05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
35 - Advertising and business services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Antiseptics; chemico-pharmaceutical preparations;
anaesthetics; pharmaceutical preparations; vaccines;
anti-inflammatory preparations; pharmaceuticals for the
treatment of infectious diseases; pharmaceutical
preparations to be inhaled for the prevention and treatment
of respiratory diseases and disorders; pharmaceuticals for
the treatment of cancer; balsamic preparations for medical
purposes; drugs for medical purposes; biological
preparations for medical purposes; medicines for human
purposes; diagnostic reagents for medical purposes;
pharmaceuticals for the treatment of viral diseases;
diagnostic preparations for medical purposes. Testing apparatus for medical purposes; medical apparatus
and instruments. Retail or wholesale services for medical supplies; retail or
wholesale services for medicines; retail or wholesale
services for pharmaceutical preparations; marketing; sales
promotion for others. Drug development; pharmaceutical research; clinical trials.
The present application relates to a compound as represented by formula I, an isomer, an isotope marker or a pharmaceutically acceptable salt thereof, and the uses thereof as an ATR kinase inhibitor and for treating cancers, wherein each group is as defined herein.
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
The present invention relates to a compound as represented by formula I, a pharmaceutically acceptable salt, an isomer, or an isotope marker thereof. The compound can be used as an LSD1 inhibitor, and can also be used for preventing or treating tumors such as hematological neoplasms and small cell lung cancer.
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Retail or wholesale services for medical supplies; retail or wholesale services for medicines; retail or wholesale services for pharmaceutical preparations; marketing; sales promotion for others. Antiseptics; chemico-pharmaceutical preparations; anaesthetics; pharmaceutical preparations; vaccines; anti-inflammatory preparations; pharmaceuticals for the treatment of infectious diseases; pharmaceutical preparations to be inhaled for the prevention and treatment of respiratory diseases and disorders; pharmaceuticals for the treatment of cancer; balsamic preparations for medical purposes; drugs for medical purposes; biological preparations for medical purposes; medicines for human purposes; diagnostic reagents for medical purposes; pharmaceuticals for the treatment of viral diseases; diagnostic preparations for medical purposes. Testing apparatus for medical purposes; medical apparatus and instruments. Drug development; pharmaceutical research; clinical trials.
05 - Pharmaceutical, veterinary and sanitary products
35 - Advertising and business services
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
Medical genetic characteristics test reagents; antiseptics;
bath preparations for medical purposes;
chemico-pharmaceutical preparations; anaesthetics;
pharmaceutical preparations; vaccines; medicine cases,
portable, filled; lotions for pharmaceutical purposes;
liniments; nutritive substances for microorganisms;
sedatives; styptic preparations; chemical preparations for
pharmaceutical purposes; medicinal drinks; medicated soap;
medicines in form of tablet form; medicinal oil solutions;
prepared Chinese medicines; tonics [medicines];
immunostimulants; liquid medicines; adhesive patches for
medical purposes; blood products; anti-inflammatory
preparations; pharmaceuticals for the treatment of
infectious diseases; pharmaceutical preparations to be
inhaled for the prevention and treatment of respiratory
diseases and disorders; slimming pills; injectable medicinal
solutions; medicinal ointments; biochemical medicines;
pharmaceuticals for the treatment of cancer; pharmaceutical
preparations for the treatment of hypercholesteremia;
nutraceutical preparations for therapeutic or medical
purposes; tinctures for medical purposes; active
pharmaceutical ingredient; bacteriological preparations for
medical purposes; pharmaceutical preparations for the
treatment of hyperlipidemia; oral care preparations,
medicated; reagents for use in medical genetic testing;
medicinal alcohol; balsamic preparations for medical
purposes; capsules for medicines; vitamin preparations;
disinfectants; drugs for medical purposes; medicinal tea;
suppositories; biological preparations for medical purposes;
medicines for human purposes; chemical reagents for medical
or veterinary purposes; diagnostic reagents for medical
purposes; pharmaceuticals for the treatment of viral
diseases; medical immunoassay reagents; chemical
preparations for the diagnosis of pregnancy; pharmaceutical
preparations for skin care; diagnostic preparations for
medical purposes; antibiotics; dietetic foods adapted for
medical purposes; nutritional supplements; food for babies;
dietetic beverages adapted for medical purposes; infant
formula; depuratives; medicines for veterinary purposes;
pesticides; biocides; bandages for dressings; babies'
diapers; dressings, medical; wadding for medical purposes;
pants, absorbent, for incontinence; medicinal health kit;
eyepatches for medical purposes; adhesive tapes for medical
purposes; tissues impregnated with pharmaceutical lotions;
disinfectant wipes; surgical glues; dental abrasives; teeth
filling material; dental mastics; alloys of precious metals
for dental purposes; diapers for pets. Retail or wholesale services for medical supplies; retail or
wholesale services for sanitary preparations; retail or
wholesale services for medicines; retail or wholesale
services for pharmaceutical preparations. Grinding; processing of medicinal materials; services of a
dental technician; processing of chemical reagents. Drug development; pharmaceutical product evaluation;
pharmaceutical research; conducting early evaluations in the
field of new pharmaceuticals; scientific research and
development; scientific investigations for medical purposes;
technological research; pharmaceutical research; chemical
research; cosmetic research; biochemical research and
analysis; biological research; clinical trials;
bacteriological research; biological cloning services; DNA
screening for scientific research purposes; bacteriological
research and analysis; material testing.
