Abrégé

The present disclosure relates to an assay method for detection of target nucleic acid. The method includes immobilizing a guide RNA (gRNA) to an immobilization surface; complexing a Cas enzyme to the gRNA; adding a target nucleic acid; labeling the target nucleic acid; detecting the target nucleic acid without amplification; and determining one or more results based on the detected target nucleic acid via a reader.

Produits et services

Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences.

Produits et services

(1) Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences.

Produits et services

Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences.

Produits et services

Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences.

Produits et services

Research and scientific research consulting in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences

Produits et services

(1) Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences.

Produits et services

(1) Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences.

Produits et services

Scientific research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences

Produits et services

Scientific research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences

Abrégé

A gas chromatography instrument is provided that is capable of analyzing samples both quickly and accurately. The detector includes a first unit and a second unit that alternate between collection mode and desorption mode. This allows one unit to collect the sample, while the other unit desorbs another sample before the units switch operations. The alternating collection and desorption modes allows the detector to generate a data point approximately every thirty seconds, with each alternating unit.

Classes IPC  ?

• G01N 30/74 - Détecteurs optiques
• G01N 30/54 - Température
• G01N 30/06 - Préparation

Abrégé

A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.

Classes IPC  ?

• A47C 9/00 - Tabourets à usages particuliers
• A45C 5/03 - Valises
• A45C 5/04 - MallesPaniers de voyage
• A45C 5/06 - Bagages rigides ou semi-rigides comportant des compartiments extérieurs
• A47B 3/10 - Tables de voyage ou tables-malles

Abrégé

Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.

Classes IPC  ?

• C07C 309/73 - Esters d'acides sulfoniques ayant des atomes de soufre de groupes sulfo estérifiés liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné à des atomes de carbone de cycles aromatiques à six chaînons non condensés
• A61P 35/00 - Agents anticancéreux
• C07C 215/10 - Composés contenant des groupes amino et hydroxy liés au même squelette carboné ayant des groupes hydroxy et des groupes amino liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant saturé et acyclique avec un groupe amino et au moins deux groupes hydroxy liés au squelette carboné
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/08 - Solutions

Abrégé

A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The present mobile laboratory is configured in a footlocker configuration including a plurality of different compartments specifically configured for holding all of the necessary equipment for use in a wide variety of different applications including successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source. The present mobile laboratory includes a deployable workbench area which provides a stable workstation when the footlocker configuration is deployed.

Classes IPC  ?

• B01L 9/02 - Paillasses ou tables de laboratoireLeurs garnitures
• A45F 4/02 - Sacs ou ballots transformables en d'autres articles
• C12Q 1/686 - Réaction en chaine par polymérase [PCR]
• A45F 3/04 - Sacs ou paquetages portés sur le corps au moyen de deux courroies passant sur les épaules
• A45C 5/04 - MallesPaniers de voyage
• B01L 1/00 - EnceintesChambres
• A45C 5/14 - Bagages rigides ou semi-rigides comportant des moyens de roulement incorporés
• A45C 7/00 - Bagages, sacs ou articles similaires pliants ou extensibles
• A45F 3/00 - Articles de voyage ou de campingSacs ou paquetages portés sur le corps
• A45C 9/00 - Bagages ou sacs transformables en objets destinés à un autre usage

Abrégé

Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.

Classes IPC  ?

• A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
• A61P 35/00 - Agents anticancéreux

Abrégé

Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.

Classes IPC  ?

• A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
• A61P 35/00 - Agents anticancéreux

Produits et services

Research and analysis in the fields of economics and business management services Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences

Abrégé

The high temperature/high pressure (HTHP) reactor of the present invention includes a main cylinder, a reversible piston inside the cylinder that divides the main cylinder into a pressurization chamber and a reactor chamber, a thermal jacket, a lid and an end cap, wherein the HTHP reactor is configured to facilitate microbial growth in the reactor chamber that provides high temperature and high pressure conditions that simulate resource reservoir conditions, wherein the resource may be an oil reservoir. The HTHP chamber of the present invention is also configured to allow the use of a variety of instrumentation and valves that can be customized to allow a user to monitor desired physical properties within the reaction chamber and the microbial behavior and byproducts. This information is used to create an individual treatment plan for a reservoir to maximize the resource recovery, for example during Microbiobial Enhanced Oil Recovery (MEOR).

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Produits et services

Research and consultation in the field of economics and business management services Research and consultation in the fields of physical sciences, biological sciences, mathematics, engineering sciences and chemical sciences

Produits et services

Providing facilities for scientific research in the nature of solar energy and renewable resources; consulting services for conducting research relating to renewable energy; research in the field of renewable energy and solar energy

Produits et services

RESEARCH AND CONSULTATION IN THE FIELDS OF THE PHYSICAL SCIENCES, BIOLOGICAL SCIENCES, ENGINEERING SCIENCES, AND ECONOMICS AND MANAGEMENT SCIENCES