.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques

Abrégé

Dillenia indicaDillenia indica L. extract as an active ingredient. The skin improvement composition comprising a Dillenia indica L. extract as an active ingredient according to the present invention has excellent antioxidant effects, autophagy activity increasing effects, and melanin production inhibitory effects. Accordingly, the Dillenia indica L. extract according to the present invention can be useful as a cosmetic composition for skin improvement or a functional health food composition.

Classes IPC  ?

• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61K 8/63 - StéroïdesLeurs dérivés
• A61Q 19/00 - Préparations pour les soins de la peau
• A61Q 19/08 - Préparations contre le vieillissement
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement
• A61Q 17/04 - Préparations topiques pour faire écran au soleil ou aux radiationsPréparations topiques pour bronzer
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés

Abrégé

The present invention relates to a biomarker composition for diagnosing liver disease. When RUNX3 was knocked out specifically in liver sinusoidal endothelial cells and vascular endothelial cells, an increase of the inflammatory cytokines IL-6, MCP-1, TNFa, and the like was confirmed, and an increase of angiogenesis and dysfunction of vascular endothelial cells in the liver were confirmed, and thus RUNX3 may be used for the prevention or treatment of hepatitis and liver disease.

Classes IPC  ?

• A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique

Abrégé

Disclosed is use of an antibody or antigen-binding fragment thereof that specifically binds to an acid sphingomyelinase (ASM) protein, wherein the antibody or antigen-binding fragment thereof specifically binds to an ASM protein with high binding affinity, significantly inhibits the activity of an ASM protein present in the cellular membrane, and shows effects of improving cognitive memory, inhibiting ASM protein activity, inhibiting the accumulation of amyloid-β and tau proteins, and inhibiting the production of neuroinflammation even without toxicity in Alzheimer's disease animal models, and thus can be advantageously used in the treatment of a brain disease.

Classes IPC  ?

• C07K 16/40 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre des enzymes
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

There are provided a multifunctional epoxy compound obtained by modifying two or more epoxide functional groups on terminal portions of liquid crystal molecules synthesized by bonding multiple thermotropic liquid crystal materials; and a cured product produced by reacting the compound with a curing agent. The compound and the cured product enable easy interaction between liquid crystals and exhibiting high thermal conductivity. They are usable alone as a heat-dissipating polymer, or in the form of a composite material, and are applicable as a matrix resin of a composite material.

Classes IPC  ?

• C08G 59/22 - Composés diépoxydés
• C07D 303/18 - Composés contenant des cycles oxirane avec des radicaux hydrocarbonés, substitués par des atomes d'oxygène liés par des liaisons simples ou doubles par des radicaux hydroxyle éthérifiés
• C07D 407/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C08G 59/50 - Amines
• C08L 63/00 - Compositions contenant des résines époxyCompositions contenant des dérivés des résines époxy

Abrégé

An artificial intelligence model system for predicting solar power generation on the basis of multiple data according to the present invention comprises: an input module that receives an input of numerical data including power generation amount information and weather information and a satellite image of a region where a solar power station is installed; a controller that configures a target area and a peripheral area in a cloud satellite image and a dust satellite image included in the satellite image; an image processing module that synthesizes the target area and the peripheral area and performs image deep learning to learn spatial information, and performs deep learning by using a CNN-LSTM combined neural network to learn spatiotemporal information; a numerical weather prediction module that performs deep leaning of the numerical data by using an LSTM neural network to learn temporal information; and an artificial intelligence model that performs deep learning by using result data of deep learning and predicts the power generation amount of the solar power station.

Classes IPC  ?

• H02S 50/00 - Surveillance ou tests de systèmes PV, p. ex. équilibrage de charge ou identification des défauts
• G06N 3/0464 - Réseaux convolutifs [CNN, ConvNet]
• G06N 3/0442 - Réseaux récurrents, p. ex. réseaux de Hopfield caractérisés par la présence de mémoire ou de portes, p. ex. mémoire longue à court terme [LSTM] ou unités récurrentes à porte [GRU]
• G06N 3/045 - Combinaisons de réseaux
• G06N 3/0455 - Réseaux auto-encodeursRéseaux encodeurs-décodeurs
• G06N 3/08 - Méthodes d'apprentissage
• G06T 9/00 - Codage d'image
• G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction

Abrégé

Disclosed is an apparatus for continuous spinning of coagulative polymeric microfibers comprising an outer microcatheter, an inner microcatheter having a smaller diameter than the outer microcatheter and inserted inside the outer microcatheter, a double lumen part in which the outer microcatheter and the inner microcatheter are coaxially superimposed with a radially spaced interstitial space, and a single lumen part formed by the outer microcatheter from an end of the inner microcatheter to an end of the outer microcatheter. A core fluid supplied through an interior of the inner microcatheter comprises a coagulative polymeric fluid, and a sheath fluid supplied through the interstitial space comprises a fluid including saline, wherein the core fluid and the sheath fluid may be configured to flow coaxially in the single lumen part to generate and discharge a coagulative polymeric microfiber.

Classes IPC  ?