40 - Treatment of materials; recycling, air and water treatment,
Goods & Services
Sales promotion services for third parties; commercial
administration of the licensing of the goods and services of
others; presentation of goods on communication media, for
retail purposes. Medicinal materials processing; processing of chemical
reagents.
40 - Treatment of materials; recycling, air and water treatment,
Goods & Services
Sales promotion services for third parties; business assistance, advisory and consulting services in the field of commercial administration of the licensing of the goods and services of others; presentation of goods on all forms of media communications stations, systems, networks, and services for the purpose of promoting the goods and services of others Medicinal materials processing, comprising slicing, steaming and soaking of medicinal materials; processing of chemical reagents used for preparation, production and application guidance of polymerace chain reaction (PCR) agents for testing of samples such as serum, sputum and secretions as well as for preparation, production and application guidance of biochemical agents used in testing of samples such as blood and body fluids
8.
A PHARMACEUTICAL COMPOSITION FOR TREATING GOUT AND ITS PREPARATION AND USE
A pharmaceutical composition for treating gout and its application in preparation of medicines for treating gout are provided. The said pharmaceutical composition comprises effective amount of febuxostat or its pharmaceutical salts or its solvates and a uric acid eliminant.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
40 - Treatment of materials; recycling, air and water treatment,
Goods & Services
Medical paste; chemico-pharmaceutical preparations;
medicines for human purposes; dressings (medical); tissue
paper impregnated with disinfectants; teeth filling
material; medicinal drinks; adhesive tapes for medical
purposes; dietetic food preparations adapted for medical
purposes; solutions for contact lenses. Dental apparatus; hearing aids for the deaf;
contraceptives, non-chemical; surgical implants; orthopedic
articles; suture materials; furniture especially made for
medical purposes; medical apparatus and instruments. Processing of medicinal materials; processing and handling
of chemical reagents.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Surgical and topical anaesthetics; analgesics; antipyretics; non-steroidal anti-inflammatory medicines; medicines used to treat gout; medicines used to treat disease modifying agents in rheumatoid disorders;antiallergics; medicine used in anaphylaxis; antidotes to counteract poisons; anticonvulsants; anti-epileptics; anti-infectives; anti-migraine medicine; anti-neoplastic; immunosuppressives used in palliative care; pharmaceutical preparations for the treatment of the central nervous system, namely, encephalitis, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease; herbal supplements and pharmaceutical preparations for the treatment of cardiovascular diseases; pharmaceutical preparations for use in dermatology, namely, dermatitis, skin pigmentation diseases, sexually transmitted diseases; pharmaceutical preparations for the treatment of genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, inflammatory pelvic diseases; pharmaceutical preparations for the treatment of gastrointestinal diseases; hormones for humans, namely, human growth hormones, hormone replacement therapy preparations; contraceptives, namely, condoms, diaphragms, foams, oral, sponges, spermicides; opthalmological preparations; medicine acting on the respiratory tract; vitamins; minerals; PCR reagent used to test sputum; PCR reagent used in the hepatis; PCR reagent used in respiratory disease; PCR reagent used in venereal disease; PCR reagent used in bacterial disease; chemical preparations used to test blood; chemical preparations used to test sputum; pharmaceutical preparations for the treatment of blood disorders, the treatment of cancer, headaches, headaches, immunologic diseases, namely, autoimmune diseases, immunologic deficiency syndromes, infectious diseases, namely, respiratory infections, eye infections, inflammatory diseases, namely, inflammatory bowel diseases, inflammatory connective tissue diseases, psychiatric diseases, namely, mood disorders, anxiety disorders, cognitive disorders, the musculoskeletal system, namely, connective tissue disorders, bone diseases, spinal diseases, back pain, fractures, sprains, cartilage injuries, the respiratory system; pharmaceutical preparations for use in gastroenterology.
