Abstract

Weissella confusaWeissella cibariaLactobacillus sakeiLeuconostoc mesenteroidesStreptococcus mutansCandida albicansCandida albicans, and the like, and thus can be effectively used as an anti-biofilm composition and a composition for preventing or treating oral diseases.

IPC Classes  ?

• A61K 35/744 - Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
• A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
• A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
• A61P 31/04 - Antibacterial agents
• A61P 31/10 - Antimycotics
• A23L 29/00 - Foods or foodstuffs containing additivesPreparation or treatment thereof
• A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics

Goods & Services

Processed sweet potatoes; Dried kelps; Edible shavings of dried kelp (tororo-kombu); Processed eggs; Processed, edible seaweed; Beef stew; Pickled fruits; Fruit spreads; Jams; Toasted laver; Laver-based snack foods; Kimchi; Cooked dish consisting primarily of fermented vegetable, pork and tofu (kimchi-jjigae); Frozen vegetables; Stew; Soups; Processed beans; Tofu; Bean curd; Galbi (grilled meat dish); Anchovy, not live; Processed anchovies; Salted and fermented seafood (jeotgal); Prepared side dishes consisting primarily of vegetables; Fermented vegetables; Silkworm chrysalis, for human consumption; Bacon; Bottled vegetables; Preserved, frozen, dried and cooked fruits and vegetables; Fish, not live; Shellfish, not live; Cooked dish consisting primarily of chicken and ginseng (samgyetang); Sausages; Jellies for food, other than confectionery; Sesame oil for food; Eggs; Edible oils and fats; Meat; Fish cakes; Prepared and prepackaged meals and entrees consisting primarily of egg with one or more of meat, fish, poultry, vegetable, cheese or onion; Yogurt; Vegetable juices for cooking; Cream, being dairy products; Milk; Prepared meat; Jerky; Seasoned laver (Jaban-gim); Tuna fish, not live; Dried vegetables; Pickled vegetables; Vegetable salads; Chicken balls; Fish croquettes; Chicken croquettes; Ham; Grilled meat marinated in soy sauce; Non-alcoholic fruit extracts for use as ingredients of nutritional supplements and vitamins Minced garlic; Macaroni and cheese; Soy sauce; Fermented hot pepper paste (gochujang); Hot pepper powder; Cereal-based snack food; Processed grains, namely, flour, oats, flax seeds, quinoa, rice, millet, bulgur, and barley; Fructose for food; Confectionery made of sugar; Noodles; Buckwheat noodles; Crust of overcooked rice (nurungji); Instant rice; Breakfast cereals; Soybean paste; Rice cakes; Instant noodles; Mayonnaise; Korean-style dumplings (mandu); Wheat flour; Stir-fried rice; Bread and buns; Salad dressings; Sugar; Somen noodles; Fruit sauces; Sauces for barbecued meat; Cooked dish consisting primarily of dough flakes with broth (sujebi); Spaghetti; Cereal-based snack bars; Flour for food; Malt for food purposes; Starch syrup for culinary purposes; Edible salt; Starch for food; Vinegar; Ice cream; Chinese rice noodles; Meat tenderizers for culinary purposes; Udon noodles; Seasonings; Tea; Tea-based beverages; Natural sweeteners; Curry powder; Curry pastes; Coffee; Ketchup; Pasta; Pizzas; Hot dog sandwiches; Spices; Pastry; Pepper powder; Sauces; Fish sauce; Sauce mixes; Marinade mixes; Cooking sauces Fruit juices; Vegetable juice; Mineral water; Bottled water; Drinking water; Lemonades; Beer; Extracts of hops for making beer; Preparations for making non-alcoholic carbonated beverages; Non-alcoholic fruit juice beverages; Drinking waters; Soft drinks, namely, sodas; Soda pops; Smoothies; Non-alcoholic fruit vinegar beverages; Non-alcoholic rice punch (sikhye); Powders for making fruit-based beverages; Vegetable-based beverages; Fruit-based beverages; Non-alcoholic vegetable juice beverages; Non-carbonated soft drinks; Aerated water; Energy drinks; Non-alcoholic beverages containing red ginseng juice; Carbonated drinks, non-alcoholic

Abstract

Flavonifractor plautiiFlavonifractor plautiiFlavonifractor plautii or a D-allulose epimerase variant W29K/A77S/G216S/M234I. Therefore, the novel allulose epimerase variant according to the present invention can shorten production time and reduce production costs in an enzyme conversion reaction at an industrial scale for mass production of allulose.

IPC Classes  ?

• C12N 9/90 - Isomerases (5.)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 19/02 - Monosaccharides

Abstract

The present invention relates to: a starch-based biodegradable resin composition having improved odor, water leaching, and mechanical strength as a result of simultaneously using an essential oil masking agent and a compatibilizer that reacts with a hydroxy group of starch; and a biodegradable film using same.

IPC Classes  ?

• C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
• C08L 3/02 - StarchDegradation products thereof, e.g. dextrin
• C08L 75/00 - Compositions of polyureas or polyurethanesCompositions of derivatives of such polymers
• C08K 5/1515 - Three-membered rings
• C08L 9/00 - Compositions of homopolymers or copolymers of conjugated diene hydrocarbons
• C08K 5/5435 - Silicon-containing compounds containing oxygen containing oxygen in a ring
• C08K 5/1539 - Cyclic anhydrides
• C08K 5/151 - Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
• C08K 5/132 - Phenols containing keto groups
• C08K 11/00 - Use of ingredients of unknown constitution, e.g. undefined reaction products

Abstract

The present invention relates to a method for producing 1,4-butanediol using a 1,4-butanediol-producing microorganism. The method for producing 1,4-butanediol can efficiently produce 1,4-butanediol by culturing a microorganism that produces 1,4-butanediol from glutamic acid under optimal medium conditions.

IPC Classes  ?

• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 15/52 - Genes encoding for enzymes or proenzymes
• C12N 9/88 - Lyases (4.)
• C12N 9/10 - Transferases (2.)
• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

Goods & Services

(1) Processed sweet potatoes, namely, blanched and fried sweet potatoes; kelps, dried; edible shavings of dried kelp (tororo-kombu); egg substitutes; egg-based prepared meals; egg salad; processed seaweed; seaweed extracts for food; beef stew; fruit paste; fruit jam; fruit jelly spreads; pickled fruits; toasted laver; laver-based snack foods; kimchi [fermented vegetable dish]; cooked dish consisting primarily of fermented vegetable, pork and tofu [kimchi-jjigae]; frozen vegetables; peeled garlic; preserved garlic; cooked dish consisting primarily of soybean paste and tofu [doenjang-jjigae]; bean-based snack foods; processed legumes; tofu; bean curd; fermented bean curd; dried bean curd; bean curd sticks; grilled meat dish [galbi]; chopped meat patties; anchovy; anchovy fillets; anchovy paste; vegetable side dishes; fermented vegetables; silkworm chrysalis for human consumption; bacon; bottled vegetables; preserved, frozen, and dried fruits and vegetables; fish; shellfish; cooked dish consisting primarily of chicken and ginseng [samgyetang]; sausages; soups; jellies for food, other than confectionery; sesame oil for food; eggs; edible oils and edible fats; meat; fish cakes; prepared and packaged meals consisting primarily of seafood; yogurt; vegetable juices for cooking; dairy products; milk and milk products; salami; prepared meat; preserved meat; packaged meats; jerky; seasoned laver [Jaban-gim]; jams; tuna fish; dried vegetables; pickled vegetables; vegetable salads; cheese; chicken balls; croquettes; edible seaweed; ham. (2) Soy sauce; fermented hot pepper paste [gochujang]; hot pepper powder; cereal-based snack foods; processed grains, namely flour, oats, flax seeds, quinoa, rice, millet, bulgur, and barley; fructose for food; sugar confectionery; noodles; buckwheat noodles; nurungji; instant rice; breakfast cereals; soya bean paste condiment; rice cakes; cooked dish consisting primarily of stir-fried rice cake with fermented hot pepper paste [topokki]; instant noodles; mayonnaise; Korean-style dumplings (Mandu); wheat flour; stir-fried rice; bread; salad dressings; sugar; somen noodles; fruit sauces, vegetable sauces, sauces for meat, seafood sauces; cooked dish consisting primarily of dough flakes with broth [sujebi]; spaghetti; cereal-based bars; flour for food; malt for human consumption; starch syrup for food; edible salt; starch for food; vinegar; ice cream; Chinese rice noodles; meat tenderizers for culinary purposes; fructo-oligosaccharide for culinary purposes; udon noodles; seasonings; tea; tea-based beverages; natural sweeteners; curry powder; curry paste; coffee; ketchup; pasta; pizzas; hot dog sandwiches; spices; pastry; pepper powder; jeotgal. (3) Fruit and vegetable juices; mineral enhanced water; lemonades; beer; extracts of hops for use in making beer; powders for effervescing beverages; non-alcoholic fruit extracts; non-alcoholic fruit juice beverages; drinking waters; soft drink; soda pop; smoothies; non-alcoholic vinegar-based beverages; non-alcoholic rice punch (Sikhye); essences for making non-alcoholic beverages; powders for making soft drinks; non-alcoholic fruit drinks in powder form; vegetable-based beverages; fruit-based beverages; non-alcoholic vegetable juice beverages; non carbonated soft drinks; aerated water; energy drinks; red ginseng juice beverages being ginseng ale; carbonated soft drinks.

