Abrégé

A method, device, computing equipment, and storage medium for predicting the drift of the floating object are provided. A method for predicting drift velocity includes: obtaining environmental characteristic parameters at the location of the floating object to be predicted, wherein the environmental characteristic parameters include wave characteristic parameters; inputting the wave characteristic parameters into a deep learning model for wave-induced drift velocity to obtain the wave-induced drift velocity; wherein the deep learning model for wave-induced drift velocity is trained based on first sample drift data, wherein the first sample drift data includes observed drift velocity of sample floating objects, corresponding sample water surface flow characteristic parameters, sample wind characteristic parameters, and sample wave characteristic parameters.

Classes IPC  ?

• G01S 15/58 - Systèmes de détermination de la trajectoire ou de la vitesseSystèmes de détermination du sens d'un mouvement
• G01C 13/00 - Géodésie spécialement adaptée à l'eau libre, p. ex. à la mer, aux lacs, aux rivières ou aux canaux
• G01S 7/52 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe

Abrégé

The subject invention pertains to hexacyclic xanthones isolated from marine bacteria. These chrexanthomycins are effective TRPV1 inhibitors that are effective as analgesics.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
• A61K 47/20 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant du soufre, p. ex. sulfoxyde de diméthyle [DMSO], docusate, laurylsulfate de sodium ou acides aminosulfoniques
• A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]

Abrégé

A process involves adding charged fibers with surface-cured “temperature-sensitive gel” during the preparation of concrete; preparing charged fibers with surface-cured “temperature-sensitive gel” by spraying, which envelops the charged fibers with a layer of “temperature-sensitive gel”; then solidifying the temperature-sensitive gel layer on the surface of the charged fibers by adjusting the environmental temperature. Utilizing the physical state of the temperature-sensitive gel at different temperatures, the “temperature-sensitive gel” wraps around the charged fibers to form an insulating layer. This prevents the scattering of the charged fibers due to charge repulsion during their introduction into the concrete preparation process, ensuring they are evenly distributed.

Classes IPC  ?

• C04B 20/10 - Revêtement ou imprégnation
• B05B 12/02 - Aménagements de commande de la distributionAménagements de réglage de l’aire de pulvérisation pour la commande de la durée ou de la succession des distributions
• B28C 5/40 - Appareillages ou procédés pour la production de mélanges de ciment avec d'autres substances, p. ex. coulis, mortiers, compositions poreuses ou fibreuses de mélange spécialement adaptés pour préparer des mélanges contenant des fibres
• C04B 14/04 - Matières riches en siliceSilicates
• C04B 14/06 - QuartzSable
• C04B 22/06 - OxydesHydroxydes
• C04B 28/08 - Ciments de scories
• C04B 40/00 - Procédés, en général, pour influencer ou modifier les propriétés des compositions pour mortiers, béton ou pierre artificielle, p. ex. leur aptitude à prendre ou à durcir
• D06M 15/03 - Polysaccharides ou leurs dérivés

Abrégé

Provided are a modified mu-conotoxin, a preparation method therefor, and a use thereof. Amino acid residue modification is performed on the basis of wild-type μ-conotoxin PIIIA, so that the blocking effect of μ-conotoxin on a sodium channel is moderately weakened, meanwhile, the stability is maintained under both acidic and alkaline conditions, and isoelectric point stability and target specificity are maintained. The provided modified mu-conotoxin has the characteristics such as stability and low production costs. The modified mu-conotoxin maintains a good anti-wrinkle function, and the modified mu-conotoxin can be used to prevent facial muscle stiffness and paralysis caused by excessive inhibition of skeletal muscle sodium channel Nav1.4; meanwhile, the risk of inhibiting a myocardial sodium channel and a brain sodium channel is remarkably reduced, and transmembrane absorption is facilitated.

Classes IPC  ?

