|
2024
|
Invention
|
Heterocyclics as egfr inhibitors. The present application relates to EGFR inhibitor compounds of ... |
|
2023
|
Invention
|
Novel protease inhibitors for treatment of coronavirus infections. Disclosed is a compound repres... |
|
|
Invention
|
Methods of treating cancer. The present application relates to compounds of Formula (I), as defin... |
|
|
Invention
|
Tricyclic compounds. The present application relates to compounds of Formula (I), as defined here... |
|
|
Invention
|
3-(1h-indole-2-carbonyl)-6,6-dimethyl-n-((s)-1-oxo-3-((s)-2-oxopyrrolidin-3-yl)p ropan-2-yl)-3-az... |
|
|
Invention
|
Cyclic compounds and methods of using same. The present application relates to compounds of Formu... |
|
|
Invention
|
Phenyl amide compounds and methods of use. The present application relates to compounds of Formul... |
|
|
Invention
|
Methods for predicting an active set of compounds having alternative cores, and drug discovery me... |
|
|
Invention
|
Accounting for induced fit effects.
A system, device, and method for predicting a docked positio... |
|
|
Invention
|
Heterocyclic compounds and methods of use. The present application relates to compounds of Formul... |
|
2022
|
Invention
|
Heterocyclic compounds and methods of use.
The present application relates to compounds of Formu... |
|
|
Invention
|
Cyclic compounds and methods of using same.
The present application relates to compounds of Form... |
|
|
Invention
|
Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disorders.
Th... |
|
|
Invention
|
Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disorders. The... |
|
|
Invention
|
Fused heterocycles and uses of same. The present application relates to compounds of Formula (I),... |
|
2021
|
Invention
|
Heterocyclic pericondensed cdc7 kinase inhibitors for the treatment of cancer.
The present appli... |
|
|
Invention
|
Heterocyclic pericondensed cdc7 kinase inhibitors for the treatment of cancer. The present applic... |
|
|
Invention
|
Substituted dihydropyrazinediones as modulators of the nmda receptor. This present application re... |
|
2020
|
Invention
|
Computational screening of candidate compounds.
A method for computing free energy difference be... |
|
2018
|
Invention
|
Accounting for induced fit effects. A system, device, and method for predicting a docked position... |
|
|
Invention
|
Predicting an active set of compounds having alternative cores. A system, device, and method for ... |
|
2017
|
Invention
|
Graphical user interface for chemical transition state calculations.
A computer-implemented meth... |
|
|
Invention
|
Graphical user interface for chemical transition state calculations. A computer-implemented metho... |
|
|
Invention
|
Methods and systems for calculating free energy differences using an alchemical restraint potenti... |
|
2015
|
Invention
|
Collaborative drug discovery system. Methods and systems for drug discovery collaboration provide... |
|
2013
|
Invention
|
Methods and systems for calculating free energy differences using a modified bond stretch potenti... |
|
2011
|
Invention
|
Binding affinity scoring function penalizing compounds which make unfavorable hydrophobic contact... |
|
2008
|
Invention
|
Core hopping.
An optimized compound is derived from a reference compound by replacing its core, ... |
|
|
Invention
|
Binding affinity scoring function including factor for environs of ring or bulky rigid group. Sco... |