Goods & Services

Processed sweet potatoes; kelp, processed; processed brown seaweed; food products consisting primarily of fruit; toasted laver; laver-based snack foods; kimchi; kimchi jjigae [Korean dish consisting primarily of fermented vegetables, pork and tofu]; frozen beans; minced garlic, preserved; cooked dish consisting primarily of soybean paste and tofu (doenjang-jjigae); bean-based foodstuffs made from processed beans (excluding bean curds and foodstuffs made from bean curds); tofu; foods prepared from bean curds (tofu); grilled short rib patties; anchovy, salted, fermented and preserved in liquid; food products consisting primarily of fermented vegetable; food products made from worm; bacon; bottled vegetables; preserved, frozen, dried and cooked fruits and vegetables; fish and shellfish, not live, for food; samgyetang [Korean ginseng chicken soup]; soups; jellies for food; sesame oil for food; edible eggs; oils and fats for food; meat; fish cakes; food products made from fish and shellfish; vegetable juices for cooking; processed dairy products; milk products; processed meat products; jerky; seasoned laver (jaban-gim); jams; salted and fermented seafood (jeotgal); food products consisting primarily of vegetable; vegetable salads; croquettes; processed seaweed products; ham. Soya sauce; gochujang; hot pepper powder [spice]; cereal-based processed products; flour and preparations made from cereals; confectionery; noodles; Korean buckwheat noodles (naeng-myun); nurungji [scorched rice crust]; packed boiled rice; polished cereals; doenjang [condiment]; rice cakes; cooked dish consisting primarily of stir-fried rice cake with fermented hot pepper paste (topokki); instant noodles; mayonnaise; korean-style dumplings (mandu); wheat flour; stir-fried rice; bread; dressings for salad; sugar; sauces; spaghetti; cereal bars; meal; malt for human consumption; starch syrup for food; edible salt; starch for food; vinegar; fructose for food; seasoned bean paste; ice cream; Chinese noodles; meat tenderizers for culinary purposes; oligosaccharides for culinary purposes; seasonings; tea; tea-based beverages; natural sweeteners; curry [spice]; coffee; ketchup [sauce]; pasta; pizzas; hot dogs (sausages in a bread roll); spices; peppers [seasonings]. Beer; extracts of hops for making beer; powders for effervescing beverages; non-alcoholic beverages; waters [beverages]; soda drinks; non-alcoholic beverages, namely, beverages made from vinegar; powders for making fruit-based beverages; vegetable-based beverages and fruit-based beverages, non-alcoholic; aerated water.

Abstract

The present invention relates to: a starch-based biodegradable resin composition having improved color, odor, and mechanical strength as a result of using an essential oil masking agent and a natural crosslinking agent that reacts with a hydroxy group of starch; and a biodegradable film using same.

IPC Classes  ?

• C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
• C08L 3/02 - StarchDegradation products thereof, e.g. dextrin
• C08K 5/00 - Use of organic ingredients
• C08K 5/092 - Polycarboxylic acids
• C08K 3/013 - Fillers, pigments or reinforcing additives
• C08J 5/18 - Manufacture of films or sheets
• C08K 5/151 - Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
• C08K 5/132 - Phenols containing keto groups
• C08K 11/00 - Use of ingredients of unknown constitution, e.g. undefined reaction products

Abstract

The present invention relates to a novel zinc-binding dehydrogenase variant and a method of producing an L-aromatic amino acid using the same. The zinc-binding dehydrogenase variant is obtained by substituting one or more amino acids in the amino acid sequence constituting zinc-binding dehydrogenase to change the enzymatic activity of the zinc-binding dehydrogenase, and a recombinant microorganism comprising the variant is capable of efficiently producing an L-aromatic amino acid.

IPC Classes  ?

• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine
• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli

Abstract

The present invention relates to a food tray by which food such as fried dumplings can be cooked using a cooking appliance such as an air fryer, a microwave oven, or a conventional oven. The food tray according to the present invention includes at least one food accommodation unit. The food accommodation unit includes: a food accommodation space that includes a first side part and a second side part facing each other, a front surface part and a rear surface part respectively connecting the ends of the first side part and the second side part, and a bottom part forming the bottom surface; a central support part including a first central support part and a second central support part that are connected to the first side part and the second side part, respectively, and protrude upward from the bottom part; a front surface support part and a rear surface support part formed, along the longitudinal direction of the food accommodation unit, on the front surface side and the rear surface side, respectively, of the central support part; and a trench part formed on the bottom surface of the food accommodation space.

IPC Classes  ?

• B65D 81/34 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging foodstuffs intended to be cooked or heated within the package
• B65D 1/36 - Trays or like shallow containers with moulded compartments or partitions
• B65D 25/04 - Partitions

Abstract

The present invention relates to: a mutant microorganism with enhanced L-glutamic acid production capability; and a method for producing L-glutamic acid using same. The mutant microorganism has enhanced activities of a sugar permease and a sugar kinase, and thus may have an improved production yield of L-glutamic acid compared to a parent strain.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12P 13/14 - Glutamic acidGlutamine

Abstract

The present invention provides allulose crystal particles exhibiting a particle size distribution in which 80-95 wt% of the total crystal particles have a size of 300 μm or greater and 0.1-5 wt% have a size of less than 212 μm, and having an average aspect ratio (the ratio of major axis length to minor axis length) of 1 to 3 and an average particle size of 400-520 μm. The allulose crystal particles according to the present invention exhibit low hygroscopicity and high anti-caking properties. Accordingly, the allulose crystal particles of the present invention can be stored and distributed for extended periods without degradation in quality.

IPC Classes  ?

• C07H 3/02 - Monosaccharides
• C07H 1/06 - SeparationPurification

Abstract

The present invention provides a method for preparing allulose crystals, comprising the steps of: (a) adding allulose seed crystals to an allulose-containing mother liquor and performing a primary crystallization reaction while a reduced pressure condition of 10-100 mb is maintained and under a temperature gradient condition in which the temperature of the allulose-containing mother liquor is gradually lowered; and (b) releasing the reduced pressure condition when the allulose crystal precipitation rate of the primary crystallization reaction has reached 12% or more, and performing a secondary crystallization reaction while the supersaturated state of the metastable zone is maintained and under a temperature gradient condition in which the temperature of a D-allulose-containing mother liquor is gradually lowered. Allulose crystal particles obtained using the method for preparing allulose crystals, of the present invention, have a large average particle size, are inhibited from caking even if stored for a long time and have low hygroscopicity and excellent flowability. In addition, when the method for preparing allulose crystals, of the present invention, is used, allulose crystallization yield can be improved.

IPC Classes  ?

• C07H 3/02 - Monosaccharides
• C07H 1/06 - SeparationPurification

Abstract

The present invention relates to: a polynucleotide for a novel promoter capable of regulating the expression of a target gene in a microorganism of the genus Corynebacterium; a recombinant vector comprising the polynucleotide; a transformant transformed with the recombinant vector; and a method for producing L-amino acid using the transformant. A polynucleotide having promoter activity according to the present invention can enhance or weaken the expression of a target gene, and can efficiently regulate the production of a target substance through a transformant into which the polynucleotide is introduced, and thus can be effectively used to produce L-amino acids.

IPC Classes  ?

• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/06 - AlanineLeucineIsoleucineSerineHomoserine
• C12P 13/08 - LysineDiaminopimelic acidThreonineValine
• C12P 13/24 - ProlineHydroxyprolineHistidine
• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine
• C12P 13/12 - MethionineCysteineCystine
• C12P 13/20 - Aspartic acidAsparagine
• C12P 13/14 - Glutamic acidGlutamine
• C12P 13/10 - CitrullineArginineOrnithine

Abstract

Provided is a mutant strain having improved aromatic amino acid production capability as a result of inactivation or weakening of activity of glutaminase which is expressed by glutaminase B (glsB) gene.