• D01D 5/28 - Formation des filaments, fils ou similaires avec mélange des différentes solutions ou masses de filage au cours du filageEnsembles de filage à cet effet
• A61L 24/04 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
• A61M 25/00 - CathétersSondes creuses
• D01D 4/02 - Filières
• D01D 5/06 - Méthodes de filage au mouillé

Abrégé

The present invention relates to a composition for preventing, alleviating or treating sarcopenia, containing a low-molecular-weight collagen as an active ingredient, and the low-molecular-weight collagen of the present invention inhibits muscle protein breakdown and can exhibit a muscle-strengthening effect through an increase in muscle mass, and thus is expected to be effectively usable for preventing, alleviating or treating sarcopenia.

Classes IPC  ?

• A61K 38/39 - Peptides du tissu connectif, p. ex. collagène, élastine, laminine, fibronectine, vitronectine, globuline insoluble à froid [CIG]
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire

Abrégé

Disclosed are a high electron mobility transistor and a method for manufacturing the high electron mobility transistor. The high electron mobility transistor may comprise: a buffer layer; a channel layer formed on the buffer layer; an interlayer formed on the channel layer; a barrier layer formed on the interlayer; a source electrode formed in contact with the barrier layer; a drain electrode formed in contact with the barrier layer and spaced apart from the source electrode; a single crystal layer formed, between the source electrode and the drain electrode, on the barrier layer; and a gate electrode formed on the single crystal layer.

Classes IPC  ?

• H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
• H01L 29/66 - Types de dispositifs semi-conducteurs
• H01L 29/20 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIIBV

Abrégé

There are provided a compound having a thermotropic liquid crystalline structure and a polyethylene glycol polymer. The compound is obtained by modifying an epoxide functional group in a thermotropic liquid crystalline molecule. The polyethylene glycol polymer is obtained by ring-opening polymerization thereof. The polyethylene glycol main chain polymer is easy to form in thin film, bulk, or fiber form, and has a high thermal conductivity and thus can be used alone or in the form of a composite material as a heat-dissipating polymer.

Classes IPC  ?

• C09K 19/12 - Composés non stéroïdes formant des cristaux liquides contenant au moins deux cycles non condensés contenant au moins deux cycles benzéniques au moins deux cycles benzéniques directement liés, p. ex. biphényles
• C08G 65/26 - Composés macromoléculaires obtenus par des réactions créant une liaison éther dans la chaîne principale de la macromolécule à partir d'éthers cycliques par ouverture d'un hétérocycle à partir d'éthers cycliques et d'autres composés
• C09K 19/20 - Composés non stéroïdes formant des cristaux liquides contenant au moins deux cycles non condensés contenant au moins deux cycles benzéniques liés par une chaîne contenant des atomes de carbone et d'oxygène comme chaînons, p. ex. esters
• C09K 19/34 - Composés non stéroïdes formant des cristaux liquides contenant au moins un hétérocycle

Abrégé

The present invention relates to a technical idea of three-dimensional quantitative magnetic resonance imaging for precisely measuring cerebral oxygen metabolism and, more particularly, to a technology for quantitative magnetic resonance imaging which enables measurement of cerebral oxygen metabolism to be precisely performed in three dimensions throughout the entire brain region by using multi-echo ultrashort echo-time (UTE)-alternating unbalanced SSFP-FID & SSFP-ECHO (AUSFIDE) image data, a plurality of pieces of measurement data to be pre-processed, and separately acquired cerebral blood volume information data. The magnetic resonance imaging device according to one embodiment of the present invention may comprise: a data acquisition unit configured to acquire ultrashort echo-time (UTE)-alternating unbalanced SSFP-FID & SSFP-ECHO (AUSFIDE) image data, velocity-selective venous spin labeling (VS-VSL) image data, and pseudo-continuous arterial spin labeling (pCASL) image data; a data preprocessing unit configured to process a plurality of pieces of preliminary information data for quantitative model processing, on the basis of the acquired ultrashort echo-time (UTE)-alternating unbalanced SSFP-FID & SSFP-ECHO (AUSFIDE) image data and the acquired velocity-selective venous spin labeling (VS-VSL) image data, and to process cerebral blood flow (CBF) information data on the basis of the acquired pseudo-continuous arterial spin labeling (pCASL) image data; a quantitative model processing unit configured to acquire variable information (Yv) for inducing oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) in order to acquire a three-dimensional oxygen metabolic rate map for the entire brain by using the plurality of pieces of processed preliminary information data; and an image generation unit configured to induce the oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO2) by using the acquired variable information to generate a magnetic resonance image from the oxygen metabolic rate map image.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
• G01R 33/56 - Amélioration ou correction de l'image, p. ex. par des techniques de soustraction ou d'établissement de moyenne

Abrégé

The present invention relates to a composition for single-cell proteomics analysis, a sample treatment method using same, and a method for unifying the labeling of ultra-small amounts of peptides. Particularly, the present invention relates to: a sample pretreatment composition for quantitative protein analysis, the sample pretreatment composition comprising a sulfobetaine-based amphoteric surfactant and N,N,N',N-tetrakis(2-hydroxypropyl)ethylenediamine as active ingredients; a sample pretreatment tube for quantitative protein analysis using the sample pretreatment composition, in which a centrifugal separation tube is equipped with a thin film having a plurality of micro through-holes; and a method for unifying and preparing a sample for quantitative protein analysis, the method comprising the steps of injecting a biological sample into micro through-holes provided in the sample pretreatment tube for quantitative protein analysis according to the present invention, treating the micro through-holes with the sample pretreatment composition for quantitative protein analysis, the sample pretreatment composition comprising a sulfobetaine-based amphoteric surfactant and N,N,N',N-tetrakis(2-hydroxypropyl)ethylenediamine as active ingredients, and allowing a reaction to occur, and when the reaction is completed, centrifuging the sample pretreatment tube in a centrifuge to obtain a pretreated sample collected at the bottom of the tube.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• G01N 30/72 - Spectromètres de masse
• G01N 1/28 - Préparation d'échantillons pour l'analyse

Abrégé

The present invention relates to use of an odorant receptor for suppressing the lactate-induced M2-type differentiation of tumor-associated macrophages and tumor growth. In particular, the inventors of the present invention assumed that lactate-activated OR Olfr78 would function as a macrophage lactate sensor, and confirmed whether Olfr78 on bone marrow-derived macrophages (BMDMs) detect tumor-derived lactate and lactate-induced M2 polarization. The inventors of the present invention attempted to identify factors detected by Olfr78 in tumor conditioned media (TCM), and discovered that lactate in TCM and acetic acid under some conditions are major factors involved in Olfr78-mediated generation of tumor-friendly M2-TAMs. Finally, it was found that Olfr78 deficiency inhibited tumor progression and metastasis and improved antitumor immunity in vivo (in vivo). According to the present invention, Olfr78-lactate interaction plays a major role in tumor progression, and thus, targeting of the Olfr78-lactate axis can be effectively used in targeted cancer therapy.

Classes IPC  ?

• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens

Abrégé

The present invention relates to a benzimidazolylurea derivative and a pharmaceutical use thereof. The benzimidazolylurea derivative exhibits excellent effects in treating and preventing pathological symptoms caused by excessive glucocorticoids by inhibiting adrenal corticosteroid production and cholesterol biosynthesis and can be used for the prevention and treatment of endogenous hypercortisolism.

Classes IPC  ?

• C07D 235/30 - Atomes d'azote ne faisant pas partie d'un radical nitro
• A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
• A61P 5/38 - Médicaments pour le traitement des troubles du système endocrinien des hormones surrénales
• A61P 43/00 - Médicaments pour des utilisations spécifiques, non prévus dans les groupes
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs

Abrégé

The present invention relates to a contaminated groundwater treatment method using Capsosiphon fulvescens-based biochar, the method treating contaminated materials through the activation of persulfate by using Capsosiphon fulvescens-based biochar as a catalyst.

Classes IPC  ?

• C02F 1/28 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par absorption ou adsorption
• B01J 21/18 - Carbone
• C02F 101/30 - Composés organiques
• C02F 101/10 - Composés inorganiques

Abrégé

The present invention relates to a composition for inhibiting skin pigmentation through enhanced autophagy activity, comprising procyanidin A2 and quercetin as active ingredients. The combination of procyanidin A2 and quercetin compounds not only inhibits tyrosinase but also increases autophagy activity, thus showing remarkable effectiveness in inhibiting melanin synthesis. Therefore, this composition can be advantageously used in various materials, including food products, cosmetic compositions, and pharmaceutical compositions, associated with skin pigmentation.

Classes IPC  ?

• A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
• A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement

Abrégé

The present invention relates to a composition for bone regeneration, comprising: a biodegradable synthetic polymer; a biocompatible polymer compound including catechol groups; a collagen; and a bioactive substance, and provides a bone-regeneration scaffold including the composition for bone regeneration.

Classes IPC  ?

• A61L 27/26 - Mélanges de matériaux macromoléculaires
• A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
• A61L 27/24 - Collagène
• A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
• A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
• A61L 27/56 - Matériaux poreux ou cellulaires
• C08B 37/08 - ChitineSulfate de chondroïtineAcide hyaluroniqueLeurs dérivés
• C08L 5/08 - ChitineSulfate de chondroïtineAcide hyaluroniqueLeurs dérivés
• C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p. ex. lactones
• C08L 89/00 - Compositions contenant des protéinesCompositions contenant leurs dérivés

Abrégé

The present invention relates to a rotational joint device for driving a wearable robot cable, the device being improved such that only one motor is used to bidirectionally drive a joint cable and torque can be amplified through repeated routing applied to a rolling joint. The present invention provides the rotational joint device for driving a wearable robot cable, comprising: a base; a joint part provided at the base; a link member provided to be linked to the joint part; a driving cable of which one side is connected to the link member so that the link member is driven; and a cable driving part to which the other side of the driving cable is connected so that the driving cable is driven, thereby allowing the link member to be driven.

Classes IPC  ?

• B25J 9/10 - Manipulateurs à commande programmée caractérisés par des moyens pour régler la position des éléments manipulateurs
• B25J 9/00 - Manipulateurs à commande programmée

Abrégé

The present invention relates to a docking method by which an unmanned moving body located in a mission area moves to a docking area to be docked, the method including the steps in which: a docking station located in the docking area measures a signal transmitted or received through wireless communication with the unmanned moving body and calculates a measurement value; the unmanned moving body generates a docking path on the basis of the measurement value; and the unmanned moving body is docked to the docking station on the basis of the docking path. As such, docking of the unmanned moving body to the docking station can be possible using low power and low cost while being less affected by the environment.

Classes IPC  ?

• G05D 1/20 - Entrées des système de commande
• G01S 11/06 - Systèmes pour déterminer la distance ou la vitesse sans utiliser la réflexion ou la reradiation utilisant les ondes radioélectriques utilisant des mesures d'intensité
• G01S 11/02 - Systèmes pour déterminer la distance ou la vitesse sans utiliser la réflexion ou la reradiation utilisant les ondes radioélectriques

Abrégé

Disclosed are a person distinguishing apparatus using a photoplethysmography (PPG) signal, and a method therefor, the apparatus using a PPG signal mainly used for pulse or blood oxygen saturation measurement or the like in daily life, so as to distinguish a person. The person distinguishing apparatus using a PPG signal comprises: a recurrence plot conversion unit using a wearable device so as to convert, into a recurrence plot (RP), a PPG signal measured during daily life; and a deep learning processing unit training a 2D convolutional neural network (CNN) model with an image converted into the RP, so as to make an inference about a person. Therefore, a method for utilizing daily-life biometric data including various noises and situations is provided, and thus, during telemedicine, data can be collected and analyzed and, simultaneously, a person can be distinguished.

Classes IPC  ?

• G16H 50/00 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
• G06N 3/0464 - Réseaux convolutifs [CNN, ConvNet]

Abrégé

A crane system for fall prevention and position following of an object to be moved, according to the present invention, may comprise: a top support frame horizontally positioned above the top of an object to be moved; a tilt sensor attached to the object to be moved, so as to sense the tilt of the object to be moved; a towing connection member for connecting the top support frame and the object to be moved; a towing motor, which pulls the towing connection member so as to upwardly tow the object to be moved; and a control device, which drives the towing motor so as to upwardly tow, to a first predetermined height, the object to be moved, if the tilt of the object to be moved, detected through the tilt sensor, is a predetermined angle or greater.

Classes IPC  ?

• B66C 13/48 - Commande automatique de l'entraînement des grues pour produire un cycle de travail unique ou répétéCommande par programmation
• B66C 13/46 - Indicateurs de position pour charges suspendues ou pour éléments de grues
• B66C 15/00 - Mécanismes de sécurité

Abrégé

The present invention relates to a composition for preventing, treating or alleviating fatty liver or obesity, comprising an extract of Crataegus pinnatifida Bunge roots. The present inventors identified that the extract of Crataegus pinnatifida Bunge roots effectively inhibits preadipocyte cell differentiation without cytotoxicity, reduces lipid accumulation in adipocytes, and inhibits the expression of a transcription factor or adiponectin, which is involved in the formation and differentiation of adipocytes. In addition, an adiposis inhibitory effect and the effect of alleviating liver damage caused by high-fat feeding has been identified in high-fat diet mice, and it has been identified that adipogenesis and lipid accumulation are inhibited in high-fat diet mice. Therefore, Crataegus pinnatifida Bunge roots of the present invention can be effectively used as a pharmaceutical composition, a health functional food and the like for preventing, treating or alleviating fatty liver of obesity.

Classes IPC  ?

• A61K 36/734 - Crataegus (aubépine)
• A61P 3/04 - AnorexigènesMédicaments de l'obésité
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
• A61K 8/9789 - Magnoliopsida [dicotylédones]
• A61Q 19/00 - Préparations pour les soins de la peau
• A61Q 19/06 - Préparations pour lutter contre la cellulite
• A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques

Abrégé

The present invention provides a desalination combined catalyst electrode device, which is an electrolyzer composed of anode cell/BPM/[AEM/CEM]n/BPM/cathode cell, wherein: the anode cell contains a Ni/3d transition metal composite catalyst electrode while the fraction of 3d transition metal in the electrode is 0.3 or less; n is a natural number of 1 to 5 and AEM and CEM are located alternately; and the electrolyzer has a 50% desalination time (τ1/2) of 2.2 to 6.4 hours and a specific energy consumption (SEC) of 1.79 to 7.03 kWhm-3at J = 10 mA/cm-2.　The present invention also provides a method for manufacturing a nickel transition metal composite catalyst electrode by utilizing single-step electrodeposition, the method comprising the steps of: forming a mixture solution of hydrates containing Ni and a 3d transition metal at a ratio of 1:3 to 3:1; immersing a Ni substrate in the solution, followed by cathode bias electrodeposition for 10 to 180 seconds; and anodizing, washing, and drying the electrodeposited Ni/3d transition metal double hydrate composite catalyst electrode.

Classes IPC  ?

