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2024
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P/S
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Research and development in the field of gene, genome, or cellular editing technology for medical... |
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Invention
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Assays for analysis of ribonucleic acid (rna) molecules. In certain aspects, the disclosure relat... |
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Invention
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Systems, devices, and methods of a data pipeline.
Disclosed are data pipelines for string extrac... |
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Invention
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Systems, devices, and methods of a data pipeline. Disclosed are data pipelines for string extract... |
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Invention
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Ionizable amine lipids. The disclosure provides ionizable lipids and lipid nanoparticle (LNP) com... |
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Invention
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Modified guide rnas for gene editing.
This disclosure relates to modified guide RNAs having impr... |
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Invention
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Polynucleotides, compositions, and methods for genome editing.
Compositions and methods for gene... |
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P/S
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Organizing and recruiting patients for clinical trials for the treatment of hereditary angioedema... |
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Invention
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Cish compositions and methods for immunotherapy. CISHCISH gene are provided. Compositions and met... |
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Invention
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Compositions and methods for hepatitis b virus (hbv) genome editing. Compositions and methods are... |
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Invention
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Programmed cell death protein 1 (pd1) compositions and methods for cell-based therapy.
Compositi... |
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Invention
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Compositions and methods for treatment of diseases associated with trinucleotide repeats in trans... |
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2023
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Invention
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Systems and methods for genomic editing. Methods and compositions for genetically modifying a cel... |
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Invention
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Methods for analyzing nucleic acid cargos of lipid nucleic acid assemblies. The present disclosur... |
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Invention
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Compositions and methods for proprotein convertase subtilisin kexin 9 (pcsk9) editing. PCSK9PCSK9... |
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Invention
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Compositions and methods for immunooncology.
The present invention is directed to genome editing... |
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Invention
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Modified guide rnas comprising an internal linker for gene editing.
This disclosure relates to m... |
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Invention
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Natural killer cell receptor 2b4 compositions and methods for immunotherapy.
Compositions and me... |
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Invention
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Lymphocyte activation gene 3 (lag3) compositions and methods for immunotherapy.
Compositions and... |
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Invention
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T-cell immunoglobulin and mucin domain 3 (tim3) compositions and methods for immunotherapy.
Comp... |
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Invention
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Compositions and methods comprising a ttr guide rna and a polynucleotide encoding an rna-guided d... |
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Invention
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Compositions and methods for kallikrein (klkb1) gene editing.
Compositions and methods for editi... |
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Invention
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Klkb1. in vivoKLKB1in vivo KLKB1KLKB1 gene by systemically administering a lipid nanoparticle com... |
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Invention
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Engineered t cells. The present disclosure relates to T cells engineered to comprise a heterologo... |
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Invention
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Compositions and methods for genetically modifying ciita in a cell.
Compositions and methods for... |
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Invention
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Compositions and methods for reducing hla-a in a cell.
Compositions and methods for reducing HLA... |
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Invention
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Compositions and methods for genomic editing. Neisseria meningitidise.ge.g., in adoptive cell tra... |
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Invention
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Compositions and methods for reducing mhc class i in a cell. e.ge.g., in adoptive cell transfer t... |
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Invention
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Methods and compositions for genetically modifying a cell. Methods and compositions for genetical... |
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Invention
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Compositions and methods for reducing mhc class ii in a cell.
Compositions and methods for reduc... |
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Invention
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Polynucleotides, compositions, and methods for genome editing involving deamination.
Polynucleot... |
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Invention
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Stabilized nucleic acids encoding messenger ribonucleic acid (mrna).
This disclosure relates to ... |
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Invention
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Chimeric antigen receptor compositions and uses. Compositions and methods for expressing a chimer... |
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P/S
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Organizing and recruiting patients for clinical trials for the treatment of transthyretin (ATTR) ... |
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Invention
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Crispr-mediated transgene insertion in neonatal cells. Compositions and methods for inserting a n... |
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2022
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Invention
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Compositions and methods for ttr gene editing and treating attr amyloidosis. Compositions and met... |
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Invention
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Compositions and methods for treating alpha-1 antitrypsin deficiency.
Compositions and methods f... |
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Invention
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Cd38 compositions and methods for immunotherapy. Compositions and methods for editing, e.g., alte... |
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Invention
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Polynucleotides, compositions, and methods for genome editing. N. meningitidisN. meningitidis Cas... |
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Invention
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Modified guide rnas for gene editing. This disclosure relates to modified guide RNAs having impro... |
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Invention
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Polynucleotides, compositions, and methods for genome editing. Compositions and methods for gene ... |
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Invention
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Modified guide rnas for gene editing. in vitro in vivo N. meningitidisN. meningitidis Cas9 (NmeCa... |
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Invention
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Methods of in vitro cell delivery.
Compositions and methods for multiplex delivery and gene edit... |
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Invention
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Compositions and methods for the treatment of hemoglobinopathies.
The present invention is direc... |
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Invention
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Modified guide rnas. This disclosure relates to modified single and dual guide RNAs having improv... |
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Invention
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Lipid nanoparticle formulations for crispr/cas components.
The invention provides lipid nanopart... |
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Invention
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Inhibitors of dna-dependent protein kinase and compositions and uses thereof.
The present disclo... |
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Invention
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Lipid nanoparticles compositions.
The disclosure provides lipid nanoparticle (LNP) compositions ... |
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2021
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Invention
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Engineered t cells.
The present disclosure relates to T cells engineered to comprise a modificat... |
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Invention
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Methods and compositions for ocular cell therapy.
The present invention provides ocular cells, g... |
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2018
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Invention
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Formulations.
The invention provides lipid nanoparticle-based compositions with improved propert... |
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2016
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P/S
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Pharmaceutical and biological preparations to be delivered or applied ex vivo to human cells base... |
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2015
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P/S
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Pharmaceutical and biological preparations based on gene, genome and cellular editing, modulation... |
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P/S
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Pharmaceutical and biological preparations and diagnostic
products based on gene, genome and cel... |