IPC Classes  ?

• C12N 9/80 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine

Abstract

The present invention relates to a novel variant of pyruvate kinase 2 and a method of producing L-aromatic amino acids using the same. The pyruvate kinase 2 variant is obtained by substituting one or more amino acids in the amino acid sequence constituting pyruvate kinase 2 to change the activity of the protein, and a recombinant microorganism comprising the variant is capable of efficiently producing L-tryptophan, L-phenylalanine, or L-tyrosine.

IPC Classes  ?

• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine
• C12N 1/20 - BacteriaCulture media therefor
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12R 1/15 - Corynebacterium
• C12R 1/19 - Escherichia coli

Abstract

Chlorella protothecoidesChlorella protothecoides; and a method for culturing cells, such as muscle stem cells, using the composition.

IPC Classes  ?

• C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
• C12N 1/12 - Unicellular algaeCulture media therefor
• C12R 1/89 - Algae

Abstract

The present invention relates to a novel variant of DNA-binding transcriptional regulator MalT and a method of producing L-aromatic amino acids using the same. The DNA-binding transcriptional regulator MalT variant is obtained by substituting one or more amino acids in the amino acid sequence constituting DNA-binding transcriptional regulator MalT to change the activity of the protein, and a recombinant microorganism comprising the variant is capable of efficiently producing L-tryptophan, L-phenylalanine, or L-tyrosine.

IPC Classes  ?

• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli

Goods & Services

Chemicals for use in animal nutritional food industry; fertilisers; microorganisms, other than for medical purposes; chemical additives for use in the manufacture of food and beverages; chemical agents for use in the manufacture of dietary supplements; chemical additives for food industry; microalgae for the food industry; amino acid for food industry; artificial sweeteners for the food industry; flavor enhancing preparations for food industry; enzymes for the food industry; chemical additives for use in the manufacture of cosmetics. Air fragrancing preparations; pre-moistened cleansing tissues; cleaning preparations; fabric softeners for laundry use; hand cleansers; room fragrancing preparations; cosmetics for animals; soaps for personal use; toothpaste; cosmetics. Glutamine preparations; nutritional supplements for animal foodstuffs; lysine preparations; mineral food supplements; vitamin preparations; sanitary pads; nutraceuticals for use as a dietary supplement; dietary fiber; starch for dietetic or pharmaceutical purposes; arginine preparations; dietary supplements consisting of amino acids; milk sugar for pharmaceutical purposes; nutritional supplements; babies' diapers; dietary supplements for infants; preparations of microorganisms for medical and veterinary use; cotton for medical purposes; dietetic substances adapted for medical use; amino acid preparations for medical purposes; drugs for medical purposes. Cereal-based processed products; confectionery; malt for human consumption; edible salt; food flavorings, other than essential oils; gluten additives for culinary purposes; seasonings; tea; tea-based beverages; coffee; spices; leaven; food flavoring, being essential oils; food flavorings [essential oils]; flavorings for beverages [essential oils].

Abstract

The present invention relates to a mutant microorganism exhibiting enhanced 1,4-butanediol production capability and a method for producing 1,4-butanediol by using same, wherein attenuation of serine/threonine protein kinase activity in the mutant microorganism enhances the flux of the 1,4-butanediol biosynthetic pathway, thereby enabling efficient production of 1,4-butanediol.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

The present invention relates to a mutant microorganism having enhanced 1,4-butanediol production capability and a method for producing 1,4-butanediol using same. The mutant microorganism attenuates the activities of formaldehyde dehydrogenase, alcohol dehydrogenase A, and acetaldehyde dehydrogenase, which are expected to be involved in a degradation pathway for 1,4-butanediol, thereby inhibiting degradation of 1,4-butanediol and improving the production yield of 1,4-butanediol.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

The present invention relates to a novel carboxylic acid reductase variant and a method for producing 1,4-butanediol using same, wherein the carboxylic acid reductase variant has altered protein activity resulting from substitution of one or more amino acids in the amino acid sequence constituting carboxylic acid reductase, so that a transformant or recombinant microorganism comprising same can efficiently produce the carboxylic acid reductase.

IPC Classes  ?

• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Goods & Services

(1) Processed sweet potatoes; kelp, processed; processed brown seaweed; food products consisting primarily of fruit; toasted laver; laver-based snack foods; kimchi; kimchi jjigae [Korean dish consisting primarily of fermented vegetables, pork and tofu]; frozen beans; minced garlic, preserved; cooked dish consisting primarily of soybean paste and tofu (doenjang-jjigae); bean-based foodstuffs made from processed beans (excluding bean curds and foodstuffs made from bean curds); tofu; foods prepared from bean curds (tofu); grilled short rib patties; anchovy, salted, fermented and preserved in liquid; food products consisting primarily of fermented vegetable; food products made from worm; bacon; bottled vegetables; preserved, frozen, dried and cooked fruits and vegetables; fish and shellfish, not live, for food; samgyetang [Korean ginseng chicken soup]; soups; jellies for food; sesame oil for food; edible eggs; oils and fats for food; meat; fish cakes; food products made from fish and shellfish; vegetable juices for cooking; processed dairy products; milk products; processed meat products; jerky; seasoned laver (jaban-gim); jams; salted and fermented seafood (jeotgal); food products consisting primarily of vegetable; vegetable salads; croquettes; processed seaweed products; ham. (2) Soya sauce; gochujang; hot pepper powder [spice]; cereal-based processed products; flour and preparations made from cereals; confectionery; noodles; Korean buckwheat noodles (naeng-myun); nurungji [scorched rice crust]; packed boiled rice; polished cereals; doenjang [condiment]; rice cakes; cooked dish consisting primarily of stir-fried rice cake with fermented hot pepper paste (topokki); instant noodles; mayonnaise; korean-style dumplings (mandu); wheat flour; stir-fried rice; bread; dressings for salad; sugar; sauces; spaghetti; cereal bars; meal; malt for human consumption; starch syrup for food; edible salt; starch for food; vinegar; fructose for food; seasoned bean paste; ice cream; Chinese noodles; meat tenderizers for culinary purposes; oligosaccharides for culinary purposes; seasonings; tea; tea-based beverages; natural sweeteners; curry [spice]; coffee; ketchup [sauce]; pasta; pizzas; hot dogs (sausages in a bread roll); spices; peppers [seasonings]. (3) Beer; extracts of hops for making beer; powders for effervescing beverages; non-alcoholic beverages; waters [beverages]; soda drinks; non-alcoholic beverages, namely, beverages made from vinegar; powders for making fruit-based beverages; vegetable-based beverages and fruit-based beverages, non-alcoholic; aerated water.

Goods & Services

Processed eggs; processed vegetables; vegetable and seaweed laver chips; kimchi spreads; kimchi; foods prepared from bean curds (tofu); fermented vegetable foods; food products made from worm; preserved, frozen, dried and cooked fruits and vegetables; fish-based foodstuffs; soups; oils and fats for food; jellies for food; processed dairy products; processed meat products; jams; processed seaweed products. Gochujang; hot pepper powder [spice]; cereal-based processed products; kimchi seasonings; polished cereals; rice cakes; cooked dish consisting primarily of stir-fried rice cake with fermented hot pepper paste (Topokki); instant noodles; mandu [Korean-style dumplings]; bibimbap [rice mixed with vegetables and beef]; bread; sauces; edible salt; starch for food; seasonings; tea; tea-based beverages; natural sweeteners; coffee; spices.

Abstract

Caldibacillus debilisCaldibacillus debilis strain, and exhibits a very high conversion activity of glucose to fructose and excellent thermal stability. Therefore, when the method for preparing fructose, according to one embodiment of the present invention, is used, fructose can be prepared in a high yield from glucose. The xylose isomerase used in the method for preparing fructose, according to one embodiment of the present invention, has excellent thermal stability, and thus enables fructose to be continuously prepared for a long period of time.

IPC Classes  ?

• C12P 19/24 - Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
• C12P 19/02 - Monosaccharides
• C12N 9/92 - Glucose isomerase

Abstract

The present invention relates to a novel amino acid derivative and a method for preparing same. In the method for preparing an amino acid derivative, various substituents can be introduced through a simple chemical reaction.

IPC Classes  ?

• C07C 237/16 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated
• C07C 231/12 - Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
• C07C 237/06 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Abstract

The present invention relates to a novel amino acid derivative and a method for preparing same and, to a method for preparing an amino acid derivative, being capable of introducing various substituents through a simple chemical reaction.

IPC Classes  ?

• C07C 237/16 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated
• C07C 231/12 - Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
• C07C 237/06 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Goods & Services

(1) Chemicals for use in animal nutritional food industry; fertilisers; microorganisms, other than for medical purposes; chemical additives for use in the manufacture of food and beverages; chemical agents for use in the manufacture of dietary supplements; chemical additives for food industry; microalgae for the food industry; amino acid for food industry; artificial sweeteners for the food industry; flavor enhancing preparations for food industry; enzymes for the food industry; chemical additives for use in the manufacture of cosmetics. (2) Air fragrancing preparations; pre-moistened cleansing tissues; cleaning preparations; fabric softeners for laundry use; hand cleansers; room fragrancing preparations; cosmetics for animals; soaps for personal use; toothpaste; cosmetics. (3) Glutamine preparations; nutritional supplements for animal foodstuffs; lysine preparations; mineral food supplements; vitamin preparations; sanitary pads; nutraceuticals for use as a dietary supplement; dietary fiber; starch for dietetic or pharmaceutical purposes; arginine preparations; dietary supplements consisting of amino acids; milk sugar for pharmaceutical purposes; nutritional supplements; babies' diapers; dietary supplements for infants; preparations of microorganisms for medical and veterinary use; cotton for medical purposes; dietetic substances adapted for medical use; amino acid preparations for medical purposes; drugs for medical purposes. (4) Cereal-based processed products; confectionery; malt for human consumption; edible salt; food flavorings, other than essential oils; gluten additives for culinary purposes; seasonings; tea; tea-based beverages; coffee; spices; leaven; food flavoring, being essential oils; food flavorings [essential oils]; flavorings for beverages [essential oils].

Goods & Services

Glutamine preparations; nutritional supplements for animal foodstuffs; lysine preparations; mineral food supplements; vitamin preparations; sanitary pads; nutraceuticals for use as a dietary supplement; dietary fiber; starch for dietetic or pharmaceutical purposes; arginine preparations; dietary supplements consisting of amino acids; milk sugar for pharmaceutical purposes; nutritional supplements; babies' diapers; dietary supplements for infants; preparations of microorganisms for medical and veterinary use; cotton for medical purposes; dietetic substances adapted for medical use; amino acid preparations for medical purposes; drugs for medical purposes

Abstract

The present disclosure relates to a Corynebacterium sp. mutant strain having increased L-arginine or L-citrulline productivity and a method of producing L-arginine or L-citrulline using the same. The Corynebacterium sp. mutant strain has enhanced activity of acetylglutamate kinase involved in the L-arginine biosynthesis pathway, and thus is capable of producing L-arginine or L-citrulline in an increased yield compared to a parent strain.

IPC Classes  ?

• C12N 1/20 - BacteriaCulture media therefor
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a gene variant of the transcriptional regulator LysG and a method for producing L-citrulline or L-arginine using same. The gene variant of the transcriptional regulator LysG according to the present invention has protein activity that is altered due to the mutation of one or more bases in the base sequence of a gene encoding the transcriptional regulator LysG, and thus, it is possible to effectively produce L-citrulline or L-arginine from a recombinant microorganism comprising the variant.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/10 - CitrullineArginineOrnithine

Goods & Services

Kimchi; Fermented vegetables; Fermented fruits; Pickled vegetables; Pickled fruits; Processed vegetables and fruits

Goods & Services

Sauces; Seasonings; Savory sauces used as condiments

Abstract

The present invention relates to a Corynebacterium sp. mutant microorganism producing L-glutamic acid and a method of producing L-glutamic acid using the same, and more specifically, to a novel oxidoreductase variant involved in the L-glutamic acid biosynthetic pathway, a polynucleotide, and a transformant, as well as a method of producing L-glutamic acid using the same. The oxidoreductase variant according to the present invention is obtained by substituting one or more amino acids in the amino acid sequence constituting oxidoreductase to change the enzymatic activity of the oxidoreductase, and a recombinant microorganism comprising the oxidoreductase variant is capable of efficiently producing L-glutamic acid.

IPC Classes  ?

• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 1/20 - BacteriaCulture media therefor
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/14 - Glutamic acidGlutamine
• C12R 1/28 - Micrococcus glutamicus

Abstract

The present invention relates to a Corynebacterium sp. mutant microorganism producing L-glutamic acid and a method of producing L-glutamic acid using the same, and more specifically, to a novel NADP-dependent malic enzyme variant involved in the L-glutamic acid biosynthetic pathway, a polynucleotide, and a transformant, as well as a method of producing L-glutamic acid using the same. The NADP-dependent malic enzyme variant according to the present invention is obtained by substituting one or more amino acids in the amino acid sequence constituting NADP-dependent malic enzyme to change the enzymatic activity of the NADP-dependent malic enzyme, and a recombinant microorganism comprising the NADP-dependent malic enzyme variant is capable of efficiently producing L-glutamic acid.

IPC Classes  ?

• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
• C12N 1/20 - BacteriaCulture media therefor
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/14 - Glutamic acidGlutamine
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to an Escherichia microorganism with improved L-isoleucine productivity and a method for producing L-isoleucine using same, the Escherichia microorganism having reduced or deactivated acetohydroxy acid synthases I and III activity but stronger acetohydroxy acid synthase II activity to thus strengthen L-isoleucine biosynthesis pathways and reduce production of by-products, thereby allowing the L-isoleucine production level to be greater than that with the parent strain.

IPC Classes  ?

• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 9/10 - Transferases (2.)
• C12P 13/06 - AlanineLeucineIsoleucineSerineHomoserine
• C12R 1/19 - Escherichia coli

Abstract

The present invention relates to microorganisms of the Brevibacterium spp. or Corynebacterium spp. having improved L-isoleucine productivity and a method for producing L-isoleucine using same, the activities of endogenous acetolactate synthase being reduced or deactivated while the activity of exogenous acetolactate synthase II is strengthened to allow the L-isoleucine production level, with reduced by-product production, to be greater than that with the mother strain.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/10 - Transferases (2.)
• C12P 13/06 - AlanineLeucineIsoleucineSerineHomoserine
• C12R 1/13 - Brevibacterium
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a microorganism of the genus Corynebacterium with improved L-citrulline or L-arginine productivity and a method for producing L-citrulline or L-arginine using same. The microorganism of the genus Corynebacterium can improve the production yield of L-citrulline or L-arginine compared to pre-mutation, due to strengthened activity of glutamine synthase, aspartate aminotransferase and carbamoyl phosphate synthase.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C12N 9/10 - Transferases (2.)
• C12N 15/52 - Genes encoding for enzymes or proenzymes
• C12P 13/10 - CitrullineArginineOrnithine
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to an Escherichia microorganism with improved L-isoleucine productivity and a method for producing L-isoleucine using same, the Escherichia microorganism having reduced or deactivated threonine operon leader peptide and threonine dehydrogenase activity to thus strengthen L-isoleucine biosynthesis pathways and reduce production of by-products, thereby allowing the L-isoleucine production level to be greater than that with the parent strain.

IPC Classes  ?

• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/06 - AlanineLeucineIsoleucineSerineHomoserine
• C07K 14/245 - Escherichia (G)

Goods & Services

Processed sweet potatoes; kelp, processed; processed eggs; processed brown seaweed; short rib soup (galbi tang); food products consisting principally of fruit; toasted laver; laver-based snack foods; kimchi; kimchi jjigae [Korean dish consisting primarily of fermented vegetables, pork and tofu]; frozen beans; minced garlic, preserved; doenjang jjigae [Korean dish consisting primarily of tofu with soybean paste]; processed beans, namely, bean-based foods excluding bean curds and foodstuffs made from bean curds; tofu; foods prepared from bean curds (tofu); grilled short rib patties; anchovy, salted, fermented and preserved in liquid; prepared side dishes consisting primarily of meat, fish, poultry or vegetable; food products consisting principally of fermented vegetable; silkworm chrysalis for human consumption; bacon; bottled vegetables; preserved, frozen, dried and cooked fruits and vegetables; fish and shellfish, not live, for food; samgyetang [Korean ginseng chicken soup]; sausages; soups; jellies for food; sesame oil for food; edible eggs; edible oils and fats; meat; fish cakes; food products made from fish and shellfish; yogurt; vegetable juices for cooking; processed dairy products; milk products; processed meat products; jerky; seasoned laver (jaban-gim); jams; tuna, not live; food products consisting principally of vegetable; vegetable salads; cheese; chicken balls; croquettes; processed edible seaweed products; ham. Soya sauce; fermented hot pepper paste (gochujang); hot pepper powder [spice]; cereal-based processed products; flour and preparations made from cereals; fructose for food; confectionery; noodles; Korean buckwheat noodles (naeng-myun); nurungji [scorched rice crust]; instant rice; polished cereals; soybean paste being seasoning; rice cakes; cooked dish consisting primarily of stir-fried rice cake with fermented hot pepper paste (topokki); instant noodles; mayonnaise; Korean-style dumplings (mandu); wheat flour; stir-fried rice; bread; salad dressings; sugar; somen noodles; sauces; cooked dish consisting primarily of dough flakes with broth (sujebi); spaghetti; cereal bars; flour for food; malt for human consumption; starch syrup for food; edible salt; starch for food; vinegar; ice cream; Chinese noodles; meat tenderizers for culinary purposes; oligosaccharides for culinary purposes; udon noodles; seasonings; tea; tea-based beverages; natural sweeteners; fermented soybean paste being seasoning; curry [spice]; coffee; ketchup [sauce]; pasta; pizzas; hot dogs (sandwiches); spices; small walnut-flavored cake in the size and shape of a walnut; pepper powder [spice]; Korean condiment made from salted and fermented seafood (jeotgal). Fruit juices; mineral water; lemonades; beer; extracts of hops for making beer; powders for effervescing beverages; non-alcoholic fruit extracts; non-alcoholic beverages; waters [beverages]; soda drinks; smoothies; non-alcoholic beverages, namely, beverages made from vinegar; non-alcoholic rice punch (sikhye); powders for making fruit-based beverages; vegetable-based beverages and fruit-based beverages; non-alcoholic vegetable juice beverages; soft drinks, non-carbonated; aerated water; red ginseng drinks.

Goods & Services

Preserved, frozen, dried and cooked fruits and vegetables; soups; jellies for food; meat; frozen beans; frozen garlic; processed fruit foods; processed vegetable foods; jams; kimchi; fruit-based snack food; bottled vegetables; fermented vegetable foods; preserved onions; Korean sliced vegetables preserved in soy sauce or soybean paste (jangajji); gherkins; preserved vegetables, other than those frozen; vegetable soups; vegetable salads; Korean pickled mustard leaves and stems (gatkimchi); cucumber kimchi [oi-sobagi]; minced garlic, preserved; kimchi jjigae [Korean dish consisting primarily of fermented vegetables, pork and tofu]; doenjang jjigae [Korean dish consisting primarily of tofu with soybean paste]; kimchi made of perilla leaf; kimchi made of crepidiastrum sonchifolium; cubed radish kimchi (kkakdugi); prepared peanuts; vegetable juices for cooking; foods prepared from bean curds (tofu); tofu; Korean-style fermented soybeans (meju); food products made from beans (excluding bean curds and foodstuffs made from bean curds); beans cooked in soy sauce (kongjaban); frozen fruits; eggs; edible eggs; processed meat products; ham; sausages; pork cutlets; grilled short rib patties; chicken ball; bacon; bouillon; dried beef; samgyetang [Korean ginseng chicken soup]; meat boiled down in soy sauce; spicy beef broth (yukgaejang); short rib soup (galbi tang); milk products; processed dairy products; cheese; yogurt; edible oils and fats; food products made from oil and fat; sesame oil for food; silkworm chrysalis for human consumption; fish and shellfish, not live, for food; processed edible seaweed products; laver-based snack foods; processed brown seaweed; toasted laver; processed sea tangle; processed green laver; seasoned laver (jaban-gim); food products made from fish and shellfish; fish cutlet; fish sausages; smoked fish and shellfish; fish cakes; tuna, canned; loach soup; liquid salted and fermented anchovy; liquid salted and fermented sand eel. Seasonings; polished cereals; flour for food; starch for food; wheat flour; frying flour; capers; cereal-based processed products; Korean-style dumplings (mandu); cooked dish consisting primarily of stir-fried rice cake with fermented hot pepper paste (topokki); noodles; spaghetti; Chinese noodles; udon noodles; Korean buckwheat noodles (naeng-myun); instant noodles; pizzas; hot dogs (sausages in a bread roll); processed cereals; nurungji [scorched rice crust]; noodles with black soybean sauce (jajangmyeon); pasta; somen noodles; dried noodles; buckwheat noodles; cooked dish consisting primarily of dough flakes with broth (sujebi); buckwheat noodles (makguksu); malt for human consumption; natural sweeteners; starch syrup for food; sugar; fructose; oligosaccharides for culinary purposes; rice cakes; injeolmi [glutinous rice cakes coated with powdered beans]; rice cakes for stir-fried rice cake; rice cakes (joraengi); stick of rounded rice cakes (garaetteok); fermented hot pepper paste (gochujang); doenjang (soybean paste); seasoned bean paste for use as a condiment; ja-jang (black soybean sauce); Chinese soybean paste (chun-jang); soya sauce; fermented soybean paste (chonggug-jang); sauces; vinegar; dressings for salad; mayonnaise; ketchup [sauce]; spices; hot pepper powder [spice]; curry [spice]; mustard meal; pepper powder [spice]; ground ginger; wasabi powder [Japanese horseradish]; minced garlic [condiment]; edible salt; tea; barley tea; corn tea; coffee; tea-based beverages; edible ices; confectionery; ice cream; bread; Korean condiment made from salted and fermented seafood (jeotgal).

Abstract

The present invention relates to a microorganism of the genus Corynebacterium with an improved ability to produce L-lysine and a method for producing L-lysine, using same. The microorganism of the genus Corynebacterium exhibits enhanced activities of a glucose-facilitated diffusion transporter and glucokinase, and thus can have improved L-lysine production yield as compared to a parent strain or cases where a glucose-facilitated diffusion transporter or glucokinase is enhanced alone.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C07K 14/195 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria
• C12P 13/08 - LysineDiaminopimelic acidThreonineValine

Goods & Services

Processed eggs; Nut-based snack foods; Meat-based snack food; Fruit salads; Fruit-based snack food; Toasted laver; seaweed bugak; Laver bugak, namely, seaweed chips; Seaweed-based snacks; Frozen vegetables; Frozen fruits; processed beans, namely, foodstuffs made from beans excluding bean curds and foodstuffs made from bean curds; Tofu-based snacks; food products made from worm, namely, silkworm chrysalis for human consumption ; Laver, preserved; Processed fish; Edible oils and fats; dairy products, namely, dairy-based food beverages, dairy-based dips, cream being dairy products, dairy-based spreads; Processed meat; Seasoned laver (Jaban-gim); Vegetable-based snack food; Processed, edible seaweed; Dried edible seaweed; dried flakes of laver for sprinkling on rice in hot water (ochazuke-nori) (Based on 44(d) Priority Application)(Based on Intent to Use) Soy sauce; Processed grains; Grain-based snack foods; Cookies; noodles; Prepared roll with vegetable and noodles wrapped in seaweed (Gimmari); Prepared noodles rolled in seaweed; fried noodles wrapped in seaweed; Kimbap; (Based on Intent to Use) seaweed fritter; Fried dough cookies; Fried rice chips

Abstract

The present invention relates to a novel phosphoenolpyruvate carboxylase variant and a method of producing 5′-inosinic acid using the same. The phosphoenolpyruvate carboxylase variant is obtained by substituting one or more amino acids in the amino acid sequence constituting phosphoenolpyruvate carboxylase to change the activity of the protein, and a recombinant microorganism comprising the phosphoenolpyruvate carboxylase variant is capable of efficiently producing 5′-inosinic acid.

IPC Classes  ?

• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
• C12N 9/88 - Lyases (4.)

Abstract

The present invention relates to a novel PTS transporter subunit EIIC variant and a method of producing 5′-inosinic acid using the same. The PTS transporter subunit EIIC variant is obtained by substituting one or more amino acids in the amino acid sequence constituting PTS transporter subunit EIIC to change the activity of the protein, and a recombinant microorganism comprising the PTS transporter subunit EIIC variant is capable of efficiently producing 5′-inosinic acid.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

Corynebacterium sp. mutant microorganism producing L-glutamic acid and a method of producing L-glutamic acid using the same, and more specifically, to a novel biotin-protein ligase variant involved in the L-glutamic acid biosynthetic pathway, a polynucleotide, and a transformant, as well as a method of producing L-glutamic acid using the same. The biotin-protein ligase variant according to the present invention is obtained by substituting one or more amino acids in the amino acid sequence constituting biotin-protein ligase to change the enzymatic activity of the biotin-protein ligase, and a recombinant microorganism comprising the biotin-protein ligase variant is capable of efficiently producing L-glutamic acid.

IPC Classes  ?

• C12P 13/18 - Glutamic acidGlutamine using biotin or its derivatives
• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium

Abstract

Corynebacterium sp. mutant microorganism producing L-glutamic acid and a method of producing L-glutamic acid using the same, and more specifically, to a novel nicotinamide mononucleotide transporter variant involved in the L-glutamic acid biosynthetic pathway, a polynucleotide, and a transformant, as well as a method of producing L-glutamic acid using the same. The nicotinamide mononucleotide transporter variant according to the present invention is obtained by substituting one or more amino acids in the amino acid sequence constituting nicotinamide mononucleotide transporter to change the enzymatic activity of the nicotinamide mononucleotide transporter, and a recombinant microorganism comprising the nicotinamide mononucleotide transporter variant is capable of efficiently producing L-glutamic acid.

IPC Classes  ?

• C12P 13/14 - Glutamic acidGlutamine
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium

Abstract

The present invention relates to a novel 5-dehydro-2-deoxygluconokinase variant and a method of producing 5′-inosinic acid using the same. The 5-dehydro-2-deoxygluconokinase variant is obtained by substituting one or more amino acids in the amino acid sequence constituting 5-dehydro-2-deoxygluconokinase to change the activity of the protein, and a recombinant microorganism comprising the 5-dehydro-2-deoxygluconokinase variant is capable of efficiently producing 5′-inosinic acid.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to: a mutant microorganism having improved L-citrulline or L-arginine productivity; and a method for producing L-citrulline or L-arginine using same. The mutant microorganism can improve the production yield of L-citrulline or L-arginine compared to the parent strain by weakening or inactivating the activity of a protein encoded by the NCgl2653 gene.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/10 - CitrullineArginineOrnithine
• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)

Goods & Services

Ramen; Instant noodles

Goods & Services

Ramen; Instant noodles

Abstract

The present invention relates to a method for preparing a seasoning material using a process of mixing two or more species of microbes that produce products different from each other and fermenting the microbes at the same time. In the method for preparing a seasoning material, heterogeneous microbes that produce different products, that is, different amino acids, nucleic acids, and/or organic acids, are mixed and fermented, thereby enabling the preparation of the seasoning material that increases the taste and flavor of foods through a fermented solution containing the amino acids, nucleic acids, and/or organic acids and which improves overall sensory properties of foods. Such a seasoning material can find applications in the various food fields.

IPC Classes  ?

• A23L 27/22 - Synthetic spices, flavouring agents or condiments containing amino acids containing glutamic acids
• A23L 27/23 - Synthetic spices, flavouring agents or condiments containing nucleotides
• A23L 27/24 - Synthetic spices, flavouring agents or condiments prepared by fermentation

Abstract

The present invention relates to a mutant microorganism with an enhanced ability to produce nicotinamide mononucleotide and a method for producing nicotinamide mononucleotide, using same. The mutant microorganism can produce nicotinamide mononucleotide with a high yield by enhancing, weakening or inhibiting the expression of enzymes, such as nicotinate phosphoribosyltransferase, involved in nicotinamide mononucleotide production pathways.

IPC Classes  ?

• C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
• C12N 9/10 - Transferases (2.)
• C12N 9/80 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12P 19/30 - Nucleotides

Abstract

One example of the present invention provides a promoter which comprises a base sequence of SEQ ID NO: 6 or a base sequence of SEQ ID NO: 27 and which regulates the expression of allulose epimerase in Corynebacterium sp. strain. The novel promoter according to the present invention can constitutively express, at a high level, a target protein, particularly an enzyme, in a Corynebacterium sp. strain. For example, by using a recombinant Corynebacterium sp. strain. that has been transformed using an expression vector comprising the novel promoter according to the present invention, allulose epimerase can be economically mass-produced or allulose can be economically mass-produced from fructose.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/90 - Isomerases (5.)
• C12P 19/02 - Monosaccharides

Abstract

The present invention relates to a starch-based biodegradable composition having excellent mechanical properties and durability and to a biodegradable film prepared using same, the starch-based biodegradable composition comprising a thermoplastic starch, a biodegradable resin, a first compatibilizer, a second compatibilizer, and a lubricant, wherein the first compatibilizer is an epoxy compound, and the second compatibilizer is a tricarboxylic acid.

IPC Classes  ?

• C08L 3/02 - StarchDegradation products thereof, e.g. dextrin
• C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
• C08K 5/09 - Carboxylic acidsMetal salts thereofAnhydrides thereof
• C08K 5/1515 - Three-membered rings
• C08K 5/56 - Organo-metallic compounds, i.e. organic compounds containing a metal-to-carbon bond
• C08J 5/18 - Manufacture of films or sheets
• B29B 9/06 - Making granules by dividing preformed material in the form of filamentary material, e.g. combined with extrusion
• B29C 48/92 - Measuring, controlling or regulating
• B29C 48/88 - Thermal treatment of the stream of extruded material, e.g. cooling
• B29C 48/04 - Particle-shaped

Abstract

The present invention relates to a method for producing fibrous biomass, including a hydration grinding process and a physical treatment process, the method comprising the steps of: pretreating and grinding herbaceous biomass and supplying same to a hydration extruder; supplying, to a disk refiner, the resulting hydrated biomass extrudate that has undergone hydration grinding by the hydration extruder; and physically treating the hydrated biomass extrudate by controlling the solid-to-liquid ratio of the disk refiner. The fibrous biomass produced by the method is suitable for use as a high-strength reinforcing material in a biodegradable resin composition.

IPC Classes  ?

• D01B 9/00 - Other mechanical treatment of natural fibrous or filamentary material to obtain fibres or filaments
• C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08L 97/02 - Lignocellulosic material, e.g. wood, straw or bagasse
• C08L 1/02 - CelluloseModified cellulose
• C08K 7/02 - Fibres or whiskers

Abstract

Mycobacteroides abscessusMassilienseMycobacterium canariasenseMycobacterium conceptionenseMycobacterium conceptionense, and can efficiently produce 1,4-butanediol by expressing carboxylic acid reductase having high substrate activity for 4-hydroxybutyric acid.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

One embodiment of the present invention provides a method for purifying an allulose-containing solution, the method comprising a step of obtaining an ion-purified allulose-containing solution by passing an allulose-containing solution through an ion exchange resin column filled with a mixed-phase ion exchange resin. In the method for purifying an allulose-containing solution according to an embodiment of the present invention, the mixed-phase ion exchange resin is a mixture of a strongly acidic cation exchange resin and a weakly basic anion exchange resin, the weakly basic anion exchange resin constituting the mixed-phase ion exchange resin having an exchange capacity fraction of quaternary ammonium of 0-10%. Using the method for purifying an allulose-containing solution according to the present invention not only enables the electrical conductivity of the allulose-containing solution to be lowered to an acceptable level, but also minimizes the loss of allulose because the conversion of allulose into fructose or other materials due to a functional group of the ion exchange resin can be suppressed. Therefore, the purification method for purifying an allulose-containing solution according to an embodiment of the present invention is suitable for the mass production of high-quality allulose.

IPC Classes  ?

• C07H 3/02 - Monosaccharides
• C07H 1/06 - SeparationPurification
• B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
• C12P 19/02 - Monosaccharides

Abstract

The present invention relates to: a thermoplastic starch composition which has improved melt flow characteristics and processability and comprises a modified starch having a controlled molecular weight due to treatment with an acid; and a biodegradable resin composition and a film which have excellent mechanical properties and comprise the thermoplastic starch composition.

IPC Classes  ?

• C08L 3/10 - Oxidised starch
• C08K 5/09 - Carboxylic acidsMetal salts thereofAnhydrides thereof
• C08K 5/00 - Use of organic ingredients
• C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
• C08J 5/18 - Manufacture of films or sheets

Abstract

The present invention relates to a method for preparing a biodegradable resin composition using an isocyanate compound as a compatibilizing agent, and a biodegradable resin composition and a biodegradable film having, due to the method, a decreased rate of dissolution in water and thus improved durability and mechanical properties.

IPC Classes  ?

