| 2025 | P/S | Vaccines for human use | 
				    			
				    				
				    					|  | P/S | Vaccines for human use. | 
				    			
				    				
				    					|  | P/S | vaccines for human use. | 
				    			
				    				
				    					|  | P/S | Vaccines for human use | 
				    			
				    				
				    					|  | P/S | Providing medical information via a website | 
				    			
				    				
				    					|  | Invention | Epstein-barr virus vaccines. 
The disclosure relates to EBV ribonucleic acid vaccines as well as ... | 
				    			
				    				
				    					|  | Invention | Tolerizing antigen specific immunotherapies. Provided are amino acid and nucleic acid sequences t... | 
				    			
				    				
				    					|  | Invention | Bromodomain and extra-terminal domain (bet) epigenetic reader decoy. Present disclosure provides ... | 
				    			
				    				
				    					|  | Invention | High purity rna compositions and methods for preparation thereof. 
The invention relates to impro... | 
				    			
				    				
				    					|  | Invention | Synthetic nucleic acids and methods of using the same for improved polypeptide production. This d... | 
				    			
				    				
				    					|  | Invention | Lipid nanoparticle compositions comprising sialic acid derivatives and the uses thereof. The pres... | 
				    			
				    				
				    					|  | Invention | Methods of preparing lipid nanoparticles. The present disclosure provides methods of preparing li... | 
				    			
				    				
				    					|  | Invention | Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the... | 
				    			
				    				
				    					|  | Invention | Ionizable lipids and compositions thereof for delivery of therapeutic agents. The disclosure feat... | 
				    			
				    				
				    					|  | Invention | Compositions and methods for detecting dsrna. 
The present disclosure relates generally to antibo... | 
				    			
				    				
				    					|  | Invention | Influenza vaccine. The invention relates to compositions and methods for the preparation, manufac... | 
				    			
				    				
				    					| 2024 | Invention | Betacoronavirus mrna vaccines. 
The disclosure relates to ribonucleic acid (RNA) vaccines and com... | 
				    			
				    				
				    					|  | Invention | Betacorona virus mrna vaccines. The disclosure relates to ribonucleic acid (RNA) vaccines and com... | 
				    			
				    				
				    					|  | Invention | Novel cas nucleases and polynucleotides encoding the same. The present disclosure provides novel ... | 
				    			
				    				
				    					|  | Invention | Compounds and compositions for intracellular delivery of therapeutic agents. 
The disclosure feat... | 
				    			
				    				
				    					|  | Invention | Polynucleotides encoding glucose-6-phosphatase for the treatment of glycogen storage disease. 
Th... | 
				    			
				    				
				    					|  | Invention | Rna polymerase variants. 
The present disclosure provides, in some aspects, variant RNA polymeras... | 
				    			
				    				
				    					|  | Invention | Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of... | 
				    			
				    				
				    					|  | Invention | Concatemeric peptide epitope rnas. 
The invention relates to concatemeric peptide epitope RNAs, a... | 
				    			
				    				
				    					|  | Invention | Rna polymerase variants for co-transcriptional capping. 
The present disclosure provides RNA poly... | 
				    			
				    				
				    					|  | Invention | Human cytomegalovirus vaccine. 
The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, a... | 
				    			
				    				
				    					|  | Invention | Nucleic acid vaccines for varicella zoster virus (vzv). 
Aspects of the disclosure relate to nucl... | 
				    			
				    				
				    					|  | Invention | Peg lipids and uses thereof. 
The present disclosure in part provides compounds (i.e., PEG lipids... | 
				    			
				    				
				    					|  | Invention | Polynucleotides containing a stabilizing tail region. 
The invention features polynucleotides enc... | 
				    			
				    				
				    					|  | Invention | Immunoglobulin a protease polypeptides, polynucleotides, and uses thereof. This disclosure relate... | 
				    			
				    				
				    					|  | Invention | Humanized anti-cd3 binding molecules and uses thereof. Described herein are humanized anti-CD3 an... | 
				    			
				    				
				    					|  | Invention | Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria. in vivoi... | 
				    			
				    				
				    					|  | Invention | Delivery and formulation of engineered nucleic acids. Provided are formulations, compositions and... | 
				    			
				    				
				    					|  | Invention | Delivery and formulation of engineered nucleic acids. 
Provided are formulations, compositions an... | 
				    			
				    				
				    					|  | Invention | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof. The present disclosure pr... | 
				    			
				    				
				    					|  | Invention | Rna cancer vaccines. 
The disclosure relates to cancer ribonucleic acid (RNA) vaccines, as well a... | 
				    			
				    				
				    					|  | Invention | Respiratory syncytial virus vaccine. 
The disclosure relates to respiratory syncytial vims (RSV) ... | 
				    			
				    				
				    					|  | Invention | Messenger ribonucleic acids for enhancing immune responses and methods of use thereof. 
The discl... | 
				    			
				    				
				    					|  | Invention | Terminally modified rna. 
The invention relates to compositions and methods for the manufacture a... | 
				    			
				    				
				    					| 2023 | Invention | Ribosomal engagement potency assay. 
Provided herein are methods for detecting and/or measuring m... | 
				    			
				    				
				    					|  | Invention | Rna polymerase variants. 
RNA polymerase variants enable high efficiency transcription of RNA. In... | 
				    			
				    				
				    					|  | Invention | Detection of mrna purity in a mixture. 
Provided herein are methods of detecting mRNA purity in a... | 
				    			
				    				
				    					|  | Invention | Cross mixers for lipid nanoparticle production, and methods of operating the same. 
The present d... | 
				    			
				    				
				    					|  | Invention | Messenger ribonucleic acids with extended half-life. 
The disclosure features a polynucleotide en... | 
				    			
				    				
				    					|  | Invention | Polynucleotides encoding fanconi anemia, complementation group proteins for the treatment of fanc... | 
				    			
				    				
				    					|  | Invention | Mrnas encoding checkpoint cancer vaccines and uses thereof. 
The disclosure features lipid nanopa... | 
				    			
				    				
				    					|  | Invention | Mucosal administration methods and formulations. 
The present disclosure provides compositions an... | 
				    			
				    				
				    					|  | Invention | Continuous precipitation for mrna purification. 
Aspects of the disclosure relate to methods of p... | 
				    			
				    				
				    					|  | Invention | In vitro transcription dna purification and recycling. 
Provided herein are methods of preparing ... | 
				    			
				    				
				    					| 2022 | Invention | Compounds and compositions for delivery of therapeutic agents. 
The disclosure features novel lip... | 
				    			
				    				
				    					|  | Invention | Lipid amines. 
The present invention relates to lipid amine compounds of formula (A1) which are u... | 
				    			
				    				
				    					|  | Invention | Drug product surrogate solutions. 
Provided herein are methods and compositions of a surrogate mR... | 
				    			
				    				
				    					|  | Invention | Composition of mrna-encoded il15 fusion proteins and methods of use thereof. 
The present disclos... | 
				    			
				    				
				    					|  | Invention | Lipid nanoparticle formulations and methods of synthesis thereof. 
Stabilized formulations of lip... | 
				    			
				    				
				    					|  | Invention | Extraction-less reverse phase (rp) chromatography of mrna encapsulated in lipid nanoparticles for... |