• C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• C07K 1/04 - Procédés généraux de préparation de peptides sur des supports
• C07K 1/06 - Procédés généraux de préparation de peptides utilisant des groupes protecteurs ou des agents d'activation
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
• A61K 8/64 - ProtéinesPeptidesLeurs dérivés ou produits de dégradation
• A61Q 19/08 - Préparations contre le vieillissement
• A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
• A61P 21/02 - Relaxants musculaires, p. ex. pour la tétanie ou les crampes

Abrégé

Embodiments of the present invention relate to a drift prediction method and apparatus of a floating object, a computing device, and a storage medium. The embodiments of the present invention provide a drift speed prediction method, comprising: obtaining environment characteristic parameters of a position where a floating object to be predicted is located, the environment characteristic parameters comprising wave characteristic parameters; and inputting the wave characteristic parameters into a pre-trained wave-induced drift deep learning model to obtain a wave-induced drift speed, wherein the wave-induced drift deep learning model is obtained by training on the basis of first sample drift data, and the first sample drift data comprises a sample drift speed observation value of a sample floating object, a corresponding sample surface layer water flow characteristic parameter, a sample wind characteristic parameter and a sample wave characteristic parameter. By predicting the wave-induced drift speed, a drift speed of the floating object to be predicted can be predicted more accurately, and then a drift path of the floating object to be predicted can be predicted more accurately.

Classes IPC  ?

• G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle

Abrégé

The embodiments of the present disclosure relate to a wind-induced drift prediction method and apparatus, and a device and a storage medium. A drift prediction method for a floating object comprises: acquiring environmental parameters at the position where a floating object is located; according to the environmental parameters, determining a predicted drift deviation at the position where the floating object is located, wherein the predicted drift deviation is the deviation of a predicted wind-induced drift direction of the floating object relative to a wind direction; selecting a corresponding wind-induced drift coefficient according to the predicted drift deviation; and determining a wind-induced drift speed of the floating object according to the wind-induced drift coefficient. By using the drift prediction method for a floating object provided in the present solution, a drift deviation can be determined on the basis of environmental parameters, and a wind-induced drift speed is then calculated, instead of randomly determining a drift deviation and calculating a wind-induced drift speed in the prior art, such that the wind-induced drift speed of a floating object to be predicted can be predicted more accurately.

Classes IPC  ?

• G06F 30/20 - Optimisation, vérification ou simulation de l’objet conçu

Abrégé

A gas powered-type wave energy power supply subsurface buoy, which comprises a spindle-shaped subsurface buoy body (1); two ends of a Y-shaped armored optic-electric composite cable (16) are mounted at two ends of a short axis of the subsurface buoy body (1); a third end of the Y-shaped armored optic-electric composite cable (16) is connected to one end of a vertical armored optic-electric composite cable (17); the other end of the vertical armored optic-electric composite cable (17) is connected to a sunken anchoring block (18); a gas power loop electricity generation unit is mounted inside the subsurface buoy body (1); and a plane where the gas power loop electricity generation unit is located is perpendicular to the short axis of the subsurface buoy body (1).

Classes IPC  ?

• F03B 13/24 - Utilisation de l'énergie des vagues pour produire un déplacement d'air, p. ex. pour entraîner une turbine à air

Abrégé

A self-cleaning and anti-adhesion apparatus for marine instruments includes an installation frame. A first end of the installation frame is fixed with an installation base, and a second end of the installation frame is movable with a screw rod. The upper end of the installation base is movable with a first rotation base. A wire netting ball used for holding a sensor is installed above the first rotation base. The wire netting ball is fixedly connected with the installation base. The top end of the screw rod is fixedly connected with a first end of the flexible connector, and a second end of the flexible connector is fixedly connected with a floating bladder. The screw rod is screwed with an inner wheel of an internal meshing ratchet mechanism, and an outer wheel of the internal meshing ratchet mechanism is fixed inside the mounting ring.

Classes IPC  ?

• B08B 1/04 - Nettoyage par des procédés impliquant l'utilisation d'outils, de brosses ou d'éléments analogues utilisant des éléments actifs rotatifs
• B08B 1/00 - Nettoyage par des procédés impliquant l'utilisation d'outils
• B63B 59/08 - Dispositifs de nettoyage des coques des parties immergées à flot