• C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
• C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
• C08L 3/02 - StarchDegradation products thereof, e.g. dextrin
• C08K 5/09 - Carboxylic acidsMetal salts thereofAnhydrides thereof
• C08K 5/29 - Compounds containing carbon-to-nitrogen double bonds
• C08K 5/00 - Use of organic ingredients
• C08K 5/053 - Polyhydroxylic alcohols
• C08J 5/18 - Manufacture of films or sheets

Abstract

Corynebacterium glutamicumMycobacterium tuberculosisMycobacterium tuberculosis, and can efficiently produce 1,4-butanediol by expressing phosphopantetheinyl transferase having excellent reactivity with carboxylic acid reductase.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

Arabidopsis thalianaArabidopsis thaliana.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/10 - Transferases (2.)
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

Mycobacteroides abscessusMassilienseMycobacterium canariasenseMycobacterium conceptionenseMycobacterium conceptionense, and can efficiently produce 1,4-butanediol by expressing phosphopantetheinyl transferase having excellent reactivity with carboxylic acid reductase.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

Escherichia coliEscherichia coli, thereby enhancing the supply of pyridoxal 5'-phosphate used as a coenzyme in the 1,4-butanediol production pathway and efficiently producing 1,4-butanediol.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 9/06 - Oxidoreductases (1.), e.g. luciferase acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

An exemplary embodiment of the present disclosure provides an allulose epimerase expression cassette including a polynucleotide encoding allulose epimerase and a promoter which is operably linked thereto and regulates the expression of the allulose epimerase in a Corynebacterium genus strain. The promoter consists of a base sequence represented by SEQ ID NO: 1, a base sequence represented by SEQ ID NO: 9, a base sequence represented by SEQ ID NO: 10, or a base sequence represented by SEQ ID NO: 11. The allulose epimerase expression cassette may be hardly operated under a normal environment of culturing a recombinant Corynebacterium genus strain and does not induce growth inhibition of the recombinant Corynebacterium genus strain. The recombinant Corynebacterium genus strain transformed with the allulose epimerase expression cassette may grow and proliferate normally until a logarithmic phase and stably and highly express allulose epimerase after the logarithmic phase.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/90 - Isomerases (5.)
• C12P 19/02 - Monosaccharides

Abstract

One embodiment of the present disclosure provides a promoter consisting of a base sequence represented by SEQ ID NO: 6 or a base sequence represented by SEQ ID NO: 27 and regulating the expression of allulose epimerase in a Corynebacterium sp. strain. According to the present disclosure, the novel promoter may constitutively and highly express a target protein, particularly an enzyme, in a Corynebacterium sp. strain. For example, by using a recombinant Corynebacterium sp. strain transformed with an expression vector including the novel promoter according to the present disclosure, it is possible to economically mass-produce allulose epimerase or economically mass-produce allulose from fructose.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 1/20 - BacteriaCulture media therefor
• C12N 9/90 - Isomerases (5.)
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a Corynebacterium sp. microorganism having improved L-amino acid productivity and a method for producing L-amino acids using same. The Corynebacterium sp. microorganism can have an improved production yield of L-amino acids, compared to a parent strain, due to weakened activity or inactivity of a carotenoid biosynthesis enzyme.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/10 - CitrullineArginineOrnithine
• C12P 13/08 - LysineDiaminopimelic acidThreonineValine
• C12P 13/14 - Glutamic acidGlutamine

Abstract

The present invention relates to a mutant microorganism with enhanced L-glutamic acid production capability and a method for producing L-glutamic acid using same. The mutant microorganism can exhibit improved production yield of L-glutamic acid compared to the parent strain due to the weakened or inactivated activity of the RamB protein.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)

Abstract

Provided in one embodiment of the present invention is a method for improving the storage stability of a saccharide-containing solution, comprising a step of irradiating a saccharide-containing solution with light-emitting diode (LED) light. Even if a saccharide-containing solution, particularly, an allulose-containing solution, is stored at various temperatures, the method according to one embodiment of the present invention delays browning of the saccharide-containing solution without affecting changes in the pH and saccharide amount of the saccharide-containing solution. In addition, if a browned saccharide-containing solution is stored using the method according to one embodiment of the present invention, the browned saccharide-containing solution can be decolorized.

IPC Classes  ?

• A23B 2/00 - Preservation of foods or foodstuffs, in general
• A23L 29/30 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing carbohydrate syrupsFoods or foodstuffs containing additivesPreparation or treatment thereof containing sugarsFoods or foodstuffs containing additivesPreparation or treatment thereof containing sugar alcohols, e.g. xylitolFoods or foodstuffs containing additivesPreparation or treatment thereof containing starch hydrolysates, e.g. dextrin
• A23L 5/30 - Physical treatment, e.g. electrical or magnetic means, wave energy or irradiation

Abstract

The present invention relates to a novel GlnH protein mutant and a method for producing L-glutamic acid by using same. In the GlnH protein mutant, one or more amino acids from among amino acid sequences constituting a GlnH protein are substituted to change protein activity, and thus L-glutamic acid can be efficiently produced from a recombinant microorganism comprising the mutant.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/14 - Glutamic acidGlutamine

Abstract

The present invention relates to a novel ATP synthase variant and a method of producing an L-aromatic amino acid using the same. The ATP synthase variant is obtained by substituting one or more amino acids in the amino acid sequence constituting ATP synthase to change the enzymatic activity of the ATP synthase, and a recombinant microorganism comprising the ATP synthase variant is capable of efficiently producing an L-aromatic amino acid.

IPC Classes  ?

• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine

Abstract

The present invention relates to a microorganism that produces 1,4-butanediol and a method of producing 1,4-butanediol using same. The microorganism according to the present invention is able to efficiently produce 1,4-butanediol using ornithine as a carbon source, unlike naturally occurring microorganisms.

IPC Classes  ?

• C12P 7/16 - Butanols
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
• C12N 9/06 - Oxidoreductases (1.), e.g. luciferase acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
• C12N 9/80 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides

Abstract

The present invention relates to a novel stress protein variant and a method of producing an L-aromatic amino acid using the same. The stress protein variant is obtained by substituting one or more amino acids in the amino acid sequence constituting glutathione reductase or stress protein B to change the activity of the protein, and a recombinant microorganism comprising the variant is capable of efficiently producing an L-aromatic amino acid.

IPC Classes  ?

• C12P 13/22 - TryptophanTyrosinePhenylalanine3,4-Dihydroxyphenylalanine
• C12N 1/20 - BacteriaCulture media therefor
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli

Abstract

Escherichia coli. Therefore, by using a recombinant strain transformed with an expression vector including the novel promoter variant according to the present disclosure, it is possible to economically mass-produce a target protein, particularly an enzyme. For example, by using a recombinant strain transformed with an expression vector including the novel promoter variant according to the present disclosure, it is possible to economically mass-produce allulose epimerase or economically mass-produce allulose from fructose.

IPC Classes  ?

• C12N 9/90 - Isomerases (5.)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 19/02 - Monosaccharides
• C12P 19/24 - Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose

Abstract

The present invention relates to a microorganism of the genus Corynebacterium having enhanced L-arginine productivity and a method for producing L-arginine using same. The microorganism of the genus Corynebacterium has an improved L-arginine production yield, compared to the parent strain, by having, introduced thereinto, the argO gene encoding an arginine exporter, and thus can effectively produce L-arginine.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C07K 14/245 - Escherichia (G)
• C12P 13/10 - CitrullineArginineOrnithine

Abstract

The present invention provides a novel promoter variant in which some nucleotides of the glyceraldehyde-3-phosphate dehydrogenase (gapA) gene promoter of Escherichia coli are deleted. The novel promoter variant according to the present invention can constitutively express a target protein at a high level, particularly an enzyme, in Escherichia coli. Therefore, a target protein, particularly an enzyme, can be economically mass-produced using a recombinant strain transformed with an expression vector containing the novel promoter variant according to the present invention. For example, allulose epimerase can be economically mass-produced or allulose can be economically mass-produced from fructose using a recombinant strain transformed with an expression vector containing the novel promoter variant according to the present invention.

IPC Classes  ?

• C12P 19/02 - Monosaccharides
• C12N 1/20 - BacteriaCulture media therefor
• C12N 9/90 - Isomerases (5.)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12R 1/19 - Escherichia coli

Abstract

The present invention relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The Corynebacterium glutamicum mutant strain is able to produce L-lysine in an improved yield as a result of improving the activity of glyceraldehyde 3-phosphate dehydrogenase by mutagenesis of amino acids in the gene encoding glyceraldehyde 3-phosphate dehydrogenase.

IPC Classes  ?

