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2024
|
Invention
|
Immediate release pharmaceutical formulation of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbony... |
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2023
|
Invention
|
Dna damage repair inhibitors for treatment of cancer.
The present invention relates to the recog... |
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2022
|
Invention
|
Immediate release pharmaceutical formulation of 4-[3-(4- cyclopropanecarbonyl-piperazine-1-carbon... |
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2021
|
Invention
|
Phthalazinone derivatives.
Compounds of the formula (I):
Compounds of the formula (I):
C... |
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2019
|
Invention
|
Phthalazinone derivatives. Compounds of the formula (I):
1 is selected from H and halo.
|
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2017
|
Invention
|
Pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors. There is provided a comp... |
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2014
|
Invention
|
Phthalazinone derivatives. Compounds of the formula (I):
1 is selected from H and halo.
|
|
2010
|
Invention
|
Dibenzothiophene derivatives as dna- pk inhibitors. Compound formula I: wherein: X1 and X2 may be... |
|
2009
|
Invention
|
Phthalazinone derivative. 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H... |
|
|
Invention
|
Dna-pk inhibitors.
A compound of formula (I) wherein: R1 and R2 are independently selected from ... |
|
|
Invention
|
Dna-pk inhibitors. A compound of formula (I) wherein: R1 and R2 are independently selected from h... |
|
2008
|
Invention
|
4- [3- (4-cyclopropanecarbonyl-piperazine-i-carbonyl) -4 -fluoro-benzyl] -2h-phthalaz in-1-one. 4... |
|
|
Invention
|
Crystalline form l 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phthal... |
|
|
Invention
|
Atm inhibitors.
A compound of formula I:
A compound of formula I:
A compound of formula ... |
|
|
Invention
|
Dna-pk inhibitors.
A compound of formula I:
A compound of formula I:
A compound of formu... |
|
|
Invention
|
Dna pk inhibitors. A compound of formula (I): wherein: R1 and R2 are independently selected from ... |
|
|
Invention
|
Dna-pk inhibitors. A compound of formula I:
1-7 alkyl.
|
|
|
Invention
|
Phthalazinone derivatives.
A compound of the formula (I):
A compound of the formula (I):
... |
|
|
Invention
|
Phthalazinone derivatives and their use as medicament to treat cancer. A compound of the formula ... |
|
|
Invention
|
Phthalazinone derivatives. A compound of the formula (I) wherein: A and B together represent an o... |
|
2007
|
Invention
|
Phthalazinone derivatives. 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2... |
|
|
Invention
|
Method of preparing crystalline form phthalazinone derivative for use in cancer treatment. The pr... |
|
|
Invention
|
Polymorphic form of 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2h-phtha... |
|
|
Invention
|
Pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors.
There is provided a com... |
|
|
Invention
|
2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors. There... |
|
|
Invention
|
Methods of increasing the sensitivity of cancer cells to dna damage. The present invention relate... |
|
|
Invention
|
Synthesis of 2-amino-substituted 4-oxo-4h-chromen-8.yl-trifluoro-methanesulfonic acid esters.
A ... |
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|
Invention
|
Synthesis of 2-amino-substituted 4-oxo-4h-chromen-8.yl-trifluoro-methanesulfonic acid esters. A m... |
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|
Invention
|
2 -oxyheteroarylamide derivatives as parp inhibitors.
A compound of the formula (I): and pharmac... |
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|
Invention
|
2 -oxybenzamide derivatives as parp inhibitors.
A compound of the formula (I): and pharmaceutica... |
|
|
Invention
|
Parp inhibitors.
A compound of the formula (I), and pharmaceutically acceptable salts thereof, w... |