Abrégé

A wave power generation glider and a working method therefor. The wave power generation glider comprises a floating body (1) and a wave glider which are connected by means of a traction rope assembly (2); a communication device (3), a positioning device (4), a control device (5), a power storage device (6), and an energy converter are arranged in the floating body (1), and the communication device (3), the positioning device (4), and the power storage device (6) are separately connected to the control device (5); the wave glider comprises a glider body (7), a plurality of wave power generation mechanisms (8) are disposed on two sides of the glider, the plurality of wave power generation mechanisms (8) are separately connected to the energy converter, and the energy converter is connected to the power storage device (6); each wave power generation mechanism comprises a rotating shaft, and two ends of the rotating shaft are respectively movably connected to the glider body (7) and a wing plate (11); each rotating shaft comprises a sleeve (9) and a movable rod (10) which is telescopic in the sleeve (9), and the corresponding wing plate (11) is connected to the movable rod (10). The wave power generation glider may implement gliding and power generation.

Classes IPC  ?

• F03B 13/20 - Utilisation du mouvement relatif entre un élément déplacé par les vagues et un autre élément les deux éléments étant mobiles par rapport au fond ou au bord de la mer
• F03B 11/00 - Parties constitutives ou détails non couverts par les groupes ou présentant un intérêt autre que celui visé par ces groupes
• B63H 19/04 - Propulsion marine non prévue ailleurs utilisant l'énergie due au mouvement ambiant de la mer, p. ex. au roulis ou au tangage par les courants marins
• B63H 21/17 - Aménagements de l'appareil moteur de propulsion ou de certains de ses éléments pour utilisation à bord des navires le navire étant actionné par moteurs par moteur électrique
• B63B 35/00 - Embarcations ou structures flottantes similaires spécialement adaptées à des finalités spécifiques et non prévues ailleurs

Abrégé

A marine float capable of avoiding marine hazards such as typhoons, and avoidance method thereof. The float comprises a float body (1). A cavity (2) is formed in the middle of the float body (1). An air bag (3) for driving the float body (1) to float after being inflated is arranged in the cavity (2). An air pipe (4) is installed at the top of the air bag (3). The top of the air pipe (4) extends to the outside of the float body (1). An air valve (5) is installed at the top of the air pipe (4). The arrangement height of the top of the air valve (5) is higher than that of the top of the float body (1). The bottom of the cavity (2) is provided with a normally open water passing pipe (6). The float is simple in structure and can reduce the probability of being completely destroyed by marine hazards such as typhoons.

Classes IPC  ?

• B63B 43/12 - Amélioration de la sécurité des navires, p. ex. contrôle des avaries, non prévue ailleurs réduisant le risque de chavirer ou de sombrer par augmentation de la flottabilité employant des caissons à air du bord
• B63B 22/18 - Coffres d'amarrage ou bouées comportant des moyens pour régler l'assiette ou la position, p. ex. des surfaces de réaction ou des orins

Abrégé

A deep-sea in-situ long-term experimental platform having a sediment sampling function, which relates to the field of deep sea apparatuses. The platform enables, by means of a multi-stage release mechanism, buoyancy to match gravity to complete an entire sampling recovery process of sediment, which only requires small power units to be sequentially triggered to complete intubation and sampling without a powerful power source to provide kinetic energy for vertical movement. The structure of the deep-sea in-situ long-term experimental platform is simplified, and moreover, the weight is reduced, the cost is reduced, and the reliability is further improved.

Classes IPC  ?

• G01N 1/12 - Pelles d'excavateursDragues
• B63B 35/00 - Embarcations ou structures flottantes similaires spécialement adaptées à des finalités spécifiques et non prévues ailleurs

Abrégé

Disclosed in the present invention is an intelligent solution injection device for a deep-sea sediment microorganism culture experiment. The intelligent solution injection device is mainly composed of an insertion device, a controllable slow-release solution injection system, an interstitial water displacement and monitoring system, and a deep-sea peristaltic pump. The insertion device can insert a solution injection needle tube and an interstitial water collection tube into a designated sediment position by means of gravity or other driving devices; the controllable slow-release solution injection system is used for receiving an instruction to inject a certain amount of culture solution into sediment through the solution injection needle tube; and the interstitial water displacement and monitoring system is used for collecting sediment interstitial water and monitoring environmental parameters to develop a solution injection policy. The present invention can simulate a diffusion process of matter seeping out of a deep-sea cold seep, and can provide a powerful tool for researchers to conduct long-term in-situ experiments of deep-sea sediment microorganisms.