• C12P 13/08 - LysineDiaminopimelic acidThreonineValine
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase

Abstract

The present invention relates to a novel variant of the GNAT family N-acetyltransferase and a method for producing L-glutamic acid using same. In the variant of the GNAT family N-acetyltransferase, one or more amino acids in the amino acid sequence constituting the GNAT family N-acetyltransferase are substituted, resulting in a change in protein activity. Accordingly, L-glutamic acid can be efficiently produced from a recombinant microorganism expressing the variant.

IPC Classes  ?

• C12N 9/10 - Transferases (2.)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

Abstract

The present invention relates to a novel 2-methylcitrate dehydratase variant and a method for producing L-glutamic acid using same. The 2-methylcitrate dehydratase variant has changed protein activity due to the substitution of at least one amino acid in an amino acid sequence constituting a 2-methylcitrate dehydratase, and thus, L-glutamic acid can be efficiently produced from a recombinant microorganism expressing the variant.

IPC Classes  ?

• C12N 9/88 - Lyases (4.)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

Abstract

The present invention relates to a novel mutant of MtrAB system accessory protein LpqB and a method for producing L-glutamic acid using same. The mutant of MtrAB system accessory protein LpqB has changed protein activity obtained by substituting at least one amino acid among amino acid sequences constituting the MtrAB system accessory protein LpqB, and thus L-glutamic acid can be efficiently produced from a recombinant microorganism expressing the mutant.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

Abstract

The present invention relates to a novel alkylhydroperoxidase AhpD family core domain variant, and a method for producing L-glutamic acid by using same. In the alkylhydroperoxidase AhpD family core domain variant, at least one amino acid from among amino acid sequences constituting the alkylhydroperoxidase AhpD family core domain is substituted such that protein activity is altered, and thus L-glutamic acid can be efficiently produced from a recombinant microorganism expressing the variant.

IPC Classes  ?

• C12N 9/08 - Oxidoreductases (1.), e.g. luciferase acting on hydrogen peroxide as acceptor (1.11)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

Abstract

The present invention relates to a novel 4-hydroxyphenyl-beta-ketoacyl-CoA hydrolase variant and a method for producing L-glutamic acid using same. Since the 4-hydroxyphenyl-beta-ketoacyl-CoA hydrolase variant has an altered protein activity due to substitution for at least one amino acid on the amino acid sequence constituting 4-hydroxyphenyl-beta-ketoacyl-CoA hydrolase, L-glutamic acid can be effectively produced from the recombinant microorganism expressing the variant.

IPC Classes  ?

• C12N 9/16 - Hydrolases (3.) acting on ester bonds (3.1)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

Abstract

The present invention relates to a genus Corynebacterium microorganism with improved L-glutamic acid productivity, and a method for producing L-glutamic acid by using same. The genus Corynebacterium microorganism has weakened or inactivated activity of polyphosphate kinase 2B, thereby having enhanced L-glutamic acid biosynthesis pathway, and thus can have better L-glutamic acid production yield than a parent strain.

IPC Classes  ?

• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12N 9/16 - Hydrolases (3.) acting on ester bonds (3.1)
• C12P 13/14 - Glutamic acidGlutamine
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli

Abstract

The present invention relates to a Corynebacterium sp. microorganism that produces L-glutamic acid and a method for producing L-glutamic acid using same and, specifically, to a myo-inositol facilitator IolT2 variant involved in the biosynthesis pathway of L-glutamic acid, a polynucleotide, and a transformant, as well as a method for producing L-glutamic acid using same. The myo-inositol facilitator IolT2 variant according to the present invention has altered protein activity due to the substitution of one or more amino acids in the amino acid sequence that constitutes IolT2, and a recombinant microorganism containing the variant can efficiently produce L-glutamic acid.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/14 - Glutamic acidGlutamine
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a corynebacterium sp. microorganism for producing L-glutamic acid, and a method for producing L-glutamic acid by using same, and, particularly, to: a variant, a polynucleotide and a transformant of transcriptional regulator IolR involved in the L-glutamic acid biosynthesis pathway; and a method for producing L-glutamic acid by using same. The transcriptional regulator IolR variant according to the present invention has one or more amino acids substituted in the amino acid sequence constituting the transcriptional regulator IolR, and thus the activity of the protein is altered such that a recombinant microorganism comprising the variant can efficiently produce L-glutamic acid.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 13/14 - Glutamic acidGlutamine

Abstract

The present invention relates to a novel variant of PTS transporter subunit EIIC and a 5'-inosinic acid production method using same. The variant of PTS transporter subunit EIIC has, by the substitution of at least one amino acid in the amino acid sequence constituting a PTS transporter subunit EIIC, changed protein activity, and thus a recombinant microorganism including the variant of PTS transporter subunit EIIC can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel variant of (p)ppGpp synthetase and a method for producing 5'-inosinic acid using same, the (p)ppGpp synthetase variant having altered protein activity due to substitution of one or more amino acids in the amino acid sequence constituting (p)ppGpp synthetase, thereby allowing recombinant microorganisms comprising the variant to efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium

Abstract

The present invention relates to a novel variant of phosphotransferase and a method for producing 5'-inosinic acid using same, the phosphotransferase variant having altered protein activity due to substitution of one or more amino acids in the amino acid sequence constituting phosphotransferase, thereby allowing recombinant microorganisms comprising the variant to efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel variant of pyruvate dehydrogenase and a method for producing 5'-inosinic acid using same, the pyruvate dehydrogenase variant having altered protein activity due to substitution of one or more amino acids in the amino acid sequence constituting pyruvate dehydrogenase, thereby allowing recombinant microorganisms comprising the variant to efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel variant of aldehyde dehydrogenase and a method for producing 5'-inosinic acid using same, the aldehyde dehydrogenase variant having altered protein activity due to substitution of one or more amino acids in the amino acid sequence constituting aldehyde dehydrogenase, thereby allowing recombinant microorganisms comprising the variant to efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel Fe-S cluster assembly protein SufB variant and a method for producing 5'-inosinic acid using same. The Fe-S cluster assembly protein SufB variant has modified protein activity due to the substitution of one or more amino acids in the amino acid sequence constituting the Fe-S cluster assembly protein SufB, and thus recombinant microorganisms comprising same can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a novel Fe-S cluster assembly protein SufD variant and a method for producing 5'-inosinic acid using same. The Fe-S cluster assembly protein SufD variant has modified protein activity due to the substitution of one or more amino acids in the amino acid sequence constituting the Fe-S cluster assembly protein SufD, and thus recombinant microorganisms comprising same can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a novel Fe-S cluster assembly protein SufC variant and a method for producing 5'-inosinic acid using same. The Fe-S cluster assembly protein SufC variant has modified protein activity due to the substitution of one or more amino acids in the amino acid sequence constituting the Fe-S cluster assembly protein SufC, and thus recombinant microorganisms comprising same can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
• C12R 1/15 - Corynebacterium

Abstract

The present invention relates to a novel variant of nucleotide hydrolase and a method for producing 5'-inosinic acid using same, the nucleotide hydrolase variant having altered protein activity due to substitution of one or more amino acids in the amino acid sequence constituting nucleotide hydrolase, thereby allowing recombinant microorganisms comprising the variant to efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/16 - Hydrolases (3.) acting on ester bonds (3.1)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel 5-dehydro-2-deoxygluconokinase variant and a method for producing 5'-inosinic acid using same. The 5-dehydro-2-deoxygluconokinase variant has modified protein activity due to the substitution of one or more amino acids in the amino acid sequence constituting 5-dehydro-2-deoxygluconokinase, and thus recombinant microorganisms comprising same can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel phosphoenolpyruvate carboxylase variant and a method for producing 5'-inosinic acid using same. The phosphoenolpyruvate carboxylase variant has modified protein activity due to the substitution of one or more amino acids in the amino acid sequence constituting phosphoenolpyruvate carboxylase, and thus recombinant microorganisms comprising same can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/88 - Lyases (4.)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel variant of threonine ammonia-lyase and a method for producing 5'-inosinic acid using same, the threonine ammonia-lyase variant having altered protein activity due to substitution of one or more amino acids in the amino acid sequence constituting threonine ammonia-lyase, thereby allowing recombinant microorganisms comprising the variant to efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/88 - Lyases (4.)
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Abstract

The present invention relates to a novel ABC transporter permease variant and a method for producing 5'-inosinic acid using same. The ABC transporter permease variant has modified protein activity due to the substitution of one or more amino acids in the amino acid sequence constituting an ABC transporter permease, and thus recombinant microorganisms comprising same can efficiently produce 5'-inosinic acid.

IPC Classes  ?

• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C12P 19/32 - Nucleotides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
• C12N 15/77 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for CorynebacteriumVectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Brevibacterium