• C02F 1/461 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse
• C02F 1/46 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques
• C02F 1/467 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse par désinfection électrochimique

Abrégé

Disclosed are an augmented reality clinical simulation system and method for emergency response training. An augmented reality clinical simulation system for emergency response training according to one aspect of the present invention comprises: a patient device for training in which a patient condition is set; one or more trainee devices which are worn by trainees and output treatment guide information according to the patient condition in augmented reality; one or more medical support devices; and a central control device which sets the patient condition and provides the trainee devices with the treatment guide information, and which identifies the medical support devices and enables medical information or virtual medical equipment to be checked in augmented reality using the trainee devices so as to correspond to the medical support devices.

Classes IPC  ?

• G09B 9/00 - Simulateurs pour l'enseignement ou l'entraînement
• G09B 7/02 - Dispositifs ou appareils d'enseignement à commande électrique procédant par questions et réponses du type où l'élève doit donner une réponse à la question posée, ou bien où la machine donne une réponse à la question posée par l'élève
• G06Q 50/20 - Éducation
• G06Q 50/10 - Services
• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
• G02B 27/01 - Dispositifs d'affichage "tête haute"

Abrégé

A foveated near-eye display having multiple focal planes may comprise: an image-providing element that outputs a laser beam; a variable focus lens (varifocal lens) through which the laser beam is transmitted; a scanning mirror that reflects the laser beam transmitted through the variable focus lens; a main lens positioned between a user's eye and the scanning mirror; and a control unit that adjusts the angle of the scanning mirror so that the laser beam is scanned toward the main lens.

Classes IPC  ?

• G02B 27/01 - Dispositifs d'affichage "tête haute"

Abrégé

Ldd Ldd Ldd Ldd ααδδ δδ Ldd αLdd Ldd d , thereby improving the vehicle's driving stability and the reference path tracking performance.

Classes IPC  ?

• G05D 1/20 - Entrées des système de commande
• G05D 1/00 - Commande de la position, du cap, de l'altitude ou de l'attitude des véhicules terrestres, aquatiques, aériens ou spatiaux, p. ex. utilisant des pilotes automatiques
• B25J 9/16 - Commandes à programme
• B60W 40/02 - Calcul ou estimation des paramètres de fonctionnement pour les systèmes d'aide à la conduite de véhicules routiers qui ne sont pas liés à la commande d'un sous-ensemble particulier liés aux conditions ambiantes

Abrégé

The present invention relates to a novel peptide having the effect of treating neuroinflammatory diseases, and a use thereof, and more specifically, to a novel peptide having an Lipocalin-2 (LCN2) inhibitory activity which is closely related to neuroinflammation, and a composition for preventing or treating neuroinflammatory diseases, the composition comprising the peptide.

Classes IPC  ?

• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux

Abrégé

Disclosed are an extended reality clinical simulation system and method for medical practice. The extended reality clinical simulation system for medical practice, according to an aspect of the present invention, comprises: a patient device for practice in which conditions of a patient are set; practitioner devices that are worn by a plurality of practitioners and output, in augmented reality, treatment guide information according to the conditions of the patient; and a central control device that sets the conditions of the patient and provides the treatment guide information to each of the practitioner devices according to a role of each practitioner.

Classes IPC  ?

• G09B 9/00 - Simulateurs pour l'enseignement ou l'entraînement
• G09B 5/02 - Matériel à but éducatif à commande électrique avec présentation visuelle du sujet à étudier, p. ex. en utilisant une bande filmée
• G09B 23/30 - Modèles anatomiques
• G06Q 50/20 - Éducation
• G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
• G06F 3/048 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI]
• G02B 27/01 - Dispositifs d'affichage "tête haute"
• G09B 5/06 - Matériel à but éducatif à commande électrique avec présentation à la fois visuelle et sonore du sujet à étudier
• G06Q 50/10 - Services
• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération

Abrégé

The present invention relates to an optical neural network device through clustered opto-electronic modules, the device having an opto-electronic module clustering structure in which N opto-electronic modules having M input terminals and M output terminals are arranged in parallel with the input terminals and the output terminals aligned in the same direction to form a (2P-1)th stack, and N+1 opto-electronic modules having M input terminals and M output terminals are arranged in parallel with the input terminals and the output terminals aligned in the same direction to form a (2P)th stack, wherein the output terminals of the opto-electronic modules forming the (2P-1)th stack are connected to the input terminals of the opto-electronic modules forming the (2P)th stack, the opto-electronic module clustering structure has (M/2)*N inputs with a left-right symmetrical structure and (M/2)*N outputs with a left-right symmetrical structure, and the opto-electronic modules in each stack transmit, to the output terminal, an optical signal input through the input terminal, and perform any one of transmission processes among transmissions after branching or copying or straight connection, cross connection or full connection and weight calculation.

Classes IPC  ?

• G06N 3/067 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens optiques

Abrégé

The present disclosure relates to a composition for skin whitening containing a Nypa fruticans extract as an active ingredient. The composition has an effect of reducing melanin content and inhibiting melanogenesis, and enhances a skin whitening effect by enhancing autophagy activity, and thus can be used in a cosmetic composition, a health functional food composition, and a pharmaceutical composition.

Classes IPC  ?

• A61K 8/9794 - Liliopsida [monocotylédones]
• A61K 36/889 - Arecaceae, Palmae ou Palmaceae (famille du palmier), p. ex. dattier ou cocotier ou palmier nain
• A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
• A61Q 19/02 - Préparations pour les soins de la peau pour décolorer ou blanchir la peau chimiquement

Abrégé

The present invention relates to an electrical stimulation system for improving vertebral synostosis, comprising: a spinal cage formed of a porous structure having closed front and rear surfaces and inserted between the vertebrae of a user to deliver electrical stimulation to the user; and a power supply device for transmitting wireless power to generate electrical stimulation in the spinal cage, the power supply device having a form wearable by the user. Through the system, the user's vertebral synostosis can be improved.

Classes IPC  ?

• A61N 1/32 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents
• A61N 1/378 - Alimentation en courant électrique
• A61N 1/375 - Aménagements structurels, p. ex. boîtiers
• A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
• A61N 1/05 - Électrodes à implanter ou à introduire dans le corps, p. ex. électrode cardiaque
• H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
• A61F 2/44 - Articulations pour l'épine dorsale, p. ex. vertèbres, disques intervertébraux

Abrégé

The present invention relates to a composition including catechin hydrate as an active ingredient for the prevention, alleviation, or treatment of chronic obstructive pulmonary disease. The catechin hydrate of the present invention significantly inhibits fine dust-induced cell apoptosis in human bronchial epithelial cells, restores mitochondrial function, and suppresses lung damage, and thus can be effectively used in a composition for the prevention, alleviation, or treatment of chronic obstructive pulmonary diseases such as emphysema, chronic bronchitis, asthma, or pneumonia.

Classes IPC  ?

• A61K 36/65 - Paeoniaceae (famille de la pivoine), p. ex. pivoine chinoise
• A61K 31/353 - 3,4-Dihydrobenzopyranes, p. ex. chromane, catéchine
• A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés

Abrégé

Provided are a method and device for estimating the GPS coordinates of multiple target objects and tracking the target objects on the basis of camera image information from an unmanned aerial vehicle according to an embodiment. The device comprises: a detection unit that, through a pre-trained artificial intelligence deep learning model, detects an object corresponding to an assignment set in the unmanned aerial vehicle, and generates a bounding box including the detected target object according to the size of the target object; a setting unit that sets a reference pixel that is a target point represented as a pixel on a camera image plane; a calculation unit that calculates reference pixel coordinates of the target object in a two-dimensional pixel coordinate system; and a conversion unit that converts the reference pixel coordinates of the target object into three-dimensional coordinates by using at least one of altitude information about the unmanned aerial vehicle or depth information about the target object, and converts the coordinate system of the converted three-dimensional coordinates to acquire the GPS coordinates of the target object.

Classes IPC  ?

• G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
• G06T 7/55 - Récupération de la profondeur ou de la forme à partir de plusieurs images
• G06T 3/00 - Transformations géométriques de l'image dans le plan de l'image
• G06N 3/08 - Méthodes d'apprentissage
• G05D 1/00 - Commande de la position, du cap, de l'altitude ou de l'attitude des véhicules terrestres, aquatiques, aériens ou spatiaux, p. ex. utilisant des pilotes automatiques
• G05D 1/20 - Entrées des système de commande
• B64C 39/02 - Aéronefs non prévus ailleurs caractérisés par un emploi spécial

Abrégé

The present invention relates to a composition for preventing, alleviating or treating sarcopenia, containing D-ribo-2-hexulose as an active ingredient. D-ribo-2-hexulose of the present invention is a sweetener capable of replacing sugar, is harmless to the human body and does not cause side effects in normal cells so as to be safe for the human body, inhibits the degradation of myoproteins, and can exhibit muscle strengthening effects by increasing muscle mass, and thus the present invention is expected to be effectively usable in the prevention, alleviation or treatment of sarcopenia.

Classes IPC  ?

• A61K 31/047 - Composés hydroxylés, p. ex. alcoolsLeurs sels, p. ex. alcoolates ayant plusieurs groupes hydroxyle, p. ex. sorbitol
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire

Abrégé

The present invention relates to a composition for improving bone function comprising sericin, and use thereof. The sericin of the present invention is a protein derived from a natural material, and thus not only is safe, has less denaturation, and is biocompatible, but is also excellent for improving bone function. In particular, a drink-type health functional food for improving bone function comprising the sericin of the present invention as an active ingredient solves the inconvenience of treatment methods compared to existing injectable or tablet therapeutic agents as preparations for improving bone function and curing bone disease damage, and can not only be a great alternative to the existing injectable or tablet therapeutic agents, but also can contribute to economic growth and social benefits by recycling sericin that is discarded as a by-product of silk protein.

Classes IPC  ?

• A23L 33/17 - Acides aminés, peptides ou protéines
• A23L 2/38 - Autres boissons non alcoolisées
• A23K 10/20 - Produits alimentaires pour animaux à base de matières d’origine animale
• A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
• A61K 35/64 - Insectes, p. ex. abeilles, guêpes ou puces
• A61P 19/08 - Médicaments pour le traitement des troubles du squelette des maladies osseuses, p. ex. rachitisme, maladie de Paget
• C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires

Abrégé

A system for diagnosing a machine failure according to an embodiment of the inventive concept includes a pre-processing module that receives a primitive signal in a time-amplitude domain to generate a Mel spectrum image in a time-frequency domain, a feature extraction module that learns features of the Mel spectrum image to output an Euclidean distance between a latent variable and a centroid, a failure diagnosis module that performs classification into a preset number of classes on the basis of the Euclidean distance between the latent variable and the centroid, and a result output module that outputs whether a failure has occurred according to a class classified by the failure diagnosis module.

Classes IPC  ?

• G01M 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
• G05B 23/02 - Test ou contrôle électrique

Abrégé

The present invention relates to a method for forming a three-dimensional structure by using UV parallel light in a multilayered stacked structure, and a three-dimensional structure formed by the method, and, specifically, to: a method, which emits parallel light and UV light at a photomask so as to use UV parallel light in an improved multilayered stacked structure having the effects of impact resistance, resilience, elongation, and low-reflective coating, thereby forming a three-dimensional structure; a three-dimensional structure formed by the method; and an element employing the three-dimensional structure. The three-dimensional structure according to a manufacturing method of the present invention comprises an impact-absorption layer skeleton support and an impact cushioning part in the vicinity of the skeleton support that each have a different modulus value. The skeleton support maintains high hardness of the structure and the impact cushioning part distributes internal/external impact, and thus a three-dimensionally shaped impact-absorption layer having excellent impact resistance, resilience, and elongation can be manufactured. The impact-absorption layer can also be used in a stacked structure and an element that employs the stacked structure.

Classes IPC  ?

• H10K 77/10 - Substrats, p. ex. substrats flexibles
• H10K 71/00 - Fabrication ou traitement spécialement adaptés aux dispositifs organiques couverts par la présente sous-classe
• G09F 9/30 - Dispositifs d'affichage d'information variable, dans lesquels l'information est formée sur un support, par sélection ou combinaison d'éléments individuels dans lesquels le ou les caractères désirés sont formés par une combinaison d'éléments individuels
• H10K 102/00 - Détails de structure relatifs aux dispositifs organiques couverts par la présente sous-classe

Abrégé

The present invention pertains to a novel compound derivative and a pharmacological use thereof and specifically to a novel 1,1-dioxo-1,2-benzisothiazole derivative or novel 3-citryl-1H-pyrazole derivatives possessing antiplatelet activity, and a pharmaceutical use thereof. The 1,1-dioxo-1,2-benzisothiazole derivative or 5-amino-3-(1-cyano-2-(3,4,5-trimethoxyphenyl)vinyl)-1H-pyrazole-4-carbonitrile according to the present invention can suppress the activation of glycoprotein (GP) IIb/IIIa to inhibit platelet aggregation, thereby demonstrating potential prophylactic, ameliorative, or therapeutic effects against thrombotic diseases and cardiovascular disorders.

Classes IPC  ?

• A61K 31/415 - 1,2-Diazoles
• A61P 7/02 - Agents antithrombotiquesAnticoagulantsAnti-agrégants plaquettaires
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• C07D 275/06 - Composés hétérocycliques contenant des cycles thiazole-1, 2 ou thiazole-1, 2 hydrogéné condensés avec des carbocycles ou avec des systèmes carbocycliques avec des hétéro-atomes liés directement à l'atome de soufre du cycle
• A61K 31/428 - Thiazoles condensés avec des carbocycles
• A61K 31/497 - Pyrazines non condensées contenant d'autres hétérocycles

Abrégé

The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a COX2 acetylating agent as an active ingredient and, more particularly, to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising, as an active ingredient, a COX2 acetylating agent which exhibits an effect of inhibiting the deposition of amyloid-β in brain neurons, reducing excessive neuroinflammatory responses, and increasing the phagocytosis of amyloid-β in microglial cells. The pharmaceutical composition for preventing or treating neurodegenerative diseases comprising the COX2 acetylating agent as an active ingredient has the effects of alleviating neuroinflammation by promoting COX2 acetylation in neurons and secreting specialized pro-resolving mediators (SPMs) and thus, can be very useful in the development of a preventive or therapeutic agent for neurodegenerative diseases.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
• A61K 31/164 - Amides, p. ex. acides hydroxamiques d'un acide carboxylique avec un aminoalcool, p. ex. céramides
• G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
• G01N 33/573 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour enzymes ou isoenzymes

Abrégé

Proposed are a complex catalyst containing an imine-based ligand for polymerizing a cyclic olefin-based monomer and a method of preparing a cyclic olefin-based polymer using the same. More particularly, proposed are a complex catalyst containing an imine-based ligand for polymerizing a cyclic olefin-based monomer, which can provide the complex catalyst containing the imine-base ligand having high activity in polymerizing the cyclic olefin-based monomer and can prepare a cyclic olefin-based polymer with high activity by polymerizing the cyclic olefin-based monomer in the presence of the complex catalyst containing the imine-based ligand, and a method of preparing a cyclic olefin-based polymer using the same.

Classes IPC  ?

• C08F 32/08 - Homopolymères ou copolymères de composés cycliques ne contenant pas de radicaux aliphatiques non saturés dans une chaîne latérale et contenant une ou plusieurs liaisons doubles carbone-carbone dans un système carbocyclique contenant des cycles condensés
• C08F 2/06 - Solvant organique
• C08F 4/70 - Métaux du groupe du fer, métaux du groupe du platine ou leurs composés

Abrégé

A method for manufacturing an eco-friendly capsule includes: disposing a water phase material containing chitosan at a first site, and disposing an oil phase material at a second site and a third site, on a microfluidic chip; moving the water phase material and the oil phase material to a reaction site according to a predetermined flow ratio to produce an emulsion containing droplets having a predetermined diameter; mixing the emulsion with a water phase solution in a mixing tank; and producing chitosan beads by the reaction of the emulsion with the water phase solution.

Classes IPC  ?

• A01N 25/28 - Microcapsules
• A01N 25/10 - Composés macromoléculaires
• A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
• B01J 13/18 - Polymérisation in situ où tous les réactifs sont présents dans la même phase
• B01J 13/20 - Post-traitement des parois des capsules, p. ex. durcissement

Abrégé

A voice recognition device of the present invention may comprise: a first pre-learning unit, which uses a first artificial intelligence model so as to extract a first feature expression from learning voice data; a second pre-learning unit, which uses a second artificial intelligence model so as to extract a second feature expression from the first feature expression; and a voice recognition unit, which uses a third artificial intelligence model so as to extract predictive text from the second feature expression.

Classes IPC  ?

• G10L 15/26 - Systèmes de synthèse de texte à partir de la parole
• G10L 15/06 - Création de gabarits de référenceEntraînement des systèmes de reconnaissance de la parole, p. ex. adaptation aux caractéristiques de la voix du locuteur
• G10L 15/02 - Extraction de caractéristiques pour la reconnaissance de la paroleSélection d'unités de reconnaissance
• G10L 15/16 - Classement ou recherche de la parole utilisant des réseaux neuronaux artificiels
• G10L 25/18 - Techniques d'analyse de la parole ou de la voix qui ne se limitent pas à un seul des groupes caractérisées par le type de paramètres extraits les paramètres extraits étant l’information spectrale de chaque sous-bande
• G10L 15/183 - Classement ou recherche de la parole utilisant une modélisation du langage naturel selon les contextes, p. ex. modèles de langage
• G06N 20/00 - Apprentissage automatique

Abrégé

The present invention relates to a composition for treating a cancer disease, comprising an extracellular vesicle derived from natural killer cells with surface expression of cytokine and an antibody. By expressing IL-15 and a cancer cell-specific antibody on the surface of human natural killer cells, it is possible to provide an extracellular vesicle that can exhibit strong cytotoxic activity specifically against cancer cells. The extracellular vesicle can be provided as a new anticancer agent that is safe for the human body and exhibits an excellent anticancer effect. In addition, the extracellular vesicle of the present invention can be used to deliver drugs or bioactive substances to specific cancer cells by encapsulating the drugs or bioactive substances having a therapeutic effect on cancer therein, and thus can be provided as a new means of treating cancer.

Classes IPC  ?

• A61K 35/17 - LymphocytesLymphocytes BLymphocytes TCellules tueuses naturellesLymphocytes activés par un interféron ou une cytokine
• A61K 38/20 - Interleukines
• A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
• A61K 9/50 - Microcapsules
• A61P 35/00 - Agents anticancéreux
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps

Abrégé

The present invention relates to a screening method for a therapeutic agent for vascular calcification, in which it was confirmed that, in a CaBP9K-deletion model among vascular-calcification-induced animal models, vascular calcification was ameliorated, compared to a normal model, and thus the screening method is useful as a method for screening for a composition for the prevention, treatment, amelioration, or diagnosis of vascular calcification, or for a therapeutic agent for vascular calcification.

Classes IPC  ?

• G01N 33/483 - Analyse physique de matériau biologique
• G01N 33/558 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet utilisant la diffusion ou la migration de l'anticorps ou de l'antigène
• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• A61B 6/03 - Tomographie informatisée
• A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

Abrégé

The present invention relates to a polysubstituted imidazolo[4,5-c][1,2]thiazine derivative and a use of an agent comprising same as an active agent, which is useful for infectious diseases associated with vascular inflammation caused by HMGB1 protein activity. It has been found that the polysubstituted imidazolo[4,5-c][1,2]thiazine derivative of the present invention increases the sepsis survival rate as a result of searching for antiseptic effects through CLP-induced sepsis animal experiments. Accordingly, the agent comprising the polysubstituted imidazolo[4,5-c][1,2]thiazine derivative or a pharmaceutically acceptable salt thereof as an active agent may be advantageously used as a therapeutic agent for infectious diseases and vascular inflammatory diseases including sepsis caused by HMGB1 protein activity.

Classes IPC  ?

• C07D 513/04 - Systèmes condensés en ortho
• A61P 31/00 - Agents anti-infectieux, c.-à-d. antibiotiques, antiseptiques, chimiothérapeutiques