Classes IPC  ?

• C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

The present invention provides potent antibiofilm and antifouling compounds albofungin and derivatives thereof isolated from Streptomyces chrestomyceticus BCC 24770, the construction of high-yield strains for albofungin production, and application of albofungin-based copolymer coatings to object or surfaces, particularly to inhibit fouling by marine organisms using hydrolysable and degradable antifouling coatings incorporated with albofungins.

Classes IPC  ?

• C09D 5/16 - Peintures antisalissuresPeintures subaquatiques
• C09D 5/14 - Peintures contenant des biocides, p. ex. fongicides, insecticides ou pesticides
• C09D 143/04 - Homopolymères ou copolymères de monomères contenant du silicium

Abrégé

Disclosed in the present application are a novel double-sided solid culture dish and use thereof, which relate to the fields of microculture, etc. The culture dish comprises an upper cover and a lower cover, a straight cylinder dish wall being arranged between the upper cover and the lower cover, and the upper cover, the lower cover and the straight cylinder dish wall forming a snap-fit structure; and a gauze type permeable membrane base, a grid-shaped fixing structure being arranged on the gauze type permeable membrane base, and "T"-shaped column structures being vertically arranged on joints or grid lines of the grid-shaped fixing structure. Culture dishes are formed between the gauze type permeable membrane base and the upper cover, and between the gauze type permeable membrane base and the lower cover respectively, and a solidified culture medium is made into the stable double-sided solid culture dish since the "T"-shaped column structures on the gauze type permeable membrane base and a circle of boss structure perpendicular to the wall of the straight cylinder dish wall jointly support a solid culture medium to be not separated from the gauze type permeable membrane base. According to the culture dish, double-sided preparation and the use of the solid culture medium and information exchange and interaction of double-sided microorganisms are achieved, such that related researches of non-contact interaction between microorganisms or interaction between the microorganisms and an environment become simple, convenient, rapid and efficient.

Classes IPC  ?

• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12M 1/22 - Boîtes de Pétri
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

The subject invention pertains to compositions comprising albofungin and/or derivatives thereof, including, chloroalbofungin, 477-albo, 492-albo, 505-albo, 506-1-albo, 506-2-albo, 519-albo, and 562-albo. The subject invention further pertains to methods of treating a subject with HIV using albofungin and/or derivatives thereof, including, chloroalbofungin, 477-albo, 492-albo, 505-albo, 506-1-albo, 506-2-albo, 519-albo, and 562-albo.

Classes IPC  ?

• C07D 491/052 - Systèmes condensés en ortho avec un seul atome d'oxygène comme hétéro-atome du cycle contenant de l'oxygène le cycle contenant de l'oxygène étant à six chaînons
• C07D 491/16 - Système condensés en péri
• A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
• A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV

Abrégé

A self-cleaning anti-adhesion apparatus for a marine instrument, comprising a mounting frame (1), wherein one end of the mounting frame (1) is fixedly provided with a mounting seat (2), the other end of the mounting frame (1) is movably provided with a screw rod (3), and the upper end of the mounting seat (2) is movably provided with a first rotating seat (4); a metal mesh ball (5) used for accommodating a sensor is mounted above the first rotating seat (4), and the metal mesh ball (5) is fixedly connected to the mounting seat (2); the top end of the screw rod (3) is fixedly connected to one end of a flexible connecting piece (6), and the other end of the flexible connecting piece (6) is fixedly connected to a floating bag (7); the screw rod (3) is in threaded connection with an inner wheel of an internally engaged ratchet mechanism (8), an outer wheel of the internally engaged ratchet mechanism (8) is movably mounted on the inner side of a mounting ring (9), and the mounting ring (9) is fixedly connected to the mounting frame (1); the outer wheel of the internally engaged ratchet mechanism (8) is fixedly connected to a second rotating seat (10); a rotating ring (11) is fixedly arranged between the first rotating seat (4) and the second rotating seat (10), and the inner wall of the rotating ring (11) is provided with a brush (12); the rotating ring (11) can be driven by the upper buoyancy of natural wave energy to clean the outer wall of the metal mesh ball (5) without other energy sources, which ensures that the sensor mounted in the metal mesh ball (5) is not obstructed.

Classes IPC  ?

• G01D 11/00 - Parties constitutives des dispositions pour la mesure qui ne sont pas spécialement adaptées à une variable particulière
• G01D 3/08 - Dispositions pour la mesure prévues pour les objets particuliers indiqués dans les sous-groupes du présent groupe avec dispositions pour protéger l'appareil, p. ex. contre les fonctionnements anormaux, contre les pannes
• B08B 1/04 - Nettoyage par des procédés impliquant l'utilisation d'outils, de brosses ou d'éléments analogues utilisant des éléments actifs rotatifs

Abrégé

The subject invention pertains to compositions and methods of coating objects using BOC-butenolide. The invention also relates to compositions and methods for enhancing the performance and longevity of the coated objects with BOC-butenolide, including inhibiting fouling often caused by marine organisms.

Classes IPC  ?

• A01N 47/12 - Dérivés de l'acide carbamique, c.-à-d. contenant le groupe —O—CO—NLeurs thio-analogues contenant un groupe —O—CO—N, ou un de ses thio-analogues, non directement lié à un cycle et l'atome d'azote n'étant pas un chaînon d'un hétérocycle
• A01N 25/10 - Composés macromoléculaires
• A01P 15/00 - Biocides utilisés à des fins particulières non prévues dans les groupes
• A61L 31/16 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques

Abrégé

The subject invention pertains to compositions and methods for treating neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), multiple sclerosis, epilepsy, stroke, alcohol withdrawal, progressive supranuclear palsy (PSP), Pick's disease (PiD), corticobasal degeneration (CBD), frontotemporal dementia or parkinsonism linked to chromosome 17 (FTDP-17). The methods of the subject invention further relate to methods of fermentation of bacterial cells and methods of tautomerization of the subject compounds.

Classes IPC  ?

• C07D 407/12 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
• C07D 493/04 - Systèmes condensés en ortho

Abrégé

The present application is applicable to the technical field of data processing, and provides a data correction method and apparatus, a terminal device and a storage medium. Said method comprises: determining, according to electromagnetic time sequence data and temperature data which are acquired by submarine electromagnetic acquisition stations, a time period temperature corresponding to the electromagnetic timing data in each time period; determining, according to a preset time correction template, a time error corresponding to each time period temperature, the preset time correction template being used for representing changes in time errors of clocks on the submarine electromagnetic acquisition stations due to the duration of different temperatures; and correcting the electromagnetic time sequence data on the basis of the time error corresponding to each time period temperature. Thus, the clock time of each acquisition station can be corrected, the synchronization accuracy of electromagnetic time sequence data of each acquisition station is ensured, and the application effect of the submarine electromagnetic remote reference synchronization technology is improved.

Classes IPC  ?

• G01V 3/38 - Traitement de données, p. ex. pour l'analyse, pour l'interprétation ou pour la correction

Abrégé

The present application is applicable to the technical field of signal processing, and provides a signal processing method and apparatus, a terminal device and a storage medium. The signal processing method comprises: performing signal feature extraction on a submarine electromagnetic detection signal to obtain signal features of the submarine electromagnetic detection signal; and performing, according to the signal features, denoising processing on the submarine electromagnetic detection signal by using a preset signal denoising network, to obtain a denoised submarine electromagnetic detection signal, the signal denoising network being trained by using submarine electromagnetic signal noise samples. Thus, noise and electromagnetic signals in the submarine electromagnetic detection signal can be identified according to the signal features learned by the signal denoising network, and the noise can be removed from the submarine electromagnetic detection signal, so as to specifically perform noise identification and denoising on submarine electromagnetic detection signals in a complex marine environment, thereby optimizing the denoising effect of the submarine electromagnetic detection signals, and effectively improving the quality of the submarine electromagnetic detection signals.

Classes IPC  ?

• G01V 3/12 - Prospection ou détection électrique ou magnétiqueMesure des caractéristiques du champ magnétique de la terre, p. ex. de la déclinaison ou de la déviation fonctionnant par ondes électromagnétiques
• G01V 3/38 - Traitement de données, p. ex. pour l'analyse, pour l'interprétation ou pour la correction
• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales